TreeWAS – Variant ID: rs79791727

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I25.2 Old myocardial infarction	0.999	0.001
Chapter VII Diseases of the eye and adnexa	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.995	0.005
I60-I69 Cerebrovascular diseases	0.988	0.012
Chapter XX External causes of morbidity and mortality	0.986	0.014
Chapter XV Pregnancy, childbirth and the puerperium	0.982	0.018
Chapter VIII Diseases of the ear and mastoid process	0.975	0.025
Chapter VI Diseases of the nervous system	0.968	0.032
I77 Other disorders of arteries and arterioles	0.966	0.034
H65-H75 Diseases of middle ear and mastoid	0.965	0.035
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.965	0.035
I67 Other cerebrovascular diseases	0.962	0.038
S00-S09 Injuries to the head	0.957	0.043
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.949	0.051
I20 Angina pectoris	0.947	0.053
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.946	0.054
Chapter IV Endocrine, nutritional and metabolic diseases	0.939	0.061
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.937	0.063
I21 Acute myocardial infarction	0.936	0.064
I25.8 Other forms of chronic ischaemic heart disease	0.935	0.065
I25.9 Chronic ischaemic heart disease, unspecified	0.932	0.068
Chapter XXII Codes for special purposes	0.927	0.073
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.924	0.076
I69 Sequelae of cerebrovascular disease	0.923	0.077
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.918	0.082
G20-G26 Extrapyramidal and movement disorders	0.915	0.085
H65 Nonsuppurative otitis media	0.915	0.085
I67.2 Cerebral atherosclerosis	0.911	0.089
I20.0 Unstable angina	0.908	0.092
O60-O75 Complications of labour and delivery	0.907	0.093
I21.2 Acute transmural myocardial infarction of other sites	0.907	0.093
H04 Disorders of lachrymal system	0.903	0.097
O94-O99 Other obstetric conditions, not elsewhere classified	0.903	0.097
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.899	0.101
H55-H59 Other disorders of eye and adnexa	0.891	0.109
S02 Fracture of skull and facial bones	0.890	0.110
I77.6 Arteritis, unspecified	0.888	0.112
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.883	0.117
I74 Arterial embolism and thrombosis	0.877	0.123
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.876	0.124
S60-S69 Injuries to the wrist and hand	0.876	0.124
H20 Iridocyclitis	0.874	0.126
I21.4 Acute subendocardial myocardial infarction	0.873	0.127
I70 Atherosclerosis	0.872	0.128
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.871	0.129
S10-S19 Injuries to the neck	0.859	0.141
I69.3 Sequelae of cerebral infarction	0.858	0.142
H65.3 Chronic mucoid otitis media	0.852	0.148
S90-S99 Injuries to the ankle and foot	0.851	0.149
S06 Intracranial injury	0.849	0.151
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.846	0.154
H40-H42 Glaucoma	0.845	0.155
H30-H36 Disorders of choroid and retina	0.844	0.156
G90-G99 Other disorders of the nervous system	0.843	0.157
S00 Superficial injury of head	0.842	0.158
I77.9 Disorder of arteries and arterioles, unspecified	0.842	0.158
I72 Other aneurysm	0.836	0.164
S40-S49 Injuries to the shoulder and upper arm	0.835	0.165
Y46 Antiepileptics and anti-Parkinsonism drugs	0.832	0.168
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.830	0.170
G80-G83 Cerebral palsy and other paralytic syndromes	0.830	0.170
T82.1 Mechanical complication of cardiac electronic device	0.829	0.171
H04.2 Epiphora	0.828	0.172
Q20-Q28 Congenital malformations of the circulatory system	0.825	0.175
H00 Hordeolum and chalazion	0.820	0.180
H66 Suppurative and unspecified otitis media	0.818	0.182
T92 Sequelae of injuries of upper limb	0.816	0.184
H74 Other disorders of middle ear and mastoid	0.815	0.185
O63 Long labour	0.815	0.185
E20-E35 Disorders of other endocrine glands	0.815	0.185
Q80-Q89 Other congenital malformations	0.814	0.186
O20-O29 Other maternal disorders predominantly related to pregnancy	0.813	0.187
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.809	0.191
G20 Parkinson's disease	0.808	0.192
E10-E14 Diabetes mellitus	0.808	0.192
S80-S89 Injuries to the knee and lower leg	0.806	0.194
H04.1 Other disorders of lachrymal gland	0.804	0.196
X58-X59 Accidental exposure to other and unspecified factors	0.803	0.197
I20.1 Angina pectoris with documented spasm	0.801	0.199
Y51 Drugs primarily affecting the autonomic nervous system	0.800	0.200
O85-O92 Complications predominantly related to the puerperium	0.798	0.202
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.796	0.204
T80 Complications following infusion, transfusion and therapeutic injection	0.788	0.212
I22 Subsequent myocardial infarction	0.788	0.212
I95-I99 Other and unspecified disorders of the circulatory system	0.787	0.213
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.785	0.215
I67.1 Cerebral aneurysm, nonruptured	0.785	0.215
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.784	0.216
I70.2 Atherosclerosis of arteries of the extremities	0.783	0.217
H46-H48 Disorders of optic nerve and visual pathways	0.783	0.217
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.782	0.218
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.778	0.222
Y43 Primarily systemic agents	0.778	0.222
I61 Intracerebral haemorrhage	0.776	0.223
S69 Other and unspecified injuries of wrist and hand	0.775	0.225
V10-V19 Pedal cyclist injured in transport accident	0.774	0.226
Y57 Other and unspecified drugs and medicaments	0.774	0.226
G25 Other extrapyramidal and movement disorders	0.774	0.226
H18 Other disorders of cornea	0.773	0.227
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.772	0.228
H70 Mastoiditis and related conditions	0.771	0.229
I67.8 Other specified cerebrovascular diseases	0.771	0.229
H20.9 Iridocyclitis, unspecified	0.769	0.231
I77.1 Stricture of artery	0.767	0.233
O75 Other complications of labour and delivery, not elsewhere classified	0.765	0.235
I78 Diseases of capillaries	0.764	0.236
H69 Other disorders of Eustachian tube	0.764	0.236
T90 Sequelae of injuries of head	0.763	0.237
S02.0 Fracture of vault of skull	0.763	0.237
O70 Perineal laceration during delivery	0.761	0.239
T20-T25 Burns and corrosions of external body surface, specified by site	0.761	0.239
W50-W64 Exposure to animate mechanical forces	0.757	0.243
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.755	0.245
H05 Disorders of orbit	0.755	0.245
S05 Injury of eye and orbit	0.754	0.246
U80 Agent resistant to penicillin and related antibiotics	0.752	0.248
I67.0 Dissection of cerebral arteries, nonruptured	0.750	0.250
H65.2 Chronic serous otitis media	0.749	0.251
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.749	0.251
G24 Dystonia	0.749	0.251
S66 Injury of muscle and tendon at wrist and hand level	0.748	0.252
E10 Insulin-dependent diabetes mellitus	0.748	0.252
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.748	0.252
H52 Disorders of refraction and accommodation	0.747	0.253
I77.8 Other specified disorders of arteries and arterioles	0.745	0.255
E00-E07 Disorders of thyroid gland	0.745	0.255
H55 Nystagmus and other irregular eye movements	0.743	0.257
I60 Subarachnoid haemorrhage	0.738	0.262
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.737	0.263
H40 Glaucoma	0.737	0.263
H00.1 Chalazion	0.737	0.263
S00.1 Contusion of eyelid and periocular area	0.736	0.264
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.735	0.264
I05-I09 Chronic rheumatic heart diseases	0.735	0.265
Chapter I Certain infectious and parasitic diseases	0.735	0.265
S42 Fracture of shoulder and upper arm	0.735	0.265
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.734	0.265
Y52 Agents primarily affecting the cardiovascular system	0.734	0.265
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.734	0.266
Q38-Q45 Other congenital malformations of the digestive system	0.731	0.269
H73 Other disorders of tympanic membrane	0.730	0.270
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.730	0.270
I73 Other peripheral vascular diseases	0.730	0.270
T79-T79 Certain early complications of trauma	0.729	0.271
O63.1 Prolonged second stage (of labour)	0.728	0.272
H72 Perforation of tympanic membrane	0.726	0.274
H20.8 Other iridocyclitis	0.723	0.277
G40-G47 Episodic and paroxysmal disorders	0.722	0.278
Q60-Q64 Congenital malformations of the urinary system	0.721	0.279
X20-X29 Contact with venomous animals and plants	0.721	0.279
G00-G09 Inflammatory diseases of the central nervous system	0.721	0.279
W20-W49 Exposure to inanimate mechanical forces	0.720	0.280
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.720	0.280
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.718	0.282
I69.1 Sequelae of intracerebral haemorrhage	0.718	0.282
I74.5 Embolism and thrombosis of iliac artery	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
E16 Other disorders of pancreatic internal secretion	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
T88 Other complications of surgical and medical care, not elsewhere classified	0.715	0.285
H52.1 Myopia	0.715	0.285
G30-G32 Other degenerative diseases of the nervous system	0.715	0.285
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.714	0.286
O72 Postpartum haemorrhage	0.712	0.288
X40-X49 Accidental poisoning by and exposure to noxious substances	0.712	0.288
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.711	0.289
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.711	0.289
H50 Other strabismus	0.711	0.289
E10.9 Without complications	0.711	0.289
T66-T78 Other and unspecified effects of external causes	0.710	0.290
G81 Hemiplegia	0.710	0.290
S02.1 Fracture of base of skull	0.709	0.291
I68 Cerebrovascular disorders in diseases classified elsewhere	0.709	0.291
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.709	0.291
S30 Superficial injury of abdomen, lower back and pelvis	0.708	0.291
S19 Other and unspecified injuries of neck	0.708	0.292
Y35-Y36 Legal intervention and operations of war	0.707	0.293
Y10-Y34 Event of undetermined intent	0.707	0.293
Y00-Y09 Assault	0.707	0.293
X85-X99 Assault	0.707	0.293
X50-X57 Overexertion, travel and privation	0.707	0.293
X30-X39 Exposure to forces of nature	0.707	0.293
X10-X19 Contact with heat and hot substances	0.707	0.293
X00-X09 Exposure to smoke, fire and flames	0.707	0.293
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293
W75-W84 Other accidental threats to breathing	0.707	0.293
W65-W74 Accidental drowning and submersion	0.707	0.293
V98-V99 Other and unspecified transport accidents	0.707	0.293
V95-V97 Air and space transport accidents	0.707	0.293
V90-V94 Water transport accidents	0.707	0.293
V80-V89 Other land transport accidents	0.707	0.293
V70-V79 Bus occupant injured in transport accident	0.707	0.293
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293
V40-V49 Car occupant injured in transport accident	0.707	0.293
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293
V01-V09 Pedestrian injured in transport accident	0.707	0.293
S02.4 Fracture of malar and maxillary bones	0.706	0.294
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.706	0.294
T82.0 Mechanical complication of heart valve prosthesis	0.704	0.296
H20.0 Acute and subacute iridocyclitis	0.702	0.298
S69.9 Unspecified injury of wrist and hand	0.702	0.298
T87 Complications peculiar to reattachment and amputation	0.702	0.298
G35-G37 Demyelinating diseases of the central nervous system	0.702	0.298
S00.8 Superficial injury of other parts of head	0.702	0.298
S02.6 Fracture of mandible	0.701	0.299
H57 Other disorders of eye and adnexa	0.700	0.300
G47 Sleep disorders	0.700	0.300
I63 Cerebral infarction	0.700	0.300
S02.8 Fractures of other skull and facial bones	0.699	0.301
Y46.2 Hydantoin derivatives	0.699	0.301
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.698	0.302
S37 Injury of urinary and pelvic organs	0.698	0.302
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.698	0.302
S12 Fracture of neck	0.696	0.304
O70.0 First degree perineal laceration during delivery	0.696	0.304
T80.2 Infections following infusion, transfusion and therapeutic injection	0.695	0.305
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.694	0.306
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.694	0.306
T15-T19 Effects of foreign body entering through natural orifice	0.694	0.306
Q85 Phakomatoses, not elsewhere classified	0.694	0.306
I77.5 Necrosis of artery	0.693	0.307
I77.4 Coeliac artery compression syndrome	0.693	0.307
I77.3 Arterial fibromuscular dysplasia	0.693	0.307
I77.2 Rupture of artery	0.693	0.307
I77.0 Arteriovenous fistula, acquired	0.693	0.307
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.692	0.308
H68 Eustachian salpingitis and obstruction	0.692	0.308
H67 Otitis media in diseases classified elsewhere	0.692	0.308
Y59 Other and unspecified vaccines and biological substances	0.692	0.308
Y58 Bacterial vaccines	0.692	0.308
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.692	0.308
Y53 Agents primarily affecting the gastro-intestinal system	0.692	0.308
Y50 Central nervous system stimulants, not elsewhere classified	0.692	0.308
Y49 Psychotropic drugs, not elsewhere classified	0.692	0.308
Y48 Anaesthetics and therapeutic gases	0.692	0.308
Y47 Sedatives, hypnotics and antianxiety drugs	0.692	0.308
S20-S29 Injuries to the thorax	0.691	0.309
O62 Abnormalities of forces of labour	0.690	0.310
I67.7 Cerebral arteritis, not elsewhere classified	0.689	0.310
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.689	0.310
I67.5 Moyamoya disease	0.689	0.310
I67.4 Hypertensive encephalopathy	0.689	0.310
I67.3 Progressive vascular leukoencephalopathy	0.689	0.310
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.688	0.312
O20 Haemorrhage in early pregnancy	0.688	0.312
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.687	0.312
E70-E90 Metabolic disorders	0.688	0.312
S32 Fracture of lumbar spine and pelvis	0.687	0.313
Y40 Systemic antibiotics	0.687	0.313
E29 Testicular dysfunction	0.686	0.314
S08 Traumatic amputation of part of head	0.686	0.314
S07 Crushing injury of head	0.686	0.314
S04 Injury of cranial nerves	0.686	0.314
S03 Dislocation, sprain and strain of joints and ligaments of head	0.686	0.314
H65.9 Nonsuppurative otitis media, unspecified	0.686	0.314
I30-I52 Other forms of heart disease	0.686	0.314
H10-H13 Disorders of conjunctiva	0.685	0.315
W00-W19 Falls	0.685	0.315
Q21 Congenital malformations of cardiac septa	0.684	0.316
I64 Stroke, not specified as haemorrhage or infarction	0.683	0.317
H66.9 Otitis media, unspecified	0.681	0.319
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.681	0.319
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.681	0.319
Q35-Q37 Cleft lip and cleft palate	0.681	0.319
Q30-Q34 Congenital malformations of the respiratory system	0.681	0.319
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.681	0.319
Q00-Q07 Congenital malformations of the nervous system	0.681	0.319
S92 Fracture of foot, except ankle	0.680	0.320
H03 Disorders of eyelid in diseases classified elsewhere	0.679	0.321
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.678	0.322
Y41 Other systemic anti-infectives and antiparasitics	0.678	0.322
G96 Other disorders of central nervous system	0.677	0.323
S60 Superficial injury of wrist and hand	0.677	0.323
I69.0 Sequelae of subarachnoid haemorrhage	0.675	0.325
E50-E64 Other nutritional deficiencies	0.675	0.325
O69 Labour and delivery complicated by umbilical cord complications	0.674	0.325
I67.9 Cerebrovascular disease, unspecified	0.673	0.327
Y86 Sequelae of other accidents	0.673	0.327
X58 Exposure to other specified factors	0.672	0.327
S06.0 Concussion	0.672	0.328
S02.00 Fracture of vault of skull (closed)	0.672	0.328
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.672	0.328
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.672	0.328
H17 Corneal scars and opacities	0.672	0.328
H15 Disorders of sclera	0.672	0.328
I21.X Presumed acute myicardial infaction (unconfirmed)	0.671	0.329
I21.3 Acute transmural myocardial infarction of unspecified site	0.671	0.329
I62 Other nontraumatic intracranial haemorrhage	0.669	0.331
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.669	0.331
H33 Retinal detachments and breaks	0.669	0.331
I44 Atrioventricular and left bundle-branch block	0.669	0.331
T93 Sequelae of injuries of lower limb	0.669	0.331
V20-V29 Motorcycle rider injured in transport accident	0.668	0.332
H34 Retinal vascular occlusions	0.668	0.332
H35 Other retinal disorders	0.668	0.332
U88 Agent resistant to multiple antibiotics	0.667	0.333
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.667	0.333
O63.0 Prolonged first stage (of labour)	0.666	0.334
Y44 Agents primarily affecting blood constituents	0.666	0.334
O90 Complications of the puerperium, not elsewhere classified	0.665	0.335
Y46.4 Iminostilbenes	0.665	0.335
H90-H95 Other disorders of ear	0.664	0.336
S90 Superficial injury of ankle and foot	0.664	0.336
U80.1 Methicillin resistant agent	0.663	0.337
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.663	0.337
G90 Disorders of autonomic nervous system	0.663	0.337
H60-H62 Diseases of external ear	0.663	0.337
Q50-Q56 Congenital malformations of genital organs	0.662	0.337
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.662	0.338
H74.8 Other specified disorders of middle ear and mastoid	0.661	0.339
H21 Other disorders of iris and ciliary body	0.661	0.339
I25.1 Atherosclerotic heart disease	0.661	0.339
O16 Unspecified maternal hypertension	0.661	0.339
I72.4 Aneurysm of artery of lower extremity	0.660	0.340
G47.3 Sleep apnoea	0.660	0.340
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.660	0.340
S91 Open wound of ankle and foot	0.660	0.340
E28 Ovarian dysfunction	0.660	0.340
S06.4 Epidural haemorrhage	0.659	0.341
S83.2 Tear of meniscus, current	0.659	0.341
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.658	0.341
Q23 Congenital malformations of aortic and mitral valves	0.658	0.342
T98 Sequelae of other and unspecified effects of external causes	0.658	0.342
T95 Sequelae of burns, corrosions and frostbite	0.658	0.342
T94 Sequelae of injuries involving multiple and unspecified body regions	0.658	0.342
T91 Sequelae of injuries of neck and trunk	0.658	0.342
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.658	0.342
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.658	0.342
G70-G73 Diseases of myoneural junction and muscle	0.657	0.343
G23 Other degenerative diseases of basal ganglia	0.656	0.344
G21 Secondary Parkinsonism	0.656	0.344
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.656	0.344
G22 Parkinsonism in diseases classified elsewhere	0.656	0.344
I25.5 Ischaemic cardiomyopathy	0.656	0.344
H65.4 Other chronic nonsuppurative otitis media	0.656	0.344
H65.1 Other acute nonsuppurative otitis media	0.656	0.344
H65.0 Acute serous otitis media	0.656	0.344
S06.6 Traumatic subarachnoid haemorrhage	0.656	0.344
H40.5 Glaucoma secondary to other eye disorders	0.655	0.345
Y60-Y69 Misadventures to patients during surgical and medical care	0.655	0.345
I25.3 Aneurysm of heart	0.654	0.345
S02.3 Fracture of orbital floor	0.654	0.346
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.653	0.346
H74.0 Tympanosclerosis	0.653	0.347
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.653	0.347
H16 Keratitis	0.652	0.348
T86 Failure and rejection of transplanted organs and tissues	0.652	0.348
H43-H45 Disorders of vitreous body and globe	0.651	0.349
G95 Other diseases of spinal cord	0.651	0.349
X60-X84 Intentional self-harm	0.650	0.349
O74 Complications of anaesthesia during labour and delivery	0.650	0.349
O71 Other obstetric trauma	0.650	0.349
O65 Obstructed labour due to maternal pelvic abnormality	0.650	0.349
O61 Failed induction of labour	0.650	0.349
O60 Preterm delivery	0.650	0.349
I20.9 Angina pectoris, unspecified	0.650	0.350
E16.2 Hypoglycaemia, unspecified	0.650	0.350
S64 Injury of nerves at wrist and hand level	0.649	0.350
I72.0 Aneurysm of carotid artery	0.648	0.352
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.648	0.352
H04.9 Disorder of lachrymal system, unspecified	0.648	0.352
H04.8 Other disorders of lachrymal system	0.648	0.352
H04.6 Other changes in lachrymal passages	0.648	0.352
H04.4 Chronic inflammation of lachrymal passages	0.648	0.352
H04.3 Acute and unspecified inflammation of lachrymal passages	0.648	0.352
H04.0 Dacryoadenitis	0.648	0.352
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.647	0.352
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.647	0.353
O97 Death from sequelae of direct obstetric causes	0.647	0.353
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.647	0.353
O95 Obstetric death of unspecified cause	0.647	0.353
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.647	0.353
H18.8 Other specified disorders of cornea	0.647	0.353
T92.1 Sequelae of fracture of arm	0.646	0.354
S67 Crushing injury of wrist and hand	0.646	0.354
Y45.0 Opioids and related analgesics	0.645	0.355
I44.1 Atrioventricular block, second degree	0.645	0.355
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.644	0.356
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.644	0.356
T82.4 Mechanical complication of vascular dialysis catheter	0.644	0.356
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.644	0.356
Y43.3 Other antineoplastic drugs	0.644	0.356
I22.0 Subsequent myocardial infarction of anterior wall	0.644	0.356
S00.0 Superficial injury of scalp	0.643	0.357
S06.2 Diffuse brain injury	0.643	0.357
Y57.5 X-ray contrast media	0.643	0.357
H47 Other disorders of optic [2nd] nerve and visual pathways	0.643	0.357
I72.8 Aneurysm of other specified arteries	0.642	0.358
O75.8 Other specified complications of labour and delivery	0.642	0.358
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.641	0.359
S06.8 Other intracranial injuries	0.640	0.360
I78.0 Hereditary haemorrhagic telangiectasia	0.639	0.360
S42.1 Fracture of scapula	0.640	0.360
H66.3 Other chronic suppurative otitis media	0.639	0.361
S02.9 Fracture of skull and facial bones, part unspecified	0.638	0.362
S02.7 Multiple fractures involving skull and facial bones	0.638	0.362
S02.5 Fracture of tooth	0.638	0.362
S06.5 Traumatic subdural haemorrhage	0.637	0.363
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.637	0.363
H71 Cholesteatoma of middle ear	0.634	0.366
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.634	0.366
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.633	0.367
S36 Injury of intra-abdominal organs	0.633	0.367
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.633	0.367
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.633	0.367
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.633	0.367
S31 Open wound of abdomen, lower back and pelvis	0.633	0.367
T82.3 Mechanical complication of other vascular grafts	0.633	0.367
H04.5 Stenosis and insufficiency of lachrymal passages	0.633	0.367
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.632	0.368
H70.9 Mastoiditis, unspecified	0.632	0.368
S50-S59 Injuries to the elbow and forearm	0.631	0.369
Q24 Other congenital malformations of heart	0.630	0.370
E24 Cushing's syndrome	0.630	0.370
T92.2 Sequelae of fracture at wrist and hand level	0.630	0.370
G24.9 Dystonia, unspecified	0.629	0.370
I74.9 Embolism and thrombosis of unspecified artery	0.629	0.371
I74.8 Embolism and thrombosis of other arteries	0.629	0.371
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.629	0.371
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.629	0.371
I74.0 Embolism and thrombosis of abdominal aorta	0.629	0.371
G25.3 Myoclonus	0.629	0.371
E23 Hypofunction and other disorders of pituitary gland	0.628	0.371
H51 Other disorders of binocular movement	0.628	0.371
H49 Paralytic strabismus	0.628	0.371
S65 Injury of blood vessels at wrist and hand level	0.628	0.371
H20.2 Lens-induced iridocyclitis	0.627	0.373
H20.1 Chronic iridocyclitis	0.627	0.373
I70.9 Generalised and unspecified atherosclerosis	0.625	0.375
I70.8 Atherosclerosis of other arteries	0.625	0.375
I70.1 Atherosclerosis of renal artery	0.625	0.375
I70.0 Atherosclerosis of aorta	0.625	0.375
I61.9 Intracerebral haemorrhage, unspecified	0.625	0.375
T92.0 Sequelae of open wound of upper limb	0.624	0.375
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.624	0.376
O15 Eclampsia	0.624	0.376
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.624	0.376
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.624	0.376
G81.9 Hemiplegia, unspecified	0.624	0.376
Y77 Ophthalmic devices associated with adverse incidents	0.624	0.376
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.624	0.376
V18 Pedal cyclist injured in noncollision transport accident	0.623	0.377
I24 Other acute ischaemic heart diseases	0.622	0.377
S46 Injury of muscle and tendon at shoulder and upper arm level	0.622	0.377
U51 Admission status on psychiatric patients	0.622	0.378
E87 Other disorders of fluid, electrolyte and acid-base balance	0.620	0.380
S41 Open wound of shoulder and upper arm	0.620	0.380
H18.4 Corneal degeneration	0.619	0.380
H02 Other disorders of eyelid	0.619	0.380
H72.9 Perforation of tympanic membrane, unspecified	0.619	0.381
S66.8 Injury of other muscles and tendons at wrist and hand level	0.619	0.381
E40-E46 Malnutrition	0.619	0.381
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.619	0.381
G47.9 Sleep disorder, unspecified	0.618	0.382
T90.5 Sequelae of intracranial injury	0.618	0.382
O75.0 Maternal distress during labour and delivery	0.618	0.382
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.617	0.383
E27 Other disorders of adrenal gland	0.616	0.384
O26 Maternal care for other conditions predominantly related to pregnancy	0.616	0.384
S17 Crushing injury of neck	0.616	0.384
S15 Injury of blood vessels at neck level	0.616	0.384
S14 Injury of nerves and spinal cord at neck level	0.616	0.384
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.616	0.384
S11 Open wound of neck	0.616	0.384
S10 Superficial injury of neck	0.616	0.384
S18 Traumatic amputation at neck level	0.616	0.384
S16 Injury of muscle and tendon at neck level	0.616	0.384
S49 Other and unspecified injuries of shoulder and upper arm	0.615	0.385
G91 Hydrocephalus	0.614	0.386
I05 Rheumatic mitral valve diseases	0.613	0.386
G83 Other paralytic syndromes	0.612	0.388
I71 Aortic aneurysm and dissection	0.611	0.389
S00.7 Multiple superficial injuries of head	0.611	0.389
G99 Other disorders of nervous system in diseases classified elsewhere	0.611	0.389
E26 Hyperaldosteronism	0.611	0.389
S70-S79 Injuries to the hip and thigh	0.611	0.389
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.611	0.389
S99 Other and unspecified injuries of ankle and foot	0.610	0.390
S98 Traumatic amputation of ankle and foot	0.610	0.390
S97 Crushing injury of ankle and foot	0.610	0.390
S96 Injury of muscle and tendon at ankle and foot level	0.610	0.390
S95 Injury of blood vessels at ankle and foot level	0.610	0.390
S94 Injury of nerves at ankle and foot level	0.610	0.390
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.610	0.390
H50.5 Heterophoria	0.610	0.390
G80 Infantile cerebral palsy	0.610	0.390
S06.9 Intracranial injury, unspecified	0.609	0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations