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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80249880
log Bayes Factor = 15.9037
Chromosome 2   position 149,827,104  (GRCh37) Explore rs80249880 on Ensembl!
Variant rs80249880 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
F41 Other anxiety disorders
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
G40-G47 Episodic and paroxysmal disorders
0.988 0.012 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.983 0.017 0.000
F31 Bipolar affective disorder
0.978 0.022 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.977 0.023 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.975 0.025 0.000
G90-G99 Other disorders of the nervous system
0.972 0.028 0.000
F41.9 Anxiety disorder, unspecified
0.969 0.031 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.968 0.032 0.000
F32 Depressive episode
0.965 0.035 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.963 0.037 0.000
F33 Recurrent depressive disorder
0.962 0.038 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.956 0.044 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.955 0.045 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.953 0.047 0.000
G40 Epilepsy
0.953 0.047 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.942 0.058 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.938 0.062 0.000
F31.9 Bipolar affective disorder, unspecified
0.938 0.062 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.936 0.064 0.000
H53-H54 Visual disturbances and blindness
0.929 0.071 0.000
H30-H36 Disorders of choroid and retina
0.928 0.072 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.927 0.073 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.926 0.074 0.000
O60-O75 Complications of labour and delivery
0.920 0.080 0.000
Chapter XX External causes of morbidity and mortality
0.919 0.081 0.000
H04 Disorders of lachrymal system
0.919 0.081 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.916 0.084 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.915 0.085 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.911 0.089 0.000
B95-B98 Bacterial, viral and other infectious agents
0.911 0.089 0.000
F33.9 Recurrent depressive disorder, unspecified
0.906 0.094 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.906 0.094 0.000
H10-H13 Disorders of conjunctiva
0.892 0.108 0.000
F32.1 Moderate depressive episode
0.891 0.109 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.890 0.110 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.887 0.113 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.886 0.114 0.000
T66-T78 Other and unspecified effects of external causes
0.884 0.116 0.000
H02 Other disorders of eyelid
0.883 0.117 0.000
F41.2 Mixed anxiety and depressive disorder
0.882 0.118 0.000
B07 Viral warts
0.880 0.120 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.878 0.122 0.000
H53 Visual disturbances
0.877 0.123 0.000
G95 Other diseases of spinal cord
0.875 0.125 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.874 0.126 0.000
E70-E90 Metabolic disorders
0.871 0.129 0.000
A00-A09 Intestinal infectious diseases
0.869 0.131 0.000
F48 Other neurotic disorders
0.869 0.131 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.869 0.131 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.868 0.132 0.000
G90 Disorders of autonomic nervous system
0.866 0.134 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.862 0.138 0.000
E86 Volume depletion
0.859 0.141 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.857 0.143 0.000
H53.8 Other visual disturbances
0.856 0.144 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.856 0.144 0.000
Chapter XXII Codes for special purposes
0.856 0.144 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.849 0.151 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.849 0.151 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.849 0.151 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.848 0.152 0.000
F10.2 Dependence syndrome
0.848 0.152 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.848 0.152 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.847 0.153 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.844 0.156 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.842 0.158 0.000
H36 Retinal disorders in diseases classified elsewhere
0.841 0.159 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.840 0.160 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.837 0.163 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.836 0.164 0.000
H55-H59 Other disorders of eye and adnexa
0.833 0.167 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.832 0.168 0.000
S90-S99 Injuries to the ankle and foot
0.830 0.170 0.000
G70-G73 Diseases of myoneural junction and muscle
0.829 0.171 0.000
Chapter II Neoplasms
0.825 0.175 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.822 0.178 0.000
S70-S79 Injuries to the hip and thigh
0.821 0.179 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.821 0.179 0.000
G40.9 Epilepsy, unspecified
0.820 0.180 0.000
E10-E14 Diabetes mellitus
0.819 0.181 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.818 0.182 0.000
A04 Other bacterial intestinal infections
0.818 0.182 0.000
Chapter IX Diseases of the circulatory system
0.816 0.184 0.000
F10.1 Harmful use
0.815 0.185 0.000
L82 Seborrhoeic keratosis
0.814 0.186 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.813 0.187 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.812 0.187 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.810 0.190 0.000
O23 Infections of genito-urinary tract in pregnancy
0.809 0.191 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.808 0.192 0.000
F10.3 Withdrawal state
0.808 0.192 0.000
G30-G32 Other degenerative diseases of the nervous system
0.807 0.193 0.000
G62 Other polyneuropathies
0.806 0.194 0.000
H53.9 Visual disturbance, unspecified
0.806 0.194 0.000
H20 Iridocyclitis
0.806 0.194 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.805 0.195 0.000
Q23 Congenital malformations of aortic and mitral valves
0.803 0.197 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.803 0.197 0.000
F29 Unspecified nonorganic psychosis
0.802 0.198 0.000
H02.8 Other specified disorders of eyelid
0.802 0.198 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.802 0.198 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.801 0.199 0.000
H02.5 Other disorders affecting eyelid function
0.800 0.200 0.000
F43 Reaction to severe stress, and adjustment disorders
0.800 0.200 0.000
O20 Haemorrhage in early pregnancy
0.800 0.200 0.000
G40.8 Other epilepsy
0.800 0.200 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.798 0.202 0.000
H11 Other disorders of conjunctiva
0.798 0.202 0.000
Q80-Q89 Other congenital malformations
0.798 0.202 0.000
T42.4 Benzodiazepines
0.795 0.205 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.795 0.205 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.794 0.206 0.000
O26.8 Other specified pregnancy-related conditions
0.792 0.208 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.792 0.208 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.791 0.209 0.000
M65-M68 Disorders of synovium and tendon
0.785 0.215 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.784 0.216 0.000
A30-A49 Other bacterial diseases
0.782 0.218 0.000
H04.1 Other disorders of lachrymal gland
0.780 0.220 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.780 0.220 0.000
H36.0 Diabetic retinopathy
0.779 0.221 0.000
F80-F89 Disorders of psychological development
0.778 0.222 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.778 0.222 0.000
E10 Insulin-dependent diabetes mellitus
0.777 0.223 0.000
F48.0 Neurasthenia
0.777 0.223 0.000
F41.1 Generalised anxiety disorder
0.776 0.224 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.776 0.224 0.000
F39 Unspecified mood [affective] disorder
0.775 0.225 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.775 0.225 0.000
F10.5 Psychotic disorder
0.773 0.226 0.000
S10-S19 Injuries to the neck
0.773 0.227 0.000
O21 Excessive vomiting in pregnancy
0.773 0.227 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.773 0.227 0.000
A04.8 Other specified bacterial intestinal infections
0.770 0.230 0.000
I95 Hypotension
0.769 0.231 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.769 0.231 0.000
W50-W64 Exposure to animate mechanical forces
0.767 0.233 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.767 0.233 0.000
Q21 Congenital malformations of cardiac septa
0.765 0.235 0.000
B00 Herpesviral [herpes simplex] infections
0.765 0.235 0.000
T78 Adverse effects, not elsewhere classified
0.764 0.236 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.764 0.236 0.000
H34 Retinal vascular occlusions
0.764 0.236 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.763 0.237 0.000
F22 Persistent delusional disorders
0.761 0.239 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.761 0.239 0.000
M67 Other disorders of synovium and tendon
0.761 0.239 0.000
G45.4 Transient global amnesia
0.761 0.239 0.000
C79 Secondary malignant neoplasm of other sites
0.760 0.240 0.000
G93 Other disorders of brain
0.758 0.242 0.000
G95.2 Cord compression, unspecified
0.758 0.242 0.000
O62 Abnormalities of forces of labour
0.758 0.242 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.757 0.243 0.000
S20-S29 Injuries to the thorax
0.757 0.243 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.757 0.243 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.757 0.243 0.000
G82 Paraplegia and tetraplegia
0.755 0.244 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.755 0.245 0.000
H01 Other inflammation of eyelid
0.755 0.245 0.000
G91 Hydrocephalus
0.753 0.247 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.753 0.247 0.000
F32.9 Depressive episode, unspecified
0.751 0.249 0.000
Y40 Systemic antibiotics
0.751 0.249 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.751 0.249 0.000
F10.0 Acute intoxication
0.751 0.249 0.000
L03 Cellulitis
0.751 0.249 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.750 0.250 0.000
O24 Diabetes mellitus in pregnancy
0.749 0.251 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.749 0.251 0.000
G90.2 Horner's syndrome
0.748 0.252 0.000
M67.8 Other specified disorders of synovium and tendon
0.748 0.252 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.747 0.253 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.746 0.253 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.743 0.257 0.000
H16 Keratitis
0.741 0.259 0.000
T82.3 Mechanical complication of other vascular grafts
0.740 0.260 0.000
H21 Other disorders of iris and ciliary body
0.739 0.261 0.000
L89 Decubitus ulcer
0.739 0.261 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.739 0.261 0.000
T43.2 Other and unspecified antidepressants
0.738 0.262 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.738 0.262 0.000
D00-D09 In situ neoplasms
0.738 0.262 0.000
S50-S59 Injuries to the elbow and forearm
0.737 0.263 0.000
Q27 Other congenital malformations of peripheral vascular system
0.737 0.263 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.736 0.264 0.000
F42 Obsessive-compulsive disorder
0.733 0.267 0.000
G62.8 Other specified polyneuropathies
0.732 0.268 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.732 0.268 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.731 0.269 0.000
I71 Aortic aneurysm and dissection
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
O61 Failed induction of labour
0.729 0.271 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.728 0.272 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.728 0.272 0.000
H05 Disorders of orbit
0.723 0.277 0.000
Q23.1 Congenital insufficiency of aortic valve
0.722 0.278 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.722 0.278 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.721 0.279 0.000
L20-L30 Dermatitis and eczema
0.720 0.280 0.000
F32.0 Mild depressive episode
0.720 0.280 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.720 0.280 0.000
H02.0 Entropion and trichiasis of eyelid
0.719 0.281 0.000
I30-I52 Other forms of heart disease
0.719 0.281 0.000
Chapter XXI Factors influencing health status and contact with health services
0.718 0.282 0.000
T87 Complications peculiar to reattachment and amputation
0.718 0.282 0.000
I95.1 Orthostatic hypotension
0.718 0.282 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
F34 Persistent mood [affective] disorders
0.717 0.283 0.000
F30 Manic episode
0.717 0.283 0.000
E78.5 Hyperlipidaemia, unspecified
0.717 0.283 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.716 0.284 0.000
F44 Dissociative [conversion] disorders
0.715 0.285 0.000
S91 Open wound of ankle and foot
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
E85 Amyloidosis
0.714 0.286 0.000
G70 Myasthenia gravis and other myoneural disorders
0.714 0.286 0.000
A04.5 Campylobacter enteritis
0.714 0.286 0.000
O00-O08 Pregnancy with abortive outcome
0.713 0.287 0.000
T86 Failure and rejection of transplanted organs and tissues
0.713 0.287 0.000
F41.8 Other specified anxiety disorders
0.712 0.288 0.000
F41.3 Other mixed anxiety disorders
0.712 0.288 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.712 0.288 0.000
Z60 Problems related to social environment
0.712 0.288 0.000
T92 Sequelae of injuries of upper limb
0.711 0.289 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.711 0.289 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.710 0.290 0.000
E10.3 With ophthalmic complications
0.710 0.290 0.000
Y52 Agents primarily affecting the cardiovascular system
0.709 0.290 0.000
T68 Hypothermia
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.709 0.291 0.000
C51-C58 Malignant neoplasms of female genital organs
0.709 0.291 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.291 0.000
C45 Mesothelioma
0.708 0.292 0.000
G41 Status epilepticus
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.707 0.292 0.000
Z60.2 Living alone
0.707 0.293 0.000
Q28 Other congenital malformations of circulatory system
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.704 0.296 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.703 0.297 0.000
S32 Fracture of lumbar spine and pelvis
0.703 0.297 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.703 0.297 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.702 0.298 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
F31.8 Other bipolar affective disorders
0.701 0.299 0.000
F31.7 Bipolar affective disorder, currently in remission
0.701 0.299 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.701 0.299 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.701 0.299 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.701 0.299 0.000
F23 Acute and transient psychotic disorders
0.700 0.300 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.700 0.300 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.699 0.300 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.699 0.301 0.000
H43-H45 Disorders of vitreous body and globe
0.699 0.301 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.699 0.301 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.699 0.301 0.000
G45.0 Vertebro-basilar artery syndrome
0.699 0.301 0.000
G58 Other mononeuropathies
0.699 0.301 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.697 0.303 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
G92 Toxic encephalopathy
0.697 0.303 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.696 0.304 0.000
F99-F99 Unspecified mental disorder
0.696 0.304 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.306 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.306 0.000
O20.0 Threatened abortion
0.694 0.306 0.000
M91-M94 Chondropathies
0.694 0.306 0.000
M60-M63 Disorders of muscles
0.693 0.307 0.000
O73 Retained placenta and membranes, without haemorrhage
0.692 0.307 0.000
F60-F69 Disorders of adult personality and behaviour
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.692 0.308 0.000
F32.8 Other depressive episodes
0.692 0.308 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.691 0.309 0.000
H33 Retinal detachments and breaks
0.691 0.309 0.000
O29 Complications of anaesthesia during pregnancy
0.690 0.309 0.000
O28 Abnormal findings on antenatal screening of mother
0.690 0.309 0.000
O22 Venous complications in pregnancy
0.690 0.309 0.000
O25 Malnutrition in pregnancy
0.690 0.309 0.000
F33.8 Other recurrent depressive disorders
0.690 0.310 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.690 0.310 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.690 0.310 0.000
H17 Corneal scars and opacities
0.689 0.311 0.000
H31 Other disorders of choroid
0.688 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.687 0.313 0.000
I95.0 Idiopathic hypotension
0.687 0.313 0.000
Chapter VIII Diseases of the ear and mastoid process
0.687 0.313 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.687 0.313 0.000
Y48 Anaesthetics and therapeutic gases
0.687 0.313 0.000
Q00-Q07 Congenital malformations of the nervous system
0.686 0.314 0.000
G90.3 Multisystem degeneration
0.686 0.314 0.000
F43.1 Posttraumatic stress disorder
0.686 0.314 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.685 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.685 0.315 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.685 0.315 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.685 0.315 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.685 0.315 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.685 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.685 0.315 0.000
F11 Mental and behavioural disorders due to use of opioids
0.685 0.315 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.685 0.315 0.000
G95.8 Other specified diseases of spinal cord
0.685 0.315 0.000
O23.5 Infections of the genital tract in pregnancy
0.685 0.315 0.000
H10 Conjunctivitis
0.684 0.315 0.000
H20.9 Iridocyclitis, unspecified
0.684 0.316 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.683 0.316 0.000
T43.9 Psychotropic drug, unspecified
0.683 0.317 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.683 0.317 0.000
T43.6 Psychostimulants with abuse potential
0.683 0.317 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.683 0.317 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.683 0.317 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.683 0.317 0.000
G40.5 Special epileptic syndromes
0.683 0.317 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.683 0.317 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.683 0.317 0.000
M70-M79 Other soft tissue disorders
0.683 0.317 0.000
H11.0 Pterygium
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.683 0.317 0.000
I95.2 Hypotension due to drugs
0.683 0.317 0.000
M80-M85 Disorders of bone density and structure
0.682 0.318 0.000
E10.5 With peripheral circulatory complications
0.682 0.318 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.682 0.318 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.681 0.319 0.000
T45.5 Anticoagulants
0.681 0.319 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.320 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.680 0.320 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.679 0.321 0.000
X60-X84 Intentional self-harm
0.679 0.321 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.679 0.321 0.000
Y00-Y09 Assault
0.678 0.322 0.000
G62.0 Drug-induced polyneuropathy
0.678 0.322 0.000
T91 Sequelae of injuries of neck and trunk
0.677 0.323 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.676 0.323 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
I05-I09 Chronic rheumatic heart diseases
0.676 0.324 0.000
H54 Blindness and low vision
0.676 0.324 0.000
H04.8 Other disorders of lachrymal system
0.675 0.324 0.000
F10.9 Unspecified mental and behavioural disorder
0.675 0.325 0.000
F10.8 Other mental and behavioural disorders
0.675 0.325 0.000
F10.7 Residual and late-onset psychotic disorder
0.675 0.325 0.000
F10.6 Amnesic syndrome
0.675 0.325 0.000
F10.4 Withdrawal state with delirium
0.675 0.325 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.675 0.325 0.000
I34 Nonrheumatic mitral valve disorders
0.673 0.327 0.000
B06 Rubella [German measles]
0.673 0.327 0.000
B05 Measles
0.673 0.327 0.000
B01 Varicella [chickenpox]
0.673 0.327 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.673 0.327 0.000
B04 Monkeypox
0.673 0.327 0.000
B03 Smallpox
0.673 0.327 0.000
C56 Malignant neoplasm of ovary
0.673 0.327 0.000
O85-O92 Complications predominantly related to the puerperium
0.672 0.328 0.000
B02 Zoster [herpes zoster]
0.672 0.328 0.000
O72 Postpartum haemorrhage
0.671 0.328 0.000
D06 Carcinoma in situ of cervix uteri
0.671 0.329 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.671 0.329 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.671 0.329 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.671 0.329 0.000
T42.3 Barbiturates
0.671 0.329 0.000
T42.2 Succinimides and oxazolidinediones
0.671 0.329 0.000
T42.1 Iminostilbenes
0.671 0.329 0.000
T42.0 Hydantoin derivatives
0.671 0.329 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.671 0.329 0.000
V40-V49 Car occupant injured in transport accident
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y57 Other and unspecified drugs and medicaments
0.670 0.330 0.000
C34 Malignant neoplasm of bronchus and lung
0.670 0.330 0.000
H18 Other disorders of cornea
0.669 0.331 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.668 0.331 0.000
V80-V89 Other land transport accidents
0.668 0.332 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.667 0.333 0.000
T21 Burn and corrosion of trunk
0.667 0.333 0.000
H55 Nystagmus and other irregular eye movements
0.667 0.333 0.000
G95.1 Vascular myelopathies
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.665 0.335 0.000
H30 Chorioretinal inflammation
0.665 0.335 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.665 0.335 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.664 0.335 0.000
S40-S49 Injuries to the shoulder and upper arm
0.664 0.336 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.664 0.336 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.664 0.336 0.000
H15 Disorders of sclera
0.664 0.336 0.000
S71 Open wound of hip and thigh
0.664 0.336 0.000
H34.8 Other retinal vascular occlusions
0.663 0.337 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
B91 Sequelae of poliomyelitis
0.661 0.339 0.000
F45 Somatoform disorders
0.661 0.339 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.661 0.339 0.000
G93.6 Cerebral oedema
0.661 0.339 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.661 0.339 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.660 0.340 0.000
O74 Complications of anaesthesia during labour and delivery
0.659 0.340 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.659 0.340 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.659 0.340 0.000
O60 Preterm delivery
0.659 0.340 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.659 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.659 0.341 0.000
Y35-Y36 Legal intervention and operations of war
0.659 0.341 0.000
Y10-Y34 Event of undetermined intent
0.659 0.341 0.000
X85-X99 Assault
0.659 0.341 0.000
X30-X39 Exposure to forces of nature
0.659 0.341 0.000
X10-X19 Contact with heat and hot substances
0.659 0.341 0.000
X00-X09 Exposure to smoke, fire and flames
0.659 0.341 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.659 0.341 0.000
W75-W84 Other accidental threats to breathing
0.659 0.341 0.000
W65-W74 Accidental drowning and submersion
0.659 0.341 0.000
V98-V99 Other and unspecified transport accidents
0.659 0.341 0.000
V95-V97 Air and space transport accidents
0.659 0.341 0.000
V90-V94 Water transport accidents
0.659 0.341 0.000
V70-V79 Bus occupant injured in transport accident
0.659 0.341 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.659 0.341 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.659 0.341 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.659 0.341 0.000
V01-V09 Pedestrian injured in transport accident
0.659 0.341 0.000
L81 Other disorders of pigmentation
0.659 0.341 0.000
H04.9 Disorder of lachrymal system, unspecified
0.659 0.341 0.000
H04.6 Other changes in lachrymal passages
0.659 0.341 0.000
H04.4 Chronic inflammation of lachrymal passages
0.659 0.341 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.659 0.341 0.000
H04.0 Dacryoadenitis
0.659 0.341 0.000
L93 Lupus erythematosus
0.657 0.342 0.000
G51 Facial nerve disorders
0.657 0.343 0.000
Q26 Congenital malformations of great veins
0.657 0.343 0.000
Q25 Congenital malformations of great arteries
0.657 0.343 0.000
Q24 Other congenital malformations of heart
0.657 0.343 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.657 0.343 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.657 0.343 0.000
F25 Schizoaffective disorders
0.657 0.343 0.000
F28 Other nonorganic psychotic disorders
0.656 0.344 0.000
F24 Induced delusional disorder
0.656 0.344 0.000
F21 Schizotypal disorder
0.656 0.344 0.000
A08 Viral and other specified intestinal infections
0.655 0.345 0.000
M05-M14 Inflammatory polyarthropathies
0.654 0.346 0.000
L10-L14 Bullous disorders
0.653 0.347 0.000
C34.3 Lower lobe, bronchus or lung
0.652 0.348 0.000
Q60-Q64 Congenital malformations of the urinary system
0.652 0.348 0.000
L03.1 Cellulitis of other parts of limb
0.652 0.348 0.000
I35 Nonrheumatic aortic valve disorders
0.652 0.348 0.000
F22.0 Delusional disorder
0.651 0.348 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.651 0.349 0.000
O66 Other obstructed labour
0.651 0.349 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.651 0.349 0.000
O62.1 Secondary uterine inertia
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.650 0.350 0.000
G82.2 Paraplegia, unspecified
0.650 0.350 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.650 0.350 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.650 0.350 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.650 0.350 0.000
T83.2 Mechanical complication of graft of urinary organ
0.650 0.350 0.000
F40 Phobic anxiety disorders
0.649 0.351 0.000
H04.2 Epiphora
0.649 0.351 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.648 0.352 0.000
G60 Hereditary and idiopathic neuropathy
0.648 0.352 0.000
C79.2 Secondary malignant neoplasm of skin
0.647 0.352 0.000
G95.9 Disease of spinal cord, unspecified
0.646 0.354 0.000
H02.3 Blepharochalasis
0.645 0.355 0.000
H20.0 Acute and subacute iridocyclitis
0.645 0.355 0.000
G30 Alzheimer's disease
0.644 0.356 0.000
I72 Other aneurysm
0.644 0.356 0.000
B35-B49 Mycoses
0.644 0.356 0.000
S99 Other and unspecified injuries of ankle and foot
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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