TreeWAS – Variant ID: rs79758531

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
Z88.0 Personal history of allergy to penicillin	0.996	0.004	0.000
S60-S69 Injuries to the wrist and hand	0.988	0.012	0.000
Chapter V Mental and behavioural disorders	0.988	0.012	0.000
M20-M25 Other joint disorders	0.988	0.012	0.000
Chapter IX Diseases of the circulatory system	0.987	0.013	0.000
M05-M14 Inflammatory polyarthropathies	0.986	0.014	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.986	0.014	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.983	0.017	0.000
Chapter I Certain infectious and parasitic diseases	0.982	0.018	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.981	0.019	0.000
M13 Other arthritis	0.976	0.024	0.000
M70-M79 Other soft tissue disorders	0.972	0.028	0.000
M13.9 Arthritis, unspecified	0.969	0.031	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.969	0.031	0.000
I84 Haemorrhoids	0.963	0.037	0.000
S00-S09 Injuries to the head	0.959	0.041	0.000
Chapter II Neoplasms	0.958	0.042	0.000
R02 Gangrene, not elsewhere classified	0.952	0.048	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.951	0.049	0.000
M25 Other joint disorders, not elsewhere classified	0.947	0.053	0.000
F30-F39 Mood [affective] disorders	0.942	0.058	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.935	0.065	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.935	0.065	0.000
M75 Shoulder lesions	0.927	0.073	0.000
E70-E90 Metabolic disorders	0.927	0.073	0.000
I84.1 Internal haemorrhoids with other complications	0.926	0.074	0.000
A30-A49 Other bacterial diseases	0.921	0.079	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.919	0.081	0.000
M20 Acquired deformities of fingers and toes	0.917	0.083	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.917	0.083	0.000
B95-B98 Bacterial, viral and other infectious agents	0.915	0.085	0.000
M13.94 Arthritis, unspecified (Hand)	0.914	0.086	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.910	0.090	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.909	0.091	0.000
Chapter XIV Diseases of the genitourinary system	0.908	0.092	0.000
M25.7 Osteophyte	0.904	0.096	0.000
R05 Cough	0.902	0.098	0.000
Chapter VI Diseases of the nervous system	0.897	0.103	0.000
M20.5 Other deformities of toe(s) (acquired)	0.895	0.105	0.000
M75.4 Impingement syndrome of shoulder	0.895	0.105	0.000
E89.0 Postprocedural hypothyroidism	0.890	0.110	0.000
N10-N16 Renal tubulo-interstitial diseases	0.888	0.112	0.000
C15-C26 Malignant neoplasms of digestive organs	0.885	0.115	0.000
R01 Cardiac murmurs and other cardiac sounds	0.880	0.120	0.000
E65-E68 Obesity and other hyperalimentation	0.878	0.122	0.000
D45 Polycythaemia vera	0.878	0.122	0.000
R26 Abnormalities of gait and mobility	0.877	0.123	0.000
S06 Intracranial injury	0.876	0.124	0.000
S64 Injury of nerves at wrist and hand level	0.876	0.124	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.875	0.125	0.000
S70-S79 Injuries to the hip and thigh	0.872	0.128	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.867	0.133	0.000
S01 Open wound of head	0.866	0.134	0.000
I81 Portal vein thrombosis	0.865	0.135	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.863	0.137	0.000
S80-S89 Injuries to the knee and lower leg	0.862	0.138	0.000
F33 Recurrent depressive disorder	0.862	0.138	0.000
A41 Other septicaemia	0.860	0.140	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.858	0.142	0.000
I26 Pulmonary embolism	0.857	0.143	0.000
R04 Haemorrhage from respiratory passages	0.855	0.145	0.000
M13.98 Arthritis, unspecified (Other)	0.854	0.146	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.853	0.147	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.853	0.147	0.000
Chapter XXII Codes for special purposes	0.852	0.148	0.000
G20-G26 Extrapyramidal and movement disorders	0.851	0.149	0.000
S02 Fracture of skull and facial bones	0.850	0.150	0.000
N13 Obstructive and reflux uropathy	0.849	0.151	0.000
M05 Seropositive rheumatoid arthritis	0.848	0.152	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.846	0.154	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.846	0.154	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.844	0.156	0.000
F31 Bipolar affective disorder	0.842	0.158	0.000
I85 Oesophageal varices	0.841	0.159	0.000
S61 Open wound of wrist and hand	0.839	0.161	0.000
D00-D09 In situ neoplasms	0.839	0.161	0.000
M80-M85 Disorders of bone density and structure	0.839	0.161	0.000
I86 Varicose veins of other sites	0.836	0.164	0.000
I84.9 Unspecified haemorrhoids without complication	0.832	0.168	0.000
T79-T79 Certain early complications of trauma	0.830	0.170	0.000
I84.5 External haemorrhoids without complication	0.830	0.170	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.828	0.172	0.000
Chapter XXI Factors influencing health status and contact with health services	0.827	0.173	0.000
S40-S49 Injuries to the shoulder and upper arm	0.823	0.177	0.000
G20 Parkinson's disease	0.822	0.178	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.820	0.180	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.814	0.186	0.000
E66 Obesity	0.814	0.186	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.814	0.186	0.000
R06 Abnormalities of breathing	0.813	0.187	0.000
B15-B19 Viral hepatitis	0.811	0.189	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.811	0.189	0.000
N60-N64 Disorders of breast	0.809	0.191	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.807	0.193	0.000
R01.1 Cardiac murmur, unspecified	0.805	0.195	0.000
N13.3 Other and unspecified hydronephrosis	0.805	0.195	0.000
E20-E35 Disorders of other endocrine glands	0.804	0.196	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.803	0.197	0.000
C18 Malignant neoplasm of colon	0.803	0.197	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.803	0.197	0.000
I84.6 Residual haemorrhoidal skin tags	0.802	0.198	0.000
M25.76 Osteophyte (Lower leg)	0.801	0.199	0.000
F03 Unspecified dementia	0.800	0.200	0.000
R47-R49 Symptoms and signs involving speech and voice	0.798	0.202	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.794	0.206	0.000
F33.9 Recurrent depressive disorder, unspecified	0.792	0.208	0.000
E83 Disorders of mineral metabolism	0.791	0.209	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.790	0.210	0.000
M40-M43 Deforming dorsopathies	0.788	0.212	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.787	0.213	0.000
S06.5 Traumatic subdural haemorrhage	0.786	0.214	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.785	0.215	0.000
M91-M94 Chondropathies	0.785	0.215	0.000
M50-M54 Other dorsopathies	0.783	0.217	0.000
E86 Volume depletion	0.783	0.217	0.000
I05-I09 Chronic rheumatic heart diseases	0.781	0.219	0.000
S20-S29 Injuries to the thorax	0.779	0.221	0.000
S62 Fracture at wrist and hand level	0.779	0.221	0.000
M72 Fibroblastic disorders	0.778	0.222	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.777	0.223	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.776	0.224	0.000
M65-M68 Disorders of synovium and tendon	0.769	0.231	0.000
I84.4 External haemorrhoids with other complications	0.769	0.231	0.000
M24 Other specific joint derangements	0.768	0.232	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.766	0.234	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.763	0.236	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.760	0.239	0.000
M22 Disorders of patella	0.758	0.242	0.000
E66.9 Obesity, unspecified	0.757	0.243	0.000
S70 Superficial injury of hip and thigh	0.756	0.244	0.000
S10-S19 Injuries to the neck	0.756	0.244	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.754	0.246	0.000
F80-F89 Disorders of psychological development	0.754	0.246	0.000
M75.2 Bicipital tendinitis	0.753	0.247	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.752	0.248	0.000
S61.0 Open wound of finger(s) without damage to nail	0.752	0.248	0.000
N20-N23 Urolithiasis	0.752	0.248	0.000
C21 Malignant neoplasm of anus and anal canal	0.749	0.251	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.749	0.251	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.748	0.252	0.000
R06.5 Mouth breathing	0.747	0.253	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.747	0.253	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.747	0.253	0.000
N64 Other disorders of breast	0.747	0.253	0.000
B35-B49 Mycoses	0.746	0.254	0.000
I86.4 Gastric varices	0.746	0.254	0.000
S01.9 Open wound of head, part unspecified	0.744	0.256	0.000
E50-E64 Other nutritional deficiencies	0.743	0.257	0.000
M25.77 Osteophyte (Ankle and foot)	0.742	0.258	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.742	0.258	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.742	0.258	0.000
Chapter X Diseases of the respiratory system	0.741	0.259	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.740	0.259	0.000
E40-E46 Malnutrition	0.739	0.260	0.000
D06 Carcinoma in situ of cervix uteri	0.739	0.261	0.000
R09.1 Pleurisy	0.738	0.262	0.000
Chapter VIII Diseases of the ear and mastoid process	0.737	0.263	0.000
E89.2 Postprocedural hypoparathyroidism	0.737	0.263	0.000
M00-M03 Infectious arthropathies	0.735	0.264	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.735	0.265	0.000
R00 Abnormalities of heart beat	0.733	0.267	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.733	0.267	0.000
T66-T78 Other and unspecified effects of external causes	0.732	0.268	0.000
B25-B34 Other viral diseases	0.732	0.268	0.000
A49 Bacterial infection of unspecified site	0.732	0.268	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.730	0.270	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.729	0.271	0.000
N10 Acute tubulo-interstitial nephritis	0.729	0.271	0.000
I71 Aortic aneurysm and dissection	0.729	0.271	0.000
M86-M90 Other osteopathies	0.728	0.272	0.000
M77 Other enthesopathies	0.727	0.273	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.726	0.274	0.000
Chapter XX External causes of morbidity and mortality	0.726	0.274	0.000
F00 Dementia in Alzheimer's disease	0.725	0.275	0.000
M20.0 Deformity of finger(s)	0.725	0.275	0.000
S01.5 Open wound of lip and oral cavity	0.724	0.276	0.000
C51-C58 Malignant neoplasms of female genital organs	0.723	0.277	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.723	0.277	0.000
I84.3 External thrombosed haemorrhoids	0.723	0.277	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.722	0.278	0.000
S64.4 Injury of digital nerve of other finger	0.722	0.278	0.000
M25.71 Osteophyte (Shoulder region)	0.720	0.280	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.720	0.280	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.719	0.281	0.000
Z72 Problems related to lifestyle	0.718	0.282	0.000
R04.2 Haemoptysis	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.717	0.283	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
I82 Other venous embolism and thrombosis	0.716	0.284	0.000
M85 Other disorders of bone density and structure	0.716	0.284	0.000
M75.1 Rotator cuff syndrome	0.716	0.284	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.716	0.284	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.716	0.284	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.716	0.284	0.000
M71 Other bursopathies	0.714	0.286	0.000
M25.5 Pain in joint	0.714	0.286	0.000
D41.4 Bladder	0.714	0.286	0.000
S60 Superficial injury of wrist and hand	0.713	0.287	0.000
C01 Malignant neoplasm of base of tongue	0.713	0.287	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.709	0.291	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.709	0.291	0.000
M25.78 Osteophyte (Other)	0.709	0.291	0.000
F31.9 Bipolar affective disorder, unspecified	0.709	0.291	0.000
A80-A89 Viral infections of the central nervous system	0.708	0.292	0.000
S69 Other and unspecified injuries of wrist and hand	0.708	0.292	0.000
S67 Crushing injury of wrist and hand	0.708	0.292	0.000
S65 Injury of blood vessels at wrist and hand level	0.708	0.292	0.000
F99-F99 Unspecified mental disorder	0.708	0.292	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.708	0.292	0.000
F70-F79 Mental retardation	0.708	0.292	0.000
F60-F69 Disorders of adult personality and behaviour	0.708	0.292	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.708	0.292	0.000
M34 Systemic sclerosis	0.708	0.292	0.000
M33 Dermatopolymyositis	0.708	0.292	0.000
M32 Systemic lupus erythematosus	0.708	0.292	0.000
M30 Polyarteritis nodosa and related conditions	0.708	0.292	0.000
M21 Other acquired deformities of limbs	0.708	0.292	0.000
I00-I02 Acute rheumatic fever	0.708	0.292	0.000
M31 Other necrotising vasculopathies	0.708	0.292	0.000
G30-G32 Other degenerative diseases of the nervous system	0.707	0.292	0.000
M14 Arthropathies in other diseases classified elsewhere	0.707	0.293	0.000
M12 Other specific arthropathies	0.707	0.293	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.707	0.293	0.000
M08 Juvenile arthritis	0.707	0.293	0.000
M23 Internal derangement of knee	0.707	0.293	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.707	0.293	0.000
S01.2 Open wound of nose	0.706	0.294	0.000
M75.0 Adhesive capsulitis of shoulder	0.705	0.295	0.000
B99-B99 Other infectious diseases	0.704	0.296	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.704	0.296	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.704	0.296	0.000
B65-B83 Helminthiases	0.704	0.296	0.000
B50-B64 Protozoal diseases	0.704	0.296	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.704	0.296	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.704	0.296	0.000
A75-A79 Rickettsioses	0.704	0.296	0.000
A70-A74 Other diseases caused by chlamydiae	0.704	0.296	0.000
A65-A69 Other spirochaetal diseases	0.704	0.296	0.000
A20-A28 Certain zoonotic bacterial diseases	0.704	0.296	0.000
A15-A19 Tuberculosis	0.704	0.296	0.000
R26.0 Ataxic gait	0.704	0.296	0.000
D41.0 Kidney	0.703	0.297	0.000
I88 Nonspecific lymphadenitis	0.703	0.297	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.702	0.298	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.702	0.298	0.000
C09 Malignant neoplasm of tonsil	0.701	0.299	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.700	0.300	0.000
M13.8 Other specified arthritis	0.700	0.300	0.000
M13.1 Monoarthritis, not elsewhere classified	0.700	0.300	0.000
M13.0 Polyarthritis, unspecified	0.700	0.300	0.000
I27 Other pulmonary heart diseases	0.699	0.301	0.000
G62 Other polyneuropathies	0.699	0.301	0.000
C20 Malignant neoplasm of rectum	0.699	0.301	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.699	0.301	0.000
S02.1 Fracture of base of skull	0.698	0.301	0.000
D48.5 Skin	0.698	0.302	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.698	0.302	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.698	0.302	0.000
S64.3 Injury of digital nerve of thumb	0.698	0.302	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.698	0.302	0.000
I87 Other disorders of veins	0.697	0.302	0.000
I85.0 Oesophageal varices with bleeding	0.697	0.303	0.000
M76 Enthesopathies of lower limb, excluding foot	0.697	0.303	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.697	0.303	0.000
R47 Speech disturbances, not elsewhere classified	0.696	0.304	0.000
S02.0 Fracture of vault of skull	0.696	0.304	0.000
R27 Other lack of coordination	0.696	0.304	0.000
D46 Myelodysplastic syndromes	0.695	0.305	0.000
M13.93 Arthritis, unspecified (Forearm)	0.695	0.305	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.695	0.305	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.694	0.306	0.000
S81 Open wound of lower leg	0.694	0.306	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.694	0.306	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.693	0.307	0.000
S42 Fracture of shoulder and upper arm	0.693	0.307	0.000
R04.0 Epistaxis	0.692	0.308	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.691	0.309	0.000
I84.0 Internal thrombosed haemorrhoids	0.690	0.310	0.000
C18.4 Transverse colon	0.689	0.311	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.689	0.311	0.000
C18.7 Sigmoid colon	0.688	0.312	0.000
S08 Traumatic amputation of part of head	0.688	0.312	0.000
S07 Crushing injury of head	0.688	0.312	0.000
S05 Injury of eye and orbit	0.688	0.312	0.000
S04 Injury of cranial nerves	0.688	0.312	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.688	0.312	0.000
F43 Reaction to severe stress, and adjustment disorders	0.687	0.312	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.687	0.313	0.000
M07 Psoriatic and enteropathic arthropathies	0.687	0.313	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.687	0.313	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.687	0.313	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.686	0.314	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.685	0.315	0.000
Z74 Problems related to care-provider dependency	0.685	0.315	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.684	0.316	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.683	0.317	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.682	0.318	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.682	0.318	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.682	0.318	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.682	0.318	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.682	0.318	0.000
M20.4 Other hammer toe(s) (acquired)	0.682	0.318	0.000
F01 Vascular dementia	0.679	0.320	0.000
S71 Open wound of hip and thigh	0.679	0.321	0.000
M25.9 Joint disorder, unspecified	0.679	0.321	0.000
M25.8 Other specified joint disorders	0.679	0.321	0.000
M25.3 Other instability of joint	0.679	0.321	0.000
M25.2 Flail joint	0.679	0.321	0.000
M25.1 Fistula of joint	0.679	0.321	0.000
M25.0 Haemarthrosis	0.679	0.321	0.000
S06.2 Diffuse brain injury	0.679	0.321	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.677	0.323	0.000
F41 Other anxiety disorders	0.677	0.323	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.676	0.324	0.000
D37.7 Other digestive organs	0.676	0.324	0.000
F38 Other mood [affective] disorders	0.675	0.324	0.000
F34 Persistent mood [affective] disorders	0.675	0.324	0.000
F30 Manic episode	0.675	0.324	0.000
F39 Unspecified mood [affective] disorder	0.675	0.324	0.000
I85.9 Oesophageal varices without bleeding	0.675	0.325	0.000
C25 Malignant neoplasm of pancreas	0.675	0.325	0.000
M45-M49 Spondylopathies	0.674	0.325	0.000
J09-J18 Influenza and pneumonia	0.674	0.326	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.673	0.327	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.673	0.327	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.671	0.328	0.000
N11 Chronic tubulo-interstitial nephritis	0.671	0.329	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.671	0.329	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.671	0.329	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.671	0.329	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.671	0.329	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.671	0.329	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.671	0.329	0.000
D03 Melanoma in situ	0.670	0.330	0.000
E83.5 Disorders of calcium metabolism	0.670	0.330	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.670	0.330	0.000
Q80-Q89 Other congenital malformations	0.669	0.331	0.000
I74 Arterial embolism and thrombosis	0.668	0.332	0.000
D06.9 Cervix, unspecified	0.668	0.332	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.668	0.332	0.000
D48.1 Connective and other soft tissue	0.667	0.333	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.666	0.333	0.000
R94 Abnormal results of function studies	0.666	0.334	0.000
N64.1 Fat necrosis of breast	0.666	0.334	0.000
M11 Other crystal arthropathies	0.666	0.334	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.665	0.335	0.000
M75.8 Other shoulder lesions	0.665	0.335	0.000
M75.9 Shoulder lesion, unspecified	0.665	0.335	0.000
E85 Amyloidosis	0.665	0.335	0.000
E84 Cystic fibrosis	0.665	0.335	0.000
E79 Disorders of purine and pyrimidine metabolism	0.665	0.335	0.000
E77 Disorders of glycoprotein metabolism	0.665	0.335	0.000
E76 Disorders of glycosaminoglycan metabolism	0.665	0.335	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.665	0.335	0.000
E74 Other disorders of carbohydrate metabolism	0.665	0.335	0.000
E73 Lactose intolerance	0.665	0.335	0.000
E72 Other disorders of amino-acid metabolism	0.665	0.335	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.665	0.335	0.000
E70 Disorders of aromatic amino-acid metabolism	0.665	0.335	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.665	0.335	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.664	0.336	0.000
E88 Other metabolic disorders	0.664	0.336	0.000
S80 Superficial injury of lower leg	0.663	0.337	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.662	0.338	0.000
N25-N29 Other disorders of kidney and ureter	0.662	0.338	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.662	0.338	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.662	0.338	0.000
N62 Hypertrophy of breast	0.662	0.338	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.661	0.338	0.000
F40 Phobic anxiety disorders	0.661	0.339	0.000
D04 Carcinoma in situ of skin	0.661	0.339	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.661	0.339	0.000
D37.4 Colon	0.660	0.340	0.000
A48 Other bacterial diseases, not elsewhere classified	0.660	0.340	0.000
A44 Bartonellosis	0.660	0.340	0.000
A43 Nocardiosis	0.660	0.340	0.000
A42 Actinomycosis	0.660	0.340	0.000
A40 Streptococcal septicaemia	0.660	0.340	0.000
A39 Meningococcal infection	0.660	0.340	0.000
A37 Whooping cough	0.660	0.340	0.000
A36 Diphtheria	0.660	0.340	0.000
A32 Listeriosis	0.660	0.340	0.000
A31 Infection due to other mycobacteria	0.660	0.340	0.000
A30 Leprosy [Hansen's disease]	0.660	0.340	0.000
A46 Erysipelas	0.660	0.340	0.000
A38 Scarlet fever	0.660	0.340	0.000
A35 Other tetanus	0.660	0.340	0.000
A34 Obstetrical tetanus	0.660	0.340	0.000
A33 Tetanus neonatorum	0.660	0.340	0.000
Z22 Carrier of infectious disease	0.660	0.340	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.659	0.341	0.000
F02 Dementia in other diseases classified elsewhere	0.659	0.341	0.000
F09 Unspecified organic or symptomatic mental disorder	0.659	0.341	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.659	0.341	0.000
M84 Disorders of continuity of bone	0.659	0.341	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.659	0.341	0.000
N13.8 Other obstructive and reflux uropathy	0.659	0.341	0.000
I07 Rheumatic tricuspid valve diseases	0.658	0.342	0.000
M20.3 Other deformity of hallux (acquired)	0.657	0.343	0.000
I28 Other diseases of pulmonary vessels	0.657	0.343	0.000
E29 Testicular dysfunction	0.656	0.344	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.656	0.344	0.000
S68 Traumatic amputation of wrist and hand	0.656	0.344	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.655	0.345	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.655	0.345	0.000
M06 Other rheumatoid arthritis	0.654	0.346	0.000
F32 Depressive episode	0.653	0.347	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.653	0.347	0.000
S50-S59 Injuries to the elbow and forearm	0.652	0.347	0.001
S02.3 Fracture of orbital floor	0.652	0.348	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.652	0.348	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.652	0.348	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.652	0.348	0.000
E89.5 Postprocedural testicular hypofunction	0.652	0.348	0.000
E89.4 Postprocedural ovarian failure	0.652	0.348	0.000
E89.3 Postprocedural hypopituitarism	0.652	0.348	0.000
E89.1 Postprocedural hypoinsulinaemia	0.652	0.348	0.000
M54 Dorsalgia	0.652	0.348	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.651	0.348	0.000
S06.0 Concussion	0.651	0.349	0.000
M25.79 Osteophyte (Site unspecified)	0.648	0.352	0.000
M25.73 Osteophyte (Forearm)	0.648	0.352	0.000
M25.72 Osteophyte (Upper arm)	0.648	0.352	0.000
M25.70 Osteophyte (Multiple sites)	0.648	0.352	0.000
B17 Other acute viral hepatitis	0.648	0.352	0.000
U80 Agent resistant to penicillin and related antibiotics	0.648	0.352	0.000
S20 Superficial injury of thorax	0.647	0.353	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.647	0.353	0.000
Q60-Q64 Congenital malformations of the urinary system	0.647	0.353	0.000
M20.1 Hallux valgus (acquired)	0.647	0.353	0.000
Q50-Q56 Congenital malformations of genital organs	0.647	0.353	0.000
I73 Other peripheral vascular diseases	0.647	0.353	0.000
S90-S99 Injuries to the ankle and foot	0.646	0.354	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.646	0.354	0.000
A41.9 Septicaemia, unspecified	0.646	0.354	0.000
H60-H62 Diseases of external ear	0.645	0.355	0.000
R47.8 Other and unspecified speech disturbances	0.644	0.356	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.643	0.357	0.000
S01.0 Open wound of scalp	0.642	0.357	0.000
N13.4 Hydroureter	0.642	0.358	0.000
F41.2 Mixed anxiety and depressive disorder	0.642	0.358	0.000
S02.4 Fracture of malar and maxillary bones	0.641	0.359	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.639	0.361	0.000
N99-N99 Other disorders of the genitourinary system	0.638	0.362	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.638	0.362	0.000
B18 Chronic viral hepatitis	0.638	0.362	0.000
S82 Fracture of lower leg, including ankle	0.638	0.362	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.636	0.364	0.000
N15 Other renal tubulo-interstitial diseases	0.636	0.364	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.636	0.364	0.000
E83.4 Disorders of magnesium metabolism	0.636	0.364	0.000
S79 Other and unspecified injuries of hip and thigh	0.636	0.364	0.000
G90-G99 Other disorders of the nervous system	0.635	0.365	0.000
E27 Other disorders of adrenal gland	0.635	0.365	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.634	0.366	0.000
C17 Malignant neoplasm of small intestine	0.634	0.366	0.000
C23 Malignant neoplasm of gallbladder	0.634	0.366	0.000
M43 Other deforming dorsopathies	0.634	0.366	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.632	0.368	0.000
R01.2 Other cardiac sounds	0.631	0.369	0.000
R01.0 Benign and innocent cardiac murmurs	0.631	0.369	0.000
M94 Other disorders of cartilage	0.630	0.370	0.000
E67 Other hyperalimentation	0.630	0.370	0.000
E68 Sequelae of hyperalimentation	0.630	0.370	0.000
E65 Localised adiposity	0.630	0.370	0.000
M10 Gout	0.629	0.371	0.000
R26.3 Immobility	0.629	0.371	0.000
R26.1 Paralytic gait	0.629	0.371	0.000
M85.8 Other specified disorders of bone density and structure	0.628	0.371	0.000
S06.9 Intracranial injury, unspecified	0.628	0.372	0.000
S06.8 Other intracranial injuries	0.628	0.372	0.000
S06.7 Intracranial injury with prolonged coma	0.628	0.372	0.000
S06.4 Epidural haemorrhage	0.628	0.372	0.000
S06.3 Focal brain injury	0.628	0.372	0.000
S06.1 Traumatic cerebral oedema	0.628	0.372	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.628	0.372	0.000
S64.8 Injury of other nerves at wrist and hand level	0.628	0.372	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.628	0.372	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.628	0.372	0.000
S64.1 Injury of median nerve at wrist and hand level	0.628	0.372	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.627	0.373	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.627	0.373	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.627	0.373	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.627	0.373	0.000
E66.8 Other obesity	0.627	0.373	0.000
G70-G73 Diseases of myoneural junction and muscle	0.626	0.374	0.000
C18.3 Hepatic flexure	0.626	0.374	0.000
S78 Traumatic amputation of hip and thigh	0.625	0.375	0.000
S77 Crushing injury of hip and thigh	0.625	0.375	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.625	0.375	0.000
S75 Injury of blood vessels at hip and thigh level	0.625	0.375	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations