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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8044050
log Bayes Factor = 16.7322
Chromosome 16   position 74,922,857  (GRCh37) Explore rs8044050 on Ensembl!
Variant rs8044050 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
F41 Other anxiety disorders
0.983 0.017 0.000
E70-E90 Metabolic disorders
0.976 0.024 0.000
F41.9 Anxiety disorder, unspecified
0.975 0.025 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.975 0.025 0.000
I21 Acute myocardial infarction
0.975 0.025 0.000
W00-W19 Falls
0.974 0.026 0.000
M50-M54 Other dorsopathies
0.974 0.026 0.000
M54 Dorsalgia
0.970 0.030 0.000
I22 Subsequent myocardial infarction
0.968 0.032 0.000
E10-E14 Diabetes mellitus
0.968 0.032 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.965 0.035 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.963 0.037 0.000
I05-I09 Chronic rheumatic heart diseases
0.961 0.039 0.000
I25 Chronic ischaemic heart disease
0.958 0.042 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.954 0.046 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.951 0.049 0.000
G90-G99 Other disorders of the nervous system
0.943 0.057 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.943 0.057 0.000
E11 Non-insulin-dependent diabetes mellitus
0.942 0.058 0.000
I25.2 Old myocardial infarction
0.941 0.059 0.000
S00-S09 Injuries to the head
0.941 0.059 0.000
I73 Other peripheral vascular diseases
0.940 0.060 0.000
I50 Heart failure
0.935 0.065 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.935 0.065 0.000
M54.5 Low back pain
0.934 0.066 0.000
G56 Mononeuropathies of upper limb
0.931 0.069 0.000
E87.5 Hyperkalaemia
0.926 0.074 0.000
G56.0 Carpal tunnel syndrome
0.920 0.080 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.913 0.087 0.000
I73.9 Peripheral vascular disease, unspecified
0.912 0.088 0.000
I45 Other conduction disorders
0.911 0.089 0.000
S01 Open wound of head
0.909 0.091 0.000
G20-G26 Extrapyramidal and movement disorders
0.909 0.091 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.907 0.093 0.000
I26 Pulmonary embolism
0.907 0.093 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.900 0.100 0.000
I50.9 Heart failure, unspecified
0.896 0.104 0.000
S90-S99 Injuries to the ankle and foot
0.896 0.104 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.895 0.105 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.895 0.105 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.893 0.107 0.000
E86 Volume depletion
0.893 0.107 0.000
M05-M14 Inflammatory polyarthropathies
0.891 0.109 0.000
M54.9 Dorsalgia, unspecified
0.890 0.110 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.889 0.111 0.000
M54.3 Sciatica
0.886 0.114 0.000
M54.57 Low back pain (Lumbosacral region)
0.884 0.116 0.000
I51 Complications and ill-defined descriptions of heart disease
0.881 0.119 0.000
Chapter VIII Diseases of the ear and mastoid process
0.881 0.119 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.873 0.127 0.000
Y45.0 Opioids and related analgesics
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.872 0.128 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.869 0.131 0.000
Chapter I Certain infectious and parasitic diseases
0.868 0.132 0.000
I08 Multiple valve diseases
0.864 0.136 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.863 0.137 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.861 0.139 0.000
M70-M79 Other soft tissue disorders
0.860 0.140 0.000
E14 Unspecified diabetes mellitus
0.859 0.141 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.859 0.141 0.000
G30-G32 Other degenerative diseases of the nervous system
0.857 0.143 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.856 0.143 0.000
F03 Unspecified dementia
0.856 0.144 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.847 0.153 0.000
W13 Fall from, out of or through building or structure
0.845 0.155 0.000
W19 Unspecified fall
0.839 0.161 0.000
M86-M90 Other osteopathies
0.838 0.162 0.000
I10-I15 Hypertensive diseases
0.837 0.163 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.836 0.164 0.000
G20 Parkinson's disease
0.835 0.165 0.000
I07 Rheumatic tricuspid valve diseases
0.831 0.169 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.830 0.170 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.829 0.171 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.829 0.171 0.000
Y40 Systemic antibiotics
0.828 0.172 0.000
E20-E35 Disorders of other endocrine glands
0.828 0.172 0.000
M54.39 Sciatica (Site unspecified)
0.828 0.172 0.000
I71 Aortic aneurysm and dissection
0.827 0.173 0.000
E11.9 Without complications
0.827 0.173 0.000
H90-H95 Other disorders of ear
0.824 0.176 0.000
E11.3 With ophthalmic complications
0.822 0.178 0.000
Y48 Anaesthetics and therapeutic gases
0.820 0.180 0.000
R47-R49 Symptoms and signs involving speech and voice
0.819 0.181 0.000
E65-E68 Obesity and other hyperalimentation
0.817 0.183 0.000
G91 Hydrocephalus
0.813 0.187 0.000
Y42.7 Androgens and anabolic congeners
0.812 0.188 0.000
M54.59 Low back pain (Site unspecified)
0.810 0.190 0.000
Y43 Primarily systemic agents
0.809 0.191 0.000
G51 Facial nerve disorders
0.808 0.192 0.000
T81 Complications of procedures, not elsewhere classified
0.808 0.192 0.000
R50-R69 General symptoms and signs
0.807 0.193 0.000
I51.7 Cardiomegaly
0.805 0.195 0.000
G95 Other diseases of spinal cord
0.804 0.196 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.804 0.196 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.804 0.196 0.000
A30-A49 Other bacterial diseases
0.803 0.197 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.800 0.200 0.000
M06 Other rheumatoid arthritis
0.799 0.201 0.000
I05 Rheumatic mitral valve diseases
0.798 0.202 0.000
S01.9 Open wound of head, part unspecified
0.795 0.205 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.792 0.208 0.000
T79-T79 Certain early complications of trauma
0.789 0.210 0.000
M40-M43 Deforming dorsopathies
0.788 0.212 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.788 0.212 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.787 0.213 0.000
E87.0 Hyperosmolality and hypernatraemia
0.787 0.213 0.000
R26 Abnormalities of gait and mobility
0.786 0.214 0.000
I12 Hypertensive renal disease
0.786 0.214 0.000
Chapter XXII Codes for special purposes
0.785 0.214 0.000
W17 Other fall from one level to another
0.783 0.216 0.000
E11.6 With other specified complications
0.782 0.218 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.782 0.218 0.000
E14.9 Without complications
0.781 0.219 0.000
R59 Enlarged lymph nodes
0.781 0.219 0.000
I60-I69 Cerebrovascular diseases
0.780 0.220 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.778 0.222 0.000
W18 Other fall on same level
0.778 0.222 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.778 0.222 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.777 0.222 0.000
Y44 Agents primarily affecting blood constituents
0.777 0.223 0.000
E88 Other metabolic disorders
0.777 0.223 0.000
M15-M19 Arthrosis
0.776 0.224 0.000
S01.4 Open wound of cheek and temporomandibular area
0.775 0.225 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.774 0.226 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.773 0.227 0.000
G40-G47 Episodic and paroxysmal disorders
0.771 0.229 0.000
S92 Fracture of foot, except ankle
0.770 0.230 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.770 0.230 0.000
I72 Other aneurysm
0.768 0.232 0.000
R25 Abnormal involuntary movements
0.768 0.232 0.000
I27 Other pulmonary heart diseases
0.768 0.232 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.768 0.232 0.000
S50-S59 Injuries to the elbow and forearm
0.764 0.235 0.000
E11.1 With ketoacidosis
0.764 0.236 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.764 0.236 0.000
L03 Cellulitis
0.764 0.236 0.000
Y57 Other and unspecified drugs and medicaments
0.764 0.236 0.000
I42 Cardiomyopathy
0.762 0.238 0.000
F41.2 Mixed anxiety and depressive disorder
0.762 0.238 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.761 0.239 0.000
V10-V19 Pedal cyclist injured in transport accident
0.761 0.239 0.000
R53 Malaise and fatigue
0.759 0.241 0.000
R59.0 Localised enlarged lymph nodes
0.759 0.241 0.000
V40-V49 Car occupant injured in transport accident
0.758 0.242 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.756 0.244 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.755 0.245 0.000
I49 Other cardiac arrhythmias
0.754 0.246 0.000
I46 Cardiac arrest
0.754 0.246 0.000
Y52 Agents primarily affecting the cardiovascular system
0.753 0.247 0.000
W13.9 Unspecified place
0.752 0.248 0.000
I74 Arterial embolism and thrombosis
0.752 0.248 0.000
S00 Superficial injury of head
0.752 0.248 0.000
I25.5 Ischaemic cardiomyopathy
0.751 0.249 0.000
F25 Schizoaffective disorders
0.750 0.250 0.000
I51.4 Myocarditis, unspecified
0.750 0.250 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.750 0.250 0.000
O36 Maternal care for other known or suspected foetal problems
0.750 0.250 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.749 0.251 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
I45.8 Other specified conduction disorders
0.748 0.252 0.000
M19 Other arthrosis
0.746 0.253 0.000
F60-F69 Disorders of adult personality and behaviour
0.746 0.254 0.000
F20 Schizophrenia
0.746 0.254 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.746 0.254 0.000
I36 Nonrheumatic tricuspid valve disorders
0.745 0.255 0.000
V20-V29 Motorcycle rider injured in transport accident
0.744 0.256 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.744 0.256 0.000
F43 Reaction to severe stress, and adjustment disorders
0.742 0.257 0.000
I45.9 Conduction disorder, unspecified
0.738 0.262 0.000
I07.1 Tricuspid insufficiency
0.737 0.263 0.000
F42 Obsessive-compulsive disorder
0.737 0.263 0.000
G62 Other polyneuropathies
0.737 0.263 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.737 0.263 0.000
S01.1 Open wound of eyelid and periocular area
0.736 0.264 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.735 0.265 0.000
G58 Other mononeuropathies
0.735 0.265 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.735 0.265 0.000
R47 Speech disturbances, not elsewhere classified
0.734 0.266 0.000
I25.3 Aneurysm of heart
0.734 0.266 0.000
W06 Fall involving bed
0.734 0.266 0.000
X60-X84 Intentional self-harm
0.734 0.266 0.000
G70-G73 Diseases of myoneural junction and muscle
0.733 0.267 0.000
W08 Fall involving other furniture
0.733 0.267 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.732 0.268 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.732 0.268 0.000
I45.5 Other specified heart block
0.732 0.268 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.731 0.269 0.000
L82 Seborrhoeic keratosis
0.731 0.269 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.269 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.730 0.269 0.000
E11.4 With neurological complications
0.730 0.270 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.729 0.271 0.000
I44 Atrioventricular and left bundle-branch block
0.729 0.271 0.000
I45.2 Bifascicular block
0.727 0.273 0.000
G90 Disorders of autonomic nervous system
0.726 0.274 0.000
F80-F89 Disorders of psychological development
0.726 0.274 0.000
F29 Unspecified nonorganic psychosis
0.725 0.275 0.000
I38 Endocarditis, valve unspecified
0.725 0.275 0.000
I35 Nonrheumatic aortic valve disorders
0.724 0.275 0.000
M45-M49 Spondylopathies
0.724 0.276 0.000
G30 Alzheimer's disease
0.724 0.276 0.000
I50.0 Congestive heart failure
0.723 0.277 0.000
R25.1 Tremor, unspecified
0.723 0.277 0.000
M06.9 Rheumatoid arthritis, unspecified
0.722 0.278 0.000
M54.6 Pain in thoracic spine
0.722 0.278 0.000
L20-L30 Dermatitis and eczema
0.721 0.278 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.719 0.281 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.719 0.281 0.000
M54.4 Lumbago with sciatica
0.719 0.281 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.719 0.281 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.718 0.282 0.000
S01.3 Open wound of ear
0.718 0.282 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I45.3 Trifascicular block
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
W19.9 Unspecified place
0.715 0.285 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.714 0.285 0.000
Y59 Other and unspecified vaccines and biological substances
0.714 0.286 0.000
Y58 Bacterial vaccines
0.714 0.286 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.714 0.286 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.714 0.286 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.714 0.286 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.714 0.286 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.714 0.286 0.000
G24 Dystonia
0.714 0.286 0.000
W20-W49 Exposure to inanimate mechanical forces
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
S05 Injury of eye and orbit
0.712 0.288 0.000
T85.2 Mechanical complication of intraocular lens
0.712 0.288 0.000
I73.0 Raynaud's syndrome
0.712 0.288 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.710 0.290 0.000
S06 Intracranial injury
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.710 0.290 0.000
G91.1 Obstructive hydrocephalus
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
A41 Other septicaemia
0.709 0.291 0.000
F00 Dementia in Alzheimer's disease
0.709 0.291 0.000
F48 Other neurotic disorders
0.709 0.291 0.000
F44 Dissociative [conversion] disorders
0.709 0.291 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
H91 Other hearing loss
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
Y40.0 Penicillins
0.707 0.293 0.000
G03 Meningitis due to other and unspecified causes
0.707 0.293 0.000
M54.1 Radiculopathy
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.706 0.294 0.000
T86 Failure and rejection of transplanted organs and tissues
0.706 0.294 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.706 0.294 0.000
M86 Osteomyelitis
0.706 0.294 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.706 0.294 0.000
F41.8 Other specified anxiety disorders
0.705 0.295 0.000
F41.3 Other mixed anxiety disorders
0.705 0.295 0.000
F41.1 Generalised anxiety disorder
0.705 0.295 0.000
W07 Fall involving chair
0.705 0.295 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.704 0.296 0.000
I80 Phlebitis and thrombophlebitis
0.704 0.296 0.000
I70 Atherosclerosis
0.702 0.297 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.702 0.298 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.702 0.298 0.000
M91-M94 Chondropathies
0.700 0.299 0.000
S01.0 Open wound of scalp
0.700 0.300 0.000
E85 Amyloidosis
0.700 0.300 0.000
E84 Cystic fibrosis
0.700 0.300 0.000
E79 Disorders of purine and pyrimidine metabolism
0.700 0.300 0.000
E77 Disorders of glycoprotein metabolism
0.700 0.300 0.000
E76 Disorders of glycosaminoglycan metabolism
0.700 0.300 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.700 0.300 0.000
E74 Other disorders of carbohydrate metabolism
0.700 0.300 0.000
E73 Lactose intolerance
0.700 0.300 0.000
E72 Other disorders of amino-acid metabolism
0.700 0.300 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.700 0.300 0.000
E70 Disorders of aromatic amino-acid metabolism
0.700 0.300 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.700 0.300 0.000
M19.9 Arthrosis, unspecified
0.700 0.300 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.699 0.301 0.000
I12.0 Hypertensive renal disease with renal failure
0.699 0.301 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.699 0.301 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.699 0.301 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.699 0.301 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.698 0.302 0.000
W15 Fall from cliff
0.698 0.302 0.000
W14 Fall from tree
0.698 0.302 0.000
W12 Fall on and from scaffolding
0.698 0.302 0.000
W11 Fall on and from ladder
0.698 0.302 0.000
W09 Fall involving playground equipment
0.698 0.302 0.000
W05 Fall involving wheelchair
0.698 0.302 0.000
W04 Fall while being carried or supported by other persons
0.698 0.302 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.698 0.302 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.698 0.302 0.000
W00 Fall on same level involving ice and snow
0.698 0.302 0.000
E40-E46 Malnutrition
0.698 0.302 0.000
F45 Somatoform disorders
0.697 0.302 0.000
M54.50 Low back pain (Multiple sites in spine)
0.697 0.303 0.000
E50-E64 Other nutritional deficiencies
0.697 0.303 0.000
G93 Other disorders of brain
0.696 0.304 0.000
M54.8 Other dorsalgia
0.696 0.304 0.000
M54.0 Panniculitis affecting regions of neck and back
0.696 0.304 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.696 0.304 0.000
L03.2 Cellulitis of face
0.695 0.305 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.694 0.305 0.000
I22.8 Subsequent myocardial infarction of other sites
0.694 0.306 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.694 0.306 0.000
E12 Malnutrition-related diabetes mellitus
0.694 0.306 0.000
Y48.3 Local anaesthetics
0.693 0.307 0.000
A49 Bacterial infection of unspecified site
0.692 0.308 0.000
I12.9 Hypertensive renal disease without renal failure
0.692 0.308 0.000
S01.5 Open wound of lip and oral cavity
0.691 0.308 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.690 0.309 0.000
G52 Disorders of other cranial nerves
0.690 0.309 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.690 0.309 0.000
I09 Other rheumatic heart diseases
0.689 0.311 0.000
I06 Rheumatic aortic valve diseases
0.689 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.689 0.311 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.688 0.312 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.688 0.312 0.000
E66 Obesity
0.687 0.313 0.000
I25.6 Silent myocardial ischaemia
0.687 0.313 0.000
I25.4 Coronary artery aneurysm
0.687 0.313 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.687 0.313 0.000
S99 Other and unspecified injuries of ankle and foot
0.686 0.314 0.000
I45.1 Other and unspecified right bundle-branch block
0.686 0.314 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.685 0.314 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.685 0.315 0.000
I28 Other diseases of pulmonary vessels
0.684 0.316 0.000
M13 Other arthritis
0.684 0.316 0.000
M53 Other dorsopathies, not elsewhere classified
0.683 0.317 0.000
M80-M85 Disorders of bone density and structure
0.683 0.317 0.000
M79.6 Pain in limb
0.683 0.317 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.682 0.318 0.000
Y45.8 Other analgesics and antipyretics
0.682 0.318 0.000
Y45.5 4-Aminophenol derivatives
0.682 0.318 0.000
Y45.4 Antirheumatics
0.682 0.318 0.000
Y45.2 Propionic acid derivatives
0.682 0.318 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.682 0.318 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.682 0.318 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.681 0.319 0.000
R45 Symptoms and signs involving emotional state
0.680 0.319 0.000
H90 Conductive and sensorineural hearing loss
0.680 0.319 0.000
R27 Other lack of coordination
0.680 0.320 0.000
G54 Nerve root and plexus disorders
0.679 0.321 0.000
S20-S29 Injuries to the thorax
0.678 0.321 0.000
M10 Gout
0.678 0.322 0.000
E13 Other specified diabetes mellitus
0.678 0.322 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.676 0.324 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.676 0.324 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.676 0.324 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.676 0.324 0.000
G92 Toxic encephalopathy
0.676 0.324 0.000
E87.4 Mixed disorder of acid-base balance
0.676 0.324 0.000
E87.3 Alkalosis
0.676 0.324 0.000
O85-O92 Complications predominantly related to the puerperium
0.675 0.325 0.000
E11.8 With unspecified complications
0.675 0.325 0.000
E11.7 With multiple complications
0.675 0.325 0.000
E11.0 With coma
0.675 0.325 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.325 0.000
S08 Traumatic amputation of part of head
0.675 0.325 0.000
S07 Crushing injury of head
0.675 0.325 0.000
S04 Injury of cranial nerves
0.675 0.325 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.675 0.325 0.000
I73.8 Other specified peripheral vascular diseases
0.674 0.326 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.674 0.326 0.000
S92.3 Fracture of metatarsal bone
0.674 0.326 0.000
F40 Phobic anxiety disorders
0.673 0.327 0.000
W19.1 Residential institution
0.672 0.328 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.672 0.328 0.000
G95.2 Cord compression, unspecified
0.672 0.328 0.000
R49 Voice disturbances
0.672 0.328 0.000
Y42.5 Other oestrogens and progestogens
0.672 0.328 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.671 0.328 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.671 0.329 0.000
E11.5 With peripheral circulatory complications
0.671 0.329 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.670 0.330 0.000
F02 Dementia in other diseases classified elsewhere
0.670 0.330 0.000
F09 Unspecified organic or symptomatic mental disorder
0.670 0.330 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.670 0.330 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.670 0.330 0.000
O60-O75 Complications of labour and delivery
0.670 0.330 0.000
M54.55 Low back pain (Thoracolumbar region)
0.670 0.330 0.000
M54.54 Low back pain-Thoracic
0.670 0.330 0.000
M54.53 Low back pain-Cervicothoracic
0.670 0.330 0.000
M54.52 Low back pain-Cervical
0.670 0.330 0.000
M54.51 Low back pain-Occipit-atl-axl
0.670 0.330 0.000
I69 Sequelae of cerebrovascular disease
0.670 0.330 0.000
E20 Hypoparathyroidism
0.669 0.331 0.000
Q60-Q64 Congenital malformations of the urinary system
0.669 0.331 0.000
E87.7 Fluid overload
0.669 0.331 0.000
G44 Other headache syndromes
0.669 0.331 0.000
S60-S69 Injuries to the wrist and hand
0.668 0.332 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.667 0.332 0.000
G56.8 Other mononeuropathies of upper limb
0.667 0.332 0.000
G56.4 Causalgia
0.667 0.332 0.000
G56.3 Lesion of radial nerve
0.667 0.332 0.000
G56.1 Other lesions of median nerve
0.667 0.332 0.000
L03.3 Cellulitis of trunk
0.667 0.333 0.000
W10 Fall on and from stairs and steps
0.666 0.333 0.000
G96 Other disorders of central nervous system
0.666 0.333 0.000
S40-S49 Injuries to the shoulder and upper arm
0.666 0.334 0.000
I60 Subarachnoid haemorrhage
0.666 0.334 0.000
M54.2 Cervicalgia
0.666 0.334 0.000
I21.4 Acute subendocardial myocardial infarction
0.666 0.334 0.000
R59.9 Enlarged lymph nodes, unspecified
0.665 0.335 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.665 0.335 0.000
I49.5 Sick sinus syndrome
0.664 0.336 0.000
G61 Inflammatory polyneuropathy
0.661 0.338 0.000
M19.0 Primary arthrosis of other joints
0.661 0.339 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.660 0.340 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.660 0.340 0.000
Y43.3 Other antineoplastic drugs
0.658 0.342 0.000
L81 Other disorders of pigmentation
0.658 0.342 0.000
M07 Psoriatic and enteropathic arthropathies
0.657 0.343 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.657 0.343 0.000
I24 Other acute ischaemic heart diseases
0.657 0.343 0.000
Y45.1 Salicylates
0.657 0.343 0.000
S80-S89 Injuries to the knee and lower leg
0.657 0.343 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.656 0.344 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.656 0.344 0.000
R60 Oedema, not elsewhere classified
0.655 0.345 0.000
G51.0 Bell's palsy
0.655 0.345 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.655 0.345 0.000
S90 Superficial injury of ankle and foot
0.654 0.346 0.000
I35.0 Aortic (valve) stenosis
0.654 0.346 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.653 0.346 0.000
I45.4 Nonspecific intraventricular block
0.653 0.347 0.000
I45.0 Right fascicular block
0.653 0.347 0.000
S01.7 Multiple open wounds of head
0.652 0.348 0.000
R52 Pain, not elsewhere classified
0.652 0.348 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.652 0.348 0.000
G23 Other degenerative diseases of basal ganglia
0.651 0.348 0.000
G21 Secondary Parkinsonism
0.651 0.348 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.651 0.348 0.000
G22 Parkinsonism in diseases classified elsewhere
0.651 0.348 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.651 0.349 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.650 0.349 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.650 0.349 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.650 0.349 0.000
S01.2 Open wound of nose
0.650 0.350 0.000
G50 Disorders of trigeminal nerve
0.650 0.350 0.000
I77 Other disorders of arteries and arterioles
0.649 0.351 0.000
Q00-Q07 Congenital malformations of the nervous system
0.648 0.352 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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