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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs922443
log Bayes Factor = 15.2262
Chromosome 19   position 13,158,643  (GRCh37) Explore rs922443 on Ensembl!
Variant rs922443 is part of Cluster X0293

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
N81 Female genital prolapse
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
N92 Excessive, frequent and irregular menstruation
0.991 0.009 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.989 0.011 0.000
M79.8 Other specified soft tissue disorders
0.986 0.014 0.000
Chapter XI Diseases of the digestive system
0.982 0.018 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.980 0.020 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
Chapter I Certain infectious and parasitic diseases
0.978 0.022 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.977 0.023 0.000
N30-N39 Other diseases of urinary system
0.968 0.032 0.000
N81.1 Cystocele
0.966 0.034 0.000
E11 Non-insulin-dependent diabetes mellitus
0.958 0.042 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.956 0.044 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.955 0.045 0.000
R50-R69 General symptoms and signs
0.945 0.055 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.945 0.055 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.943 0.057 0.000
H25-H28 Disorders of lens
0.940 0.060 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.934 0.066 0.000
N81.2 Incomplete uterovaginal prolapse
0.933 0.067 0.000
K90-K93 Other diseases of the digestive system
0.932 0.068 0.000
R47-R49 Symptoms and signs involving speech and voice
0.932 0.068 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.925 0.075 0.000
K50-K52 Noninfective enteritis and colitis
0.921 0.079 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.920 0.080 0.000
Chapter V Mental and behavioural disorders
0.916 0.084 0.000
N83.2 Other and unspecified ovarian cysts
0.915 0.085 0.000
K40-K46 Hernia
0.914 0.086 0.000
Chapter VI Diseases of the nervous system
0.912 0.088 0.000
N81.6 Rectocele
0.909 0.091 0.000
B95-B98 Bacterial, viral and other infectious agents
0.908 0.092 0.000
H53-H54 Visual disturbances and blindness
0.907 0.093 0.000
S20-S29 Injuries to the thorax
0.903 0.097 0.000
R30-R39 Symptoms and signs involving the urinary system
0.903 0.097 0.000
M80-M85 Disorders of bone density and structure
0.901 0.099 0.000
R47 Speech disturbances, not elsewhere classified
0.899 0.101 0.000
E11.9 Without complications
0.895 0.105 0.000
H30-H36 Disorders of choroid and retina
0.892 0.108 0.000
N32 Other disorders of bladder
0.891 0.109 0.000
L03 Cellulitis
0.890 0.110 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.890 0.110 0.000
K92 Other diseases of digestive system
0.889 0.111 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.889 0.111 0.000
H26 Other cataract
0.887 0.113 0.000
E50-E64 Other nutritional deficiencies
0.887 0.113 0.000
M50-M54 Other dorsopathies
0.884 0.116 0.000
N39 Other disorders of urinary system
0.880 0.120 0.000
L82 Seborrhoeic keratosis
0.873 0.127 0.000
R31 Unspecified haematuria
0.873 0.127 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.866 0.134 0.000
R59 Enlarged lymph nodes
0.865 0.135 0.000
B35-B49 Mycoses
0.865 0.135 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.864 0.136 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.862 0.138 0.000
K55-K64 Other diseases of intestines
0.859 0.141 0.000
K40 Inguinal hernia
0.859 0.141 0.000
R63 Symptoms and signs concerning food and fluid intake
0.857 0.143 0.000
Z04 Examination and observation for other reasons
0.854 0.146 0.000
Z12 Special screening examination for neoplasms
0.853 0.147 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.850 0.149 0.000
Z53.0 Procedure not carried out because of contraindication
0.847 0.153 0.000
A00-A09 Intestinal infectious diseases
0.847 0.153 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.846 0.153 0.000
K52 Other non-infective gastro-enteritis and colitis
0.846 0.154 0.000
S80-S89 Injuries to the knee and lower leg
0.845 0.155 0.000
M79.5 Residual foreign body in soft tissue
0.843 0.157 0.000
R26 Abnormalities of gait and mobility
0.843 0.157 0.000
H53 Visual disturbances
0.835 0.165 0.000
R47.0 Dysphasia and aphasia
0.834 0.166 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.834 0.166 0.000
E11.3 With ophthalmic complications
0.831 0.169 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.830 0.170 0.000
H43-H45 Disorders of vitreous body and globe
0.828 0.172 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.827 0.173 0.000
N81.8 Other female genital prolapse
0.825 0.175 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.824 0.176 0.000
R25 Abnormal involuntary movements
0.824 0.176 0.000
L91 Hypertrophic disorders of skin
0.824 0.176 0.000
K57 Diverticular disease of intestine
0.821 0.179 0.000
Chapter XX External causes of morbidity and mortality
0.821 0.179 0.000
R59.9 Enlarged lymph nodes, unspecified
0.820 0.180 0.000
S60-S69 Injuries to the wrist and hand
0.819 0.181 0.000
N81.5 Vaginal enterocele
0.819 0.181 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.818 0.182 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.814 0.186 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.812 0.188 0.000
E53 Deficiency of other B group vitamins
0.808 0.192 0.000
M51 Other intervertebral disk disorders
0.807 0.193 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.805 0.195 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.804 0.196 0.000
K92.1 Melaena
0.803 0.197 0.000
M79.6 Pain in limb
0.803 0.197 0.000
D70 Agranulocytosis
0.802 0.198 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.801 0.199 0.000
E65-E68 Obesity and other hyperalimentation
0.800 0.200 0.000
E00-E07 Disorders of thyroid gland
0.800 0.200 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.798 0.202 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.795 0.205 0.000
R69 Unknown and unspecified causes of morbidity
0.794 0.206 0.000
Z04.9 Examination and observation for unspecified reason
0.794 0.206 0.000
L03.3 Cellulitis of trunk
0.793 0.207 0.000
N39.3 Stress incontinence
0.792 0.208 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.792 0.208 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.792 0.208 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.791 0.209 0.000
T66-T78 Other and unspecified effects of external causes
0.791 0.209 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.790 0.210 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.786 0.214 0.000
M81 Osteoporosis without pathological fracture
0.785 0.215 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.784 0.215 0.000
N89 Other noninflammatory disorders of vagina
0.784 0.216 0.000
B37 Candidiasis
0.783 0.217 0.000
L20-L30 Dermatitis and eczema
0.783 0.217 0.000
M05-M14 Inflammatory polyarthropathies
0.780 0.220 0.000
E14 Unspecified diabetes mellitus
0.779 0.221 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.779 0.221 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.779 0.221 0.000
L05 Pilonidal cyst
0.778 0.222 0.000
N81.3 Complete uterovaginal prolapse
0.776 0.224 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.775 0.225 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.775 0.225 0.000
R53 Malaise and fatigue
0.774 0.226 0.000
E20-E35 Disorders of other endocrine glands
0.773 0.227 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.773 0.227 0.000
N32.3 Diverticulum of bladder
0.770 0.230 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.768 0.232 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.768 0.232 0.000
H26.4 After-cataract
0.766 0.234 0.000
L50-L54 Urticaria and erythema
0.763 0.237 0.000
K50 Crohn's disease [regional enteritis]
0.763 0.237 0.000
E11.4 With neurological complications
0.762 0.238 0.000
H55-H59 Other disorders of eye and adnexa
0.761 0.239 0.000
H35 Other retinal disorders
0.761 0.239 0.000
M79.0 Rheumatism, unspecified
0.761 0.239 0.000
L03.1 Cellulitis of other parts of limb
0.761 0.239 0.000
N75 Diseases of Bartholin's gland
0.759 0.241 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.758 0.242 0.000
S40-S49 Injuries to the shoulder and upper arm
0.757 0.242 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.755 0.245 0.000
N25-N29 Other disorders of kidney and ureter
0.755 0.245 0.000
N30 Cystitis
0.754 0.246 0.000
G90-G99 Other disorders of the nervous system
0.753 0.247 0.000
R47.8 Other and unspecified speech disturbances
0.753 0.247 0.000
M65-M68 Disorders of synovium and tendon
0.753 0.247 0.000
R68 Other general symptoms and signs
0.752 0.248 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.751 0.248 0.000
F30-F39 Mood [affective] disorders
0.752 0.248 0.000
E53.8 Deficiency of other specified B group vitamins
0.751 0.249 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.751 0.249 0.000
E10 Insulin-dependent diabetes mellitus
0.750 0.250 0.000
A30-A49 Other bacterial diseases
0.750 0.250 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.749 0.251 0.000
Z46 Fitting and adjustment of other devices
0.749 0.251 0.000
M45-M49 Spondylopathies
0.748 0.252 0.000
E16 Other disorders of pancreatic internal secretion
0.746 0.254 0.000
E11.2 With renal complications
0.746 0.254 0.000
R50 Fever of unknown origin
0.746 0.254 0.000
N60-N64 Disorders of breast
0.745 0.255 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
N32.0 Bladder-neck obstruction
0.744 0.256 0.000
N10-N16 Renal tubulo-interstitial diseases
0.743 0.256 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.742 0.258 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.742 0.258 0.000
M75 Shoulder lesions
0.740 0.260 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
H25 Senile cataract
0.739 0.261 0.000
R47.1 Dysarthria and anarthria
0.737 0.263 0.000
A04 Other bacterial intestinal infections
0.736 0.263 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.736 0.264 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
R63.4 Abnormal weight loss
0.735 0.265 0.000
N86 Erosion and ectropion of cervix uteri
0.734 0.266 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.733 0.267 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.732 0.268 0.000
T42.4 Benzodiazepines
0.732 0.268 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.731 0.268 0.000
L40-L45 Papulosquamous disorders
0.731 0.269 0.000
K45 Other abdominal hernia
0.730 0.270 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.730 0.270 0.000
N39.4 Other specified urinary incontinence
0.730 0.270 0.000
M84 Disorders of continuity of bone
0.730 0.270 0.000
Z49 Care involving dialysis
0.729 0.271 0.000
L81 Other disorders of pigmentation
0.728 0.272 0.000
S27 Injury of other and unspecified intrathoracic organs
0.728 0.272 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.727 0.273 0.000
F41 Other anxiety disorders
0.725 0.275 0.000
Z42 Follow-up care involving plastic surgery
0.723 0.277 0.000
H26.1 Traumatic cataract
0.722 0.278 0.000
N92.4 Excessive bleeding in the premenopausal period
0.720 0.280 0.000
N99-N99 Other disorders of the genitourinary system
0.719 0.280 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.719 0.281 0.000
N81.4 Uterovaginal prolapse, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K60 Fissure and fistula of anal and rectal regions
0.717 0.283 0.000
G81 Hemiplegia
0.717 0.283 0.000
H26.2 Complicated cataract
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.716 0.283 0.000
N91 Absent, scanty and rare menstruation
0.716 0.283 0.000
N82 Fistulae involving female genital tract
0.716 0.283 0.000
N96 Habitual aborter
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
N81.9 Female genital prolapse, unspecified
0.716 0.284 0.000
N81.0 Female urethrocele
0.716 0.284 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.715 0.285 0.000
R80 Isolated proteinuria
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
H10-H13 Disorders of conjunctiva
0.714 0.286 0.000
G20-G26 Extrapyramidal and movement disorders
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
N73 Other female pelvic inflammatory diseases
0.713 0.286 0.000
E11.5 With peripheral circulatory complications
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.287 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.287 0.000
M71 Other bursopathies
0.713 0.287 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.713 0.287 0.000
R54 Senility
0.712 0.288 0.000
R63.0 Anorexia
0.712 0.288 0.000
M79.9 Soft tissue disorder, unspecified
0.711 0.288 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.711 0.288 0.000
M79.3 Panniculitis, unspecified
0.711 0.288 0.000
M79.2 Neuralgia and neuritis, unspecified
0.711 0.288 0.000
M79.1 Myalgia
0.711 0.288 0.000
T79-T79 Certain early complications of trauma
0.711 0.289 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
S90-S99 Injuries to the ankle and foot
0.711 0.289 0.000
S10-S19 Injuries to the neck
0.711 0.289 0.000
N70 Salpingitis and oophoritis
0.711 0.289 0.000
N92.5 Other specified irregular menstruation
0.710 0.289 0.000
N92.2 Excessive menstruation at puberty
0.710 0.289 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.710 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
Chapter XXII Codes for special purposes
0.710 0.290 0.000
Z45 Adjustment and management of implanted device
0.710 0.290 0.000
N88 Other noninflammatory disorders of cervix uteri
0.709 0.290 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
H53.0 Amblyopia ex anopsia
0.709 0.291 0.000
M79.7 Fibromyalgia
0.709 0.291 0.000
N83.1 Corpus luteum cyst
0.708 0.292 0.000
R33 Retention of urine
0.708 0.292 0.000
N36 Other disorders of urethra
0.708 0.292 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
S22.4 Multiple fractures of ribs
0.707 0.293 0.000
M79.88 Other specified soft tissue disorders (Other)
0.707 0.293 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.707 0.293 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.707 0.293 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.707 0.293 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.707 0.293 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.707 0.293 0.000
Z52 Donors of organs and tissues
0.706 0.294 0.000
H33 Retinal detachments and breaks
0.705 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
K65-K67 Diseases of peritoneum
0.703 0.297 0.000
E13 Other specified diabetes mellitus
0.702 0.298 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
M81.9 Osteoporosis, unspecified
0.701 0.299 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.700 0.299 0.000
Z43 Attention to artificial openings
0.699 0.301 0.000
K44 Diaphragmatic hernia
0.699 0.301 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.699 0.301 0.000
H36 Retinal disorders in diseases classified elsewhere
0.698 0.302 0.000
Z50 Care involving use of rehabilitation procedures
0.698 0.302 0.000
L60-L75 Disorders of skin appendages
0.698 0.302 0.000
M77 Other enthesopathies
0.697 0.302 0.000
Z00.0 General medical examination
0.696 0.304 0.000
O60-O75 Complications of labour and delivery
0.696 0.304 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
H40-H42 Glaucoma
0.696 0.304 0.000
N00-N08 Glomerular diseases
0.696 0.304 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.695 0.305 0.000
L91.0 Keloid scar
0.695 0.305 0.000
N37 Urethral disorders in diseases classified elsewhere
0.694 0.306 0.000
N34 Urethritis and urethral syndrome
0.694 0.306 0.000
N33 Bladder disorders in diseases classified elsewhere
0.694 0.306 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.692 0.308 0.000
M40-M43 Deforming dorsopathies
0.692 0.308 0.000
H53.9 Visual disturbance, unspecified
0.692 0.308 0.000
N20-N23 Urolithiasis
0.692 0.308 0.000
K55 Vascular disorders of intestine
0.691 0.309 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.690 0.310 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.687 0.313 0.000
E11.8 With unspecified complications
0.687 0.313 0.000
E11.7 With multiple complications
0.687 0.313 0.000
E11.6 With other specified complications
0.687 0.313 0.000
E11.1 With ketoacidosis
0.687 0.313 0.000
E11.0 With coma
0.687 0.313 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.687 0.313 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.686 0.314 0.000
Z10 Routine general health check-up of defined subpopulation
0.686 0.314 0.000
Z63 Other problems related to primary support group, including family circumstances
0.686 0.314 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.685 0.314 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.685 0.315 0.000
N83.7 Haematoma of broad ligament
0.685 0.315 0.000
N83.6 Haematosalpinx
0.685 0.315 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.685 0.315 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.685 0.315 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.685 0.315 0.000
K46 Unspecified abdominal hernia
0.684 0.316 0.000
M51.9 Intervertebral disk disorder, unspecified
0.684 0.316 0.000
R60 Oedema, not elsewhere classified
0.684 0.316 0.000
Z41 Procedures for purposes other than remedying health state
0.683 0.317 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.682 0.318 0.000
H26.8 Other specified cataract
0.681 0.319 0.000
O00-O08 Pregnancy with abortive outcome
0.681 0.319 0.000
M53 Other dorsopathies, not elsewhere classified
0.681 0.319 0.000
N39.0 Urinary tract infection, site not specified
0.681 0.319 0.000
H54 Blindness and low vision
0.680 0.320 0.000
Z29 Need for other prophylactic measures
0.680 0.320 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.680 0.320 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.679 0.321 0.000
L91.8 Other hypertrophic disorders of skin
0.679 0.321 0.000
H44 Disorders of globe
0.679 0.321 0.000
L03.2 Cellulitis of face
0.679 0.321 0.000
K61 Abscess of anal and rectal regions
0.678 0.322 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.678 0.322 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.678 0.322 0.000
R62 Lack of expected normal physiological development
0.678 0.322 0.000
R57 Shock, not elsewhere classified
0.678 0.322 0.000
R64 Cachexia
0.678 0.322 0.000
R58 Haemorrhage, not elsewhere classified
0.678 0.322 0.000
N71 Inflammatory disease of uterus, except cervix
0.677 0.323 0.000
R27 Other lack of coordination
0.677 0.323 0.000
K92.0 Haematemesis
0.677 0.323 0.000
N92.3 Ovulation bleeding
0.676 0.324 0.000
L04 Acute lymphadenitis
0.676 0.324 0.000
L01 Impetigo
0.676 0.324 0.000
L00 Staphylococcal scalded skin syndrome
0.676 0.324 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.674 0.326 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.674 0.326 0.000
H27 Other disorders of lens
0.674 0.326 0.000
M80 Osteoporosis with pathological fracture
0.674 0.326 0.000
K91.3 Postoperative intestinal obstruction
0.674 0.326 0.000
H26.9 Cataract, unspecified
0.674 0.326 0.000
N32.8 Other specified disorders of bladder
0.674 0.326 0.000
K51 Ulcerative colitis
0.673 0.327 0.000
S20 Superficial injury of thorax
0.673 0.327 0.000
M51.8 Other specified intervertebral disk disorders
0.672 0.328 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.672 0.328 0.000
M79.66 Pain in limb (Lower leg)
0.672 0.328 0.000
D80-D89 Certain disorders involving the immune mechanism
0.672 0.328 0.000
E16.2 Hypoglycaemia, unspecified
0.672 0.328 0.000
N75.0 Cyst of Bartholin's gland
0.671 0.329 0.000
S00-S09 Injuries to the head
0.670 0.330 0.000
R61 Hyperhidrosis
0.670 0.330 0.000
N30.2 Other chronic cystitis
0.670 0.330 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.670 0.330 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.670 0.330 0.000
L94 Other localised connective tissue disorders
0.670 0.330 0.000
L93 Lupus erythematosus
0.670 0.330 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.670 0.330 0.000
L89 Decubitus ulcer
0.670 0.330 0.000
L87 Transepidermal elimination disorders
0.670 0.330 0.000
L88 Pyoderma gangrenosum
0.670 0.330 0.000
L86 Keratoderma in diseases classified elsewhere
0.670 0.330 0.000
L84 Corns and callosities
0.670 0.330 0.000
L83 Acanthosis nigricans
0.670 0.330 0.000
L80 Vitiligo
0.670 0.330 0.000
L08 Other local infections of skin and subcutaneous tissue
0.670 0.330 0.000
B37.8 Candidiasis of other sites
0.669 0.331 0.000
S89 Other and unspecified injuries of lower leg
0.669 0.331 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.668 0.331 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.668 0.332 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.667 0.333 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.667 0.333 0.000
L85 Other epidermal thickening
0.667 0.333 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.666 0.334 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.666 0.334 0.000
F41.2 Mixed anxiety and depressive disorder
0.665 0.335 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.665 0.335 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.664 0.335 0.000
L03.9 Cellulitis, unspecified
0.663 0.337 0.000
Z54 Convalescence
0.663 0.337 0.000
Z44 Fitting and adjustment of external prosthetic device
0.663 0.337 0.000
N32.9 Bladder disorder, unspecified
0.662 0.338 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
R29.6 Tendency to fall, not elsewhere classified
0.661 0.339 0.000
E66 Obesity
0.660 0.339 0.000
K35-K38 Diseases of appendix
0.660 0.340 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.660 0.340 0.000
M79.67 Pain in limb (Ankle and foot)
0.659 0.341 0.000
K60.2 Anal fissure, unspecified
0.659 0.341 0.000
G81.9 Hemiplegia, unspecified
0.658 0.341 0.000
O80-O84 Delivery
0.658 0.342 0.000
B37.0 Candidal stomatitis
0.658 0.342 0.000
E04 Other non-toxic goitre
0.657 0.343 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.657 0.343 0.000
F99-F99 Unspecified mental disorder
0.656 0.343 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.656 0.343 0.000
F80-F89 Disorders of psychological development
0.656 0.343 0.000
F70-F79 Mental retardation
0.656 0.343 0.000
F60-F69 Disorders of adult personality and behaviour
0.656 0.343 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.656 0.343 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.656 0.343 0.000
E61 Deficiency of other nutrient elements
0.656 0.344 0.000
K92.9 Disease of digestive system, unspecified
0.655 0.345 0.000
M72 Fibroblastic disorders
0.654 0.346 0.000
G70-G73 Diseases of myoneural junction and muscle
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.654 0.346 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.654 0.346 0.000
R25.1 Tremor, unspecified
0.653 0.346 0.000
G57 Mononeuropathies of lower limb
0.653 0.347 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.652 0.348 0.000
K41 Femoral hernia
0.652 0.348 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.652 0.348 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.649 0.351 0.000
D75 Other diseases of blood and blood-forming organs
0.649 0.351 0.000
M15-M19 Arthrosis
0.648 0.352 0.000
A08 Viral and other specified intestinal infections
0.648 0.352 0.000
S29 Other and unspecified injuries of thorax
0.648 0.352 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.648 0.352 0.000
S26 Injury of heart
0.648 0.352 0.000
S25 Injury of blood vessels of thorax
0.648 0.352 0.000
S24 Injury of nerves and spinal cord at thorax level
0.648 0.352 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.648 0.352 0.000
S21 Open wound of thorax
0.648 0.352 0.000
T78 Adverse effects, not elsewhere classified
0.648 0.352 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.648 0.352 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.647 0.353 0.000
R36 Urethral discharge
0.647 0.353 0.000
R34 Anuria and oliguria
0.647 0.353 0.000
N35 Urethral stricture
0.646 0.353 0.000
M85 Other disorders of bone density and structure
0.646 0.354 0.000
M83 Adult osteomalacia
0.646 0.354 0.000
M82 Osteoporosis in diseases classified elsewhere
0.646 0.354 0.000
H25.9 Senile cataract, unspecified
0.646 0.354 0.000
R30 Pain associated with micturition
0.646 0.354 0.000
L05.9 Pilonidal cyst without abscess
0.645 0.355 0.000
S81 Open wound of lower leg
0.644 0.356 0.000
D73 Diseases of spleen
0.644 0.356 0.000
M13 Other arthritis
0.640 0.360 0.000
S22.40 Multiple fractures of ribs (closed)
0.640 0.360 0.000
H34 Retinal vascular occlusions
0.640 0.360 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.640 0.360 0.000
H31 Other disorders of choroid
0.640 0.360 0.000
H30 Chorioretinal inflammation
0.640 0.360 0.000
N32.4 Rupture of bladder, nontraumatic
0.639 0.361 0.000
N32.2 Vesical fistula, not elsewhere classified
0.639 0.361 0.000
N32.1 Vesicointestinal fistula
0.639 0.361 0.000
H43 Disorders of vitreous body
0.639 0.361 0.000
S80 Superficial injury of lower leg
0.638 0.361 0.000
L03.8 Cellulitis of other sites
0.638 0.362 0.000
D55-D59 Haemolytic anaemias
0.638 0.362 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.638 0.362 0.000
H18 Other disorders of cornea
0.637 0.362 0.000
K92.8 Other specified diseases of digestive system
0.637 0.363 0.000
N76 Other inflammation of vagina and vulva
0.637 0.363 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.637 0.363 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.637 0.363 0.000
Q60-Q64 Congenital malformations of the urinary system
0.637 0.363 0.000
L03.0 Cellulitis of finger and toe
0.637 0.363 0.000
A04.5 Campylobacter enteritis
0.636 0.363 0.000
H26.3 Drug-induced cataract
0.636 0.364 0.000
H26.0 Infantile, juvenile and presenile cataract
0.636 0.364 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.636 0.364 0.000
E63 Other nutritional deficiencies
0.636 0.364 0.000
E56 Other vitamin deficiencies
0.636 0.364 0.000
E51 Thiamine deficiency
0.636 0.364 0.000
E50 Vitamin A deficiency
0.636 0.364 0.000
E60 Dietary zinc deficiency
0.636 0.364 0.000
E59 Dietary selenium deficiency
0.636 0.364 0.000
E58 Dietary calcium deficiency
0.636 0.364 0.000
E54 Ascorbic acid deficiency
0.636 0.364 0.000
E52 Niacin deficiency [pellagra]
0.636 0.364 0.000
Z03.1 Observation for suspected malignant neoplasm
0.636 0.364 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.635 0.364 0.000
H53.1 Subjective visual disturbances
0.635 0.364 0.000
M51.2 Other specified intervertebral disk displacement
0.635 0.365 0.000
K43 Ventral hernia
0.635 0.365 0.000
N83.0 Follicular cyst of ovary
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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