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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9267972
log Bayes Factor = 173.996
Chromosome 6   position 32,217,232  (GRCh37) Explore rs9267972 on Ensembl!
Variant rs9267972 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
M05 Seropositive rheumatoid arthritis
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.997 0.003 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.995 0.005 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.985 0.015 0.000
M06.3 Rheumatoid nodule
0.975 0.025 0.000
E00-E07 Disorders of thyroid gland
0.000 0.025 0.975
M45.X9 Ankylosing spondylitis (Site unspecified)
0.960 0.040 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.045 0.955
E27 Other disorders of adrenal gland
0.000 0.049 0.951
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.057 0.943
M06.0 Seronegative rheumatoid arthritis
0.940 0.060 0.000
E04 Other non-toxic goitre
0.000 0.060 0.940
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.938 0.062 0.000
M06.34 Rheumatoid nodule (Hand)
0.930 0.070 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.082 0.918
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.082 0.918
B37.8 Candidiasis of other sites
0.000 0.085 0.915
G37 Other demyelinating diseases of central nervous system
0.000 0.086 0.914
M06.4 Inflammatory polyarthropathy
0.909 0.091 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.095 0.905
E27.2 Addisonian crisis
0.000 0.105 0.895
K90 Intestinal malabsorption
0.000 0.107 0.893
E04.2 Non-toxic multinodular goitre
0.000 0.108 0.892
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.875 0.124 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.862 0.138 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.139 0.861
E27.8 Other specified disorders of adrenal gland
0.000 0.144 0.856
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.853 0.147 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.845 0.155 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.160 0.840
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.838 0.162 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.834 0.166 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.831 0.169 0.000
M05.1 Rheumatoid lung disease
0.825 0.175 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.818 0.182 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.814 0.186 0.000
E50-E64 Other nutritional deficiencies
0.000 0.195 0.805
M45 Ankylosing spondylitis
0.802 0.198 0.000
M05.8 Other seropositive rheumatoid arthritis
0.799 0.201 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.799 0.201 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.796 0.204 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.795 0.205 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.790 0.210 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.217 0.783
M06.32 Rheumatoid nodule (Upper arm)
0.781 0.219 0.000
M08 Juvenile arthritis
0.776 0.224 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.226 0.774
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.771 0.229 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.770 0.230 0.000
E07 Other disorders of thyroid
0.000 0.245 0.755
M05.2 Rheumatoid vasculitis
0.755 0.245 0.000
M06.1 Adult-onset Still's disease
0.754 0.246 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.255 0.745
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.743 0.257 0.000
M06.33 Rheumatoid nodule (Forearm)
0.743 0.257 0.000
E31 Polyglandular dysfunction
0.000 0.262 0.738
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.733 0.267 0.000
E55 Vitamin D deficiency
0.000 0.268 0.732
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.727 0.273 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.273 0.727
M06.30 Rheumatoid nodule (Multiple sites)
0.725 0.275 0.000
E20 Hypoparathyroidism
0.000 0.275 0.725
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.275 0.725
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
B37 Candidiasis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.716 0.284 0.000
M05.0 Felty's syndrome
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.710 0.290 0.000
M06.8 Other specified rheumatoid arthritis
0.709 0.291 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.708 0.292 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.705 0.295 0.000
K90.8 Other intestinal malabsorption
0.000 0.296 0.704
M06.39 Rheumatoid nodule (Site unspecified)
0.699 0.301 0.000
M06.38 Rheumatoid nodule (Other)
0.699 0.301 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.699 0.301 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.699 0.301 0.000
E07.8 Other specified disorders of thyroid
0.000 0.301 0.699
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.301 0.699
E00 Congenital iodine-deficiency syndrome
0.000 0.301 0.699
M12 Other specific arthropathies
0.697 0.303 0.000
E34 Other endocrine disorders
0.000 0.303 0.697
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.696 0.304 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.310 0.689
E05.8 Other thyrotoxicosis
0.000 0.315 0.685
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.683 0.317 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.318 0.682
E27.0 Other adrenocortical overactivity
0.000 0.318 0.682
E55.9 Vitamin D deficiency, unspecified
0.000 0.321 0.679
E51 Thiamine deficiency
0.000 0.324 0.676
M06.04 Seronegative rheumatoid arthritis (Hand)
0.675 0.325 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.674 0.326 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.674 0.326 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.674 0.326 0.000
E04.8 Other specified non-toxic goitre
0.000 0.326 0.674
B37.9 Candidiasis, unspecified
0.000 0.327 0.673
M45.X2 Ankylosing spondylitis (Cervical region)
0.665 0.335 0.000
E22 Hyperfunction of pituitary gland
0.000 0.335 0.665
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.342 0.658
E30 Disorders of puberty, not elsewhere classified
0.000 0.342 0.658
M05.19 Rheumatoid lung disease (Site unspecified)
0.658 0.342 0.000
G36 Other acute disseminated demyelination
0.000 0.344 0.656
G37.5 Concentric sclerosis [Balo]
0.000 0.345 0.655
G37.4 Subacute necrotising myelitis
0.000 0.345 0.655
G37.2 Central pontine myelinolysis
0.000 0.345 0.655
G37.1 Central demyelination of corpus callosum
0.000 0.345 0.655
G37.0 Diffuse sclerosis
0.000 0.345 0.655
E32 Diseases of thymus
0.000 0.346 0.654
M06.48 Inflammatory polyarthropathy (Other)
0.651 0.348 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.651 0.348 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.651 0.348 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.651 0.348 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.651 0.348 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.651 0.348 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.651 0.348 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.651 0.349 0.000
M11 Other crystal arthropathies
0.645 0.355 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.359 0.641
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.359 0.641
K90.1 Tropical sprue
0.000 0.359 0.641
M14 Arthropathies in other diseases classified elsewhere
0.640 0.360 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.636 0.364 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.634 0.366 0.000
E53 Deficiency of other B group vitamins
0.000 0.376 0.624
M08.0 Juvenile rheumatoid arthritis
0.617 0.383 0.000
E40-E46 Malnutrition
0.000 0.390 0.610
E31.0 Autoimmune polyglandular failure
0.000 0.391 0.609
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.604 0.396 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.597 0.403 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.404 0.596
E34.0 Carcinoid syndrome
0.000 0.407 0.593
Chapter VI Diseases of the nervous system
0.000 0.408 0.592
M05.18 Rheumatoid lung disease (Other)
0.591 0.408 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.591 0.408 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.591 0.408 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.591 0.408 0.000
M05.14 Rheumatoid lung disease (Hand)
0.591 0.408 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.591 0.408 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.591 0.408 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.591 0.408 0.000
D50-D53 Nutritional anaemias
0.000 0.411 0.589
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.411 0.589
E20.9 Hypoparathyroidism, unspecified
0.000 0.413 0.587
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.415 0.585
D51 Vitamin B12 deficiency anaemia
0.000 0.416 0.584
E51.2 Wernicke's encephalopathy
0.000 0.417 0.583
M06.10 Adult-onset Still's disease (Multiple sites)
0.578 0.422 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.423 0.577
E63 Other nutritional deficiencies
0.000 0.423 0.577
E50 Vitamin A deficiency
0.000 0.423 0.577
E60 Dietary zinc deficiency
0.000 0.423 0.577
E59 Dietary selenium deficiency
0.000 0.423 0.577
E52 Niacin deficiency [pellagra]
0.000 0.423 0.577
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.575 0.425 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.575 0.425 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.575 0.425 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.575 0.425 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.575 0.425 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.575 0.425 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.573 0.427 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.573 0.427 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.573 0.427 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.573 0.427 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.573 0.427 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.573 0.427 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.573 0.427 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.573 0.427 0.000
D52 Folate deficiency anaemia
0.000 0.428 0.572
E28 Ovarian dysfunction
0.000 0.429 0.571
B37.1 Pulmonary candidiasis
0.000 0.431 0.569
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.432 0.568
G40-G47 Episodic and paroxysmal disorders
0.000 0.435 0.565
D52.9 Folate deficiency anaemia, unspecified
0.000 0.439 0.561
E61 Deficiency of other nutrient elements
0.000 0.439 0.561
E25 Adrenogenital disorders
0.000 0.440 0.560
M08.9 Juvenile arthritis, unspecified
0.556 0.444 0.000
M08.8 Other juvenile arthritis
0.556 0.444 0.000
M08.4 Pauciarticular juvenile arthritis
0.556 0.444 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.556 0.444 0.000
M08.2 Juvenile arthritis with systemic onset
0.556 0.444 0.000
M08.1 Juvenile ankylosing spondylitis
0.556 0.444 0.000
E24 Cushing's syndrome
0.000 0.446 0.554
B35-B49 Mycoses
0.000 0.447 0.552
G40 Epilepsy
0.000 0.448 0.552
M45.X6 Ankylosing spondylitis (Lumbar region)
0.550 0.449 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.453 0.547
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.457 0.543
Chapter I Certain infectious and parasitic diseases
0.000 0.458 0.542
E07.1 Dyshormogenetic goitre
0.000 0.459 0.541
E07.0 Hypersecretion of calcitonin
0.000 0.459 0.541
M05.28 Rheumatoid vasculitis (Other)
0.541 0.459 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.541 0.459 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.541 0.459 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.541 0.459 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.541 0.459 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.541 0.459 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.541 0.459 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.541 0.459 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.541 0.459 0.000
M06.18 Adult-onset Still's disease (Other)
0.541 0.459 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.541 0.459 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.541 0.459 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.541 0.459 0.000
M06.14 Adult-onset Still's disease (Hand)
0.541 0.459 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.541 0.459 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.541 0.459 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.541 0.459 0.000
M12.3 Palindromic rheumatism
0.538 0.462 0.000
B07 Viral warts
0.000 0.464 0.536
E21.3 Hyperparathyroidism, unspecified
0.000 0.465 0.535
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.466 0.534
B37.4 Candidiasis of other urogenital sites
0.000 0.467 0.533
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.467 0.533
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.468 0.532
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.471 0.529
E31.9 Polyglandular dysfunction, unspecified
0.000 0.471 0.529
E31.8 Other polyglandular dysfunction
0.000 0.471 0.529
E31.1 Polyglandular hyperfunction
0.000 0.471 0.529
# Top node
0.000 0.473 0.527
E22.0 Acromegaly and pituitary gigantism
0.000 0.474 0.526
E55.0 Rickets, active
0.000 0.475 0.524
E56 Other vitamin deficiencies
0.000 0.476 0.524
E20.8 Other hypoparathyroidism
0.000 0.480 0.520
E20.1 Pseudohypoparathyroidism
0.000 0.480 0.520
E20.0 Idiopathic hypoparathyroidism
0.000 0.480 0.520
M05.20 Rheumatoid vasculitis (Multiple sites)
0.518 0.482 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.483 0.517
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
B37.6 Candidal endocarditis
0.000 0.486 0.514
B37.5 Candidal meningitis
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.513 0.486 0.000
M05.08 Felty's syndrome (Other)
0.513 0.486 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.513 0.486 0.000
M05.06 Felty's syndrome (Lower leg)
0.513 0.486 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.513 0.486 0.000
M05.04 Felty's syndrome (Hand)
0.513 0.486 0.000
M05.03 Felty's syndrome (Forearm)
0.513 0.486 0.000
M05.02 Felty's syndrome (Upper arm)
0.513 0.486 0.000
M05.01 Felty's syndrome (Shoulder region)
0.513 0.486 0.000
M05.00 Felty's syndrome (Multiple sites)
0.513 0.486 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.513 0.486 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.513 0.486 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.513 0.486 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.513 0.486 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.513 0.486 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.513 0.486 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.513 0.486 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.513 0.486 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.513 0.486 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.513 0.486 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.512 0.487 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.512 0.487 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.512 0.487 0.000
M09.0 Juvenile arthritis in psoriasis
0.512 0.487 0.000
M07 Psoriatic and enteropathic arthropathies
0.512 0.488 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.489 0.511
E34.8 Other specified endocrine disorders
0.000 0.489 0.510
G20-G26 Extrapyramidal and movement disorders
0.000 0.490 0.510
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.491 0.509
M06.88 Other specified rheumatoid arthritis (Other)
0.508 0.492 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.508 0.492 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.508 0.492 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.508 0.492 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.508 0.492 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.508 0.492 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.508 0.492 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.508 0.492 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.508 0.492 0.000
D86 Sarcoidosis
0.000 0.492 0.508
E58 Dietary calcium deficiency
0.000 0.494 0.506
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.496 0.504
E53.8 Deficiency of other specified B group vitamins
0.000 0.498 0.502
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.498 0.502
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.499 0.501
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.499 0.501
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.499 0.501
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.499 0.501
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.499 0.501
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.499 0.501
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.499 0.501
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.499 0.501
M12.4 Intermittent hydrarthrosis
0.500 0.500 0.000
M12.1 Kaschin-Beck disease
0.500 0.500 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.500 0.500 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.500 0.500 0.000
E34.5 Androgen resistance syndrome
0.000 0.500 0.500
E34.4 Constitutional tall stature
0.000 0.500 0.500
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.500 0.500
E34.1 Other hypersecretion of intestinal hormones
0.000 0.500 0.500
E04.9 Non-toxic goitre, unspecified
0.000 0.501 0.499
B37.2 Candidiasis of skin and nail
0.000 0.501 0.499
M14.6 Neuropathic arthropathy
0.498 0.502 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.502 0.498
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.505 0.495
M12.5 Traumatic arthropathy
0.490 0.510 0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.489 0.511 0.000
G20 Parkinson's disease
0.000 0.512 0.488
E06 Thyroiditis
0.000 0.514 0.486
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.515 0.485
E51.9 Thiamine deficiency, unspecified
0.000 0.515 0.484
E51.8 Other manifestations of thiamine deficiency
0.000 0.515 0.484
E51.1 Beriberi
0.000 0.515 0.484
E54 Ascorbic acid deficiency
0.000 0.518 0.482
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.520 0.480
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.521 0.479
M12.2 Villonodular synovitis (pigmented)
0.478 0.522 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.523 0.476
E22.8 Other hyperfunction of pituitary gland
0.000 0.523 0.476
G40.5 Special epileptic syndromes
0.000 0.524 0.476
D55-D59 Haemolytic anaemias
0.000 0.526 0.474
E30.9 Disorder of puberty, unspecified
0.000 0.528 0.472
E30.8 Other disorders of puberty
0.000 0.528 0.472
E30.1 Precocious puberty
0.000 0.528 0.472
E30.0 Delayed puberty
0.000 0.528 0.472
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.528 0.472
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.528 0.472
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.528 0.472
A63.0 Anogenital (venereal) warts
0.000 0.529 0.471
G36.9 Acute disseminated demyelination, unspecified
0.000 0.529 0.470
G36.8 Other specified acute disseminated demyelination
0.000 0.529 0.470
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.529 0.470
M12.8 Other specific arthropathies, not elsewhere classified
0.469 0.531 0.000
E32.9 Disease of thymus, unspecified
0.000 0.531 0.469
E32.1 Abscess of thymus
0.000 0.531 0.469
E32.0 Persistent hyperplasia of thymus
0.000 0.531 0.469
B37.7 Candidal septicaemia
0.000 0.531 0.469
M11.9 Crystal arthropathy, unspecified
0.467 0.532 0.000
E32.8 Other diseases of thymus
0.000 0.535 0.464
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.536 0.464
E03 Other hypothyroidism
0.126 0.537 0.337
E21.2 Other hyperparathyroidism
0.000 0.537 0.463
M11.1 Familial chondrocalcinosis
0.463 0.537 0.000
M11.0 Hydroxyapatite deposition disease
0.463 0.537 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.462 0.538 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.539 0.460
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.459 0.541 0.000
M14.4 Arthropathy in amyloidosis
0.459 0.541 0.000
M14.3 Lipoid dermatoarthritis
0.459 0.541 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.459 0.541 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.459 0.541 0.000
D86.3 Sarcoidosis of skin
0.000 0.542 0.458
E34.9 Endocrine disorder, unspecified
0.000 0.549 0.451
G36.0 Neuromyelitis optica [Devic]
0.000 0.550 0.450
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.551 0.449
E53.1 Pyridoxine deficiency
0.000 0.553 0.447
E53.0 Riboflavin deficiency
0.000 0.553 0.447
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.554 0.446
D59 Acquired haemolytic anaemia
0.000 0.554 0.446
D86.9 Sarcoidosis, unspecified
0.000 0.555 0.445
G44 Other headache syndromes
0.000 0.556 0.444
M11.2 Other chondrocalcinosis
0.443 0.557 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.442 0.557 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.442 0.557 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.442 0.557 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.442 0.557 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.442 0.557 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.442 0.557 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.442 0.557 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.442 0.557 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.559 0.440
E34.3 Short stature, not elsewhere classified
0.000 0.560 0.440
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.560 0.440
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.562 0.438
E45 Retarded development following protein-energy malnutrition
0.000 0.562 0.438
E43 Unspecified severe protein-energy malnutrition
0.000 0.562 0.438
E42 Marasmic kwashiorkor
0.000 0.562 0.438
E41 Nutritional marasmus
0.000 0.562 0.438
E40 Kwashiorkor
0.000 0.562 0.438
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.564 0.436
E53.9 Vitamin B deficiency, unspecified
0.000 0.565 0.435
D69 Purpura and other haemorrhagic conditions
0.000 0.565 0.435
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.566 0.434
M14.2 Diabetic arthropathy
0.432 0.567 0.000
E61.1 Iron deficiency
0.000 0.571 0.429
B25-B34 Other viral diseases
0.000 0.572 0.428
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.573 0.427
D72 Other disorders of white blood cells
0.000 0.575 0.425
G41 Status epilepticus
0.000 0.581 0.419
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.581 0.419
D51.2 Transcobalamin II deficiency
0.000 0.581 0.419
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.581 0.419
M12.30 Palindromic rheumatism (Multiple sites)
0.418 0.582 0.000
D68 Other coagulation defects
0.000 0.584 0.416
D82 Immunodeficiency associated with other major defects
0.000 0.585 0.415
D59.1 Other autoimmune haemolytic anaemias
0.000 0.586 0.414
A80-A89 Viral infections of the central nervous system
0.000 0.586 0.414
D72.8 Other specified disorders of white blood cells
0.000 0.586 0.414
E50.9 Vitamin A deficiency, unspecified
0.000 0.586 0.414
E50.8 Other manifestations of vitamin A deficiency
0.000 0.586 0.414
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.586 0.414
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.586 0.414
E50.5 Vitamin A deficiency with night blindness
0.000 0.586 0.414
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.586 0.414
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.586 0.414
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.586 0.414
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.586 0.414
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.586 0.414
E63.9 Nutritional deficiency, unspecified
0.000 0.586 0.414
E63.8 Other specified nutritional deficiencies
0.000 0.586 0.414
E63.1 Imbalance of constituents of food intake
0.000 0.586 0.414
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.586 0.414
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.586 0.414
E64.8 Sequelae of other nutritional deficiencies
0.000 0.586 0.414
E64.3 Sequelae of rickets
0.000 0.586 0.414
E64.2 Sequelae of vitamin C deficiency
0.000 0.586 0.414
E64.1 Sequelae of vitamin A deficiency
0.000 0.586 0.414
E64.0 Sequelae of protein-energy malnutrition
0.000 0.586 0.414
D84 Other immunodeficiencies
0.000 0.587 0.413
M11.8 Other specified crystal arthropathies
0.412 0.588 0.000
D52.8 Other folate deficiency anaemias
0.000 0.589 0.410
D52.1 Drug-induced folate deficiency anaemia
0.000 0.589 0.410
D52.0 Dietary folate deficiency anaemia
0.000 0.589 0.410
E28.9 Ovarian dysfunction, unspecified
0.000 0.590 0.409
E28.8 Other ovarian dysfunction
0.000 0.590 0.409
E28.1 Androgen excess
0.000 0.590 0.409
E28.0 Oestrogen excess
0.000 0.590 0.409
E26 Hyperaldosteronism
0.001 0.591 0.407
E28.2 Polycystic ovarian syndrome
0.000 0.591 0.408
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.594 0.406
B37.0 Candidal stomatitis
0.000 0.596 0.404
B01 Varicella [chickenpox]
0.000 0.597 0.403
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.597 0.403
E61.9 Deficiency of nutrient element, unspecified
0.000 0.598 0.402
E61.8 Deficiency of other specified nutrient elements
0.000 0.598 0.402
E61.7 Deficiency of multiple nutrient elements
0.000 0.598 0.402
E61.6 Vanadium deficiency
0.000 0.598 0.402
E61.5 Molybdenum deficiency
0.000 0.598 0.402
E61.4 Chromium deficiency
0.000 0.598 0.402
E61.3 Manganese deficiency
0.000 0.598 0.402
E61.0 Copper deficiency
0.000 0.598 0.402
E25.9 Adrenogenital disorder, unspecified
0.000 0.598 0.402
E25.8 Other adrenogenital disorders
0.000 0.598 0.402
E23 Hypofunction and other disorders of pituitary gland
0.000 0.600 0.400
B25 Cytomegaloviral disease
0.000 0.600 0.400
E29 Testicular dysfunction
0.001 0.600 0.399
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.399 0.601 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.399 0.601 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.399 0.601 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.399 0.601 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.399 0.601 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.399 0.601 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.399 0.601 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.399 0.601 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.399 0.601 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.399 0.601 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.399 0.601 0.000
M08.28 Juvenile arthritis with systemic onset (Other)
0.399 0.601 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.399 0.601 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.399 0.601 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.399 0.601 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.399 0.601 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.399 0.601 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.399 0.601 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.399 0.601 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.399 0.601 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.399 0.601 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.399 0.601 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.399 0.601 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.399 0.601 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.399 0.601 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.399 0.601 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.399 0.601 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.399 0.601 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.399 0.601 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.399 0.601 0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.399 0.601 0.000
M08.48 Pauciarticular juvenile arthritis (Other)
0.399 0.601 0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.399 0.601 0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.399 0.601 0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.399 0.601 0.000
M08.44 Pauciarticular juvenile arthritis (Hand)
0.399 0.601 0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.399 0.601 0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.399 0.601 0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)
0.399 0.601 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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