TreeWAS – Variant ID: rs9599394

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13 Obstructive and reflux uropathy	0.156	0.844	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.155	0.845	0.000
N13.4 Hydroureter	0.150	0.850	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.147	0.853	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.143	0.857	0.000
N13.3 Other and unspecified hydronephrosis	0.142	0.858	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.121	0.879	0.000
N13.6 Pyonephrosis	0.100	0.900	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.091	0.909	0.000
N13.8 Other obstructive and reflux uropathy	0.080	0.920	0.000
N10-N16 Renal tubulo-interstitial diseases	0.074	0.926	0.000
N10 Acute tubulo-interstitial nephritis	0.072	0.928	0.000
I50.0 Congestive heart failure	0.000	0.931	0.069
I50 Heart failure	0.000	0.943	0.057
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.056	0.944	0.000
I50.1 Left ventricular failure	0.000	0.946	0.054
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.053	0.947	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.048	0.952	0.000
N15 Other renal tubulo-interstitial diseases	0.046	0.954	0.000
N11 Chronic tubulo-interstitial nephritis	0.046	0.954	0.000
I50.9 Heart failure, unspecified	0.000	0.955	0.045
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.038	0.962	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.038	0.962	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.038	0.962	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.038	0.962	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.038	0.962	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.038	0.962	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.038	0.962	0.000
D69 Purpura and other haemorrhagic conditions	0.038	0.962	0.000
D69.6 Thrombocytopenia, unspecified	0.037	0.963	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.035	0.965	0.000
N14.3 Nephropathy induced by heavy metals	0.035	0.965	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.035	0.965	0.000
N14.0 Analgesic nephropathy	0.035	0.965	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.034	0.966	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.033	0.967	0.000
N15.1 Renal and perinephric abscess	0.033	0.967	0.000
N15.0 Balkan nephropathy	0.033	0.967	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.033	0.967	0.000
D69.4 Other primary thrombocytopenia	0.033	0.967	0.000
N11.1 Chronic obstructive pyelonephritis	0.032	0.967	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.032	0.968	0.000
D69.1 Qualitative platelet defects	0.031	0.969	0.000
D68 Other coagulation defects	0.031	0.969	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.030	0.970	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.030	0.970	0.000
D69.5 Secondary thrombocytopenia	0.030	0.970	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.029	0.971	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.029	0.971	0.000
K51.9 Ulcerative colitis, unspecified	0.028	0.972	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.027	0.973	0.000
D69.8 Other specified haemorrhagic conditions	0.027	0.973	0.000
D69.2 Other nonthrombocytopenic purpura	0.027	0.973	0.000
D69.0 Allergic purpura	0.027	0.973	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.027	0.973	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.026	0.973	0.000
D80-D89 Certain disorders involving the immune mechanism	0.027	0.973	0.000
D68.6 Other Thrombophilia	0.026	0.974	0.000
D86 Sarcoidosis	0.026	0.974	0.000
D69.9 Haemorrhagic condition, unspecified	0.026	0.974	0.000
D68.0 Von Willebrand's disease	0.026	0.974	0.000
D68.4 Acquired coagulation factor deficiency	0.025	0.975	0.000
D66 Hereditary factor VIII deficiency	0.025	0.975	0.000
K50.0 Crohn's disease of small intestine	0.025	0.975	0.000
D67 Hereditary factor IX deficiency	0.025	0.975	0.000
D55-D59 Haemolytic anaemias	0.024	0.976	0.000
K91.3 Postoperative intestinal obstruction	0.024	0.976	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.024	0.976	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.024	0.976	0.000
K51 Ulcerative colitis	0.023	0.977	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.023	0.977	0.000
D68.9 Coagulation defect, unspecified	0.023	0.977	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.023	0.977	0.000
D86.9 Sarcoidosis, unspecified	0.023	0.977	0.000
D68.5 Primary Thrombophilia	0.023	0.977	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.022	0.978	0.000
D86.3 Sarcoidosis of skin	0.022	0.978	0.000
D86.0 Sarcoidosis of lung	0.022	0.978	0.000
D80 Immunodeficiency with predominantly antibody defects	0.021	0.978	0.000
D68.2 Hereditary deficiency of other clotting factors	0.021	0.979	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.021	0.979	0.000
D59 Acquired haemolytic anaemia	0.021	0.979	0.000
D58 Other hereditary haemolytic anaemias	0.021	0.979	0.000
D76.3 Other histiocytosis syndromes	0.021	0.979	0.000
D68.1 Hereditary factor XI deficiency	0.020	0.979	0.000
K50 Crohn's disease [regional enteritis]	0.020	0.980	0.000
R73.9 Hyperglycaemia, unspecified	0.020	0.980	0.000
K51.4 Pseudopolyposis of colon	0.020	0.980	0.000
D86.8 Sarcoidosis of other and combined sites	0.020	0.980	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.020	0.980	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.020	0.980	0.000
D75 Other diseases of blood and blood-forming organs	0.020	0.980	0.000
D82 Immunodeficiency associated with other major defects	0.019	0.981	0.000
D81 Combined immunodeficiencies	0.019	0.981	0.000
D84 Other immunodeficiencies	0.019	0.981	0.000
D83 Common variable immunodeficiency	0.019	0.981	0.000
K50-K52 Noninfective enteritis and colitis	0.019	0.981	0.000
D86.1 Sarcoidosis of lymph nodes	0.018	0.981	0.000
D56 Thalassaemia	0.018	0.981	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.018	0.982	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.018	0.982	0.000
K91.4 Colostomy and enterostomy malfunction	0.018	0.982	0.000
D57 Sickle-cell disorders	0.018	0.982	0.000
D55 Anaemia due to enzyme disorders	0.018	0.982	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.018	0.982	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.017	0.982	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.017	0.983	0.000
K50.9 Crohn's disease, unspecified	0.017	0.983	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.017	0.983	0.000
D59.1 Other autoimmune haemolytic anaemias	0.017	0.983	0.000
D73 Diseases of spleen	0.017	0.983	0.000
K91.5 Postcholecystectomy syndrome	0.017	0.983	0.000
D75.1 Secondary polycythaemia	0.016	0.983	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.016	0.984	0.000
K51.8 Other ulcerative colitis	0.016	0.984	0.000
D74 Methaemoglobinaemia	0.016	0.984	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.016	0.984	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.016	0.984	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.016	0.984	0.000
K91.1 Postgastric surgery syndromes	0.016	0.984	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.016	0.984	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.016	0.984	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.016	0.984	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.016	0.984	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.016	0.984	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.016	0.984	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.016	0.984	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.016	0.984	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.016	0.984	0.000
D58.0 Hereditary spherocytosis	0.015	0.984	0.000
D75.0 Familial erythrocytosis	0.015	0.985	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.015	0.985	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.015	0.985	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.015	0.985	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.015	0.985	0.000
D58.2 Other haemoglobinopathies	0.015	0.985	0.000
D58.1 Hereditary elliptocytosis	0.015	0.985	0.000
D59.8 Other acquired haemolytic anaemias	0.015	0.985	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.015	0.985	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.015	0.985	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.015	0.985	0.000
D59.3 Haemolytic-uraemic syndrome	0.015	0.985	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.015	0.985	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.015	0.985	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.015	0.985	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.015	0.985	0.000
D89.1 Cryoglobulinaemia	0.015	0.985	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.014	0.985	0.000
D89.3 Immune reconstitution syndrome	0.014	0.985	0.000
D56.3 Thalassaemia trait	0.014	0.986	0.000
D84.1 Defects in the complement system	0.014	0.986	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.014	0.986	0.000
D73.8 Other diseases of spleen	0.014	0.986	0.000
D81.9 Combined immunodeficiency, unspecified	0.014	0.986	0.000
D81.8 Other combined immunodeficiencies	0.014	0.986	0.000
D81.7 Major histocompatibility complex class II deficiency	0.014	0.986	0.000
D81.6 Major histocompatibility complex class I deficiency	0.014	0.986	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.014	0.986	0.000
D81.4 Nezelof's syndrome	0.014	0.986	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.014	0.986	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.014	0.986	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.014	0.986	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.014	0.986	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.014	0.986	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.014	0.986	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.014	0.986	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.014	0.986	0.000
D82.2 Immunodeficiency with short-limbed stature	0.014	0.986	0.000
D82.1 Di George's syndrome	0.014	0.986	0.000
D82.0 Wiskott-Aldrich syndrome	0.014	0.986	0.000
D84.8 Other specified immunodeficiencies	0.014	0.986	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.014	0.986	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.014	0.986	0.000
D83.8 Other common variable immunodeficiencies	0.014	0.986	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.014	0.986	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.014	0.986	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.014	0.986	0.000
D83.9 Common variable immunodeficiency, unspecified	0.014	0.986	0.000
D84.9 Immunodeficiency, unspecified	0.014	0.986	0.000
D72 Other disorders of white blood cells	0.014	0.986	0.000
D56.9 Thalassaemia, unspecified	0.013	0.986	0.000
D56.8 Other thalassaemias	0.013	0.986	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.013	0.986	0.000
D56.2 Delta-beta thalassaemia	0.013	0.986	0.000
D56.0 Alpha thalassaemia	0.013	0.986	0.000
D56.1 Beta thalassaemia	0.013	0.987	0.000
D75.2 Essential thrombocytosis	0.013	0.987	0.000
D73.5 Infarction of spleen	0.013	0.987	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.013	0.987	0.000
D55.8 Other anaemias due to enzyme disorders	0.013	0.987	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.013	0.987	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.013	0.987	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.013	0.987	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.013	0.987	0.000
D57.8 Other sickle-cell disorders	0.013	0.987	0.000
D57.3 Sickle-cell trait	0.013	0.987	0.000
D57.2 Double heterozygous sickling disorders	0.013	0.987	0.000
D57.1 Sickle-cell anaemia without crisis	0.013	0.987	0.000
D57.0 Sickle-cell anaemia with crisis	0.013	0.987	0.000
K50.1 Crohn's disease of large intestine	0.012	0.988	0.000
D73.9 Disease of spleen, unspecified	0.012	0.988	0.000
D73.3 Abscess of spleen	0.012	0.988	0.000
D73.2 Chronic congestive splenomegaly	0.012	0.988	0.000
D73.1 Hypersplenism	0.012	0.988	0.000
D74.9 Methaemoglobinaemia, unspecified	0.012	0.988	0.000
D74.8 Other methaemoglobinaemias	0.012	0.988	0.000
D74.0 Congenital methaemoglobinaemia	0.012	0.988	0.000
D73.4 Cyst of spleen	0.012	0.988	0.000
D50-D53 Nutritional anaemias	0.011	0.989	0.000
D73.0 Hyposplenism	0.010	0.990	0.000
D72.9 Disorder of white blood cells, unspecified	0.010	0.990	0.000
D72.0 Genetic anomalies of leukocytes	0.010	0.990	0.000
K51.5 Mucosal proctocolitis	0.010	0.990	0.000
D68.8 Other specified coagulation defects	0.009	0.990	0.000
D72.1 Eosinophilia	0.009	0.990	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.009	0.991	0.000
Z74.0 Reduced mobility	0.000	0.991	0.009
D75.9 Disease of blood and blood-forming organs, unspecified	0.009	0.991	0.000
D72.8 Other specified disorders of white blood cells	0.008	0.992	0.000
K52 Other non-infective gastro-enteritis and colitis	0.008	0.992	0.000
K51.2 Ulcerative (chronic) proctitis	0.008	0.992	0.000
D53 Other nutritional anaemias	0.008	0.992	0.000
K90-K93 Other diseases of the digestive system	0.008	0.992	0.000
D50 Iron deficiency anaemia	0.008	0.992	0.000
D52 Folate deficiency anaemia	0.007	0.993	0.000
K52.1 Toxic gastro-enteritis and colitis	0.007	0.993	0.000
K50.8 Other Crohn's disease	0.006	0.993	0.001
K52.3 Indeterminate colitis	0.007	0.993	0.000
K75.9 Inflammatory liver disease, unspecified	0.007	0.993	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.994	0.006
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
Q76.0 Spina bifida occulta	0.006	0.994	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.006	0.994	0.000
H53.8 Other visual disturbances	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
I67.2 Cerebral atherosclerosis	0.000	0.994	0.006
O63.1 Prolonged second stage (of labour)	0.000	0.994	0.006
D53.8 Other specified nutritional anaemias	0.006	0.994	0.000
D53.2 Scorbutic anaemia	0.006	0.994	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.006	0.994	0.000
D53.0 Protein deficiency anaemia	0.006	0.994	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.006	0.994	0.000
D50.1 Sideropenic dysphagia	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
N30.1 Interstitial cystitis (chronic)	0.006	0.994	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.005	0.994	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
D53.9 Nutritional anaemia, unspecified	0.005	0.995	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.005	0.995	0.000
D52.8 Other folate deficiency anaemias	0.005	0.995	0.000
D52.1 Drug-induced folate deficiency anaemia	0.005	0.995	0.000
D52.0 Dietary folate deficiency anaemia	0.005	0.995	0.000
K65.0 Acute peritonitis	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
I67 Other cerebrovascular diseases	0.000	0.995	0.005
Q66 Congenital deformities of feet	0.005	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.005	0.995	0.000
Q43 Other congenital malformations of intestine	0.005	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.005	0.995	0.000
Q45 Other congenital malformations of digestive system	0.005	0.995	0.000
Q63 Other congenital malformations of kidney	0.005	0.995	0.000
D60-D64 Aplastic and other anaemias	0.005	0.995	0.000
D51 Vitamin B12 deficiency anaemia	0.005	0.995	0.000
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.005	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.005	0.995	0.000
Q76.7 Congenital malformation of sternum	0.005	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.005	0.995	0.000
Q76.5 Cervical rib	0.005	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.005	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.005	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.005	0.995	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.005	0.995	0.000
K40-K46 Hernia	0.005	0.995	0.000
Q66.8 Other congenital deformities of feet	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
Z74 Problems related to care-provider dependency	0.000	0.995	0.005
I67.8 Other specified cerebrovascular diseases	0.000	0.995	0.005
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
K65-K67 Diseases of peritoneum	0.005	0.995	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.005	0.995	0.000
K46 Unspecified abdominal hernia	0.005	0.995	0.000
K43 Ventral hernia	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
R73 Elevated blood glucose level	0.004	0.995	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.995	0.005
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.995	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.995	0.000
Chapter XI Diseases of the digestive system	0.005	0.995	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.995	0.000
K66 Other disorders of peritoneum	0.004	0.995	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.996	0.004
K90 Intestinal malabsorption	0.004	0.996	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.004	0.996	0.000
K93.1 Megacolon in Chagas' disease	0.004	0.996	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
Q45.8 Other specified congenital malformations of digestive system	0.004	0.996	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.004	0.996	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q43.3 Congenital malformations of intestinal fixation	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
K66.8 Other specified disorders of peritoneum	0.004	0.996	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.004	0.996	0.000
K66.0 Peritoneal adhesions	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
Q63.0 Accessory kidney	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
H53.9 Visual disturbance, unspecified	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
N30.0 Acute cystitis	0.004	0.996	0.000
Q65.8 Other congenital deformities of hip	0.004	0.996	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.996	0.004
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q51.3 Bicornate uterus	0.004	0.996	0.000
K40 Inguinal hernia	0.004	0.996	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
H53 Visual disturbances	0.004	0.996	0.000
K44 Diaphragmatic hernia	0.004	0.996	0.000
K65 Peritonitis	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.996	0.004
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.996	0.004
I67.5 Moyamoya disease	0.000	0.996	0.004
I67.4 Hypertensive encephalopathy	0.000	0.996	0.004
I67.3 Progressive vascular leukoencephalopathy	0.000	0.996	0.004
Q21.3 Tetralogy of Fallot	0.004	0.996	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.004	0.996	0.000
D52.9 Folate deficiency anaemia, unspecified	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
Q66.9 Congenital deformity of feet, unspecified	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
J33.8 Other polyp of sinus	0.000	0.996	0.004
Q63.2 Ectopic kidney	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.004	0.996	0.000
Q43.7 Persistent cloaca	0.004	0.996	0.000
Q43.6 Congenital fistula of rectum and anus	0.004	0.996	0.000
Q43.5 Ectopic anus	0.004	0.996	0.000
Q43.4 Duplication of intestine	0.004	0.996	0.000
Q43.2 Other congenital functional disorders of colon	0.004	0.996	0.000
Q43.1 Hirschsprung's disease	0.004	0.996	0.000
K75 Other inflammatory liver diseases	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.004	0.996	0.000
Q65.6 Unstable hip	0.004	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.004	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.004	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.004	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
Q52.5 Fusion of labia	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.996	0.000
Q45.2 Congenital pancreatic cyst	0.004	0.996	0.000
Q45.1 Annular pancreas	0.004	0.996	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.004	0.996	0.000
Q63.8 Other specified congenital malformations of kidney	0.004	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.004	0.996	0.000
N30 Cystitis	0.004	0.996	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.004	0.996	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.004	0.996	0.000
D51.2 Transcobalamin II deficiency	0.004	0.996	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.996	0.004
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
K90.8 Other intestinal malabsorption	0.004	0.996	0.000
M19.0 Primary arthrosis of other joints	0.000	0.996	0.004
K70 Alcoholic liver disease	0.004	0.996	0.000
Q96 Turner's syndrome	0.003	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.996	0.000
Q68.3 Congenital bowing of femur	0.003	0.996	0.000
Q68.2 Congenital deformity of knee	0.003	0.996	0.000
Q68.1 Congenital deformity of hand	0.003	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.996	0.000
Q69.9 Polydactyly, unspecified	0.003	0.996	0.000
Q69.2 Accessory toe(s)	0.003	0.996	0.000
Q69.1 Accessory thumb(s)	0.003	0.996	0.000
Q69.0 Accessory finger(s)	0.003	0.996	0.000
Q70.9 Syndactyly, unspecified	0.003	0.996	0.000
Q70.4 Polysyndactyly	0.003	0.996	0.000
Q70.3 Webbed toes	0.003	0.996	0.000
Q70.2 Fused toes	0.003	0.996	0.000
Q70.1 Webbed fingers	0.003	0.996	0.000
Q70.0 Fused fingers	0.003	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.996	0.000
Q71.6 Lobster-claw hand	0.003	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.996	0.000
Q72.7 Split foot	0.003	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.996	0.000
Q75.3 Macrocephaly	0.003	0.996	0.000
Q75.2 Hypertelorism	0.003	0.996	0.000
Q75.1 Craniofacial dysostosis	0.003	0.996	0.000
Q75.0 Craniosynostosis	0.003	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.996	0.000
Q77.5 Diastrophic dysplasia	0.003	0.996	0.000
Q77.4 Achondroplasia	0.003	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.996	0.000
Q77.2 Short rib syndrome	0.003	0.996	0.000
Q77.1 Thanatophoric short stature	0.003	0.996	0.000
Q77.0 Achondrogenesis	0.003	0.996	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.996	0.003
Z74.3 Need for continuous supervision	0.000	0.996	0.003
Q15 Other congenital malformations of eye	0.003	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.996	0.000
Q40.1 Congenital hiatus hernia	0.003	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.996	0.000
K70-K77 Diseases of liver	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.996	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.003	0.996	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.003	0.996	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.003	0.996	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations