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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9275698
log Bayes Factor = 38.0121
Chromosome 6   position 32,687,973  (GRCh37) Explore rs9275698 on Ensembl!
Variant rs9275698 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.997 0.003 0.000
E03 Other hypothyroidism
0.996 0.004 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.005 0.995
M06.3 Rheumatoid nodule
0.000 0.006 0.994
E03.9 Hypothyroidism, unspecified
0.994 0.006 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
N18 Chronic renal failure
0.975 0.025 0.000
N17-N19 Renal failure
0.969 0.031 0.000
N17 Acute renal failure
0.963 0.037 0.000
N18.5 Chronic kidney disease, stage 5
0.961 0.039 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.050 0.950
N17.9 Acute renal failure, unspecified
0.950 0.050 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.057 0.943
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.061 0.939
M06.0 Seronegative rheumatoid arthritis
0.000 0.063 0.937
N18.4 Chronic kidney disease, stage 4
0.932 0.068 0.000
N04 Nephrotic syndrome
0.928 0.072 0.000
N04.9 Unspecified
0.927 0.073 0.000
N18.0 End-stage renal disease
0.926 0.074 0.000
N00-N08 Glomerular diseases
0.925 0.075 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.078 0.922
N18.9 Chronic renal failure, unspecified
0.916 0.084 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.095 0.905
M07 Psoriatic and enteropathic arthropathies
0.000 0.097 0.903
Chapter IV Endocrine, nutritional and metabolic diseases
0.898 0.102 0.000
N05 Unspecified nephritic syndrome
0.890 0.110 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.118 0.882
D80-D89 Certain disorders involving the immune mechanism
0.881 0.119 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.880 0.120 0.000
E03.8 Other specified hypothyroidism
0.879 0.121 0.000
Chapter XIV Diseases of the genitourinary system
0.878 0.122 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.129 0.871
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.870 0.130 0.000
N17.0 Acute renal failure with tubular necrosis
0.868 0.132 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.866 0.134 0.000
# Top node
0.865 0.135 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.137 0.863
Q38-Q45 Other congenital malformations of the digestive system
0.861 0.139 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.140 0.860
D69 Purpura and other haemorrhagic conditions
0.857 0.143 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.857 0.143 0.000
D69.6 Thrombocytopenia, unspecified
0.853 0.147 0.000
N05.2 Diffuse membranous glomerulonephritis
0.849 0.151 0.000
D86 Sarcoidosis
0.844 0.156 0.000
M07.3 Other psoriatic arthropathies
0.000 0.157 0.843
M06.4 Inflammatory polyarthropathy
0.000 0.164 0.836
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.833 0.167 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.827 0.173 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.825 0.174 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.819 0.181 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.817 0.183 0.000
L40-L45 Papulosquamous disorders
0.808 0.184 0.008
E20-E35 Disorders of other endocrine glands
0.815 0.185 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.186 0.814
M12 Other specific arthropathies
0.000 0.188 0.812
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.189 0.811
L43 Lichen planus
0.807 0.191 0.003
N03 Chronic nephritic syndrome
0.808 0.192 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.807 0.193 0.000
L10-L14 Bullous disorders
0.805 0.195 0.000
L43.9 Lichen planus, unspecified
0.805 0.195 0.000
L50-L54 Urticaria and erythema
0.802 0.198 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.801 0.199 0.000
Q44.6 Cystic disease of liver
0.798 0.202 0.000
D73 Diseases of spleen
0.793 0.207 0.000
Q60-Q64 Congenital malformations of the urinary system
0.793 0.207 0.000
N18.8 Other chronic renal failure
0.792 0.208 0.000
L13 Other bullous disorders
0.790 0.210 0.000
E40-E46 Malnutrition
0.788 0.212 0.000
N04.1 Focal and segmental glomerular lesions
0.781 0.219 0.000
D73.5 Infarction of spleen
0.781 0.219 0.000
L13.0 Dermatitis herpetiformis
0.780 0.220 0.000
D86.9 Sarcoidosis, unspecified
0.771 0.229 0.000
L53 Other erythematous conditions
0.768 0.232 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.233 0.767
Q50-Q56 Congenital malformations of genital organs
0.765 0.235 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.763 0.237 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.237 0.763
Q61 Cystic kidney disease
0.761 0.239 0.000
D69.2 Other nonthrombocytopenic purpura
0.759 0.241 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.245 0.755
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.751 0.249 0.000
N04.0 Minor glomerular abnormality
0.751 0.249 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.250 0.750
Q43 Other congenital malformations of intestine
0.750 0.250 0.000
E24 Cushing's syndrome
0.748 0.252 0.000
E06 Thyroiditis
0.748 0.252 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.255 0.745
D80 Immunodeficiency with predominantly antibody defects
0.744 0.256 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.743 0.257 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.741 0.259 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.260 0.740
Q12 Congenital lens malformations
0.736 0.264 0.000
D69.4 Other primary thrombocytopenia
0.735 0.265 0.000
L52 Erythema nodosum
0.733 0.267 0.000
D86.0 Sarcoidosis of lung
0.730 0.270 0.000
Q61.2 Polycystic kidney, adult type
0.723 0.277 0.000
N04.2 Diffuse membranous glomerulonephritis
0.723 0.277 0.000
N05.9 Unspecified
0.720 0.280 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
D69.9 Haemorrhagic condition, unspecified
0.717 0.283 0.000
I12.0 Hypertensive renal disease with renal failure
0.717 0.283 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.716
M05.1 Rheumatoid lung disease
0.000 0.283 0.716
M05.0 Felty's syndrome
0.000 0.283 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
I12 Hypertensive renal disease
0.715 0.285 0.000
L53.9 Erythematous condition, unspecified
0.715 0.285 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.715 0.285 0.000
E00 Congenital iodine-deficiency syndrome
0.715 0.285 0.000
E03.5 Myxoedema coma
0.714 0.286 0.000
E03.4 Atrophy of thyroid (acquired)
0.714 0.286 0.000
E03.3 Postinfectious hypothyroidism
0.714 0.286 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.714 0.286 0.000
N05.1 Focal and segmental glomerular lesions
0.714 0.286 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.287 0.713
M06.38 Rheumatoid nodule (Other)
0.000 0.287 0.713
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.287 0.713
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.287 0.713
M06.33 Rheumatoid nodule (Forearm)
0.000 0.287 0.713
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.287 0.713
I12.9 Hypertensive renal disease without renal failure
0.713 0.287 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.711 0.289 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.290 0.710
Q61.3 Polycystic kidney, unspecified
0.709 0.291 0.000
E46 Unspecified protein-energy malnutrition
0.709 0.291 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.705 0.294 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.300 0.700
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.301 0.699
Q44.5 Other congenital malformations of bile ducts
0.698 0.302 0.000
N18.1 Chronic kidney disease, stage 1
0.697 0.303 0.000
M08 Juvenile arthritis
0.000 0.308 0.692
N17.2 Acute renal failure with medullary necrosis
0.690 0.309 0.000
D89.1 Cryoglobulinaemia
0.690 0.310 0.000
Q12.0 Congenital cataract
0.689 0.311 0.000
Q00-Q07 Congenital malformations of the nervous system
0.685 0.315 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.685 0.315 0.000
D73.1 Hypersplenism
0.684 0.316 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.319 0.681
D69.8 Other specified haemorrhagic conditions
0.680 0.320 0.000
E23 Hypofunction and other disorders of pituitary gland
0.679 0.321 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.322 0.678
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.324 0.676
N17.8 Other acute renal failure
0.673 0.327 0.000
N00 Acute nephritic syndrome
0.673 0.327 0.000
Q15 Other congenital malformations of eye
0.673 0.327 0.000
E34 Other endocrine disorders
0.673 0.327 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.328 0.672
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.328 0.672
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.328 0.672
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.328 0.672
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.328 0.672
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.328 0.672
Q40 Other congenital malformations of upper alimentary tract
0.669 0.331 0.000
N18.3 Chronic kidney disease, stage 3
0.668 0.332 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.667 0.333 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.667 0.333 0.000
D86.8 Sarcoidosis of other and combined sites
0.667 0.333 0.000
N04.8 Other
0.665 0.335 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.665 0.335 0.000
N04.6 Dense deposit disease
0.665 0.335 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.665 0.335 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.665 0.335 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.665 0.335 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.664 0.336 0.000
N03.9 Unspecified
0.663 0.337 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.663 0.337 0.000
N06 Isolated proteinuria with specified morphological lesion
0.663 0.337 0.000
N01 Rapidly progressive nephritic syndrome
0.663 0.337 0.000
D83 Common variable immunodeficiency
0.661 0.339 0.000
N03.1 Focal and segmental glomerular lesions
0.660 0.340 0.000
Q39 Congenital malformations of oesophagus
0.657 0.343 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.344 0.656
L53.0 Toxic erythema
0.654 0.346 0.000
D82 Immunodeficiency associated with other major defects
0.654 0.346 0.000
M11 Other crystal arthropathies
0.000 0.347 0.653
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.651 0.348 0.000
Chapter XXII Codes for special purposes
0.651 0.349 0.000
M12.3 Palindromic rheumatism
0.000 0.350 0.650
Q38.1 Ankyloglossia
0.650 0.350 0.000
M12.2 Villonodular synovitis (pigmented)
0.000 0.351 0.649
Q43.8 Other specified congenital malformations of intestine
0.649 0.351 0.000
E03.1 Congenital hypothyroidism without goitre
0.649 0.351 0.000
L43.8 Other lichen planus
0.647 0.351 0.001
M07.5 Arthropathy in ulcerative colitis
0.000 0.352 0.648
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.352 0.648
M07.2 Psoriatic spondylitis
0.000 0.352 0.648
M07.1 Arthritis mutilans
0.000 0.352 0.648
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.352 0.648
L51 Erythema multiforme
0.648 0.352 0.000
D70 Agranulocytosis
0.646 0.354 0.000
N03.8 Other
0.645 0.355 0.000
Q55 Other congenital malformations of male genital organs
0.643 0.357 0.000
N05.6 Dense deposit disease
0.638 0.362 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.638 0.362 0.000
N05.0 Minor glomerular abnormality
0.638 0.362 0.000
Q14 Congenital malformations of posterior segment of eye
0.636 0.364 0.000
E24.0 Pituitary-dependent Cushing's disease
0.635 0.365 0.000
D73.3 Abscess of spleen
0.635 0.365 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.634 0.366 0.000
D81 Combined immunodeficiencies
0.632 0.368 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.370 0.630
D86.1 Sarcoidosis of lymph nodes
0.629 0.371 0.000
E16 Other disorders of pancreatic internal secretion
0.628 0.372 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.626 0.373 0.000
E24.2 Drug-induced Cushing's syndrome
0.625 0.375 0.000
D67 Hereditary factor IX deficiency
0.625 0.375 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.375 0.625
D89.3 Immune reconstitution syndrome
0.623 0.376 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.622 0.378 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.621 0.379 0.000
Q35-Q37 Cleft lip and cleft palate
0.621 0.379 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.621 0.379 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.620 0.380 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.618 0.382 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.618 0.382 0.000
D69.1 Qualitative platelet defects
0.615 0.385 0.000
M07.6 Other enteropathic arthropathies
0.000 0.386 0.613
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.613 0.387 0.000
L11 Other acantholytic disorders
0.613 0.387 0.000
L44 Other papulosquamous disorders
0.607 0.388 0.006
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.391 0.609
Q53 Undescended testicle
0.607 0.392 0.000
E23.2 Diabetes insipidus
0.605 0.395 0.000
E05.8 Other thyrotoxicosis
0.604 0.395 0.000
Q38.8 Other congenital malformations of pharynx
0.604 0.396 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.396 0.604
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.396 0.604
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.396 0.604
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.396 0.604
E26 Hyperaldosteronism
0.603 0.397 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.400 0.600
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.400 0.600
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.400 0.600
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.400 0.600
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.400 0.600
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.400 0.600
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.400 0.600
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.598 0.402 0.000
E31 Polyglandular dysfunction
0.598 0.402 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.598 0.402 0.000
Q44.7 Other congenital malformations of liver
0.598 0.402 0.000
Q44.4 Choledochal cyst
0.598 0.402 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.598 0.402 0.000
Q44.2 Atresia of bile ducts
0.598 0.402 0.000
Q44.1 Other congenital malformations of gallbladder
0.598 0.402 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.598 0.402 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.597 0.403 0.000
D73.9 Disease of spleen, unspecified
0.597 0.403 0.000
Q17 Other congenital malformations of ear
0.596 0.404 0.000
E24.9 Cushing's syndrome, unspecified
0.595 0.405 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.592 0.407 0.000
E25 Adrenogenital disorders
0.590 0.410 0.000
Q43.0 Meckel's diverticulum
0.589 0.411 0.000
D73.4 Cyst of spleen
0.589 0.411 0.000
D74 Methaemoglobinaemia
0.587 0.413 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.587 0.413 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.587 0.413 0.000
I10-I15 Hypertensive diseases
0.587 0.413 0.000
Q50.5 Embryonic cyst of broad ligament
0.587 0.413 0.000
L41 Parapsoriasis
0.579 0.415 0.006
L45 Papulosquamous disorders in diseases classified elsewhere
0.579 0.415 0.006
E35 Disorders of endocrine glands in diseases classified elsewhere
0.584 0.416 0.000
E32 Diseases of thymus
0.584 0.416 0.000
E30 Disorders of puberty, not elsewhere classified
0.584 0.416 0.000
Q45 Other congenital malformations of digestive system
0.584 0.416 0.000
D86.3 Sarcoidosis of skin
0.583 0.417 0.000
Q38.7 Pharyngeal pouch
0.583 0.417 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.418 0.582
M12.4 Intermittent hydrarthrosis
0.000 0.418 0.582
M12.1 Kaschin-Beck disease
0.000 0.418 0.582
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.418 0.582
Q15.0 Congenital glaucoma
0.581 0.419 0.000
L43.3 Subacute (active) lichen planus
0.578 0.420 0.002
L43.2 Lichenoid drug reaction
0.578 0.420 0.002
L43.1 Bullous lichen planus
0.578 0.420 0.002
L43.0 Hypertrophic lichen planus
0.578 0.420 0.002
L53.8 Other specified erythematous conditions
0.579 0.421 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.421 0.579
N03.7 Diffuse crescentic glomerulonephritis
0.579 0.421 0.000
N03.6 Dense deposit disease
0.579 0.421 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.579 0.421 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.579 0.421 0.000
N03.2 Diffuse membranous glomerulonephritis
0.579 0.421 0.000
N03.0 Minor glomerular abnormality
0.579 0.421 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.579 0.421 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.579 0.421 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.579 0.421 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.579 0.421 0.000
L10 Pemphigus
0.577 0.423 0.000
L14 Bullous disorders in diseases classified elsewhere
0.577 0.423 0.000
L54 Erythema in diseases classified elsewhere
0.575 0.425 0.000
E06.3 Autoimmune thyroiditis
0.574 0.426 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.574 0.426 0.000
Q13 Congenital malformations of anterior segment of eye
0.574 0.426 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.574 0.426 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.574 0.426 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.574 0.426 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.570 0.430 0.000
D73.2 Chronic congestive splenomegaly
0.569 0.431 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.569 0.431 0.000
L13.9 Bullous disorder, unspecified
0.566 0.433 0.000
L13.8 Other specified bullous disorders
0.566 0.433 0.000
L13.1 Subcorneal pustular dermatitis
0.566 0.433 0.000
N25-N29 Other disorders of kidney and ureter
0.566 0.434 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.565 0.435 0.000
E45 Retarded development following protein-energy malnutrition
0.565 0.435 0.000
E43 Unspecified severe protein-energy malnutrition
0.565 0.435 0.000
E42 Marasmic kwashiorkor
0.565 0.435 0.000
E41 Nutritional marasmus
0.565 0.435 0.000
E40 Kwashiorkor
0.565 0.435 0.000
E29 Testicular dysfunction
0.561 0.439 0.000
Q64 Other congenital malformations of urinary system
0.561 0.439 0.000
E23.6 Other disorders of pituitary gland
0.560 0.439 0.000
N05.8 Other
0.560 0.440 0.000
E06.9 Thyroiditis, unspecified
0.556 0.444 0.000
E28 Ovarian dysfunction
0.555 0.445 0.000
L51.9 Erythema multiforme, unspecified
0.552 0.447 0.000
E34.3 Short stature, not elsewhere classified
0.551 0.449 0.000
L53.3 Other chronic figurate erythema
0.551 0.449 0.000
L53.2 Erythema marginatum
0.551 0.449 0.000
L53.1 Erythema annulare centrifugum
0.551 0.449 0.000
Q04 Other congenital malformations of brain
0.549 0.451 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.548 0.451 0.000
Q52 Other congenital malformations of female genitalia
0.548 0.452 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.547 0.453 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.547 0.453 0.000
Q38.3 Other congenital malformations of tongue
0.547 0.453 0.000
Q38.2 Macroglossia
0.547 0.453 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.547 0.453 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.547 0.453 0.000
Q38.6 Other congenital malformations of mouth
0.546 0.454 0.000
Q61.8 Other cystic kidney diseases
0.546 0.454 0.000
Q61.1 Polycystic kidney, infantile type
0.546 0.454 0.000
Q07 Other congenital malformations of nervous system
0.543 0.456 0.000
Chapter IX Diseases of the circulatory system
0.543 0.457 0.000
M12.5 Traumatic arthropathy
0.000 0.458 0.542
L12 Pemphigoid
0.541 0.458 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.459 0.541
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.459 0.541
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.459 0.541
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.459 0.541
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.459 0.541
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.459 0.541
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.459 0.541
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.459 0.541
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.459 0.541
Q40.3 Congenital malformation of stomach, unspecified
0.540 0.460 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.539 0.461 0.000
Q43.7 Persistent cloaca
0.538 0.462 0.000
Q43.6 Congenital fistula of rectum and anus
0.538 0.462 0.000
Q43.5 Ectopic anus
0.538 0.462 0.000
Q43.4 Duplication of intestine
0.538 0.462 0.000
Q43.2 Other congenital functional disorders of colon
0.538 0.462 0.000
E22 Hyperfunction of pituitary gland
0.537 0.463 0.000
Q55.6 Other congenital malformations of penis
0.537 0.463 0.000
E24.8 Other Cushing's syndrome
0.536 0.463 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.536 0.463 0.000
E24.3 Ectopic ACTH syndrome
0.536 0.463 0.000
E24.1 Nelson's syndrome
0.536 0.463 0.000
E06.4 Drug-induced thyroiditis
0.536 0.463 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.536 0.463 0.000
E06.1 Subacute thyroiditis
0.536 0.463 0.000
E06.0 Acute thyroiditis
0.536 0.463 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.464 0.535
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.465 0.535
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.465 0.535
D80.8 Other immunodeficiencies with predominantly antibody defects
0.534 0.466 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.534 0.466 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.534 0.466 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.534 0.466 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.534 0.466 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.534 0.466 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.532 0.468 0.000
E15 Nondiabetic hypoglycaemic coma
0.531 0.469 0.000
Q12.9 Congenital lens malformation, unspecified
0.528 0.472 0.000
Q12.8 Other congenital lens malformations
0.528 0.472 0.000
Q12.4 Spherophakia
0.528 0.472 0.000
Q12.3 Congenital aphakia
0.528 0.472 0.000
Q12.2 Coloboma of lens
0.528 0.472 0.000
Q12.1 Congenital displaced lens
0.528 0.472 0.000
D75 Other diseases of blood and blood-forming organs
0.526 0.474 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.000 0.477 0.523
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.522 0.478 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.520 0.480 0.000
Q39.9 Congenital malformation of oesophagus, unspecified
0.520 0.480 0.000
E34.8 Other specified endocrine disorders
0.519 0.480 0.000
Q14.1 Congenital malformation of retina
0.517 0.483 0.000
Q39.6 Diverticulum of oesophagus
0.516 0.484 0.000
D55-D59 Haemolytic anaemias
0.515 0.485 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.485 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M05.28 Rheumatoid vasculitis (Other)
0.000 0.486 0.514
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.486 0.514
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.486 0.514
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.486 0.514
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.486 0.514
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.486 0.514
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.486 0.514
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.486 0.514
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.486 0.514
M05.08 Felty's syndrome (Other)
0.000 0.486 0.514
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.486 0.514
M05.06 Felty's syndrome (Lower leg)
0.000 0.486 0.514
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.486 0.514
M05.04 Felty's syndrome (Hand)
0.000 0.486 0.514
M05.03 Felty's syndrome (Forearm)
0.000 0.486 0.514
M05.02 Felty's syndrome (Upper arm)
0.000 0.486 0.514
M05.01 Felty's syndrome (Shoulder region)
0.000 0.486 0.514
M05.00 Felty's syndrome (Multiple sites)
0.000 0.486 0.514
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.486 0.514
M05.18 Rheumatoid lung disease (Other)
0.000 0.486 0.514
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.486 0.514
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.486 0.514
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.486 0.514
M05.14 Rheumatoid lung disease (Hand)
0.000 0.486 0.514
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.486 0.514
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.486 0.514
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.486 0.514
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.486 0.514
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.486 0.514
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.486 0.514
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.486 0.514
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.486 0.514
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.486 0.514
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.486 0.514
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.486 0.514
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.486 0.514
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.486 0.514
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.513
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.513
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.513
Q61.4 Renal dysplasia
0.513 0.487 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.512 0.487 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.512 0.487 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.512 0.487 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.512 0.487 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.512 0.487 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.512 0.487 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.512 0.487 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.512 0.487 0.000
D69.0 Allergic purpura
0.512 0.488 0.000
Q61.9 Cystic kidney disease, unspecified
0.510 0.490 0.000
E06.5 Other chronic thyroiditis
0.508 0.492 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.506 0.494 0.000
D83.9 Common variable immunodeficiency, unspecified
0.504 0.496 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.503 0.497 0.000
L42 Pityriasis rosea
0.496 0.497 0.006
Q43.3 Congenital malformations of intestinal fixation
0.502 0.498 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.501 0.499 0.000
Q61.0 Congenital single renal cyst
0.501 0.499 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.501 0.499 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.498 0.502 0.000
M08.8 Other juvenile arthritis
0.000 0.504 0.496
M08.4 Pauciarticular juvenile arthritis
0.000 0.504 0.496

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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