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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76602912
log Bayes Factor = 13.8371
Chromosome 20   position 57,459,868  (GRCh37) Explore rs76602912 on Ensembl!
Variant rs76602912 is part of Cluster X0284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
M47.9 Spondylosis, unspecified
0.995 0.005 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.007 0.993
M50-M54 Other dorsopathies
0.987 0.013 0.000
G90-G99 Other disorders of the nervous system
0.985 0.015 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.982 0.018 0.000
M50 Cervical disk disorders
0.978 0.022 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.969 0.031 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.968 0.032 0.000
Chapter V Mental and behavioural disorders
0.966 0.034 0.000
M48 Other spondylopathies
0.964 0.036 0.000
Chapter I Certain infectious and parasitic diseases
0.955 0.045 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.953 0.047 0.000
I71 Aortic aneurysm and dissection
0.944 0.056 0.000
I73 Other peripheral vascular diseases
0.943 0.057 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.941 0.059 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.934 0.066 0.000
M48.0 Spinal stenosis
0.932 0.068 0.000
I77 Other disorders of arteries and arterioles
0.926 0.074 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.922 0.078 0.000
I20-I25 Ischaemic heart diseases
0.921 0.079 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.918 0.082 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.913 0.087 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.912 0.088 0.000
M50.1 Cervical disk disorder with radiculopathy
0.911 0.089 0.000
M65-M68 Disorders of synovium and tendon
0.909 0.091 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.906 0.094 0.000
I73.9 Peripheral vascular disease, unspecified
0.906 0.094 0.000
M50.0 Cervical disk disorder with myelopathy
0.905 0.095 0.000
A00-A09 Intestinal infectious diseases
0.900 0.100 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.895 0.105 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.894 0.106 0.000
I10-I15 Hypertensive diseases
0.891 0.109 0.000
M40-M43 Deforming dorsopathies
0.891 0.109 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.890 0.110 0.000
I20 Angina pectoris
0.887 0.113 0.000
S00-S09 Injuries to the head
0.881 0.119 0.000
H90-H95 Other disorders of ear
0.880 0.120 0.000
I05-I09 Chronic rheumatic heart diseases
0.879 0.121 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.878 0.122 0.000
M46 Other inflammatory spondylopathies
0.875 0.125 0.000
G95 Other diseases of spinal cord
0.873 0.127 0.000
M45 Ankylosing spondylitis
0.869 0.131 0.000
S20-S29 Injuries to the thorax
0.869 0.131 0.000
Chapter X Diseases of the respiratory system
0.869 0.131 0.000
M80-M85 Disorders of bone density and structure
0.869 0.131 0.000
M65 Synovitis and tenosynovitis
0.868 0.132 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.867 0.133 0.000
M47.1 Other spondylosis with myelopathy
0.860 0.140 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.856 0.144 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.855 0.145 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.855 0.145 0.000
R41.0 Disorientation, unspecified
0.854 0.146 0.000
G56 Mononeuropathies of upper limb
0.854 0.146 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.853 0.147 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.852 0.148 0.000
F41 Other anxiety disorders
0.852 0.148 0.000
H90 Conductive and sensorineural hearing loss
0.852 0.148 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.852 0.148 0.000
M47.8 Other spondylosis
0.851 0.149 0.000
S40-S49 Injuries to the shoulder and upper arm
0.849 0.151 0.000
M50.3 Other cervical disk degeneration
0.848 0.152 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.846 0.154 0.000
G93 Other disorders of brain
0.843 0.157 0.000
Chapter VII Diseases of the eye and adnexa
0.842 0.158 0.000
F43 Reaction to severe stress, and adjustment disorders
0.840 0.160 0.000
Chapter XX External causes of morbidity and mortality
0.840 0.160 0.000
J40-J47 Chronic lower respiratory diseases
0.840 0.160 0.000
R02 Gangrene, not elsewhere classified
0.839 0.161 0.000
G57 Mononeuropathies of lower limb
0.838 0.162 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.838 0.162 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.838 0.162 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.838 0.162 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.838 0.162 0.000
I20.8 Other forms of angina pectoris
0.831 0.169 0.000
M51 Other intervertebral disk disorders
0.831 0.169 0.000
J44 Other chronic obstructive pulmonary disease
0.831 0.169 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.829 0.171 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.825 0.175 0.000
I72 Other aneurysm
0.825 0.175 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.822 0.178 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.822 0.178 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.821 0.179 0.000
H65-H75 Diseases of middle ear and mastoid
0.819 0.181 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.818 0.182 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.816 0.184 0.000
G90 Disorders of autonomic nervous system
0.814 0.186 0.000
H02 Other disorders of eyelid
0.813 0.187 0.000
G70-G73 Diseases of myoneural junction and muscle
0.813 0.187 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.810 0.190 0.000
I78 Diseases of capillaries
0.807 0.193 0.000
B35-B49 Mycoses
0.806 0.194 0.000
M70-M79 Other soft tissue disorders
0.806 0.194 0.000
S50-S59 Injuries to the elbow and forearm
0.805 0.195 0.000
J00-J06 Acute upper respiratory infections
0.804 0.196 0.000
R26 Abnormalities of gait and mobility
0.801 0.199 0.000
G56.2 Lesion of ulnar nerve
0.801 0.199 0.000
M91-M94 Chondropathies
0.800 0.200 0.000
F40 Phobic anxiety disorders
0.799 0.201 0.000
S01 Open wound of head
0.798 0.202 0.000
I20.9 Angina pectoris, unspecified
0.795 0.205 0.000
M85 Other disorders of bone density and structure
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.793 0.207 0.000
I77.1 Stricture of artery
0.790 0.210 0.000
A08 Viral and other specified intestinal infections
0.789 0.211 0.000
G30-G32 Other degenerative diseases of the nervous system
0.787 0.213 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.786 0.214 0.000
M43 Other deforming dorsopathies
0.786 0.214 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.786 0.214 0.000
S70-S79 Injuries to the hip and thigh
0.783 0.217 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.779 0.221 0.000
I77.2 Rupture of artery
0.778 0.222 0.000
H04 Disorders of lachrymal system
0.778 0.222 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.777 0.223 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.777 0.223 0.000
M50.2 Other cervical disk displacement
0.776 0.224 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.772 0.227 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.769 0.231 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.766 0.234 0.000
R29.6 Tendency to fall, not elsewhere classified
0.765 0.235 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.765 0.235 0.000
I77.6 Arteritis, unspecified
0.763 0.237 0.000
R07 Pain in throat and chest
0.761 0.239 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.761 0.239 0.000
H90.2 Conductive hearing loss, unspecified
0.760 0.240 0.000
I12 Hypertensive renal disease
0.755 0.245 0.000
I22 Subsequent myocardial infarction
0.755 0.245 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.754 0.246 0.000
G81 Hemiplegia
0.751 0.249 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.750 0.250 0.000
X60-X84 Intentional self-harm
0.749 0.251 0.000
R41.3 Other amnesia
0.749 0.251 0.000
I83 Varicose veins of lower extremities
0.170 0.251 0.580
M48.02 Spinal stenosis (Cervical region)
0.749 0.251 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.749 0.251 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.748 0.251 0.000
I10 Essential (primary) hypertension
0.746 0.254 0.000
S40 Superficial injury of shoulder and upper arm
0.743 0.257 0.000
G58 Other mononeuropathies
0.741 0.259 0.000
M65.3 Trigger finger
0.741 0.259 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.740 0.260 0.000
I08 Multiple valve diseases
0.740 0.260 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.739 0.261 0.000
I24 Other acute ischaemic heart diseases
0.738 0.262 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.737 0.263 0.000
G57.6 Lesion of plantar nerve
0.737 0.263 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.737 0.263 0.000
H80-H83 Diseases of inner ear
0.736 0.264 0.000
F43.2 Adjustment disorders
0.733 0.267 0.000
B02 Zoster [herpes zoster]
0.733 0.267 0.000
G95.2 Cord compression, unspecified
0.732 0.268 0.000
F17.2 Dependence syndrome
0.732 0.268 0.000
R25 Abnormal involuntary movements
0.732 0.268 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.732 0.268 0.000
M47.82 Other spondylosis (Cervical region)
0.731 0.269 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.731 0.269 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.730 0.269 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.730 0.270 0.000
I05 Rheumatic mitral valve diseases
0.730 0.270 0.000
S60-S69 Injuries to the wrist and hand
0.728 0.272 0.000
M47.2 Other spondylosis with radiculopathy
0.726 0.274 0.000
R07.0 Pain in throat
0.726 0.274 0.000
M53 Other dorsopathies, not elsewhere classified
0.725 0.274 0.000
F41.9 Anxiety disorder, unspecified
0.725 0.275 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.725 0.275 0.000
M85.8 Other specified disorders of bone density and structure
0.725 0.275 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.724 0.276 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.708 0.276 0.017
S50 Superficial injury of forearm
0.723 0.277 0.000
I74 Arterial embolism and thrombosis
0.722 0.278 0.000
H02.0 Entropion and trichiasis of eyelid
0.721 0.279 0.000
B99-B99 Other infectious diseases
0.720 0.280 0.000
M43.0 Spondylolysis
0.720 0.280 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.283 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.715 0.285 0.000
F99-F99 Unspecified mental disorder
0.713 0.287 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.713 0.287 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.713 0.287 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.713 0.287 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.713 0.287 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.713 0.287 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.713 0.287 0.000
T40.2 Other opioids
0.712 0.288 0.000
J06.9 Acute upper respiratory infection, unspecified
0.712 0.288 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.711 0.289 0.000
R03.1 Nonspecific low blood-pressure reading
0.711 0.289 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.711 0.289 0.000
H02.3 Blepharochalasis
0.711 0.289 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.711 0.289 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.711 0.289 0.000
H02.4 Ptosis of eyelid
0.710 0.289 0.000
M48.09 Spinal stenosis (Site unspecified)
0.709 0.290 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.709 0.291 0.000
A08.4 Viral intestinal infection, unspecified
0.709 0.291 0.000
B07 Viral warts
0.707 0.293 0.000
T91 Sequelae of injuries of neck and trunk
0.706 0.293 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.706 0.294 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.706 0.294 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.706 0.294 0.000
G92 Toxic encephalopathy
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.295 0.000
M48.06 Spinal stenosis (Lumbar region)
0.705 0.295 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.705 0.295 0.000
F41.1 Generalised anxiety disorder
0.705 0.295 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.704 0.296 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.704 0.296 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.704 0.296 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.704 0.296 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.704 0.296 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
T36 Poisoning by systemic antibiotics
0.704 0.296 0.000
G54 Nerve root and plexus disorders
0.703 0.296 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.703 0.297 0.000
G93.3 Postviral fatigue syndrome
0.702 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.702 0.298 0.000
H04.1 Other disorders of lachrymal gland
0.702 0.298 0.000
M41 Scoliosis
0.702 0.298 0.000
M50.9 Cervical disk disorder, unspecified
0.701 0.299 0.000
M50.8 Other cervical disk disorders
0.701 0.299 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.701 0.299 0.000
I72.0 Aneurysm of carotid artery
0.701 0.299 0.000
M51.2 Other specified intervertebral disk displacement
0.700 0.300 0.000
T40.4 Other synthetic narcotics
0.699 0.301 0.000
G95.8 Other specified diseases of spinal cord
0.699 0.301 0.000
T43.2 Other and unspecified antidepressants
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.302 0.000
F40.2 Specific (isolated) phobias
0.698 0.302 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.697 0.303 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.696 0.304 0.000
F60-F69 Disorders of adult personality and behaviour
0.696 0.304 0.000
I60-I69 Cerebrovascular diseases
0.695 0.305 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.694 0.306 0.000
G52 Disorders of other cranial nerves
0.694 0.306 0.000
M86-M90 Other osteopathies
0.692 0.307 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.307 0.000
F80-F89 Disorders of psychological development
0.692 0.307 0.000
F70-F79 Mental retardation
0.692 0.307 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.692 0.308 0.000
M48.9 Spondylopathy, unspecified
0.691 0.308 0.000
M48.8 Other specified spondylopathies
0.691 0.308 0.000
M48.4 Fatigue fracture of vertebra
0.691 0.308 0.000
M48.3 Traumatic spondylopathy
0.691 0.308 0.000
M48.2 Kissing spine
0.691 0.308 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.691 0.308 0.000
S05 Injury of eye and orbit
0.691 0.309 0.000
J46 Status asthmaticus
0.691 0.309 0.000
Chapter XXII Codes for special purposes
0.690 0.310 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.690 0.310 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.690 0.310 0.000
H65 Nonsuppurative otitis media
0.689 0.311 0.000
S01.9 Open wound of head, part unspecified
0.688 0.312 0.000
M15-M19 Arthrosis
0.688 0.312 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.686 0.313 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.685 0.315 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.315 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
B50-B64 Protozoal diseases
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.685 0.315 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.315 0.000
A75-A79 Rickettsioses
0.685 0.315 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.315 0.000
A65-A69 Other spirochaetal diseases
0.685 0.315 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.315 0.000
A15-A19 Tuberculosis
0.685 0.315 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.684 0.316 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.684 0.316 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.684 0.316 0.000
S22.4 Multiple fractures of ribs
0.684 0.316 0.000
H92 Otalgia and effusion of ear
0.684 0.316 0.000
F42 Obsessive-compulsive disorder
0.683 0.317 0.000
S01.4 Open wound of cheek and temporomandibular area
0.681 0.318 0.000
F43.0 Acute stress reaction
0.681 0.319 0.000
G96 Other disorders of central nervous system
0.680 0.320 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.679 0.321 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
G71 Primary disorders of muscles
0.677 0.323 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.677 0.323 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.677 0.323 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.677 0.323 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.677 0.323 0.000
I73.8 Other specified peripheral vascular diseases
0.676 0.324 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.676 0.324 0.000
R45 Symptoms and signs involving emotional state
0.676 0.324 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.676 0.324 0.000
A80-A89 Viral infections of the central nervous system
0.676 0.324 0.000
G81.9 Hemiplegia, unspecified
0.676 0.324 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.675 0.325 0.000
F48 Other neurotic disorders
0.675 0.325 0.000
F44 Dissociative [conversion] disorders
0.675 0.325 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.675 0.325 0.000
S00 Superficial injury of head
0.673 0.327 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.673 0.327 0.000
M43.02 Spondylolysis (Cervical region)
0.672 0.328 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.672 0.328 0.000
G95.9 Disease of spinal cord, unspecified
0.671 0.328 0.000
F45 Somatoform disorders
0.670 0.329 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.670 0.330 0.000
I78.1 Naevus, nonneoplastic
0.670 0.330 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.670 0.330 0.000
H90.0 Conductive hearing loss, bilateral
0.670 0.330 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.669 0.330 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.669 0.330 0.000
I20.1 Angina pectoris with documented spasm
0.669 0.331 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.668 0.331 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.668 0.331 0.000
M48.04 Spinal stenosis (Thoracic region)
0.668 0.331 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.668 0.331 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.668 0.331 0.000
M72 Fibroblastic disorders
0.668 0.332 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
M84 Disorders of continuity of bone
0.667 0.333 0.000
I71.0 Dissection of aorta [any part]
0.667 0.333 0.000
J43 Emphysema
0.667 0.333 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.666 0.334 0.000
G51 Facial nerve disorders
0.666 0.334 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.664 0.336 0.000
I73.0 Raynaud's syndrome
0.664 0.336 0.000
R27 Other lack of coordination
0.664 0.336 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.664 0.336 0.000
I77.8 Other specified disorders of arteries and arterioles
0.664 0.336 0.000
I77.5 Necrosis of artery
0.664 0.336 0.000
I77.4 Coeliac artery compression syndrome
0.664 0.336 0.000
I77.3 Arterial fibromuscular dysplasia
0.664 0.336 0.000
I77.0 Arteriovenous fistula, acquired
0.664 0.336 0.000
B25-B34 Other viral diseases
0.664 0.336 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.663 0.336 0.000
G40-G47 Episodic and paroxysmal disorders
0.663 0.337 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.662 0.338 0.000
G50 Disorders of trigeminal nerve
0.662 0.338 0.000
M70.6 Trochanteric bursitis
0.660 0.340 0.000
I23 Certain current complications following acute myocardial infarction
0.660 0.340 0.000
J03 Acute tonsillitis
0.659 0.341 0.000
T90 Sequelae of injuries of head
0.658 0.342 0.000
G93.2 Benign intracranial hypertension
0.658 0.342 0.000
R26.0 Ataxic gait
0.657 0.343 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.657 0.343 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.657 0.343 0.000
S01.2 Open wound of nose
0.656 0.344 0.000
I63 Cerebral infarction
0.655 0.345 0.000
F41.2 Mixed anxiety and depressive disorder
0.655 0.345 0.000
R46 Symptoms and signs involving appearance and behaviour
0.654 0.345 0.000
R43 Disturbances of smell and taste
0.654 0.345 0.000
I70 Atherosclerosis
0.654 0.346 0.000
S92 Fracture of foot, except ankle
0.653 0.347 0.000
H01 Other inflammation of eyelid
0.653 0.347 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.652 0.348 0.000
M66 Spontaneous rupture of synovium and tendon
0.652 0.348 0.000
V80-V89 Other land transport accidents
0.652 0.348 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.651 0.349 0.000
B44 Aspergillosis
0.651 0.349 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.650 0.350 0.000
S27 Injury of other and unspecified intrathoracic organs
0.650 0.350 0.000
M65.34 Trigger finger-Hand
0.650 0.350 0.000
B37 Candidiasis
0.650 0.350 0.000
R44.3 Hallucinations, unspecified
0.650 0.350 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.649 0.350 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.649 0.350 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.649 0.350 0.000
I99 Other and unspecified disorders of circulatory system
0.648 0.352 0.000
A07 Other protozoal intestinal diseases
0.645 0.355 0.000
A06 Amoebiasis
0.645 0.355 0.000
A05 Other bacterial foodborne intoxications
0.645 0.355 0.000
A03 Shigellosis
0.645 0.355 0.000
A02 Other Salmonella infections
0.645 0.355 0.000
A01 Typhoid and paratyphoid fevers
0.645 0.355 0.000
A00 Cholera
0.645 0.355 0.000
T39.1 4-Aminophenol derivatives
0.645 0.355 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.644 0.356 0.000
W50-W64 Exposure to animate mechanical forces
0.643 0.356 0.000
M92 Other juvenile osteochondrosis
0.643 0.357 0.000
G90.2 Horner's syndrome
0.642 0.357 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.642 0.358 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.642 0.358 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.641 0.359 0.000
R47-R49 Symptoms and signs involving speech and voice
0.641 0.359 0.000
L05 Pilonidal cyst
0.641 0.359 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.640 0.360 0.000
H72 Perforation of tympanic membrane
0.639 0.361 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.639 0.361 0.000
I15 Secondary hypertension
0.639 0.361 0.000
I13 Hypertensive heart and renal disease
0.639 0.361 0.000
I11 Hypertensive heart disease
0.639 0.361 0.000
M42 Spinal osteochondrosis
0.638 0.361 0.000
M40 Kyphosis and lordosis
0.638 0.361 0.000
H00 Hordeolum and chalazion
0.638 0.362 0.000
H60-H62 Diseases of external ear
0.638 0.362 0.000
R41.2 Retrograde amnesia
0.638 0.362 0.000
R41.1 Anterograde amnesia
0.638 0.362 0.000
R01 Cardiac murmurs and other cardiac sounds
0.638 0.362 0.000
X62.9 Unspecified place
0.638 0.362 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.638 0.362 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.636 0.364 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.635 0.365 0.000
B02.9 Zoster without complication
0.635 0.365 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.634 0.366 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.634 0.366 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.634 0.366 0.000
J60-J70 Lung diseases due to external agents
0.633 0.367 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.632 0.368 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.632 0.368 0.000
S08 Traumatic amputation of part of head
0.632 0.368 0.000
S07 Crushing injury of head
0.632 0.368 0.000
S04 Injury of cranial nerves
0.632 0.368 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.632 0.368 0.000
I12.0 Hypertensive renal disease with renal failure
0.631 0.369 0.000
R71 Abnormality of red blood cells
0.631 0.369 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.631 0.369 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.631 0.369 0.000
I09 Other rheumatic heart diseases
0.630 0.369 0.000
I06 Rheumatic aortic valve diseases
0.630 0.369 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.630 0.370 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.630 0.370 0.000
G93.9 Disorder of brain, unspecified
0.629 0.371 0.000
M46.8 Other specified inflammatory spondylopathies
0.628 0.372 0.000
M46.5 Other infective spondylopathies
0.628 0.372 0.000
M46.4 Discitis, unspecified
0.628 0.372 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.628 0.372 0.000
M46.2 Osteomyelitis of vertebra
0.628 0.372 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.628 0.372 0.000
M46.0 Spinal enthesopathy
0.628 0.372 0.000
M05-M14 Inflammatory polyarthropathies
0.627 0.373 0.000
H02.1 Ectropion of eyelid
0.627 0.373 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.626 0.373 0.000
G95.1 Vascular myelopathies
0.626 0.374 0.000
G95.0 Syringomyelia and syringobulbia
0.626 0.374 0.000
S20 Superficial injury of thorax
0.625 0.374 0.000
S22.40 Multiple fractures of ribs (closed)
0.625 0.374 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.625 0.375 0.000
I07 Rheumatic tricuspid valve diseases
0.624 0.376 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.623 0.377 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.623 0.377 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.623 0.377 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.623 0.377 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.623 0.377 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.623 0.377 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.623 0.377 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.623 0.377 0.000
S29 Other and unspecified injuries of thorax
0.623 0.377 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.623 0.377 0.000
S26 Injury of heart
0.623 0.377 0.000
S25 Injury of blood vessels of thorax
0.623 0.377 0.000
S24 Injury of nerves and spinal cord at thorax level
0.623 0.377 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.623 0.377 0.000
S21 Open wound of thorax
0.623 0.377 0.000
M83 Adult osteomalacia
0.623 0.377 0.000
M82 Osteoporosis in diseases classified elsewhere
0.623 0.377 0.000
M65.8 Other synovitis and tenosynovitis
0.622 0.378 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.622 0.378 0.000
M65.2 Calcific tendinitis
0.622 0.378 0.000
M65.1 Other infective (teno)synovitis
0.622 0.378 0.000
M65.0 Abscess of tendon sheath
0.622 0.378 0.000
G57.8 Other mononeuropathies of lower limb
0.622 0.378 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.621 0.378 0.000
Q60-Q64 Congenital malformations of the urinary system
0.621 0.378 0.000
M85.6 Other cyst of bone
0.621 0.379 0.000
G82 Paraplegia and tetraplegia
0.620 0.380 0.000
M18 Arthrosis of first carpometacarpal joint
0.620 0.380 0.000
S79 Other and unspecified injuries of hip and thigh
0.619 0.381 0.000
O60-O75 Complications of labour and delivery
0.619 0.381 0.000
R25.2 Cramp and spasm
0.619 0.381 0.000
S06 Intracranial injury
0.618 0.381 0.000
S50.8 Other superficial injuries of forearm
0.618 0.382 0.000
M51.9 Intervertebral disk disorder, unspecified
0.617 0.383 0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.617 0.383 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.617 0.383 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.617 0.383 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.617 0.383 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.617 0.383 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.617 0.383 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.617 0.383 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.617 0.383 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.617 0.383 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.616 0.384 0.000
R44.1 Visual hallucinations
0.615 0.384 0.000
M47.86 Other spondylosis (Lumbar region)
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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