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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9488238
log Bayes Factor = 2.8638
Chromosome 6   position 114,017,133  (GRCh37) Explore rs9488238 on Ensembl!
Variant rs9488238 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
I60-I69 Cerebrovascular diseases
0.992 0.008 0.000
I42 Cardiomyopathy
0.980 0.020 0.000
I50 Heart failure
0.979 0.021 0.000
I50.1 Left ventricular failure
0.967 0.033 0.000
I44 Atrioventricular and left bundle-branch block
0.961 0.039 0.000
I69 Sequelae of cerebrovascular disease
0.949 0.051 0.000
I05-I09 Chronic rheumatic heart diseases
0.932 0.068 0.000
I47 Paroxysmal tachycardia
0.927 0.073 0.000
I42.9 Cardiomyopathy, unspecified
0.914 0.086 0.000
Chapter VII Diseases of the eye and adnexa
0.904 0.096 0.000
I42.0 Dilated cardiomyopathy
0.902 0.098 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.898 0.102 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.895 0.105 0.000
H43-H45 Disorders of vitreous body and globe
0.881 0.119 0.000
# Top node
0.879 0.121 0.000
I61 Intracerebral haemorrhage
0.871 0.129 0.000
I07 Rheumatic tricuspid valve diseases
0.870 0.130 0.000
E10-E14 Diabetes mellitus
0.866 0.134 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.864 0.136 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.862 0.138 0.000
H43 Disorders of vitreous body
0.862 0.138 0.000
I44.0 Atrioventricular block, first degree
0.859 0.141 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.858 0.142 0.000
E14 Unspecified diabetes mellitus
0.843 0.157 0.000
H43.1 Vitreous haemorrhage
0.842 0.158 0.000
H55-H59 Other disorders of eye and adnexa
0.840 0.160 0.000
E10 Insulin-dependent diabetes mellitus
0.839 0.161 0.000
I44.7 Left bundle-branch block, unspecified
0.836 0.164 0.000
E14.9 Without complications
0.833 0.167 0.000
I60 Subarachnoid haemorrhage
0.830 0.170 0.000
I47.2 Ventricular tachycardia
0.829 0.171 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.827 0.173 0.000
I07.1 Tricuspid insufficiency
0.826 0.174 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.823 0.177 0.000
I62 Other nontraumatic intracranial haemorrhage
0.822 0.178 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.820 0.180 0.000
E10.9 Without complications
0.819 0.181 0.000
I47.1 Supraventricular tachycardia
0.818 0.182 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.812 0.188 0.000
I73 Other peripheral vascular diseases
0.811 0.189 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.808 0.192 0.000
I27 Other pulmonary heart diseases
0.802 0.198 0.000
I44.6 Other and unspecified fascicular block
0.793 0.207 0.000
I63 Cerebral infarction
0.792 0.208 0.000
I45 Other conduction disorders
0.789 0.211 0.000
I51 Complications and ill-defined descriptions of heart disease
0.788 0.212 0.000
E11 Non-insulin-dependent diabetes mellitus
0.786 0.214 0.000
I50.0 Congestive heart failure
0.776 0.224 0.000
I44.3 Other and unspecified atrioventricular block
0.774 0.226 0.000
H57 Other disorders of eye and adnexa
0.772 0.228 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.771 0.229 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.766 0.234 0.000
H52 Disorders of refraction and accommodation
0.765 0.235 0.000
I73.9 Peripheral vascular disease, unspecified
0.765 0.235 0.000
Chapter V Mental and behavioural disorders
0.758 0.242 0.000
I42.2 Other hypertrophic cardiomyopathy
0.755 0.245 0.000
I67 Other cerebrovascular diseases
0.754 0.246 0.000
I31 Other diseases of pericardium
0.751 0.249 0.000
H02 Other disorders of eyelid
0.749 0.251 0.000
I70 Atherosclerosis
0.748 0.252 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.747 0.252 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.746 0.254 0.000
I27.0 Primary pulmonary hypertension
0.745 0.255 0.000
I08 Multiple valve diseases
0.741 0.259 0.000
I35 Nonrheumatic aortic valve disorders
0.736 0.264 0.000
Chapter I Certain infectious and parasitic diseases
0.734 0.266 0.000
I36 Nonrheumatic tricuspid valve disorders
0.729 0.271 0.000
H10-H13 Disorders of conjunctiva
0.727 0.273 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.726 0.274 0.000
H00 Hordeolum and chalazion
0.724 0.276 0.000
I42.8 Other cardiomyopathies
0.723 0.276 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.719 0.281 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.714 0.286 0.000
H02.3 Blepharochalasis
0.713 0.287 0.000
I72 Other aneurysm
0.713 0.287 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.288 0.000
I33 Acute and subacute endocarditis
0.710 0.290 0.000
I30 Acute pericarditis
0.710 0.290 0.000
E11.5 With peripheral circulatory complications
0.709 0.291 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.704 0.296 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.702 0.298 0.000
I42.6 Alcoholic cardiomyopathy
0.702 0.298 0.000
I42.5 Other restrictive cardiomyopathy
0.702 0.298 0.000
I42.4 Endocardial fibroelastosis
0.702 0.298 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.702 0.298 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.702 0.298 0.000
F30-F39 Mood [affective] disorders
0.701 0.299 0.000
B35-B49 Mycoses
0.697 0.303 0.000
I63.9 Cerebral infarction, unspecified
0.697 0.303 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.694 0.306 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.692 0.308 0.000
H43.3 Other vitreous opacities
0.691 0.309 0.000
H55 Nystagmus and other irregular eye movements
0.691 0.309 0.000
H25-H28 Disorders of lens
0.690 0.310 0.000
I44.5 Left posterior fascicular block
0.689 0.311 0.000
I44.4 Left anterior fascicular block
0.689 0.311 0.000
H04 Disorders of lachrymal system
0.688 0.312 0.000
H18 Other disorders of cornea
0.687 0.313 0.000
H57.8 Other specified disorders of eye and adnexa
0.684 0.316 0.000
Chapter X Diseases of the respiratory system
0.682 0.318 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.681 0.319 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.681 0.319 0.000
H53-H54 Visual disturbances and blindness
0.680 0.320 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.678 0.322 0.000
F33 Recurrent depressive disorder
0.677 0.323 0.000
H49 Paralytic strabismus
0.676 0.324 0.000
I68.0 Cerebral amyloid angiopathy
0.676 0.324 0.000
S80-S89 Injuries to the knee and lower leg
0.674 0.326 0.000
H44 Disorders of globe
0.674 0.326 0.000
I09 Other rheumatic heart diseases
0.668 0.331 0.000
I06 Rheumatic aortic valve diseases
0.668 0.331 0.000
S32 Fracture of lumbar spine and pelvis
0.668 0.332 0.000
H17 Corneal scars and opacities
0.666 0.334 0.000
I47.0 Reentry ventricular arrhythmia
0.664 0.335 0.000
T79-T79 Certain early complications of trauma
0.664 0.336 0.000
I44.2 Atrioventricular block, complete
0.663 0.337 0.000
I60.8 Other subarachnoid haemorrhage
0.661 0.339 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.661 0.339 0.000
F99-F99 Unspecified mental disorder
0.660 0.340 0.000
I05 Rheumatic mitral valve diseases
0.659 0.340 0.000
Chapter XXII Codes for special purposes
0.659 0.341 0.000
H05 Disorders of orbit
0.658 0.342 0.000
I77 Other disorders of arteries and arterioles
0.658 0.342 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.657 0.343 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.656 0.344 0.000
I27.2 Other secondary pulmonary hypertension
0.656 0.344 0.000
H52.3 Anisometropia and aniseikonia
0.655 0.345 0.000
I95 Hypotension
0.655 0.345 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.654 0.346 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.654 0.346 0.000
B37 Candidiasis
0.649 0.351 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.648 0.352 0.000
S82 Fracture of lower leg, including ankle
0.648 0.352 0.000
I69.3 Sequelae of cerebral infarction
0.647 0.353 0.000
I71 Aortic aneurysm and dissection
0.647 0.353 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.645 0.355 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.644 0.356 0.000
E11.3 With ophthalmic complications
0.644 0.356 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.643 0.357 0.000
I99 Other and unspecified disorders of circulatory system
0.641 0.359 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.640 0.360 0.000
E20-E35 Disorders of other endocrine glands
0.639 0.361 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.636 0.364 0.000
I49 Other cardiac arrhythmias
0.636 0.364 0.000
F33.9 Recurrent depressive disorder, unspecified
0.635 0.364 0.000
H16 Keratitis
0.633 0.367 0.000
T91 Sequelae of injuries of neck and trunk
0.633 0.367 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.632 0.368 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.632 0.368 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.630 0.370 0.000
H02.4 Ptosis of eyelid
0.629 0.371 0.000
I45.1 Other and unspecified right bundle-branch block
0.628 0.372 0.000
H52.2 Astigmatism
0.628 0.372 0.000
J40-J47 Chronic lower respiratory diseases
0.627 0.373 0.000
I45.9 Conduction disorder, unspecified
0.627 0.373 0.000
E10.3 With ophthalmic complications
0.626 0.374 0.000
I44.1 Atrioventricular block, second degree
0.625 0.375 0.000
I61.8 Other intracerebral haemorrhage
0.625 0.375 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.625 0.375 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.625 0.375 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.625 0.375 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.625 0.375 0.000
H57.1 Ocular pain
0.625 0.375 0.000
I07.9 Tricuspid valve disease, unspecified
0.624 0.376 0.000
I07.8 Other tricuspid valve diseases
0.624 0.376 0.000
I07.2 Tricuspid stenosis with insufficiency
0.624 0.376 0.000
I07.0 Tricuspid stenosis
0.624 0.376 0.000
T66-T78 Other and unspecified effects of external causes
0.623 0.377 0.000
S82.6 Fracture of lateral malleolus
0.623 0.377 0.000
S70-S79 Injuries to the hip and thigh
0.622 0.378 0.000
E12 Malnutrition-related diabetes mellitus
0.621 0.379 0.000
I28 Other diseases of pulmonary vessels
0.619 0.381 0.000
E11.9 Without complications
0.619 0.381 0.000
H43.9 Disorder of vitreous body, unspecified
0.618 0.382 0.000
H43.2 Crystalline deposits in vitreous body
0.618 0.382 0.000
H43.0 Vitreous prolapse
0.618 0.382 0.000
S10-S19 Injuries to the neck
0.618 0.382 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.615 0.384 0.000
T93 Sequelae of injuries of lower limb
0.615 0.385 0.000
H52.0 Hypermetropia
0.615 0.385 0.000
E40-E46 Malnutrition
0.615 0.385 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.613 0.387 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.612 0.388 0.000
I51.9 Heart disease, unspecified
0.611 0.389 0.000
E10.2 With renal complications
0.610 0.389 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.610 0.390 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.609 0.391 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.609 0.391 0.000
S90-S99 Injuries to the ankle and foot
0.607 0.393 0.000
H43.8 Other disorders of vitreous body
0.607 0.393 0.000
S82.60 Fracture of lateral malleolus (closed)
0.606 0.394 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.606 0.394 0.000
I67.1 Cerebral aneurysm, nonruptured
0.605 0.395 0.000
J44 Other chronic obstructive pulmonary disease
0.605 0.395 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.605 0.395 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.605 0.395 0.000
E14.8 With unspecified complications
0.604 0.396 0.000
E14.7 With multiple complications
0.604 0.396 0.000
E14.6 With other specified complications
0.604 0.396 0.000
E14.5 With peripheral circulatory complications
0.604 0.396 0.000
E14.4 With neurological complications
0.604 0.396 0.000
E14.2 Withrenal complications
0.604 0.396 0.000
E14.1 With ketoacidosis
0.604 0.396 0.000
E14.0 With coma
0.604 0.396 0.000
E13 Other specified diabetes mellitus
0.603 0.397 0.000
I46 Cardiac arrest
0.601 0.399 0.000
E10.8 With unspecified complications
0.601 0.399 0.000
E10.7 With multiple complications
0.601 0.399 0.000
E10.6 With other specified complications
0.601 0.399 0.000
E10.5 With peripheral circulatory complications
0.601 0.399 0.000
E10.4 With neurological complications
0.601 0.399 0.000
E10.0 With coma
0.601 0.399 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.601 0.399 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.601 0.399 0.000
H01 Other inflammation of eyelid
0.601 0.399 0.000
I31.3 Pericardial effusion (noninflammatory)
0.599 0.400 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.598 0.402 0.000
H21 Other disorders of iris and ciliary body
0.596 0.404 0.000
E11.6 With other specified complications
0.596 0.404 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.595 0.405 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.595 0.405 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.595 0.405 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.595 0.405 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.595 0.405 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.595 0.405 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.595 0.405 0.000
I51.0 Cardiac septal defect, acquired
0.594 0.406 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.594 0.406 0.000
T33-T35 Frostbite
0.593 0.407 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.593 0.407 0.000
T00-T07 Injuries involving multiple body regions
0.593 0.407 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.592 0.408 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.590 0.410 0.000
I62.1 Nontraumatic extradural haemorrhage
0.589 0.410 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.589 0.411 0.000
F99 Mental disorder, not otherwise specified
0.589 0.411 0.000
F60-F69 Disorders of adult personality and behaviour
0.588 0.412 0.000
H52.1 Myopia
0.588 0.412 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.588 0.412 0.000
H51 Other disorders of binocular movement
0.588 0.412 0.000
B99-B99 Other infectious diseases
0.586 0.414 0.000
I08.8 Other multiple valve diseases
0.585 0.415 0.000
B37.0 Candidal stomatitis
0.583 0.417 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.582 0.418 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.582 0.418 0.000
H15 Disorders of sclera
0.582 0.418 0.000
I73.8 Other specified peripheral vascular diseases
0.582 0.418 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.582 0.418 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.581 0.419 0.000
I70.0 Atherosclerosis of aorta
0.580 0.420 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.579 0.420 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.579 0.420 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.579 0.420 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.577 0.423 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.577 0.423 0.000
E27 Other disorders of adrenal gland
0.576 0.424 0.000
I27.8 Other specified pulmonary heart diseases
0.575 0.425 0.000
I27.1 Kyphoscoliotic heart disease
0.575 0.425 0.000
M40-M43 Deforming dorsopathies
0.574 0.425 0.000
I67.9 Cerebrovascular disease, unspecified
0.574 0.426 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.574 0.426 0.000
I51.7 Cardiomegaly
0.574 0.426 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.573 0.427 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.572 0.428 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.570 0.430 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.568 0.432 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.568 0.432 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.568 0.432 0.000
J40 Bronchitis, not specified as acute or chronic
0.568 0.432 0.000
H10 Conjunctivitis
0.567 0.433 0.000
J95-J99 Other diseases of the respiratory system
0.566 0.434 0.000
I45.8 Other specified conduction disorders
0.566 0.434 0.000
I45.4 Nonspecific intraventricular block
0.566 0.434 0.000
I45.3 Trifascicular block
0.566 0.434 0.000
I45.2 Bifascicular block
0.566 0.434 0.000
I45.0 Right fascicular block
0.566 0.434 0.000
M80-M85 Disorders of bone density and structure
0.565 0.435 0.000
I51.6 Cardiovascular disease, unspecified
0.565 0.435 0.000
I51.5 Myocardial degeneration
0.565 0.435 0.000
I51.4 Myocarditis, unspecified
0.565 0.435 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.565 0.435 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.565 0.435 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.565 0.435 0.000
E10.1 With ketoacidosis
0.565 0.435 0.000
H11 Other disorders of conjunctiva
0.564 0.436 0.000
E11.8 With unspecified complications
0.564 0.436 0.000
E11.7 With multiple complications
0.564 0.436 0.000
E11.0 With coma
0.564 0.436 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.564 0.436 0.000
S32.5 Fracture of pubis
0.563 0.437 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.563 0.437 0.000
I51.8 Other ill-defined heart diseases
0.563 0.437 0.000
H17.9 Corneal scar and opacity, unspecified
0.562 0.438 0.000
H04.1 Other disorders of lachrymal gland
0.561 0.439 0.000
H46 Optic neuritis
0.561 0.439 0.000
E50-E64 Other nutritional deficiencies
0.561 0.439 0.000
I74 Arterial embolism and thrombosis
0.560 0.440 0.000
H27 Other disorders of lens
0.559 0.441 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.559 0.441 0.000
B35 Dermatophytosis
0.558 0.441 0.000
H02.6 Xanthelasma of eyelid
0.558 0.442 0.000
I95.9 Hypotension, unspecified
0.558 0.442 0.000
I20-I25 Ischaemic heart diseases
0.555 0.445 0.000
H00.1 Chalazion
0.554 0.446 0.000
I45.5 Other specified heart block
0.553 0.447 0.000
H57.0 Anomalies of pupillary function
0.553 0.447 0.000
H18.4 Corneal degeneration
0.553 0.447 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.552 0.448 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.552 0.448 0.000
M85 Other disorders of bone density and structure
0.550 0.450 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.549 0.450 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.549 0.450 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.549 0.450 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.549 0.450 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.549 0.450 0.000
T36 Poisoning by systemic antibiotics
0.549 0.450 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.549 0.451 0.000
H18.6 Keratoconus
0.549 0.451 0.000
H52.7 Disorder of refraction, unspecified
0.548 0.451 0.000
H52.6 Other disorders of refraction
0.548 0.451 0.000
H52.5 Disorders of accommodation
0.548 0.451 0.000
H52.4 Presbyopia
0.548 0.451 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.548 0.452 0.000
I72.3 Aneurysm of iliac artery
0.547 0.452 0.000
H02.9 Disorder of eyelid, unspecified
0.547 0.453 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.547 0.453 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.547 0.453 0.000
S32.4 Fracture of acetabulum
0.547 0.453 0.000
E11.1 With ketoacidosis
0.547 0.453 0.000
F80-F89 Disorders of psychological development
0.547 0.453 0.000
H20 Iridocyclitis
0.546 0.454 0.000
H54 Blindness and low vision
0.544 0.455 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.544 0.456 0.000
H49.1 Fourth [trochlear] nerve palsy
0.544 0.456 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.544 0.456 0.000
F70-F79 Mental retardation
0.544 0.456 0.000
I38 Endocarditis, valve unspecified
0.543 0.456 0.000
I35.0 Aortic (valve) stenosis
0.542 0.458 0.000
B15-B19 Viral hepatitis
0.541 0.459 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.541 0.459 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.541 0.459 0.000
I67.5 Moyamoya disease
0.541 0.459 0.000
I67.4 Hypertensive encephalopathy
0.541 0.459 0.000
I67.3 Progressive vascular leukoencephalopathy
0.541 0.459 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.541 0.459 0.000
I31.8 Other specified diseases of pericardium
0.539 0.461 0.000
I31.2 Haemopericardium, not elsewhere classified
0.539 0.461 0.000
I31.1 Chronic constrictive pericarditis
0.539 0.461 0.000
I31.0 Chronic adhesive pericarditis
0.539 0.461 0.000
I08.0 Disorders of both mitral and aortic valves
0.539 0.461 0.000
I35.9 Aortic valve disorder, unspecified
0.538 0.462 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.537 0.463 0.000
H02.2 Lagophthalmos
0.537 0.463 0.000
I70.9 Generalised and unspecified atherosclerosis
0.537 0.463 0.000
I70.8 Atherosclerosis of other arteries
0.537 0.463 0.000
I70.1 Atherosclerosis of renal artery
0.537 0.463 0.000
M85.8 Other specified disorders of bone density and structure
0.536 0.464 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.535 0.464 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.535 0.465 0.000
S37 Injury of urinary and pelvic organs
0.535 0.465 0.000
S36 Injury of intra-abdominal organs
0.535 0.465 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.535 0.465 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.535 0.465 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.535 0.465 0.000
S31 Open wound of abdomen, lower back and pelvis
0.535 0.465 0.000
J43 Emphysema
0.535 0.465 0.000
I72.8 Aneurysm of other specified arteries
0.535 0.465 0.000
H04.4 Chronic inflammation of lachrymal passages
0.534 0.466 0.000
H04.2 Epiphora
0.534 0.466 0.000
I34 Nonrheumatic mitral valve disorders
0.533 0.467 0.000
I24 Other acute ischaemic heart diseases
0.533 0.467 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.532 0.468 0.000
I08.9 Multiple valve disease, unspecified
0.532 0.468 0.000
I67.2 Cerebral atherosclerosis
0.529 0.471 0.000
H49.0 Third [oculomotor] nerve palsy
0.529 0.471 0.000
I27.9 Pulmonary heart disease, unspecified
0.529 0.471 0.000
H02.5 Other disorders affecting eyelid function
0.528 0.472 0.000
I49.1 Atrial premature depolarisation
0.528 0.472 0.000
I72.4 Aneurysm of artery of lower extremity
0.528 0.472 0.000
I35.8 Other aortic valve disorders
0.528 0.472 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.526 0.473 0.000
B65-B83 Helminthiases
0.526 0.473 0.000
B50-B64 Protozoal diseases
0.526 0.473 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.526 0.473 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.526 0.473 0.000
A75-A79 Rickettsioses
0.526 0.473 0.000
A70-A74 Other diseases caused by chlamydiae
0.526 0.473 0.000
A65-A69 Other spirochaetal diseases
0.526 0.473 0.000
A20-A28 Certain zoonotic bacterial diseases
0.526 0.473 0.000
A15-A19 Tuberculosis
0.526 0.473 0.000
A80-A89 Viral infections of the central nervous system
0.526 0.474 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.526 0.474 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.526 0.474 0.000
B44 Aspergillosis
0.525 0.475 0.000
E11.2 With renal complications
0.525 0.475 0.000
T98 Sequelae of other and unspecified effects of external causes
0.524 0.476 0.000
S71 Open wound of hip and thigh
0.524 0.476 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.523 0.477 0.000
B49 Unspecified mycosis
0.523 0.477 0.000
M43 Other deforming dorsopathies
0.523 0.477 0.000
I95.0 Idiopathic hypotension
0.523 0.477 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.522 0.477 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.522 0.477 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.522 0.477 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.522 0.477 0.000
T92 Sequelae of injuries of upper limb
0.522 0.478 0.000
B37.8 Candidiasis of other sites
0.522 0.478 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.521 0.478 0.000
A30-A49 Other bacterial diseases
0.521 0.479 0.000
I95.8 Other hypotension
0.521 0.479 0.000
T95 Sequelae of burns, corrosions and frostbite
0.520 0.480 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.520 0.480 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.520 0.480 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.520 0.480 0.000
F30 Manic episode
0.520 0.480 0.000
J90-J94 Other diseases of pleura
0.520 0.480 0.000
I45.6 Preexcitation syndrome
0.519 0.481 0.000
S86 Injury of muscle and tendon at lower leg level
0.519 0.481 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.518 0.482 0.000
T91.3 Sequelae of injury of spinal cord
0.518 0.482 0.000
I24.8 Other forms of acute ischaemic heart disease
0.517 0.483 0.000
I77.0 Arteriovenous fistula, acquired
0.517 0.483 0.000
J30-J39 Other diseases of upper respiratory tract
0.517 0.483 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.517 0.483 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.517 0.483 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.516 0.483 0.000
I77.1 Stricture of artery
0.517 0.483 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.516 0.484 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.516 0.484 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.515 0.485 0.000
S20-S29 Injuries to the thorax
0.515 0.485 0.000
B37.4 Candidiasis of other urogenital sites
0.514 0.486 0.000
I78 Diseases of capillaries
0.514 0.486 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.513 0.487 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.513 0.487 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.513 0.487 0.000
I37.9 Pulmonary valve disorder, unspecified
0.513 0.487 0.000
I37.8 Other pulmonary valve disorders
0.513 0.487 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.513 0.487 0.000
I37.1 Pulmonary valve insufficiency
0.513 0.487 0.000
I37.0 Pulmonary valve stenosis
0.513 0.487 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.513 0.487 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.513 0.487 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.513 0.487 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.513 0.487 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.513 0.487 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.513 0.487 0.000
I40.9 Acute myocarditis, unspecified
0.513 0.487 0.000
I40.8 Other acute myocarditis
0.513 0.487 0.000
I40.1 Isolated myocarditis
0.513 0.487 0.000
I40.0 Infective myocarditis
0.513 0.487 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.513 0.487 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.513 0.487 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.513 0.487 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.513 0.487 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.513 0.487 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.513 0.487 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.513 0.487 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.513 0.487 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.513 0.487 0.000
I48.4 Atypical atrial flutter
0.513 0.487 0.000
I48.3 Typical atrial flutter
0.513 0.487 0.000
I48.2 Chronic atrial fibrillation
0.513 0.487 0.000
I48.1 Persistent atrial fibrillation
0.513 0.487 0.000
I48.0 Paroxysmal atrial fibrillation
0.513 0.487 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.513 0.487 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.513 0.487 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.513 0.487 0.000
I02 Rheumatic chorea
0.513 0.487 0.000
I01 Rheumatic fever with heart involvement
0.513 0.487 0.000
I00 Rheumatic fever without mention of heart involvement
0.513 0.487 0.000
H44.0 Purulent endophthalmitis
0.512 0.488 0.000
I72.9 Aneurysm of unspecified site
0.511 0.489 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.511 0.489 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.511 0.489 0.000
I72.2 Aneurysm of renal artery
0.511 0.489 0.000
I72.1 Aneurysm of artery of upper extremity
0.511 0.489 0.000
I72.0 Aneurysm of carotid artery
0.511 0.489 0.000
H05.0 Acute inflammation of orbit
0.511 0.489 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.510 0.490 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.510 0.490 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.510 0.490 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.510 0.490 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.510 0.490 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.510 0.490 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.510 0.490 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.510 0.490 0.000
H02.0 Entropion and trichiasis of eyelid
0.509 0.490 0.000
I33.9 Acute endocarditis, unspecified
0.509 0.491 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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