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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79434560
log Bayes Factor = 18.5118
Chromosome 15   position 67,049,150  (GRCh37) Explore rs79434560 on Ensembl!
Variant rs79434560 is part of Cluster X0238

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.988 0.012 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.985 0.015 0.000
J90-J94 Other diseases of pleura
0.984 0.016 0.000
K70-K77 Diseases of liver
0.983 0.017 0.000
K22 Other diseases of oesophagus
0.981 0.019 0.000
F10.1 Harmful use
0.979 0.021 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.978 0.022 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.975 0.025 0.000
K31 Other diseases of stomach and duodenum
0.969 0.031 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.968 0.032 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.965 0.035 0.000
Chapter XX External causes of morbidity and mortality
0.964 0.036 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.964 0.036 0.000
I35 Nonrheumatic aortic valve disorders
0.962 0.038 0.000
K70 Alcoholic liver disease
0.962 0.038 0.000
I05-I09 Chronic rheumatic heart diseases
0.961 0.039 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.959 0.041 0.000
F10.3 Withdrawal state
0.958 0.042 0.000
J93 Pneumothorax
0.949 0.051 0.000
I47 Paroxysmal tachycardia
0.948 0.052 0.000
K31.8 Other specified diseases of stomach and duodenum
0.945 0.055 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.944 0.056 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.942 0.058 0.000
C34 Malignant neoplasm of bronchus and lung
0.941 0.059 0.000
J30-J39 Other diseases of upper respiratory tract
0.939 0.061 0.000
C15-C26 Malignant neoplasms of digestive organs
0.939 0.061 0.000
J95-J99 Other diseases of the respiratory system
0.938 0.062 0.000
S20-S29 Injuries to the thorax
0.937 0.063 0.000
K90-K93 Other diseases of the digestive system
0.932 0.068 0.000
R45 Symptoms and signs involving emotional state
0.932 0.068 0.000
S06 Intracranial injury
0.931 0.069 0.000
I47.1 Supraventricular tachycardia
0.928 0.072 0.000
Chapter XXI Factors influencing health status and contact with health services
0.928 0.072 0.000
S02 Fracture of skull and facial bones
0.927 0.073 0.000
I44 Atrioventricular and left bundle-branch block
0.926 0.074 0.000
J93.9 Pneumothorax, unspecified
0.921 0.079 0.000
C78.2 Secondary malignant neoplasm of pleura
0.916 0.084 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.912 0.088 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.910 0.090 0.000
I08 Multiple valve diseases
0.905 0.095 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.905 0.095 0.000
W00-W19 Falls
0.904 0.096 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.903 0.097 0.000
C34.9 Bronchus or lung, unspecified
0.901 0.099 0.000
K22.2 Oesophageal obstruction
0.899 0.101 0.000
F41 Other anxiety disorders
0.894 0.106 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.893 0.107 0.000
J98 Other respiratory disorders
0.891 0.109 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.891 0.109 0.000
R04 Haemorrhage from respiratory passages
0.889 0.111 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.888 0.112 0.000
K70.3 Alcoholic cirrhosis of liver
0.887 0.113 0.000
Z51 Other medical care
0.881 0.119 0.000
K92 Other diseases of digestive system
0.876 0.124 0.000
I42 Cardiomyopathy
0.875 0.125 0.000
C78.0 Secondary malignant neoplasm of lung
0.875 0.125 0.000
I34 Nonrheumatic mitral valve disorders
0.873 0.127 0.000
F41.9 Anxiety disorder, unspecified
0.873 0.127 0.000
R00 Abnormalities of heart beat
0.873 0.127 0.000
S27 Injury of other and unspecified intrathoracic organs
0.873 0.127 0.000
A30-A49 Other bacterial diseases
0.871 0.129 0.000
S10-S19 Injuries to the neck
0.871 0.129 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.870 0.130 0.000
Chapter VIII Diseases of the ear and mastoid process
0.868 0.132 0.000
K21 Gastro-oesophageal reflux disease
0.867 0.133 0.000
C18 Malignant neoplasm of colon
0.864 0.136 0.000
A00-A09 Intestinal infectious diseases
0.863 0.137 0.000
J92 Pleural plaque
0.863 0.137 0.000
F10.0 Acute intoxication
0.856 0.144 0.000
C64-C68 Malignant neoplasms of urinary tract
0.855 0.145 0.000
I35.1 Aortic (valve) insufficiency
0.851 0.149 0.000
S06.2 Diffuse brain injury
0.851 0.149 0.000
R04.0 Epistaxis
0.849 0.151 0.000
J32 Chronic sinusitis
0.846 0.154 0.000
S00 Superficial injury of head
0.846 0.154 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.845 0.155 0.000
I44.2 Atrioventricular block, complete
0.843 0.157 0.000
J91 Pleural effusion in conditions classified elsewhere
0.842 0.158 0.000
J98.4 Other disorders of lung
0.841 0.159 0.000
I73 Other peripheral vascular diseases
0.841 0.159 0.000
I05 Rheumatic mitral valve diseases
0.840 0.160 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.838 0.162 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.838 0.162 0.000
I35.0 Aortic (valve) stenosis
0.838 0.162 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.837 0.163 0.000
R06 Abnormalities of breathing
0.835 0.165 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.835 0.165 0.000
K92.0 Haematemesis
0.834 0.166 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.832 0.168 0.000
A04 Other bacterial intestinal infections
0.832 0.168 0.000
R45.1 Restlessness and agitation
0.831 0.169 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.830 0.170 0.000
K22.1 Ulcer of oesophagus
0.829 0.171 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.829 0.171 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.826 0.174 0.000
K90 Intestinal malabsorption
0.825 0.175 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.822 0.178 0.000
F10.2 Dependence syndrome
0.821 0.179 0.000
T66-T78 Other and unspecified effects of external causes
0.820 0.180 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.819 0.181 0.000
F60-F69 Disorders of adult personality and behaviour
0.819 0.181 0.000
S27.0 Traumatic pneumothorax
0.819 0.181 0.000
I35.9 Aortic valve disorder, unspecified
0.819 0.181 0.000
J20-J22 Other acute lower respiratory infections
0.819 0.181 0.000
K22.5 Diverticulum of oesophagus, acquired
0.817 0.183 0.000
R45.8 Other symptoms and signs involving emotional state
0.817 0.183 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.816 0.184 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.816 0.184 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.816 0.184 0.000
J00-J06 Acute upper respiratory infections
0.815 0.185 0.000
K22.4 Dyskinesia of oesophagus
0.815 0.185 0.000
I51 Complications and ill-defined descriptions of heart disease
0.815 0.185 0.000
F99-F99 Unspecified mental disorder
0.815 0.185 0.000
I44.0 Atrioventricular block, first degree
0.815 0.185 0.000
R00.2 Palpitations
0.814 0.186 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.813 0.187 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.813 0.187 0.000
C25 Malignant neoplasm of pancreas
0.812 0.188 0.000
J09-J18 Influenza and pneumonia
0.811 0.189 0.000
R05 Cough
0.808 0.192 0.000
Z50 Care involving use of rehabilitation procedures
0.808 0.192 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
K70.4 Alcoholic hepatic failure
0.806 0.194 0.000
J60-J70 Lung diseases due to external agents
0.805 0.195 0.000
K26 Duodenal ulcer
0.804 0.196 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.803 0.197 0.000
C79 Secondary malignant neoplasm of other sites
0.803 0.197 0.000
H90-H95 Other disorders of ear
0.802 0.198 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.802 0.198 0.000
K70.1 Alcoholic hepatitis
0.802 0.198 0.000
K74 Fibrosis and cirrhosis of liver
0.801 0.199 0.000
I73.9 Peripheral vascular disease, unspecified
0.801 0.199 0.000
A04.8 Other specified bacterial intestinal infections
0.800 0.200 0.000
I31 Other diseases of pericardium
0.800 0.200 0.000
Z51.3 Blood transfusion without reported diagnosis
0.799 0.201 0.000
I74 Arterial embolism and thrombosis
0.798 0.202 0.000
K31.5 Obstruction of duodenum
0.796 0.204 0.000
K92.1 Melaena
0.796 0.204 0.000
K70.9 Alcoholic liver disease, unspecified
0.796 0.204 0.000
C51-C58 Malignant neoplasms of female genital organs
0.795 0.205 0.000
J34 Other disorders of nose and nasal sinuses
0.795 0.205 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.795 0.205 0.000
V10-V19 Pedal cyclist injured in transport accident
0.794 0.206 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.793 0.207 0.000
K29 Gastritis and duodenitis
0.793 0.207 0.000
R18 Ascites
0.792 0.208 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.791 0.209 0.000
Z45 Adjustment and management of implanted device
0.790 0.210 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.788 0.212 0.000
K76 Other diseases of liver
0.787 0.213 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.786 0.214 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.784 0.216 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.784 0.216 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.784 0.216 0.000
C34.1 Upper lobe, bronchus or lung
0.784 0.216 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.783 0.217 0.000
R12 Heartburn
0.783 0.217 0.000
I46 Cardiac arrest
0.781 0.219 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.780 0.220 0.000
A49 Bacterial infection of unspecified site
0.779 0.221 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.778 0.222 0.000
W19 Unspecified fall
0.777 0.223 0.000
Z42 Follow-up care involving plastic surgery
0.777 0.223 0.000
I72 Other aneurysm
0.777 0.223 0.000
I51.7 Cardiomegaly
0.776 0.224 0.000
T51 Toxic effect of alcohol
0.775 0.225 0.000
D47.1 Chronic myeloproliferative disease
0.774 0.226 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.773 0.227 0.000
I34.0 Mitral (valve) insufficiency
0.772 0.228 0.000
R45.2 Unhappiness
0.772 0.228 0.000
I42.8 Other cardiomyopathies
0.771 0.229 0.000
K25 Gastric ulcer
0.768 0.232 0.000
J81 Pulmonary oedema
0.767 0.233 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.763 0.237 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.762 0.237 0.000
S02.4 Fracture of malar and maxillary bones
0.761 0.239 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.759 0.241 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.758 0.242 0.000
K72 Hepatic failure, not elsewhere classified
0.758 0.242 0.000
Z52 Donors of organs and tissues
0.755 0.245 0.000
I71 Aortic aneurysm and dissection
0.755 0.245 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.755 0.245 0.000
R47-R49 Symptoms and signs involving speech and voice
0.755 0.245 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.754 0.246 0.000
W18 Other fall on same level
0.753 0.247 0.000
S02.1 Fracture of base of skull
0.753 0.247 0.000
C34.3 Lower lobe, bronchus or lung
0.753 0.247 0.000
I08.0 Disorders of both mitral and aortic valves
0.752 0.248 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.751 0.248 0.000
S02.2 Fracture of nasal bones
0.751 0.249 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.750 0.250 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.749 0.251 0.000
X20-X29 Contact with venomous animals and plants
0.749 0.251 0.000
F43 Reaction to severe stress, and adjustment disorders
0.749 0.251 0.000
J32.9 Chronic sinusitis, unspecified
0.749 0.251 0.000
I30 Acute pericarditis
0.748 0.252 0.000
J32.8 Other chronic sinusitis
0.748 0.252 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.748 0.252 0.000
K65-K67 Diseases of peritoneum
0.747 0.253 0.000
R46 Symptoms and signs involving appearance and behaviour
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.746 0.254 0.000
S06.4 Epidural haemorrhage
0.746 0.254 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.746 0.254 0.000
K22.7 Barrett's oesophagus
0.745 0.255 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.744 0.256 0.000
J92.9 Pleural plaque without asbestos
0.743 0.257 0.000
S20 Superficial injury of thorax
0.743 0.257 0.000
I27 Other pulmonary heart diseases
0.742 0.258 0.000
J80 Adult respiratory distress syndrome
0.740 0.259 0.000
S02.0 Fracture of vault of skull
0.739 0.261 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.739 0.261 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.737 0.262 0.000
C65 Malignant neoplasm of renal pelvis
0.737 0.263 0.000
S01 Open wound of head
0.737 0.263 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.736 0.264 0.000
T42.4 Benzodiazepines
0.734 0.266 0.000
W20-W49 Exposure to inanimate mechanical forces
0.734 0.266 0.000
C18.4 Transverse colon
0.734 0.266 0.000
C18.1 Appendix
0.733 0.267 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.732 0.268 0.000
D37.5 Rectum
0.732 0.268 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.732 0.268 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
F41.1 Generalised anxiety disorder
0.729 0.271 0.000
Z51.2 Other chemotherapy
0.728 0.272 0.000
T63 Toxic effect of contact with venomous animals
0.728 0.272 0.000
Chapter XXII Codes for special purposes
0.727 0.273 0.000
I99 Other and unspecified disorders of circulatory system
0.726 0.274 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.725 0.275 0.000
D46 Myelodysplastic syndromes
0.723 0.277 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.723 0.277 0.000
I44.3 Other and unspecified atrioventricular block
0.722 0.278 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.719 0.280 0.000
D38.1 Trachea, bronchus and lung
0.719 0.281 0.000
J93.1 Other spontaneous pneumothorax
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
I08.8 Other multiple valve diseases
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.716 0.284 0.000
K29.5 Chronic gastritis, unspecified
0.716 0.284 0.000
K28 Gastrojejunal ulcer
0.715 0.285 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.715 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.285 0.000
R44.0 Auditory hallucinations
0.714 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.714 0.286 0.000
F10.8 Other mental and behavioural disorders
0.714 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F10.6 Amnesic syndrome
0.714 0.286 0.000
F10.5 Psychotic disorder
0.714 0.286 0.000
F10.4 Withdrawal state with delirium
0.714 0.286 0.000
I35.8 Other aortic valve disorders
0.714 0.286 0.000
I33 Acute and subacute endocarditis
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
J98.9 Respiratory disorder, unspecified
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
R42 Dizziness and giddiness
0.709 0.291 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.708 0.291 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.291 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.708 0.291 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.708 0.291 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.708 0.291 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.708 0.291 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.708 0.291 0.000
T36 Poisoning by systemic antibiotics
0.708 0.291 0.000
S08 Traumatic amputation of part of head
0.708 0.291 0.000
S07 Crushing injury of head
0.708 0.291 0.000
S05 Injury of eye and orbit
0.708 0.291 0.000
S04 Injury of cranial nerves
0.708 0.291 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.291 0.000
I45 Other conduction disorders
0.708 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.706 0.294 0.000
J37 Chronic laryngitis and laryngotracheitis
0.706 0.294 0.000
C18.3 Hepatic flexure
0.705 0.295 0.000
K77 Liver disorders in diseases classified elsewhere
0.705 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.705 0.295 0.000
K71 Toxic liver disease
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.704 0.296 0.000
W13 Fall from, out of or through building or structure
0.704 0.296 0.000
K22.3 Perforation of oesophagus
0.703 0.297 0.000
K22.0 Achalasia of cardia
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.703 0.297 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.702 0.298 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.701 0.299 0.000
Z54 Convalescence
0.701 0.299 0.000
S00.0 Superficial injury of scalp
0.701 0.299 0.000
J02 Acute pharyngitis
0.701 0.299 0.000
Z50.5 Speech therapy
0.701 0.299 0.000
C92 Myeloid leukaemia
0.701 0.299 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.700 0.300 0.000
S02.5 Fracture of tooth
0.700 0.300 0.000
J94 Other pleural conditions
0.700 0.300 0.000
J34.3 Hypertrophy of nasal turbinates
0.700 0.300 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.699 0.301 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.699 0.301 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.699 0.301 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.699 0.301 0.000
Z47 Other orthopaedic follow-up care
0.699 0.301 0.000
C15 Malignant neoplasm of oesophagus
0.698 0.302 0.000
K76.6 Portal hypertension
0.698 0.302 0.000
S19 Other and unspecified injuries of neck
0.698 0.302 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.697 0.302 0.000
R06.4 Hyperventilation
0.697 0.303 0.000
Z45.2 Adjustment and management of vascular access device
0.697 0.303 0.000
Z51.0 Radiotherapy session
0.697 0.303 0.000
W07 Fall involving chair
0.696 0.304 0.000
Z50.2 Alcohol rehabilitation
0.696 0.304 0.000
R06.8 Other and unspecified abnormalities of breathing
0.696 0.304 0.000
J39 Other diseases of upper respiratory tract
0.696 0.304 0.000
X60-X84 Intentional self-harm
0.696 0.304 0.000
B15-B19 Viral hepatitis
0.695 0.305 0.000
K31.6 Fistula of stomach and duodenum
0.695 0.305 0.000
K31.4 Gastric diverticulum
0.695 0.305 0.000
K31.3 Pylorospasm, not elsewhere classified
0.695 0.305 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.695 0.305 0.000
K31.0 Acute dilatation of stomach
0.695 0.305 0.000
K20 Oesophagitis
0.694 0.306 0.000
R43 Disturbances of smell and taste
0.694 0.306 0.000
F80-F89 Disorders of psychological development
0.693 0.307 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.693 0.307 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.692 0.308 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.692 0.308 0.000
C32 Malignant neoplasm of larynx
0.692 0.308 0.000
C31 Malignant neoplasm of accessory sinuses
0.692 0.308 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.692 0.308 0.000
C37 Malignant neoplasm of thymus
0.692 0.308 0.000
C33 Malignant neoplasm of trachea
0.692 0.308 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.692 0.308 0.000
I50 Heart failure
0.692 0.308 0.000
T78 Adverse effects, not elsewhere classified
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
Y00-Y09 Assault
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X10-X19 Contact with heat and hot substances
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W75-W84 Other accidental threats to breathing
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
W50-W64 Exposure to animate mechanical forces
0.691 0.309 0.000
V98-V99 Other and unspecified transport accidents
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
H93 Other disorders of ear, not elsewhere classified
0.691 0.309 0.000
R44.1 Visual hallucinations
0.690 0.309 0.000
B25-B34 Other viral diseases
0.690 0.310 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.690 0.310 0.000
K70.0 Alcoholic fatty liver
0.690 0.310 0.000
F60 Specific personality disorders
0.690 0.310 0.000
A41 Other septicaemia
0.689 0.311 0.000
I09 Other rheumatic heart diseases
0.689 0.311 0.000
I06 Rheumatic aortic valve diseases
0.689 0.311 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.689 0.311 0.000
J22 Unspecified acute lower respiratory infection
0.689 0.311 0.000
T51.0 Ethanol
0.688 0.311 0.000
F45 Somatoform disorders
0.688 0.312 0.000
S14 Injury of nerves and spinal cord at neck level
0.688 0.312 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.688 0.312 0.000
S02.8 Fractures of other skull and facial bones
0.688 0.312 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.688 0.312 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.688 0.312 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.688 0.312 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.688 0.312 0.000
K27 Peptic ulcer, site unspecified
0.687 0.312 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.687 0.313 0.000
J38.1 Polyp of vocal cord and larynx
0.687 0.313 0.000
C18.7 Sigmoid colon
0.687 0.313 0.000
K90.9 Intestinal malabsorption, unspecified
0.686 0.314 0.000
J92.0 Pleural plaque with presence of asbestos
0.686 0.314 0.000
A40 Streptococcal septicaemia
0.685 0.315 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.685 0.315 0.000
Chapter XIV Diseases of the genitourinary system
0.685 0.315 0.000
C25.9 Pancreas, unspecified
0.685 0.315 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.684 0.316 0.000
D00-D09 In situ neoplasms
0.682 0.318 0.000
F99 Mental disorder, not otherwise specified
0.682 0.318 0.000
I44.1 Atrioventricular block, second degree
0.682 0.318 0.000
Z51.1 Chemotherapy session for neoplasm
0.681 0.319 0.000
R40 Somnolence, stupor and coma
0.681 0.319 0.000
J93.8 Other pneumothorax
0.681 0.319 0.000
J93.0 Spontaneous tension pneumothorax
0.681 0.319 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.681 0.319 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.680 0.320 0.000
I47.0 Reentry ventricular arrhythmia
0.680 0.320 0.000
C66 Malignant neoplasm of ureter
0.680 0.320 0.000
I38 Endocarditis, valve unspecified
0.680 0.320 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.679 0.321 0.000
S06.5 Traumatic subdural haemorrhage
0.678 0.322 0.000
F48 Other neurotic disorders
0.677 0.323 0.000
F44 Dissociative [conversion] disorders
0.677 0.323 0.000
F42 Obsessive-compulsive disorder
0.677 0.323 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.676 0.323 0.000
I05.1 Rheumatic mitral insufficiency
0.676 0.324 0.000
I42.0 Dilated cardiomyopathy
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B65-B83 Helminthiases
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
Y43 Primarily systemic agents
0.675 0.324 0.000
C34.8 Overlapping lesion of bronchus and lung
0.674 0.325 0.000
C34.2 Middle lobe, bronchus or lung
0.674 0.325 0.000
I05.0 Mitral stenosis
0.674 0.326 0.000
J31.0 Chronic rhinitis
0.673 0.327 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.673 0.327 0.000
C21 Malignant neoplasm of anus and anal canal
0.673 0.327 0.000
C17 Malignant neoplasm of small intestine
0.673 0.327 0.000
C23 Malignant neoplasm of gallbladder
0.673 0.327 0.000
C45 Mesothelioma
0.673 0.327 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.673 0.327 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.672 0.327 0.000
J96 Respiratory failure, not elsewhere classified
0.672 0.327 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.672 0.328 0.000
F03 Unspecified dementia
0.672 0.328 0.000
S29 Other and unspecified injuries of thorax
0.671 0.328 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.671 0.328 0.000
S26 Injury of heart
0.671 0.328 0.000
S25 Injury of blood vessels of thorax
0.671 0.328 0.000
S24 Injury of nerves and spinal cord at thorax level
0.671 0.328 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.671 0.328 0.000
S21 Open wound of thorax
0.671 0.328 0.000
S50-S59 Injuries to the elbow and forearm
0.671 0.329 0.000
R07 Pain in throat and chest
0.671 0.329 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.670 0.330 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.670 0.330 0.000
R10 Abdominal and pelvic pain
0.670 0.330 0.000
K74.6 Other and unspecified cirrhosis of liver
0.670 0.330 0.000
S00.9 Superficial injury of head, part unspecified
0.669 0.331 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.668 0.331 0.000
R20 Disturbances of skin sensation
0.668 0.332 0.000
R45.7 State of emotional shock and stress, unspecified
0.668 0.332 0.000
R45.6 Physical violence
0.668 0.332 0.000
R45.5 Hostility
0.668 0.332 0.000
R45.4 Irritability and anger
0.668 0.332 0.000
R45.3 Demoralisation and apathy
0.668 0.332 0.000
R45.0 Nervousness
0.668 0.332 0.000
S06.9 Intracranial injury, unspecified
0.667 0.333 0.000
S06.8 Other intracranial injuries
0.667 0.333 0.000
S06.7 Intracranial injury with prolonged coma
0.667 0.333 0.000
S06.3 Focal brain injury
0.667 0.333 0.000
S06.1 Traumatic cerebral oedema
0.667 0.333 0.000
S06.0 Concussion
0.667 0.333 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.667 0.333 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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