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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9276598
log Bayes Factor = 105.033
Chromosome 6   position 32,733,987  (GRCh37) Explore rs9276598 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.998 0.002 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E10.2 With renal complications
0.000 0.006 0.994
E50-E64 Other nutritional deficiencies
0.000 0.038 0.962
E10.4 With neurological complications
0.000 0.046 0.954
E10.5 With peripheral circulatory complications
0.000 0.052 0.948
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.066 0.934
L40 Psoriasis
0.931 0.068 0.000
E55 Vitamin D deficiency
0.000 0.073 0.927
E14 Unspecified diabetes mellitus
0.000 0.086 0.914
D86.9 Sarcoidosis, unspecified
0.000 0.087 0.913
G37 Other demyelinating diseases of central nervous system
0.000 0.088 0.912
D86 Sarcoidosis
0.000 0.095 0.905
E55.9 Vitamin D deficiency, unspecified
0.000 0.098 0.902
D86.0 Sarcoidosis of lung
0.000 0.120 0.880
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.151 0.849
L40.5 Arthropathic psoriasis
0.845 0.155 0.000
L40.0 Psoriasis vulgaris
0.824 0.176 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.191 0.809
E14.8 With unspecified complications
0.000 0.200 0.799
M06.9 Rheumatoid arthritis, unspecified
0.798 0.202 0.000
M06 Other rheumatoid arthritis
0.793 0.207 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.788 0.212 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.212 0.788
E10.7 With multiple complications
0.000 0.212 0.788
D86.8 Sarcoidosis of other and combined sites
0.000 0.213 0.787
E14.3 With ophthalmic complications
0.000 0.214 0.786
E40-E46 Malnutrition
0.000 0.217 0.783
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.226 0.774
D80-D89 Certain disorders involving the immune mechanism
0.000 0.230 0.770
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.235 0.765
E14.6 With other specified complications
0.000 0.237 0.763
E53 Deficiency of other B group vitamins
0.000 0.238 0.762
E10.0 With coma
0.000 0.240 0.760
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.752 0.248 0.000
M06.3 Rheumatoid nodule
0.751 0.249 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.266 0.734
M06.0 Seronegative rheumatoid arthritis
0.731 0.269 0.000
E10.8 With unspecified complications
0.000 0.274 0.726
D86.1 Sarcoidosis of lymph nodes
0.000 0.275 0.725
E10.6 With other specified complications
0.000 0.278 0.722
M05.9 Seropositive rheumatoid arthritis, unspecified
0.720 0.280 0.000
M05 Seropositive rheumatoid arthritis
0.720 0.280 0.000
M05-M14 Inflammatory polyarthropathies
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E51 Thiamine deficiency
0.000 0.287 0.712
E61 Deficiency of other nutrient elements
0.000 0.292 0.708
E14.2 Withrenal complications
0.000 0.294 0.706
G36 Other acute disseminated demyelination
0.000 0.299 0.700
E20-E35 Disorders of other endocrine glands
0.000 0.304 0.696
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.691 0.309 0.000
E27 Other disorders of adrenal gland
0.000 0.310 0.690
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.310 0.690
E63 Other nutritional deficiencies
0.000 0.310 0.690
E50 Vitamin A deficiency
0.000 0.310 0.690
E60 Dietary zinc deficiency
0.000 0.310 0.690
E59 Dietary selenium deficiency
0.000 0.310 0.690
E54 Ascorbic acid deficiency
0.000 0.310 0.690
E52 Niacin deficiency [pellagra]
0.000 0.310 0.690
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.310 0.690
E27.1 Primary adrenocortical insufficiency
0.000 0.311 0.689
L40.1 Generalised pustular psoriasis
0.687 0.312 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.314 0.686
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.315 0.685
L40.4 Guttate psoriasis
0.682 0.318 0.000
L40.3 Pustulosis palmaris et plantaris
0.680 0.319 0.000
E56 Other vitamin deficiencies
0.000 0.320 0.680
E13 Other specified diabetes mellitus
0.000 0.330 0.670
L40.2 Acrodermatitis continua
0.668 0.332 0.000
E55.0 Rickets, active
0.000 0.335 0.664
K90 Intestinal malabsorption
0.000 0.336 0.664
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.662 0.338 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.655 0.345 0.000
E14.7 With multiple complications
0.000 0.345 0.655
E14.0 With coma
0.000 0.345 0.655
G37.5 Concentric sclerosis [Balo]
0.000 0.346 0.654
G37.4 Subacute necrotising myelitis
0.000 0.346 0.654
G37.2 Central pontine myelinolysis
0.000 0.346 0.654
G37.1 Central demyelination of corpus callosum
0.000 0.346 0.654
G37.0 Diffuse sclerosis
0.000 0.346 0.654
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.348 0.652
E14.9 Without complications
0.000 0.350 0.650
M06.32 Rheumatoid nodule (Upper arm)
0.644 0.356 0.000
E58 Dietary calcium deficiency
0.000 0.356 0.644
M06.34 Rheumatoid nodule (Hand)
0.642 0.358 0.000
E14.5 With peripheral circulatory complications
0.000 0.369 0.631
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.370 0.630
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.628 0.372 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.373 0.627
E53.9 Vitamin B deficiency, unspecified
0.000 0.380 0.620
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.610 0.390 0.000
M06.33 Rheumatoid nodule (Forearm)
0.605 0.395 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.605 0.395 0.000
L40-L45 Papulosquamous disorders
0.572 0.399 0.029
L40.8 Other psoriasis
0.600 0.399 0.000
E61.2 Magnesium deficiency
0.000 0.400 0.600
K90.9 Intestinal malabsorption, unspecified
0.000 0.402 0.598
D82 Immunodeficiency associated with other major defects
0.000 0.404 0.596
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.595 0.405 0.000
E04 Other non-toxic goitre
0.000 0.407 0.593
E14.1 With ketoacidosis
0.000 0.413 0.587
M06.36 Rheumatoid nodule (Lower leg)
0.581 0.419 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.581 0.419 0.000
D86.3 Sarcoidosis of skin
0.000 0.422 0.578
E27.2 Addisonian crisis
0.000 0.427 0.573
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.573 0.427 0.000
M06.1 Adult-onset Still's disease
0.572 0.428 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.570 0.430 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.570 0.430 0.000
M06.2 Rheumatoid bursitis
0.568 0.431 0.000
M14 Arthropathies in other diseases classified elsewhere
0.567 0.433 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.567 0.433 0.000
M05.1 Rheumatoid lung disease
0.565 0.435 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.435 0.564
E07 Other disorders of thyroid
0.000 0.437 0.563
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.563 0.437 0.000
M06.4 Inflammatory polyarthropathy
0.562 0.437 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.439 0.561
E45 Retarded development following protein-energy malnutrition
0.000 0.439 0.561
E43 Unspecified severe protein-energy malnutrition
0.000 0.439 0.561
E42 Marasmic kwashiorkor
0.000 0.439 0.561
E41 Nutritional marasmus
0.000 0.439 0.561
E40 Kwashiorkor
0.000 0.439 0.561
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.561 0.439 0.000
E06 Thyroiditis
0.000 0.440 0.560
E20 Hypoparathyroidism
0.000 0.441 0.559
D81 Combined immunodeficiencies
0.000 0.448 0.552
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.552 0.448 0.000
M05.8 Other seropositive rheumatoid arthritis
0.551 0.449 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.547 0.453 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.547 0.453 0.000
E53.1 Pyridoxine deficiency
0.000 0.453 0.546
E53.0 Riboflavin deficiency
0.000 0.453 0.546
E53.8 Deficiency of other specified B group vitamins
0.000 0.455 0.545
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.543 0.457 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.458 0.542
M08 Juvenile arthritis
0.541 0.459 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.539 0.461 0.000
M06.38 Rheumatoid nodule (Other)
0.539 0.461 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.539 0.461 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.539 0.461 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.536 0.464 0.000
E51.2 Wernicke's encephalopathy
0.000 0.466 0.533
G36.0 Neuromyelitis optica [Devic]
0.000 0.467 0.533
E05.8 Other thyrotoxicosis
0.000 0.468 0.531
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.529 0.471 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.473 0.527
D89.3 Immune reconstitution syndrome
0.000 0.474 0.526
M06.08 Seronegative rheumatoid arthritis (Other)
0.524 0.476 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.524 0.476 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.524 0.476 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.524 0.476 0.000
E34 Other endocrine disorders
0.000 0.482 0.518
D83 Common variable immunodeficiency
0.000 0.483 0.517
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.516 0.483 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.516 0.484 0.000
M05.0 Felty's syndrome
0.516 0.484 0.000
M06.8 Other specified rheumatoid arthritis
0.516 0.484 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.516 0.484 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M11 Other crystal arthropathies
0.513 0.487 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.488 0.512
E51.9 Thiamine deficiency, unspecified
0.000 0.489 0.511
E51.8 Other manifestations of thiamine deficiency
0.000 0.489 0.511
E51.1 Beriberi
0.000 0.489 0.511
E31 Polyglandular dysfunction
0.000 0.490 0.510
E61.9 Deficiency of nutrient element, unspecified
0.000 0.492 0.507
E61.8 Deficiency of other specified nutrient elements
0.000 0.492 0.507
E61.7 Deficiency of multiple nutrient elements
0.000 0.492 0.507
E61.6 Vanadium deficiency
0.000 0.492 0.507
E61.5 Molybdenum deficiency
0.000 0.492 0.507
E61.4 Chromium deficiency
0.000 0.492 0.507
E61.3 Manganese deficiency
0.000 0.492 0.507
E61.0 Copper deficiency
0.000 0.492 0.507
G36.9 Acute disseminated demyelination, unspecified
0.000 0.498 0.502
G36.8 Other specified acute disseminated demyelination
0.000 0.498 0.502
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.498 0.502
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.499 0.501
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.501 0.499
E32 Diseases of thymus
0.000 0.501 0.499
E30 Disorders of puberty, not elsewhere classified
0.000 0.501 0.499
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.498 0.502 0.000
L42 Pityriasis rosea
0.481 0.505 0.014
E27.5 Adrenomedullary hyperfunction
0.000 0.505 0.495
E27.0 Other adrenocortical overactivity
0.000 0.505 0.495
E50.9 Vitamin A deficiency, unspecified
0.000 0.505 0.495
E50.8 Other manifestations of vitamin A deficiency
0.000 0.505 0.495
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.505 0.495
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.505 0.495
E50.5 Vitamin A deficiency with night blindness
0.000 0.505 0.495
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.505 0.495
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.505 0.495
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.505 0.495
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.505 0.495
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.505 0.495
E63.9 Nutritional deficiency, unspecified
0.000 0.505 0.495
E63.8 Other specified nutritional deficiencies
0.000 0.505 0.495
E63.1 Imbalance of constituents of food intake
0.000 0.505 0.495
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.505 0.495
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.505 0.495
E64.8 Sequelae of other nutritional deficiencies
0.000 0.505 0.495
E64.3 Sequelae of rickets
0.000 0.505 0.495
E64.2 Sequelae of vitamin C deficiency
0.000 0.505 0.495
E64.1 Sequelae of vitamin A deficiency
0.000 0.505 0.495
E64.0 Sequelae of protein-energy malnutrition
0.000 0.505 0.495
M05.2 Rheumatoid vasculitis
0.491 0.508 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.511 0.488
E56.9 Vitamin deficiency, unspecified
0.000 0.512 0.487
E56.8 Deficiency of other vitamins
0.000 0.512 0.487
E56.0 Deficiency of vitamin E
0.000 0.512 0.487
E14.4 With neurological complications
0.000 0.516 0.484
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.516 0.484
E13.8 With unspecified complications
0.000 0.519 0.481
E13.7 With multiple complications
0.000 0.519 0.481
E13.6 With other specified complications
0.000 0.519 0.481
E13.5 With peripheral circulatory complications
0.000 0.519 0.481
E13.4 With neurological complications
0.000 0.519 0.481
E13.2 With renal complications
0.000 0.519 0.481
E13.1 With ketoacidosis
0.000 0.519 0.481
E13.0 With coma
0.000 0.519 0.481
E13.9 Without complications
0.000 0.519 0.480
E56.1 Deficiency of vitamin K
0.000 0.522 0.477
K90.3 Pancreatic steatorrhoea
0.000 0.524 0.476
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.524 0.476
K90.1 Tropical sprue
0.000 0.524 0.476
M14.6 Neuropathic arthropathy
0.473 0.526 0.000
D82.1 Di George's syndrome
0.000 0.529 0.471
E28 Ovarian dysfunction
0.000 0.531 0.469
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.464 0.535 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.540 0.460
L44 Other papulosquamous disorders
0.438 0.543 0.019
E16.1 Other hypoglycaemia
0.001 0.543 0.456
M05.19 Rheumatoid lung disease (Site unspecified)
0.454 0.546 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.548 0.452
D84 Other immunodeficiencies
0.000 0.550 0.450
E34.8 Other specified endocrine disorders
0.000 0.551 0.449
M07 Psoriatic and enteropathic arthropathies
0.442 0.558 0.000
D89.1 Cryoglobulinaemia
0.000 0.562 0.437
E13.3 With ophthalmic complications
0.000 0.565 0.434
M12 Other specific arthropathies
0.434 0.566 0.000
L41 Parapsoriasis
0.410 0.569 0.021
L45 Papulosquamous disorders in diseases classified elsewhere
0.410 0.569 0.021
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.429 0.570 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.573 0.427
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.573 0.427
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.573 0.427
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.573 0.427
D82.2 Immunodeficiency with short-limbed stature
0.000 0.573 0.427
D82.0 Wiskott-Aldrich syndrome
0.000 0.573 0.427
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.574 0.426
E24 Cushing's syndrome
0.000 0.574 0.426
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.425 0.575 0.000
E04.8 Other specified non-toxic goitre
0.000 0.575 0.425
E06.5 Other chronic thyroiditis
0.000 0.575 0.425
M06.46 Inflammatory polyarthropathy (Lower leg)
0.424 0.576 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.422 0.578 0.000
E25 Adrenogenital disorders
0.000 0.582 0.417
K90.8 Other intestinal malabsorption
0.000 0.583 0.417
E26 Hyperaldosteronism
0.000 0.585 0.414
M06.10 Adult-onset Still's disease (Multiple sites)
0.413 0.587 0.000
M08.0 Juvenile rheumatoid arthritis
0.413 0.587 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.410 0.590 0.000
M06.18 Adult-onset Still's disease (Other)
0.410 0.590 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.410 0.590 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.410 0.590 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.410 0.590 0.000
M06.14 Adult-onset Still's disease (Hand)
0.410 0.590 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.410 0.590 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.410 0.590 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.410 0.590 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.408 0.592 0.000
M06.28 Rheumatoid bursitis (Other)
0.408 0.592 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.408 0.592 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.408 0.592 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.408 0.592 0.000
M06.24 Rheumatoid bursitis (Hand)
0.408 0.592 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.408 0.592 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.408 0.592 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.408 0.592 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.408 0.592 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.407 0.593 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.407 0.593 0.000
M14.4 Arthropathy in amyloidosis
0.407 0.593 0.000
M14.3 Lipoid dermatoarthritis
0.407 0.593 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.407 0.593 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.407 0.593 0.000
M05.18 Rheumatoid lung disease (Other)
0.405 0.595 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.405 0.595 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.405 0.595 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.405 0.595 0.000
M05.14 Rheumatoid lung disease (Hand)
0.405 0.595 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.405 0.595 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.405 0.595 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.405 0.595 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.405 0.595 0.000
E07.1 Dyshormogenetic goitre
0.000 0.596 0.404
E07.0 Hypersecretion of calcitonin
0.000 0.596 0.404
M06.48 Inflammatory polyarthropathy (Other)
0.403 0.596 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.403 0.596 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.403 0.596 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.403 0.596 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.403 0.596 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.403 0.596 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.403 0.596 0.000
M11.9 Crystal arthropathy, unspecified
0.403 0.597 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.597 0.402
E44.0 Moderate protein-energy malnutrition
0.000 0.597 0.402
E06.4 Drug-induced thyroiditis
0.000 0.598 0.402
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.598 0.402
E06.0 Acute thyroiditis
0.000 0.598 0.402
E27.9 Disorder of adrenal gland, unspecified
0.000 0.599 0.401
E20.8 Other hypoparathyroidism
0.000 0.599 0.401
E20.1 Pseudohypoparathyroidism
0.000 0.599 0.401
E20.0 Idiopathic hypoparathyroidism
0.000 0.599 0.401
E06.1 Subacute thyroiditis
0.000 0.601 0.399
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.602 0.398
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.397 0.603 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.604 0.396
D81.8 Other combined immunodeficiencies
0.000 0.604 0.396
D81.7 Major histocompatibility complex class II deficiency
0.000 0.604 0.396
D81.6 Major histocompatibility complex class I deficiency
0.000 0.604 0.396
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.604 0.396
D81.4 Nezelof's syndrome
0.000 0.604 0.396
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.604 0.396
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.604 0.396
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.604 0.396
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.604 0.396
M05.88 Other seropositive rheumatoid arthritis (Other)
0.395 0.604 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.395 0.604 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.395 0.604 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.395 0.604 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.395 0.604 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.395 0.604 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.395 0.604 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.395 0.604 0.000
H36.0 Diabetic retinopathy
0.000 0.605 0.395
E06.9 Thyroiditis, unspecified
0.000 0.611 0.389
M08.9 Juvenile arthritis, unspecified
0.388 0.612 0.000
M08.8 Other juvenile arthritis
0.388 0.612 0.000
M08.4 Pauciarticular juvenile arthritis
0.388 0.612 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.388 0.612 0.000
M08.2 Juvenile arthritis with systemic onset
0.388 0.612 0.000
M08.1 Juvenile ankylosing spondylitis
0.388 0.612 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.614 0.386
E23 Hypofunction and other disorders of pituitary gland
0.000 0.614 0.386
M14.2 Diabetic arthropathy
0.381 0.618 0.000
L43 Lichen planus
0.370 0.619 0.011
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.622 0.378
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.622 0.378
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.622 0.378
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.622 0.378
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.622 0.378
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.622 0.378
E31.0 Autoimmune polyglandular failure
0.000 0.623 0.376
E07.8 Other specified disorders of thyroid
0.000 0.625 0.375
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.374 0.626 0.000
E28.3 Primary ovarian failure
0.000 0.628 0.372
E34.5 Androgen resistance syndrome
0.000 0.629 0.371
E34.4 Constitutional tall stature
0.000 0.629 0.371
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.629 0.371
E34.1 Other hypersecretion of intestinal hormones
0.000 0.629 0.371
D83.8 Other common variable immunodeficiencies
0.000 0.629 0.370
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.629 0.370
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.629 0.370
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.629 0.370
E61.1 Iron deficiency
0.000 0.629 0.370
M05.09 Felty's syndrome (Site unspecified)
0.370 0.630 0.000
M05.08 Felty's syndrome (Other)
0.370 0.630 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.370 0.630 0.000
M05.06 Felty's syndrome (Lower leg)
0.370 0.630 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.370 0.630 0.000
M05.04 Felty's syndrome (Hand)
0.370 0.630 0.000
M05.03 Felty's syndrome (Forearm)
0.370 0.630 0.000
M05.02 Felty's syndrome (Upper arm)
0.370 0.630 0.000
M05.01 Felty's syndrome (Shoulder region)
0.370 0.630 0.000
M05.00 Felty's syndrome (Multiple sites)
0.370 0.630 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.370 0.630 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.370 0.630 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.370 0.630 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.370 0.630 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.370 0.630 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.370 0.630 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.370 0.630 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.370 0.630 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.370 0.630 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.370 0.630 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.370 0.630 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.370 0.630 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.370 0.630 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.370 0.630 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.370 0.630 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.370 0.630 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.370 0.630 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.370 0.630 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.370 0.630 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.370 0.630 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.370 0.630 0.000
M09.0 Juvenile arthritis in psoriasis
0.370 0.630 0.000
M11.1 Familial chondrocalcinosis
0.368 0.632 0.000
M11.0 Hydroxyapatite deposition disease
0.368 0.632 0.000
E31.9 Polyglandular dysfunction, unspecified
0.000 0.634 0.366
E31.8 Other polyglandular dysfunction
0.000 0.634 0.366
E31.1 Polyglandular hyperfunction
0.000 0.634 0.366
H36 Retinal disorders in diseases classified elsewhere
0.000 0.639 0.360
E34.0 Carcinoid syndrome
0.000 0.641 0.359
E30.9 Disorder of puberty, unspecified
0.000 0.642 0.358
E30.8 Other disorders of puberty
0.000 0.642 0.358
E30.1 Precocious puberty
0.000 0.642 0.358
E30.0 Delayed puberty
0.000 0.642 0.358
E32.9 Disease of thymus, unspecified
0.000 0.642 0.358
E32.8 Other diseases of thymus
0.000 0.642 0.358
E32.1 Abscess of thymus
0.000 0.642 0.358
E32.0 Persistent hyperplasia of thymus
0.000 0.642 0.358
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.642 0.358
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.642 0.358
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.642 0.358
E34.3 Short stature, not elsewhere classified
0.000 0.644 0.356
L44.0 Pityriasis rubra pilaris
0.342 0.646 0.012
E29 Testicular dysfunction
0.000 0.647 0.353
M05.28 Rheumatoid vasculitis (Other)
0.352 0.647 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.352 0.647 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.352 0.647 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.352 0.647 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.352 0.647 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.352 0.647 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.352 0.647 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.352 0.647 0.000
M13 Other arthritis
0.352 0.648 0.000
M11.8 Other specified crystal arthropathies
0.351 0.648 0.000
C21.0 Anus, unspecified
0.351 0.649 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.650 0.350
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.348 0.652 0.000
C21.1 Anal canal
0.346 0.654 0.000
C21 Malignant neoplasm of anus and anal canal
0.343 0.657 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.657 0.343
M05.29 Rheumatoid vasculitis (Site unspecified)
0.341 0.659 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.340 0.659 0.000
M11.2 Other chondrocalcinosis
0.340 0.660 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.663 0.337
H04 Disorders of lachrymal system
0.000 0.664 0.336
E28.9 Ovarian dysfunction, unspecified
0.000 0.664 0.336
E28.8 Other ovarian dysfunction
0.000 0.664 0.336
E28.1 Androgen excess
0.000 0.664 0.336
E28.0 Oestrogen excess
0.000 0.664 0.336
H30-H36 Disorders of choroid and retina
0.000 0.664 0.336
D83.9 Common variable immunodeficiency, unspecified
0.000 0.665 0.335
L44.9 Papulosquamous disorder, unspecified
0.314 0.672 0.014
L44.8 Other specified papulosquamous disorders
0.314 0.672 0.014
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.314 0.672 0.014
L44.3 Lichen ruber moniliformis
0.314 0.672 0.014
L44.2 Lichen striatus
0.314 0.672 0.014
L44.1 Lichen nitidus
0.314 0.672 0.014
Chapter VII Diseases of the eye and adnexa
0.000 0.674 0.326
E04.9 Non-toxic goitre, unspecified
0.000 0.675 0.325
M11.96 Crystal arthropathy, unspecified (Lower leg)
0.324 0.676 0.000
D50-D53 Nutritional anaemias
0.000 0.676 0.324
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.677 0.323

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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