TreeWAS – Variant ID: rs854384

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y43.3 Other antineoplastic drugs	0.021	0.979	0.000
Y43 Primarily systemic agents	0.021	0.979	0.000
Y43.0 Antiallergic and antiemetic drugs	0.019	0.980	0.000
Y43.4 Immunosuppressive agents	0.019	0.981	0.000
Y43.1 Antineoplastic antimetabolites	0.018	0.982	0.000
Y43.9 Primarily systemic agent, unspecified	0.015	0.985	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.015	0.985	0.000
Y43.6 Enzymes, not elsewhere classified	0.015	0.985	0.000
Y43.5 Acidifying and alkalising agents	0.015	0.985	0.000
Y43.2 Antineoplastic natural products	0.014	0.986	0.000
Y45.0 Opioids and related analgesics	0.013	0.987	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.013	0.987	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.012	0.988	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.012	0.988	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.012	0.988	0.000
Y48.3 Local anaesthetics	0.012	0.988	0.000
Y48 Anaesthetics and therapeutic gases	0.012	0.988	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.012	0.988	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.011	0.989	0.000
Y45.5 4-Aminophenol derivatives	0.010	0.990	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
Y44 Agents primarily affecting blood constituents	0.010	0.990	0.000
Y59 Other and unspecified vaccines and biological substances	0.010	0.990	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.010	0.990	0.000
Y45.1 Salicylates	0.010	0.990	0.000
Y58 Bacterial vaccines	0.009	0.990	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.009	0.991	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.009	0.991	0.000
Y45.4 Antirheumatics	0.009	0.991	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.009	0.991	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.991	0.000
Y41.4 Anthelminthics	0.009	0.991	0.000
Y41.3 Other antiprotozoal drugs	0.009	0.991	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.009	0.991	0.000
Y41.5 Antiviral drugs	0.009	0.991	0.000
Y41.0 Sulphonamides	0.009	0.991	0.000
Y57 Other and unspecified drugs and medicaments	0.009	0.991	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.009	0.991	0.000
Y41.1 Antimycobacterial drugs	0.009	0.991	0.000
Y48.5 Therapeutic gases	0.009	0.991	0.000
Y48.1 Parenteral anaesthetics	0.009	0.991	0.000
Y48.0 Inhaled anaesthetics	0.009	0.991	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.009	0.991	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.009	0.991	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.009	0.991	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.009	0.991	0.000
Y51.0 Anticholinesterase agents	0.009	0.991	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.991	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.008	0.991	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.008	0.992	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.992	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.992	0.000
Y48.4 Anaesthetic, unspecified	0.008	0.992	0.000
Y59.3 Immunoglobulin	0.008	0.992	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.008	0.992	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.008	0.992	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.992	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
Y48.2 Other and unspecified general anaesthetics	0.008	0.992	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.008	0.992	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.007	0.992	0.000
D23.1 Skin of eyelid, including canthus	0.008	0.992	0.000
Y44.6 Natural blood and blood products	0.007	0.992	0.000
Y52 Agents primarily affecting the cardiovascular system	0.008	0.992	0.000
H57.8 Other specified disorders of eye and adnexa	0.008	0.992	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.992	0.000
Y42.2 Antithyroid drugs	0.007	0.992	0.000
Y46.6 Other and unspecified antiepileptics	0.007	0.992	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.007	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.007	0.993	0.000
Y44.7 Plasma substitutes	0.007	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.007	0.993	0.000
Y59.9 Vaccine or biological substance, unspecified	0.007	0.993	0.000
Y59.8 Other specified vaccines and biological substances	0.007	0.993	0.000
Y59.2 Protozoal vaccines	0.007	0.993	0.000
Y59.1 Rickettsial vaccines	0.007	0.993	0.000
Y44.2 Anticoagulants	0.007	0.993	0.000
H57 Other disorders of eye and adnexa	0.007	0.993	0.000
Y42.7 Androgens and anabolic congeners	0.007	0.993	0.000
Y57.8 Other drugs and medicaments	0.007	0.993	0.000
Y46.7 Anti-Parkinsonism drugs	0.007	0.993	0.000
Y45.2 Propionic acid derivatives	0.007	0.993	0.000
Y58.9 Other and unspecified bacterial vaccines	0.007	0.993	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.007	0.993	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.007	0.993	0.000
Y58.5 Diphtheria vaccine	0.007	0.993	0.000
Y58.4 Tetanus vaccine	0.007	0.993	0.000
Y58.3 Plague vaccine	0.007	0.993	0.000
Y58.2 Cholera vaccine	0.007	0.993	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.007	0.993	0.000
Y54.5 Other diuretics	0.007	0.993	0.000
Y46.8 Antispasticity drugs	0.007	0.993	0.000
Y46.3 Deoxybarbiturates	0.007	0.993	0.000
Y46.1 Oxazolidinediones	0.007	0.993	0.000
Y46.0 Succinimides	0.007	0.993	0.000
Y50.9 Central nervous system stimulant, unspecified	0.007	0.993	0.000
Y50.8 Other central nervous system stimulants	0.007	0.993	0.000
Y50.1 Opioid receptor antagonists	0.007	0.993	0.000
Y50.0 Analeptics	0.007	0.993	0.000
Y58.0 BCG vaccine	0.007	0.993	0.000
Y46.5 Valproic acid	0.007	0.993	0.000
Y53.2 Stimulant laxatives	0.007	0.993	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.007	0.993	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.007	0.993	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.007	0.993	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.007	0.993	0.000
Y47.4 Bromine compounds	0.007	0.993	0.000
Y47.3 Paraldehyde	0.007	0.993	0.000
Y47.2 Chloral derivatives	0.007	0.993	0.000
Y47.0 Barbiturates, not elsewhere classified	0.007	0.993	0.000
Y57.5 X-ray contrast media	0.007	0.993	0.000
Y59.0 Viral vaccines	0.007	0.993	0.000
Y44.5 Thrombolytic drugs	0.007	0.993	0.000
Y46.2 Hydantoin derivatives	0.007	0.993	0.000
Y49.5 Other antipsychotics and neuroleptics	0.007	0.993	0.000
Y53.4 Other laxatives	0.006	0.993	0.000
Y57.7 Vitamins, not elsewhere classified	0.007	0.993	0.000
Y57.4 Pharmaceutical excipients	0.007	0.993	0.000
Y57.3 Alcohol deterrents	0.007	0.993	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
Y57.1 Lipotropic drugs	0.007	0.993	0.000
Y57.0 Appetite depressants [anorectics]	0.007	0.993	0.000
D39.1 Ovary	0.000	0.993	0.007
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.993	0.000
Y54.0 Mineralocorticoids	0.006	0.993	0.000
Y46.4 Iminostilbenes	0.006	0.993	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.993	0.000
Z98.1 Arthrodesis status	0.007	0.993	0.000
Y55.0 Oxytocic drugs	0.006	0.993	0.000
Y47.1 Benzodiazepines	0.006	0.993	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
Y55.5 Anticommon cold drugs	0.006	0.994	0.000
Y55.3 Antitussives	0.006	0.994	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
Y53.7 Emetics	0.006	0.994	0.000
Y53.5 Digestants	0.006	0.994	0.000
Y53.0 Histamine H2-receptor antagonists	0.006	0.994	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
Y54.4 Loop [high-ceiling] diuretics	0.006	0.994	0.000
Y53.6 Antidiarrhoeal drugs	0.006	0.994	0.000
Y53.3 Saline and osmotic laxatives	0.006	0.994	0.000
Y42.1 Thyroid hormones and substitutes	0.006	0.994	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
Y54.9 Mineral salts, not elsewhere classified	0.006	0.994	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.006	0.994	0.000
Y55.4 Expectorants	0.006	0.994	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
Y49.9 Psychotropic drug, unspecified	0.006	0.994	0.000
Y49.7 Psychostimulants with abuse potential	0.006	0.994	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.006	0.994	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
Y42.4 Oral contraceptives	0.006	0.994	0.000
H57.1 Ocular pain	0.006	0.994	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.006	0.994	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
Y54.8 Agents affecting uric acid metabolism	0.006	0.994	0.000
T18.1 Foreign body in oesophagus	0.006	0.994	0.000
Y42.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
Y56.3 Emollients, demulcents and protectants	0.006	0.994	0.000
Y54.7 Agents affecting calcification	0.006	0.994	0.000
Y56.9 Topical agent, unspecified	0.006	0.994	0.000
Y56.8 Other topical agents	0.006	0.994	0.000
Y56.7 Dental drugs, topically applied	0.006	0.994	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
Y56.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
Y56.2 Local astringents and local detergents	0.006	0.994	0.000
Y56.1 Antipruritics	0.006	0.994	0.000
Y57.6 Other diagnostic agents	0.006	0.994	0.000
H55-H59 Other disorders of eye and adnexa	0.006	0.994	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.005	0.994	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.006	0.994	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.994	0.000
Y57.9 Drug or medicament, unspecified	0.006	0.994	0.000
Y52.1 Calcium-channel blockers	0.006	0.994	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.994	0.000
Y52.7 Peripheral vasodilators	0.005	0.994	0.000
H43.8 Other disorders of vitreous body	0.005	0.995	0.000
D45 Polycythaemia vera	0.000	0.995	0.005
Y49.2 Other and unspecified antidepressants	0.005	0.995	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
N20.9 Urinary calculus, unspecified	0.005	0.995	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
I67.1 Cerebral aneurysm, nonruptured	0.005	0.995	0.000
M85.6 Other cyst of bone	0.005	0.995	0.000
H55 Nystagmus and other irregular eye movements	0.005	0.995	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.004	0.995	0.000
Y84.8 Other medical procedures	0.005	0.995	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.996	0.004
G30.9 Alzheimer's disease, unspecified	0.000	0.996	0.004
M85 Other disorders of bone density and structure	0.004	0.996	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.004	0.996	0.000
H59.0 Vitreous syndrome following cataract surgery	0.004	0.996	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.004	0.996	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
F43.1 Posttraumatic stress disorder	0.000	0.996	0.004
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.004	0.996	0.000
H05.2 Exophthalmic conditions	0.004	0.996	0.000
H57.0 Anomalies of pupillary function	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.004	0.996	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.996	0.002
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000
I42 Cardiomyopathy	0.004	0.996	0.000
M85.0 Fibrous dysplasia (monostotic)	0.004	0.996	0.000
M85.64 Other cyst of bone (Hand)	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.996	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.004	0.996	0.000
M85.68 Other cyst of bone (Other)	0.004	0.996	0.000
I42.8 Other cardiomyopathies	0.004	0.996	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.004	0.996	0.000
M85.69 Other cyst of bone (Site unspecified)	0.003	0.996	0.000
M85.66 Other cyst of bone (Lower leg)	0.003	0.996	0.000
M85.63 Other cyst of bone (Forearm)	0.003	0.996	0.000
M85.62 Other cyst of bone (Upper arm)	0.003	0.996	0.000
M85.61 Other cyst of bone (Shoulder region)	0.003	0.996	0.000
M85.60 Other cyst of bone (Multiple sites)	0.003	0.996	0.000
M85.4 Solitary bone cyst	0.004	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
I69 Sequelae of cerebrovascular disease	0.004	0.996	0.000
T18 Foreign body in alimentary tract	0.004	0.996	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
N85.2 Hypertrophy of uterus	0.003	0.997	0.000
H05 Disorders of orbit	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.997	0.003
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.003	0.997	0.000
H43.9 Disorder of vitreous body, unspecified	0.003	0.997	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
M79.62 Pain in limb (Upper arm)	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.003	0.997	0.000
C44.7 Skin of lower limb, including hip	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.003	0.997	0.000
I63 Cerebral infarction	0.003	0.997	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.003	0.997	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.003	0.997	0.000
I67 Other cerebrovascular diseases	0.003	0.997	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.003	0.997	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.003	0.997	0.000
T18.2 Foreign body in stomach	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
H43 Disorders of vitreous body	0.003	0.997	0.000
H50.9 Strabismus, unspecified	0.000	0.997	0.003
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.997	0.000
S80.9 Superficial injury of lower leg, unspecified	0.003	0.997	0.000
I42.4 Endocardial fibroelastosis	0.003	0.997	0.000
T18.3 Foreign body in small intestine	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.997	0.003
J86.9 Pyothorax without fistula	0.003	0.997	0.000
W19.2 School, other institution and public administrative area	0.000	0.997	0.003
L82 Seborrhoeic keratosis	0.003	0.997	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.003	0.997	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.003	0.997	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.003	0.997	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.003	0.997	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.003	0.997	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.003	0.997	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.003	0.997	0.000
H05.3 Deformity of orbit	0.003	0.997	0.000
N20 Calculus of kidney and ureter	0.003	0.997	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.003	0.997	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.003	0.997	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.003	0.997	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.003	0.997	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.003	0.997	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.003	0.997	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.003	0.997	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.003	0.997	0.000
B02.2 Zoster with other nervous system involvement	0.003	0.997	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.46 Solitary bone cyst (Lower leg)	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
T18.5 Foreign body in anus and rectum	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
N20.0 Calculus of kidney	0.003	0.997	0.000
T18.0 Foreign body in mouth	0.003	0.997	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.003	0.997	0.000
M85.48 Solitary bone cyst (Other)	0.003	0.997	0.000
M85.44 Solitary bone cyst (Hand)	0.003	0.997	0.000
M85.43 Solitary bone cyst (Forearm)	0.003	0.997	0.000
M85.42 Solitary bone cyst (Upper arm)	0.003	0.997	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.003	0.997	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.003	0.997	0.000
I69.3 Sequelae of cerebral infarction	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.003	0.997	0.000
T18.4 Foreign body in colon	0.003	0.997	0.000
G30 Alzheimer's disease	0.000	0.997	0.003
H05.1 Chronic inflammatory disorders of orbit	0.003	0.997	0.000
H05.9 Disorder of orbit, unspecified	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
W10.4 Street and highway	0.000	0.997	0.003
I60-I69 Cerebrovascular diseases	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.997	0.000
H05.8 Other disorders of orbit	0.003	0.997	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.003	0.997	0.000
M85.18 Skeletal fluorosis (Other)	0.003	0.997	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.003	0.997	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.003	0.997	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.003	0.997	0.000
M85.14 Skeletal fluorosis (Hand)	0.003	0.997	0.000
M85.13 Skeletal fluorosis (Forearm)	0.003	0.997	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.003	0.997	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.003	0.997	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.003	0.997	0.000
M85.22 Hyperostosis of skull-Upper arm	0.003	0.997	0.000
M85.39 Osteitis condensans (Site unspecified)	0.003	0.997	0.000
M85.38 Osteitis condensans (Other)	0.003	0.997	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.003	0.997	0.000
M85.36 Osteitis condensans (Lower leg)	0.003	0.997	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.003	0.997	0.000
M85.34 Osteitis condensans (Hand)	0.003	0.997	0.000
M85.33 Osteitis condensans (Forearm)	0.003	0.997	0.000
M85.32 Osteitis condensans (Upper arm)	0.003	0.997	0.000
M85.31 Osteitis condensans (Shoulder region)	0.003	0.997	0.000
M85.30 Osteitis condensans (Multiple sites)	0.003	0.997	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.003	0.997	0.000
M85.58 Aneurysmal bone cyst (Other)	0.003	0.997	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.003	0.997	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.003	0.997	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.003	0.997	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.003	0.997	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.003	0.997	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.003	0.997	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.002	0.997	0.000
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.003	0.997	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.003	0.997	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.003	0.997	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.003	0.997	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.003	0.997	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.003	0.997	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.003	0.997	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.003	0.997	0.000
M85.29 Hyperostosis of skull-Site unspec	0.002	0.997	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.997	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.997	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.997	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.997	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.997	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.997	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.997	0.000
H05.4 Enophthalmos	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.002	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.997	0.003
I67.8 Other specified cerebrovascular diseases	0.003	0.997	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.003	0.997	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.003	0.997	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.003	0.997	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.997	0.003
M84.04 Malunion of fracture (Hand)	0.003	0.997	0.000
G56.2 Lesion of ulnar nerve	0.003	0.997	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.003	0.997	0.000
W10.8 Other specified place	0.000	0.997	0.003
Y40.6 Rifamycins	0.002	0.997	0.000
Y40.4 Tetracyclines	0.002	0.997	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.003	0.997	0.000
L89.2 Stage III decubitus ulcer	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.997	0.000
H43.0 Vitreous prolapse	0.003	0.997	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.997	0.000
W19.3 Sports and athletics area	0.000	0.997	0.003
M85.20 Hyperostosis of skull-Mult sites	0.002	0.997	0.000
Y40.8 Other systemic antibiotics	0.002	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.997	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
H50.0 Convergent concomitant strabismus	0.000	0.997	0.003
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.997	0.000
I67.5 Moyamoya disease	0.002	0.997	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.997	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.997	0.000
W19 Unspecified fall	0.000	0.997	0.003
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.997	0.000
G30.8 Other Alzheimer's disease	0.000	0.997	0.002
H43.2 Crystalline deposits in vitreous body	0.002	0.997	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.997	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
Z11.5 Special screening examination for other viral diseases	0.000	0.997	0.002
M81.8 Other osteoporosis	0.002	0.997	0.000
M83.8 Other adult osteomalacia	0.002	0.997	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.000	0.998	0.002
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
W10 Fall on and from stairs and steps	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.002	0.998	0.000
G56.8 Other mononeuropathies of upper limb	0.002	0.998	0.000
N18.0 End-stage renal disease	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.998	0.002
W19.9 Unspecified place	0.000	0.998	0.002
B02.3 Zoster ocular disease	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
B02 Zoster [herpes zoster]	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.002	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.002	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.002	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.002	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.002	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.002	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations