TreeWAS – Variant ID: rs8176742

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.000	1.000
I80 Phlebitis and thrombophlebitis	0.000	0.002	0.998
Z86.7 Personal history of diseases of the circulatory system	0.000	0.014	0.986
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.019	0.981
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.045	0.955
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.093	0.907
I82 Other venous embolism and thrombosis	0.000	0.123	0.877
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.130	0.870
I82.8 Embolism and thrombosis of other specified veins	0.000	0.135	0.865
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.160	0.840
I85 Oesophageal varices	0.000	0.176	0.824
I86 Varicose veins of other sites	0.000	0.226	0.774
I87 Other disorders of veins	0.000	0.233	0.767
I81 Portal vein thrombosis	0.000	0.262	0.738
I85.9 Oesophageal varices without bleeding	0.000	0.265	0.735
I85.0 Oesophageal varices with bleeding	0.000	0.332	0.668
I87.1 Compression of vein	0.000	0.336	0.664
I86.4 Gastric varices	0.000	0.338	0.662
I86.8 Varicose veins of other specified sites	0.000	0.365	0.634
I82.1 Thrombophlebitis migrans	0.000	0.371	0.628
I82.0 Budd-Chiari syndrome	0.000	0.371	0.628
I88 Nonspecific lymphadenitis	0.000	0.400	0.600
I82.3 Embolism and thrombosis of renal vein	0.000	0.409	0.591
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.428	0.572
I82.2 Embolism and thrombosis of vena cava	0.000	0.436	0.564
I87.8 Other specified disorders of veins	0.000	0.442	0.558
I86.3 Vulval varices	0.000	0.445	0.555
I86.0 Sublingual varices	0.000	0.445	0.555
I83 Varicose veins of lower extremities	0.000	0.445	0.555
I87.9 Disorder of vein, unspecified	0.000	0.450	0.550
I87.0 Postphlebitic syndrome	0.000	0.450	0.550
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.454	0.546
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.462	0.538
I86.2 Pelvic varices	0.000	0.465	0.535
I86.1 Scrotal varices	0.000	0.495	0.505
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.499	0.501
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.555	0.445
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.565	0.435
I88.8 Other nonspecific lymphadenitis	0.000	0.570	0.430
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.570	0.430
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.581	0.419
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.594	0.406
I26 Pulmonary embolism	0.000	0.605	0.395
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.615	0.385
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.627	0.372
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.693	0.307
I89.1 Lymphangitis	0.000	0.736	0.264
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.761	0.239
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.782	0.217
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.818	0.182
I89.0 Lymphoedema, not elsewhere classified	0.000	0.826	0.174
I83.0 Varicose veins of lower extremities with ulcer	0.001	0.829	0.171
Chapter IX Diseases of the circulatory system	0.000	0.873	0.127
I28 Other diseases of pulmonary vessels	0.000	0.879	0.121
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.892	0.108
Z86 Personal history of certain other diseases	0.000	0.897	0.103
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.898	0.102
I00-I02 Acute rheumatic fever	0.000	0.909	0.091
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.913	0.087
I28.1 Aneurysm of pulmonary artery	0.000	0.913	0.087
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.913	0.087
I28.8 Other specified diseases of pulmonary vessels	0.000	0.922	0.078
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.925	0.075
I05-I09 Chronic rheumatic heart diseases	0.000	0.930	0.070
I02 Rheumatic chorea	0.000	0.934	0.065
I01 Rheumatic fever with heart involvement	0.000	0.934	0.065
I00 Rheumatic fever without mention of heart involvement	0.000	0.934	0.065
M79.8 Other specified soft tissue disorders	0.000	0.937	0.063
I27 Other pulmonary heart diseases	0.000	0.940	0.060
I09 Other rheumatic heart diseases	0.000	0.943	0.057
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.944	0.056
I05 Rheumatic mitral valve diseases	0.000	0.945	0.055
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.945	0.055
M79.88 Other specified soft tissue disorders (Other)	0.000	0.949	0.051
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.949	0.050
I05.9 Mitral valve disease, unspecified	0.000	0.950	0.050
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.952	0.048
I06 Rheumatic aortic valve diseases	0.000	0.952	0.047
I09.9 Rheumatic heart disease, unspecified	0.000	0.952	0.047
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.953	0.047
I01.8 Other acute rheumatic heart disease	0.000	0.953	0.047
I01.2 Acute rheumatic myocarditis	0.000	0.953	0.047
I01.1 Acute rheumatic endocarditis	0.000	0.953	0.047
I01.0 Acute rheumatic pericarditis	0.000	0.953	0.047
I02.9 Rheumatic chorea without heart involvement	0.000	0.953	0.047
I02.0 Rheumatic chorea with heart involvement	0.000	0.953	0.047
I27.8 Other specified pulmonary heart diseases	0.000	0.953	0.046
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.955	0.045
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.956	0.044
I05.0 Mitral stenosis	0.000	0.957	0.043
I27.1 Kyphoscoliotic heart disease	0.000	0.957	0.043
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.957	0.043
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.958	0.042
I09.8 Other specified rheumatic heart diseases	0.000	0.959	0.041
I09.2 Chronic rheumatic pericarditis	0.000	0.959	0.041
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.959	0.041
I09.0 Rheumatic myocarditis	0.000	0.959	0.041
H72 Perforation of tympanic membrane	0.000	0.959	0.041
H72.8 Other perforations of tympanic membrane	0.000	0.960	0.040
I05.2 Mitral stenosis with insufficiency	0.000	0.961	0.039
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.961	0.039
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.962	0.038
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.963	0.037
I07 Rheumatic tricuspid valve diseases	0.000	0.965	0.035
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.966	0.034
I06.8 Other rheumatic aortic valve diseases	0.000	0.966	0.034
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.966	0.034
I06.1 Rheumatic aortic insufficiency	0.000	0.966	0.034
I05.8 Other mitral valve diseases	0.000	0.967	0.032
I27.0 Primary pulmonary hypertension	0.000	0.968	0.032
H72.1 Attic perforation of tympanic membrane	0.000	0.968	0.032
I05.1 Rheumatic mitral insufficiency	0.000	0.968	0.032
I06.0 Rheumatic aortic stenosis	0.000	0.968	0.032
H65-H75 Diseases of middle ear and mastoid	0.000	0.971	0.029
H72.2 Other marginal perforations of tympanic membrane	0.000	0.971	0.029
H72.0 Central perforation of tympanic membrane	0.000	0.971	0.029
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.972	0.028
H74 Other disorders of middle ear and mastoid	0.000	0.972	0.028
I08 Multiple valve diseases	0.000	0.972	0.028
I27.9 Pulmonary heart disease, unspecified	0.000	0.973	0.027
H65.3 Chronic mucoid otitis media	0.000	0.973	0.027
I07.9 Tricuspid valve disease, unspecified	0.000	0.974	0.025
I07.8 Other tricuspid valve diseases	0.000	0.974	0.025
I07.2 Tricuspid stenosis with insufficiency	0.000	0.974	0.025
I07.0 Tricuspid stenosis	0.000	0.974	0.025
H65 Nonsuppurative otitis media	0.000	0.975	0.025
H74.0 Tympanosclerosis	0.000	0.975	0.025
I27.2 Other secondary pulmonary hypertension	0.000	0.976	0.024
H74.4 Polyp of middle ear	0.000	0.976	0.024
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.976	0.023
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.977	0.023
H74.1 Adhesive middle ear disease	0.000	0.977	0.023
H66 Suppurative and unspecified otitis media	0.000	0.977	0.023
I10-I15 Hypertensive diseases	0.000	0.977	0.023
I08.8 Other multiple valve diseases	0.000	0.978	0.022
Z92.1 Personal history of long-term (current) use of anticoagulants	0.000	0.978	0.022
I20-I25 Ischaemic heart diseases	0.000	0.978	0.022
H70 Mastoiditis and related conditions	0.000	0.979	0.021
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.979	0.021
H68 Eustachian salpingitis and obstruction	0.000	0.979	0.021
H67 Otitis media in diseases classified elsewhere	0.000	0.979	0.021
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.980	0.020
H71 Cholesteatoma of middle ear	0.000	0.980	0.020
H66.9 Otitis media, unspecified	0.000	0.981	0.019
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.981	0.019
I08.9 Multiple valve disease, unspecified	0.000	0.981	0.019
H66.3 Other chronic suppurative otitis media	0.000	0.981	0.019
I22 Subsequent myocardial infarction	0.000	0.981	0.019
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.981	0.019
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.981	0.018
H65.4 Other chronic nonsuppurative otitis media	0.000	0.982	0.018
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.982	0.018
H65.1 Other acute nonsuppurative otitis media	0.000	0.982	0.018
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.982	0.018
H69 Other disorders of Eustachian tube	0.000	0.983	0.017
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.983	0.017
H66.4 Suppurative otitis media, unspecified	0.000	0.983	0.016
I23 Certain current complications following acute myocardial infarction	0.000	0.984	0.016
I13 Hypertensive heart and renal disease	0.000	0.984	0.016
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.984	0.016
H65.0 Acute serous otitis media	0.000	0.984	0.016
I22.8 Subsequent myocardial infarction of other sites	0.000	0.984	0.016
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.984	0.016
H70.9 Mastoiditis, unspecified	0.000	0.984	0.016
H65.2 Chronic serous otitis media	0.000	0.984	0.016
I11 Hypertensive heart disease	0.000	0.984	0.016
H70.8 Other mastoiditis and related conditions	0.000	0.984	0.015
H70.2 Petrositis	0.000	0.984	0.015
H70.0 Acute mastoiditis	0.000	0.984	0.015
H66.0 Acute suppurative otitis media	0.000	0.985	0.015
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.985	0.015
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.985	0.015
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.985	0.015
H68.1 Obstruction of Eustachian tube	0.000	0.985	0.015
H68.0 Eustachian salpingitis	0.000	0.985	0.015
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.985	0.015
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.985	0.015
H70.1 Chronic mastoiditis	0.000	0.985	0.015
A04.7 Enterocolitis due to Clostridium difficile	0.015	0.985	0.000
I15 Secondary hypertension	0.000	0.985	0.015
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.985	0.015
I97.0 Postcardiotomy syndrome	0.000	0.985	0.015
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.985	0.014
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.986	0.014
H73 Other disorders of tympanic membrane	0.000	0.986	0.014
I65.2 Occlusion and stenosis of carotid artery	0.000	0.986	0.014
I24 Other acute ischaemic heart diseases	0.000	0.986	0.014
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.986	0.013
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.986	0.013
I98.0 Cardiovascular syphilis	0.000	0.986	0.013
A04 Other bacterial intestinal infections	0.014	0.986	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.987	0.013
I97.1 Other functional disturbances following cardiac surgery	0.000	0.987	0.013
A04.5 Campylobacter enteritis	0.013	0.987	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.013	0.987	0.000
H69.0 Patulous Eustachian tube	0.000	0.987	0.013
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.987	0.013
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.013	0.987	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.987	0.012
I21 Acute myocardial infarction	0.000	0.988	0.012
Q38 Other congenital malformations of tongue, mouth and pharynx	0.012	0.988	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.988	0.012
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.988	0.012
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.988	0.012
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.988	0.012
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.988	0.012
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.988	0.012
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.988	0.012
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.988	0.012
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.988	0.012
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.988	0.012
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.988	0.012
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.988	0.012
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.988	0.012
I24.8 Other forms of acute ischaemic heart disease	0.000	0.988	0.012
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.012	0.988	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.988	0.012
I24.1 Dressler's syndrome	0.000	0.989	0.011
Q45 Other congenital malformations of digestive system	0.011	0.989	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.011	0.989	0.000
Q43 Other congenital malformations of intestine	0.011	0.989	0.000
I15.8 Other secondary hypertension	0.000	0.989	0.011
I15.2 Hypertension secondary to endocrine disorders	0.000	0.989	0.011
I15.0 Renovascular hypertension	0.000	0.989	0.011
I60-I69 Cerebrovascular diseases	0.000	0.989	0.011
A04.4 Other intestinal Escherichia coli infections	0.011	0.989	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.989	0.011
Q50-Q56 Congenital malformations of genital organs	0.011	0.989	0.000
A04.9 Bacterial intestinal infection, unspecified	0.011	0.989	0.000
Q40 Other congenital malformations of upper alimentary tract	0.011	0.989	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.989	0.011
I07.1 Tricuspid insufficiency	0.000	0.989	0.010
I15.9 Seconday hypertension, unspecified	0.000	0.990	0.010
H73.0 Acute myringitis	0.000	0.990	0.010
A00-A09 Intestinal infectious diseases	0.010	0.990	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.010	0.990	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.990	0.010
Q38.5 Congenital malformations of palate, not elsewhere classified	0.010	0.990	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.990	0.010
O16 Unspecified maternal hypertension	0.010	0.990	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.990	0.010
Q38.1 Ankyloglossia	0.010	0.990	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.010	0.990	0.000
Q38.6 Other congenital malformations of mouth	0.010	0.990	0.000
Q12 Congenital lens malformations	0.010	0.990	0.000
Q35-Q37 Cleft lip and cleft palate	0.010	0.990	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.010	0.990	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.010	0.990	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.010	0.990	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.010	0.990	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.010	0.990	0.000
Q39 Congenital malformations of oesophagus	0.010	0.990	0.000
Q52 Other congenital malformations of female genitalia	0.010	0.990	0.000
Q45.8 Other specified congenital malformations of digestive system	0.010	0.990	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.010	0.990	0.000
Q00-Q07 Congenital malformations of the nervous system	0.010	0.990	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.990	0.009
Q38.0 Congenital malformations of lips, not elsewhere classified	0.010	0.990	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.010	0.990	0.000
Q17 Other congenital malformations of ear	0.010	0.990	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.990	0.010
Q42 Congenital absence, atresia and stenosis of large intestine	0.010	0.990	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.010	0.990	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.010	0.990	0.000
Q76 Congenital malformations of spine and bony thorax	0.010	0.990	0.000
Q51 Congenital malformations of uterus and cervix	0.010	0.990	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.991	0.009
Q60-Q64 Congenital malformations of the urinary system	0.009	0.991	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.009	0.991	0.000
H73.1 Chronic myringitis	0.000	0.991	0.009
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.009	0.991	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.991	0.009
B17.1 Acute hepatitis C	0.009	0.991	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.991	0.009
Q68 Other congenital musculoskeletal deformities	0.009	0.991	0.000
Q38.8 Other congenital malformations of pharynx	0.009	0.991	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.009	0.991	0.000
Q38.3 Other congenital malformations of tongue	0.009	0.991	0.000
Q38.2 Macroglossia	0.009	0.991	0.000
Q43.0 Meckel's diverticulum	0.009	0.991	0.000
Q12.0 Congenital cataract	0.009	0.991	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.009	0.991	0.000
Q78 Other osteochondrodysplasias	0.009	0.991	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.009	0.991	0.000
Q43.3 Congenital malformations of intestinal fixation	0.009	0.991	0.000
Q61 Cystic kidney disease	0.009	0.991	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.991	0.009
Q16 Congenital malformations of ear causing impairment of hearing	0.009	0.991	0.000
Q15 Other congenital malformations of eye	0.009	0.991	0.000
Q13 Congenital malformations of anterior segment of eye	0.009	0.991	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.009	0.991	0.000
Q80-Q89 Other congenital malformations	0.009	0.991	0.000
Q51.3 Bicornate uterus	0.009	0.991	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.009	0.991	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.991	0.009
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.991	0.008
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.991	0.008
A09.9 Gastroenteritis and colitis of unspecified origin	0.009	0.991	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.991	0.008
Q10.0 Congenital ptosis	0.008	0.991	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.008	0.991	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.008	0.991	0.000
Q61.3 Polycystic kidney, unspecified	0.009	0.991	0.000
Q14 Congenital malformations of posterior segment of eye	0.008	0.991	0.000
Q17.5 Prominent ear	0.008	0.992	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.992	0.008
A02 Other Salmonella infections	0.008	0.992	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.008	0.992	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.008	0.992	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.008	0.992	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.008	0.992	0.000
Q45.2 Congenital pancreatic cyst	0.008	0.992	0.000
Q45.1 Annular pancreas	0.008	0.992	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.008	0.992	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.992	0.008
Q75 Other congenital malformations of skull and face bones	0.008	0.992	0.000
Q73 Reduction defects of unspecified limb	0.008	0.992	0.000
Q72 Reduction defects of lower limb	0.008	0.992	0.000
Q71 Reduction defects of upper limb	0.008	0.992	0.000
Q70 Syndactyly	0.008	0.992	0.000
Q69 Polydactyly	0.008	0.992	0.000
Q40.2 Other specified congenital malformations of stomach	0.008	0.992	0.000
Q43.7 Persistent cloaca	0.008	0.992	0.000
Q43.6 Congenital fistula of rectum and anus	0.008	0.992	0.000
Q43.5 Ectopic anus	0.008	0.992	0.000
Q43.4 Duplication of intestine	0.008	0.992	0.000
Q43.2 Other congenital functional disorders of colon	0.008	0.992	0.000
Q43.1 Hirschsprung's disease	0.008	0.992	0.000
Q07 Other congenital malformations of nervous system	0.008	0.992	0.000
Q31 Congenital malformations of larynx	0.008	0.992	0.000
A05 Other bacterial foodborne intoxications	0.008	0.992	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.008	0.992	0.000
Q37 Cleft palate with cleft lip	0.008	0.992	0.000
I99 Other and unspecified disorders of circulatory system	0.001	0.992	0.008
Q18 Other congenital malformations of face and neck	0.008	0.992	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.992	0.008
Q90 Down's syndrome	0.008	0.992	0.000
Q52.5 Fusion of labia	0.008	0.992	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.008	0.992	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.008	0.992	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.008	0.992	0.000
Q40.1 Congenital hiatus hernia	0.008	0.992	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.008	0.992	0.000
Q74 Other congenital malformations of limb(s)	0.008	0.992	0.000
A08 Viral and other specified intestinal infections	0.008	0.992	0.000
Q39.4 Oesophageal web	0.008	0.992	0.000
I65.1 Occlusion and stenosis of basilar artery	0.000	0.992	0.008
Q55 Other congenital malformations of male genital organs	0.008	0.992	0.000
Q96 Turner's syndrome	0.008	0.992	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.992	0.008
D68.5 Primary Thrombophilia	0.000	0.992	0.008
A06 Amoebiasis	0.008	0.992	0.000
A03 Shigellosis	0.008	0.992	0.000
A01 Typhoid and paratyphoid fevers	0.008	0.992	0.000
A00 Cholera	0.008	0.992	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.992	0.008
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.008	0.992	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.008	0.992	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.008	0.992	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.008	0.992	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.008	0.992	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.008	0.992	0.000
Q79.6 Ehlers-Danlos syndrome	0.008	0.992	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.992	0.008
Q51.8 Other congenital malformations of uterus and cervix	0.008	0.992	0.000
Q38.7 Pharyngeal pouch	0.007	0.992	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.992	0.008
Q12.9 Congenital lens malformation, unspecified	0.007	0.992	0.000
Q12.8 Other congenital lens malformations	0.007	0.992	0.000
Q12.4 Spherophakia	0.007	0.992	0.000
Q12.3 Congenital aphakia	0.007	0.992	0.000
Q12.2 Coloboma of lens	0.007	0.992	0.000
Q12.1 Congenital displaced lens	0.007	0.992	0.000
Q34 Other congenital malformations of respiratory system	0.007	0.992	0.000
Q33 Congenital malformations of lung	0.007	0.992	0.000
Q32 Congenital malformations of trachea and bronchus	0.007	0.992	0.000
Q30 Congenital malformations of nose	0.007	0.992	0.000
Q36 Cleft lip	0.007	0.993	0.000
Q35 Cleft palate	0.007	0.993	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.007	0.993	0.000
Q39.8 Other congenital malformations of oesophagus	0.007	0.993	0.000
Q39.5 Congenital dilatation of oesophagus	0.007	0.993	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.007	0.993	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.007	0.993	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.007	0.993	0.000
Q39.0 Atresia of oesophagus without fistula	0.007	0.993	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.007	0.993	0.000
Q66 Congenital deformities of feet	0.007	0.993	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.007	0.993	0.000
Q52.7 Other congenital malformations of vulva	0.007	0.993	0.000
Q52.6 Congenital malformation of clitoris	0.007	0.993	0.000
Q52.4 Other congenital malformations of vagina	0.007	0.993	0.000
Q52.3 Imperforate hymen	0.007	0.993	0.000
Q52.2 Congenital rectovaginal fistula	0.007	0.993	0.000
Q52.1 Doubling of vagina	0.007	0.993	0.000
Q52.0 Congenital absence of vagina	0.007	0.993	0.000
Q03 Congenital hydrocephalus	0.007	0.993	0.000
Q10.7 Congenital malformation of orbit	0.007	0.993	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.007	0.993	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.007	0.993	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.007	0.993	0.000
Q10.3 Other congenital malformations of eyelid	0.007	0.993	0.000
Q10.2 Congenital entropion	0.007	0.993	0.000
Q10.1 Congenital ectropion	0.007	0.993	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.007	0.993	0.000
Q06 Other congenital malformations of spinal cord	0.007	0.993	0.000
Q04 Other congenital malformations of brain	0.007	0.993	0.000
Q01 Encephalocele	0.007	0.993	0.000
Q00 Anencephaly and similar malformations	0.007	0.993	0.000
Q02 Microcephaly	0.007	0.993	0.000
Q17.9 Congenital malformation of ear, unspecified	0.007	0.993	0.000
Q17.8 Other specified congenital malformations of ear	0.007	0.993	0.000
Q17.4 Misplaced ear	0.007	0.993	0.000
Q17.3 Other misshapen ear	0.007	0.993	0.000
Q17.2 Microtia	0.007	0.993	0.000
Q17.1 Macrotia	0.007	0.993	0.000
Q17.0 Accessory auricle	0.007	0.993	0.000
Q65 Congenital deformities of hip	0.007	0.993	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.007	0.993	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.007	0.993	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.007	0.993	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.007	0.993	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.007	0.993	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.007	0.993	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.007	0.993	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.007	0.993	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.007	0.993	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.007	0.993	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.007	0.993	0.000
Q78.0 Osteogenesis imperfecta	0.007	0.993	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.993	0.007
Q76.9 Congenital malformation of bony thorax, unspecified	0.007	0.993	0.000
Q76.8 Other congenital malformations of bony thorax	0.007	0.993	0.000
Q76.7 Congenital malformation of sternum	0.007	0.993	0.000
Q76.6 Other congenital malformations of ribs	0.007	0.993	0.000
Q76.5 Cervical rib	0.007	0.993	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.007	0.993	0.000
Q76.2 Congenital spondylolisthesis	0.007	0.993	0.000
Q76.1 Klippel-Feil syndrome	0.007	0.993	0.000
I67 Other cerebrovascular diseases	0.000	0.993	0.007
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.007	0.993	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.007	0.993	0.000
Q51.6 Embryonic cyst of cervix	0.007	0.993	0.000
Q51.5 Agenesis and aplasia of cervix	0.007	0.993	0.000
Q51.4 Unicornate uterus	0.007	0.993	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.007	0.993	0.000
Q51.0 Agenesis and aplasia of uterus	0.007	0.993	0.000
Q76.0 Spina bifida occulta	0.007	0.993	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.993	0.007
Q39.6 Diverticulum of oesophagus	0.007	0.993	0.000
Q61.5 Medullary cystic kidney	0.007	0.993	0.000
T78.3 Angioneurotic oedema	0.000	0.993	0.007
Q54 Hypospadias	0.007	0.993	0.000
A07 Other protozoal intestinal diseases	0.007	0.993	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.007	0.993	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.993	0.007
Y85 Sequelae of transport accidents	0.000	0.993	0.007
Q31.3 Laryngocele	0.007	0.993	0.000
Q07.8 Other specified congenital malformations of nervous system	0.007	0.993	0.000
Q51.2 Other doubling of uterus	0.007	0.993	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.993	0.007
Q61.9 Cystic kidney disease, unspecified	0.007	0.993	0.000
Q99.8 Other specified chromosome abnormalities	0.007	0.993	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.007	0.993	0.000
Q44.7 Other congenital malformations of liver	0.007	0.993	0.000
Q44.5 Other congenital malformations of bile ducts	0.007	0.993	0.000
Q44.4 Choledochal cyst	0.007	0.993	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.007	0.993	0.000
Q44.2 Atresia of bile ducts	0.007	0.993	0.000
Q44.1 Other congenital malformations of gallbladder	0.007	0.993	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.007	0.993	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.007	0.993	0.000
Z89.5 Acquired absence of leg at or below knee	0.007	0.993	0.000
I12 Hypertensive renal disease	0.000	0.993	0.007
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.007	0.993	0.000
Q79.5 Other congenital malformations of abdominal wall	0.007	0.993	0.000
Q79.4 Prune belly syndrome	0.007	0.993	0.000
Q79.3 Gastroschisis	0.007	0.993	0.000
Q79.2 Exomphalos	0.007	0.993	0.000
Q79.1 Other congenital malformations of diaphragm	0.007	0.993	0.000
Q79.0 Congenital diaphragmatic hernia	0.007	0.993	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.007	0.993	0.000
Q64 Other congenital malformations of urinary system	0.007	0.993	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.993	0.007
Q67.6 Pectus excavatum	0.007	0.993	0.000
Q53 Undescended testicle	0.007	0.993	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.993	0.007
D68 Other coagulation defects	0.000	0.993	0.007
Q68.5 Congenital bowing of long bones of leg, unspecified	0.007	0.993	0.000
Q68.4 Congenital bowing of tibia and fibula	0.007	0.993	0.000
Q68.3 Congenital bowing of femur	0.007	0.993	0.000
Q68.2 Congenital deformity of knee	0.007	0.993	0.000
Q68.1 Congenital deformity of hand	0.007	0.993	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.007	0.993	0.000
Q85 Phakomatoses, not elsewhere classified	0.007	0.993	0.000
Q67.5 Congenital deformity of spine	0.007	0.993	0.000
A02.0 Salmonella gastro-enteritis	0.007	0.993	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.007	0.993	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.006	0.993	0.000
Q78.8 Other specified osteochondrodysplasias	0.006	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations