TreeWAS – Variant ID: rs8092503

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H92.0 Otalgia	0.761	0.239	0.000
H92 Otalgia and effusion of ear	0.754	0.246	0.000
H92.1 Otorrhoea	0.712	0.288	0.000
H90-H95 Other disorders of ear	0.710	0.290	0.000
H90 Conductive and sensorineural hearing loss	0.645	0.355	0.000
H93 Other disorders of ear, not elsewhere classified	0.644	0.356	0.000
H92.2 Otorrhagia	0.611	0.388	0.000
H91 Other hearing loss	0.603	0.397	0.000
H90.3 Sensorineural hearing loss, bilateral	0.594	0.406	0.000
H93.1 Tinnitus	0.575	0.425	0.000
H93.9 Disorder of ear, unspecified	0.562	0.438	0.000
H90.2 Conductive hearing loss, unspecified	0.542	0.458	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.524	0.476	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.521	0.479	0.000
H91.1 Presbycusis	0.521	0.479	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.514	0.486	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.509	0.491	0.000
H93.2 Other abnormal auditory perceptions	0.491	0.508	0.000
H91.8 Other specified hearing loss	0.464	0.536	0.000
H93.3 Disorders of acoustic nerve	0.462	0.538	0.000
H93.0 Degenerative and vascular disorders of ear	0.462	0.538	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.459	0.541	0.000
H91.3 Deaf mutism, not elsewhere classified	0.451	0.549	0.000
H91.0 Ototoxic hearing loss	0.432	0.567	0.000
H91.9 Hearing loss, unspecified	0.428	0.572	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.418	0.582	0.000
H90.0 Conductive hearing loss, bilateral	0.410	0.590	0.000
H95.1 Other disorders following mastoidectomy	0.408	0.592	0.000
H91.2 Sudden idiopathic hearing loss	0.389	0.611	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.385	0.615	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.369	0.631	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.369	0.631	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.365	0.635	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.365	0.635	0.000
H90.5 Sensorineural hearing loss, unspecified	0.364	0.636	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.322	0.678	0.000
H93.8 Other specified disorders of ear	0.317	0.683	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.806	0.194
Chapter VIII Diseases of the ear and mastoid process	0.141	0.859	0.000
H65-H75 Diseases of middle ear and mastoid	0.098	0.902	0.000
H73 Other disorders of tympanic membrane	0.086	0.914	0.000
H60-H62 Diseases of external ear	0.080	0.920	0.000
H69 Other disorders of Eustachian tube	0.075	0.925	0.000
H73.8 Other specified disorders of tympanic membrane	0.075	0.925	0.000
H70 Mastoiditis and related conditions	0.075	0.925	0.000
H65 Nonsuppurative otitis media	0.075	0.925	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.071	0.929	0.000
H68 Eustachian salpingitis and obstruction	0.071	0.929	0.000
H67 Otitis media in diseases classified elsewhere	0.071	0.929	0.000
H80-H83 Diseases of inner ear	0.070	0.930	0.000
H65.3 Chronic mucoid otitis media	0.070	0.930	0.000
H72 Perforation of tympanic membrane	0.070	0.930	0.000
H73.1 Chronic myringitis	0.068	0.932	0.000
H72.0 Central perforation of tympanic membrane	0.063	0.937	0.000
H73.0 Acute myringitis	0.062	0.938	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.060	0.940	0.000
H69.8 Other specified disorders of Eustachian tube	0.060	0.940	0.000
H74 Other disorders of middle ear and mastoid	0.058	0.942	0.000
H65.2 Chronic serous otitis media	0.057	0.943	0.000
H65.1 Other acute nonsuppurative otitis media	0.057	0.943	0.000
H66 Suppurative and unspecified otitis media	0.057	0.943	0.000
H70.9 Mastoiditis, unspecified	0.057	0.943	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.057	0.943	0.000
H70.8 Other mastoiditis and related conditions	0.055	0.945	0.000
H72.8 Other perforations of tympanic membrane	0.055	0.945	0.000
H69.0 Patulous Eustachian tube	0.054	0.946	0.000
H70.2 Petrositis	0.054	0.946	0.000
H70.1 Chronic mastoiditis	0.054	0.946	0.000
H70.0 Acute mastoiditis	0.054	0.946	0.000
H69.9 Eustachian tube disorder, unspecified	0.053	0.946	0.000
F33 Recurrent depressive disorder	0.000	0.948	0.052
H61 Other disorders of external ear	0.052	0.948	0.000
H80 Otosclerosis	0.052	0.948	0.000
H61.2 Impacted cerumen	0.052	0.948	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.051	0.949	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.051	0.949	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.051	0.949	0.000
H68.1 Obstruction of Eustachian tube	0.051	0.949	0.000
H68.0 Eustachian salpingitis	0.051	0.949	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.051	0.949	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.051	0.949	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.949	0.051
H82 Vertiginous syndromes in diseases classified elsewhere	0.050	0.949	0.000
F30-F39 Mood [affective] disorders	0.000	0.950	0.050
F33.9 Recurrent depressive disorder, unspecified	0.000	0.950	0.050
H65.0 Acute serous otitis media	0.049	0.950	0.000
H71 Cholesteatoma of middle ear	0.049	0.951	0.000
F31 Bipolar affective disorder	0.000	0.951	0.049
H72.2 Other marginal perforations of tympanic membrane	0.048	0.952	0.000
H60 Otitis externa	0.047	0.953	0.000
F39 Unspecified mood [affective] disorder	0.000	0.954	0.046
H74.1 Adhesive middle ear disease	0.045	0.954	0.000
H72.1 Attic perforation of tympanic membrane	0.045	0.955	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.956	0.044
F31.9 Bipolar affective disorder, unspecified	0.000	0.956	0.044
H81 Disorders of vestibular function	0.044	0.956	0.000
H66.9 Otitis media, unspecified	0.044	0.956	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.044	0.956	0.000
F32 Depressive episode	0.000	0.957	0.043
H66.1 Chronic tubotympanic suppurative otitis media	0.043	0.957	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.957	0.043
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.957	0.043
H74.0 Tympanosclerosis	0.042	0.958	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.042	0.958	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.041	0.959	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.041	0.959	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.041	0.959	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.041	0.959	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.041	0.959	0.000
H62.2 Otitis externa in mycoses	0.041	0.959	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.041	0.959	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.040	0.960	0.000
H66.4 Suppurative otitis media, unspecified	0.039	0.960	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.961	0.039
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.961	0.039
H80.9 Otosclerosis, unspecified	0.039	0.961	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.962	0.038
F32.9 Depressive episode, unspecified	0.000	0.962	0.038
H66.0 Acute suppurative otitis media	0.038	0.962	0.000
F33.8 Other recurrent depressive disorders	0.000	0.962	0.038
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.962	0.038
H80.8 Other otosclerosis	0.037	0.962	0.000
H80.2 Cochlear otosclerosis	0.037	0.962	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.037	0.962	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.037	0.962	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.037	0.962	0.000
H60.4 Cholesteatoma of external ear	0.037	0.963	0.000
H61.1 Non-infective disorders of pinna	0.037	0.963	0.000
F34 Persistent mood [affective] disorders	0.000	0.963	0.037
F38 Other mood [affective] disorders	0.000	0.964	0.036
H60.9 Otitis externa, unspecified	0.036	0.964	0.000
F32.8 Other depressive episodes	0.000	0.964	0.035
F31.8 Other bipolar affective disorders	0.000	0.965	0.035
H81.3 Other peripheral vertigo	0.035	0.965	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.966	0.034
H74.4 Polyp of middle ear	0.034	0.966	0.000
H60.8 Other otitis externa	0.034	0.966	0.000
H60.2 Malignant otitis externa	0.033	0.966	0.000
H81.9 Disorder of vestibular function, unspecified	0.033	0.967	0.000
H81.8 Other disorders of vestibular function	0.033	0.967	0.000
H60.0 Abscess of external ear	0.033	0.967	0.000
F30 Manic episode	0.000	0.967	0.033
H74.8 Other specified disorders of middle ear and mastoid	0.032	0.967	0.000
H60.3 Other infective otitis externa	0.032	0.968	0.000
H61.8 Other specified disorders of external ear	0.032	0.968	0.000
H81.4 Vertigo of central origin	0.032	0.968	0.000
H81.2 Vestibular neuronitis	0.032	0.968	0.000
H81.0 Meniere's disease	0.031	0.969	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.969	0.031
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.969	0.031
H65.4 Other chronic nonsuppurative otitis media	0.030	0.969	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.970	0.030
H61.9 Disorder of external ear, unspecified	0.029	0.971	0.000
H83 Other diseases of inner ear	0.029	0.971	0.000
F32.0 Mild depressive episode	0.000	0.971	0.029
H60.5 Acute otitis externa, non-infective	0.027	0.973	0.000
F34.1 Dysthymia	0.000	0.973	0.027
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.973	0.026
F34.8 Other persistent mood [affective] disorders	0.000	0.973	0.026
F34.0 Cyclothymia	0.000	0.973	0.026
F30.9 Manic episode, unspecified	0.000	0.973	0.026
F38.8 Other specified mood [affective] disorders	0.000	0.974	0.026
F38.1 Other recurrent mood [affective] disorders	0.000	0.974	0.026
F38.0 Other single mood [affective] disorders	0.000	0.974	0.026
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.974	0.026
H66.3 Other chronic suppurative otitis media	0.026	0.974	0.000
F30.0 Hypomania	0.000	0.975	0.025
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.976	0.024
F30.8 Other manic episodes	0.000	0.976	0.024
F32.1 Moderate depressive episode	0.000	0.977	0.023
H61.3 Acquired stenosis of external ear canal	0.022	0.977	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.978	0.022
H60.1 Cellulitis of external ear	0.022	0.978	0.000
H83.9 Disease of inner ear, unspecified	0.021	0.979	0.000
H83.3 Noise effects on inner ear	0.021	0.979	0.000
H83.2 Labyrinthine dysfunction	0.021	0.979	0.000
H83.1 Labyrinthine fistula	0.021	0.979	0.000
F30.1 Mania without psychotic symptoms	0.000	0.980	0.020
H83.8 Other specified diseases of inner ear	0.019	0.980	0.000
F30.2 Mania with psychotic symptoms	0.000	0.982	0.017
K86.9 Disease of pancreas, unspecified	0.014	0.986	0.000
H81.1 Benign paroxysmal vertigo	0.012	0.988	0.000
H61.0 Perichondritis of external ear	0.011	0.988	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.011	0.989	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.991	0.009
Z43.2 Attention to ileostomy	0.009	0.991	0.000
K86.8 Other specified diseases of pancreas	0.009	0.991	0.000
K29.1 Other acute gastritis	0.000	0.992	0.008
I74.5 Embolism and thrombosis of iliac artery	0.000	0.992	0.008
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.993	0.007
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.993	0.007
T39.0 Salicylates	0.000	0.993	0.007
K86 Other diseases of pancreas	0.007	0.993	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.994	0.006
B00.1 Herpesviral vesicular dermatitis	0.006	0.994	0.000
K86.2 Cyst of pancreas	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.994	0.006
I49.3 Ventricular premature depolarisation	0.000	0.994	0.006
I74 Arterial embolism and thrombosis	0.000	0.995	0.005
B00.5 Herpesviral ocular disease	0.005	0.995	0.000
B00 Herpesviral [herpes simplex] infections	0.005	0.995	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.995	0.005
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
T40.4 Other synthetic narcotics	0.000	0.995	0.005
Z43.5 Attention to cyctostomy	0.005	0.995	0.000
I49 Other cardiac arrhythmias	0.000	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
I49.1 Atrial premature depolarisation	0.000	0.995	0.005
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.995	0.005
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.995	0.005
A63.0 Anogenital (venereal) warts	0.004	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.996	0.004
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.996	0.004
I74.8 Embolism and thrombosis of other arteries	0.000	0.996	0.004
T39.4 Antirheumatics, not elsewhere classified	0.000	0.996	0.004
T39.2 Pyrazolone derivatives	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
B00.9 Herpesviral infection, unspecified	0.004	0.996	0.000
T40.2 Other opioids	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
K41 Femoral hernia	0.000	0.996	0.004
Z43 Attention to artificial openings	0.004	0.996	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.996	0.004
I49.0 Ventricular fibrillation and flutter	0.000	0.996	0.004
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.004	0.996	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.996	0.004
B00.8 Other forms of herpesviral infection	0.004	0.996	0.000
B00.7 Disseminated herpesviral disease	0.004	0.996	0.000
B00.3 Herpesviral meningitis	0.004	0.996	0.000
B00.0 Eczema herpeticum	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
Z43.0 Attention to tracheostomy	0.004	0.996	0.000
B00.4 Herpesviral encephalitis	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.000	0.996	0.004
C77.3 Axillary and upper limb lymph nodes	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.996	0.004
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.996	0.004
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.996	0.004
K86.3 Pseudocyst of pancreas	0.004	0.996	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.996	0.004
I49.2 Junctional premature depolarisation	0.000	0.996	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.003
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.003
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.996	0.003
T40.8 Lysergide [LSD]	0.000	0.996	0.003
T40.7 Cannabis (derivatives)	0.000	0.996	0.003
T40.5 Cocaine	0.000	0.996	0.003
T40.3 Methadone	0.000	0.996	0.003
T40.1 Heroin	0.000	0.996	0.003
T40.0 Opium	0.000	0.996	0.003
E73.9 Lactose intolerance, unspecified	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
R80 Isolated proteinuria	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.997	0.003
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.997	0.003
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.997	0.003
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
Z43.9 Attention to unspecified artificial opening	0.003	0.997	0.000
Z43.7 Attention to artificial vagina	0.003	0.997	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
C80.9 Malignant neoplasm, unspecified	0.003	0.997	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
T47.7 Emetics	0.000	0.997	0.003
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.003
T47.5 Digestants	0.000	0.997	0.003
T47.4 Other laxatives	0.000	0.997	0.003
T47.3 Saline and osmotic laxatives	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
H83.0 Labyrinthitis	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
S82.20 Fracture of shaft of tibia (closed)	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
T46.7 Peripheral vasodilators	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
Z43.6 Attention to other artificial openings of urinary tract	0.003	0.997	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.003	0.997	0.000
M47.9 Spondylosis, unspecified	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
N81.5 Vaginal enterocele	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.5 Anti-common-cold drugs	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
C25.0 Head of pancreas	0.003	0.997	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.997	0.003
C25.2 Tail of pancreas	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
Z43.3 Attention to colostomy	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.002
T49.8 Other topical agents	0.000	0.997	0.002
T49.7 Dental drugs, topically applied	0.000	0.997	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.002
T49.2 Local astringents and local detergents	0.000	0.997	0.002
T49.1 Antipruritics	0.000	0.997	0.002
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.002
T38.7 Androgens and anabolic congeners	0.000	0.997	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.002
T38.5 Other oestrogens and progestogens	0.000	0.997	0.002
T38.4 Oral contraceptives	0.000	0.997	0.002
T38.2 Antithyroid drugs	0.000	0.997	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.002
T45.5 Anticoagulants	0.000	0.997	0.002
Z43.4 Attention to other artificial openings of digestive tract	0.002	0.997	0.000
O66 Other obstructed labour	0.003	0.997	0.000
R25.1 Tremor, unspecified	0.000	0.997	0.003
A63.8 Other specified predominantly sexually transmitted diseases	0.002	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.002
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.997	0.003
J92.0 Pleural plaque with presence of asbestos	0.000	0.997	0.003
Y87.1 Sequelae of assault	0.000	0.997	0.002
N13.6 Pyonephrosis	0.000	0.997	0.002
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
B44.1 Other pulmonary aspergillosis	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.000	0.998	0.002
Z43.1 Attention to gastrostomy	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
Y85 Sequelae of transport accidents	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
F45.8 Other somatoform disorders	0.000	0.998	0.002
Z43.8 Attention to other artificial openings	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.001	0.998	0.002
B37.9 Candidiasis, unspecified	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.002	0.998	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.998	0.002
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.002	0.998	0.000
T42.4 Benzodiazepines	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
C25.1 Body of pancreas	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
O66.9 Obstructed labour, unspecified	0.002	0.998	0.000
O66.8 Other specified obstructed labour	0.002	0.998	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.002	0.998	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.998	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.000	0.998	0.002
Z01.6 Radiological examination, not elsewhere classified	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.998	0.002
B17.1 Acute hepatitis C	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.998	0.002
T42.1 Iminostilbenes	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
S06 Intracranial injury	0.000	0.998	0.002
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
F40.2 Specific (isolated) phobias	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.000	0.998	0.002
Y89 Sequelae of other external causes	0.000	0.998	0.002
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
M87.8 Other osteonecrosis	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
Y88 Sequelae of surgical and medical care as external cause	0.000	0.998	0.002
M24.09 Loose body in joint (Site unspecified)	0.002	0.998	0.000
M24.08 Loose body in joint (Other)	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
C25.3 Pancreatic duct	0.002	0.998	0.000
Y87.2 Sequelae of events of undetermined intent	0.000	0.998	0.002
Y87.0 Sequelae of intentional self-harm	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.002	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
N60.9 Benign mammary dysplasia, unspecified	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.000	0.998	0.002
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations