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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0284
log Bayes Factor = 192.532
contains 9 variants:
rs62328524
lBF = 13.170
Chr 4 : 161,682,941
rs75440732
lBF = 14.776
Chr 5 : 170,932,931
rs75737817
lBF = 15.480
Chr10 : 3,868,557
rs79215307
lBF = 13.012
Chr10 : 130,302,069
rs79476482
lBF = 14.933
Chr12 : 76,084,550
rs117019691
lBF = 21.558
Chr16 : 57,505,625
rs62076101
lBF = 21.813
Chr17 : 45,882,243
rs117131051
lBF = 12.836
Chr18 : 25,336,648
rs76602912
lBF = 13.837
Chr20 : 57,459,868
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
M47 Spondylosis
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
1.000 0.000 0.000
M47.9 Spondylosis, unspecified
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I71 Aortic aneurysm and dissection
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
1.000 0.000 0.000
H55-H59 Other disorders of eye and adnexa
1.000 0.000 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
1.000 0.000 0.000
M24 Other specific joint derangements
1.000 0.000 0.000
S01 Open wound of head
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
F10.0 Acute intoxication
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
S50-S59 Injuries to the elbow and forearm
0.999 0.001 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.999 0.001 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.999 0.001 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.999 0.001 0.000
H04 Disorders of lachrymal system
0.999 0.001 0.000
F60-F69 Disorders of adult personality and behaviour
0.999 0.001 0.000
F43 Reaction to severe stress, and adjustment disorders
0.999 0.001 0.000
M50 Cervical disk disorders
0.999 0.001 0.000
F17.2 Dependence syndrome
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.999 0.001 0.000
I20 Angina pectoris
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
I20.9 Angina pectoris, unspecified
0.999 0.001 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.999 0.001 0.000
F60 Specific personality disorders
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
M23 Internal derangement of knee
0.998 0.002 0.000
H10-H13 Disorders of conjunctiva
0.998 0.002 0.000
M25 Other joint disorders, not elsewhere classified
0.998 0.002 0.000
M79.8 Other specified soft tissue disorders
0.998 0.002 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.998 0.002 0.000
F41 Other anxiety disorders
0.998 0.002 0.000
H40-H42 Glaucoma
0.998 0.002 0.000
H18 Other disorders of cornea
0.997 0.003 0.000
I34 Nonrheumatic mitral valve disorders
0.997 0.003 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
H33 Retinal detachments and breaks
0.997 0.003 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.997 0.003 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.996 0.004 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.996 0.004 0.000
H40 Glaucoma
0.996 0.004 0.000
H11 Other disorders of conjunctiva
0.996 0.004 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.995 0.005 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.995 0.005 0.000
H57 Other disorders of eye and adnexa
0.995 0.005 0.000
F41.2 Mixed anxiety and depressive disorder
0.995 0.005 0.000
H65-H75 Diseases of middle ear and mastoid
0.994 0.006 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.994 0.006 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.994 0.006 0.000
G95 Other diseases of spinal cord
0.994 0.006 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
M25.8 Other specified joint disorders
0.993 0.007 0.000
F40 Phobic anxiety disorders
0.993 0.007 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.992 0.008 0.000
E16 Other disorders of pancreatic internal secretion
0.992 0.008 0.000
S00 Superficial injury of head
0.992 0.008 0.000
I05-I09 Chronic rheumatic heart diseases
0.992 0.008 0.000
M84 Disorders of continuity of bone
0.992 0.008 0.000
O60-O75 Complications of labour and delivery
0.992 0.008 0.000
F60.9 Personality disorder, unspecified
0.992 0.008 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.991 0.009 0.000
F33 Recurrent depressive disorder
0.991 0.009 0.000
S40-S49 Injuries to the shoulder and upper arm
0.991 0.009 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.990 0.010 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.990 0.010 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.990 0.010 0.000
I34.0 Mitral (valve) insufficiency
0.990 0.010 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.989 0.011 0.000
H65 Nonsuppurative otitis media
0.989 0.011 0.000
M79.6 Pain in limb
0.989 0.011 0.000
E16.2 Hypoglycaemia, unspecified
0.988 0.012 0.000
F40.2 Specific (isolated) phobias
0.988 0.012 0.000
M65-M68 Disorders of synovium and tendon
0.987 0.013 0.000
H18.8 Other specified disorders of cornea
0.986 0.014 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.986 0.014 0.000
H33.0 Retinal detachment with retinal break
0.986 0.014 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.985 0.015 0.000
S51 Open wound of forearm
0.985 0.015 0.000
W00-W19 Falls
0.985 0.015 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.985 0.015 0.000
I50 Heart failure
0.985 0.015 0.000
M50.1 Cervical disk disorder with radiculopathy
0.984 0.016 0.000
S20-S29 Injuries to the thorax
0.984 0.016 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.983 0.017 0.000
M46 Other inflammatory spondylopathies
0.982 0.018 0.000
I44 Atrioventricular and left bundle-branch block
0.982 0.018 0.000
H57.1 Ocular pain
0.982 0.018 0.000
O66 Other obstructed labour
0.981 0.019 0.000
G54 Nerve root and plexus disorders
0.981 0.019 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.981 0.019 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.981 0.019 0.000
M50.2 Other cervical disk displacement
0.980 0.020 0.000
T92 Sequelae of injuries of upper limb
0.980 0.020 0.000
F60.3 Emotionally unstable personality disorder
0.979 0.021 0.000
I72 Other aneurysm
0.979 0.021 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.979 0.021 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.979 0.021 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.979 0.021 0.000
H04.1 Other disorders of lachrymal gland
0.978 0.022 0.000
B35-B49 Mycoses
0.978 0.022 0.000
S90-S99 Injuries to the ankle and foot
0.977 0.023 0.000
Chapter XXI Factors influencing health status and contact with health services
0.977 0.023 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.977 0.023 0.000
H40.0 Glaucoma suspect
0.976 0.024 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.976 0.024 0.000
S30.1 Contusion of abdominal wall
0.976 0.024 0.000
E10-E14 Diabetes mellitus
0.976 0.024 0.000
M54 Dorsalgia
0.976 0.024 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.975 0.025 0.000
M65 Synovitis and tenosynovitis
0.975 0.025 0.000
F10.3 Withdrawal state
0.975 0.025 0.000
I25.2 Old myocardial infarction
0.974 0.026 0.000
H35 Other retinal disorders
0.974 0.026 0.000
S60 Superficial injury of wrist and hand
0.974 0.026 0.000
M79.1 Myalgia
0.973 0.027 0.000
I50.1 Left ventricular failure
0.973 0.027 0.000
F10.4 Withdrawal state with delirium
0.973 0.027 0.000
M79.69 Pain in limb (Site unspecified)
0.972 0.028 0.000
I05 Rheumatic mitral valve diseases
0.972 0.028 0.000
S70-S79 Injuries to the hip and thigh
0.971 0.029 0.000
H11.3 Conjunctival haemorrhage
0.971 0.029 0.000
M24.2 Disorder of ligament
0.971 0.029 0.000
X60-X84 Intentional self-harm
0.970 0.030 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.970 0.030 0.000
F43.2 Adjustment disorders
0.970 0.030 0.000
E11 Non-insulin-dependent diabetes mellitus
0.969 0.031 0.000
S50 Superficial injury of forearm
0.969 0.031 0.000
I44.0 Atrioventricular block, first degree
0.969 0.031 0.000
T93 Sequelae of injuries of lower limb
0.969 0.031 0.000
I22 Subsequent myocardial infarction
0.969 0.031 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.969 0.031 0.000
S51.0 Open wound of elbow
0.967 0.033 0.000
M47.2 Other spondylosis with radiculopathy
0.966 0.034 0.000
M48 Other spondylopathies
0.966 0.034 0.000
M21 Other acquired deformities of limbs
0.966 0.034 0.000
Z73 Problems related to life-management difficulty
0.966 0.034 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.965 0.035 0.000
F43.1 Posttraumatic stress disorder
0.965 0.035 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.964 0.036 0.000
L05 Pilonidal cyst
0.964 0.036 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.963 0.037 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.963 0.037 0.000
M47.1 Other spondylosis with myelopathy
0.962 0.038 0.000
T86 Failure and rejection of transplanted organs and tissues
0.962 0.038 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.962 0.038 0.000
H74 Other disorders of middle ear and mastoid
0.962 0.038 0.000
T42.4 Benzodiazepines
0.962 0.038 0.000
Y52 Agents primarily affecting the cardiovascular system
0.960 0.040 0.000
I45 Other conduction disorders
0.960 0.040 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.960 0.040 0.000
G90 Disorders of autonomic nervous system
0.959 0.041 0.000
J43 Emphysema
0.959 0.041 0.000
M25.86 Other specified joint disorders (Lower leg)
0.958 0.042 0.000
C71 Malignant neoplasm of brain
0.958 0.042 0.000
D48.1 Connective and other soft tissue
0.958 0.042 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.957 0.043 0.000
I49 Other cardiac arrhythmias
0.957 0.043 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.957 0.043 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.956 0.044 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.956 0.044 0.000
Y57 Other and unspecified drugs and medicaments
0.956 0.044 0.000
F43.0 Acute stress reaction
0.956 0.044 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.955 0.045 0.000
J00-J06 Acute upper respiratory infections
0.955 0.045 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.954 0.046 0.000
H55 Nystagmus and other irregular eye movements
0.954 0.046 0.000
M05-M14 Inflammatory polyarthropathies
0.953 0.047 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.953 0.047 0.000
F32 Depressive episode
0.952 0.048 0.000
M54.5 Low back pain
0.952 0.048 0.000
L05.0 Pilonidal cyst with abscess
0.951 0.049 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.950 0.050 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.950 0.050 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.950 0.050 0.000
F20 Schizophrenia
0.950 0.050 0.000
I20.1 Angina pectoris with documented spasm
0.949 0.051 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.948 0.052 0.000
S05 Injury of eye and orbit
0.947 0.053 0.000
G95.2 Cord compression, unspecified
0.946 0.054 0.000
E27 Other disorders of adrenal gland
0.946 0.054 0.000
H35.4 Peripheral retinal degeneration
0.945 0.055 0.000
G95.8 Other specified diseases of spinal cord
0.945 0.055 0.000
S67 Crushing injury of wrist and hand
0.944 0.056 0.000
L08 Other local infections of skin and subcutaneous tissue
0.943 0.057 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.943 0.057 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.942 0.058 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.942 0.058 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.941 0.059 0.000
I60-I69 Cerebrovascular diseases
0.941 0.059 0.000
M40-M43 Deforming dorsopathies
0.941 0.059 0.000
W50-W64 Exposure to animate mechanical forces
0.940 0.060 0.000
L50-L54 Urticaria and erythema
0.940 0.060 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.940 0.060 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.940 0.060 0.000
H40.8 Other glaucoma
0.939 0.061 0.000
S01.2 Open wound of nose
0.938 0.062 0.000
S01.9 Open wound of head, part unspecified
0.937 0.063 0.000
M85 Other disorders of bone density and structure
0.936 0.064 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.936 0.064 0.000
M25.3 Other instability of joint
0.935 0.065 0.000
H40.9 Glaucoma, unspecified
0.935 0.065 0.000
M54.56 Low back pain (Lumbar region)
0.934 0.066 0.000
M79.64 Pain in limb (Hand)
0.934 0.066 0.000
F25 Schizoaffective disorders
0.934 0.066 0.000
I47 Paroxysmal tachycardia
0.934 0.066 0.000
G70-G73 Diseases of myoneural junction and muscle
0.933 0.067 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.933 0.067 0.000
G93 Other disorders of brain
0.932 0.068 0.000
B15-B19 Viral hepatitis
0.931 0.069 0.000
S10-S19 Injuries to the neck
0.930 0.069 0.000
M10 Gout
0.929 0.071 0.000
H40.5 Glaucoma secondary to other eye disorders
0.927 0.073 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.927 0.073 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.927 0.073 0.000
S32 Fracture of lumbar spine and pelvis
0.926 0.074 0.000
C32 Malignant neoplasm of larynx
0.926 0.074 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.925 0.075 0.000
I71.0 Dissection of aorta [any part]
0.925 0.075 0.000
I51 Complications and ill-defined descriptions of heart disease
0.925 0.075 0.000
G30-G32 Other degenerative diseases of the nervous system
0.925 0.075 0.000
F31 Bipolar affective disorder
0.924 0.076 0.000
J90-J94 Other diseases of pleura
0.924 0.076 0.000
T40.4 Other synthetic narcotics
0.923 0.077 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.923 0.077 0.000
G58 Other mononeuropathies
0.923 0.077 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.923 0.077 0.000
M48.0 Spinal stenosis
0.922 0.078 0.000
M91-M94 Chondropathies
0.921 0.079 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.921 0.079 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.920 0.080 0.000
I21 Acute myocardial infarction
0.920 0.080 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.919 0.081 0.000
S70 Superficial injury of hip and thigh
0.919 0.081 0.000
I95 Hypotension
0.919 0.081 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.919 0.081 0.000
Y42.7 Androgens and anabolic congeners
0.918 0.082 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.918 0.082 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.918 0.082 0.000
G90.2 Horner's syndrome
0.918 0.082 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.918 0.082 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.918 0.082 0.000
G44 Other headache syndromes
0.917 0.083 0.000
Q23 Congenital malformations of aortic and mitral valves
0.917 0.083 0.000
I21.9 Acute myocardial infarction, unspecified
0.917 0.083 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.917 0.083 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.916 0.084 0.000
I36 Nonrheumatic tricuspid valve disorders
0.915 0.085 0.000
E11.4 With neurological complications
0.915 0.085 0.000
J43.9 Emphysema, unspecified
0.915 0.085 0.000
S01.3 Open wound of ear
0.914 0.086 0.000
I49.8 Other specified cardiac arrhythmias
0.914 0.086 0.000
S01.1 Open wound of eyelid and periocular area
0.914 0.086 0.000
S01.5 Open wound of lip and oral cavity
0.914 0.086 0.000
H60-H62 Diseases of external ear
0.913 0.087 0.000
S91 Open wound of ankle and foot
0.913 0.087 0.000
M79.60 Pain in limb (Multiple sites)
0.913 0.087 0.000
I08 Multiple valve diseases
0.912 0.088 0.000
M54.4 Lumbago with sciatica
0.912 0.088 0.000
S60.8 Other superficial injuries of wrist and hand
0.912 0.088 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.912 0.088 0.000
Y00-Y09 Assault
0.911 0.089 0.000
M10.9 Gout, unspecified
0.911 0.089 0.000
M50.0 Cervical disk disorder with myelopathy
0.910 0.090 0.000
Y44 Agents primarily affecting blood constituents
0.910 0.090 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.910 0.090 0.000
C64-C68 Malignant neoplasms of urinary tract
0.910 0.090 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.910 0.090 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.909 0.091 0.000
S52 Fracture of forearm
0.909 0.091 0.000
S00.5 Superficial injury of lip and oral cavity
0.908 0.092 0.000
Y54.3 Benzothiadiazine derivatives
0.907 0.093 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.907 0.093 0.000
T51 Toxic effect of alcohol
0.907 0.093 0.000
H04.4 Chronic inflammation of lachrymal passages
0.907 0.093 0.000
O85-O92 Complications predominantly related to the puerperium
0.907 0.093 0.000
I05.2 Mitral stenosis with insufficiency
0.906 0.094 0.000
H74.0 Tympanosclerosis
0.906 0.094 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.906 0.094 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.906 0.094 0.000
T40.2 Other opioids
0.905 0.095 0.000
M86-M90 Other osteopathies
0.905 0.095 0.000
G41 Status epilepticus
0.904 0.096 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.904 0.096 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.904 0.096 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.904 0.096 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.904 0.096 0.000
I60 Subarachnoid haemorrhage
0.903 0.097 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.902 0.098 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.902 0.098 0.000
E11.5 With peripheral circulatory complications
0.901 0.099 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.901 0.099 0.000
I05.0 Mitral stenosis
0.900 0.100 0.000
E29 Testicular dysfunction
0.900 0.100 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.900 0.100 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.900 0.100 0.000
S90 Superficial injury of ankle and foot
0.900 0.100 0.000
T93.1 Sequelae of fracture of femur
0.899 0.101 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.899 0.101 0.000
H35.9 Retinal disorder, unspecified
0.899 0.101 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.899 0.101 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.898 0.102 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.897 0.103 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.897 0.103 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.897 0.103 0.000
H90-H95 Other disorders of ear
0.896 0.104 0.000
I46 Cardiac arrest
0.896 0.104 0.000
H65.3 Chronic mucoid otitis media
0.895 0.105 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.895 0.105 0.000
M79.10 Myalgia (Multiple sites)
0.895 0.105 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.894 0.106 0.000
F25.9 Schizoaffective disorder, unspecified
0.894 0.106 0.000
G63.2 Diabetic polyneuropathy
0.894 0.106 0.000
I50.9 Heart failure, unspecified
0.893 0.107 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.893 0.107 0.000
I22.8 Subsequent myocardial infarction of other sites
0.893 0.107 0.000
M79.18 Myalgia (Other)
0.893 0.107 0.000
S29 Other and unspecified injuries of thorax
0.893 0.107 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.893 0.107 0.000
H05 Disorders of orbit
0.892 0.108 0.000
M43 Other deforming dorsopathies
0.892 0.108 0.000
H25-H28 Disorders of lens
0.892 0.108 0.000
H21 Other disorders of iris and ciliary body
0.892 0.108 0.000
S27 Injury of other and unspecified intrathoracic organs
0.892 0.108 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.892 0.108 0.000
S50.8 Other superficial injuries of forearm
0.891 0.109 0.000
I44.6 Other and unspecified fascicular block
0.891 0.109 0.000
Z73.3 Stress, not elsewhere classified
0.890 0.110 0.000
Z72 Problems related to lifestyle
0.890 0.110 0.000
I72.0 Aneurysm of carotid artery
0.890 0.110 0.000
I33 Acute and subacute endocarditis
0.889 0.111 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.889 0.111 0.000
Q80-Q89 Other congenital malformations
0.889 0.111 0.000
I45.6 Preexcitation syndrome
0.889 0.111 0.000
M24.5 Contracture of joint
0.888 0.112 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.888 0.112 0.000
E23 Hypofunction and other disorders of pituitary gland
0.888 0.112 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.888 0.112 0.000
S80-S89 Injuries to the knee and lower leg
0.887 0.113 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.887 0.113 0.000
M79.61 Pain in limb (Shoulder region)
0.887 0.113 0.000
H11.0 Pterygium
0.886 0.114 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.885 0.115 0.000
E24 Cushing's syndrome
0.885 0.115 0.000
T87 Complications peculiar to reattachment and amputation
0.885 0.115 0.000
Y57.5 X-ray contrast media
0.884 0.116 0.000
M71 Other bursopathies
0.884 0.116 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.884 0.116 0.000
Z76 Persons encountering health services in other circumstances
0.884 0.116 0.000
W13 Fall from, out of or through building or structure
0.884 0.116 0.000
S01.4 Open wound of cheek and temporomandibular area
0.883 0.117 0.000
L53 Other erythematous conditions
0.883 0.117 0.000
M54.50 Low back pain (Multiple sites in spine)
0.881 0.119 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.881 0.119 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.881 0.119 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.881 0.119 0.000
M15-M19 Arthrosis
0.881 0.119 0.000
H90 Conductive and sensorineural hearing loss
0.881 0.119 0.000
S72 Fracture of femur
0.881 0.119 0.000
M45 Ankylosing spondylitis
0.880 0.120 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.880 0.120 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.879 0.121 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.879 0.121 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.878 0.122 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.878 0.122 0.000
D68 Other coagulation defects
0.877 0.123 0.000
M54.1 Radiculopathy
0.876 0.124 0.000
G58.8 Other specified mononeuropathies
0.876 0.124 0.000
H33.5 Other retinal detachments
0.875 0.125 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.874 0.126 0.000
M25.37 Other instability of joint (Ankle and foot)
0.874 0.126 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.874 0.126 0.000
B35 Dermatophytosis
0.874 0.126 0.000
Q28 Other congenital malformations of circulatory system
0.873 0.127 0.000
Q23.1 Congenital insufficiency of aortic valve
0.873 0.127 0.000
F41.1 Generalised anxiety disorder
0.873 0.127 0.000
H61 Other disorders of external ear
0.873 0.127 0.000
M81 Osteoporosis without pathological fracture
0.873 0.127 0.000
D48.6 Breast
0.872 0.128 0.000
V40-V49 Car occupant injured in transport accident
0.872 0.128 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.871 0.129 0.000
K70 Alcoholic liver disease
0.871 0.129 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.871 0.129 0.000
X50-X57 Overexertion, travel and privation
0.871 0.129 0.000
S50.9 Superficial injury of forearm, unspecified
0.870 0.130 0.000
M79.2 Neuralgia and neuritis, unspecified
0.870 0.130 0.000
C71.2 Temporal lobe
0.870 0.130 0.000
S52.0 Fracture of upper end of ulna
0.870 0.130 0.000
H18.5 Hereditary corneal dystrophies
0.869 0.131 0.000
B37 Candidiasis
0.869 0.131 0.000
H57.8 Other specified disorders of eye and adnexa
0.869 0.131 0.000
M24.1 Other articular cartilage disorders
0.869 0.131 0.000
I47.2 Ventricular tachycardia
0.868 0.132 0.000
M43.0 Spondylolysis
0.868 0.132 0.000
T51.0 Ethanol
0.868 0.132 0.000
I25.5 Ischaemic cardiomyopathy
0.868 0.132 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.868 0.132 0.000
F20.9 Schizophrenia, unspecified
0.867 0.133 0.000
M85.8 Other specified disorders of bone density and structure
0.867 0.133 0.000
T90 Sequelae of injuries of head
0.866 0.134 0.000
M23.4 Loose body in knee
0.866 0.134 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.865 0.135 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.865 0.135 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.865 0.135 0.000
O73 Retained placenta and membranes, without haemorrhage
0.865 0.135 0.000
G96 Other disorders of central nervous system
0.864 0.136 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.864 0.136 0.000
F32.0 Mild depressive episode
0.863 0.137 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.862 0.138 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.862 0.138 0.000
S62 Fracture at wrist and hand level
0.862 0.138 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.862 0.138 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.861 0.139 0.000
I51.8 Other ill-defined heart diseases
0.861 0.139 0.000
T79-T79 Certain early complications of trauma
0.860 0.140 0.000
H53-H54 Visual disturbances and blindness
0.860 0.140 0.000
K70.3 Alcoholic cirrhosis of liver
0.860 0.140 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.859 0.141 0.000
I46.9 Cardiac arrest, unspecified
0.858 0.142 0.000
H16 Keratitis
0.858 0.142 0.000
K70-K77 Diseases of liver
0.858 0.142 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.858 0.142 0.000
X68.9 Unspecified place
0.857 0.143 0.000
D48.0 Bone and articular cartilage
0.856 0.144 0.000
E11.8 With unspecified complications
0.856 0.144 0.000
F20.0 Paranoid schizophrenia
0.856 0.144 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.856 0.144 0.000
E22 Hyperfunction of pituitary gland
0.855 0.145 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.855 0.145 0.000
C32.9 Larynx, unspecified
0.854 0.146 0.000
H11.8 Other specified disorders of conjunctiva
0.853 0.147 0.000
V80-V89 Other land transport accidents
0.853 0.147 0.000
M48.02 Spinal stenosis (Cervical region)
0.853 0.147 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.853 0.147 0.000
B44 Aspergillosis
0.852 0.148 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.852 0.148 0.000
B18 Chronic viral hepatitis
0.852 0.148 0.000
M80 Osteoporosis with pathological fracture
0.851 0.148 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.851 0.149 0.000
O61 Failed induction of labour
0.851 0.149 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.851 0.149 0.000
F42 Obsessive-compulsive disorder
0.851 0.149 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.850 0.150 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.850 0.150 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.850 0.150 0.000
B37.8 Candidiasis of other sites
0.850 0.150 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.850 0.150 0.000
T91 Sequelae of injuries of neck and trunk
0.850 0.150 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.850 0.150 0.000
S01.7 Multiple open wounds of head
0.849 0.151 0.000
I95.2 Hypotension due to drugs
0.849 0.151 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.849 0.151 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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