TreeWAS – Variant ID: rs9500924

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.1 With ketoacidosis	0.996	0.004	0.000
E10.4 With neurological complications	0.952	0.048	0.000
E10.5 With peripheral circulatory complications	0.924	0.076	0.000
E10.8 With unspecified complications	0.874	0.126	0.000
E10.2 With renal complications	0.873	0.127	0.000
E10.6 With other specified complications	0.783	0.217	0.000
E10.0 With coma	0.772	0.228	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E10-E14 Diabetes mellitus	0.432	0.568	0.000
E12 Malnutrition-related diabetes mellitus	0.310	0.690	0.000
E11 Non-insulin-dependent diabetes mellitus	0.294	0.706	0.000
E13 Other specified diabetes mellitus	0.288	0.712	0.000
E11.3 With ophthalmic complications	0.273	0.727	0.000
E14 Unspecified diabetes mellitus	0.261	0.739	0.000
E11.5 With peripheral circulatory complications	0.252	0.748	0.000
K90.0 Coeliac disease	0.000	0.758	0.242
M20-M25 Other joint disorders	0.236	0.764	0.000
M21 Other acquired deformities of limbs	0.235	0.765	0.000
H36.0 Diabetic retinopathy	0.234	0.766	0.000
M21.1 Varus deformity, not elsewhere classified	0.231	0.769	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.230	0.770	0.000
E11.1 With ketoacidosis	0.228	0.772	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.227	0.773	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.225	0.775	0.000
E14.8 With unspecified complications	0.223	0.777	0.000
M22 Disorders of patella	0.223	0.777	0.000
E12.9 Without complications	0.222	0.777	0.000
E12.8 With unspecified complications	0.222	0.777	0.000
E12.7 With multiple complications	0.222	0.777	0.000
E12.6 With other specified complications	0.222	0.777	0.000
E12.5 With peripheral circulatory complications	0.222	0.777	0.000
E12.4 With neurological complications	0.222	0.777	0.000
E12.3 With ophthalmic complications	0.222	0.777	0.000
E12.2 With renal complications	0.222	0.777	0.000
E12.1 With ketoacidosis	0.222	0.777	0.000
E12.0 With coma	0.222	0.777	0.000
E11.6 With other specified complications	0.222	0.778	0.000
M25 Other joint disorders, not elsewhere classified	0.222	0.778	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.221	0.779	0.000
S60-S69 Injuries to the wrist and hand	0.220	0.780	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.214	0.786	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.214	0.786	0.000
M25.5 Pain in joint	0.213	0.787	0.000
S68 Traumatic amputation of wrist and hand	0.211	0.789	0.000
E11.7 With multiple complications	0.211	0.789	0.000
M25.51 Pain in joint (Shoulder region)	0.209	0.791	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.208	0.792	0.000
E13.8 With unspecified complications	0.207	0.793	0.000
E13.7 With multiple complications	0.207	0.793	0.000
E13.6 With other specified complications	0.207	0.793	0.000
E13.5 With peripheral circulatory complications	0.207	0.793	0.000
E13.4 With neurological complications	0.207	0.793	0.000
E13.3 With ophthalmic complications	0.207	0.793	0.000
E13.2 With renal complications	0.207	0.793	0.000
E13.1 With ketoacidosis	0.207	0.793	0.000
E13.0 With coma	0.207	0.793	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.206	0.794	0.000
E11.0 With coma	0.205	0.794	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.205	0.795	0.000
M22.4 Chondromalacia patellae	0.205	0.795	0.000
M86-M90 Other osteopathies	0.202	0.798	0.000
M35 Other systemic involvement of connective tissue	0.201	0.799	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.201	0.799	0.000
M91-M94 Chondropathies	0.201	0.799	0.000
H36 Retinal disorders in diseases classified elsewhere	0.199	0.801	0.000
T43.2 Other and unspecified antidepressants	0.198	0.802	0.000
S61 Open wound of wrist and hand	0.197	0.803	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.196	0.804	0.000
# Top node	0.195	0.805	0.000
M40-M43 Deforming dorsopathies	0.195	0.805	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.194	0.806	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.194	0.806	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.191	0.809	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.191	0.809	0.000
E14.7 With multiple complications	0.187	0.812	0.000
E14.6 With other specified complications	0.187	0.812	0.000
E14.5 With peripheral circulatory complications	0.187	0.812	0.000
E14.4 With neurological complications	0.187	0.812	0.000
E14.2 Withrenal complications	0.187	0.812	0.000
E14.1 With ketoacidosis	0.187	0.812	0.000
E14.0 With coma	0.187	0.812	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.187	0.813	0.000
M45-M49 Spondylopathies	0.187	0.813	0.000
M22.8 Other disorders of patella	0.186	0.814	0.000
S61.8 Open wound of other parts of wrist and hand	0.186	0.814	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.186	0.814	0.000
M25.56 Pain in joint (Lower leg)	0.185	0.815	0.000
M70-M79 Other soft tissue disorders	0.185	0.815	0.000
M21.6 Other acquired deformities of ankle and foot	0.185	0.815	0.000
E11.8 With unspecified complications	0.184	0.815	0.000
E13.9 Without complications	0.184	0.815	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.185	0.815	0.000
M25.4 Effusion of joint	0.184	0.816	0.000
M33 Dermatopolymyositis	0.184	0.816	0.000
E16 Other disorders of pancreatic internal secretion	0.183	0.817	0.000
M21.7 Unequal limb length (acquired)	0.183	0.817	0.000
M45 Ankylosing spondylitis	0.183	0.817	0.000
M24 Other specific joint derangements	0.182	0.818	0.000
M22.0 Recurrent dislocation of patella	0.182	0.818	0.000
E11.2 With renal complications	0.181	0.819	0.000
M21.2 Flexion deformity	0.180	0.819	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.179	0.821	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.179	0.821	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.178	0.822	0.000
M86 Osteomyelitis	0.178	0.822	0.000
M60-M63 Disorders of muscles	0.178	0.822	0.000
M94 Other disorders of cartilage	0.178	0.822	0.000
M32 Systemic lupus erythematosus	0.177	0.823	0.000
M25.54 Pain in joint (Hand)	0.177	0.823	0.000
M25.3 Other instability of joint	0.176	0.824	0.000
M35.3 Polymyalgia rheumatica	0.176	0.824	0.000
M41 Scoliosis	0.175	0.825	0.000
E16.2 Hypoglycaemia, unspecified	0.175	0.825	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.174	0.825	0.000
M25.59 Pain in joint (Site unspecified)	0.174	0.826	0.000
M75.4 Impingement syndrome of shoulder	0.174	0.826	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.174	0.826	0.000
H30-H36 Disorders of choroid and retina	0.174	0.826	0.000
M05-M14 Inflammatory polyarthropathies	0.173	0.827	0.000
Q60-Q64 Congenital malformations of the urinary system	0.173	0.827	0.000
M00-M03 Infectious arthropathies	0.172	0.828	0.000
M75 Shoulder lesions	0.172	0.828	0.000
M21.3 Wrist or foot drop (acquired)	0.171	0.829	0.000
E14.3 With ophthalmic complications	0.171	0.829	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.171	0.829	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.170	0.830	0.000
M30 Polyarteritis nodosa and related conditions	0.170	0.830	0.000
E40-E46 Malnutrition	0.169	0.831	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.169	0.831	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.169	0.831	0.000
Chapter VII Diseases of the eye and adnexa	0.169	0.831	0.000
M21.9 Acquired deformity of limb, unspecified	0.168	0.831	0.000
M21.8 Other specified acquired deformities of limbs	0.168	0.831	0.000
M25.9 Joint disorder, unspecified	0.168	0.832	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.167	0.833	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.167	0.833	0.000
T00-T07 Injuries involving multiple body regions	0.166	0.834	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.166	0.834	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.166	0.834	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.166	0.834	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.166	0.834	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.166	0.834	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.166	0.834	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.166	0.834	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.166	0.834	0.000
S40-S49 Injuries to the shoulder and upper arm	0.165	0.834	0.000
S70-S79 Injuries to the hip and thigh	0.165	0.835	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.165	0.835	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.164	0.836	0.000
L20-L30 Dermatitis and eczema	0.164	0.836	0.000
M21.4 Flat foot [pes planus] (acquired)	0.164	0.836	0.000
S65 Injury of blood vessels at wrist and hand level	0.164	0.836	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.164	0.836	0.000
M06 Other rheumatoid arthritis	0.163	0.837	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.162	0.838	0.000
M25.52 Pain in joint (Upper arm)	0.162	0.838	0.000
M22.2 Patellofemoral disorders	0.162	0.838	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.162	0.838	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.162	0.838	0.000
M94.8 Other specified disorders of cartilage	0.161	0.838	0.000
M90 Osteopathies in diseases classified elsewhere	0.161	0.839	0.000
M25.0 Haemarthrosis	0.161	0.839	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.160	0.840	0.000
M22.1 Recurrent subluxation of patella	0.160	0.840	0.000
M22.9 Disorder of patella, unspecified	0.160	0.840	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.160	0.840	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.160	0.840	0.000
Chapter V Mental and behavioural disorders	0.160	0.840	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.159	0.840	0.000
T40.4 Other synthetic narcotics	0.159	0.840	0.000
S61.0 Open wound of finger(s) without damage to nail	0.159	0.841	0.000
Chapter X Diseases of the respiratory system	0.159	0.841	0.000
M25.2 Flail joint	0.159	0.841	0.000
M25.1 Fistula of joint	0.159	0.841	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.159	0.841	0.000
M86.9 Osteomyelitis, unspecified	0.159	0.841	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.159	0.841	0.000
S10-S19 Injuries to the neck	0.158	0.842	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.158	0.842	0.000
S42 Fracture of shoulder and upper arm	0.158	0.842	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.156	0.843	0.000
Q00-Q07 Congenital malformations of the nervous system	0.156	0.844	0.000
M06.9 Rheumatoid arthritis, unspecified	0.155	0.845	0.000
M21.0 Valgus deformity, not elsewhere classified	0.154	0.845	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.154	0.846	0.000
L30 Other dermatitis	0.154	0.846	0.000
S69 Other and unspecified injuries of wrist and hand	0.154	0.846	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.154	0.846	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.154	0.846	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.154	0.846	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.154	0.846	0.000
T36 Poisoning by systemic antibiotics	0.154	0.846	0.000
M35.0 Sicca syndrome [Sjogren]	0.154	0.846	0.000
M75.2 Bicipital tendinitis	0.154	0.846	0.000
J09-J18 Influenza and pneumonia	0.153	0.847	0.000
Q80-Q89 Other congenital malformations	0.153	0.847	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.153	0.847	0.000
E50-E64 Other nutritional deficiencies	0.152	0.848	0.000
Q50-Q56 Congenital malformations of genital organs	0.152	0.848	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.152	0.848	0.000
M41.8 Other forms of scoliosis	0.152	0.848	0.000
Q61 Cystic kidney disease	0.152	0.848	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.152	0.848	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.152	0.848	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.152	0.848	0.000
S68.4 Traumatic amputation of hand at wrist level	0.152	0.848	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.152	0.848	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.151	0.849	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.151	0.849	0.000
M92 Other juvenile osteochondrosis	0.150	0.850	0.000
S42.3 Fracture of shaft of humerus	0.150	0.850	0.000
M93 Other osteochondropathies	0.150	0.850	0.000
M25.37 Other instability of joint (Ankle and foot)	0.150	0.850	0.000
T43.9 Psychotropic drug, unspecified	0.150	0.850	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.150	0.850	0.000
T43.6 Psychostimulants with abuse potential	0.150	0.850	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.150	0.850	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.150	0.850	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.149	0.851	0.000
M65-M68 Disorders of synovium and tendon	0.149	0.851	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.149	0.851	0.000
M34 Systemic sclerosis	0.149	0.851	0.000
M25.7 Osteophyte	0.149	0.851	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.148	0.852	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.148	0.852	0.000
S32 Fracture of lumbar spine and pelvis	0.148	0.852	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.148	0.852	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.148	0.852	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.148	0.852	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.148	0.852	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.148	0.852	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.148	0.852	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.148	0.852	0.000
T44.0 Anticholinesterase agents	0.148	0.852	0.000
F40 Phobic anxiety disorders	0.148	0.852	0.000
M25.40 Effusion of joint (Multiple sites)	0.148	0.852	0.000
T33-T35 Frostbite	0.147	0.853	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.147	0.853	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.147	0.853	0.000
F42 Obsessive-compulsive disorder	0.147	0.853	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.147	0.853	0.000
M40 Kyphosis and lordosis	0.147	0.853	0.000
M71 Other bursopathies	0.147	0.853	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.147	0.853	0.000
H20 Iridocyclitis	0.147	0.853	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.146	0.854	0.000
S67 Crushing injury of wrist and hand	0.146	0.854	0.000
M88 Paget's disease of bone [osteitis deformans]	0.146	0.854	0.000
M25.58 Pain in joint (Other)	0.146	0.854	0.000
M33.1 Other dermatomyositis	0.146	0.854	0.000
M21.24 Flexion deformity (Hand)	0.146	0.854	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.145	0.855	0.000
S42.30 Fracture of shaft of humerus (closed)	0.145	0.855	0.000
M41.9 Scoliosis, unspecified	0.145	0.855	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.145	0.855	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.145	0.855	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.145	0.855	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.144	0.856	0.000
M35.8 Other specified systemic involvement of connective tissue	0.144	0.856	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.144	0.856	0.000
M35.5 Multifocal fibrosclerosis	0.144	0.856	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.144	0.856	0.000
M35.2 Behcet's disease	0.144	0.856	0.000
M35.1 Other overlap syndromes	0.144	0.856	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.144	0.856	0.000
L30.9 Dermatitis, unspecified	0.144	0.856	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.144	0.856	0.000
S79 Other and unspecified injuries of hip and thigh	0.144	0.856	0.000
M25.43 Effusion of joint (Forearm)	0.144	0.856	0.000
M89 Other disorders of bone	0.143	0.857	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.143	0.857	0.000
M62 Other disorders of muscle	0.143	0.857	0.000
Q43 Other congenital malformations of intestine	0.143	0.857	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.142	0.858	0.000
M87 Osteonecrosis	0.142	0.858	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.142	0.858	0.000
M14 Arthropathies in other diseases classified elsewhere	0.141	0.859	0.000
M70.4 Prepatellar bursitis	0.141	0.859	0.000
S90-S99 Injuries to the ankle and foot	0.141	0.859	0.000
L05 Pilonidal cyst	0.141	0.859	0.000
E15 Nondiabetic hypoglycaemic coma	0.140	0.859	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.141	0.859	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.140	0.860	0.000
T00 Superficial injuries involving multiple body regions	0.140	0.860	0.000
T40.6 Other and unspecified narcotics	0.140	0.860	0.000
M42 Spinal osteochondrosis	0.140	0.860	0.000
M24.2 Disorder of ligament	0.140	0.860	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.139	0.861	0.000
Q35-Q37 Cleft lip and cleft palate	0.139	0.861	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.139	0.861	0.000
L03 Cellulitis	0.139	0.861	0.000
L29 Pruritus	0.139	0.861	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.139	0.861	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.139	0.861	0.000
S62 Fracture at wrist and hand level	0.138	0.862	0.000
Q63 Other congenital malformations of kidney	0.138	0.862	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.138	0.862	0.000
E46 Unspecified protein-energy malnutrition	0.137	0.862	0.000
M31 Other necrotising vasculopathies	0.137	0.863	0.000
L10-L14 Bullous disorders	0.137	0.863	0.000
L28 Lichen simplex chronicus and prurigo	0.137	0.863	0.000
M48 Other spondylopathies	0.137	0.863	0.000
M24.5 Contracture of joint	0.137	0.863	0.000
J81 Pulmonary oedema	0.136	0.864	0.000
F40.2 Specific (isolated) phobias	0.136	0.864	0.000
S31 Open wound of abdomen, lower back and pelvis	0.135	0.865	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.135	0.865	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.135	0.865	0.000
S20-S29 Injuries to the thorax	0.135	0.865	0.000
S30.1 Contusion of abdominal wall	0.135	0.865	0.000
S36 Injury of intra-abdominal organs	0.135	0.865	0.000
M49 Spondylopathies in diseases classified elsewhere	0.134	0.865	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.134	0.865	0.000
T59 Toxic effect of other gases, fumes and vapours	0.134	0.866	0.000
H20.9 Iridocyclitis, unspecified	0.134	0.866	0.000
E11.4 With neurological complications	0.134	0.866	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.134	0.866	0.000
J95-J99 Other diseases of the respiratory system	0.134	0.866	0.000
M06.4 Inflammatory polyarthropathy	0.134	0.866	0.000
M86.6 Other chronic osteomyelitis	0.134	0.866	0.000
S30.0 Contusion of lower back and pelvis	0.134	0.866	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.133	0.867	0.000
S37 Injury of urinary and pelvic organs	0.133	0.867	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.133	0.867	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.133	0.867	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.133	0.867	0.000
Q61.0 Congenital single renal cyst	0.133	0.867	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.133	0.867	0.000
M00 Pyogenic arthritis	0.133	0.867	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.133	0.867	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.133	0.867	0.000
M76 Enthesopathies of lower limb, excluding foot	0.133	0.867	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.133	0.867	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.132	0.867	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.132	0.867	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.132	0.867	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.132	0.867	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.132	0.867	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.132	0.867	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.132	0.867	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.132	0.867	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.132	0.867	0.000
M35.7 Hypermobility syndrome	0.132	0.867	0.000
M25.49 Effusion of joint (Site unspecified)	0.132	0.868	0.000
M25.48 Effusion of joint (Other)	0.132	0.868	0.000
M25.44 Effusion of joint (Hand)	0.132	0.868	0.000
M25.42 Effusion of joint (Upper arm)	0.132	0.868	0.000
M25.41 Effusion of joint (Shoulder region)	0.132	0.868	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.132	0.868	0.000
M24.0 Loose body in joint	0.132	0.868	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.132	0.868	0.000
M90.7 Fracture of bone in neoplastic disease	0.132	0.868	0.000
Q39 Congenital malformations of oesophagus	0.132	0.868	0.000
M25.46 Effusion of joint (Lower leg)	0.132	0.868	0.000
M33.9 Dermatopolymyositis, unspecified	0.132	0.868	0.000
M33.2 Polymyositis	0.132	0.868	0.000
M33.0 Juvenile dermatomyositis	0.132	0.868	0.000
J18 Pneumonia, organism unspecified	0.132	0.868	0.000
L21 Seborrhoeic dermatitis	0.132	0.868	0.000
F41 Other anxiety disorders	0.132	0.868	0.000
M21.26 Flexion deformity (Lower leg)	0.131	0.868	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.131	0.869	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.131	0.869	0.000
E16.4 Abnormal secretion of gastrin	0.131	0.869	0.000
E16.3 Increased secretion of glucagon	0.131	0.869	0.000
E16.1 Other hypoglycaemia	0.131	0.869	0.000
Q05 Spina bifida	0.131	0.869	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.131	0.869	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.131	0.869	0.000
M21.78 Unequal limb length (acquired)-Other	0.131	0.869	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.131	0.869	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.131	0.869	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.131	0.869	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.131	0.869	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.131	0.869	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.131	0.869	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.131	0.869	0.000
E61 Deficiency of other nutrient elements	0.131	0.869	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.131	0.869	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.131	0.869	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.131	0.869	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.131	0.869	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.131	0.869	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.131	0.869	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.131	0.869	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.131	0.869	0.000
M24.9 Joint derangement, unspecified	0.131	0.869	0.000
M24.7 Protrusio acetabuli	0.131	0.869	0.000
M24.6 Ankylosis of joint	0.131	0.869	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.131	0.869	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.130	0.869	0.000
L05.9 Pilonidal cyst without abscess	0.130	0.870	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.130	0.870	0.000
M21.29 Flexion deformity (Site unspecified)	0.130	0.870	0.000
M21.28 Flexion deformity (Other)	0.130	0.870	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.130	0.870	0.000
M21.23 Flexion deformity (Forearm)	0.130	0.870	0.000
M21.22 Flexion deformity (Upper arm)	0.130	0.870	0.000
M21.21 Flexion deformity (Shoulder region)	0.130	0.870	0.000
M21.20 Flexion deformity (Multiple sites)	0.130	0.870	0.000
Q17 Other congenital malformations of ear	0.130	0.870	0.000
S42.2 Fracture of upper end of humerus	0.129	0.870	0.000
M24.1 Other articular cartilage disorders	0.129	0.871	0.000
F43 Reaction to severe stress, and adjustment disorders	0.129	0.871	0.000
S79.9 Unspecified injury of hip and thigh	0.129	0.871	0.000
Q18 Other congenital malformations of face and neck	0.129	0.871	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.129	0.871	0.000
T65 Toxic effect of other and unspecified substances	0.129	0.871	0.000
S69.8 Other specified injuries of wrist and hand	0.129	0.871	0.000
F41.9 Anxiety disorder, unspecified	0.129	0.871	0.000
F17.2 Dependence syndrome	0.129	0.871	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.129	0.871	0.000
T40.8 Lysergide [LSD]	0.129	0.871	0.000
T40.7 Cannabis (derivatives)	0.129	0.871	0.000
T40.5 Cocaine	0.129	0.871	0.000
T40.3 Methadone	0.129	0.871	0.000
T40.1 Heroin	0.129	0.871	0.000
T40.0 Opium	0.129	0.871	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.128	0.872	0.000
S61.7 Multiple open wounds of wrist and hand	0.128	0.872	0.000
M25.94 Joint disorder, unspecified (Hand)	0.128	0.872	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.128	0.872	0.000
H49 Paralytic strabismus	0.128	0.872	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.128	0.872	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.128	0.872	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.128	0.872	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.128	0.872	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.128	0.872	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.128	0.872	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.128	0.872	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.128	0.872	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.128	0.872	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.128	0.872	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.128	0.872	0.000
M86.8 Other osteomyelitis	0.128	0.872	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.128	0.872	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.128	0.872	0.000
M86.3 Chronic multifocal osteomyelitis	0.128	0.872	0.000
M86.2 Subacute osteomyelitis	0.128	0.872	0.000
M86.1 Other acute osteomyelitis	0.128	0.872	0.000
M86.0 Acute haematogenous osteomyelitis	0.128	0.872	0.000
M70.2 Olecranon bursitis	0.128	0.872	0.000
M22.3 Other derangements of patella	0.128	0.872	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.128	0.872	0.000
M61 Calcification and ossification of muscle	0.128	0.872	0.000
M60 Myositis	0.128	0.872	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.128	0.872	0.000
M25.34 Other instability of joint (Hand)	0.128	0.872	0.000
M94.3 Chondrolysis	0.127	0.872	0.000
M94.2 Chondromalacia	0.127	0.872	0.000
M94.1 Relapsing polychondritis	0.127	0.872	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.127	0.872	0.000
Chapter XXII Codes for special purposes	0.128	0.872	0.000
M75.9 Shoulder lesion, unspecified	0.127	0.873	0.000
Q43.0 Meckel's diverticulum	0.127	0.873	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.127	0.873	0.000
M32.8 Other forms of systemic lupus erythematosus	0.127	0.873	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.127	0.873	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.127	0.873	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.127	0.873	0.000
M94.9 Disorder of cartilage, unspecified	0.127	0.873	0.000
M25.39 Other instability of joint (Site unspecified)	0.126	0.873	0.000
M25.38 Other instability of joint (Other)	0.126	0.873	0.000
M25.36 Other instability of joint (Lower leg)	0.126	0.873	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.126	0.873	0.000
M25.33 Other instability of joint (Forearm)	0.126	0.873	0.000
M25.32 Other instability of joint (Upper arm)	0.126	0.873	0.000
M25.30 Other instability of joint (Multiple sites)	0.126	0.873	0.000
T51 Toxic effect of alcohol	0.127	0.873	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.126	0.874	0.000
M41.5 Other secondary scoliosis	0.126	0.874	0.000
M41.4 Neuromuscular scoliosis	0.126	0.874	0.000
M41.3 Thoracogenic scoliosis	0.126	0.874	0.000
M41.2 Other idiopathic scoliosis	0.126	0.874	0.000
M41.1 Juvenile idiopathic scoliosis	0.126	0.874	0.000
M41.0 Infantile idiopathic scoliosis	0.126	0.874	0.000
M80-M85 Disorders of bone density and structure	0.125	0.874	0.000
S70 Superficial injury of hip and thigh	0.125	0.875	0.000
Q61.4 Renal dysplasia	0.125	0.875	0.000
H31 Other disorders of choroid	0.125	0.875	0.000
M11 Other crystal arthropathies	0.125	0.875	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.125	0.875	0.000
H30 Chorioretinal inflammation	0.125	0.875	0.000
F44 Dissociative [conversion] disorders	0.125	0.875	0.000
L25 Unspecified contact dermatitis	0.125	0.875	0.000
Q12 Congenital lens malformations	0.125	0.875	0.000
T42.1 Iminostilbenes	0.125	0.875	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.124	0.875	0.000
J14 Pneumonia due to Haemophilus influenzae	0.124	0.876	0.000
J17 Pneumonia in diseases classified elsewhere	0.124	0.876	0.000
M66 Spontaneous rupture of synovium and tendon	0.124	0.876	0.000
M12 Other specific arthropathies	0.124	0.876	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.124	0.876	0.000
M08 Juvenile arthritis	0.124	0.876	0.000
Q64 Other congenital malformations of urinary system	0.124	0.876	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.124	0.876	0.000
M23 Internal derangement of knee	0.124	0.876	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations