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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79458143
log Bayes Factor = 17.4714
Chromosome 10   position 37,906,832  (GRCh37) Explore rs79458143 on Ensembl!
Variant rs79458143 is part of Cluster X0055

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
K55-K64 Other diseases of intestines
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.989 0.011 0.000
N18 Chronic renal failure
0.985 0.015 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.985 0.015 0.000
K50-K52 Noninfective enteritis and colitis
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
K52 Other non-infective gastro-enteritis and colitis
0.978 0.022 0.000
M80-M85 Disorders of bone density and structure
0.974 0.026 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.973 0.027 0.000
K56.6 Other and unspecified intestinal obstruction
0.973 0.027 0.000
N19 Unspecified renal failure
0.973 0.027 0.000
Chapter II Neoplasms
0.968 0.032 0.000
B95-B98 Bacterial, viral and other infectious agents
0.963 0.037 0.000
K59 Other functional intestinal disorders
0.961 0.039 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.957 0.043 0.000
M81 Osteoporosis without pathological fracture
0.957 0.043 0.000
E65-E68 Obesity and other hyperalimentation
0.957 0.043 0.000
I50 Heart failure
0.950 0.050 0.000
N60-N64 Disorders of breast
0.949 0.051 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.948 0.052 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.947 0.053 0.000
M81.9 Osteoporosis, unspecified
0.945 0.055 0.000
E86 Volume depletion
0.945 0.055 0.000
N18.9 Chronic renal failure, unspecified
0.941 0.059 0.000
E87.5 Hyperkalaemia
0.941 0.059 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.940 0.060 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.937 0.063 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.934 0.066 0.000
K59.0 Constipation
0.929 0.071 0.000
E66 Obesity
0.926 0.074 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.924 0.076 0.000
E00-E07 Disorders of thyroid gland
0.919 0.081 0.000
C15-C26 Malignant neoplasms of digestive organs
0.918 0.082 0.000
M15-M19 Arthrosis
0.917 0.083 0.000
Chapter XXII Codes for special purposes
0.910 0.090 0.000
M19 Other arthrosis
0.906 0.094 0.000
R04 Haemorrhage from respiratory passages
0.905 0.095 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.902 0.098 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.901 0.099 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.900 0.100 0.000
I50.1 Left ventricular failure
0.899 0.101 0.000
M19.9 Arthrosis, unspecified
0.898 0.102 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.890 0.110 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.887 0.113 0.000
S50-S59 Injuries to the elbow and forearm
0.887 0.113 0.000
B15-B19 Viral hepatitis
0.887 0.113 0.000
N20-N23 Urolithiasis
0.881 0.119 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.880 0.120 0.000
M70-M79 Other soft tissue disorders
0.877 0.123 0.000
E66.9 Obesity, unspecified
0.874 0.126 0.000
E87.2 Acidosis
0.873 0.127 0.000
S80-S89 Injuries to the knee and lower leg
0.872 0.128 0.000
N62 Hypertrophy of breast
0.867 0.133 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.867 0.133 0.000
K35-K38 Diseases of appendix
0.866 0.134 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.866 0.134 0.000
N00-N08 Glomerular diseases
0.858 0.141 0.000
C60-C63 Malignant neoplasms of male genital organs
0.856 0.144 0.000
I20-I25 Ischaemic heart diseases
0.854 0.146 0.000
E78.5 Hyperlipidaemia, unspecified
0.852 0.148 0.000
S20-S29 Injuries to the thorax
0.851 0.148 0.000
R04.0 Epistaxis
0.846 0.154 0.000
R04.2 Haemoptysis
0.844 0.156 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.843 0.157 0.000
N10-N16 Renal tubulo-interstitial diseases
0.842 0.158 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.841 0.159 0.000
Chapter XX External causes of morbidity and mortality
0.840 0.160 0.000
E87.6 Hypokalaemia
0.840 0.160 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.838 0.162 0.000
N18.4 Chronic kidney disease, stage 4
0.837 0.163 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.837 0.163 0.000
A30-A49 Other bacterial diseases
0.835 0.165 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.834 0.166 0.000
M19.94 Arthrosis, unspecified (Hand)
0.834 0.166 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.833 0.167 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.831 0.169 0.000
N17 Acute renal failure
0.830 0.170 0.000
K57 Diverticular disease of intestine
0.829 0.171 0.000
K60 Fissure and fistula of anal and rectal regions
0.827 0.173 0.000
S60-S69 Injuries to the wrist and hand
0.827 0.173 0.000
I33 Acute and subacute endocarditis
0.826 0.174 0.000
T66-T78 Other and unspecified effects of external causes
0.824 0.176 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.821 0.179 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.819 0.181 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.819 0.181 0.000
E66.8 Other obesity
0.817 0.183 0.000
L89 Decubitus ulcer
0.815 0.185 0.000
I38 Endocarditis, valve unspecified
0.814 0.186 0.000
I49 Other cardiac arrhythmias
0.808 0.192 0.000
S52 Fracture of forearm
0.807 0.193 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.807 0.193 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.803 0.197 0.000
M86-M90 Other osteopathies
0.803 0.197 0.000
I50.9 Heart failure, unspecified
0.802 0.198 0.000
K12 Stomatitis and related lesions
0.802 0.198 0.000
N60 Benign mammary dysplasia
0.801 0.199 0.000
I45 Other conduction disorders
0.800 0.200 0.000
S00-S09 Injuries to the head
0.800 0.200 0.000
N18.2 Chronic kidney disease, stage 2
0.798 0.202 0.000
E10-E14 Diabetes mellitus
0.797 0.203 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.796 0.204 0.000
C20 Malignant neoplasm of rectum
0.795 0.205 0.000
K37 Unspecified appendicitis
0.794 0.206 0.000
S82 Fracture of lower leg, including ankle
0.794 0.206 0.000
C16 Malignant neoplasm of stomach
0.792 0.208 0.000
K56.2 Volvulus
0.789 0.211 0.000
C44 Other malignant neoplasms of skin
0.789 0.211 0.000
R06 Abnormalities of breathing
0.786 0.214 0.000
N18.3 Chronic kidney disease, stage 3
0.785 0.215 0.000
B25-B34 Other viral diseases
0.785 0.215 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.785 0.215 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.783 0.217 0.000
E83 Disorders of mineral metabolism
0.781 0.219 0.000
K56.7 Ileus, unspecified
0.781 0.219 0.000
K80 Cholelithiasis
0.781 0.219 0.000
N18.0 End-stage renal disease
0.777 0.223 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.777 0.223 0.000
C61 Malignant neoplasm of prostate
0.777 0.223 0.000
I20 Angina pectoris
0.775 0.225 0.000
D45 Polycythaemia vera
0.774 0.226 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.774 0.226 0.000
K14 Diseases of tongue
0.773 0.226 0.000
E06 Thyroiditis
0.772 0.228 0.000
B18 Chronic viral hepatitis
0.772 0.228 0.000
M45-M49 Spondylopathies
0.771 0.229 0.000
E16 Other disorders of pancreatic internal secretion
0.771 0.229 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.767 0.233 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.766 0.234 0.000
I26 Pulmonary embolism
0.766 0.234 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.766 0.234 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.765 0.234 0.000
I34 Nonrheumatic mitral valve disorders
0.765 0.235 0.000
E87.0 Hyperosmolality and hypernatraemia
0.765 0.235 0.000
R07 Pain in throat and chest
0.765 0.235 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.764 0.236 0.000
Chapter V Mental and behavioural disorders
0.764 0.236 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.762 0.238 0.000
R94 Abnormal results of function studies
0.762 0.238 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.761 0.239 0.000
K59.8 Other specified functional intestinal disorders
0.760 0.239 0.000
N64 Other disorders of breast
0.760 0.240 0.000
I31 Other diseases of pericardium
0.758 0.242 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.758 0.242 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.756 0.244 0.000
E07 Other disorders of thyroid
0.756 0.244 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.755 0.245 0.000
K10 Other diseases of jaws
0.754 0.246 0.000
R47-R49 Symptoms and signs involving speech and voice
0.754 0.246 0.000
U80 Agent resistant to penicillin and related antibiotics
0.753 0.247 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
E40-E46 Malnutrition
0.752 0.248 0.000
K01 Embedded and impacted teeth
0.752 0.248 0.000
S40-S49 Injuries to the shoulder and upper arm
0.745 0.255 0.000
B35-B49 Mycoses
0.745 0.255 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.744 0.256 0.000
K02 Dental caries
0.744 0.256 0.000
K83 Other diseases of biliary tract
0.744 0.256 0.000
N99-N99 Other disorders of the genitourinary system
0.743 0.257 0.000
M77 Other enthesopathies
0.742 0.258 0.000
K61 Abscess of anal and rectal regions
0.742 0.258 0.000
I49.5 Sick sinus syndrome
0.741 0.259 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.741 0.259 0.000
R15 Faecal incontinence
0.741 0.259 0.000
R07.3 Other chest pain
0.741 0.259 0.000
I27 Other pulmonary heart diseases
0.740 0.260 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.740 0.260 0.000
K80.4 Calculus of bile duct with cholecystitis
0.739 0.261 0.000
K60.2 Anal fissure, unspecified
0.738 0.262 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.737 0.263 0.000
M80 Osteoporosis with pathological fracture
0.737 0.263 0.000
E87.7 Fluid overload
0.737 0.263 0.000
N23 Unspecified renal colic
0.737 0.263 0.000
I46 Cardiac arrest
0.736 0.264 0.000
K05 Gingivitis and periodontal diseases
0.735 0.265 0.000
I50.0 Congestive heart failure
0.734 0.266 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.733 0.266 0.000
I24 Other acute ischaemic heart diseases
0.733 0.267 0.000
N40-N51 Diseases of male genital organs
0.732 0.268 0.000
Chapter VIII Diseases of the ear and mastoid process
0.732 0.268 0.000
C44.3 Skin of other and unspecified parts of face
0.731 0.269 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.730 0.269 0.000
S27 Injury of other and unspecified intrathoracic organs
0.728 0.272 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.726 0.274 0.000
M79.6 Pain in limb
0.725 0.275 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.725 0.275 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.724 0.275 0.000
B17 Other acute viral hepatitis
0.724 0.276 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.723 0.277 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.723 0.277 0.000
E05.9 Thyrotoxicosis, unspecified
0.723 0.277 0.000
R06.0 Dyspnoea
0.722 0.278 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.721 0.279 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.721 0.279 0.000
R02 Gangrene, not elsewhere classified
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K56.4 Other impaction of intestine
0.717 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
I05-I09 Chronic rheumatic heart diseases
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
E88 Other metabolic disorders
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.716 0.284 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.715 0.285 0.000
K13 Other diseases of lip and oral mucosa
0.714 0.286 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.714 0.286 0.000
I33.0 Acute and subacute infective endocarditis
0.713 0.287 0.000
K07 Dentofacial anomalies [including malocclusion]
0.713 0.287 0.000
W00-W19 Falls
0.713 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.287 0.000
M85 Other disorders of bone density and structure
0.712 0.288 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
I35 Nonrheumatic aortic valve disorders
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.712 0.288 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.711 0.288 0.000
R11 Nausea and vomiting
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A80-A89 Viral infections of the central nervous system
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
T81 Complications of procedures, not elsewhere classified
0.710 0.290 0.000
C50-C50 Malignant neoplasm of breast
0.709 0.291 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.709 0.291 0.000
E87.4 Mixed disorder of acid-base balance
0.709 0.291 0.000
E87.3 Alkalosis
0.709 0.291 0.000
N17.9 Acute renal failure, unspecified
0.708 0.292 0.000
N03 Chronic nephritic syndrome
0.708 0.292 0.000
I42 Cardiomyopathy
0.708 0.292 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.708 0.292 0.000
N18.8 Other chronic renal failure
0.707 0.293 0.000
N18.1 Chronic kidney disease, stage 1
0.707 0.293 0.000
N93 Other abnormal uterine and vaginal bleeding
0.706 0.294 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.706 0.294 0.000
K56.3 Gallstone ileus
0.706 0.294 0.000
K56.1 Intussusception
0.706 0.294 0.000
K56.0 Paralytic ileus
0.706 0.294 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.705 0.294 0.000
Chapter VI Diseases of the nervous system
0.705 0.295 0.000
N20 Calculus of kidney and ureter
0.704 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
I30 Acute pericarditis
0.704 0.296 0.000
D46 Myelodysplastic syndromes
0.704 0.296 0.000
E16.2 Hypoglycaemia, unspecified
0.703 0.297 0.000
C25 Malignant neoplasm of pancreas
0.703 0.297 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.702 0.297 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.702 0.298 0.000
N13 Obstructive and reflux uropathy
0.702 0.298 0.000
L20-L30 Dermatitis and eczema
0.701 0.299 0.000
L50-L54 Urticaria and erythema
0.701 0.299 0.000
K52.3 Indeterminate colitis
0.701 0.299 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.701 0.299 0.000
K52.1 Toxic gastro-enteritis and colitis
0.701 0.299 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.701 0.299 0.000
N60.3 Fibrosclerosis of breast
0.701 0.299 0.000
M71 Other bursopathies
0.700 0.300 0.000
K86 Other diseases of pancreas
0.700 0.300 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.699 0.301 0.000
N95 Menopausal and other perimenopausal disorders
0.699 0.301 0.000
T78 Adverse effects, not elsewhere classified
0.698 0.301 0.000
A41 Other septicaemia
0.698 0.302 0.000
M84 Disorders of continuity of bone
0.698 0.302 0.000
M83 Adult osteomalacia
0.698 0.302 0.000
M82 Osteoporosis in diseases classified elsewhere
0.698 0.302 0.000
E20-E35 Disorders of other endocrine glands
0.698 0.302 0.000
I95 Hypotension
0.697 0.303 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.695 0.304 0.000
K30 Dyspepsia
0.695 0.305 0.000
N02 Recurrent and persistent haematuria
0.695 0.305 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.694 0.305 0.000
K59.3 Megacolon, not elsewhere classified
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.306 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.694 0.306 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.694 0.306 0.000
U80.1 Methicillin resistant agent
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.691 0.309 0.000
C15 Malignant neoplasm of oesophagus
0.690 0.310 0.000
M19.1 Posttraumatic arthrosis of other joints
0.690 0.310 0.000
N25-N29 Other disorders of kidney and ureter
0.690 0.310 0.000
B18.2 Chronic viral hepatitis C
0.689 0.311 0.000
L60-L75 Disorders of skin appendages
0.689 0.311 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.689 0.311 0.000
K59.9 Functional intestinal disorder, unspecified
0.689 0.311 0.000
K59.4 Anal spasm
0.689 0.311 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.689 0.311 0.000
K59.1 Functional diarrhoea
0.689 0.311 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.688 0.312 0.000
R94.5 Abnormal results of liver function studies
0.688 0.312 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.687 0.313 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.686 0.313 0.000
M81.8 Other osteoporosis
0.686 0.314 0.000
M81.6 Localised osteoporosis [Lequesne]
0.686 0.314 0.000
M81.5 Idiopathic osteoporosis
0.686 0.314 0.000
M81.4 Drug-induced osteoporosis
0.686 0.314 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.686 0.314 0.000
M81.2 Osteoporosis of disuse
0.686 0.314 0.000
M81.1 Postoophorectomy osteoporosis
0.686 0.314 0.000
M81.0 Postmenopausal osteoporosis
0.686 0.314 0.000
E67 Other hyperalimentation
0.686 0.314 0.000
E68 Sequelae of hyperalimentation
0.686 0.314 0.000
E65 Localised adiposity
0.686 0.314 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.685 0.315 0.000
K12.2 Cellulitis and abscess of mouth
0.685 0.315 0.000
C44.6 Skin of upper limb, including shoulder
0.685 0.315 0.000
E10 Insulin-dependent diabetes mellitus
0.683 0.317 0.000
K08 Other disorders of teeth and supporting structures
0.683 0.317 0.000
C16.0 Cardia
0.681 0.319 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.681 0.319 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.681 0.319 0.000
T87 Complications peculiar to reattachment and amputation
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.320 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.680 0.320 0.000
K09 Cysts of oral region, not elsewhere classified
0.679 0.321 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.679 0.321 0.000
K03 Other diseases of hard tissues of teeth
0.679 0.321 0.000
K00 Disorders of tooth development and eruption
0.679 0.321 0.000
S64 Injury of nerves at wrist and hand level
0.679 0.321 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.679 0.321 0.000
N61 Inflammatory disorders of breast
0.679 0.321 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.678 0.321 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.678 0.322 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.678 0.322 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.678 0.322 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.678 0.322 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.678 0.322 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.678 0.322 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.678 0.322 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.678 0.322 0.000
S52.8 Fracture of other parts of forearm
0.677 0.323 0.000
K50 Crohn's disease [regional enteritis]
0.676 0.324 0.000
K70-K77 Diseases of liver
0.676 0.324 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.676 0.324 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.675 0.324 0.000
M81.98 Osteoporosis, unspecified (Other)
0.675 0.325 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.674 0.326 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.674 0.326 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.674 0.326 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.674 0.326 0.000
N81 Female genital prolapse
0.674 0.326 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.673 0.327 0.000
C44.4 Skin of scalp and neck
0.673 0.327 0.000
N30-N39 Other diseases of urinary system
0.673 0.327 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.673 0.327 0.000
M79.67 Pain in limb (Ankle and foot)
0.672 0.328 0.000
L10-L14 Bullous disorders
0.672 0.328 0.000
N21 Calculus of lower urinary tract
0.671 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
N18.5 Chronic kidney disease, stage 5
0.670 0.330 0.000
R14 Flatulence and related conditions
0.669 0.330 0.000
I20.0 Unstable angina
0.669 0.331 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.668 0.332 0.000
S02 Fracture of skull and facial bones
0.668 0.332 0.000
K11 Diseases of salivary glands
0.668 0.332 0.000
E06.3 Autoimmune thyroiditis
0.667 0.333 0.000
C51-C58 Malignant neoplasms of female genital organs
0.667 0.333 0.000
K81 Cholecystitis
0.667 0.333 0.000
S01 Open wound of head
0.666 0.334 0.000
L82 Seborrhoeic keratosis
0.666 0.334 0.000
C18 Malignant neoplasm of colon
0.665 0.335 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.664 0.336 0.000
E66.1 Drug-induced obesity
0.664 0.336 0.000
E66.0 Obesity due to excess calories
0.664 0.336 0.000
M50-M54 Other dorsopathies
0.664 0.336 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.664 0.336 0.000
S52.6 Fracture of lower end of both ulna and radius
0.663 0.337 0.000
K65-K67 Diseases of peritoneum
0.662 0.337 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.660 0.339 0.000
Q60-Q64 Congenital malformations of the urinary system
0.660 0.340 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.659 0.341 0.000
E00 Congenital iodine-deficiency syndrome
0.659 0.341 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.659 0.341 0.000
S82.8 Fractures of other parts of lower leg
0.659 0.341 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.658 0.342 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.658 0.342 0.000
C21 Malignant neoplasm of anus and anal canal
0.658 0.342 0.000
C17 Malignant neoplasm of small intestine
0.658 0.342 0.000
C23 Malignant neoplasm of gallbladder
0.658 0.342 0.000
M15 Polyarthrosis
0.657 0.343 0.000
I20.9 Angina pectoris, unspecified
0.656 0.344 0.000
R06.8 Other and unspecified abnormalities of breathing
0.656 0.344 0.000
K38 Other diseases of appendix
0.655 0.345 0.000
N60.8 Other benign mammary dysplasias
0.654 0.346 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.653 0.347 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.652 0.348 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.652 0.348 0.000
I60-I69 Cerebrovascular diseases
0.651 0.349 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.651 0.349 0.000
I27.0 Primary pulmonary hypertension
0.651 0.349 0.000
M19.8 Other specified arthrosis
0.650 0.350 0.000
M19.2 Other secondary arthrosis
0.650 0.350 0.000
S81 Open wound of lower leg
0.649 0.351 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.649 0.351 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.649 0.351 0.000
R04.1 Haemorrhage from throat
0.649 0.351 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.647 0.352 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.647 0.352 0.000
K14.8 Other diseases of tongue
0.647 0.353 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.647 0.353 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.646 0.353 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.646 0.353 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.646 0.353 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.646 0.353 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.646 0.353 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.646 0.354 0.000
N95.2 Postmenopausal atrophic vaginitis
0.646 0.354 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.645 0.354 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.645 0.355 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.645 0.355 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.645 0.355 0.000
D00-D09 In situ neoplasms
0.645 0.355 0.000
K85 Acute pancreatitis
0.644 0.356 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.644 0.356 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.644 0.356 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.644 0.356 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.644 0.356 0.000
R90.0 Intracranial space-occupying lesion
0.644 0.356 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.644 0.356 0.000
S60 Superficial injury of wrist and hand
0.643 0.356 0.000
D80-D89 Certain disorders involving the immune mechanism
0.643 0.356 0.000
S52.0 Fracture of upper end of ulna
0.643 0.356 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.643 0.357 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.643 0.357 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.642 0.358 0.000
S82.3 Fracture of lower end of tibia
0.642 0.358 0.000
A49 Bacterial infection of unspecified site
0.642 0.358 0.000
M89 Other disorders of bone
0.641 0.358 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.641 0.359 0.000
L90 Atrophic disorders of skin
0.640 0.360 0.000
E03 Other hypothyroidism
0.640 0.360 0.000
S27.0 Traumatic pneumothorax
0.640 0.360 0.000
S06 Intracranial injury
0.639 0.361 0.000
E07.9 Disorder of thyroid, unspecified
0.638 0.362 0.000
I28 Other diseases of pulmonary vessels
0.638 0.362 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.638 0.362 0.000
Y52 Agents primarily affecting the cardiovascular system
0.637 0.363 0.000
B34 Viral infection of unspecified site
0.637 0.363 0.000
E78.8 Other disorders of lipoprotein metabolism
0.636 0.364 0.000
E78.6 Lipoprotein deficiency
0.636 0.364 0.000
E78.4 Other hyperlipidaemia
0.636 0.364 0.000
E78.3 Hyperchylomicronaemia
0.636 0.364 0.000
E78.2 Mixed hyperlipidaemia
0.636 0.364 0.000
E78.1 Pure hyperglyceridaemia
0.636 0.364 0.000
S59 Other and unspecified injuries of forearm
0.636 0.364 0.000
S58 Traumatic amputation of forearm
0.636 0.364 0.000
S57 Crushing injury of forearm
0.636 0.364 0.000
S56 Injury of muscle and tendon at forearm level
0.636 0.364 0.000
S55 Injury of blood vessels at forearm level
0.636 0.364 0.000
S54 Injury of nerves at forearm level
0.636 0.364 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.636 0.364 0.000
S51 Open wound of forearm
0.636 0.364 0.000
S50 Superficial injury of forearm
0.636 0.364 0.000
B19 Unspecified viral hepatitis
0.636 0.364 0.000
B16 Acute hepatitis B
0.636 0.364 0.000
B15 Acute hepatitis A
0.636 0.364 0.000
N63 Unspecified lump in breast
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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