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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80123541
log Bayes Factor = 17.2266
Chromosome 6   position 110,354,662  (GRCh37) Explore rs80123541 on Ensembl!
Variant rs80123541 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
J09-J18 Influenza and pneumonia
0.997 0.003 0.000
J18 Pneumonia, organism unspecified
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Z90.7 Acquired absence of genital organ(s)
0.992 0.008 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
I25 Chronic ischaemic heart disease
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.981 0.019 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.978 0.022 0.000
I20 Angina pectoris
0.977 0.023 0.000
J40-J47 Chronic lower respiratory diseases
0.977 0.023 0.000
J18.9 Pneumonia, unspecified
0.968 0.032 0.000
I21 Acute myocardial infarction
0.967 0.033 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.964 0.036 0.000
I20.9 Angina pectoris, unspecified
0.962 0.038 0.000
C15-C26 Malignant neoplasms of digestive organs
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.958 0.042 0.000
J18.1 Lobar pneumonia, unspecified
0.956 0.044 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.956 0.044 0.000
J44 Other chronic obstructive pulmonary disease
0.956 0.044 0.000
Z83 Family history of other specific disorders
0.955 0.045 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.955 0.045 0.000
M45-M49 Spondylopathies
0.954 0.046 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.947 0.053 0.000
I50 Heart failure
0.945 0.055 0.000
B95-B98 Bacterial, viral and other infectious agents
0.945 0.055 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.939 0.061 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.939 0.061 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.938 0.062 0.000
M20-M25 Other joint disorders
0.937 0.063 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.934 0.066 0.000
J90-J94 Other diseases of pleura
0.930 0.070 0.000
M47 Spondylosis
0.926 0.074 0.000
I05-I09 Chronic rheumatic heart diseases
0.923 0.077 0.000
I44 Atrioventricular and left bundle-branch block
0.922 0.078 0.000
C15 Malignant neoplasm of oesophagus
0.920 0.080 0.000
I50.1 Left ventricular failure
0.916 0.084 0.000
Chapter XX External causes of morbidity and mortality
0.912 0.088 0.000
I42 Cardiomyopathy
0.912 0.088 0.000
F30-F39 Mood [affective] disorders
0.907 0.093 0.000
E00-E07 Disorders of thyroid gland
0.903 0.097 0.000
M20 Acquired deformities of fingers and toes
0.902 0.098 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.900 0.100 0.000
Z92 Personal history of medical treatment
0.900 0.100 0.000
C79 Secondary malignant neoplasm of other sites
0.899 0.101 0.000
H65-H75 Diseases of middle ear and mastoid
0.899 0.101 0.000
I71 Aortic aneurysm and dissection
0.898 0.102 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.894 0.106 0.000
Z99.1 Dependence on respirator
0.894 0.106 0.000
J43 Emphysema
0.894 0.106 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.893 0.107 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.892 0.108 0.000
M50-M54 Other dorsopathies
0.890 0.110 0.000
M20.1 Hallux valgus (acquired)
0.889 0.111 0.000
J95-J99 Other diseases of the respiratory system
0.887 0.112 0.000
Chapter XIV Diseases of the genitourinary system
0.887 0.113 0.000
C80 Malignant neoplasm without specification of site
0.884 0.116 0.000
D00-D09 In situ neoplasms
0.882 0.118 0.000
J18.0 Bronchopneumonia, unspecified
0.880 0.120 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.878 0.122 0.000
Z98 Other postsurgical states
0.876 0.124 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.868 0.132 0.000
Z83.5 Family history of eye and ear disorders
0.864 0.136 0.000
B35-B49 Mycoses
0.863 0.137 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.862 0.138 0.000
Z88.2 Personal history of allergy to sulphonamides
0.860 0.140 0.000
Z90.1 Acquired absence of breast(s)
0.858 0.142 0.000
N40-N51 Diseases of male genital organs
0.856 0.144 0.000
C15.9 Oesophagus, unspecified
0.856 0.144 0.000
M47.9 Spondylosis, unspecified
0.854 0.145 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.851 0.149 0.000
A30-A49 Other bacterial diseases
0.849 0.151 0.000
M54 Dorsalgia
0.846 0.154 0.000
I42.0 Dilated cardiomyopathy
0.846 0.154 0.000
N20-N23 Urolithiasis
0.845 0.155 0.000
M47.8 Other spondylosis
0.845 0.155 0.000
J92 Pleural plaque
0.843 0.157 0.000
Z80 Family history of malignant neoplasm
0.841 0.159 0.000
I72 Other aneurysm
0.840 0.160 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.839 0.161 0.000
I24 Other acute ischaemic heart diseases
0.837 0.163 0.000
J43.9 Emphysema, unspecified
0.835 0.165 0.000
I25.1 Atherosclerotic heart disease
0.831 0.169 0.000
E05.9 Thyrotoxicosis, unspecified
0.829 0.171 0.000
F80-F89 Disorders of psychological development
0.828 0.172 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.826 0.174 0.000
N41 Inflammatory diseases of prostate
0.825 0.175 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.825 0.175 0.000
I21.4 Acute subendocardial myocardial infarction
0.823 0.177 0.000
C78.0 Secondary malignant neoplasm of lung
0.823 0.177 0.000
I70 Atherosclerosis
0.822 0.178 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.821 0.179 0.000
I73 Other peripheral vascular diseases
0.821 0.179 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.817 0.183 0.000
I05 Rheumatic mitral valve diseases
0.816 0.184 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.815 0.185 0.000
M25 Other joint disorders, not elsewhere classified
0.814 0.186 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.812 0.188 0.000
I44.7 Left bundle-branch block, unspecified
0.811 0.189 0.000
I44.0 Atrioventricular block, first degree
0.811 0.189 0.000
C15.5 Lower third of oesophagus
0.810 0.190 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.810 0.190 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.808 0.192 0.000
I31 Other diseases of pericardium
0.805 0.195 0.000
Z83.3 Family history of diabetes mellitus
0.805 0.195 0.000
I08 Multiple valve diseases
0.804 0.196 0.000
F32 Depressive episode
0.803 0.197 0.000
I25.2 Old myocardial infarction
0.801 0.199 0.000
C78.2 Secondary malignant neoplasm of pleura
0.801 0.199 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.798 0.202 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.796 0.204 0.000
E20-E35 Disorders of other endocrine glands
0.795 0.205 0.000
T81 Complications of procedures, not elsewhere classified
0.791 0.209 0.000
J98 Other respiratory disorders
0.790 0.210 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.790 0.210 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.786 0.214 0.000
M40-M43 Deforming dorsopathies
0.786 0.214 0.000
N20 Calculus of kidney and ureter
0.784 0.216 0.000
M54.9 Dorsalgia, unspecified
0.782 0.218 0.000
Z83.7 Family history of diseases of the digestive system
0.781 0.219 0.000
M47.86 Other spondylosis (Lumbar region)
0.781 0.219 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.781 0.219 0.000
Z88.0 Personal history of allergy to penicillin
0.779 0.221 0.000
B37 Candidiasis
0.775 0.225 0.000
C80.9 Malignant neoplasm, unspecified
0.774 0.226 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.774 0.226 0.000
B25-B34 Other viral diseases
0.773 0.227 0.000
E07 Other disorders of thyroid
0.771 0.229 0.000
E10-E14 Diabetes mellitus
0.769 0.231 0.000
J81 Pulmonary oedema
0.769 0.231 0.000
I77 Other disorders of arteries and arterioles
0.768 0.232 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.764 0.236 0.000
D05 Carcinoma in situ of breast
0.763 0.237 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.763 0.237 0.000
J42 Unspecified chronic bronchitis
0.763 0.237 0.000
Z96 Presence of other functional implants
0.763 0.237 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.763 0.237 0.000
C16 Malignant neoplasm of stomach
0.763 0.237 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.762 0.238 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
N42 Other disorders of prostate
0.760 0.240 0.000
H73 Other disorders of tympanic membrane
0.759 0.241 0.000
M25.5 Pain in joint
0.758 0.242 0.000
F31 Bipolar affective disorder
0.757 0.243 0.000
M65-M68 Disorders of synovium and tendon
0.757 0.243 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.756 0.244 0.000
C25 Malignant neoplasm of pancreas
0.756 0.244 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.756 0.244 0.000
C78.7 Secondary malignant neoplasm of liver
0.755 0.245 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.755 0.245 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.754 0.246 0.000
H80-H83 Diseases of inner ear
0.753 0.247 0.000
H71 Cholesteatoma of middle ear
0.752 0.248 0.000
M80-M85 Disorders of bone density and structure
0.752 0.248 0.000
H65 Nonsuppurative otitis media
0.752 0.248 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.750 0.250 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.749 0.251 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.749 0.251 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.749 0.251 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.749 0.251 0.000
I30 Acute pericarditis
0.748 0.252 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.747 0.253 0.000
E65-E68 Obesity and other hyperalimentation
0.746 0.254 0.000
C50-C50 Malignant neoplasm of breast
0.745 0.255 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.744 0.255 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.744 0.256 0.000
I73.0 Raynaud's syndrome
0.744 0.256 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.742 0.258 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.742 0.258 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.742 0.258 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.742 0.258 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.741 0.259 0.000
I35 Nonrheumatic aortic valve disorders
0.741 0.259 0.000
M34 Systemic sclerosis
0.740 0.260 0.000
J90 Pleural effusion, not elsewhere classified
0.739 0.261 0.000
S60-S69 Injuries to the wrist and hand
0.738 0.261 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.737 0.263 0.000
J92.0 Pleural plaque with presence of asbestos
0.735 0.265 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.734 0.266 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.734 0.266 0.000
Z98.0 Intestinal bypass and anastomosis status
0.733 0.267 0.000
F32.9 Depressive episode, unspecified
0.733 0.267 0.000
N10-N16 Renal tubulo-interstitial diseases
0.733 0.267 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.732 0.268 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.731 0.269 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.729 0.271 0.000
I49 Other cardiac arrhythmias
0.728 0.271 0.000
H90-H95 Other disorders of ear
0.727 0.273 0.000
M31 Other necrotising vasculopathies
0.725 0.275 0.000
J94 Other pleural conditions
0.725 0.275 0.000
Z97 Presence of other devices
0.724 0.276 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.724 0.276 0.000
N23 Unspecified renal colic
0.723 0.277 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.723 0.277 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.722 0.278 0.000
I22 Subsequent myocardial infarction
0.722 0.278 0.000
J00-J06 Acute upper respiratory infections
0.721 0.279 0.000
C79.6 Secondary malignant neoplasm of ovary
0.721 0.279 0.000
C64-C68 Malignant neoplasms of urinary tract
0.721 0.279 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.720 0.279 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.720 0.280 0.000
M86-M90 Other osteopathies
0.720 0.280 0.000
A41 Other septicaemia
0.720 0.280 0.000
N20.1 Calculus of ureter
0.719 0.281 0.000
C79.2 Secondary malignant neoplasm of skin
0.718 0.282 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.717 0.282 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
I50.0 Congestive heart failure
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
N41.1 Chronic prostatitis
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
Z90.8 Acquired absence of other organs
0.715 0.284 0.000
Z90.0 Acquired absence of part of head and neck
0.715 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
Z98.8 Other specified postsurgical states
0.715 0.285 0.000
J17 Pneumonia in diseases classified elsewhere
0.715 0.285 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.715 0.285 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.715 0.285 0.000
J12 Viral pneumonia, not elsewhere classified
0.715 0.285 0.000
J11 Influenza, virus not identified
0.715 0.285 0.000
J10 Influenza due to identified influenza virus
0.715 0.285 0.000
J14 Pneumonia due to Haemophilus influenzae
0.715 0.285 0.000
J09 Influenza due to certain identified influenza virus
0.715 0.285 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.715 0.285 0.000
I25.5 Ischaemic cardiomyopathy
0.715 0.285 0.000
D04 Carcinoma in situ of skin
0.715 0.285 0.000
M46 Other inflammatory spondylopathies
0.714 0.286 0.000
I08.0 Disorders of both mitral and aortic valves
0.714 0.286 0.000
J18.8 Other pneumonia, organism unspecified
0.713 0.286 0.000
J18.2 Hypostatic pneumonia, unspecified
0.713 0.286 0.000
W00-W19 Falls
0.713 0.287 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
Z99.8 Dependence on other enabling machines and devices
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
M25.56 Pain in joint (Lower leg)
0.712 0.288 0.000
J80 Adult respiratory distress syndrome
0.710 0.290 0.000
J46 Status asthmaticus
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.291 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.709 0.291 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
I25.6 Silent myocardial ischaemia
0.707 0.292 0.000
I25.4 Coronary artery aneurysm
0.707 0.292 0.000
I25.3 Aneurysm of heart
0.707 0.292 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.707 0.292 0.000
T66-T78 Other and unspecified effects of external causes
0.707 0.293 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.706 0.294 0.000
J60-J70 Lung diseases due to external agents
0.706 0.294 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.706 0.294 0.000
J92.9 Pleural plaque without asbestos
0.705 0.295 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.704 0.296 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.704 0.296 0.000
F99-F99 Unspecified mental disorder
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
F70-F79 Mental retardation
0.703 0.297 0.000
F60-F69 Disorders of adult personality and behaviour
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.701 0.299 0.000
H66 Suppurative and unspecified otitis media
0.701 0.299 0.000
I20.1 Angina pectoris with documented spasm
0.700 0.300 0.000
J41 Simple and mucopurulent chronic bronchitis
0.700 0.300 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.699 0.301 0.000
H69 Other disorders of Eustachian tube
0.699 0.301 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.698 0.302 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.698 0.302 0.000
I20.0 Unstable angina
0.697 0.303 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.696 0.304 0.000
I42.9 Cardiomyopathy, unspecified
0.696 0.304 0.000
E50-E64 Other nutritional deficiencies
0.696 0.304 0.000
I72.3 Aneurysm of iliac artery
0.695 0.305 0.000
Z99.3 Dependence on wheelchair
0.695 0.305 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.695 0.305 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.695 0.305 0.000
Z57 Occupational exposure to risk-factors
0.695 0.305 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.693 0.306 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.693 0.306 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.693 0.306 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.693 0.307 0.000
M54.3 Sciatica
0.693 0.307 0.000
S40-S49 Injuries to the shoulder and upper arm
0.693 0.307 0.000
N99-N99 Other disorders of the genitourinary system
0.692 0.308 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.691 0.309 0.000
W20-W49 Exposure to inanimate mechanical forces
0.691 0.309 0.000
Z92.0 Personal history of contraception
0.690 0.310 0.000
I44.2 Atrioventricular block, complete
0.689 0.310 0.000
M47.2 Other spondylosis with radiculopathy
0.689 0.311 0.000
N50 Other disorders of male genital organs
0.687 0.312 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.687 0.312 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.687 0.312 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.687 0.312 0.000
C21 Malignant neoplasm of anus and anal canal
0.687 0.312 0.000
C17 Malignant neoplasm of small intestine
0.687 0.312 0.000
C23 Malignant neoplasm of gallbladder
0.687 0.312 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.687 0.313 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.687 0.313 0.000
E40-E46 Malnutrition
0.687 0.313 0.000
M20.3 Other deformity of hallux (acquired)
0.685 0.314 0.000
Z83.6 Family history of diseases of the respiratory system
0.684 0.315 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.684 0.315 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.684 0.315 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.684 0.315 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.684 0.315 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.684 0.316 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.684 0.316 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.684 0.316 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.684 0.316 0.000
I31.3 Pericardial effusion (noninflammatory)
0.684 0.316 0.000
M49 Spondylopathies in diseases classified elsewhere
0.684 0.316 0.000
M45 Ankylosing spondylitis
0.684 0.316 0.000
T33-T35 Frostbite
0.684 0.316 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.684 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.316 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.684 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
M05-M14 Inflammatory polyarthropathies
0.683 0.317 0.000
D05.1 Intraductal carcinoma in situ
0.681 0.319 0.000
I27 Other pulmonary heart diseases
0.680 0.319 0.000
F33 Recurrent depressive disorder
0.680 0.320 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.679 0.321 0.000
I05.2 Mitral stenosis with insufficiency
0.679 0.321 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.678 0.321 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.678 0.322 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.678 0.322 0.000
Z93 Artificial opening status
0.677 0.322 0.000
I46 Cardiac arrest
0.677 0.323 0.000
I72.4 Aneurysm of artery of lower extremity
0.677 0.323 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
F80 Specific developmental disorders of speech and language
0.676 0.324 0.000
E07.9 Disorder of thyroid, unspecified
0.676 0.324 0.000
J84 Other interstitial pulmonary diseases
0.675 0.325 0.000
C43 Malignant melanoma of skin
0.674 0.326 0.000
J40 Bronchitis, not specified as acute or chronic
0.674 0.326 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.673 0.327 0.000
Z99.4 Dependence on artificial heart
0.673 0.327 0.000
Z99.0 Dependence on aspirator
0.673 0.327 0.000
I78 Diseases of capillaries
0.673 0.327 0.000
N60-N64 Disorders of breast
0.673 0.327 0.000
T87 Complications peculiar to reattachment and amputation
0.673 0.327 0.000
T86 Failure and rejection of transplanted organs and tissues
0.673 0.327 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.673 0.327 0.000
T93 Sequelae of injuries of lower limb
0.673 0.327 0.000
N41.0 Acute prostatitis
0.672 0.328 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.672 0.328 0.000
M33 Dermatopolymyositis
0.672 0.328 0.000
M32 Systemic lupus erythematosus
0.672 0.328 0.000
M30 Polyarteritis nodosa and related conditions
0.672 0.328 0.000
M21 Other acquired deformities of limbs
0.672 0.328 0.000
C51-C58 Malignant neoplasms of female genital organs
0.671 0.329 0.000
J98.1 Pulmonary collapse
0.670 0.330 0.000
Z90.3 Acquired absence of part of stomach
0.669 0.331 0.000
I21.9 Acute myocardial infarction, unspecified
0.669 0.331 0.000
I51 Complications and ill-defined descriptions of heart disease
0.668 0.332 0.000
C77.2 Intra-abdominal lymph nodes
0.668 0.332 0.000
B37.0 Candidal stomatitis
0.667 0.333 0.000
I20.8 Other forms of angina pectoris
0.667 0.333 0.000
J91 Pleural effusion in conditions classified elsewhere
0.667 0.333 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.666 0.334 0.000
A49 Bacterial infection of unspecified site
0.665 0.335 0.000
J93 Pneumothorax
0.665 0.335 0.000
M47.1 Other spondylosis with myelopathy
0.664 0.336 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.664 0.336 0.000
I24.8 Other forms of acute ischaemic heart disease
0.664 0.336 0.000
Z87 Personal history of other diseases and conditions
0.664 0.336 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.664 0.336 0.000
C60-C63 Malignant neoplasms of male genital organs
0.663 0.337 0.000
C18 Malignant neoplasm of colon
0.663 0.337 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.663 0.337 0.000
I70.0 Atherosclerosis of aorta
0.662 0.338 0.000
I09 Other rheumatic heart diseases
0.662 0.338 0.000
I06 Rheumatic aortic valve diseases
0.662 0.338 0.000
I44.6 Other and unspecified fascicular block
0.661 0.339 0.000
I44.5 Left posterior fascicular block
0.661 0.339 0.000
I44.4 Left anterior fascicular block
0.661 0.339 0.000
I44.3 Other and unspecified atrioventricular block
0.661 0.339 0.000
C15.8 Overlapping lesion of oesophagus
0.660 0.340 0.000
C15.4 Middle third of oesophagus
0.660 0.340 0.000
C15.3 Upper third of oesophagus
0.660 0.340 0.000
C15.2 Abdominal part of oesophagus
0.660 0.340 0.000
C15.1 Thoracic part of oesophagus
0.660 0.340 0.000
C15.0 Cervical part of oesophagus
0.660 0.340 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.659 0.341 0.000
F40 Phobic anxiety disorders
0.659 0.341 0.000
H73.8 Other specified disorders of tympanic membrane
0.659 0.341 0.000
F81 Specific developmental disorders of scholastic skills
0.659 0.341 0.000
I05.0 Mitral stenosis
0.658 0.342 0.000
N42.2 Atrophy of prostate
0.658 0.342 0.000
M54.5 Low back pain
0.657 0.343 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.656 0.344 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.655 0.344 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.654 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.654 0.346 0.000
Y10-Y34 Event of undetermined intent
0.654 0.346 0.000
Y00-Y09 Assault
0.654 0.346 0.000
X85-X99 Assault
0.654 0.346 0.000
X60-X84 Intentional self-harm
0.654 0.346 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.654 0.346 0.000
X50-X57 Overexertion, travel and privation
0.654 0.346 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.346 0.000
X30-X39 Exposure to forces of nature
0.654 0.346 0.000
X20-X29 Contact with venomous animals and plants
0.654 0.346 0.000
X10-X19 Contact with heat and hot substances
0.654 0.346 0.000
X00-X09 Exposure to smoke, fire and flames
0.654 0.346 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.654 0.346 0.000
W75-W84 Other accidental threats to breathing
0.654 0.346 0.000
W65-W74 Accidental drowning and submersion
0.654 0.346 0.000
W50-W64 Exposure to animate mechanical forces
0.654 0.346 0.000
V98-V99 Other and unspecified transport accidents
0.654 0.346 0.000
V95-V97 Air and space transport accidents
0.654 0.346 0.000
V90-V94 Water transport accidents
0.654 0.346 0.000
V80-V89 Other land transport accidents
0.654 0.346 0.000
V70-V79 Bus occupant injured in transport accident
0.654 0.346 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.654 0.346 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.654 0.346 0.000
V40-V49 Car occupant injured in transport accident
0.654 0.346 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.654 0.346 0.000
V20-V29 Motorcycle rider injured in transport accident
0.654 0.346 0.000
V01-V09 Pedestrian injured in transport accident
0.654 0.346 0.000
I42.8 Other cardiomyopathies
0.654 0.346 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.654 0.346 0.000
I42.6 Alcoholic cardiomyopathy
0.654 0.346 0.000
I42.5 Other restrictive cardiomyopathy
0.654 0.346 0.000
I42.4 Endocardial fibroelastosis
0.654 0.346 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.654 0.346 0.000
I42.2 Other hypertrophic cardiomyopathy
0.654 0.346 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.654 0.346 0.000
B37.8 Candidiasis of other sites
0.654 0.346 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.653 0.347 0.000
Z90.5 Acquired absence of kidney
0.653 0.347 0.000
F20 Schizophrenia
0.653 0.347 0.000
F29 Unspecified nonorganic psychosis
0.653 0.347 0.000
S90-S99 Injuries to the ankle and foot
0.651 0.349 0.000
F31.9 Bipolar affective disorder, unspecified
0.651 0.349 0.000
F38 Other mood [affective] disorders
0.650 0.350 0.000
F34 Persistent mood [affective] disorders
0.650 0.350 0.000
F30 Manic episode
0.650 0.350 0.000
F39 Unspecified mood [affective] disorder
0.650 0.350 0.000
Z82.3 Family history of stroke
0.650 0.350 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.650 0.350 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.648 0.352 0.000
E06 Thyroiditis
0.647 0.353 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.647 0.353 0.000
E00 Congenital iodine-deficiency syndrome
0.647 0.353 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.647 0.353 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.647 0.353 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.647 0.353 0.000
M20.0 Deformity of finger(s)
0.647 0.353 0.000
E28 Ovarian dysfunction
0.646 0.354 0.000
M48 Other spondylopathies
0.646 0.354 0.000
A00-A09 Intestinal infectious diseases
0.646 0.354 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.645 0.354 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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