TreeWAS – Variant ID: rs79733525

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter V Mental and behavioural disorders	0.998	0.002
F30-F39 Mood [affective] disorders	0.998	0.002
Chapter IX Diseases of the circulatory system	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.997	0.003
F32 Depressive episode	0.997	0.003
I60-I69 Cerebrovascular diseases	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
J09-J18 Influenza and pneumonia	0.994	0.006
T36-T50 Poisoning by drugs, medicaments and biological substances	0.993	0.007
Chapter XI Diseases of the digestive system	0.993	0.007
F32.9 Depressive episode, unspecified	0.991	0.009
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.990	0.010
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.989	0.011
J18 Pneumonia, organism unspecified	0.984	0.016
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.978	0.022
J44 Other chronic obstructive pulmonary disease	0.977	0.023
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.975	0.025
K04 Diseases of pulp and periapical tissues	0.971	0.029
K70-K77 Diseases of liver	0.965	0.035
Chapter II Neoplasms	0.963	0.037
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.961	0.039
I65.2 Occlusion and stenosis of carotid artery	0.960	0.040
J18.1 Lobar pneumonia, unspecified	0.956	0.044
R30-R39 Symptoms and signs involving the urinary system	0.955	0.045
I64 Stroke, not specified as haemorrhage or infarction	0.950	0.050
J20-J22 Other acute lower respiratory infections	0.946	0.054
R39 Other symptoms and signs involving the urinary system	0.945	0.055
M45-M49 Spondylopathies	0.945	0.055
Chapter XX External causes of morbidity and mortality	0.942	0.058
T39.1 4-Aminophenol derivatives	0.941	0.059
I10-I15 Hypertensive diseases	0.940	0.060
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.937	0.063
C15-C26 Malignant neoplasms of digestive organs	0.933	0.067
M05-M14 Inflammatory polyarthropathies	0.931	0.069
J43 Emphysema	0.929	0.071
K04.6 Periapical abscess with sinus	0.927	0.073
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.924	0.076
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.924	0.076
R79 Other abnormal findings of blood chemistry	0.917	0.083
Chapter XV Pregnancy, childbirth and the puerperium	0.917	0.083
Chapter XIV Diseases of the genitourinary system	0.916	0.084
I69 Sequelae of cerebrovascular disease	0.915	0.085
I70-I79 Diseases of arteries, arterioles and capillaries	0.910	0.090
J44.9 Chronic obstructive pulmonary disease, unspecified	0.908	0.092
J22 Unspecified acute lower respiratory infection	0.908	0.092
D10-D36 Benign neoplasms	0.904	0.096
N30-N39 Other diseases of urinary system	0.899	0.101
C18 Malignant neoplasm of colon	0.891	0.109
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.891	0.109
K76 Other diseases of liver	0.889	0.111
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.888	0.112
I10 Essential (primary) hypertension	0.886	0.114
F32.0 Mild depressive episode	0.884	0.116
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.884	0.116
J43.9 Emphysema, unspecified	0.880	0.120
N10-N16 Renal tubulo-interstitial diseases	0.875	0.125
R91 Abnormal findings on diagnostic imaging of lung	0.874	0.126
F31 Bipolar affective disorder	0.867	0.133
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.865	0.135
Chapter VI Diseases of the nervous system	0.865	0.135
O20-O29 Other maternal disorders predominantly related to pregnancy	0.863	0.137
D00-D09 In situ neoplasms	0.863	0.137
K08 Other disorders of teeth and supporting structures	0.861	0.138
J18.9 Pneumonia, unspecified	0.861	0.139
M47 Spondylosis	0.860	0.140
R47-R49 Symptoms and signs involving speech and voice	0.859	0.141
F32.3 Severe depressive episode with psychotic symptoms	0.857	0.143
J13 Pneumonia due to Streptococcus pneumoniae	0.856	0.144
K05 Gingivitis and periodontal diseases	0.856	0.144
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.855	0.145
M50-M54 Other dorsopathies	0.850	0.150
Chapter XII Diseases of the skin and subcutaneous tissue	0.845	0.155
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.844	0.156
J47 Bronchiectasis	0.843	0.157
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.842	0.158
K70 Alcoholic liver disease	0.840	0.160
N32 Other disorders of bladder	0.840	0.160
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.840	0.160
K04.5 Chronic apical periodontitis	0.837	0.163
R35 Polyuria	0.831	0.169
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.829	0.171
F32.2 Severe depressive episode without psychotic symptoms	0.827	0.173
D23 Other benign neoplasms of skin	0.826	0.174
R79.9 Abnormal finding of blood chemistry, unspecified	0.825	0.175
C18.9 Colon, unspecified	0.823	0.177
R41 Other symptoms and signs involving cognitive functions and awareness	0.819	0.181
T39.0 Salicylates	0.816	0.184
I74 Arterial embolism and thrombosis	0.814	0.186
K74 Fibrosis and cirrhosis of liver	0.814	0.186
R79.8 Other specified abnormal findings of blood chemistry	0.814	0.186
M06 Other rheumatoid arthritis	0.813	0.187
J46 Status asthmaticus	0.813	0.187
F40-F48 Neurotic, stress-related and somatoform disorders	0.812	0.187
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.812	0.188
K10 Other diseases of jaws	0.811	0.189
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.808	0.192
J18.0 Bronchopneumonia, unspecified	0.808	0.192
J42 Unspecified chronic bronchitis	0.808	0.192
Chapter IV Endocrine, nutritional and metabolic diseases	0.807	0.193
I62 Other nontraumatic intracranial haemorrhage	0.804	0.196
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.803	0.197
N32.8 Other specified disorders of bladder	0.803	0.197
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.802	0.197
M80-M85 Disorders of bone density and structure	0.801	0.199
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.798	0.202
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.794	0.206
M47.8 Other spondylosis	0.793	0.207
K01 Embedded and impacted teeth	0.792	0.208
N30 Cystitis	0.791	0.209
R47 Speech disturbances, not elsewhere classified	0.789	0.211
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.789	0.211
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.788	0.212
T43.2 Other and unspecified antidepressants	0.788	0.212
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.786	0.214
D24 Benign neoplasm of breast	0.784	0.216
M07 Psoriatic and enteropathic arthropathies	0.783	0.217
J40 Bronchitis, not specified as acute or chronic	0.783	0.217
I05-I09 Chronic rheumatic heart diseases	0.779	0.220
D37-D48 Neoplasms of uncertain or unknown behaviour	0.779	0.221
K86 Other diseases of pancreas	0.778	0.222
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.778	0.222
C18.7 Sigmoid colon	0.777	0.223
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.776	0.224
S90-S99 Injuries to the ankle and foot	0.776	0.224
F80-F89 Disorders of psychological development	0.775	0.225
K02 Dental caries	0.775	0.225
O26 Maternal care for other conditions predominantly related to pregnancy	0.774	0.226
R20 Disturbances of skin sensation	0.774	0.226
R26 Abnormalities of gait and mobility	0.773	0.227
J30-J39 Other diseases of upper respiratory tract	0.773	0.227
K04.8 Radicular cyst	0.773	0.227
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.773	0.227
R72 Abnormality of white blood cells, not elsewhere classified	0.773	0.227
C19 Malignant neoplasm of rectosigmoid junction	0.771	0.229
C15 Malignant neoplasm of oesophagus	0.769	0.230
J10 Influenza due to identified influenza virus	0.768	0.232
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.768	0.232
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.767	0.233
T79-T79 Certain early complications of trauma	0.767	0.233
G90-G99 Other disorders of the nervous system	0.765	0.235
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.765	0.235
M45 Ankylosing spondylitis	0.764	0.236
N10 Acute tubulo-interstitial nephritis	0.764	0.236
K50-K52 Noninfective enteritis and colitis	0.764	0.236
M00-M03 Infectious arthropathies	0.764	0.236
M05 Seropositive rheumatoid arthritis	0.763	0.237
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.762	0.238
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.761	0.239
M46 Other inflammatory spondylopathies	0.761	0.239
K05.3 Chronic periodontitis	0.760	0.240
E10-E14 Diabetes mellitus	0.759	0.241
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.758	0.242
R40 Somnolence, stupor and coma	0.758	0.242
W00-W19 Falls	0.757	0.243
R76 Other abnormal immunological findings in serum	0.757	0.243
X60-X84 Intentional self-harm	0.756	0.244
V10-V19 Pedal cyclist injured in transport accident	0.755	0.245
F31.0 Bipolar affective disorder, current episode hypomanic	0.754	0.246
M50 Cervical disk disorders	0.753	0.247
K76.6 Portal hypertension	0.751	0.249
M14 Arthropathies in other diseases classified elsewhere	0.751	0.249
M86-M90 Other osteopathies	0.751	0.249
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.749	0.251
M91-M94 Chondropathies	0.749	0.251
R45 Symptoms and signs involving emotional state	0.747	0.253
J60-J70 Lung diseases due to external agents	0.747	0.253
D18 Haemangioma and lymphangioma, any site	0.746	0.254
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.745	0.254
D27 Benign neoplasm of ovary	0.744	0.256
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.740	0.260
I12 Hypertensive renal disease	0.739	0.261
I69.0 Sequelae of subarachnoid haemorrhage	0.738	0.262
T42.4 Benzodiazepines	0.736	0.264
K14 Diseases of tongue	0.735	0.265
D17 Benign lipomatous neoplasm	0.734	0.266
K08.8 Other specified disorders of teeth and supporting structures	0.732	0.268
T15-T19 Effects of foreign body entering through natural orifice	0.732	0.268
D26 Other benign neoplasms of uterus	0.730	0.269
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.729	0.271
D23.1 Skin of eyelid, including canthus	0.729	0.271
M48 Other spondylopathies	0.728	0.272
R47.8 Other and unspecified speech disturbances	0.727	0.273
K12 Stomatitis and related lesions	0.727	0.273
F43 Reaction to severe stress, and adjustment disorders	0.726	0.274
L40-L45 Papulosquamous disorders	0.725	0.274
K70.3 Alcoholic cirrhosis of liver	0.725	0.275
R20.8 Other and unspecified disturbances of skin sensation	0.723	0.277
O80-O84 Delivery	0.723	0.277
Chapter XXII Codes for special purposes	0.722	0.278
D09 Carcinoma in situ of other and unspecified sites	0.722	0.278
I71 Aortic aneurysm and dissection	0.721	0.279
M06.9 Rheumatoid arthritis, unspecified	0.721	0.279
K35-K38 Diseases of appendix	0.719	0.281
E11 Non-insulin-dependent diabetes mellitus	0.719	0.281
I63 Cerebral infarction	0.718	0.282
K76.0 Fatty (change of) liver, not elsewhere classified	0.718	0.282
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.718	0.282
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
F60-F69 Disorders of adult personality and behaviour	0.716	0.284
L20-L30 Dermatitis and eczema	0.716	0.284
F38 Other mood [affective] disorders	0.715	0.285
F34 Persistent mood [affective] disorders	0.715	0.285
F30 Manic episode	0.715	0.285
F39 Unspecified mood [affective] disorder	0.715	0.285
I00-I02 Acute rheumatic fever	0.715	0.285
J41 Simple and mucopurulent chronic bronchitis	0.715	0.285
F32.8 Other depressive episodes	0.715	0.285
I68 Cerebrovascular disorders in diseases classified elsewhere	0.714	0.286
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.714	0.286
R39.1 Other difficulties with micturition	0.713	0.287
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
J17 Pneumonia in diseases classified elsewhere	0.713	0.287
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.713	0.287
J15 Bacterial pneumonia, not elsewhere classified	0.713	0.287
J12 Viral pneumonia, not elsewhere classified	0.713	0.287
J11 Influenza, virus not identified	0.713	0.287
J14 Pneumonia due to Haemophilus influenzae	0.713	0.287
J09 Influenza due to certain identified influenza virus	0.713	0.287
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.713	0.287
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.712	0.288
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.712	0.288
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.712	0.288
T46 Poisoning by agents primarily affecting the cardiovascular system	0.712	0.288
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.712	0.288
T41 Poisoning by anaesthetics and therapeutic gases	0.712	0.288
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.712	0.288
T36 Poisoning by systemic antibiotics	0.712	0.288
R30 Pain associated with micturition	0.712	0.288
I72 Other aneurysm	0.711	0.288
N31.8 Other neuromuscular dysfunction of bladder	0.711	0.289
D07 Carcinoma in situ of other and unspecified genital organs	0.711	0.289
L57 Skin changes due to chronic exposure to nonionising radiation	0.711	0.289
J80-J84 Other respiratory diseases principally affecting the interstitium	0.711	0.289
I74.5 Embolism and thrombosis of iliac artery	0.710	0.290
N36 Other disorders of urethra	0.710	0.290
K09 Cysts of oral region, not elsewhere classified	0.709	0.290
K06 Other disorders of gingiva and edentulous alveolar ridge	0.709	0.290
K03 Other diseases of hard tissues of teeth	0.709	0.290
K00 Disorders of tooth development and eruption	0.709	0.290
D23.3 Skin of other and unspecified parts of face	0.709	0.291
M60-M63 Disorders of muscles	0.709	0.291
S80-S89 Injuries to the knee and lower leg	0.708	0.292
C26 Malignant neoplasm of other and ill-defined digestive organs	0.707	0.292
S70-S79 Injuries to the hip and thigh	0.705	0.295
J18.8 Other pneumonia, organism unspecified	0.705	0.295
J18.2 Hypostatic pneumonia, unspecified	0.705	0.295
R44 Other symptoms and signs involving general sensations and perceptions	0.704	0.296
O85-O92 Complications predominantly related to the puerperium	0.704	0.296
K76.9 Liver disease, unspecified	0.704	0.296
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.703	0.297
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.703	0.297
O94-O99 Other obstetric conditions, not elsewhere classified	0.702	0.298
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.702	0.298
M47.2 Other spondylosis with radiculopathy	0.702	0.298
D34 Benign neoplasm of thyroid gland	0.702	0.298
I69.3 Sequelae of cerebral infarction	0.701	0.298
G80-G83 Cerebral palsy and other paralytic syndromes	0.701	0.299
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.701	0.299
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.701	0.299
T39.4 Antirheumatics, not elsewhere classified	0.701	0.299
T39.2 Pyrazolone derivatives	0.701	0.299
R26.8 Other and unspecified abnormalities of gait and mobility	0.701	0.299
F99-F99 Unspecified mental disorder	0.701	0.299
R79.0 Abnormal level of blood mineral	0.700	0.300
D29 Benign neoplasm of male genital organs	0.700	0.300
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.699	0.301
I65.8 Occlusion and stenosis of other precerebral artery	0.699	0.301
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.699	0.301
I65.1 Occlusion and stenosis of basilar artery	0.699	0.301
I65.0 Occlusion and stenosis of vertebral artery	0.699	0.301
M47.80 Other spondylosis (Multiple sites in spine)	0.698	0.302
J36 Peritonsillar abscess	0.698	0.302
M47.82 Other spondylosis (Cervical region)	0.698	0.302
O21 Excessive vomiting in pregnancy	0.697	0.303
K04.4 Acute apical periodontitis of pulpal origin	0.696	0.304
K04.3 Abnormal hard tissue formation in pulp	0.696	0.304
K04.2 Pulp degeneration	0.696	0.304
K04.1 Necrosis of pulp	0.696	0.304
K04.0 Pulpitis	0.696	0.304
O20 Haemorrhage in early pregnancy	0.696	0.304
J95-J99 Other diseases of the respiratory system	0.696	0.304
I60 Subarachnoid haemorrhage	0.695	0.305
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.695	0.305
Y95 Nosocomial condition	0.695	0.305
K75 Other inflammatory liver diseases	0.694	0.306
K74.6 Other and unspecified cirrhosis of liver	0.694	0.306
W20-W49 Exposure to inanimate mechanical forces	0.692	0.308
K77 Liver disorders in diseases classified elsewhere	0.692	0.308
K73 Chronic hepatitis, not elsewhere classified	0.692	0.308
K71 Toxic liver disease	0.692	0.308
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.691	0.308
M40-M43 Deforming dorsopathies	0.691	0.308
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.690	0.310
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.690	0.310
C40-C41 Malignant neoplasms of bone and articular cartilage	0.690	0.310
K65-K67 Diseases of peritoneum	0.690	0.310
R78 Findings of drugs and other substances, not normally found in blood	0.689	0.311
R77 Other abnormalities of plasma proteins	0.689	0.311
R74 Abnormal serum enzyme levels	0.689	0.311
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.689	0.311
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.689	0.311
R71 Abnormality of red blood cells	0.689	0.311
D10 Benign neoplasm of mouth and pharynx	0.688	0.312
F33 Recurrent depressive disorder	0.688	0.312
I70 Atherosclerosis	0.687	0.313
C18.3 Hepatic flexure	0.687	0.313
G50-G59 Nerve, nerve root and plexus disorders	0.687	0.313
N70-N77 Inflammatory diseases of female pelvic organs	0.686	0.314
D03 Melanoma in situ	0.686	0.314
K76.8 Other specified diseases of liver	0.686	0.314
R32 Unspecified urinary incontinence	0.686	0.314
S40-S49 Injuries to the shoulder and upper arm	0.685	0.315
R23 Other skin changes	0.685	0.315
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.685	0.315
N99-N99 Other disorders of the genitourinary system	0.685	0.315
R36 Urethral discharge	0.685	0.315
R34 Anuria and oliguria	0.685	0.315
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.685	0.315
D17.9 Benign lipomatous neoplasm, unspecified	0.683	0.317
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.682	0.318
K72 Hepatic failure, not elsewhere classified	0.682	0.318
K86.1 Other chronic pancreatitis	0.680	0.320
K11 Diseases of salivary glands	0.679	0.321
G40-G47 Episodic and paroxysmal disorders	0.679	0.321
J21 Acute bronchiolitis	0.678	0.322
J20 Acute bronchitis	0.678	0.322
R39.2 Extrarenal uraemia	0.677	0.322
R39.0 Extravasation of urine	0.677	0.322
M07.3 Other psoriatic arthropathies	0.677	0.323
M49 Spondylopathies in diseases classified elsewhere	0.677	0.323
R41.3 Other amnesia	0.677	0.323
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.676	0.324
Y35-Y36 Legal intervention and operations of war	0.676	0.324
Y10-Y34 Event of undetermined intent	0.676	0.324
Y00-Y09 Assault	0.676	0.324
X85-X99 Assault	0.676	0.324
X58-X59 Accidental exposure to other and unspecified factors	0.676	0.324
X50-X57 Overexertion, travel and privation	0.676	0.324
X40-X49 Accidental poisoning by and exposure to noxious substances	0.676	0.324
X30-X39 Exposure to forces of nature	0.676	0.324
X20-X29 Contact with venomous animals and plants	0.676	0.324
X10-X19 Contact with heat and hot substances	0.676	0.324
X00-X09 Exposure to smoke, fire and flames	0.676	0.324
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.676	0.324
W75-W84 Other accidental threats to breathing	0.676	0.324
W65-W74 Accidental drowning and submersion	0.676	0.324
W50-W64 Exposure to animate mechanical forces	0.676	0.324
V98-V99 Other and unspecified transport accidents	0.676	0.324
V95-V97 Air and space transport accidents	0.676	0.324
V90-V94 Water transport accidents	0.676	0.324
V80-V89 Other land transport accidents	0.676	0.324
V70-V79 Bus occupant injured in transport accident	0.676	0.324
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.676	0.324
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.676	0.324
V40-V49 Car occupant injured in transport accident	0.676	0.324
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.676	0.324
V01-V09 Pedestrian injured in transport accident	0.676	0.324
M10 Gout	0.675	0.325
I15 Secondary hypertension	0.674	0.326
I13 Hypertensive heart and renal disease	0.674	0.326
I11 Hypertensive heart disease	0.674	0.326
M70-M79 Other soft tissue disorders	0.674	0.326
K07 Dentofacial anomalies [including malocclusion]	0.673	0.327
M80 Osteoporosis with pathological fracture	0.673	0.327
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.673	0.327
L57.0 Actinic keratosis	0.672	0.328
C16 Malignant neoplasm of stomach	0.672	0.328
N30.2 Other chronic cystitis	0.671	0.328
S20-S29 Injuries to the thorax	0.671	0.329
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.670	0.330
N30.9 Cystitis, unspecified	0.670	0.330
V20-V29 Motorcycle rider injured in transport accident	0.669	0.331
C21 Malignant neoplasm of anus and anal canal	0.669	0.331
C17 Malignant neoplasm of small intestine	0.669	0.331
C23 Malignant neoplasm of gallbladder	0.669	0.331
G99 Other disorders of nervous system in diseases classified elsewhere	0.668	0.332
M12 Other specific arthropathies	0.668	0.332
M11 Other crystal arthropathies	0.668	0.332
M09 Juvenile arthritis in diseases classified elsewhere	0.668	0.332
M08 Juvenile arthritis	0.668	0.332
F32.1 Moderate depressive episode	0.667	0.332
E11.9 Without complications	0.667	0.333
T50.9 Other and unspecified drugs, medicaments and biological substances	0.667	0.333
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.667	0.333
Y45.0 Opioids and related analgesics	0.666	0.334
J43.8 Other emphysema	0.666	0.334
J43.2 Centrilobular emphysema	0.666	0.334
J43.1 Panlobular emphysema	0.666	0.334
J43.0 MacLeod's syndrome	0.666	0.334
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.666	0.334
Y57 Other and unspecified drugs and medicaments	0.665	0.335
D05 Carcinoma in situ of breast	0.665	0.335
I73 Other peripheral vascular diseases	0.665	0.335
Y44 Agents primarily affecting blood constituents	0.665	0.335
I95-I99 Other and unspecified disorders of the circulatory system	0.664	0.335
Chapter VIII Diseases of the ear and mastoid process	0.664	0.335
D32 Benign neoplasm of meninges	0.664	0.336
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.664	0.336
O26.8 Other specified pregnancy-related conditions	0.664	0.336
F31.9 Bipolar affective disorder, unspecified	0.663	0.337
R46 Symptoms and signs involving appearance and behaviour	0.662	0.338
R43 Disturbances of smell and taste	0.662	0.338
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.661	0.339
D14 Benign neoplasm of middle ear and respiratory system	0.660	0.339
K70.1 Alcoholic hepatitis	0.659	0.341
K50 Crohn's disease [regional enteritis]	0.659	0.341
C60-C63 Malignant neoplasms of male genital organs	0.658	0.342
D23.6 Skin of upper limb, including shoulder	0.658	0.342
N11 Chronic tubulo-interstitial nephritis	0.657	0.343
T43.5 Other and unspecified antipsychotics and neuroleptics	0.657	0.343
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.656	0.344
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.656	0.344
I69.1 Sequelae of intracerebral haemorrhage	0.656	0.344
K04.7 Periapical abscess without sinus	0.656	0.344
R41.0 Disorientation, unspecified	0.656	0.344
T43.3 Phenothiazine antipsychotics and neuroleptics	0.655	0.345
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.654	0.346
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.653	0.347
Q50-Q56 Congenital malformations of genital organs	0.652	0.348
Y40 Systemic antibiotics	0.652	0.348
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.650	0.349
O26.9 Pregnancy-related condition, unspecified	0.649	0.351
D31 Benign neoplasm of eye and adnexa	0.648	0.352
D30 Benign neoplasm of urinary organs	0.648	0.352
D28 Benign neoplasm of other and unspecified female genital organs	0.648	0.352
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.648	0.352
D19 Benign neoplasm of mesothelial tissue	0.648	0.352
D16 Benign neoplasm of bone and articular cartilage	0.648	0.352
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.648	0.352
R27 Other lack of coordination	0.647	0.352
C18.4 Transverse colon	0.647	0.353
I08 Multiple valve diseases	0.647	0.353
R50-R69 General symptoms and signs	0.646	0.354
F43.2 Adjustment disorders	0.645	0.355
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.644	0.355
N37 Urethral disorders in diseases classified elsewhere	0.644	0.356
N34 Urethritis and urethral syndrome	0.644	0.356
N33 Bladder disorders in diseases classified elsewhere	0.644	0.356
J30 Vasomotor and allergic rhinitis	0.644	0.356
M54 Dorsalgia	0.644	0.356
R04 Haemorrhage from respiratory passages	0.644	0.356
N13 Obstructive and reflux uropathy	0.643	0.357
Y60-Y69 Misadventures to patients during surgical and medical care	0.643	0.357
M05.9 Seropositive rheumatoid arthritis, unspecified	0.643	0.357
R63 Symptoms and signs concerning food and fluid intake	0.643	0.357
F00-F09 Organic, including symptomatic, mental disorders	0.642	0.358
I67 Other cerebrovascular diseases	0.642	0.358
K86.2 Cyst of pancreas	0.642	0.358
K10.8 Other specified diseases of jaws	0.642	0.358
Chapter I Certain infectious and parasitic diseases	0.641	0.359
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.641	0.359
T51 Toxic effect of alcohol	0.641	0.359
R90 Abnormal findings on diagnostic imaging of central nervous system	0.640	0.360
M50.3 Other cervical disk degeneration	0.640	0.360
R45.8 Other symptoms and signs involving emotional state	0.639	0.361
C18.8 Overlapping lesion of colon	0.639	0.361
C18.5 Splenic flexure	0.639	0.361
C18.1 Appendix	0.639	0.361
K10.2 Inflammatory conditions of jaws	0.638	0.362
E13 Other specified diabetes mellitus	0.638	0.362
R63.4 Abnormal weight loss	0.638	0.362
O24 Diabetes mellitus in pregnancy	0.637	0.363
T43.0 Tricyclic and tetracyclic antidepressants	0.637	0.363
C18.2 Ascending colon	0.637	0.363
K76.7 Hepatorenal syndrome	0.637	0.363
K76.5 Hepatic veno-occlusive disease	0.637	0.363
K76.4 Peliosis hepatis	0.637	0.363
K76.3 Infarction of liver	0.637	0.363
K76.2 Central haemorrhagic necrosis of liver	0.637	0.363
K76.1 Chronic passive congestion of liver	0.637	0.363
T40.2 Other opioids	0.637	0.363
R92 Abnormal findings on diagnostic imaging of breast	0.637	0.363
R04.2 Haemoptysis	0.637	0.363
N25-N29 Other disorders of kidney and ureter	0.637	0.363
M65-M68 Disorders of synovium and tendon	0.637	0.363
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.636	0.364
R47.1 Dysarthria and anarthria	0.636	0.364
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.636	0.364
N32.0 Bladder-neck obstruction	0.635	0.365
D21 Other benign neoplasms of connective and other soft tissue	0.635	0.365
T43.9 Psychotropic drug, unspecified	0.634	0.366
T43.8 Other psychotropic drugs, not elsewhere classified	0.634	0.366
T43.6 Psychostimulants with abuse potential	0.634	0.366
T43.4 Butyrophenone and thioxanthene neuroleptics	0.634	0.366
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.634	0.366
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.634	0.366
R22.0 Localised swelling, mass and lump, head	0.634	0.366
K82 Other diseases of gallbladder	0.634	0.366

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations