TreeWAS – Variant ID: rs9321490

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H50.9 Strabismus, unspecified	0.450	0.550	0.000
H50 Other strabismus	0.450	0.550	0.000
H50.0 Convergent concomitant strabismus	0.410	0.590	0.000
H50.1 Divergent concomitant strabismus	0.409	0.591	0.000
H50.2 Vertical strabismus	0.397	0.603	0.000
H50.5 Heterophoria	0.381	0.618	0.000
H50.6 Mechanical strabismus	0.364	0.636	0.000
H50.8 Other specified strabismus	0.358	0.642	0.000
H50.3 Intermittent heterotropia	0.322	0.677	0.000
H50.4 Other and unspecified heterotropia	0.315	0.685	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.220	0.780	0.000
H49 Paralytic strabismus	0.191	0.809	0.000
H51 Other disorders of binocular movement	0.167	0.833	0.000
H49.8 Other paralytic strabismus	0.163	0.837	0.000
H49.1 Fourth [trochlear] nerve palsy	0.153	0.847	0.000
H49.0 Third [oculomotor] nerve palsy	0.149	0.850	0.000
E03.9 Hypothyroidism, unspecified	0.138	0.862	0.000
H49.4 Progressive external ophthalmoplegia	0.137	0.863	0.000
H49.3 Total (external) ophthalmoplegia	0.137	0.863	0.000
H49.2 Sixth [abducent] nerve palsy	0.129	0.871	0.000
H51.2 Internuclear ophthalmoplegia	0.128	0.871	0.000
H49.9 Paralytic strabismus, unspecified	0.124	0.876	0.000
H51.9 Disorder of binocular movement, unspecified	0.120	0.880	0.000
H51.8 Other specified disorders of binocular movement	0.120	0.880	0.000
H51.1 Convergence insufficiency and excess	0.120	0.880	0.000
H51.0 Palsy of conjugate gaze	0.120	0.880	0.000
H52 Disorders of refraction and accommodation	0.102	0.898	0.000
E03 Other hypothyroidism	0.092	0.908	0.000
H52.7 Disorder of refraction, unspecified	0.084	0.916	0.000
H52.2 Astigmatism	0.081	0.919	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.075	0.925	0.000
H52.6 Other disorders of refraction	0.073	0.926	0.000
H52.5 Disorders of accommodation	0.073	0.926	0.000
H52.4 Presbyopia	0.073	0.926	0.000
E03.1 Congenital hypothyroidism without goitre	0.070	0.930	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.069	0.931	0.000
E03.8 Other specified hypothyroidism	0.069	0.931	0.000
E03.5 Myxoedema coma	0.066	0.934	0.000
E03.4 Atrophy of thyroid (acquired)	0.066	0.934	0.000
E03.3 Postinfectious hypothyroidism	0.066	0.934	0.000
H52.3 Anisometropia and aniseikonia	0.065	0.935	0.000
H52.0 Hypermetropia	0.052	0.947	0.000
H52.1 Myopia	0.022	0.978	0.000
E00-E07 Disorders of thyroid gland	0.022	0.978	0.000
Z36 Antenatal screening	0.000	0.979	0.021
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.979	0.021
Z36.8 Other antenatal screening	0.000	0.979	0.021
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.980	0.020
E05.9 Thyrotoxicosis, unspecified	0.019	0.981	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.019	0.981	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.018	0.982	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.982	0.018
Z36.9 Antenatal screening, unspecified	0.000	0.983	0.017
H05.0 Acute inflammation of orbit	0.017	0.983	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.984	0.016
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.016	0.984	0.000
E00 Congenital iodine-deficiency syndrome	0.016	0.984	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.985	0.015
H05 Disorders of orbit	0.015	0.985	0.000
E05.8 Other thyrotoxicosis	0.014	0.986	0.000
E05.5 Thyroid crisis or storm	0.014	0.986	0.000
E05.4 Thyrotoxicosis factitia	0.014	0.986	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.014	0.986	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.014	0.986	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.014	0.986	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.987	0.013
H05.8 Other disorders of orbit	0.013	0.987	0.000
E06 Thyroiditis	0.013	0.987	0.000
H05.2 Exophthalmic conditions	0.013	0.987	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.011	0.988	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.011	0.988	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.011	0.988	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.011	0.988	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.011	0.988	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.011	0.988	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.011	0.988	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.011	0.988	0.000
H05.9 Disorder of orbit, unspecified	0.011	0.989	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.011	0.989	0.000
H05.3 Deformity of orbit	0.011	0.989	0.000
H05.1 Chronic inflammatory disorders of orbit	0.011	0.989	0.000
H05.4 Enophthalmos	0.011	0.989	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.989	0.010
E06.5 Other chronic thyroiditis	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.010	0.990	0.000
E07 Other disorders of thyroid	0.010	0.990	0.000
E06.4 Drug-induced thyroiditis	0.009	0.991	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.009	0.991	0.000
E06.1 Subacute thyroiditis	0.009	0.991	0.000
E06.0 Acute thyroiditis	0.009	0.991	0.000
F31 Bipolar affective disorder	0.008	0.992	0.000
E06.9 Thyroiditis, unspecified	0.008	0.992	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.008	0.992	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.008	0.992	0.000
F31.9 Bipolar affective disorder, unspecified	0.008	0.992	0.000
H04.2 Epiphora	0.007	0.993	0.000
E07.1 Dyshormogenetic goitre	0.007	0.993	0.000
E07.0 Hypersecretion of calcitonin	0.007	0.993	0.000
J33.9 Nasal polyp, unspecified	0.007	0.993	0.000
F30 Manic episode	0.007	0.993	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.007	0.993	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.007	0.993	0.000
F30.2 Mania with psychotic symptoms	0.007	0.993	0.000
F31.7 Bipolar affective disorder, currently in remission	0.007	0.993	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.007	0.993	0.000
H06.2 Dysthyroid exophthalmos	0.007	0.993	0.000
F30.9 Manic episode, unspecified	0.007	0.993	0.000
Chapter VII Diseases of the eye and adnexa	0.007	0.993	0.000
F30-F39 Mood [affective] disorders	0.007	0.993	0.000
E07.8 Other specified disorders of thyroid	0.006	0.993	0.000
H04 Disorders of lachrymal system	0.006	0.994	0.000
E06.3 Autoimmune thyroiditis	0.006	0.994	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.006	0.994	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.006	0.994	0.000
F31.8 Other bipolar affective disorders	0.006	0.994	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.006	0.994	0.000
N39.3 Stress incontinence	0.000	0.994	0.006
F31.6 Bipolar affective disorder, current episode mixed	0.006	0.994	0.000
Y40.0 Penicillins	0.006	0.994	0.000
F30.0 Hypomania	0.006	0.994	0.000
F33 Recurrent depressive disorder	0.006	0.994	0.000
M47.1 Other spondylosis with myelopathy	0.006	0.994	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.006	0.994	0.000
H46 Optic neuritis	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.005	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.005	0.995	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.005	0.995	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.005	0.995	0.000
F30.8 Other manic episodes	0.005	0.995	0.000
F30.1 Mania without psychotic symptoms	0.005	0.995	0.000
H01 Other inflammation of eyelid	0.005	0.995	0.000
H01.0 Blepharitis	0.005	0.995	0.000
H00 Hordeolum and chalazion	0.005	0.995	0.000
H04.4 Chronic inflammation of lachrymal passages	0.005	0.995	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.995	0.005
H03 Disorders of eyelid in diseases classified elsewhere	0.005	0.995	0.000
C69.9 Eye, unspecified	0.005	0.995	0.000
F39 Unspecified mood [affective] disorder	0.005	0.995	0.000
H04.8 Other disorders of lachrymal system	0.005	0.995	0.000
Y40 Systemic antibiotics	0.005	0.995	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.005	0.995	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.005	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.005	0.995	0.000
F38 Other mood [affective] disorders	0.005	0.995	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.005	0.995	0.000
H04.6 Other changes in lachrymal passages	0.005	0.995	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.005	0.995	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.005	0.995	0.000
H04.0 Dacryoadenitis	0.005	0.995	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.005	0.995	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.005	0.995	0.000
N92.6 Irregular menstruation, unspecified	0.000	0.995	0.005
C71.9 Brain, unspecified	0.005	0.995	0.000
H47.3 Other disorders of optic disk	0.005	0.995	0.000
I47.1 Supraventricular tachycardia	0.005	0.995	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.005	0.995	0.000
R55 Syncope and collapse	0.005	0.995	0.000
Y40.4 Tetracyclines	0.005	0.995	0.000
C69 Malignant neoplasm of eye and adnexa	0.005	0.995	0.000
F33.9 Recurrent depressive disorder, unspecified	0.005	0.995	0.000
G40.9 Epilepsy, unspecified	0.005	0.995	0.000
F34 Persistent mood [affective] disorders	0.004	0.995	0.000
F33.8 Other recurrent depressive disorders	0.004	0.996	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.004	0.996	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.004	0.996	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.004	0.996	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.004	0.996	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.004	0.996	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.004	0.996	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.004	0.996	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.996	0.004
J46 Status asthmaticus	0.004	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.000	0.996	0.004
H55-H59 Other disorders of eye and adnexa	0.004	0.996	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.004	0.996	0.000
C69.0 Conjunctiva	0.004	0.996	0.000
B02.2 Zoster with other nervous system involvement	0.004	0.996	0.000
I47 Paroxysmal tachycardia	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.004	0.996	0.000
B02.9 Zoster without complication	0.004	0.996	0.000
C71.0 Cerebrum, except lobes and ventricles	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
H04.1 Other disorders of lachrymal gland	0.004	0.996	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.004	0.996	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.004	0.996	0.000
H04.9 Disorder of lachrymal system, unspecified	0.004	0.996	0.000
H01.1 Non-infectious dermatoses of eyelid	0.004	0.996	0.000
Y40.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
Y40.6 Rifamycins	0.004	0.996	0.000
Y40.2 Chloramphenicol group	0.004	0.996	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.004	0.996	0.000
H47.7 Disorder of visual pathways, unspecified	0.004	0.996	0.000
H47.6 Disorders of visual cortex	0.004	0.996	0.000
H47.5 Disorders of other visual pathways	0.004	0.996	0.000
H47.4 Disorders of optic chiasm	0.004	0.996	0.000
E04 Other non-toxic goitre	0.004	0.996	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.004	0.996	0.000
F38.8 Other specified mood [affective] disorders	0.004	0.996	0.000
F38.1 Other recurrent mood [affective] disorders	0.004	0.996	0.000
F38.0 Other single mood [affective] disorders	0.004	0.996	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
H10-H13 Disorders of conjunctiva	0.003	0.996	0.000
H47.1 Papilloedema, unspecified	0.004	0.996	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.004	0.996	0.000
Y40.5 Aminoglycosides	0.004	0.996	0.000
C69.3 Choroid	0.004	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.004	0.996	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.004	0.996	0.000
M96.5 Postradiation scoliosis	0.004	0.996	0.000
M96.4 Postsurgical lordosis	0.004	0.996	0.000
M96.3 Postlaminectomy kyphosis	0.004	0.996	0.000
M96.2 Postradiation kyphosis	0.004	0.996	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
B02 Zoster [herpes zoster]	0.004	0.996	0.000
H47.2 Optic atrophy	0.004	0.996	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.003	0.996	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.003	0.996	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.003	0.996	0.000
C69.8 Overlapping lesion of eye and adnexa	0.003	0.996	0.000
C69.6 Orbit	0.003	0.996	0.000
C69.5 Lachrymal gland and duct	0.003	0.996	0.000
C69.4 Ciliary body	0.003	0.996	0.000
C69.2 Retina	0.003	0.996	0.000
C69.1 Cornea	0.003	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.996	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.996	0.000
F34.0 Cyclothymia	0.003	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
K86 Other diseases of pancreas	0.000	0.996	0.004
N71.1 Chronic inflammatory disease of uterus	0.004	0.996	0.000
G50.0 Trigeminal neuralgia	0.004	0.996	0.000
K86.3 Pseudocyst of pancreas	0.000	0.996	0.004
Y40.3 Macrolides	0.003	0.996	0.000
C71.1 Frontal lobe	0.003	0.996	0.000
K86.1 Other chronic pancreatitis	0.000	0.996	0.004
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
I47.0 Reentry ventricular arrhythmia	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
B02.8 Zoster with other complications	0.003	0.997	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
E11.4 With neurological complications	0.003	0.997	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.003	0.997	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.003	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
F34.1 Dysthymia	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.003	0.997	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
H01.9 Inflammation of eyelid, unspecified	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
G40 Epilepsy	0.003	0.997	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.003	0.997	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.003	0.997	0.000
E04.8 Other specified non-toxic goitre	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
C70 Malignant neoplasm of meninges	0.003	0.997	0.000
H43-H45 Disorders of vitreous body and globe	0.003	0.997	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.003	0.997	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.003	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
J33 Nasal polyp	0.003	0.997	0.000
B02.7 Disseminated zoster	0.003	0.997	0.000
B02.1 Zoster meningitis	0.003	0.997	0.000
B02.0 Zoster encephalitis	0.003	0.997	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
H40-H42 Glaucoma	0.003	0.997	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
F25 Schizoaffective disorders	0.003	0.997	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
B02.3 Zoster ocular disease	0.003	0.997	0.000
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
F25.1 Schizoaffective disorder, depressive type	0.003	0.997	0.000
L92.0 Granuloma annulare	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.003	0.997	0.000
H01.8 Other specified inflammation of eyelid	0.002	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
H11 Other disorders of conjunctiva	0.002	0.997	0.001
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
F20 Schizophrenia	0.003	0.997	0.000
H59.0 Vitreous syndrome following cataract surgery	0.002	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.997	0.000
E27.0 Other adrenocortical overactivity	0.002	0.997	0.000
G40.8 Other epilepsy	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
F29 Unspecified nonorganic psychosis	0.003	0.997	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
H13.3 Ocular pemphigoid	0.002	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.997	0.000
M99 Biomechanical lesions, not elsewhere classified	0.002	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.997	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.002	0.997	0.000
F20.8 Other schizophrenia	0.002	0.997	0.000
J33.8 Other polyp of sinus	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.997	0.000
E42 Marasmic kwashiorkor	0.002	0.997	0.000
E41 Nutritional marasmus	0.002	0.997	0.000
E40 Kwashiorkor	0.002	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.997	0.000
M46.4 Discitis, unspecified	0.002	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
Y53.7 Emetics	0.002	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.997	0.000
Y53.5 Digestants	0.002	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y53.2 Stimulant laxatives	0.002	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.997	0.000
F23 Acute and transient psychotic disorders	0.002	0.997	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.997	0.000
E24.8 Other Cushing's syndrome	0.002	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.997	0.000
E24.1 Nelson's syndrome	0.002	0.997	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.002	0.997	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.002	0.997	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.002	0.997	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H13.0 Filarial infection of conjunctiva	0.002	0.997	0.000
E11.2 With renal complications	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
G40.5 Special epileptic syndromes	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
H53 Visual disturbances	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.002	0.998	0.000
C70.1 Spinal meninges	0.002	0.998	0.000
C70.0 Cerebral meninges	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
C72.9 Central nervous system, unspecified	0.002	0.998	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.998	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.998	0.000
C72.4 Acoustic nerve	0.002	0.998	0.000
C72.3 Optic nerve	0.002	0.998	0.000
C72.2 Olfactory nerve	0.002	0.998	0.000
C72.1 Cauda equina	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
C72.0 Spinal cord	0.002	0.998	0.000
E14.9 Without complications	0.002	0.998	0.000
J33.1 Polypoid sinus degeneration	0.002	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.002	0.998	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
H10 Conjunctivitis	0.002	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
H42 Glaucoma in diseases classified elsewhere	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
H00.1 Chalazion	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M99.71 Connective tissue and disc stenosis of intervertebral foramina (Cervical region)	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.998	0.000
E16.3 Increased secretion of glucagon	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
E11 Non-insulin-dependent diabetes mellitus	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
H11.1 Conjunctival degenerations and deposits	0.002	0.998	0.000
M46.42 Discitis, unspecified (Cervical region)	0.002	0.998	0.000
E11.8 With unspecified complications	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.002	0.998	0.000
F24 Induced delusional disorder	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations