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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0294
log Bayes Factor = 25.2869
contains 2 variants:
rs17615906
lBF = 13.069
Chr 5 : 128,018,413
rs11773624
lBF = 6.073
Chr 7 : 12,023,864
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M24 Other specific joint derangements
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
I50.0 Congestive heart failure
0.998 0.002 0.000
I47 Paroxysmal tachycardia
0.997 0.003 0.000
M10 Gout
0.995 0.005 0.000
I44 Atrioventricular and left bundle-branch block
0.995 0.005 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.993 0.007 0.000
I50.1 Left ventricular failure
0.992 0.008 0.000
M10.9 Gout, unspecified
0.992 0.008 0.000
I44.7 Left bundle-branch block, unspecified
0.991 0.009 0.000
I34 Nonrheumatic mitral valve disorders
0.990 0.010 0.000
M10.99 Gout, unspecified (Site unspecified)
0.990 0.010 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
I47.2 Ventricular tachycardia
0.984 0.016 0.000
I42 Cardiomyopathy
0.984 0.016 0.000
I60-I69 Cerebrovascular diseases
0.980 0.020 0.000
M84 Disorders of continuity of bone
0.975 0.025 0.000
I20 Angina pectoris
0.973 0.027 0.000
I47.1 Supraventricular tachycardia
0.973 0.027 0.000
I25.2 Old myocardial infarction
0.969 0.031 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.963 0.037 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.963 0.037 0.000
M70-M79 Other soft tissue disorders
0.956 0.044 0.000
M24.0 Loose body in joint
0.953 0.047 0.000
I34.0 Mitral (valve) insufficiency
0.945 0.055 0.000
M40-M43 Deforming dorsopathies
0.943 0.057 0.000
I11 Hypertensive heart disease
0.937 0.063 0.000
I25.5 Ischaemic cardiomyopathy
0.933 0.067 0.000
M24.5 Contracture of joint
0.932 0.068 0.000
I20.0 Unstable angina
0.931 0.069 0.000
I60 Subarachnoid haemorrhage
0.927 0.073 0.000
M65-M68 Disorders of synovium and tendon
0.925 0.075 0.000
M07 Psoriatic and enteropathic arthropathies
0.921 0.079 0.000
I69 Sequelae of cerebrovascular disease
0.920 0.080 0.000
M35 Other systemic involvement of connective tissue
0.917 0.083 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.916 0.084 0.000
M43 Other deforming dorsopathies
0.913 0.087 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.908 0.092 0.000
I63 Cerebral infarction
0.903 0.097 0.000
I34.1 Mitral (valve) prolapse
0.900 0.100 0.000
M43.1 Spondylolisthesis
0.899 0.101 0.000
M30 Polyarteritis nodosa and related conditions
0.894 0.106 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.891 0.109 0.000
M77 Other enthesopathies
0.889 0.111 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.889 0.111 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.886 0.114 0.000
I42.0 Dilated cardiomyopathy
0.882 0.118 0.000
M24.02 Loose body in joint (Upper arm)
0.882 0.118 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.879 0.121 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.878 0.122 0.000
I42.2 Other hypertrophic cardiomyopathy
0.871 0.129 0.000
M20 Acquired deformities of fingers and toes
0.869 0.131 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.868 0.132 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.866 0.134 0.000
M07.3 Other psoriatic arthropathies
0.866 0.134 0.000
M12 Other specific arthropathies
0.864 0.136 0.000
M76 Enthesopathies of lower limb, excluding foot
0.864 0.136 0.000
M65 Synovitis and tenosynovitis
0.861 0.139 0.000
M34 Systemic sclerosis
0.859 0.141 0.000
I25.4 Coronary artery aneurysm
0.858 0.142 0.000
I51 Complications and ill-defined descriptions of heart disease
0.857 0.143 0.000
M20.0 Deformity of finger(s)
0.854 0.146 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.852 0.148 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.852 0.148 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.851 0.149 0.000
M20.5 Other deformities of toe(s) (acquired)
0.849 0.151 0.000
M24.9 Joint derangement, unspecified
0.844 0.156 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.843 0.157 0.000
I44.0 Atrioventricular block, first degree
0.837 0.163 0.000
I65.2 Occlusion and stenosis of carotid artery
0.835 0.165 0.000
I24 Other acute ischaemic heart diseases
0.834 0.166 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.831 0.169 0.000
M84.4 Pathological fracture, not elsewhere classified
0.830 0.169 0.000
M24.56 Contracture of joint (Lower leg)
0.826 0.174 0.000
M85 Other disorders of bone density and structure
0.825 0.175 0.000
M71 Other bursopathies
0.824 0.176 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.824 0.176 0.000
I22 Subsequent myocardial infarction
0.819 0.181 0.000
I20.1 Angina pectoris with documented spasm
0.817 0.183 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.816 0.184 0.000
I25.3 Aneurysm of heart
0.815 0.185 0.000
I42.8 Other cardiomyopathies
0.814 0.186 0.000
I23 Certain current complications following acute myocardial infarction
0.814 0.186 0.000
I30 Acute pericarditis
0.812 0.188 0.000
M24.2 Disorder of ligament
0.810 0.190 0.000
M77.4 Metatarsalgia
0.808 0.192 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.807 0.193 0.000
I51.4 Myocarditis, unspecified
0.807 0.193 0.000
I51.6 Cardiovascular disease, unspecified
0.806 0.194 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.804 0.196 0.000
M65.3 Trigger finger
0.803 0.197 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.802 0.198 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.796 0.204 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.796 0.204 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.794 0.206 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.793 0.207 0.000
I20.9 Angina pectoris, unspecified
0.791 0.209 0.000
I42.9 Cardiomyopathy, unspecified
0.791 0.209 0.000
I44.6 Other and unspecified fascicular block
0.790 0.210 0.000
I05-I09 Chronic rheumatic heart diseases
0.787 0.213 0.000
M65.8 Other synovitis and tenosynovitis
0.785 0.215 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.778 0.222 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.776 0.224 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.775 0.225 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.774 0.226 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.773 0.227 0.000
I44.4 Left anterior fascicular block
0.770 0.229 0.000
M35.3 Polymyalgia rheumatica
0.771 0.229 0.000
M83 Adult osteomalacia
0.769 0.231 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.768 0.232 0.000
M82 Osteoporosis in diseases classified elsewhere
0.767 0.233 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.765 0.235 0.000
M23 Internal derangement of knee
0.765 0.235 0.000
M35.1 Other overlap syndromes
0.764 0.235 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
I47.0 Reentry ventricular arrhythmia
0.762 0.238 0.000
M24.07 Loose body in joint (Ankle and foot)
0.762 0.238 0.000
M65.34 Trigger finger-Hand
0.762 0.238 0.000
M24.03 Loose body in joint (Forearm)
0.758 0.242 0.000
M35.0 Sicca syndrome [Sjogren]
0.757 0.243 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.757 0.243 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.755 0.245 0.000
I05 Rheumatic mitral valve diseases
0.754 0.246 0.000
M24.51 Contracture of joint (Shoulder region)
0.753 0.247 0.000
M66 Spontaneous rupture of synovium and tendon
0.752 0.248 0.000
M11 Other crystal arthropathies
0.751 0.249 0.000
M12.3 Palindromic rheumatism
0.750 0.250 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.750 0.250 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.748 0.252 0.000
M30.0 Polyarteritis nodosa
0.746 0.254 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.746 0.254 0.000
M24.7 Protrusio acetabuli
0.745 0.255 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.745 0.255 0.000
M05 Seropositive rheumatoid arthritis
0.742 0.258 0.000
M24.54 Contracture of joint (Hand)
0.742 0.258 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.741 0.259 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.739 0.261 0.000
M34.9 Systemic sclerosis, unspecified
0.736 0.264 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.732 0.267 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.728 0.272 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.727 0.273 0.000
M35.8 Other specified systemic involvement of connective tissue
0.726 0.274 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.725 0.275 0.000
M77.0 Medial epicondylitis
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
M10.90 Gout, unspecified (Multiple sites)
0.722 0.278 0.000
M24.04 Loose body in joint (Hand)
0.721 0.279 0.000
M84.3 Stress fracture, not elsewhere classified
0.719 0.281 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M76.5 Patellar tendinitis
0.714 0.286 0.000
M50-M54 Other dorsopathies
0.714 0.286 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
I44.5 Left posterior fascicular block
0.713 0.287 0.000
M10.1 Lead-induced gout
0.713 0.287 0.000
M10.2 Drug-induced gout
0.713 0.287 0.000
M10.3 Gout due to impairment of renal function
0.713 0.287 0.000
M10.4 Other secondary gout
0.713 0.287 0.000
M23.8 Other internal derangements of knee
0.712 0.288 0.000
M10.91 Gout, unspecified (Shoulder region)
0.711 0.289 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.711 0.289 0.000
M10.98 Gout, unspecified (Other)
0.711 0.289 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.711 0.289 0.000
M24.6 Ankylosis of joint
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.709 0.291 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.707 0.293 0.000
M10.0 Idiopathic gout
0.706 0.294 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.705 0.295 0.000
I42.4 Endocardial fibroelastosis
0.705 0.295 0.000
I42.5 Other restrictive cardiomyopathy
0.705 0.295 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.705 0.295 0.000
M71.3 Other bursal cyst
0.701 0.298 0.000
M23.4 Loose body in knee
0.700 0.300 0.000
M84.2 Delayed union of fracture
0.699 0.301 0.000
M84.8 Other disorders of continuity of bone
0.699 0.301 0.000
M84.9 Disorder of continuity of bone, unspecified
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
M76.0 Gluteal tendinitis
0.697 0.303 0.000
M40 Kyphosis and lordosis
0.695 0.305 0.000
M86-M90 Other osteopathies
0.694 0.306 0.000
M10.92 Gout, unspecified (Upper arm)
0.693 0.306 0.000
M24.26 Disorder of ligament (Lower leg)
0.693 0.307 0.000
M72 Fibroblastic disorders
0.692 0.308 0.000
M76.6 Achilles tendinitis
0.692 0.308 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.691 0.309 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.690 0.309 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.690 0.309 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.690 0.309 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.690 0.309 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.690 0.309 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.690 0.309 0.000
M23.5 Chronic instability of knee
0.689 0.311 0.000
M54 Dorsalgia
0.689 0.311 0.000
I05.1 Rheumatic mitral insufficiency
0.689 0.311 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.688 0.311 0.000
M81 Osteoporosis without pathological fracture
0.688 0.312 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.685 0.315 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.685 0.315 0.000
M24.00 Loose body in joint (Multiple sites)
0.684 0.316 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.684 0.316 0.000
M24.06 Loose body in joint-Lower leg
0.684 0.316 0.000
M24.08 Loose body in joint (Other)
0.684 0.316 0.000
M24.09 Loose body in joint (Site unspecified)
0.684 0.316 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.683 0.317 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.683 0.317 0.000
I60.8 Other subarachnoid haemorrhage
0.682 0.318 0.000
I50.9 Heart failure, unspecified
0.681 0.319 0.000
I23.8 Other current complications following acute myocardial infarction
0.681 0.319 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.678 0.322 0.000
M42 Spinal osteochondrosis
0.676 0.324 0.000
M24.01 Loose body in joint (Shoulder region)
0.674 0.326 0.000
I44.1 Atrioventricular block, second degree
0.674 0.326 0.000
M10.93 Gout, unspecified (Forearm)
0.673 0.327 0.000
M65.1 Other infective (teno)synovitis
0.673 0.327 0.000
M85.6 Other cyst of bone
0.673 0.327 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.672 0.328 0.000
I05.9 Mitral valve disease, unspecified
0.672 0.328 0.000
M24.50 Contracture of joint (Multiple sites)
0.668 0.331 0.000
M24.52 Contracture of joint (Upper arm)
0.668 0.331 0.000
M24.53 Contracture of joint (Forearm)
0.668 0.331 0.000
M24.57 Contracture of joint (Ankle and foot)
0.668 0.331 0.000
M24.58 Contracture of joint (Other)
0.668 0.331 0.000
M24.59 Contracture of joint (Site unspecified)
0.668 0.331 0.000
M34.1 CR(E)ST syndrome
0.667 0.333 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.664 0.335 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.663 0.336 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.663 0.337 0.000
M24.28 Disorder of ligament (Other)
0.662 0.338 0.000
M77.5 Other enthesopathy of foot
0.662 0.338 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.662 0.338 0.000
M45-M49 Spondylopathies
0.661 0.339 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.660 0.340 0.000
M07.1 Arthritis mutilans
0.660 0.340 0.000
M07.2 Psoriatic spondylitis
0.660 0.340 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.660 0.340 0.000
M07.5 Arthropathy in ulcerative colitis
0.660 0.340 0.000
M07.6 Other enteropathic arthropathies
0.660 0.340 0.000
M77.1 Lateral epicondylitis
0.659 0.341 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.658 0.342 0.000
M35.2 Behcet's disease
0.657 0.343 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.657 0.343 0.000
M35.5 Multifocal fibrosclerosis
0.657 0.343 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.657 0.343 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.657 0.343 0.000
M43.6 Torticollis
0.657 0.343 0.000
M85.4 Solitary bone cyst
0.657 0.343 0.000
M12.2 Villonodular synovitis (pigmented)
0.656 0.344 0.000
M10.94 Gout, unspecified (Hand)
0.655 0.345 0.000
M43.2 Other fusion of spine
0.654 0.345 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.654 0.345 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.654 0.345 0.000
M43.5 Other recurrent vertebral subluxation
0.654 0.345 0.000
M43.8 Other specified deforming dorsopathies
0.654 0.345 0.000
M43.9 Deforming dorsopathy, unspecified
0.654 0.345 0.000
I65.1 Occlusion and stenosis of basilar artery
0.651 0.349 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.651 0.349 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.651 0.349 0.000
M54.2 Cervicalgia
0.650 0.350 0.000
M10.96 Gout, unspecified (Lower leg)
0.648 0.351 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.647 0.353 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.647 0.353 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.647 0.353 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.646 0.354 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.645 0.355 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.645 0.355 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.645 0.355 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.645 0.355 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.645 0.355 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.645 0.355 0.000
I20.8 Other forms of angina pectoris
0.642 0.358 0.000
I30.9 Acute pericarditis, unspecified
0.641 0.359 0.000
M30.2 Juvenile polyarteritis
0.641 0.359 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.641 0.359 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.641 0.359 0.000
M70.5 Other bursitis of knee
0.640 0.360 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.639 0.361 0.000
I05.0 Mitral stenosis
0.638 0.362 0.000
M77.2 Periarthritis of wrist
0.638 0.362 0.000
M77.3 Calcaneal spur
0.638 0.362 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.638 0.362 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.636 0.364 0.000
M54.22 Cervicalgia (Cervical region)
0.634 0.366 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.632 0.367 0.000
M54.8 Other dorsalgia
0.632 0.368 0.000
I30.1 Infective pericarditis
0.629 0.371 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.629 0.371 0.000
M70.2 Olecranon bursitis
0.627 0.373 0.000
I15 Secondary hypertension
0.627 0.373 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.627 0.373 0.000
M85.9 Disorder of bone density and structure, unspecified
0.626 0.374 0.000
M66.2 Spontaneous rupture of extensor tendons
0.625 0.375 0.000
M84.0 Malunion of fracture
0.625 0.375 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.625 0.375 0.000
I24.1 Dressler's syndrome
0.622 0.378 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.621 0.379 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.621 0.379 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.621 0.379 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.621 0.379 0.000
M07.38 Other psoriatic arthropathies (Other)
0.621 0.379 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.619 0.381 0.000
M12.1 Kaschin-Beck disease
0.619 0.381 0.000
M12.4 Intermittent hydrarthrosis
0.619 0.381 0.000
M12.5 Traumatic arthropathy
0.619 0.381 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.619 0.381 0.000
M76.1 Psoas tendinitis
0.619 0.381 0.000
M76.2 Iliac crest spur
0.619 0.381 0.000
M76.3 Iliotibial band syndrome
0.619 0.381 0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]
0.619 0.381 0.000
M76.7 Peroneal tendinitis
0.619 0.381 0.000
M76.9 Enthesopathy of lower limb, unspecified
0.619 0.381 0.000
M77.9 Enthesopathy, unspecified
0.619 0.381 0.000
M14 Arthropathies in other diseases classified elsewhere
0.618 0.381 0.000
I36 Nonrheumatic tricuspid valve disorders
0.618 0.382 0.000
M65.0 Abscess of tendon sheath
0.617 0.383 0.000
M65.2 Calcific tendinitis
0.617 0.383 0.000
M23.49 Loose body in knee-Unspec lig/men
0.617 0.383 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.616 0.384 0.000
M34.0 Progressive systemic sclerosis
0.616 0.384 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.616 0.384 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.614 0.386 0.000
I51.5 Myocardial degeneration
0.614 0.386 0.000
M71.38 Other bursal cyst (Other)
0.614 0.386 0.000
M83.8 Other adult osteomalacia
0.613 0.387 0.000
I63.8 Other cerebral infarction
0.613 0.387 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.611 0.389 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.611 0.389 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.611 0.389 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.611 0.389 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.611 0.389 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.611 0.389 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.611 0.389 0.000
M71.1 Other infective bursitis
0.610 0.389 0.000
M82.1 Osteoporosis in endocrine disorders
0.609 0.391 0.000
I37 Pulmonary valve disorders
0.609 0.391 0.000
I42.6 Alcoholic cardiomyopathy
0.609 0.391 0.000
M62 Other disorders of muscle
0.609 0.391 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.607 0.393 0.000
M76.56 Patellar tendinitis-Lower Leg
0.607 0.393 0.000
M34.8 Other forms of systemic sclerosis
0.606 0.394 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.605 0.395 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.605 0.395 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.605 0.395 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.605 0.395 0.000
M24.94 Joint derangement, unspecified (Hand)
0.605 0.395 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.605 0.395 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.605 0.395 0.000
M24.98 Joint derangement, unspecified (Other)
0.605 0.395 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.605 0.395 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.604 0.396 0.000
M77.02 Medial epicondylitis (Upper arm)
0.603 0.397 0.000
I33 Acute and subacute endocarditis
0.601 0.398 0.000
M99 Biomechanical lesions, not elsewhere classified
0.602 0.398 0.000
M67 Other disorders of synovium and tendon
0.599 0.401 0.000
M43.12 Spondylolisthesis (Cervical region)
0.598 0.401 0.000
M72.2 Plantar fascial fibromatosis
0.598 0.402 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.598 0.402 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.596 0.404 0.000
M81.4 Drug-induced osteoporosis
0.596 0.404 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.595 0.404 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.595 0.404 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.595 0.404 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.595 0.404 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.595 0.404 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.595 0.404 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.595 0.404 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.595 0.404 0.000
M75 Shoulder lesions
0.594 0.406 0.000
M06 Other rheumatoid arthritis
0.594 0.406 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.593 0.407 0.000
M13 Other arthritis
0.593 0.407 0.000
M70.7 Other bursitis of hip
0.592 0.408 0.000
M85.1 Skeletal fluorosis
0.592 0.408 0.000
M85.2 Hyperostosis of skull
0.592 0.408 0.000
M85.3 Osteitis condensans
0.592 0.408 0.000
M85.5 Aneurysmal bone cyst
0.592 0.408 0.000
M71.0 Abscess of bursa
0.591 0.409 0.000
M71.4 Calcium deposit in bursa
0.591 0.409 0.000
M71.5 Other bursitis, not elsewhere classified
0.591 0.409 0.000
M71.8 Other specified bursopathies
0.591 0.409 0.000
M71.9 Bursopathy, unspecified
0.591 0.409 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.586 0.414 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.584 0.416 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.584 0.416 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.584 0.416 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.584 0.416 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.584 0.416 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.584 0.416 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.584 0.416 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.584 0.416 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.583 0.417 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.582 0.418 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.582 0.418 0.000
I30.8 Other forms of acute pericarditis
0.582 0.418 0.000
M85.8 Other specified disorders of bone density and structure
0.581 0.419 0.000
M24.20 Disorder of ligament (Multiple sites)
0.580 0.419 0.000
M24.22 Disorder of ligament (Upper arm)
0.580 0.419 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.580 0.419 0.000
M24.29 Disorder of ligament (Site unspecified)
0.580 0.419 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.581 0.419 0.000
M77.40 Metatarsalgia-Mult sites
0.580 0.420 0.000
M77.41 Metatarsalgia-Shldr region
0.580 0.420 0.000
M77.42 Metatarsalgia-Upper arm
0.580 0.420 0.000
M77.43 Metatarsalgia-Forearm
0.580 0.420 0.000
M77.44 Metatarsalgia-Hand
0.580 0.420 0.000
M77.45 Metatarsalgia-Pelvic/Thigh
0.580 0.420 0.000
M77.46 Metatarsalgia-Lower Leg
0.580 0.420 0.000
M77.48 Metatarsalgia-Other
0.580 0.420 0.000
M77.49 Metatarsalgia-Site unspec
0.580 0.420 0.000
M24.1 Other articular cartilage disorders
0.578 0.422 0.000
M76.05 Gluteal tendinitis (Pelvic region and thigh)
0.578 0.422 0.000
M54.3 Sciatica
0.578 0.422 0.000
M54.4 Lumbago with sciatica
0.577 0.423 0.000
M23.43 Loose body in knee-Med lig/oth men
0.577 0.423 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.576 0.424 0.000
M65.30 Trigger finger-Mult sites
0.576 0.424 0.000
M65.31 Trigger finger-Shldr region
0.576 0.424 0.000
M65.32 Trigger finger-Upper arm
0.576 0.424 0.000
M65.33 Trigger finger-Forearm
0.576 0.424 0.000
M65.35 Trigger finger-Pelvic/thigh
0.576 0.424 0.000
M65.36 Trigger finger-Lower leg
0.576 0.424 0.000
M65.37 Trigger finger-Ankle/foot
0.576 0.424 0.000
M65.38 Trigger finger-Other
0.576 0.424 0.000
M65.39 Trigger finger-Site unspec
0.576 0.424 0.000
M76.66 Achilles tendinitis (Lower leg)
0.573 0.427 0.000
M24.23 Disorder of ligament (Forearm)
0.573 0.427 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.567 0.433 0.000
M54.9 Dorsalgia, unspecified
0.565 0.435 0.000
I06 Rheumatic aortic valve diseases
0.564 0.436 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.563 0.437 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.563 0.437 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.563 0.437 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.563 0.437 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.563 0.437 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.563 0.437 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.563 0.437 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.563 0.437 0.000
M46 Other inflammatory spondylopathies
0.563 0.437 0.000
M41 Scoliosis
0.562 0.438 0.000
M20.3 Other deformity of hallux (acquired)
0.561 0.439 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.561 0.439 0.000
I51.0 Cardiac septal defect, acquired
0.560 0.440 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.559 0.441 0.000
M11.9 Crystal arthropathy, unspecified
0.558 0.442 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.557 0.443 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.557 0.443 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.557 0.443 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.557 0.443 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.557 0.443 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.557 0.443 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.557 0.443 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.557 0.443 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.557 0.443 0.000
M11.2 Other chondrocalcinosis
0.557 0.443 0.000
M24.21 Disorder of ligament (Shoulder region)
0.555 0.445 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.555 0.445 0.000
M70.1 Bursitis of hand
0.555 0.445 0.000
M70.3 Other bursitis of elbow
0.555 0.445 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.555 0.445 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.555 0.445 0.000
M75.3 Calcific tendinitis of shoulder
0.553 0.447 0.000
M66.3 Spontaneous rupture of flexor tendons
0.552 0.448 0.000
M83.0 Puerperal osteomalacia
0.551 0.449 0.000
M83.1 Senile osteomalacia
0.551 0.449 0.000
M83.2 Adult osteomalacia due to malabsorption
0.551 0.449 0.000
M83.3 Adult osteomalacia due to malnutrition
0.551 0.449 0.000
M83.4 Aluminum bone disease
0.551 0.449 0.000
M83.5 Other drug-induced osteomalacia in adults
0.551 0.449 0.000
M83.9 Adult osteomalacia, unspecified
0.551 0.449 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.551 0.449 0.000
M85.0 Fibrous dysplasia (monostotic)
0.551 0.449 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.550 0.450 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.550 0.450 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.550 0.450 0.000
M61 Calcification and ossification of muscle
0.547 0.453 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.547 0.453 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.547 0.453 0.000
I44.3 Other and unspecified atrioventricular block
0.547 0.453 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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