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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17615906
log Bayes Factor = 13.0692
Chromosome 5   position 128,018,413  (GRCh37) Explore rs17615906 on Ensembl!
Variant rs17615906 is part of Cluster X0294

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I50 Heart failure
0.999 0.001 0.000
I34 Nonrheumatic mitral valve disorders
0.996 0.004 0.000
I47 Paroxysmal tachycardia
0.995 0.005 0.000
I47.1 Supraventricular tachycardia
0.993 0.007 0.000
I50.0 Congestive heart failure
0.991 0.009 0.000
I20-I25 Ischaemic heart diseases
0.990 0.010 0.000
I60-I69 Cerebrovascular diseases
0.986 0.014 0.000
I25 Chronic ischaemic heart disease
0.984 0.016 0.000
I25.1 Atherosclerotic heart disease
0.980 0.020 0.000
I42 Cardiomyopathy
0.972 0.028 0.000
M24 Other specific joint derangements
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.965 0.035 0.000
M20-M25 Other joint disorders
0.964 0.036 0.000
I34.0 Mitral (valve) insufficiency
0.961 0.039 0.000
I34.1 Mitral (valve) prolapse
0.960 0.040 0.000
I69 Sequelae of cerebrovascular disease
0.959 0.041 0.000
M80-M85 Disorders of bone density and structure
0.958 0.042 0.000
M84 Disorders of continuity of bone
0.955 0.045 0.000
M05-M14 Inflammatory polyarthropathies
0.953 0.047 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.952 0.048 0.000
M24.0 Loose body in joint
0.946 0.054 0.000
I50.1 Left ventricular failure
0.935 0.065 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.926 0.074 0.000
M10 Gout
0.921 0.079 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.919 0.081 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.919 0.081 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.914 0.086 0.000
I50.9 Heart failure, unspecified
0.913 0.087 0.000
M24.5 Contracture of joint
0.908 0.092 0.000
M10.9 Gout, unspecified
0.899 0.101 0.000
M65-M68 Disorders of synovium and tendon
0.889 0.111 0.000
M10.99 Gout, unspecified (Site unspecified)
0.888 0.112 0.000
I60 Subarachnoid haemorrhage
0.886 0.114 0.000
M24.02 Loose body in joint (Upper arm)
0.884 0.116 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.881 0.119 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.880 0.120 0.000
M35 Other systemic involvement of connective tissue
0.875 0.125 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.866 0.134 0.000
I65.2 Occlusion and stenosis of carotid artery
0.864 0.136 0.000
I42.9 Cardiomyopathy, unspecified
0.856 0.144 0.000
M65 Synovitis and tenosynovitis
0.856 0.144 0.000
I25.5 Ischaemic cardiomyopathy
0.840 0.160 0.000
M24.07 Loose body in joint (Ankle and foot)
0.837 0.163 0.000
I24 Other acute ischaemic heart diseases
0.837 0.163 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.826 0.174 0.000
M16.9 Coxarthrosis, unspecified
0.826 0.174 0.000
M15-M19 Arthrosis
0.826 0.174 0.000
M12 Other specific arthropathies
0.825 0.175 0.000
M24.2 Disorder of ligament
0.822 0.178 0.000
M06 Other rheumatoid arthritis
0.821 0.179 0.000
I30 Acute pericarditis
0.819 0.181 0.000
M16 Coxarthrosis [arthrosis of hip]
0.818 0.182 0.000
M24.9 Joint derangement, unspecified
0.817 0.182 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.817 0.183 0.000
I51 Complications and ill-defined descriptions of heart disease
0.816 0.184 0.000
I22 Subsequent myocardial infarction
0.815 0.185 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.812 0.188 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.811 0.189 0.000
I11 Hypertensive heart disease
0.808 0.192 0.000
I23 Certain current complications following acute myocardial infarction
0.806 0.194 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.805 0.194 0.000
M24.56 Contracture of joint (Lower leg)
0.804 0.196 0.000
M30 Polyarteritis nodosa and related conditions
0.803 0.197 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.799 0.201 0.000
I47.0 Reentry ventricular arrhythmia
0.799 0.201 0.000
M07 Psoriatic and enteropathic arthropathies
0.797 0.203 0.000
M60-M63 Disorders of muscles
0.797 0.203 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.792 0.208 0.000
M65.3 Trigger finger
0.791 0.209 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.790 0.210 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.789 0.211 0.000
M34 Systemic sclerosis
0.788 0.212 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.787 0.213 0.000
I42.2 Other hypertrophic cardiomyopathy
0.787 0.213 0.000
I42.8 Other cardiomyopathies
0.786 0.214 0.000
M84.4 Pathological fracture, not elsewhere classified
0.785 0.215 0.000
M85 Other disorders of bone density and structure
0.783 0.216 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.783 0.217 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.780 0.220 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.780 0.220 0.000
I51.6 Cardiovascular disease, unspecified
0.778 0.222 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.775 0.225 0.000
M45-M49 Spondylopathies
0.772 0.228 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.767 0.233 0.000
M06.9 Rheumatoid arthritis, unspecified
0.764 0.236 0.000
M65.8 Other synovitis and tenosynovitis
0.763 0.237 0.000
M35.1 Other overlap syndromes
0.757 0.242 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.752 0.247 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.752 0.248 0.000
M24.03 Loose body in joint (Forearm)
0.752 0.248 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.751 0.249 0.000
I25.3 Aneurysm of heart
0.750 0.250 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.750 0.250 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.747 0.253 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.745 0.255 0.000
M65.34 Trigger finger-Hand
0.745 0.255 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.743 0.257 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.742 0.258 0.000
I33 Acute and subacute endocarditis
0.738 0.262 0.000
I47.2 Ventricular tachycardia
0.738 0.262 0.000
M05 Seropositive rheumatoid arthritis
0.736 0.264 0.000
M24.54 Contracture of joint (Hand)
0.736 0.264 0.000
M40-M43 Deforming dorsopathies
0.735 0.265 0.000
I63 Cerebral infarction
0.734 0.266 0.000
M31 Other necrotising vasculopathies
0.733 0.266 0.000
M82 Osteoporosis in diseases classified elsewhere
0.733 0.267 0.000
M24.51 Contracture of joint (Shoulder region)
0.733 0.267 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.732 0.268 0.000
I25.4 Coronary artery aneurysm
0.724 0.276 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.722 0.278 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
M12.3 Palindromic rheumatism
0.717 0.283 0.000
M24.04 Loose body in joint (Hand)
0.715 0.284 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.714 0.286 0.000
I44 Atrioventricular and left bundle-branch block
0.712 0.288 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.712 0.288 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.710 0.290 0.000
M62 Other disorders of muscle
0.707 0.293 0.000
I51.4 Myocarditis, unspecified
0.706 0.294 0.000
I25.6 Silent myocardial ischaemia
0.705 0.294 0.000
M84.3 Stress fracture, not elsewhere classified
0.704 0.296 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.703 0.297 0.000
M35.3 Polymyalgia rheumatica
0.698 0.302 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.697 0.303 0.000
I42.5 Other restrictive cardiomyopathy
0.697 0.303 0.000
I42.4 Endocardial fibroelastosis
0.697 0.303 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.697 0.303 0.000
M35.0 Sicca syndrome [Sjogren]
0.695 0.305 0.000
M35.8 Other specified systemic involvement of connective tissue
0.694 0.306 0.000
M06.4 Inflammatory polyarthropathy
0.692 0.308 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.691 0.309 0.000
M24.6 Ankylosis of joint
0.688 0.312 0.000
M24.7 Protrusio acetabuli
0.687 0.313 0.000
M24.26 Disorder of ligament (Lower leg)
0.687 0.313 0.000
M83 Adult osteomalacia
0.687 0.313 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.686 0.314 0.000
M07.3 Other psoriatic arthropathies
0.685 0.315 0.000
M84.9 Disorder of continuity of bone, unspecified
0.684 0.315 0.000
M84.8 Other disorders of continuity of bone
0.684 0.315 0.000
M84.2 Delayed union of fracture
0.684 0.315 0.000
M32 Systemic lupus erythematosus
0.684 0.316 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.684 0.316 0.000
M08 Juvenile arthritis
0.684 0.316 0.000
M34.9 Systemic sclerosis, unspecified
0.683 0.317 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.683 0.317 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.683 0.317 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.679 0.321 0.000
M24.09 Loose body in joint (Site unspecified)
0.678 0.322 0.000
M24.08 Loose body in joint (Other)
0.678 0.322 0.000
M24.06 Loose body in joint-Lower leg
0.678 0.322 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.678 0.322 0.000
M24.00 Loose body in joint (Multiple sites)
0.678 0.322 0.000
I42.6 Alcoholic cardiomyopathy
0.675 0.325 0.000
I23.8 Other current complications following acute myocardial infarction
0.674 0.326 0.000
I49 Other cardiac arrhythmias
0.673 0.327 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.673 0.327 0.000
M00-M03 Infectious arthropathies
0.673 0.327 0.000
M24.28 Disorder of ligament (Other)
0.672 0.328 0.000
I42.0 Dilated cardiomyopathy
0.671 0.329 0.000
M30.0 Polyarteritis nodosa
0.670 0.330 0.000
M65.1 Other infective (teno)synovitis
0.669 0.331 0.000
M24.01 Loose body in joint (Shoulder region)
0.669 0.331 0.000
I30.9 Acute pericarditis, unspecified
0.668 0.332 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.666 0.334 0.000
M31.6 Other giant cell arteritis
0.665 0.335 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.664 0.336 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.664 0.336 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.664 0.336 0.000
I65.1 Occlusion and stenosis of basilar artery
0.664 0.336 0.000
I44.7 Left bundle-branch block, unspecified
0.662 0.338 0.000
M46 Other inflammatory spondylopathies
0.661 0.339 0.000
M10.4 Other secondary gout
0.661 0.339 0.000
M10.3 Gout due to impairment of renal function
0.661 0.339 0.000
M10.2 Drug-induced gout
0.661 0.339 0.000
M10.1 Lead-induced gout
0.661 0.339 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.660 0.340 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.659 0.341 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.659 0.341 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.659 0.341 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.659 0.341 0.000
M10.0 Idiopathic gout
0.654 0.346 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.652 0.348 0.000
I60.8 Other subarachnoid haemorrhage
0.652 0.348 0.000
M66 Spontaneous rupture of synovium and tendon
0.651 0.349 0.000
M16.3 Other dysplastic coxarthrosis
0.651 0.349 0.000
M24.59 Contracture of joint (Site unspecified)
0.651 0.349 0.000
M24.58 Contracture of joint (Other)
0.651 0.349 0.000
M24.57 Contracture of joint (Ankle and foot)
0.651 0.349 0.000
M24.53 Contracture of joint (Forearm)
0.651 0.349 0.000
M24.52 Contracture of joint (Upper arm)
0.651 0.349 0.000
M24.50 Contracture of joint (Multiple sites)
0.651 0.349 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.650 0.350 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.648 0.352 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.645 0.355 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.645 0.355 0.000
M10.98 Gout, unspecified (Other)
0.645 0.355 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.645 0.355 0.000
M10.91 Gout, unspecified (Shoulder region)
0.645 0.355 0.000
M33 Dermatopolymyositis
0.642 0.358 0.000
M22 Disorders of patella
0.640 0.360 0.000
I49.3 Ventricular premature depolarisation
0.639 0.361 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.637 0.363 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.636 0.364 0.000
M81 Osteoporosis without pathological fracture
0.635 0.365 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.635 0.365 0.000
M91-M94 Chondropathies
0.635 0.365 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.634 0.366 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.633 0.367 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.632 0.367 0.000
M85.6 Other cyst of bone
0.632 0.368 0.000
M86-M90 Other osteopathies
0.630 0.370 0.000
M10.92 Gout, unspecified (Upper arm)
0.628 0.371 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.628 0.372 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.627 0.372 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.627 0.372 0.000
M35.5 Multifocal fibrosclerosis
0.627 0.372 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.627 0.372 0.000
M35.2 Behcet's disease
0.627 0.372 0.000
M14 Arthropathies in other diseases classified elsewhere
0.627 0.373 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.626 0.374 0.000
M12.2 Villonodular synovitis (pigmented)
0.626 0.374 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.626 0.374 0.000
I24.1 Dressler's syndrome
0.624 0.376 0.000
M85.4 Solitary bone cyst
0.624 0.376 0.000
I30.1 Infective pericarditis
0.620 0.380 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.619 0.381 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.617 0.383 0.000
I36 Nonrheumatic tricuspid valve disorders
0.616 0.384 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.615 0.385 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.615 0.385 0.000
M65.2 Calcific tendinitis
0.614 0.386 0.000
M65.0 Abscess of tendon sheath
0.614 0.386 0.000
M43 Other deforming dorsopathies
0.612 0.387 0.000
M15 Polyarthrosis
0.611 0.389 0.000
I15 Secondary hypertension
0.611 0.389 0.000
M10.93 Gout, unspecified (Forearm)
0.610 0.390 0.000
I38 Endocarditis, valve unspecified
0.605 0.395 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.605 0.395 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.604 0.396 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.604 0.396 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.603 0.397 0.000
I62 Other nontraumatic intracranial haemorrhage
0.603 0.397 0.000
M11 Other crystal arthropathies
0.602 0.398 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.602 0.398 0.000
M62.8 Other specified disorders of muscle
0.602 0.398 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.597 0.403 0.000
M47 Spondylosis
0.597 0.403 0.000
M85.9 Disorder of bone density and structure, unspecified
0.594 0.405 0.000
M10.94 Gout, unspecified (Hand)
0.593 0.406 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.592 0.407 0.000
I49.5 Sick sinus syndrome
0.592 0.408 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.591 0.408 0.000
M12.5 Traumatic arthropathy
0.591 0.408 0.000
M12.4 Intermittent hydrarthrosis
0.591 0.408 0.000
M12.1 Kaschin-Beck disease
0.591 0.408 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.591 0.408 0.000
M24.29 Disorder of ligament (Site unspecified)
0.589 0.410 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.589 0.410 0.000
M24.22 Disorder of ligament (Upper arm)
0.589 0.410 0.000
M24.20 Disorder of ligament (Multiple sites)
0.589 0.410 0.000
M06.8 Other specified rheumatoid arthritis
0.589 0.411 0.000
M06.2 Rheumatoid bursitis
0.589 0.411 0.000
M06.1 Adult-onset Still's disease
0.589 0.411 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.588 0.412 0.000
I30.8 Other forms of acute pericarditis
0.587 0.413 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.587 0.413 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.587 0.413 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.587 0.413 0.000
M49 Spondylopathies in diseases classified elsewhere
0.586 0.413 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.586 0.414 0.000
M24.98 Joint derangement, unspecified (Other)
0.586 0.414 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.586 0.414 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.586 0.414 0.000
M24.94 Joint derangement, unspecified (Hand)
0.586 0.414 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.586 0.414 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.586 0.414 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.586 0.414 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.586 0.414 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.586 0.414 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.586 0.414 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.586 0.414 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.586 0.414 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.586 0.414 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.586 0.414 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.586 0.414 0.000
I51.5 Myocardial degeneration
0.585 0.415 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.585 0.415 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.581 0.419 0.000
I37 Pulmonary valve disorders
0.580 0.420 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.578 0.422 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.578 0.422 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.578 0.422 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.578 0.422 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.578 0.422 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.578 0.422 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.578 0.422 0.000
M47.8 Other spondylosis
0.576 0.424 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.576 0.424 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.576 0.424 0.000
M30.2 Juvenile polyarteritis
0.576 0.424 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.574 0.426 0.000
M82.1 Osteoporosis in endocrine disorders
0.572 0.428 0.000
M31.0 Hypersensitivity angiitis
0.572 0.428 0.000
M24.23 Disorder of ligament (Forearm)
0.572 0.428 0.000
M07.6 Other enteropathic arthropathies
0.571 0.429 0.000
M07.5 Arthropathy in ulcerative colitis
0.571 0.429 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.571 0.429 0.000
M07.2 Psoriatic spondylitis
0.571 0.429 0.000
M07.1 Arthritis mutilans
0.571 0.429 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.571 0.429 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.571 0.429 0.000
M61 Calcification and ossification of muscle
0.571 0.429 0.000
M31.1 Thrombotic microangiopathy
0.571 0.429 0.000
M43.1 Spondylolisthesis
0.569 0.431 0.000
I33.9 Acute endocarditis, unspecified
0.569 0.431 0.000
M84.0 Malunion of fracture
0.568 0.432 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.568 0.432 0.000
M65.39 Trigger finger-Site unspec
0.567 0.433 0.000
M65.38 Trigger finger-Other
0.567 0.433 0.000
M65.37 Trigger finger-Ankle/foot
0.567 0.433 0.000
M65.36 Trigger finger-Lower leg
0.567 0.433 0.000
M65.35 Trigger finger-Pelvic/thigh
0.567 0.433 0.000
M65.33 Trigger finger-Forearm
0.567 0.433 0.000
M65.32 Trigger finger-Upper arm
0.567 0.433 0.000
M65.31 Trigger finger-Shldr region
0.567 0.433 0.000
M65.30 Trigger finger-Mult sites
0.567 0.433 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.565 0.435 0.000
M34.0 Progressive systemic sclerosis
0.565 0.435 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.563 0.437 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.563 0.437 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.563 0.437 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.563 0.437 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.563 0.437 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.563 0.437 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.563 0.437 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.563 0.437 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.563 0.437 0.000
M85.5 Aneurysmal bone cyst
0.562 0.438 0.000
M85.3 Osteitis condensans
0.562 0.438 0.000
M85.2 Hyperostosis of skull
0.562 0.438 0.000
M85.1 Skeletal fluorosis
0.562 0.438 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.560 0.440 0.000
M85.0 Fibrous dysplasia (monostotic)
0.560 0.440 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.560 0.440 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.558 0.442 0.000
M10.96 Gout, unspecified (Lower leg)
0.558 0.442 0.000
M31.9 Necrotising vasculopathy, unspecified
0.557 0.442 0.000
M34.8 Other forms of systemic sclerosis
0.556 0.443 0.000
M48 Other spondylopathies
0.557 0.443 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.556 0.444 0.000
M62.0 Diastasis of muscle
0.556 0.444 0.000
I44.4 Left anterior fascicular block
0.552 0.448 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.551 0.449 0.000
I68.0 Cerebral amyloid angiopathy
0.549 0.451 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.547 0.453 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.547 0.453 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.547 0.453 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.547 0.453 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.547 0.453 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.547 0.453 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.544 0.456 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.544 0.456 0.000
I05-I09 Chronic rheumatic heart diseases
0.542 0.458 0.000
M47.82 Other spondylosis (Cervical region)
0.542 0.458 0.000
M10.90 Gout, unspecified (Multiple sites)
0.540 0.460 0.000
I35 Nonrheumatic aortic valve disorders
0.540 0.460 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.539 0.461 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.539 0.461 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.539 0.461 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.539 0.461 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.539 0.461 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.539 0.461 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.539 0.461 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.539 0.461 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.539 0.461 0.000
M62.6 Muscle strain
0.535 0.465 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.535 0.465 0.000
M16.5 Other posttraumatic coxarthrosis
0.534 0.466 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.532 0.468 0.000
M21 Other acquired deformities of limbs
0.532 0.468 0.000
M34.1 CR(E)ST syndrome
0.530 0.470 0.000
M13 Other arthritis
0.530 0.470 0.000
M05.8 Other seropositive rheumatoid arthritis
0.528 0.472 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.528 0.472 0.000
M05.2 Rheumatoid vasculitis
0.528 0.472 0.000
M05.1 Rheumatoid lung disease
0.528 0.472 0.000
M05.0 Felty's syndrome
0.528 0.472 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.528 0.472 0.000
M42 Spinal osteochondrosis
0.527 0.473 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.527 0.473 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.527 0.473 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.527 0.473 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.527 0.473 0.000
M31.8 Other specified necrotising vasculopathies
0.526 0.474 0.000
M31.7 Microscopic polyangiitis
0.526 0.474 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.526 0.474 0.000
M31.2 Lethal midline granuloma
0.526 0.474 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.526 0.474 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.526 0.474 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.526 0.474 0.000
M35.7 Hypermobility syndrome
0.525 0.475 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.525 0.475 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.525 0.475 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.525 0.475 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.525 0.475 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.525 0.475 0.000
M24.21 Disorder of ligament (Shoulder region)
0.524 0.476 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.523 0.477 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.522 0.478 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.521 0.479 0.000
I44.1 Atrioventricular block, second degree
0.521 0.479 0.000
M99 Biomechanical lesions, not elsewhere classified
0.520 0.480 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.519 0.481 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.518 0.482 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.517 0.482 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.517 0.482 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.517 0.482 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.517 0.482 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.517 0.482 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.517 0.482 0.000
M41 Scoliosis
0.515 0.485 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.514 0.486 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.514 0.486 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.514 0.486 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.514 0.486 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.514 0.486 0.000
I40.9 Acute myocarditis, unspecified
0.514 0.486 0.000
I40.8 Other acute myocarditis
0.514 0.486 0.000
I40.1 Isolated myocarditis
0.514 0.486 0.000
I40.0 Infective myocarditis
0.514 0.486 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.514 0.486 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.514 0.486 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.514 0.486 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.514 0.486 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.514 0.486 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.514 0.486 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.514 0.486 0.000
I48.4 Atypical atrial flutter
0.514 0.486 0.000
I48.3 Typical atrial flutter
0.514 0.486 0.000
I48.2 Chronic atrial fibrillation
0.514 0.486 0.000
I48.1 Persistent atrial fibrillation
0.514 0.486 0.000
I48.0 Paroxysmal atrial fibrillation
0.514 0.486 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.514 0.486 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.514 0.486 0.000
I02 Rheumatic chorea
0.514 0.486 0.000
I01 Rheumatic fever with heart involvement
0.514 0.486 0.000
I00 Rheumatic fever without mention of heart involvement
0.514 0.486 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.514 0.486 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.514 0.486 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.514 0.486 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.514 0.486 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.514 0.486 0.000
M12.38 Palindromic rheumatism (Other)
0.514 0.486 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.514 0.486 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.514 0.486 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.514 0.486 0.000
M12.34 Palindromic rheumatism (Hand)
0.514 0.486 0.000
M12.33 Palindromic rheumatism (Forearm)
0.514 0.486 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.514 0.486 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.514 0.486 0.000
M22.4 Chondromalacia patellae
0.514 0.486 0.000
I44.5 Left posterior fascicular block
0.510 0.489 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.510 0.490 0.000
M81.4 Drug-induced osteoporosis
0.510 0.490 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.509 0.491 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.508 0.491 0.000
I33.0 Acute and subacute infective endocarditis
0.507 0.493 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.507 0.493 0.000
M62.9 Disorder of muscle, unspecified
0.507 0.493 0.000
M62.4 Contracture of muscle
0.507 0.493 0.000
M62.3 Immobility syndrome (paraplegic)
0.507 0.493 0.000
M62.2 Ischaemic infarction of muscle
0.507 0.493 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.506 0.493 0.000
M66.2 Spontaneous rupture of extensor tendons
0.506 0.494 0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)
0.505 0.495 0.000
M84.38 Stress fracture, not elsewhere classified (Other)
0.505 0.495 0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)
0.505 0.495 0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)
0.505 0.495 0.000
M84.34 Stress fracture, not elsewhere classified (Hand)
0.505 0.495 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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