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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9994162
log Bayes Factor = 12.3674
Chromosome 4   position 110,715,473  (GRCh37) Explore rs9994162 on Ensembl!
Variant rs9994162 is part of Cluster X0134

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.998 0.002 0.000
I20 Angina pectoris
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
I20.9 Angina pectoris, unspecified
0.992 0.008 0.000
I26 Pulmonary embolism
0.991 0.009 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.988 0.012 0.000
I51 Complications and ill-defined descriptions of heart disease
0.987 0.013 0.000
I21 Acute myocardial infarction
0.986 0.014 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.986 0.014 0.000
I25.1 Atherosclerotic heart disease
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.984 0.016 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.977 0.023 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.977 0.023 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.976 0.024 0.000
C34 Malignant neoplasm of bronchus and lung
0.966 0.034 0.000
I34 Nonrheumatic mitral valve disorders
0.964 0.036 0.000
I51.7 Cardiomegaly
0.964 0.036 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.962 0.038 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.960 0.040 0.000
C80 Malignant neoplasm without specification of site
0.960 0.040 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.960 0.040 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.956 0.044 0.000
S00-S09 Injuries to the head
0.948 0.052 0.000
T81 Complications of procedures, not elsewhere classified
0.945 0.055 0.000
D69 Purpura and other haemorrhagic conditions
0.942 0.058 0.000
Chapter V Mental and behavioural disorders
0.941 0.059 0.000
I34.0 Mitral (valve) insufficiency
0.939 0.061 0.000
C34.9 Bronchus or lung, unspecified
0.939 0.061 0.000
I27 Other pulmonary heart diseases
0.938 0.062 0.000
I24 Other acute ischaemic heart diseases
0.937 0.063 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.936 0.064 0.000
M23 Internal derangement of knee
0.927 0.073 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.924 0.076 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.923 0.077 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.921 0.079 0.000
I44 Atrioventricular and left bundle-branch block
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.910 0.090 0.000
C80.9 Malignant neoplasm, unspecified
0.908 0.092 0.000
M40-M43 Deforming dorsopathies
0.907 0.093 0.000
M24 Other specific joint derangements
0.906 0.094 0.000
D69.6 Thrombocytopenia, unspecified
0.904 0.096 0.000
C15-C26 Malignant neoplasms of digestive organs
0.900 0.100 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.899 0.101 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.899 0.101 0.000
I42 Cardiomyopathy
0.897 0.103 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.890 0.110 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.888 0.112 0.000
I25.5 Ischaemic cardiomyopathy
0.884 0.116 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.883 0.117 0.000
C32 Malignant neoplasm of larynx
0.882 0.118 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.881 0.119 0.000
Y44 Agents primarily affecting blood constituents
0.878 0.122 0.000
D68 Other coagulation defects
0.874 0.125 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.873 0.126 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.873 0.127 0.000
S20-S29 Injuries to the thorax
0.871 0.129 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.870 0.130 0.000
C77.2 Intra-abdominal lymph nodes
0.870 0.130 0.000
I38 Endocarditis, valve unspecified
0.862 0.138 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.861 0.139 0.000
C34.3 Lower lobe, bronchus or lung
0.855 0.145 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.855 0.145 0.000
I27.0 Primary pulmonary hypertension
0.853 0.147 0.000
I37 Pulmonary valve disorders
0.851 0.149 0.000
C77.0 Lymph nodes of head, face and neck
0.851 0.149 0.000
I20.0 Unstable angina
0.850 0.150 0.000
M35 Other systemic involvement of connective tissue
0.850 0.150 0.000
C18 Malignant neoplasm of colon
0.849 0.151 0.000
I44.1 Atrioventricular block, second degree
0.847 0.153 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.846 0.154 0.000
S10-S19 Injuries to the neck
0.840 0.160 0.000
C77.1 Intrathoracic lymph nodes
0.839 0.161 0.000
I51.9 Heart disease, unspecified
0.838 0.161 0.000
C77.9 Lymph node, unspecified
0.838 0.162 0.000
I25.2 Old myocardial infarction
0.836 0.164 0.000
C79 Secondary malignant neoplasm of other sites
0.826 0.174 0.000
C78.7 Secondary malignant neoplasm of liver
0.825 0.175 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.824 0.176 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.824 0.176 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.819 0.181 0.000
I44.0 Atrioventricular block, first degree
0.816 0.184 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.812 0.188 0.000
Y83.4 Other reconstructive surgery
0.811 0.189 0.000
S06 Intracranial injury
0.810 0.190 0.000
I05-I09 Chronic rheumatic heart diseases
0.810 0.190 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.809 0.191 0.000
M41 Scoliosis
0.806 0.194 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.805 0.194 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.805 0.195 0.000
I27.2 Other secondary pulmonary hypertension
0.804 0.196 0.000
M65-M68 Disorders of synovium and tendon
0.804 0.196 0.000
S60-S69 Injuries to the wrist and hand
0.803 0.197 0.000
Y44.2 Anticoagulants
0.802 0.198 0.000
F80-F89 Disorders of psychological development
0.802 0.198 0.000
I21.9 Acute myocardial infarction, unspecified
0.801 0.199 0.000
I20.1 Angina pectoris with documented spasm
0.800 0.200 0.000
C18.7 Sigmoid colon
0.800 0.200 0.000
I25.3 Aneurysm of heart
0.797 0.203 0.000
S02 Fracture of skull and facial bones
0.796 0.204 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.795 0.205 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.795 0.205 0.000
M91-M94 Chondropathies
0.795 0.205 0.000
M21 Other acquired deformities of limbs
0.794 0.206 0.000
I51.8 Other ill-defined heart diseases
0.789 0.211 0.000
M80-M85 Disorders of bone density and structure
0.784 0.216 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.782 0.218 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.782 0.218 0.000
D68.2 Hereditary deficiency of other clotting factors
0.781 0.219 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.778 0.221 0.000
W50-W64 Exposure to animate mechanical forces
0.778 0.222 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.775 0.225 0.000
Y52 Agents primarily affecting the cardiovascular system
0.774 0.226 0.000
T86 Failure and rejection of transplanted organs and tissues
0.774 0.226 0.000
Y48 Anaesthetics and therapeutic gases
0.773 0.227 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.772 0.228 0.000
S09 Other and unspecified injuries of head
0.771 0.229 0.000
M24.1 Other articular cartilage disorders
0.770 0.230 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.768 0.232 0.000
M34 Systemic sclerosis
0.767 0.233 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.767 0.233 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.765 0.235 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.764 0.236 0.000
V40-V49 Car occupant injured in transport accident
0.763 0.237 0.000
C78.2 Secondary malignant neoplasm of pleura
0.759 0.241 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.758 0.242 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.757 0.243 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.756 0.244 0.000
M43 Other deforming dorsopathies
0.754 0.246 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.754 0.246 0.000
M35.3 Polymyalgia rheumatica
0.753 0.247 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.753 0.247 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.752 0.248 0.000
I42.9 Cardiomyopathy, unspecified
0.751 0.249 0.000
T66-T78 Other and unspecified effects of external causes
0.749 0.251 0.000
Y40 Systemic antibiotics
0.748 0.251 0.000
C01 Malignant neoplasm of base of tongue
0.747 0.253 0.000
I37.1 Pulmonary valve insufficiency
0.746 0.254 0.000
T79-T79 Certain early complications of trauma
0.741 0.259 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.741 0.259 0.000
C83.3 Large cell (diffuse)
0.740 0.260 0.000
F99-F99 Unspecified mental disorder
0.737 0.263 0.000
S00 Superficial injury of head
0.736 0.264 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.734 0.265 0.000
M20 Acquired deformities of fingers and toes
0.733 0.267 0.000
F03 Unspecified dementia
0.733 0.267 0.000
M41.9 Scoliosis, unspecified
0.733 0.267 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.732 0.268 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.731 0.269 0.000
S32 Fracture of lumbar spine and pelvis
0.730 0.270 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.729 0.271 0.000
X50-X57 Overexertion, travel and privation
0.728 0.272 0.000
C32.1 Supraglottis
0.727 0.273 0.000
Q60-Q64 Congenital malformations of the urinary system
0.727 0.273 0.000
C07 Malignant neoplasm of parotid gland
0.725 0.275 0.000
V80-V89 Other land transport accidents
0.725 0.275 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.724 0.276 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.724 0.276 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.723 0.277 0.000
Chapter XXII Codes for special purposes
0.722 0.278 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.722 0.278 0.000
Y83.6 Removal of other organ (partial) (total)
0.722 0.278 0.000
C25 Malignant neoplasm of pancreas
0.719 0.281 0.000
T90 Sequelae of injuries of head
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
I07 Rheumatic tricuspid valve diseases
0.716 0.284 0.000
S01 Open wound of head
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
I28 Other diseases of pulmonary vessels
0.715 0.284 0.000
I25.6 Silent myocardial ischaemia
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.714 0.286 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.714 0.286 0.000
C32.9 Larynx, unspecified
0.714 0.286 0.000
I22 Subsequent myocardial infarction
0.713 0.287 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.713 0.287 0.000
T91 Sequelae of injuries of neck and trunk
0.712 0.288 0.000
T92 Sequelae of injuries of upper limb
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
F80 Specific developmental disorders of speech and language
0.711 0.289 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.711 0.289 0.000
I47 Paroxysmal tachycardia
0.711 0.289 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.711 0.289 0.000
M23.8 Other internal derangements of knee
0.710 0.290 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.710 0.290 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.708 0.292 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.708 0.292 0.000
C31 Malignant neoplasm of accessory sinuses
0.708 0.292 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.708 0.292 0.000
C37 Malignant neoplasm of thymus
0.708 0.292 0.000
C33 Malignant neoplasm of trachea
0.708 0.292 0.000
C34.2 Middle lobe, bronchus or lung
0.708 0.292 0.000
I51.6 Cardiovascular disease, unspecified
0.707 0.293 0.000
I51.5 Myocardial degeneration
0.707 0.293 0.000
I51.4 Myocarditis, unspecified
0.707 0.293 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.707 0.293 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.707 0.293 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.707 0.293 0.000
I51.0 Cardiac septal defect, acquired
0.707 0.293 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.707 0.293 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.707 0.293 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.707 0.293 0.000
M24.0 Loose body in joint
0.707 0.293 0.000
D80-D89 Certain disorders involving the immune mechanism
0.706 0.294 0.000
Y59 Other and unspecified vaccines and biological substances
0.705 0.295 0.000
Y58 Bacterial vaccines
0.705 0.295 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.705 0.295 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.705 0.295 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.705 0.295 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.705 0.295 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
I34.1 Mitral (valve) prolapse
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
C78.0 Secondary malignant neoplasm of lung
0.702 0.297 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.702 0.298 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.298 0.000
M33 Dermatopolymyositis
0.701 0.298 0.000
M32 Systemic lupus erythematosus
0.701 0.298 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.298 0.000
C32.0 Glottis
0.701 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.300 0.000
Q50-Q56 Congenital malformations of genital organs
0.700 0.300 0.000
S29 Other and unspecified injuries of thorax
0.700 0.300 0.000
D68.6 Other Thrombophilia
0.699 0.301 0.000
I42.0 Dilated cardiomyopathy
0.698 0.302 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.698 0.302 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.697 0.303 0.000
Y83.0 Surgical operation with transplant of whole organ
0.697 0.303 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.696 0.303 0.000
I30 Acute pericarditis
0.696 0.304 0.000
C18.9 Colon, unspecified
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
S61 Open wound of wrist and hand
0.694 0.306 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.693 0.307 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.693 0.307 0.000
C34.8 Overlapping lesion of bronchus and lung
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.692 0.307 0.000
Q80-Q89 Other congenital malformations
0.691 0.308 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.691 0.309 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.691 0.309 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.691 0.309 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.691 0.309 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.689 0.311 0.000
I44.3 Other and unspecified atrioventricular block
0.689 0.311 0.000
Y60.0 During surgical operation
0.688 0.312 0.000
C17 Malignant neoplasm of small intestine
0.687 0.313 0.000
I24.8 Other forms of acute ischaemic heart disease
0.687 0.313 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.686 0.314 0.000
D55-D59 Haemolytic anaemias
0.686 0.314 0.000
D67 Hereditary factor IX deficiency
0.686 0.314 0.000
D66 Hereditary factor VIII deficiency
0.686 0.314 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.686 0.314 0.000
M50-M54 Other dorsopathies
0.685 0.315 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.684 0.316 0.000
I31 Other diseases of pericardium
0.682 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.681 0.319 0.000
C16 Malignant neoplasm of stomach
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.680 0.320 0.000
S07 Crushing injury of head
0.680 0.320 0.000
S05 Injury of eye and orbit
0.680 0.320 0.000
S04 Injury of cranial nerves
0.680 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.320 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.679 0.321 0.000
Chapter I Certain infectious and parasitic diseases
0.678 0.322 0.000
D68.8 Other specified coagulation defects
0.678 0.322 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.678 0.322 0.000
M24.2 Disorder of ligament
0.678 0.322 0.000
T81.9 Unspecified complication of procedure
0.677 0.323 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.677 0.323 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.677 0.323 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.677 0.323 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.677 0.323 0.000
Y83.3 Surgical operation with formation of external stoma
0.677 0.323 0.000
Y83.5 Amputation of limb(s)
0.676 0.324 0.000
D69.9 Haemorrhagic condition, unspecified
0.676 0.324 0.000
D69.8 Other specified haemorrhagic conditions
0.676 0.324 0.000
D69.5 Secondary thrombocytopenia
0.676 0.324 0.000
D69.4 Other primary thrombocytopenia
0.676 0.324 0.000
D69.2 Other nonthrombocytopenic purpura
0.676 0.324 0.000
D69.1 Qualitative platelet defects
0.676 0.324 0.000
D69.0 Allergic purpura
0.676 0.324 0.000
F10.0 Acute intoxication
0.675 0.325 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.675 0.325 0.000
F70-F79 Mental retardation
0.675 0.325 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.675 0.325 0.000
M23.5 Chronic instability of knee
0.674 0.326 0.000
C18.1 Appendix
0.674 0.326 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.673 0.326 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.673 0.326 0.000
I27.9 Pulmonary heart disease, unspecified
0.672 0.327 0.000
I27.8 Other specified pulmonary heart diseases
0.672 0.327 0.000
I27.1 Kyphoscoliotic heart disease
0.672 0.327 0.000
I24.1 Dressler's syndrome
0.672 0.328 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.672 0.328 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.671 0.329 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.671 0.329 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.671 0.329 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.671 0.329 0.000
S27 Injury of other and unspecified intrathoracic organs
0.669 0.331 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
Y83.8 Other surgical procedures
0.667 0.333 0.000
C34.0 Main bronchus
0.667 0.333 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.666 0.334 0.000
I33 Acute and subacute endocarditis
0.665 0.334 0.000
M23.9 Internal derangement of knee, unspecified
0.664 0.335 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.664 0.335 0.000
M23.1 Discoid meniscus (congenital)
0.664 0.335 0.000
M23.0 Cystic meniscus
0.664 0.335 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.664 0.336 0.000
M99 Biomechanical lesions, not elsewhere classified
0.663 0.337 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.661 0.339 0.000
Y42.7 Androgens and anabolic congeners
0.661 0.339 0.000
C92 Myeloid leukaemia
0.660 0.339 0.000
S00.8 Superficial injury of other parts of head
0.660 0.340 0.000
Y83.9 Surgical procedure, unspecified
0.659 0.341 0.000
C77.5 Intrapelvic lymph nodes
0.658 0.342 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.656 0.344 0.000
S01.3 Open wound of ear
0.656 0.344 0.000
I42.8 Other cardiomyopathies
0.655 0.344 0.000
F10.2 Dependence syndrome
0.655 0.345 0.000
I44.6 Other and unspecified fascicular block
0.655 0.345 0.000
I44.5 Left posterior fascicular block
0.655 0.345 0.000
I44.4 Left anterior fascicular block
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.655 0.345 0.000
S02.1 Fracture of base of skull
0.654 0.346 0.000
V20-V29 Motorcycle rider injured in transport accident
0.653 0.347 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.653 0.347 0.000
C18.2 Ascending colon
0.652 0.348 0.000
M42 Spinal osteochondrosis
0.650 0.349 0.000
M40 Kyphosis and lordosis
0.650 0.349 0.000
I42.2 Other hypertrophic cardiomyopathy
0.650 0.350 0.000
M24.9 Joint derangement, unspecified
0.650 0.350 0.000
M24.7 Protrusio acetabuli
0.650 0.350 0.000
M24.6 Ankylosis of joint
0.650 0.350 0.000
M24.5 Contracture of joint
0.650 0.350 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.650 0.350 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.649 0.351 0.000
I07.1 Tricuspid insufficiency
0.649 0.351 0.000
C02.9 Tongue, unspecified
0.648 0.352 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.647 0.353 0.000
F80.1 Expressive language disorder
0.646 0.354 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.646 0.354 0.000
S20 Superficial injury of thorax
0.646 0.354 0.000
W20-W49 Exposure to inanimate mechanical forces
0.646 0.354 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.646 0.354 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.645 0.354 0.000
C23 Malignant neoplasm of gallbladder
0.645 0.354 0.000
C21 Malignant neoplasm of anus and anal canal
0.645 0.355 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.645 0.355 0.000
C13 Malignant neoplasm of hypopharynx
0.645 0.355 0.000
C11 Malignant neoplasm of nasopharynx
0.645 0.355 0.000
C10 Malignant neoplasm of oropharynx
0.645 0.355 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.645 0.355 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.645 0.355 0.000
C05 Malignant neoplasm of palate
0.645 0.355 0.000
C04 Malignant neoplasm of floor of mouth
0.645 0.355 0.000
C03 Malignant neoplasm of gum
0.645 0.355 0.000
C00 Malignant neoplasm of lip
0.645 0.355 0.000
C12 Malignant neoplasm of pyriform sinus
0.645 0.355 0.000
S09.9 Unspecified injury of head
0.644 0.356 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.643 0.357 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.643 0.357 0.000
I42.6 Alcoholic cardiomyopathy
0.643 0.357 0.000
I42.5 Other restrictive cardiomyopathy
0.643 0.357 0.000
I42.4 Endocardial fibroelastosis
0.643 0.357 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.643 0.357 0.000
M25 Other joint disorders, not elsewhere classified
0.643 0.357 0.000
M05-M14 Inflammatory polyarthropathies
0.643 0.357 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.641 0.359 0.000
S19 Other and unspecified injuries of neck
0.641 0.359 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.640 0.360 0.000
S02.3 Fracture of orbital floor
0.639 0.361 0.000
Y42.5 Other oestrogens and progestogens
0.638 0.361 0.000
T98 Sequelae of other and unspecified effects of external causes
0.638 0.361 0.000
T95 Sequelae of burns, corrosions and frostbite
0.638 0.361 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.638 0.361 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.638 0.361 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.638 0.361 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.638 0.362 0.000
Y45.0 Opioids and related analgesics
0.637 0.363 0.000
S10 Superficial injury of neck
0.636 0.364 0.000
S70-S79 Injuries to the hip and thigh
0.636 0.364 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.635 0.365 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.635 0.365 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.633 0.367 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.633 0.367 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.633 0.367 0.000
M96.5 Postradiation scoliosis
0.633 0.367 0.000
M96.4 Postsurgical lordosis
0.633 0.367 0.000
M96.3 Postlaminectomy kyphosis
0.633 0.367 0.000
M96.2 Postradiation kyphosis
0.633 0.367 0.000
F43 Reaction to severe stress, and adjustment disorders
0.633 0.367 0.000
C32.8 Overlapping lesion of larynx
0.632 0.368 0.000
C32.3 Laryngeal cartilage
0.632 0.368 0.000
C32.2 Subglottis
0.632 0.368 0.000
S32.5 Fracture of pubis
0.631 0.369 0.000
F60-F69 Disorders of adult personality and behaviour
0.631 0.369 0.000
S06.4 Epidural haemorrhage
0.631 0.369 0.000
M65 Synovitis and tenosynovitis
0.631 0.369 0.000
T86.0 Bone-marrow transplant rejection
0.631 0.369 0.000
M84 Disorders of continuity of bone
0.630 0.370 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.630 0.370 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.629 0.370 0.000
Y44.7 Plasma substitutes
0.629 0.370 0.000
Y44.6 Natural blood and blood products
0.629 0.370 0.000
Y44.5 Thrombolytic drugs
0.629 0.370 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.629 0.370 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.629 0.370 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.629 0.370 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.629 0.370 0.000
M93 Other osteochondropathies
0.629 0.371 0.000
M85 Other disorders of bone density and structure
0.629 0.371 0.000
I20.8 Other forms of angina pectoris
0.629 0.371 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.628 0.372 0.000
Q00-Q07 Congenital malformations of the nervous system
0.627 0.372 0.000
T21 Burn and corrosion of trunk
0.627 0.373 0.000
M21.2 Flexion deformity
0.627 0.373 0.000
D68.5 Primary Thrombophilia
0.627 0.373 0.000
D68.4 Acquired coagulation factor deficiency
0.627 0.373 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.627 0.373 0.000
D68.1 Hereditary factor XI deficiency
0.627 0.373 0.000
D68.0 Von Willebrand's disease
0.627 0.373 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.626 0.374 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.626 0.374 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.626 0.374 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.626 0.374 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.626 0.374 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.626 0.374 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.626 0.374 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.626 0.374 0.000
Y51.0 Anticholinesterase agents
0.626 0.374 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.626 0.374 0.000
M67 Other disorders of synovium and tendon
0.626 0.374 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.625 0.375 0.000
S26 Injury of heart
0.625 0.375 0.000
S25 Injury of blood vessels of thorax
0.625 0.375 0.000
S24 Injury of nerves and spinal cord at thorax level
0.625 0.375 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.625 0.375 0.000
S21 Open wound of thorax
0.625 0.375 0.000
M45-M49 Spondylopathies
0.625 0.375 0.000
S64 Injury of nerves at wrist and hand level
0.624 0.376 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.624 0.376 0.000
Y65 Other misadventures during surgical and medical care
0.624 0.376 0.000
Y64 Contaminated medical or biological substances
0.624 0.376 0.000
Y63 Failure in dosage during surgical and medical care
0.624 0.376 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.624 0.376 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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