TreeWAS – Variant ID: rs9913352

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E65-E68 Obesity and other hyperalimentation	0.999	0.001	0.000
E66 Obesity	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
E70-E90 Metabolic disorders	0.997	0.003	0.000
E66.9 Obesity, unspecified	0.996	0.004	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.995	0.005	0.000
Chapter VII Diseases of the eye and adnexa	0.991	0.009	0.000
Chapter V Mental and behavioural disorders	0.986	0.014	0.000
F30-F39 Mood [affective] disorders	0.984	0.016	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.981	0.019	0.000
F32 Depressive episode	0.978	0.022	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.962	0.038	0.000
E66.8 Other obesity	0.962	0.038	0.000
F32.9 Depressive episode, unspecified	0.959	0.041	0.000
S80-S89 Injuries to the knee and lower leg	0.957	0.043	0.000
Chapter VIII Diseases of the ear and mastoid process	0.957	0.043	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.956	0.044	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.955	0.045	0.000
E10-E14 Diabetes mellitus	0.953	0.047	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.948	0.052	0.000
E00-E07 Disorders of thyroid gland	0.945	0.055	0.000
S90-S99 Injuries to the ankle and foot	0.941	0.059	0.000
O00-O08 Pregnancy with abortive outcome	0.941	0.059	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.939	0.061	0.000
E11 Non-insulin-dependent diabetes mellitus	0.939	0.061	0.000
H04 Disorders of lachrymal system	0.937	0.063	0.000
H65-H75 Diseases of middle ear and mastoid	0.936	0.064	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.935	0.065	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.934	0.066	0.000
S00-S09 Injuries to the head	0.926	0.074	0.000
E05.9 Thyrotoxicosis, unspecified	0.926	0.074	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.926	0.074	0.000
E83 Disorders of mineral metabolism	0.925	0.075	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.920	0.080	0.000
O02 Other abnormal products of conception	0.919	0.081	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.915	0.085	0.000
S32 Fracture of lumbar spine and pelvis	0.914	0.085	0.000
E11.9 Without complications	0.914	0.086	0.000
E83.5 Disorders of calcium metabolism	0.912	0.088	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.910	0.090	0.000
S89 Other and unspecified injuries of lower leg	0.903	0.097	0.000
S50-S59 Injuries to the elbow and forearm	0.902	0.098	0.000
O02.1 Missed abortion	0.901	0.099	0.000
S06 Intracranial injury	0.891	0.109	0.000
Chapter VI Diseases of the nervous system	0.889	0.111	0.000
D50-D53 Nutritional anaemias	0.887	0.113	0.000
E87.7 Fluid overload	0.883	0.117	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.879	0.121	0.000
Chapter IX Diseases of the circulatory system	0.877	0.123	0.000
E87.2 Acidosis	0.876	0.124	0.000
S32.0 Fracture of lumbar vertebra	0.875	0.125	0.000
D50 Iron deficiency anaemia	0.874	0.126	0.000
E87.6 Hypokalaemia	0.867	0.133	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.865	0.135	0.000
S89.9 Unspecified injury of lower leg	0.864	0.136	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.863	0.137	0.000
O80-O84 Delivery	0.862	0.138	0.000
S92 Fracture of foot, except ankle	0.862	0.138	0.000
E87.5 Hyperkalaemia	0.860	0.140	0.000
H71 Cholesteatoma of middle ear	0.856	0.144	0.000
Chapter XIV Diseases of the genitourinary system	0.854	0.146	0.000
H66 Suppurative and unspecified otitis media	0.850	0.150	0.000
S06.0 Concussion	0.850	0.150	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.849	0.151	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.848	0.152	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.842	0.158	0.000
D50.9 Iron deficiency anaemia, unspecified	0.838	0.162	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.837	0.163	0.000
H43-H45 Disorders of vitreous body and globe	0.836	0.164	0.000
H55-H59 Other disorders of eye and adnexa	0.834	0.166	0.000
N25-N29 Other disorders of kidney and ureter	0.828	0.172	0.000
G35 Multiple sclerosis	0.826	0.174	0.000
I10-I15 Hypertensive diseases	0.825	0.175	0.000
H04.2 Epiphora	0.824	0.176	0.000
S06.00 Concussion (without open intracranial wound)	0.820	0.180	0.000
S52 Fracture of forearm	0.817	0.183	0.000
D50.8 Other iron deficiency anaemias	0.816	0.184	0.000
S92.0 Fracture of calcaneus	0.812	0.188	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.810	0.190	0.000
S00 Superficial injury of head	0.810	0.190	0.000
E11.4 With neurological complications	0.809	0.191	0.000
N30-N39 Other diseases of urinary system	0.809	0.191	0.000
O82 Single delivery by Caesarean section	0.805	0.195	0.000
E89.0 Postprocedural hypothyroidism	0.804	0.196	0.000
H18 Other disorders of cornea	0.794	0.206	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.789	0.211	0.000
H66.9 Otitis media, unspecified	0.789	0.211	0.000
S52.5 Fracture of lower end of radius	0.789	0.211	0.000
F31 Bipolar affective disorder	0.787	0.213	0.000
I30-I52 Other forms of heart disease	0.786	0.214	0.000
F80-F89 Disorders of psychological development	0.784	0.215	0.000
H74 Other disorders of middle ear and mastoid	0.784	0.216	0.000
N17-N19 Renal failure	0.782	0.218	0.000
I74 Arterial embolism and thrombosis	0.782	0.218	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.782	0.218	0.000
H50 Other strabismus	0.781	0.219	0.000
I51 Complications and ill-defined descriptions of heart disease	0.781	0.219	0.000
Chapter XXII Codes for special purposes	0.779	0.220	0.000
H69 Other disorders of Eustachian tube	0.778	0.222	0.000
D60-D64 Aplastic and other anaemias	0.778	0.222	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.777	0.223	0.000
S92.00 Fracture of calcaneus (closed)	0.776	0.224	0.000
N30 Cystitis	0.776	0.224	0.000
H30-H36 Disorders of choroid and retina	0.775	0.225	0.000
G70-G73 Diseases of myoneural junction and muscle	0.774	0.226	0.000
F34 Persistent mood [affective] disorders	0.773	0.227	0.000
I73 Other peripheral vascular diseases	0.772	0.228	0.000
S52.50 Fracture of lower end of radius (closed)	0.769	0.231	0.000
H05 Disorders of orbit	0.768	0.232	0.000
E65 Localised adiposity	0.767	0.233	0.000
H20 Iridocyclitis	0.767	0.233	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.760	0.240	0.000
S70-S79 Injuries to the hip and thigh	0.759	0.241	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.759	0.241	0.000
S90 Superficial injury of ankle and foot	0.757	0.243	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.754	0.246	0.000
S99 Other and unspecified injuries of ankle and foot	0.753	0.247	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.753	0.247	0.000
H01 Other inflammation of eyelid	0.751	0.249	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.750	0.250	0.000
S06.2 Diffuse brain injury	0.748	0.252	0.000
I51.8 Other ill-defined heart diseases	0.747	0.253	0.000
F20 Schizophrenia	0.746	0.254	0.000
I12 Hypertensive renal disease	0.744	0.256	0.000
S10-S19 Injuries to the neck	0.743	0.257	0.000
S81 Open wound of lower leg	0.742	0.258	0.000
F39 Unspecified mood [affective] disorder	0.742	0.258	0.000
N32 Other disorders of bladder	0.742	0.258	0.000
S86 Injury of muscle and tendon at lower leg level	0.740	0.260	0.000
S80 Superficial injury of lower leg	0.738	0.261	0.000
H60-H62 Diseases of external ear	0.738	0.262	0.000
F33 Recurrent depressive disorder	0.737	0.263	0.000
N00-N08 Glomerular diseases	0.736	0.263	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.735	0.265	0.000
S31 Open wound of abdomen, lower back and pelvis	0.734	0.266	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.732	0.267	0.000
E11.5 With peripheral circulatory complications	0.731	0.269	0.000
F30 Manic episode	0.730	0.270	0.000
E06 Thyroiditis	0.728	0.272	0.000
S32.4 Fracture of acetabulum	0.728	0.272	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.727	0.273	0.000
T79-T79 Certain early complications of trauma	0.724	0.276	0.000
H73 Other disorders of tympanic membrane	0.722	0.278	0.000
O82.9 Delivery by Caesarean section, unspecified	0.722	0.278	0.000
S50 Superficial injury of forearm	0.721	0.279	0.000
H80-H83 Diseases of inner ear	0.721	0.279	0.000
N32.9 Bladder disorder, unspecified	0.721	0.279	0.000
E13 Other specified diabetes mellitus	0.720	0.280	0.000
O82.0 Delivery by elective Caesarean section	0.718	0.282	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.282	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.717	0.283	0.000
I49 Other cardiac arrhythmias	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283	0.000
E67 Other hyperalimentation	0.716	0.283	0.000
E68 Sequelae of hyperalimentation	0.716	0.283	0.000
I78 Diseases of capillaries	0.716	0.283	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.716	0.284	0.000
E66.1 Drug-induced obesity	0.716	0.284	0.000
E66.0 Obesity due to excess calories	0.716	0.284	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.284	0.000
E85 Amyloidosis	0.715	0.285	0.000
E84 Cystic fibrosis	0.715	0.285	0.000
E79 Disorders of purine and pyrimidine metabolism	0.715	0.285	0.000
E77 Disorders of glycoprotein metabolism	0.715	0.285	0.000
E76 Disorders of glycosaminoglycan metabolism	0.715	0.285	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.715	0.285	0.000
E74 Other disorders of carbohydrate metabolism	0.715	0.285	0.000
E73 Lactose intolerance	0.715	0.285	0.000
E72 Other disorders of amino-acid metabolism	0.715	0.285	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.715	0.285	0.000
E70 Disorders of aromatic amino-acid metabolism	0.715	0.285	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.715	0.285	0.000
S00.0 Superficial injury of scalp	0.715	0.285	0.000
H21 Other disorders of iris and ciliary body	0.715	0.285	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.714	0.286	0.000
Chapter X Diseases of the respiratory system	0.714	0.286	0.000
N30.8 Other cystitis	0.714	0.286	0.000
D62 Acute posthaemorrhagic anaemia	0.714	0.286	0.000
E87.4 Mixed disorder of acid-base balance	0.714	0.286	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.711	0.289	0.000
S05 Injury of eye and orbit	0.710	0.290	0.000
H43 Disorders of vitreous body	0.708	0.292	0.000
N30.9 Cystitis, unspecified	0.707	0.293	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.707	0.293	0.000
F70-F79 Mental retardation	0.707	0.293	0.000
S00.8 Superficial injury of other parts of head	0.705	0.295	0.000
F38 Other mood [affective] disorders	0.705	0.295	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.705	0.295	0.000
O85-O92 Complications predominantly related to the puerperium	0.704	0.296	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.703	0.297	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.703	0.297	0.000
I12.0 Hypertensive renal disease with renal failure	0.702	0.298	0.000
F32.8 Other depressive episodes	0.701	0.299	0.000
E11.6 With other specified complications	0.698	0.302	0.000
S32.5 Fracture of pubis	0.698	0.302	0.000
H04.9 Disorder of lachrymal system, unspecified	0.698	0.302	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.697	0.302	0.000
H50.1 Divergent concomitant strabismus	0.697	0.303	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.696	0.304	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.695	0.305	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.695	0.305	0.000
I51.9 Heart disease, unspecified	0.693	0.307	0.000
H10-H13 Disorders of conjunctiva	0.693	0.307	0.000
J95-J99 Other diseases of the respiratory system	0.691	0.309	0.000
N18 Chronic renal failure	0.691	0.309	0.000
S02 Fracture of skull and facial bones	0.688	0.312	0.000
O81 Single delivery by forceps and vacuum extractor	0.688	0.312	0.000
N28.0 Ischaemia and infarction of kidney	0.687	0.313	0.000
T17 Foreign body in respiratory tract	0.686	0.314	0.000
S88 Traumatic amputation of lower leg	0.686	0.314	0.000
S87 Crushing injury of lower leg	0.686	0.314	0.000
S85 Injury of blood vessels at lower leg level	0.686	0.314	0.000
S84 Injury of nerves at lower leg level	0.686	0.314	0.000
I70 Atherosclerosis	0.686	0.314	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.686	0.314	0.000
O97 Death from sequelae of direct obstetric causes	0.686	0.314	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.686	0.314	0.000
O95 Obstetric death of unspecified cause	0.686	0.314	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.686	0.314	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.685	0.315	0.000
D53 Other nutritional anaemias	0.685	0.315	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.685	0.315	0.000
S37 Injury of urinary and pelvic organs	0.685	0.315	0.000
S36 Injury of intra-abdominal organs	0.685	0.315	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.685	0.315	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.685	0.315	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.685	0.315	0.000
E12 Malnutrition-related diabetes mellitus	0.683	0.317	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.683	0.317	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.683	0.317	0.000
I71 Aortic aneurysm and dissection	0.682	0.318	0.000
N20-N23 Urolithiasis	0.681	0.319	0.000
I72 Other aneurysm	0.681	0.319	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.680	0.320	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.678	0.322	0.000
E00 Congenital iodine-deficiency syndrome	0.678	0.322	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.678	0.322	0.000
I73.9 Peripheral vascular disease, unspecified	0.677	0.323	0.000
I05-I09 Chronic rheumatic heart diseases	0.676	0.324	0.000
S06.8 Other intracranial injuries	0.676	0.324	0.000
H36 Retinal disorders in diseases classified elsewhere	0.676	0.324	0.000
S98 Traumatic amputation of ankle and foot	0.675	0.325	0.000
S97 Crushing injury of ankle and foot	0.675	0.325	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.675	0.325	0.000
S95 Injury of blood vessels at ankle and foot level	0.675	0.325	0.000
S94 Injury of nerves at ankle and foot level	0.675	0.325	0.000
O03 Spontaneous abortion	0.675	0.325	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.675	0.325	0.000
O07 Failed attempted abortion	0.675	0.325	0.000
O06 Unspecified abortion	0.675	0.325	0.000
O05 Other abortion	0.675	0.325	0.000
O01 Hydatidiform mole	0.675	0.325	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.673	0.327	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.673	0.327	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.673	0.327	0.000
E11.8 With unspecified complications	0.673	0.327	0.000
E11.7 With multiple complications	0.673	0.327	0.000
E11.1 With ketoacidosis	0.673	0.327	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.673	0.327	0.000
S82 Fracture of lower leg, including ankle	0.672	0.328	0.000
H04.8 Other disorders of lachrymal system	0.672	0.328	0.000
H04.6 Other changes in lachrymal passages	0.672	0.328	0.000
H04.4 Chronic inflammation of lachrymal passages	0.672	0.328	0.000
H04.0 Dacryoadenitis	0.672	0.328	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.671	0.329	0.000
H68 Eustachian salpingitis and obstruction	0.671	0.329	0.000
H67 Otitis media in diseases classified elsewhere	0.671	0.329	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.670	0.330	0.000
E05.8 Other thyrotoxicosis	0.670	0.330	0.000
E05.5 Thyroid crisis or storm	0.670	0.330	0.000
E05.4 Thyrotoxicosis factitia	0.670	0.330	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.670	0.330	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.670	0.330	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.670	0.330	0.000
H17 Corneal scars and opacities	0.670	0.330	0.000
E11.0 With coma	0.669	0.331	0.000
F60-F69 Disorders of adult personality and behaviour	0.669	0.331	0.000
E50-E64 Other nutritional deficiencies	0.669	0.331	0.000
E11.2 With renal complications	0.669	0.331	0.000
S06.4 Epidural haemorrhage	0.668	0.332	0.000
N26 Unspecified contracted kidney	0.668	0.332	0.000
H70 Mastoiditis and related conditions	0.668	0.332	0.000
H20.9 Iridocyclitis, unspecified	0.666	0.334	0.000
F22 Persistent delusional disorders	0.665	0.335	0.000
H18.5 Hereditary corneal dystrophies	0.665	0.335	0.000
I11 Hypertensive heart disease	0.665	0.335	0.000
S08 Traumatic amputation of part of head	0.664	0.336	0.000
S07 Crushing injury of head	0.664	0.336	0.000
S04 Injury of cranial nerves	0.664	0.336	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.664	0.336	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.663	0.337	0.000
E83.8 Other disorders of mineral metabolism	0.663	0.337	0.000
E83.2 Disorders of zinc metabolism	0.663	0.337	0.000
E83.0 Disorders of copper metabolism	0.663	0.337	0.000
S00.7 Multiple superficial injuries of head	0.662	0.338	0.000
O02.9 Abnormal product of conception, unspecified	0.659	0.341	0.000
O02.8 Other specified abnormal products of conception	0.659	0.341	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.659	0.341	0.000
I30 Acute pericarditis	0.659	0.341	0.000
G71 Primary disorders of muscles	0.659	0.341	0.000
I49.8 Other specified cardiac arrhythmias	0.659	0.341	0.000
S32.3 Fracture of ilium	0.658	0.342	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.656	0.344	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.656	0.344	0.000
S32.2 Fracture of coccyx	0.656	0.344	0.000
G20-G26 Extrapyramidal and movement disorders	0.654	0.346	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.654	0.346	0.000
H18.4 Corneal degeneration	0.654	0.346	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.653	0.347	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.653	0.347	0.000
H15 Disorders of sclera	0.653	0.347	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.652	0.348	0.000
H43.1 Vitreous haemorrhage	0.652	0.348	0.000
O04 Medical abortion	0.652	0.348	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.651	0.349	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.651	0.349	0.000
S89.8 Other specified injuries of lower leg	0.647	0.353	0.000
S89.7 Multiple injuries of lower leg	0.647	0.353	0.000
S89.1 Other specified injuries of lower leg	0.647	0.353	0.000
S89.0 Multiple injuries of lower leg	0.647	0.353	0.000
F20.0 Paranoid schizophrenia	0.647	0.353	0.000
S59 Other and unspecified injuries of forearm	0.647	0.353	0.000
S58 Traumatic amputation of forearm	0.647	0.353	0.000
S57 Crushing injury of forearm	0.647	0.353	0.000
S56 Injury of muscle and tendon at forearm level	0.647	0.353	0.000
S55 Injury of blood vessels at forearm level	0.647	0.353	0.000
S54 Injury of nerves at forearm level	0.647	0.353	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.647	0.353	0.000
I15 Secondary hypertension	0.646	0.354	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.646	0.354	0.000
F25 Schizoaffective disorders	0.646	0.354	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.645	0.355	0.000
H55 Nystagmus and other irregular eye movements	0.643	0.357	0.000
H52 Disorders of refraction and accommodation	0.641	0.359	0.000
N17 Acute renal failure	0.641	0.359	0.000
E87.3 Alkalosis	0.641	0.359	0.000
N32.1 Vesicointestinal fistula	0.641	0.359	0.000
S20-S29 Injuries to the thorax	0.640	0.359	0.000
S32.1 Fracture of sacrum	0.640	0.359	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.640	0.360	0.000
S06.9 Intracranial injury, unspecified	0.638	0.361	0.000
S06.7 Intracranial injury with prolonged coma	0.638	0.361	0.000
S06.1 Traumatic cerebral oedema	0.638	0.361	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.638	0.362	0.000
H05.2 Exophthalmic conditions	0.638	0.362	0.000
H69.8 Other specified disorders of Eustachian tube	0.637	0.363	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.637	0.363	0.000
I51.4 Myocarditis, unspecified	0.637	0.363	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.637	0.363	0.000
N27 Small kidney of unknown cause	0.636	0.364	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.635	0.365	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.634	0.366	0.000
E20-E35 Disorders of other endocrine glands	0.631	0.369	0.000
N20 Calculus of kidney and ureter	0.630	0.370	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.630	0.370	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.630	0.370	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.630	0.370	0.000
E89.5 Postprocedural testicular hypofunction	0.630	0.370	0.000
E89.4 Postprocedural ovarian failure	0.630	0.370	0.000
E89.3 Postprocedural hypopituitarism	0.630	0.370	0.000
E89.1 Postprocedural hypoinsulinaemia	0.630	0.370	0.000
H44 Disorders of globe	0.630	0.370	0.000
N18.0 End-stage renal disease	0.630	0.370	0.000
I00-I02 Acute rheumatic fever	0.629	0.371	0.000
H74.0 Tympanosclerosis	0.628	0.372	0.000
S32.01 Fracture of lumbar vertebra (open)	0.628	0.372	0.000
D50.1 Sideropenic dysphagia	0.627	0.373	0.000
E11.3 With ophthalmic complications	0.626	0.374	0.000
E88 Other metabolic disorders	0.625	0.374	0.000
S40-S49 Injuries to the shoulder and upper arm	0.625	0.375	0.000
O00 Ectopic pregnancy	0.624	0.376	0.000
S52.7 Multiple fractures of forearm	0.624	0.376	0.000
S79 Other and unspecified injuries of hip and thigh	0.624	0.376	0.000
D55-D59 Haemolytic anaemias	0.624	0.376	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.624	0.376	0.000
I10 Essential (primary) hypertension	0.623	0.377	0.000
I73.0 Raynaud's syndrome	0.622	0.378	0.000
N25 Disorders resulting from impaired renal tubular function	0.622	0.378	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.622	0.378	0.000
F34.1 Dysthymia	0.622	0.378	0.000
F99-F99 Unspecified mental disorder	0.621	0.378	0.000
H50.2 Vertical strabismus	0.621	0.379	0.000
S06.5 Traumatic subdural haemorrhage	0.621	0.379	0.000
H31 Other disorders of choroid	0.621	0.379	0.000
H61 Other disorders of external ear	0.621	0.379	0.000
H51 Other disorders of binocular movement	0.620	0.379	0.000
I74.5 Embolism and thrombosis of iliac artery	0.620	0.380	0.000
S91 Open wound of ankle and foot	0.618	0.381	0.000
S99.9 Unspecified injury of ankle and foot	0.618	0.382	0.000
O84 Multiple delivery	0.618	0.382	0.000
O83 Other assisted single delivery	0.618	0.382	0.000
S92.9 Fracture of foot, unspecified	0.618	0.382	0.000
S92.7 Multiple fractures of foot	0.618	0.382	0.000
S92.5 Fracture of other toe	0.618	0.382	0.000
S92.4 Fracture of great toe	0.618	0.382	0.000
S92.2 Fracture of other tarsal bone(s)	0.618	0.382	0.000
S92.1 Fracture of talus	0.618	0.382	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.618	0.382	0.000
O28 Abnormal findings on antenatal screening of mother	0.617	0.383	0.000
S81.8 Open wound of other parts of lower leg	0.616	0.383	0.000
F32.0 Mild depressive episode	0.616	0.384	0.000
J98 Other respiratory disorders	0.615	0.385	0.000
I46 Cardiac arrest	0.615	0.385	0.000
N30.3 Trigonitis	0.615	0.385	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.614	0.386	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.612	0.387	0.000
H04.1 Other disorders of lachrymal gland	0.612	0.388	0.000
S90.8 Other superficial injuries of ankle and foot	0.612	0.388	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.611	0.389	0.000
N34 Urethritis and urethral syndrome	0.611	0.389	0.000
H01.0 Blepharitis	0.610	0.390	0.000
H66.4 Suppurative otitis media, unspecified	0.609	0.391	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.609	0.391	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.609	0.391	0.000
H66.0 Acute suppurative otitis media	0.609	0.391	0.000
S06.01 Concussion (with open intracranial wound)	0.609	0.391	0.000
S51 Open wound of forearm	0.609	0.391	0.000
F80 Specific developmental disorders of speech and language	0.609	0.391	0.000
G36 Other acute disseminated demyelination	0.609	0.391	0.000
O60-O75 Complications of labour and delivery	0.609	0.391	0.000
H50.0 Convergent concomitant strabismus	0.609	0.391	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.608	0.392	0.000
S00.5 Superficial injury of lip and oral cavity	0.608	0.392	0.000
H65 Nonsuppurative otitis media	0.607	0.393	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.606	0.394	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.606	0.394	0.000
N18.5 Chronic kidney disease, stage 5	0.605	0.395	0.000
H36.0 Diabetic retinopathy	0.605	0.395	0.000
H66.3 Other chronic suppurative otitis media	0.604	0.396	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.604	0.396	0.000
F28 Other nonorganic psychotic disorders	0.603	0.396	0.000
F24 Induced delusional disorder	0.603	0.396	0.000
F21 Schizotypal disorder	0.603	0.396	0.000
N36 Other disorders of urethra	0.603	0.396	0.000
H69.9 Eustachian tube disorder, unspecified	0.602	0.398	0.000
N28.8 Other specified disorders of kidney and ureter	0.602	0.398	0.000
N05 Unspecified nephritic syndrome	0.600	0.400	0.000
N28.1 Cyst of kidney, acquired	0.600	0.400	0.000
E89.2 Postprocedural hypoparathyroidism	0.600	0.400	0.000
S70 Superficial injury of hip and thigh	0.600	0.400	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.599	0.401	0.000
F20.9 Schizophrenia, unspecified	0.599	0.401	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.598	0.402	0.000
S50.0 Contusion of elbow	0.597	0.403	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.597	0.403	0.000
T17.2 Foreign body in pharynx	0.596	0.403	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.595	0.405	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.595	0.405	0.000
G83 Other paralytic syndromes	0.595	0.405	0.000
S32.40 Fracture of acetabulum (closed)	0.594	0.406	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.594	0.406	0.000
G72 Other myopathies	0.593	0.407	0.000
T56 Toxic effect of metals	0.593	0.407	0.000
H18.2 Other corneal oedema	0.592	0.408	0.000
I13 Hypertensive heart and renal disease	0.592	0.408	0.000
F84 Pervasive developmental disorders	0.592	0.408	0.000
E40-E46 Malnutrition	0.591	0.409	0.000
I49.3 Ventricular premature depolarisation	0.591	0.409	0.000
S06.3 Focal brain injury	0.591	0.409	0.000
I51.6 Cardiovascular disease, unspecified	0.590	0.410	0.000
H34 Retinal vascular occlusions	0.590	0.410	0.000
H16 Keratitis	0.589	0.411	0.000
N19 Unspecified renal failure	0.588	0.412	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.587	0.413	0.000
N20.0 Calculus of kidney	0.587	0.413	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.586	0.414	0.000
S52.9 Fracture of forearm, part unspecified	0.586	0.414	0.000
S52.4 Fracture of shafts of both ulna and radius	0.586	0.414	0.000
S52.3 Fracture of shaft of radius	0.586	0.414	0.000
S52.2 Fracture of shaft of ulna	0.586	0.414	0.000
N32.0 Bladder-neck obstruction	0.586	0.414	0.000
T66-T78 Other and unspecified effects of external causes	0.585	0.414	0.001
G09 Sequelae of inflammatory diseases of central nervous system	0.585	0.415	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.585	0.415	0.000
G70 Myasthenia gravis and other myoneural disorders	0.584	0.416	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.584	0.416	0.000
I51.7 Cardiomegaly	0.583	0.417	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.582	0.418	0.000
S92.3 Fracture of metatarsal bone	0.582	0.418	0.000
S92.01 Fracture of calcaneus (open)	0.582	0.418	0.000
T19 Foreign body in genito-urinary tract	0.581	0.419	0.000
T15 Foreign body on external eye	0.581	0.419	0.000
T16 Foreign body in ear	0.581	0.419	0.000
S00.4 Superficial injury of ear	0.581	0.419	0.000
H49 Paralytic strabismus	0.580	0.419	0.000
G51 Facial nerve disorders	0.580	0.420	0.000
H46 Optic neuritis	0.580	0.420	0.000
N37 Urethral disorders in diseases classified elsewhere	0.580	0.420	0.000
N33 Bladder disorders in diseases classified elsewhere	0.580	0.420	0.000
S81.9 Open wound of lower leg, part unspecified	0.580	0.420	0.000
T21 Burn and corrosion of trunk	0.579	0.421	0.000
D52 Folate deficiency anaemia	0.578	0.422	0.000
I34 Nonrheumatic mitral valve disorders	0.578	0.422	0.000
O82.8 Other single delivery by Caesarean section	0.577	0.423	0.000
O82.2 Delivery by Caesarean hysterectomy	0.577	0.423	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations