TreeWAS – Variant ID: rs80196851

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I20-I25 Ischaemic heart diseases	0.146	0.854
I25 Chronic ischaemic heart disease	0.145	0.855
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.140	0.860
Chapter XIV Diseases of the genitourinary system	0.140	0.860
Chapter IX Diseases of the circulatory system	0.139	0.861
# Top node	0.139	0.861
I25.8 Other forms of chronic ischaemic heart disease	0.136	0.864
S00-S09 Injuries to the head	0.135	0.865
I25.2 Old myocardial infarction	0.132	0.868
Chapter I Certain infectious and parasitic diseases	0.131	0.869
I25.1 Atherosclerotic heart disease	0.130	0.870
N17-N19 Renal failure	0.130	0.870
I20 Angina pectoris	0.129	0.871
N20-N23 Urolithiasis	0.126	0.874
Chapter XI Diseases of the digestive system	0.126	0.874
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.124	0.876
S01 Open wound of head	0.123	0.877
Chapter XX External causes of morbidity and mortality	0.123	0.877
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.122	0.878
N23 Unspecified renal colic	0.122	0.878
B95-B98 Bacterial, viral and other infectious agents	0.121	0.879
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.121	0.879
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.120	0.880
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.120	0.880
N60-N64 Disorders of breast	0.118	0.882
N18 Chronic renal failure	0.118	0.882
K02 Dental caries	0.117	0.883
I95-I99 Other and unspecified disorders of the circulatory system	0.117	0.883
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.116	0.884
I21 Acute myocardial infarction	0.116	0.884
N70-N77 Inflammatory diseases of female pelvic organs	0.115	0.885
N25-N29 Other disorders of kidney and ureter	0.115	0.885
K02.9 Dental caries, unspecified	0.114	0.886
T90 Sequelae of injuries of head	0.114	0.886
I24 Other acute ischaemic heart diseases	0.114	0.886
S02 Fracture of skull and facial bones	0.114	0.886
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.114	0.886
I05-I09 Chronic rheumatic heart diseases	0.113	0.887
S09 Other and unspecified injuries of head	0.113	0.887
N17 Acute renal failure	0.112	0.888
Chapter VI Diseases of the nervous system	0.112	0.888
I20.8 Other forms of angina pectoris	0.112	0.888
N80-N98 Noninflammatory disorders of female genital tract	0.112	0.888
K22 Other diseases of oesophagus	0.112	0.888
S80-S89 Injuries to the knee and lower leg	0.111	0.889
K01 Embedded and impacted teeth	0.110	0.890
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.109	0.891
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.109	0.891
S06 Intracranial injury	0.109	0.891
K20-K31 Diseases of oesophagus, stomach and duodenum	0.109	0.891
N18.5 Chronic kidney disease, stage 5	0.109	0.891
Chapter XXII Codes for special purposes	0.108	0.892
I20.1 Angina pectoris with documented spasm	0.108	0.892
Chapter XV Pregnancy, childbirth and the puerperium	0.108	0.892
K70-K77 Diseases of liver	0.108	0.892
T79-T79 Certain early complications of trauma	0.107	0.893
T66-T78 Other and unspecified effects of external causes	0.106	0.894
N10-N16 Renal tubulo-interstitial diseases	0.106	0.894
B25-B34 Other viral diseases	0.105	0.895
I23 Certain current complications following acute myocardial infarction	0.105	0.895
I25.6 Silent myocardial ischaemia	0.104	0.895
I25.4 Coronary artery aneurysm	0.104	0.895
I25.3 Aneurysm of heart	0.104	0.895
I25.0 Atherosclerotic cardiovascular disease, so described	0.104	0.895
K31 Other diseases of stomach and duodenum	0.104	0.896
N00-N08 Glomerular diseases	0.103	0.896
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.103	0.897
I25.5 Ischaemic cardiomyopathy	0.103	0.897
S20-S29 Injuries to the thorax	0.102	0.897
K22.7 Barrett's oesophagus	0.102	0.898
Chapter VIII Diseases of the ear and mastoid process	0.102	0.898
N18.3 Chronic kidney disease, stage 3	0.102	0.898
B35-B49 Mycoses	0.102	0.898
I20.0 Unstable angina	0.102	0.898
K22.1 Ulcer of oesophagus	0.102	0.898
S40-S49 Injuries to the shoulder and upper arm	0.102	0.898
K31.8 Other specified diseases of stomach and duodenum	0.102	0.898
T15-T19 Effects of foreign body entering through natural orifice	0.101	0.898
S90-S99 Injuries to the ankle and foot	0.101	0.899
K01.1 Impacted teeth	0.101	0.899
W00-W19 Falls	0.101	0.899
T33-T35 Frostbite	0.101	0.899
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.101	0.899
T26-T28 Burns and corrosions confined to eye and internal organs	0.101	0.899
T20-T25 Burns and corrosions of external body surface, specified by site	0.101	0.899
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.101	0.899
T00-T07 Injuries involving multiple body regions	0.101	0.899
S10-S19 Injuries to the neck	0.101	0.899
S60-S69 Injuries to the wrist and hand	0.101	0.899
S01.0 Open wound of scalp	0.101	0.899
K12 Stomatitis and related lesions	0.100	0.900
I00-I02 Acute rheumatic fever	0.100	0.900
I22 Subsequent myocardial infarction	0.100	0.900
Chapter XVI Certain conditions originating in the perinatal period	0.100	0.900
N72 Inflammatory disease of cervix uteri	0.100	0.900
N17.9 Acute renal failure, unspecified	0.099	0.901
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.099	0.901
N28 Other disorders of kidney and ureter, not elsewhere classified	0.098	0.902
A50-A64 Infections with a predominantly sexual mode of transmission	0.098	0.902
Q60-Q64 Congenital malformations of the urinary system	0.098	0.902
S01.8 Open wound of other parts of head	0.098	0.902
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.098	0.902
K22.2 Oesophageal obstruction	0.098	0.902
S08 Traumatic amputation of part of head	0.097	0.903
S07 Crushing injury of head	0.097	0.903
S05 Injury of eye and orbit	0.097	0.903
S04 Injury of cranial nerves	0.097	0.903
S03 Dislocation, sprain and strain of joints and ligaments of head	0.097	0.903
N89 Other noninflammatory disorders of vagina	0.097	0.903
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.097	0.903
K22.9 Disease of oesophagus, unspecified	0.097	0.903
T90.2 Sequelae of fracture of skull and facial bones	0.097	0.903
N63 Unspecified lump in breast	0.097	0.903
S01.1 Open wound of eyelid and periocular area	0.097	0.903
S01.5 Open wound of lip and oral cavity	0.097	0.903
N97 Female infertility	0.097	0.903
B15-B19 Viral hepatitis	0.096	0.903
I98 Other disorders of circulatory system in diseases classified elsewhere	0.096	0.904
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.096	0.904
S32 Fracture of lumbar spine and pelvis	0.096	0.904
S09.9 Unspecified injury of head	0.096	0.904
N80 Endometriosis	0.096	0.904
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.096	0.904
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.096	0.904
W20-W49 Exposure to inanimate mechanical forces	0.096	0.904
N99-N99 Other disorders of the genitourinary system	0.096	0.904
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.095	0.904
T90.5 Sequelae of intracranial injury	0.095	0.905
K65-K67 Diseases of peritoneum	0.095	0.905
Y60-Y69 Misadventures to patients during surgical and medical care	0.095	0.905
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.095	0.905
Q20-Q28 Congenital malformations of the circulatory system	0.095	0.905
I27 Other pulmonary heart diseases	0.095	0.905
I60-I69 Cerebrovascular diseases	0.095	0.905
B99-B99 Other infectious diseases	0.094	0.906
B90-B94 Sequelae of infectious and parasitic diseases	0.094	0.906
B85-B89 Pediculosis, acariasis and other infestations	0.094	0.906
B65-B83 Helminthiases	0.094	0.906
B50-B64 Protozoal diseases	0.094	0.906
B20-B24 Human immunodeficiency virus [HIV] disease	0.094	0.906
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.094	0.906
A80-A89 Viral infections of the central nervous system	0.094	0.906
A75-A79 Rickettsioses	0.094	0.906
A70-A74 Other diseases caused by chlamydiae	0.094	0.906
A65-A69 Other spirochaetal diseases	0.094	0.906
A20-A28 Certain zoonotic bacterial diseases	0.094	0.906
A15-A19 Tuberculosis	0.094	0.906
O80-O84 Delivery	0.094	0.906
A00-A09 Intestinal infectious diseases	0.094	0.906
I10-I15 Hypertensive diseases	0.094	0.906
S70-S79 Injuries to the hip and thigh	0.094	0.906
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.093	0.906
N76 Other inflammation of vagina and vulva	0.093	0.907
I08 Multiple valve diseases	0.093	0.907
S01.2 Open wound of nose	0.093	0.907
N64 Other disorders of breast	0.093	0.907
K05 Gingivitis and periodontal diseases	0.093	0.907
S81 Open wound of lower leg	0.093	0.907
S30 Superficial injury of abdomen, lower back and pelvis	0.092	0.907
I21.9 Acute myocardial infarction, unspecified	0.092	0.908
N62 Hypertrophy of breast	0.092	0.908
N87 Dysplasia of cervix uteri	0.092	0.908
T81 Complications of procedures, not elsewhere classified	0.092	0.908
I21.0 Acute transmural myocardial infarction of anterior wall	0.092	0.908
N40-N51 Diseases of male genital organs	0.092	0.908
S02.5 Fracture of tooth	0.091	0.908
I26 Pulmonary embolism	0.091	0.909
I95 Hypotension	0.091	0.909
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.091	0.909
O20-O29 Other maternal disorders predominantly related to pregnancy	0.091	0.909
G90-G99 Other disorders of the nervous system	0.091	0.909
N22 Calculus of urinary tract in diseases classified elsewhere	0.090	0.909
K07 Dentofacial anomalies [including malocclusion]	0.090	0.910
N95 Menopausal and other perimenopausal disorders	0.090	0.910
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.090	0.910
N93 Other abnormal uterine and vaginal bleeding	0.090	0.910
Q50-Q56 Congenital malformations of genital organs	0.090	0.910
K86 Other diseases of pancreas	0.090	0.910
T90.9 Sequelae of unspecified injury of head	0.090	0.910
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.090	0.910
T98 Sequelae of other and unspecified effects of external causes	0.089	0.910
T95 Sequelae of burns, corrosions and frostbite	0.089	0.910
T94 Sequelae of injuries involving multiple and unspecified body regions	0.089	0.910
T92 Sequelae of injuries of upper limb	0.089	0.910
T91 Sequelae of injuries of neck and trunk	0.089	0.910
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.089	0.910
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.089	0.910
K26 Duodenal ulcer	0.089	0.911
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.089	0.911
S02.4 Fracture of malar and maxillary bones	0.089	0.911
K74 Fibrosis and cirrhosis of liver	0.089	0.911
Chapter II Neoplasms	0.089	0.911
K72 Hepatic failure, not elsewhere classified	0.088	0.912
S01.7 Multiple open wounds of head	0.088	0.912
S01.4 Open wound of cheek and temporomandibular area	0.088	0.912
S01.3 Open wound of ear	0.088	0.912
N18.0 End-stage renal disease	0.088	0.912
K11 Diseases of salivary glands	0.088	0.912
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.088	0.912
Y35-Y36 Legal intervention and operations of war	0.088	0.912
Y10-Y34 Event of undetermined intent	0.088	0.912
Y00-Y09 Assault	0.088	0.912
X85-X99 Assault	0.088	0.912
X58-X59 Accidental exposure to other and unspecified factors	0.088	0.912
X50-X57 Overexertion, travel and privation	0.088	0.912
X40-X49 Accidental poisoning by and exposure to noxious substances	0.088	0.912
X30-X39 Exposure to forces of nature	0.088	0.912
X20-X29 Contact with venomous animals and plants	0.088	0.912
X10-X19 Contact with heat and hot substances	0.088	0.912
X00-X09 Exposure to smoke, fire and flames	0.088	0.912
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.088	0.912
W75-W84 Other accidental threats to breathing	0.088	0.912
W65-W74 Accidental drowning and submersion	0.088	0.912
W50-W64 Exposure to animate mechanical forces	0.088	0.912
V98-V99 Other and unspecified transport accidents	0.088	0.912
V95-V97 Air and space transport accidents	0.088	0.912
V90-V94 Water transport accidents	0.088	0.912
V80-V89 Other land transport accidents	0.088	0.912
V70-V79 Bus occupant injured in transport accident	0.088	0.912
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.088	0.912
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.088	0.912
V40-V49 Car occupant injured in transport accident	0.088	0.912
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.088	0.912
V01-V09 Pedestrian injured in transport accident	0.088	0.912
I24.9 Acute ischaemic heart disease, unspecified	0.088	0.912
N28.8 Other specified disorders of kidney and ureter	0.088	0.912
S50-S59 Injuries to the elbow and forearm	0.088	0.912
K10 Other diseases of jaws	0.087	0.912
K09 Cysts of oral region, not elsewhere classified	0.087	0.912
K06 Other disorders of gingiva and edentulous alveolar ridge	0.087	0.912
K03 Other diseases of hard tissues of teeth	0.087	0.912
K00 Disorders of tooth development and eruption	0.087	0.912
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.087	0.912
N89.8 Other specified noninflammatory disorders of vagina	0.087	0.913
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.087	0.913
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.087	0.913
S06.6 Traumatic subarachnoid haemorrhage	0.087	0.913
I70-I79 Diseases of arteries, arterioles and capillaries	0.087	0.913
N21 Calculus of lower urinary tract	0.087	0.913
O85-O92 Complications predominantly related to the puerperium	0.087	0.913
V20-V29 Motorcycle rider injured in transport accident	0.087	0.913
T93 Sequelae of injuries of lower limb	0.086	0.913
B25 Cytomegaloviral disease	0.086	0.913
N70 Salpingitis and oophoritis	0.086	0.914
T88 Other complications of surgical and medical care, not elsewhere classified	0.086	0.914
N85 Other noninflammatory disorders of uterus, except cervix	0.086	0.914
Y43 Primarily systemic agents	0.086	0.914
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.086	0.914
S37 Injury of urinary and pelvic organs	0.086	0.914
S36 Injury of intra-abdominal organs	0.086	0.914
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.086	0.914
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.086	0.914
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.086	0.914
S31 Open wound of abdomen, lower back and pelvis	0.086	0.914
N97.9 Female infertility, unspecified	0.086	0.914
X60-X84 Intentional self-harm	0.086	0.914
I21.2 Acute transmural myocardial infarction of other sites	0.086	0.914
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.086	0.914
N88 Other noninflammatory disorders of cervix uteri	0.086	0.914
C15-C26 Malignant neoplasms of digestive organs	0.086	0.914
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.086	0.914
Q80-Q89 Other congenital malformations	0.086	0.914
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.086	0.914
Q38-Q45 Other congenital malformations of the digestive system	0.086	0.914
Q35-Q37 Cleft lip and cleft palate	0.086	0.914
Q30-Q34 Congenital malformations of the respiratory system	0.086	0.914
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.086	0.914
Q00-Q07 Congenital malformations of the nervous system	0.086	0.914
W19 Unspecified fall	0.086	0.914
O80 Single spontaneous delivery	0.086	0.914
N19 Unspecified renal failure	0.085	0.915
I25.9 Chronic ischaemic heart disease, unspecified	0.085	0.915
O60-O75 Complications of labour and delivery	0.085	0.915
S89 Other and unspecified injuries of lower leg	0.085	0.915
N13 Obstructive and reflux uropathy	0.085	0.915
N18.8 Other chronic renal failure	0.085	0.915
N18.2 Chronic kidney disease, stage 2	0.085	0.915
N18.1 Chronic kidney disease, stage 1	0.085	0.915
S02.2 Fracture of nasal bones	0.085	0.915
K12.1 Other forms of stomatitis	0.085	0.915
G62 Other polyneuropathies	0.085	0.915
N61 Inflammatory disorders of breast	0.084	0.915
I21.1 Acute transmural myocardial infarction of inferior wall	0.084	0.915
G70-G73 Diseases of myoneural junction and muscle	0.084	0.916
K02.8 Other dental caries	0.084	0.916
K02.5 Caries with pulp exposure	0.084	0.916
K02.4 Odontoclasia	0.084	0.916
K02.3 Arrested dental caries	0.084	0.916
K02.2 Caries of cementum	0.084	0.916
K02.1 Caries of dentin	0.084	0.916
K02.0 Caries limited to enamel	0.084	0.916
T80 Complications following infusion, transfusion and therapeutic injection	0.084	0.916
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.084	0.916
I99 Other and unspecified disorders of circulatory system	0.084	0.916
H80-H83 Diseases of inner ear	0.084	0.916
K22.4 Dyskinesia of oesophagus	0.084	0.916
I28 Other diseases of pulmonary vessels	0.084	0.916
T79 Certain early complications of trauma, not elsewhere classified	0.084	0.916
I21.X Presumed acute myicardial infaction (unconfirmed)	0.083	0.916
I21.3 Acute transmural myocardial infarction of unspecified site	0.083	0.916
G30-G32 Other degenerative diseases of the nervous system	0.083	0.917
C15 Malignant neoplasm of oesophagus	0.083	0.917
N90 Other noninflammatory disorders of vulva and perineum	0.083	0.917
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.083	0.917
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.083	0.917
N27 Small kidney of unknown cause	0.083	0.917
N25 Disorders resulting from impaired renal tubular function	0.083	0.917
N26 Unspecified contracted kidney	0.083	0.917
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.083	0.917
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.083	0.917
N71 Inflammatory disease of uterus, except cervix	0.083	0.917
I12 Hypertensive renal disease	0.083	0.917
B97 Viral agents as the cause of diseases classified to other chapters	0.083	0.917
S00 Superficial injury of head	0.082	0.917
S01.9 Open wound of head, part unspecified	0.082	0.918
N05 Unspecified nephritic syndrome	0.082	0.918
S80 Superficial injury of lower leg	0.082	0.918
S06.2 Diffuse brain injury	0.082	0.918
K31.5 Obstruction of duodenum	0.082	0.918
I07 Rheumatic tricuspid valve diseases	0.082	0.918
T90.8 Sequelae of other specified injuries of head	0.082	0.918
T90.4 Sequelae of injury of eye and orbit	0.082	0.918
T90.3 Sequelae of injury of cranial nerves	0.082	0.918
T90.1 Sequelae of open wound of head	0.082	0.918
T90.0 Sequelae of superficial injury of head	0.082	0.918
H60-H62 Diseases of external ear	0.082	0.918
I24.1 Dressler's syndrome	0.082	0.918
I98.2 Oesophageal varices in diseases classified elsewhere	0.082	0.918
S02.9 Fracture of skull and facial bones, part unspecified	0.082	0.918
S02.8 Fractures of other skull and facial bones	0.082	0.918
S02.7 Multiple fractures involving skull and facial bones	0.082	0.918
S02.6 Fracture of mandible	0.082	0.918
S02.3 Fracture of orbital floor	0.082	0.918
S02.1 Fracture of base of skull	0.082	0.918
S02.0 Fracture of vault of skull	0.082	0.918
Y51 Drugs primarily affecting the autonomic nervous system	0.082	0.918
K70 Alcoholic liver disease	0.081	0.918
T78 Adverse effects, not elsewhere classified	0.081	0.918
V10-V19 Pedal cyclist injured in transport accident	0.081	0.919
B37 Candidiasis	0.081	0.919
I09 Other rheumatic heart diseases	0.081	0.919
I06 Rheumatic aortic valve diseases	0.081	0.919
I05 Rheumatic mitral valve diseases	0.081	0.919
Y84.8 Other medical procedures	0.081	0.919
S09.8 Other specified injuries of head	0.081	0.919
S09.7 Multiple injuries of head	0.081	0.919
S09.2 Traumatic rupture of ear drum	0.081	0.919
S09.1 Injury of muscle and tendon of head	0.081	0.919
S09.0 Injury of blood vessels of head, not elsewhere classified	0.081	0.919
G80-G83 Cerebral palsy and other paralytic syndromes	0.081	0.919
N17.8 Other acute renal failure	0.081	0.919
N17.2 Acute renal failure with medullary necrosis	0.081	0.919
N17.1 Acute renal failure with acute cortical necrosis	0.081	0.919
N17.0 Acute renal failure with tubular necrosis	0.081	0.919
G00-G09 Inflammatory diseases of the central nervous system	0.081	0.919
G20-G26 Extrapyramidal and movement disorders	0.081	0.919
N48 Other disorders of penis	0.080	0.920
N98 Complications associated with artificial fertilisation	0.080	0.920
N91 Absent, scanty and rare menstruation	0.080	0.920
N82 Fistulae involving female genital tract	0.080	0.920
N96 Habitual aborter	0.080	0.920
K31.9 Disease of stomach and duodenum, unspecified	0.080	0.920
S20 Superficial injury of thorax	0.080	0.920
N10 Acute tubulo-interstitial nephritis	0.080	0.920
S81.9 Open wound of lower leg, part unspecified	0.080	0.920
K22.5 Diverticulum of oesophagus, acquired	0.080	0.920
K22.3 Perforation of oesophagus	0.080	0.920
K22.0 Achalasia of cardia	0.080	0.920
O80.0 Spontaneous vertex delivery	0.080	0.920
S82 Fracture of lower leg, including ankle	0.080	0.920
S88 Traumatic amputation of lower leg	0.080	0.920
S87 Crushing injury of lower leg	0.080	0.920
S86 Injury of muscle and tendon at lower leg level	0.080	0.920
S85 Injury of blood vessels at lower leg level	0.080	0.920
S84 Injury of nerves at lower leg level	0.080	0.920
B07 Viral warts	0.080	0.920
G61 Inflammatory polyneuropathy	0.080	0.920
N04 Nephrotic syndrome	0.080	0.920
K50-K52 Noninfective enteritis and colitis	0.080	0.920
N85.8 Other specified noninflammatory disorders of uterus	0.079	0.921
Q60 Renal agenesis and other reduction defects of kidney	0.079	0.921
I27.2 Other secondary pulmonary hypertension	0.079	0.921
N60 Benign mammary dysplasia	0.079	0.921
K01.0 Embedded teeth	0.079	0.921
K31.1 Adult hypertrophic pyloric stenosis	0.079	0.921
K86.8 Other specified diseases of pancreas	0.079	0.921
T87 Complications peculiar to reattachment and amputation	0.079	0.921
T86 Failure and rejection of transplanted organs and tissues	0.079	0.921
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.078	0.921
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.078	0.921
Y40 Systemic antibiotics	0.078	0.922
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.078	0.922
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.078	0.922
A04 Other bacterial intestinal infections	0.078	0.922
I08.0 Disorders of both mitral and aortic valves	0.078	0.922
N08 Glomerular disorders in diseases classified elsewhere	0.078	0.922
S06.9 Intracranial injury, unspecified	0.078	0.922
S06.8 Other intracranial injuries	0.078	0.922
S06.7 Intracranial injury with prolonged coma	0.078	0.922
S06.4 Epidural haemorrhage	0.078	0.922
S06.3 Focal brain injury	0.078	0.922
S06.1 Traumatic cerebral oedema	0.078	0.922
S06.0 Concussion	0.078	0.922
K28 Gastrojejunal ulcer	0.078	0.922
K23 Disorders of oesophagus in diseases classified elsewhere	0.078	0.922
N95.8 Other specified menopausal and perimenopausal disorders	0.078	0.922
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.078	0.922
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.078	0.922
S62 Fracture at wrist and hand level	0.078	0.922
K77 Liver disorders in diseases classified elsewhere	0.077	0.922
K75 Other inflammatory liver diseases	0.077	0.922
K73 Chronic hepatitis, not elsewhere classified	0.077	0.922
K71 Toxic liver disease	0.077	0.922
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.077	0.923
K27 Peptic ulcer, site unspecified	0.077	0.923
N41 Inflammatory diseases of prostate	0.077	0.923
S06.5 Traumatic subdural haemorrhage	0.077	0.923
C18 Malignant neoplasm of colon	0.077	0.923
S66 Injury of muscle and tendon at wrist and hand level	0.077	0.923
Q21 Congenital malformations of cardiac septa	0.077	0.923
A30-A49 Other bacterial diseases	0.077	0.923
S32.5 Fracture of pubis	0.077	0.923
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.077	0.923
B34 Viral infection of unspecified site	0.076	0.923
D37-D48 Neoplasms of uncertain or unknown behaviour	0.076	0.923
K14 Diseases of tongue	0.076	0.924
T81.4 Infection following a procedure, not elsewhere classified	0.076	0.924
T75 Effects of other external causes	0.076	0.924
T74 Maltreatment syndromes	0.076	0.924
T73 Effects of other deprivation	0.076	0.924
T70 Effects of air pressure and water pressure	0.076	0.924
T69 Other effects of reduced temperature	0.076	0.924
T67 Effects of heat and light	0.076	0.924
T71 Asphyxiation	0.076	0.924
T68 Hypothermia	0.076	0.924
T66 Unspecified effects of radiation	0.076	0.924
Y52 Agents primarily affecting the cardiovascular system	0.076	0.924
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.076	0.924
N15 Other renal tubulo-interstitial diseases	0.076	0.924
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.076	0.924
N11 Chronic tubulo-interstitial nephritis	0.076	0.924
N87.1 Moderate cervical dysplasia	0.076	0.924
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.076	0.924
B33 Other viral diseases, not elsewhere classified	0.076	0.924
B30 Viral conjunctivitis	0.076	0.924
B27 Infectious mononucleosis	0.076	0.924
B26 Mumps	0.076	0.924
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.076	0.924
S02.50 Fracture of tooth (closed)	0.076	0.924
O21 Excessive vomiting in pregnancy	0.076	0.924
N80.0 Endometriosis of uterus	0.076	0.924
C15.5 Lower third of oesophagus	0.075	0.924
K13 Other diseases of lip and oral mucosa	0.075	0.924
N80.9 Endometriosis, unspecified	0.075	0.925
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.075	0.925
S40 Superficial injury of shoulder and upper arm	0.075	0.925
I23.8 Other current complications following acute myocardial infarction	0.075	0.925
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.075	0.925
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.075	0.925
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.075	0.925
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.075	0.925
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.075	0.925
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.075	0.925
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.075	0.925
S32.7 Multiple fractures of lumbar spine and pelvis	0.075	0.925
C15.9 Oesophagus, unspecified	0.075	0.925
Y84.2 Radiological procedure and radiotherapy	0.075	0.925
G40-G47 Episodic and paroxysmal disorders	0.075	0.925
I12.0 Hypertensive renal disease with renal failure	0.075	0.925
K31.6 Fistula of stomach and duodenum	0.075	0.925
K31.4 Gastric diverticulum	0.075	0.925
K31.3 Pylorospasm, not elsewhere classified	0.075	0.925
K31.2 Hourglass stricture and stenosis of stomach	0.075	0.925
K31.0 Acute dilatation of stomach	0.075	0.925
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.075	0.925
N76.4 Abscess of vulva	0.075	0.925
Q61 Cystic kidney disease	0.074	0.925
N80.3 Endometriosis of pelvic peritoneum	0.075	0.925
K74.6 Other and unspecified cirrhosis of liver	0.074	0.925
K72.9 Hepatic failure, unspecified	0.074	0.925
N07 Hereditary nephropathy, not elsewhere classified	0.074	0.926
N06 Isolated proteinuria with specified morphological lesion	0.074	0.926
N01 Rapidly progressive nephritic syndrome	0.074	0.926
N00 Acute nephritic syndrome	0.074	0.926
T63 Toxic effect of contact with venomous animals	0.074	0.926
I27.9 Pulmonary heart disease, unspecified	0.074	0.926
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.074	0.926
Y59 Other and unspecified vaccines and biological substances	0.074	0.926
Y58 Bacterial vaccines	0.074	0.926
Y57 Other and unspecified drugs and medicaments	0.074	0.926
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.074	0.926
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.074	0.926
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.074	0.926
Y53 Agents primarily affecting the gastro-intestinal system	0.074	0.926
Y50 Central nervous system stimulants, not elsewhere classified	0.074	0.926
Y49 Psychotropic drugs, not elsewhere classified	0.074	0.926
Y48 Anaesthetics and therapeutic gases	0.074	0.926
Y47 Sedatives, hypnotics and antianxiety drugs	0.074	0.926
Y46 Antiepileptics and anti-Parkinsonism drugs	0.074	0.926
Y44 Agents primarily affecting blood constituents	0.074	0.926

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations