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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8042374
log Bayes Factor = 18.7395
Chromosome 15   position 78,908,032  (GRCh37) Explore rs8042374 on Ensembl!
Variant rs8042374 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.001 0.999
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.002 0.998
I73 Other peripheral vascular diseases
0.000 0.005 0.995
I70 Atherosclerosis
0.000 0.008 0.992
I73.9 Peripheral vascular disease, unspecified
0.000 0.011 0.989
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.014 0.986
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.019 0.981
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.026 0.974
J42 Unspecified chronic bronchitis
0.000 0.027 0.973
I77 Other disorders of arteries and arterioles
0.000 0.042 0.958
I72 Other aneurysm
0.000 0.099 0.901
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.101 0.899
I77.1 Stricture of artery
0.000 0.102 0.898
I73.0 Raynaud's syndrome
0.000 0.128 0.872
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.140 0.860
I74 Arterial embolism and thrombosis
0.000 0.166 0.834
J43.2 Centrilobular emphysema
0.000 0.190 0.810
I70.0 Atherosclerosis of aorta
0.000 0.200 0.800
I72.8 Aneurysm of other specified arteries
0.000 0.205 0.795
I77.0 Arteriovenous fistula, acquired
0.000 0.214 0.786
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.229 0.771
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.235 0.765
I72.0 Aneurysm of carotid artery
0.000 0.238 0.762
I77.2 Rupture of artery
0.000 0.241 0.759
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.246 0.754
I78 Diseases of capillaries
0.000 0.280 0.720
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.286 0.713
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I71.0 Dissection of aorta [any part]
0.000 0.291 0.709
I72.9 Aneurysm of unspecified site
0.000 0.297 0.703
I77.5 Necrosis of artery
0.000 0.313 0.687
I77.4 Coeliac artery compression syndrome
0.000 0.313 0.687
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.335 0.665
I74.5 Embolism and thrombosis of iliac artery
0.000 0.337 0.663
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.338 0.662
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.341 0.659
I72.3 Aneurysm of iliac artery
0.000 0.348 0.652
J40 Bronchitis, not specified as acute or chronic
0.000 0.351 0.649
J43.8 Other emphysema
0.000 0.352 0.648
I73.8 Other specified peripheral vascular diseases
0.000 0.352 0.648
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.354 0.646
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.354 0.646
I72.1 Aneurysm of artery of upper extremity
0.000 0.354 0.646
I60-I69 Cerebrovascular diseases
0.000 0.375 0.625
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.376 0.624
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.387 0.613
Chapter IX Diseases of the circulatory system
0.000 0.388 0.612
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.388 0.612
I60 Subarachnoid haemorrhage
0.000 0.388 0.612
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.393 0.607
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.402 0.598
I77.8 Other specified disorders of arteries and arterioles
0.000 0.402 0.598
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.404 0.596
I67 Other cerebrovascular diseases
0.000 0.404 0.596
I69 Sequelae of cerebrovascular disease
0.000 0.404 0.596
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.410 0.590
I72.4 Aneurysm of artery of lower extremity
0.000 0.411 0.589
I70.1 Atherosclerosis of renal artery
0.000 0.413 0.587
Chapter X Diseases of the respiratory system
0.000 0.416 0.584
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.420 0.580
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.426 0.573
I77.3 Arterial fibromuscular dysplasia
0.000 0.430 0.569
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.431 0.569
I67.9 Cerebrovascular disease, unspecified
0.000 0.435 0.565
I72.2 Aneurysm of renal artery
0.000 0.435 0.564
I69.3 Sequelae of cerebral infarction
0.000 0.437 0.563
J60-J70 Lung diseases due to external agents
0.000 0.441 0.559
J90-J94 Other diseases of pleura
0.000 0.447 0.553
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.447 0.553
I79.1 Aortitis in diseases classified elsewhere
0.000 0.447 0.553
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.447 0.553
J92 Pleural plaque
0.000 0.453 0.547
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.457 0.543
I26 Pulmonary embolism
0.000 0.464 0.536
J46 Status asthmaticus
0.000 0.466 0.534
I67.8 Other specified cerebrovascular diseases
0.000 0.467 0.533
I77.6 Arteritis, unspecified
0.000 0.467 0.533
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.470 0.530
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.472 0.528
I60.8 Other subarachnoid haemorrhage
0.000 0.473 0.527
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.476 0.524
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.477 0.523
J92.9 Pleural plaque without asbestos
0.000 0.481 0.519
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.483 0.517
I78.9 Disease of capillaries, unspecified
0.000 0.484 0.516
J92.0 Pleural plaque with presence of asbestos
0.000 0.485 0.515
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
J95-J99 Other diseases of the respiratory system
0.000 0.489 0.511
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I74.8 Embolism and thrombosis of other arteries
0.000 0.491 0.509
I27 Other pulmonary heart diseases
0.000 0.504 0.496
I78.8 Other diseases of capillaries
0.000 0.512 0.488
I67.1 Cerebral aneurysm, nonruptured
0.000 0.513 0.487
J86 Pyothorax
0.000 0.520 0.480
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.522 0.478
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.523 0.477
J90 Pleural effusion, not elsewhere classified
0.000 0.525 0.475
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.526 0.474
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.527 0.473
I27.9 Pulmonary heart disease, unspecified
0.000 0.530 0.470
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.532 0.468
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.542 0.458
J86.9 Pyothorax without fistula
0.000 0.542 0.458
J98 Other respiratory disorders
0.000 0.543 0.457
J60 Coalworker's pneumoconiosis
0.000 0.553 0.447
I78.1 Naevus, nonneoplastic
0.000 0.558 0.442
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.560 0.440
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.561 0.438
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.561 0.438
J69 Pneumonitis due to solids and liquids
0.000 0.563 0.437
I61 Intracerebral haemorrhage
0.000 0.565 0.435
I00-I02 Acute rheumatic fever
0.000 0.572 0.428
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.572 0.427
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.572 0.427
I67.5 Moyamoya disease
0.000 0.572 0.427
I67.4 Hypertensive encephalopathy
0.000 0.572 0.427
I67.3 Progressive vascular leukoencephalopathy
0.000 0.572 0.427
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.573 0.427
J64 Unspecified pneumoconiosis
0.000 0.577 0.423
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.579 0.421
J98.1 Pulmonary collapse
0.000 0.582 0.418
I28 Other diseases of pulmonary vessels
0.000 0.583 0.417
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.590 0.410
J98.4 Other disorders of lung
0.000 0.591 0.409
I27.8 Other specified pulmonary heart diseases
0.000 0.598 0.402
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.599 0.401
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.599 0.401
J66 Airway disease due to specific organic dust
0.000 0.599 0.401
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.599 0.401
J62 Pneumoconiosis due to dust containing silica
0.000 0.599 0.401
J65 Pneumoconiosis associated with tuberculosis
0.000 0.599 0.401
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.600 0.400
J98.9 Respiratory disorder, unspecified
0.000 0.607 0.393
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.608 0.392
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.610 0.390
J70 Respiratory conditions due to other external agents
0.000 0.616 0.384
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.617 0.382
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.625 0.375
I68.0 Cerebral amyloid angiopathy
0.000 0.629 0.371
J96 Respiratory failure, not elsewhere classified
0.000 0.634 0.366
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.639 0.361
I27.1 Kyphoscoliotic heart disease
0.000 0.644 0.356
J98.2 Interstitial emphysema
0.000 0.649 0.351
I62 Other nontraumatic intracranial haemorrhage
0.000 0.653 0.347
J69.8 Pneumonitis due to other solids and liquids
0.000 0.657 0.343
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.658 0.342
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.658 0.342
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.658 0.342
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.660 0.340
J93 Pneumothorax
0.000 0.662 0.338
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.670 0.330
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.672 0.328
J98.3 Compensatory emphysema
0.000 0.672 0.328
J85 Abscess of lung and mediastinum
0.000 0.673 0.327
J86.0 Pyothorax with fistula
0.000 0.675 0.325
J69.0 Pneumonitis due to food and vomit
0.000 0.678 0.322
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.681 0.319
J69.1 Pneumonitis due to oils and essences
0.000 0.687 0.313
I02 Rheumatic chorea
0.000 0.693 0.307
I01 Rheumatic fever with heart involvement
0.000 0.693 0.307
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.695 0.305
I28.8 Other specified diseases of pulmonary vessels
0.000 0.699 0.300
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.700 0.299
I28.1 Aneurysm of pulmonary artery
0.000 0.700 0.299
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.700 0.299
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.701 0.299
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.703 0.297
I00 Rheumatic fever without mention of heart involvement
0.000 0.705 0.295
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.705 0.294
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.706 0.294
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.706 0.294
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.706 0.294
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.706 0.294
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.708 0.292
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.708 0.292
J93.1 Other spontaneous pneumothorax
0.000 0.709 0.291
I05-I09 Chronic rheumatic heart diseases
0.000 0.710 0.290
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.711 0.289
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.712 0.287
J62.0 Pneumoconiosis due to talc dust
0.000 0.712 0.287
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.712 0.287
J63.5 Stannosis
0.000 0.712 0.287
J63.4 Siderosis
0.000 0.712 0.287
J63.3 Graphite fibrosis (of lung)
0.000 0.712 0.287
J63.2 Berylliosis
0.000 0.712 0.287
J63.1 Bauxite fibrosis (of lung)
0.000 0.712 0.287
J63.0 Aluminosis (of lung)
0.000 0.712 0.287
J66.8 Airway disease due to other specific organic dusts
0.000 0.712 0.287
J66.2 Cannabinosis
0.000 0.712 0.287
J66.1 Flax-dresser's disease
0.000 0.712 0.287
J66.0 Byssinosis
0.000 0.712 0.287
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.712 0.287
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.712 0.287
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.712 0.287
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.712 0.287
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.712 0.287
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.712 0.287
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.712 0.287
F17.1 Harmful use
0.000 0.713 0.287
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.713 0.287
J99.0 Rheumatoid lung disease
0.000 0.715 0.285
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.721 0.279
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.725 0.275
J70.8 Respiratory conditions due to other specified external agents
0.000 0.725 0.275
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.725 0.275
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.725 0.275
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.725 0.275
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.725 0.275
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.728 0.272
J95.8 Other postprocedural respiratory disorders
0.000 0.729 0.271
J98.8 Other specified respiratory disorders
0.000 0.731 0.269
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.732 0.268
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.732 0.268
J94 Other pleural conditions
0.000 0.733 0.266
J96.9 Respiratory failure, unspecified
0.000 0.737 0.263
J96.1 Chronic respiratory failure
0.000 0.737 0.263
J96.0 Acute respiratory failure
0.000 0.737 0.263
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.741 0.259
J67.7 Air-conditioner and humidifier lung
0.000 0.741 0.259
J67.6 Maple-bark-stripper's lung
0.000 0.741 0.259
J67.5 Mushroom-worker's lung
0.000 0.741 0.259
J67.4 Maltworker's lung
0.000 0.741 0.259
J67.3 Suberosis
0.000 0.741 0.259
J67.1 Bagassosis
0.000 0.741 0.259
J67.0 Farmer's lung
0.000 0.741 0.259
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.741 0.259
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.742 0.258
J98.6 Disorders of diaphragm
0.000 0.742 0.258
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.745 0.255
I61.8 Other intracerebral haemorrhage
0.000 0.749 0.251
J84 Other interstitial pulmonary diseases
0.000 0.750 0.250
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.750 0.249
J85.1 Abscess of lung with pneumonia
0.000 0.751 0.248
I27.0 Primary pulmonary hypertension
0.000 0.755 0.244
J95.5 Postprocedural subglottic stenosis
0.000 0.756 0.244
J95.4 Mendelson's syndrome
0.000 0.756 0.244
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.756 0.244
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.756 0.244
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.756 0.244
J85.3 Abscess of mediastinum
0.000 0.765 0.234
J85.0 Gangrene and necrosis of lung
0.000 0.765 0.234
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.766 0.234
J67.2 Bird fancier's lung
0.000 0.768 0.232
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.768 0.231
I09 Other rheumatic heart diseases
0.000 0.769 0.231
J93.0 Spontaneous tension pneumothorax
0.000 0.771 0.229
J95.0 Tracheostomy malfunction
0.000 0.771 0.228
J45 Asthma
0.000 0.772 0.228
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.774 0.226
I67.2 Cerebral atherosclerosis
0.000 0.774 0.226
I27.2 Other secondary pulmonary hypertension
0.000 0.775 0.225
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.780 0.220
I01.8 Other acute rheumatic heart disease
0.000 0.780 0.220
I01.2 Acute rheumatic myocarditis
0.000 0.780 0.220
I01.1 Acute rheumatic endocarditis
0.000 0.780 0.220
I01.0 Acute rheumatic pericarditis
0.000 0.780 0.220
I02.9 Rheumatic chorea without heart involvement
0.000 0.780 0.220
I02.0 Rheumatic chorea with heart involvement
0.000 0.780 0.220
J91 Pleural effusion in conditions classified elsewhere
0.000 0.780 0.220
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.782 0.218
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.783 0.217
J09-J18 Influenza and pneumonia
0.000 0.792 0.208
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.793 0.207
I06 Rheumatic aortic valve diseases
0.000 0.794 0.206
I05 Rheumatic mitral valve diseases
0.000 0.795 0.205
J93.8 Other pneumothorax
0.000 0.796 0.204
I62.1 Nontraumatic extradural haemorrhage
0.000 0.796 0.204
J84.8 Other specified interstitial pulmonary diseases
0.000 0.798 0.202
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.799 0.201
I07 Rheumatic tricuspid valve diseases
0.000 0.801 0.199
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.806 0.194
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.807 0.193
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.807 0.192
J94.9 Pleural condition, unspecified
0.000 0.809 0.191
J94.0 Chylous effusion
0.000 0.809 0.191
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.809 0.191
J96.09 Acute respiratory failure; Type unspecified
0.000 0.811 0.188
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.811 0.188
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.811 0.188
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.811 0.188
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.811 0.188
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.811 0.188
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.811 0.188
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.811 0.188
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.811 0.188
I09.9 Rheumatic heart disease, unspecified
0.000 0.811 0.189
J20-J22 Other acute lower respiratory infections
0.000 0.813 0.187
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.815 0.185
I99 Other and unspecified disorders of circulatory system
0.000 0.816 0.184
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.817 0.183
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.817 0.183
I98.0 Cardiovascular syphilis
0.000 0.817 0.183
J84.0 Alveolar and parietoalveolar conditions
0.000 0.821 0.179
I05.1 Rheumatic mitral insufficiency
0.000 0.827 0.173
J94.8 Other specified pleural conditions
0.000 0.827 0.173
F17.2 Dependence syndrome
0.000 0.827 0.173
J94.1 Fibrothorax
0.000 0.828 0.172
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.832 0.168
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.832 0.168
J85.2 Abscess of lung without pneumonia
0.001 0.833 0.166
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.833 0.166
I09.8 Other specified rheumatic heart diseases
0.000 0.834 0.166
I09.2 Chronic rheumatic pericarditis
0.000 0.834 0.166
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.834 0.166
I09.0 Rheumatic myocarditis
0.000 0.834 0.166
J45.8 Mixed asthma
0.000 0.836 0.164
J45.1 Nonallergic asthma
0.000 0.836 0.164
J00-J06 Acute upper respiratory infections
0.000 0.837 0.163
I05.0 Mitral stenosis
0.000 0.843 0.157
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.844 0.155
I97.0 Postcardiotomy syndrome
0.000 0.844 0.155
J18 Pneumonia, organism unspecified
0.000 0.845 0.155
J10 Influenza due to identified influenza virus
0.000 0.845 0.155
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.846 0.154
J18.1 Lobar pneumonia, unspecified
0.000 0.850 0.150
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.851 0.149
J09 Influenza due to certain identified influenza virus
0.000 0.851 0.149
J17 Pneumonia in diseases classified elsewhere
0.000 0.851 0.149
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.852 0.148
I06.8 Other rheumatic aortic valve diseases
0.000 0.852 0.148
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.852 0.148
I06.1 Rheumatic aortic insufficiency
0.000 0.852 0.148
I05.8 Other mitral valve diseases
0.000 0.852 0.147
I06.0 Rheumatic aortic stenosis
0.000 0.854 0.145
J93.9 Pneumothorax, unspecified
0.000 0.856 0.144
I95 Hypotension
0.000 0.856 0.143
I07.9 Tricuspid valve disease, unspecified
0.000 0.857 0.143
I07.8 Other tricuspid valve diseases
0.000 0.857 0.143
I07.2 Tricuspid stenosis with insufficiency
0.000 0.857 0.143
I07.0 Tricuspid stenosis
0.000 0.857 0.143
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.858 0.142
F17.9 Unspecified mental and behavioural disorder
0.000 0.863 0.137
F17.8 Other mental and behavioural disorders
0.000 0.863 0.137
F17.7 Residual and late-onset psychotic disorder
0.000 0.863 0.137
F17.6 Amnesic syndrome
0.000 0.863 0.137
F17.5 Psychotic disorder
0.000 0.863 0.137
F17.4 Withdrawal state with delirium
0.000 0.863 0.137
F17.3 Withdrawal state
0.000 0.863 0.137
J12 Viral pneumonia, not elsewhere classified
0.000 0.865 0.135
J94.2 Haemothorax
0.000 0.865 0.135
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.865 0.134
I07.1 Tricuspid insufficiency
0.000 0.866 0.134
F17.0 Acute intoxication
0.000 0.870 0.130
I97.1 Other functional disturbances following cardiac surgery
0.000 0.870 0.129
J00 Acute nasopharyngitis [common cold]
0.000 0.871 0.129
I95.1 Orthostatic hypotension
0.000 0.873 0.127
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.874 0.126
I65.1 Occlusion and stenosis of basilar artery
0.000 0.876 0.124
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.876 0.124
I05.2 Mitral stenosis with insufficiency
0.000 0.878 0.122
J21 Acute bronchiolitis
0.000 0.880 0.120
J14 Pneumonia due to Haemophilus influenzae
0.000 0.882 0.118
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.882 0.118
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.882 0.118
I05.9 Mitral valve disease, unspecified
0.000 0.883 0.117
I63 Cerebral infarction
0.000 0.883 0.117
J20 Acute bronchitis
0.000 0.884 0.116
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.884 0.116
I95.8 Other hypotension
0.000 0.886 0.114
J18.2 Hypostatic pneumonia, unspecified
0.000 0.888 0.112
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.889 0.111
J82 Pulmonary eosinophilia, not elsewhere classified
0.001 0.891 0.109
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.891 0.109
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.893 0.107
J16.0 Chlamydial pneumonia
0.000 0.893 0.107
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.893 0.107
J18.8 Other pneumonia, organism unspecified
0.000 0.896 0.104
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.900 0.100
I65.2 Occlusion and stenosis of carotid artery
0.000 0.901 0.099
J11 Influenza, virus not identified
0.000 0.902 0.098
J15.2 Pneumonia due to staphylococcus
0.000 0.902 0.098
J12.8 Other viral pneumonia
0.000 0.903 0.097
J12.3 Human metapneumovirus pneumonia
0.000 0.903 0.097
J12.2 Parainfluenza virus pneumonia
0.000 0.903 0.097
J12.1 Respiratory syncytial virus pneumonia
0.000 0.903 0.097
J12.0 Adenoviral pneumonia
0.000 0.903 0.097
J04 Acute laryngitis and tracheitis
0.000 0.903 0.097
J15.5 Pneumonia due to Escherichia coli
0.000 0.904 0.096
J05.1 Acute epiglottitis
0.000 0.904 0.096
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.904 0.096
J01 Acute sinusitis
0.000 0.904 0.096
J15.8 Other bacterial pneumonia
0.000 0.906 0.094
J17.3 Pneumonia in parasitic diseases
0.000 0.907 0.092
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.908 0.092
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.909 0.091
J81 Pulmonary oedema
0.000 0.910 0.090
J15.3 Pneumonia due to streptococcus, group B
0.000 0.910 0.090
J02 Acute pharyngitis
0.000 0.910 0.090
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.911 0.089
J05.0 Acute obstructive laryngitis [croup]
0.000 0.911 0.089
J15.9 Bacterial pneumonia, unspecified
0.000 0.913 0.087
J03 Acute tonsillitis
0.000 0.913 0.087
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.913 0.086
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.913 0.086
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.913 0.086
J15.4 Pneumonia due to other streptococci
0.000 0.914 0.086
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.916 0.084
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.916 0.084
J20.7 Acute bronchitis due to echovirus
0.000 0.916 0.083
J20.6 Acute bronchitis due to rhinovirus
0.000 0.916 0.083
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.916 0.083
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.916 0.083
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.916 0.083
J20.2 Acute bronchitis due to streptococcus
0.000 0.916 0.083
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.916 0.083
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.916 0.083
J12.9 Viral pneumonia, unspecified
0.000 0.917 0.083
J20.8 Acute bronchitis due to other specified organisms
0.000 0.919 0.081
J17.2 Pneumonia in mycoses
0.000 0.919 0.080
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.920 0.080
I95.0 Idiopathic hypotension
0.000 0.920 0.079
J47 Bronchiectasis
0.000 0.920 0.080
J80 Adult respiratory distress syndrome
0.001 0.922 0.077
I10-I15 Hypertensive diseases
0.000 0.924 0.076
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.925 0.075
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.927 0.073
J21.9 Acute bronchiolitis, unspecified
0.000 0.927 0.072
J04.1 Acute tracheitis
0.000 0.928 0.072
J18.9 Pneumonia, unspecified
0.000 0.928 0.072
J45.0 Predominantly allergic asthma
0.000 0.929 0.071
J11.8 Influenza with other manifestations, virus not identified
0.000 0.929 0.070
J04.2 Acute laryngotracheitis
0.000 0.930 0.069
J01.8 Other acute sinusitis
0.000 0.931 0.069
J01.4 Acute pansinusitis
0.000 0.931 0.069
J01.3 Acute sphenoidal sinusitis
0.000 0.931 0.069
J01.1 Acute frontal sinusitis
0.000 0.931 0.069
J20.9 Acute bronchitis, unspecified
0.000 0.931 0.069
J01.0 Acute maxillary sinusitis
0.000 0.932 0.068
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.935 0.065
J15.1 Pneumonia due to Pseudomonas
0.000 0.936 0.064
J02.0 Streptococcal pharyngitis
0.000 0.937 0.062
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.937 0.062
J03.0 Streptococcal tonsillitis
0.000 0.937 0.062
J01.9 Acute sinusitis, unspecified
0.000 0.940 0.060
J01.2 Acute ethmoidal sinusitis
0.000 0.940 0.060
J11.0 Influenza with pneumonia, virus not identified
0.000 0.940 0.060
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.940 0.060
I13 Hypertensive heart and renal disease
0.000 0.945 0.054
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.946 0.054
J06.0 Acute laryngopharyngitis
0.000 0.946 0.054
N64 Other disorders of breast
0.052 0.948 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.949 0.051
N64.5 Other signs and symptoms in breast
0.050 0.950 0.000
N64.8 Other specified disorders of breast
0.048 0.952 0.000
I15 Secondary hypertension
0.000 0.953 0.047
N64.1 Fat necrosis of breast
0.047 0.953 0.000
N64.9 Disorder of breast, unspecified
0.046 0.954 0.000
J04.0 Acute laryngitis
0.000 0.955 0.045
N64.4 Mastodynia
0.045 0.955 0.000
I95.9 Hypotension, unspecified
0.000 0.957 0.043
J02.9 Acute pharyngitis, unspecified
0.000 0.958 0.042
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.959 0.041
N64.3 Galactorrhoea not associated with childbirth
0.040 0.960 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.961 0.039
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.961 0.039
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.961 0.039
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.961 0.039
I11 Hypertensive heart disease
0.000 0.961 0.039
Z50.1 Other physical therapy
0.000 0.962 0.038
I63.8 Other cerebral infarction
0.000 0.962 0.038
N64.2 Atrophy of breast
0.037 0.963 0.000
N64.0 Fissure and fistula of nipple
0.037 0.963 0.000
J18.0 Bronchopneumonia, unspecified
0.000 0.963 0.037
I95.2 Hypotension due to drugs
0.000 0.964 0.036
Z50 Care involving use of rehabilitation procedures
0.000 0.965 0.035
I15.9 Seconday hypertension, unspecified
0.000 0.965 0.034
I15.8 Other secondary hypertension
0.000 0.966 0.034
I15.2 Hypertension secondary to endocrine disorders
0.000 0.966 0.034
I15.1 Hypertension secondary to other renal disorders
0.000 0.966 0.034
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.967 0.033
Z50.5 Speech therapy
0.000 0.968 0.032
J03.9 Acute tonsillitis, unspecified
0.000 0.968 0.032
Z50.2 Alcohol rehabilitation
0.000 0.969 0.031
C67 Malignant neoplasm of bladder
0.000 0.971 0.029
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.971 0.029
C67.6 Ureteric orifice
0.000 0.971 0.029
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.972 0.028
C67.2 Lateral wall of bladder
0.000 0.972 0.028
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.972 0.027
I15.0 Renovascular hypertension
0.000 0.973 0.027

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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