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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0101
log Bayes Factor = 45.9023
contains 7 variants:
rs2335077
lBF = 7.489
Chr 1 : 107,573,565
rs78371551
lBF = 5.546
Chr 2 : 12,631,328
rs76138999
lBF = 6.409
Chr 5 : 102,029,219
rs77375314
lBF = 6.861
Chr 7 : 136,121,062
rs12823357
lBF = 6.086
Chr12 : 55,473,859
rs11638390
lBF = 6.155
Chr15 : 50,782,703
rs12978748
lBF = 5.986
Chr19 : 52,296,815
What are variant clusters?
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M17.9 Gonarthrosis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M17 Gonarthrosis [arthrosis of knee]
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
1.000 0.000 0.000
M24 Other specific joint derangements
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.999 0.001 0.000
M17.0 Primary gonarthrosis, bilateral
0.999 0.001 0.000
M15 Polyarthrosis
0.999 0.001 0.000
M21 Other acquired deformities of limbs
0.998 0.002 0.000
M46 Other inflammatory spondylopathies
0.996 0.004 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
M85 Other disorders of bone density and structure
0.994 0.006 0.000
M60-M63 Disorders of muscles
0.993 0.007 0.000
M84 Disorders of continuity of bone
0.991 0.009 0.000
M86-M90 Other osteopathies
0.990 0.010 0.000
Y52 Agents primarily affecting the cardiovascular system
0.989 0.011 0.000
M23 Internal derangement of knee
0.989 0.011 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.988 0.012 0.000
M40-M43 Deforming dorsopathies
0.988 0.012 0.000
M48 Other spondylopathies
0.987 0.013 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.985 0.015 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.984 0.016 0.000
M85.8 Other specified disorders of bone density and structure
0.982 0.018 0.000
M43 Other deforming dorsopathies
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.981 0.019 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.979 0.021 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.978 0.022 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.976 0.024 0.000
M62 Other disorders of muscle
0.976 0.024 0.000
M86 Osteomyelitis
0.973 0.027 0.000
M43.1 Spondylolisthesis
0.971 0.029 0.000
M24.5 Contracture of joint
0.969 0.031 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.967 0.033 0.000
Y49.5 Other antipsychotics and neuroleptics
0.966 0.034 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.964 0.036 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.964 0.036 0.000
M48.0 Spinal stenosis
0.964 0.036 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.963 0.037 0.000
M84.0 Malunion of fracture
0.961 0.039 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.960 0.040 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.959 0.041 0.000
M87 Osteonecrosis
0.957 0.043 0.000
M48.09 Spinal stenosis (Site unspecified)
0.957 0.043 0.000
W50-W64 Exposure to animate mechanical forces
0.956 0.044 0.000
M47 Spondylosis
0.955 0.045 0.000
M81 Osteoporosis without pathological fracture
0.953 0.047 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.952 0.048 0.000
M46.4 Discitis, unspecified
0.942 0.058 0.000
M21.2 Flexion deformity
0.940 0.060 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.940 0.060 0.000
M25.8 Other specified joint disorders
0.939 0.061 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.937 0.063 0.000
M47.1 Other spondylosis with myelopathy
0.936 0.064 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.936 0.064 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.934 0.066 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.928 0.072 0.000
M24.2 Disorder of ligament
0.927 0.073 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.921 0.079 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.921 0.079 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.920 0.080 0.000
M81.9 Osteoporosis, unspecified
0.916 0.084 0.000
M87.2 Osteonecrosis due to previous trauma
0.915 0.085 0.000
M60 Myositis
0.914 0.086 0.000
M24.54 Contracture of joint (Hand)
0.914 0.086 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.913 0.087 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.912 0.088 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.910 0.090 0.000
M23.4 Loose body in knee
0.906 0.094 0.000
M25.0 Haemarthrosis
0.906 0.094 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.905 0.095 0.000
M17.5 Other secondary gonarthrosis
0.904 0.096 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.904 0.096 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.901 0.099 0.000
M62.8 Other specified disorders of muscle
0.897 0.103 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.893 0.107 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.893 0.107 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.892 0.108 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.891 0.109 0.000
W20-W49 Exposure to inanimate mechanical forces
0.890 0.110 0.000
V40-V49 Car occupant injured in transport accident
0.889 0.111 0.000
M21.7 Unequal limb length (acquired)
0.886 0.114 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.886 0.114 0.000
M33 Dermatopolymyositis
0.885 0.115 0.000
M24.6 Ankylosis of joint
0.883 0.117 0.000
M15.8 Other polyarthrosis
0.882 0.118 0.000
M23.3 Other meniscus derangements
0.882 0.118 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.882 0.118 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.881 0.119 0.000
M86.6 Other chronic osteomyelitis
0.880 0.120 0.000
M24.51 Contracture of joint (Shoulder region)
0.879 0.121 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.878 0.122 0.000
W75-W84 Other accidental threats to breathing
0.877 0.123 0.000
V98-V99 Other and unspecified transport accidents
0.876 0.124 0.000
W00-W19 Falls
0.874 0.126 0.000
M84.02 Malunion of fracture (Upper arm)
0.873 0.127 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.871 0.129 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.870 0.130 0.000
M86.9 Osteomyelitis, unspecified
0.866 0.134 0.000
X49.9 Unspecified place
0.865 0.135 0.000
M23.9 Internal derangement of knee, unspecified
0.865 0.135 0.000
M48.8 Other specified spondylopathies
0.865 0.135 0.000
X50-X57 Overexertion, travel and privation
0.865 0.135 0.000
M15.3 Secondary multiple arthrosis
0.864 0.136 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.864 0.136 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.864 0.136 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.862 0.138 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.861 0.139 0.000
M21.0 Valgus deformity, not elsewhere classified
0.860 0.140 0.000
M25.83 Other specified joint disorders (Forearm)
0.859 0.141 0.000
M23.8 Other internal derangements of knee
0.854 0.146 0.000
M21.27 Flexion deformity (Ankle and foot)
0.852 0.148 0.000
Y48 Anaesthetics and therapeutic gases
0.852 0.148 0.000
M25.06 Haemarthrosis (Lower leg)
0.852 0.148 0.000
M15.1 Heberden's nodes (with arthropathy)
0.851 0.149 0.000
M15.4 Erosive (osteo)arthrosis
0.848 0.151 0.000
M43.6 Torticollis
0.848 0.152 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.845 0.155 0.000
Y49.2 Other and unspecified antidepressants
0.844 0.156 0.000
Z96.6 Presence of orthopaedic joint implants
0.844 0.156 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.840 0.160 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.840 0.160 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.840 0.160 0.000
M85.6 Other cyst of bone
0.840 0.160 0.000
M25.88 Other specified joint disorders (Other)
0.839 0.161 0.000
M65-M68 Disorders of synovium and tendon
0.837 0.163 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.831 0.169 0.000
M24.23 Disorder of ligament (Forearm)
0.830 0.170 0.000
M15.0 Primary generalised (osteo)arthrosis
0.829 0.171 0.000
W94 Exposure to high and low air pressure and changes in air pressure
0.829 0.171 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.829 0.171 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.826 0.174 0.000
W11 Fall on and from ladder
0.822 0.178 0.000
X00-X09 Exposure to smoke, fire and flames
0.820 0.180 0.000
V10-V19 Pedal cyclist injured in transport accident
0.820 0.180 0.000
Y47.1 Benzodiazepines
0.818 0.182 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.815 0.185 0.000
M84.8 Other disorders of continuity of bone
0.815 0.185 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.811 0.189 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.811 0.189 0.000
M84.4 Pathological fracture, not elsewhere classified
0.809 0.191 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.808 0.192 0.000
M23.43 Loose body in knee-Med lig/oth men
0.808 0.192 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.807 0.193 0.000
V20-V29 Motorcycle rider injured in transport accident
0.807 0.193 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.806 0.194 0.000
Y48.3 Local anaesthetics
0.806 0.194 0.000
M84.04 Malunion of fracture (Hand)
0.805 0.195 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.805 0.195 0.000
M24.28 Disorder of ligament (Other)
0.804 0.196 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.804 0.196 0.000
W49.9 Unspecified place
0.803 0.197 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.803 0.197 0.000
M00-M03 Infectious arthropathies
0.802 0.198 0.000
M32 Systemic lupus erythematosus
0.802 0.198 0.000
M85.9 Disorder of bone density and structure, unspecified
0.801 0.199 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.801 0.199 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.800 0.200 0.000
M24.7 Protrusio acetabuli
0.800 0.200 0.000
M21.26 Flexion deformity (Lower leg)
0.800 0.200 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.799 0.201 0.000
M60.0 Infective myositis
0.799 0.201 0.000
W49.0 Home
0.799 0.201 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.797 0.203 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.797 0.203 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.797 0.203 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.794 0.206 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.794 0.206 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.793 0.207 0.000
Y58 Bacterial vaccines
0.793 0.207 0.000
V99 Unspecified transport accident
0.792 0.208 0.000
M06.3 Rheumatoid nodule
0.791 0.209 0.000
Y10-Y34 Event of undetermined intent
0.791 0.209 0.000
M66 Spontaneous rupture of synovium and tendon
0.790 0.210 0.000
M48.04 Spinal stenosis (Thoracic region)
0.787 0.213 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.786 0.214 0.000
M25.3 Other instability of joint
0.786 0.214 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.784 0.216 0.000
M84.3 Stress fracture, not elsewhere classified
0.784 0.216 0.000
Y40 Systemic antibiotics
0.784 0.216 0.000
M43.0 Spondylolysis
0.784 0.216 0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)
0.784 0.216 0.000
M06.0 Seronegative rheumatoid arthritis
0.784 0.216 0.000
W20 Struck by thrown, projected or falling object
0.783 0.217 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.783 0.217 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.781 0.219 0.000
M84.01 Malunion of fracture (Shoulder region)
0.780 0.220 0.000
W79 Inhalation and ingestion of food causing obstruction of respiratory tract
0.780 0.220 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.778 0.222 0.000
M86.8 Other osteomyelitis
0.778 0.222 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.777 0.223 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.776 0.224 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.776 0.224 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.774 0.226 0.000
M87.9 Osteonecrosis, unspecified
0.774 0.226 0.000
M81.2 Osteoporosis of disuse
0.774 0.226 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.772 0.228 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.772 0.228 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.772 0.228 0.000
V48 Car occupant injured in noncollision transport accident
0.772 0.228 0.000
M21.9 Acquired deformity of limb, unspecified
0.771 0.229 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.769 0.231 0.000
W14 Fall from tree
0.768 0.232 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.768 0.232 0.000
M47.2 Other spondylosis with radiculopathy
0.768 0.232 0.000
W87 Exposure to unspecified electric current
0.767 0.233 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.766 0.234 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.766 0.234 0.000
M08 Juvenile arthritis
0.765 0.235 0.000
W94.8 Other specified place
0.764 0.236 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.764 0.236 0.000
M47.9 Spondylosis, unspecified
0.764 0.236 0.000
M84.03 Malunion of fracture (Forearm)
0.764 0.236 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.763 0.237 0.000
M21.4 Flat foot [pes planus] (acquired)
0.763 0.237 0.000
M25.9 Joint disorder, unspecified
0.762 0.238 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.760 0.240 0.000
M86.1 Other acute osteomyelitis
0.759 0.241 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.759 0.241 0.000
M62.2 Ischaemic infarction of muscle
0.758 0.241 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.758 0.242 0.000
Y56.3 Emollients, demulcents and protectants
0.758 0.242 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.757 0.243 0.000
V01-V09 Pedestrian injured in transport accident
0.755 0.245 0.000
M21.76 Unequal limb length (acquired) (Lower leg)
0.754 0.245 0.000
W07 Fall involving chair
0.754 0.246 0.000
M21.22 Flexion deformity (Upper arm)
0.753 0.247 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.752 0.248 0.000
M84.06 Malunion of fracture (Lower leg)
0.752 0.248 0.000
M43.62 Torticollis-Cervical
0.752 0.248 0.000
M83 Adult osteomalacia
0.752 0.248 0.000
M84.2 Delayed union of fracture
0.752 0.248 0.000
M40 Kyphosis and lordosis
0.751 0.249 0.000
M60.9 Myositis, unspecified
0.751 0.249 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.751 0.249 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.750 0.250 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.749 0.251 0.000
M50-M54 Other dorsopathies
0.748 0.252 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.747 0.253 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.747 0.253 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.747 0.253 0.000
M62.84 Other specified disorders of muscle (Hand)
0.746 0.254 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.746 0.254 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.746 0.254 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.745 0.254 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.745 0.255 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.745 0.255 0.000
X30-X39 Exposure to forces of nature
0.745 0.255 0.000
M33.1 Other dermatomyositis
0.744 0.256 0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.743 0.257 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.743 0.257 0.000
M45 Ankylosing spondylitis
0.740 0.260 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.739 0.261 0.000
M06.4 Inflammatory polyarthropathy
0.739 0.261 0.000
W78 Inhalation of gastric contents
0.739 0.261 0.000
M33.2 Polymyositis
0.738 0.262 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.737 0.263 0.000
W51 Striking against or bumped into by another person
0.736 0.264 0.000
M06.8 Other specified rheumatoid arthritis
0.735 0.265 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.735 0.265 0.000
M87.8 Other osteonecrosis
0.734 0.266 0.000
M23.1 Discoid meniscus (congenital)
0.734 0.266 0.000
M43.9 Deforming dorsopathy, unspecified
0.732 0.268 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.732 0.268 0.000
W20.0 Home
0.732 0.268 0.000
V90-V94 Water transport accidents
0.730 0.270 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.730 0.270 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.730 0.270 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.729 0.271 0.000
M07 Psoriatic and enteropathic arthropathies
0.729 0.271 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.729 0.271 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.728 0.272 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.726 0.273 0.000
M12 Other specific arthropathies
0.726 0.274 0.000
M62.9 Disorder of muscle, unspecified
0.726 0.274 0.000
M84.08 Malunion of fracture (Other)
0.726 0.274 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.726 0.274 0.000
M85.2 Hyperostosis of skull
0.725 0.275 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.725 0.275 0.000
V44.5 Driver injured in traffic accident
0.725 0.275 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.725 0.275 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.724 0.276 0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)
0.721 0.279 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.721 0.279 0.000
M48.86 Other specified spondylopathies (Lumbar region)
0.720 0.280 0.000
W19 Unspecified fall
0.720 0.280 0.000
X51 Travel and motion
0.720 0.280 0.000
W13 Fall from, out of or through building or structure
0.720 0.280 0.000
M21.8 Other specified acquired deformities of limbs
0.719 0.281 0.000
M23.46 Loose body in knee-O/unsp lat men
0.718 0.282 0.000
V70-V79 Bus occupant injured in transport accident
0.718 0.282 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.718 0.282 0.000
Y40.9 Systemic antibiotic, unspecified
0.718 0.282 0.000
M66.2 Spontaneous rupture of extensor tendons
0.718 0.282 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M24.9 Joint derangement, unspecified
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M80 Osteoporosis with pathological fracture
0.717 0.283 0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.717 0.283 0.000
M05.0 Felty's syndrome
0.717 0.283 0.000
M05.1 Rheumatoid lung disease
0.717 0.283 0.000
M05.2 Rheumatoid vasculitis
0.717 0.283 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.717 0.283 0.000
M24.24 Disorder of ligament (Hand)
0.717 0.283 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.716 0.284 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.716 0.284 0.000
M25.82 Other specified joint disorders (Upper arm)
0.714 0.286 0.000
M46.0 Spinal enthesopathy
0.714 0.286 0.000
M46.5 Other infective spondylopathies
0.714 0.286 0.000
M46.8 Other specified inflammatory spondylopathies
0.714 0.286 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.714 0.286 0.000
M85.0 Fibrous dysplasia (monostotic)
0.713 0.287 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
M24.57 Contracture of joint (Ankle and foot)
0.713 0.287 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.713 0.287 0.000
M85.1 Skeletal fluorosis
0.713 0.287 0.000
M85.3 Osteitis condensans
0.713 0.287 0.000
M85.4 Solitary bone cyst
0.713 0.287 0.000
M85.5 Aneurysmal bone cyst
0.713 0.287 0.000
W55 Bitten or struck by other mammals
0.713 0.287 0.000
M61 Calcification and ossification of muscle
0.712 0.288 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.712 0.288 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.711 0.289 0.000
W79.2 School, other institution and public administrative area
0.711 0.289 0.000
M84.9 Disorder of continuity of bone, unspecified
0.710 0.290 0.000
W19.2 School, other institution and public administrative area
0.710 0.290 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.710 0.290 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.710 0.290 0.000
M24.66 Ankylosis of joint (Lower leg)
0.709 0.290 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.709 0.291 0.000
Y40.3 Macrolides
0.709 0.291 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.709 0.291 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.709 0.291 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.709 0.291 0.000
X50 Overexertion and strenuous or repetitive movements
0.709 0.291 0.000
M42 Spinal osteochondrosis
0.708 0.292 0.000
Y52.7 Peripheral vasodilators
0.708 0.292 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.707 0.293 0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites
0.707 0.293 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.707 0.293 0.000
M48.2 Kissing spine
0.707 0.293 0.000
M48.3 Traumatic spondylopathy
0.707 0.293 0.000
M48.4 Fatigue fracture of vertebra
0.707 0.293 0.000
W07.9 Unspecified place
0.707 0.293 0.000
M85.68 Other cyst of bone (Other)
0.707 0.293 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.707 0.293 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.706 0.294 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.706 0.294 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.706 0.294 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.706 0.294 0.000
Y49.7 Psychostimulants with abuse potential
0.706 0.294 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.706 0.294 0.000
Y49.9 Psychotropic drug, unspecified
0.706 0.294 0.000
M25.84 Other specified joint disorders (Hand)
0.705 0.295 0.000
V27.4 Driver injured in traffic accident
0.705 0.295 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.704 0.295 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.704 0.295 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.704 0.295 0.000
Y46.2 Hydantoin derivatives
0.704 0.296 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.704 0.296 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.704 0.296 0.000
M43.5 Other recurrent vertebral subluxation
0.704 0.296 0.000
M43.8 Other specified deforming dorsopathies
0.704 0.296 0.000
X41.9 Unspecified place
0.704 0.296 0.000
M25.1 Fistula of joint
0.703 0.297 0.000
M25.2 Flail joint
0.703 0.297 0.000
W45 Foreign body or object entering through skin
0.703 0.297 0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.701 0.298 0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.701 0.298 0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.701 0.298 0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.701 0.298 0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.701 0.298 0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.701 0.298 0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.701 0.298 0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.701 0.298 0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.701 0.298 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.700 0.299 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.700 0.300 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.700 0.300 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.700 0.300 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.700 0.300 0.000
M62.3 Immobility syndrome (paraplegic)
0.700 0.300 0.000
M62.4 Contracture of muscle
0.700 0.300 0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)
0.700 0.300 0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)
0.700 0.300 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.698 0.302 0.000
W11.5 Trade and service area
0.698 0.302 0.000
M86.0 Acute haematogenous osteomyelitis
0.698 0.302 0.000
M86.2 Subacute osteomyelitis
0.698 0.302 0.000
M86.3 Chronic multifocal osteomyelitis
0.698 0.302 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.698 0.302 0.000
M53 Other dorsopathies, not elsewhere classified
0.698 0.302 0.000
W11.6 Industrial and construction area
0.696 0.304 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.696 0.304 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.696 0.304 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.696 0.304 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.696 0.304 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.696 0.304 0.000
W50.2 School, other institution and public administrative area
0.696 0.304 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.695 0.305 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.695 0.305 0.000
M24.50 Contracture of joint (Multiple sites)
0.695 0.305 0.000
M24.52 Contracture of joint (Upper arm)
0.695 0.305 0.000
M24.53 Contracture of joint (Forearm)
0.695 0.305 0.000
M24.58 Contracture of joint (Other)
0.695 0.305 0.000
M24.59 Contracture of joint (Site unspecified)
0.695 0.305 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.694 0.306 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.694 0.306 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.694 0.306 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.694 0.306 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.694 0.306 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.694 0.306 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.694 0.306 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.693 0.307 0.000
W11.4 Street and highway
0.691 0.309 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.691 0.309 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.691 0.309 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.691 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.691 0.309 0.000
M84.00 Malunion of fracture (Multiple sites)
0.689 0.311 0.000
M84.09 Malunion of fracture (Site unspecified)
0.689 0.311 0.000
W50.9 Unspecified place
0.689 0.311 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.689 0.311 0.000
M62.0 Diastasis of muscle
0.688 0.312 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.688 0.312 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.688 0.312 0.000
X48 Accidental poisoning by and exposure to pesticides
0.688 0.312 0.000
M46.2 Osteomyelitis of vertebra
0.687 0.313 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.686 0.313 0.000
M87.1 Osteonecrosis due to drugs
0.686 0.313 0.000
M87.3 Other secondary osteonecrosis
0.686 0.313 0.000
W52 Crushed, pushed and stepped on by crowd or human stampede
0.686 0.314 0.000
W53 Bitten by rat
0.686 0.314 0.000
W54 Bitten or struck by dog
0.686 0.314 0.000
W56 Contact with marine animal
0.686 0.314 0.000
W58 Bitten or struck by crocodile or alligator
0.686 0.314 0.000
W59 Bitten or crushed by other reptiles
0.686 0.314 0.000
W21 Striking against or struck by sports equipment
0.686 0.314 0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)
0.685 0.315 0.000
M24.26 Disorder of ligament (Lower leg)
0.685 0.315 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.685 0.315 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.684 0.316 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.684 0.316 0.000
M81.1 Postoophorectomy osteoporosis
0.683 0.317 0.000
M81.5 Idiopathic osteoporosis
0.683 0.317 0.000
M81.6 Localised osteoporosis [Lequesne]
0.683 0.317 0.000
M81.8 Other osteoporosis
0.683 0.317 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.683 0.317 0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)
0.682 0.318 0.000
X45 Accidental poisoning by and exposure to alcohol
0.681 0.319 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.680 0.320 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.678 0.322 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.678 0.322 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.677 0.323 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.676 0.324 0.000
M25.33 Other instability of joint (Forearm)
0.676 0.324 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.676 0.324 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.676 0.324 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.676 0.324 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.676 0.324 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.676 0.324 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.676 0.324 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.675 0.325 0.000
V95-V97 Air and space transport accidents
0.674 0.326 0.000
M21.20 Flexion deformity (Multiple sites)
0.674 0.326 0.000
M21.21 Flexion deformity (Shoulder region)
0.674 0.326 0.000
M21.23 Flexion deformity (Forearm)
0.674 0.326 0.000
M21.28 Flexion deformity (Other)
0.674 0.326 0.000
M21.29 Flexion deformity (Site unspecified)
0.674 0.326 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.673 0.327 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.673 0.327 0.000
M48.9 Spondylopathy, unspecified
0.673 0.327 0.000
M90 Osteopathies in diseases classified elsewhere
0.672 0.328 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.672 0.328 0.000
M05.8 Other seropositive rheumatoid arthritis
0.671 0.328 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.671 0.329 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.671 0.329 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.671 0.329 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.671 0.329 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.671 0.329 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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