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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17429847
log Bayes Factor = 13.1629
Chromosome 4   position 16,735,814  (GRCh37) Explore rs17429847 on Ensembl!
Variant rs17429847 is part of Cluster X0273

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
E65-E68 Obesity and other hyperalimentation
0.996 0.004 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
E66 Obesity
0.993 0.007 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.992 0.008 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.991 0.009 0.000
Chapter XXI Factors influencing health status and contact with health services
0.990 0.010 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.985 0.015 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.984 0.016 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.983 0.017 0.000
Z90.7 Acquired absence of genital organ(s)
0.977 0.023 0.000
K50-K52 Noninfective enteritis and colitis
0.976 0.024 0.000
E66.8 Other obesity
0.972 0.028 0.000
Chapter II Neoplasms
0.972 0.028 0.000
K50 Crohn's disease [regional enteritis]
0.969 0.031 0.000
Z90.1 Acquired absence of breast(s)
0.969 0.031 0.000
E78.5 Hyperlipidaemia, unspecified
0.969 0.031 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.968 0.032 0.000
S80-S89 Injuries to the knee and lower leg
0.968 0.032 0.000
M75 Shoulder lesions
0.968 0.032 0.000
K04 Diseases of pulp and periapical tissues
0.966 0.034 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.964 0.036 0.000
E66.9 Obesity, unspecified
0.964 0.036 0.000
M05-M14 Inflammatory polyarthropathies
0.962 0.038 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
Chapter XIV Diseases of the genitourinary system
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.943 0.057 0.000
O60-O75 Complications of labour and delivery
0.943 0.057 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.942 0.058 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.937 0.063 0.000
K83 Other diseases of biliary tract
0.937 0.063 0.000
E00-E07 Disorders of thyroid gland
0.934 0.066 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.929 0.071 0.000
K02 Dental caries
0.929 0.071 0.000
Z93 Artificial opening status
0.928 0.072 0.000
K50.9 Crohn's disease, unspecified
0.926 0.074 0.000
C64-C68 Malignant neoplasms of urinary tract
0.924 0.076 0.000
K04.7 Periapical abscess without sinus
0.916 0.084 0.000
Z92 Personal history of medical treatment
0.914 0.086 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.913 0.087 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.912 0.088 0.000
N25-N29 Other disorders of kidney and ureter
0.911 0.089 0.000
M75.0 Adhesive capsulitis of shoulder
0.906 0.094 0.000
M80-M85 Disorders of bone density and structure
0.904 0.096 0.000
Chapter V Mental and behavioural disorders
0.903 0.097 0.000
S80 Superficial injury of lower leg
0.901 0.099 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.898 0.102 0.000
C67 Malignant neoplasm of bladder
0.895 0.105 0.000
Z90.2 Acquired absence of lung [part of]
0.893 0.107 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.893 0.107 0.000
E78.0 Pure hypercholesterolaemia
0.889 0.111 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.887 0.113 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.883 0.117 0.000
E50-E64 Other nutritional deficiencies
0.883 0.117 0.000
M13 Other arthritis
0.882 0.118 0.000
L40-L45 Papulosquamous disorders
0.882 0.118 0.000
Z80 Family history of malignant neoplasm
0.879 0.121 0.000
K65-K67 Diseases of peritoneum
0.878 0.122 0.000
N99-N99 Other disorders of the genitourinary system
0.877 0.123 0.000
M06 Other rheumatoid arthritis
0.876 0.124 0.000
S82 Fracture of lower leg, including ankle
0.876 0.124 0.000
E83 Disorders of mineral metabolism
0.875 0.125 0.000
O36 Maternal care for other known or suspected foetal problems
0.874 0.126 0.000
K02.9 Dental caries, unspecified
0.873 0.127 0.000
K83.1 Obstruction of bile duct
0.872 0.128 0.000
K11 Diseases of salivary glands
0.870 0.130 0.000
K50.1 Crohn's disease of large intestine
0.868 0.132 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.863 0.137 0.000
E04 Other non-toxic goitre
0.863 0.137 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.861 0.139 0.000
C50-C50 Malignant neoplasm of breast
0.860 0.140 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.858 0.142 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.856 0.144 0.000
L40 Psoriasis
0.854 0.146 0.000
K50.8 Other Crohn's disease
0.854 0.146 0.000
N28.1 Cyst of kidney, acquired
0.850 0.150 0.000
M75.5 Bursitis of shoulder
0.848 0.152 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.845 0.155 0.000
G40-G47 Episodic and paroxysmal disorders
0.841 0.159 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.841 0.159 0.000
O48 Prolonged pregnancy
0.839 0.161 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.838 0.162 0.000
E20-E35 Disorders of other endocrine glands
0.837 0.163 0.000
E53 Deficiency of other B group vitamins
0.837 0.163 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.836 0.164 0.000
M77 Other enthesopathies
0.836 0.164 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.836 0.164 0.000
E89.0 Postprocedural hypothyroidism
0.829 0.171 0.000
O46.9 Antepartum haemorrhage, unspecified
0.828 0.172 0.000
Z42 Follow-up care involving plastic surgery
0.828 0.172 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.828 0.172 0.000
Z41 Procedures for purposes other than remedying health state
0.828 0.172 0.000
K86 Other diseases of pancreas
0.826 0.174 0.000
Y57 Other and unspecified drugs and medicaments
0.824 0.176 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.820 0.179 0.000
O63 Long labour
0.820 0.180 0.000
M75.2 Bicipital tendinitis
0.820 0.180 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.820 0.180 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.819 0.181 0.000
Z93.3 Colostomy status
0.818 0.182 0.000
K35-K38 Diseases of appendix
0.818 0.182 0.000
E83.5 Disorders of calcium metabolism
0.817 0.183 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
Z53.0 Procedure not carried out because of contraindication
0.812 0.188 0.000
K09 Cysts of oral region, not elsewhere classified
0.809 0.191 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.809 0.191 0.000
G30-G32 Other degenerative diseases of the nervous system
0.809 0.191 0.000
M13.9 Arthritis, unspecified
0.807 0.193 0.000
Z93.2 Ileostomy status
0.806 0.194 0.000
S70-S79 Injuries to the hip and thigh
0.806 0.194 0.000
G47 Sleep disorders
0.805 0.195 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.804 0.195 0.000
E53.8 Deficiency of other specified B group vitamins
0.804 0.196 0.000
K04.8 Radicular cyst
0.804 0.196 0.000
M75.4 Impingement syndrome of shoulder
0.803 0.197 0.000
Z93.6 Other artificial openings of urinary tract status
0.802 0.198 0.000
M05 Seropositive rheumatoid arthritis
0.801 0.199 0.000
Y52 Agents primarily affecting the cardiovascular system
0.800 0.200 0.000
G20-G26 Extrapyramidal and movement disorders
0.797 0.203 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.796 0.204 0.000
L82 Seborrhoeic keratosis
0.795 0.205 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.794 0.206 0.000
C91 Lymphoid leukaemia
0.794 0.206 0.000
C67.1 Dome of bladder
0.792 0.208 0.000
Y43 Primarily systemic agents
0.791 0.209 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.790 0.210 0.000
E73 Lactose intolerance
0.787 0.213 0.000
O36.8 Maternal care for other specified foetal problems
0.787 0.213 0.000
C67.3 Anterior wall of bladder
0.786 0.214 0.000
M84 Disorders of continuity of bone
0.786 0.214 0.000
Z47 Other orthopaedic follow-up care
0.785 0.215 0.000
K04.5 Chronic apical periodontitis
0.784 0.216 0.000
K83.0 Cholangitis
0.782 0.218 0.000
C51-C58 Malignant neoplasms of female genital organs
0.781 0.219 0.000
C50 Malignant neoplasm of breast
0.781 0.219 0.000
M75.3 Calcific tendinitis of shoulder
0.780 0.220 0.000
S00-S09 Injuries to the head
0.780 0.220 0.000
E04.2 Non-toxic multinodular goitre
0.780 0.220 0.000
S82.2 Fracture of shaft of tibia
0.779 0.220 0.000
K66 Other disorders of peritoneum
0.779 0.220 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.779 0.221 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.778 0.222 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.777 0.223 0.000
K83.8 Other specified diseases of biliary tract
0.777 0.223 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.777 0.223 0.000
K00 Disorders of tooth development and eruption
0.777 0.223 0.000
O62 Abnormalities of forces of labour
0.776 0.224 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.775 0.225 0.000
D00-D09 In situ neoplasms
0.774 0.225 0.000
N17-N19 Renal failure
0.773 0.227 0.000
Z97 Presence of other devices
0.772 0.228 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.770 0.230 0.000
S80.0 Contusion of knee
0.768 0.232 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.766 0.234 0.000
K13 Other diseases of lip and oral mucosa
0.766 0.234 0.000
O66 Other obstructed labour
0.766 0.234 0.000
K05 Gingivitis and periodontal diseases
0.765 0.235 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.765 0.235 0.000
L40.9 Psoriasis, unspecified
0.764 0.236 0.000
M00-M03 Infectious arthropathies
0.764 0.236 0.000
Z90.3 Acquired absence of part of stomach
0.764 0.236 0.000
M71 Other bursopathies
0.762 0.238 0.000
M06.9 Rheumatoid arthritis, unspecified
0.762 0.238 0.000
K11.2 Sialoadenitis
0.761 0.238 0.000
E40-E46 Malnutrition
0.760 0.240 0.000
L40.5 Arthropathic psoriasis
0.758 0.242 0.000
C67.5 Bladder neck
0.758 0.242 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.755 0.245 0.000
O41 Other disorders of amniotic fluid and membranes
0.755 0.245 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.754 0.246 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.754 0.246 0.000
G70-G73 Diseases of myoneural junction and muscle
0.754 0.246 0.000
S82.8 Fractures of other parts of lower leg
0.752 0.248 0.000
Chapter XXII Codes for special purposes
0.751 0.249 0.000
S80.9 Superficial injury of lower leg, unspecified
0.751 0.249 0.000
W20-W49 Exposure to inanimate mechanical forces
0.750 0.250 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.750 0.250 0.000
K04.6 Periapical abscess with sinus
0.748 0.252 0.000
M81 Osteoporosis without pathological fracture
0.747 0.253 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.747 0.253 0.000
N28.8 Other specified disorders of kidney and ureter
0.746 0.253 0.000
K50.0 Crohn's disease of small intestine
0.745 0.255 0.000
O73 Retained placenta and membranes, without haemorrhage
0.745 0.255 0.000
S80.8 Other superficial injuries of lower leg
0.743 0.257 0.000
Y57.9 Drug or medicament, unspecified
0.743 0.257 0.000
K10 Other diseases of jaws
0.742 0.258 0.000
M06.0 Seronegative rheumatoid arthritis
0.742 0.258 0.000
X50-X57 Overexertion, travel and privation
0.742 0.258 0.000
C88 Malignant immunoproliferative diseases
0.742 0.258 0.000
S60-S69 Injuries to the wrist and hand
0.741 0.259 0.000
G47.3 Sleep apnoea
0.741 0.259 0.000
T92 Sequelae of injuries of upper limb
0.739 0.261 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.739 0.261 0.000
Z92.8 Personal history of other medical treatment
0.736 0.264 0.000
Y00-Y09 Assault
0.736 0.264 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.735 0.265 0.000
W50-W64 Exposure to animate mechanical forces
0.734 0.266 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.734 0.266 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.734 0.266 0.000
Z43 Attention to artificial openings
0.733 0.267 0.000
M65-M68 Disorders of synovium and tendon
0.732 0.268 0.000
M76 Enthesopathies of lower limb, excluding foot
0.732 0.268 0.000
C67.4 Posterior wall of bladder
0.732 0.268 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.730 0.269 0.000
O47 False labour
0.730 0.270 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.730 0.270 0.000
K85 Acute pancreatitis
0.728 0.272 0.000
V20-V29 Motorcycle rider injured in transport accident
0.728 0.272 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.727 0.273 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.726 0.274 0.000
C01 Malignant neoplasm of base of tongue
0.725 0.275 0.000
K82 Other diseases of gallbladder
0.724 0.276 0.000
C50.2 Upper-inner quadrant of breast
0.723 0.277 0.000
Z90.0 Acquired absence of part of head and neck
0.721 0.279 0.000
M91-M94 Chondropathies
0.721 0.279 0.000
L60-L75 Disorders of skin appendages
0.720 0.280 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.720 0.280 0.000
M13.94 Arthritis, unspecified (Hand)
0.720 0.280 0.000
Chapter VII Diseases of the eye and adnexa
0.719 0.281 0.000
F30-F39 Mood [affective] disorders
0.719 0.281 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
K02.8 Other dental caries
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
Z49 Care involving dialysis
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
E67 Other hyperalimentation
0.714 0.286 0.000
E68 Sequelae of hyperalimentation
0.714 0.286 0.000
E65 Localised adiposity
0.714 0.286 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.713 0.287 0.000
K66.0 Peritoneal adhesions
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.712 0.288 0.000
E66.1 Drug-induced obesity
0.712 0.288 0.000
E66.0 Obesity due to excess calories
0.712 0.288 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.712 0.288 0.000
K03 Other diseases of hard tissues of teeth
0.711 0.289 0.000
E04.9 Non-toxic goitre, unspecified
0.711 0.289 0.000
S82.20 Fracture of shaft of tibia (closed)
0.711 0.289 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.711 0.289 0.000
K36 Other appendicitis
0.710 0.290 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.709 0.291 0.000
Z48 Other surgical follow-up care
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.709 0.291 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.708 0.292 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.707 0.293 0.000
Z89 Acquired absence of limb
0.706 0.293 0.000
Z84 Family history of other conditions
0.706 0.293 0.000
Z81 Family history of mental and behavioural disorders
0.706 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
E78.8 Other disorders of lipoprotein metabolism
0.706 0.294 0.000
E78.6 Lipoprotein deficiency
0.706 0.294 0.000
E78.4 Other hyperlipidaemia
0.706 0.294 0.000
E78.3 Hyperchylomicronaemia
0.706 0.294 0.000
E78.2 Mixed hyperlipidaemia
0.706 0.294 0.000
E78.1 Pure hyperglyceridaemia
0.706 0.294 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.706 0.294 0.000
G47.9 Sleep disorder, unspecified
0.706 0.294 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.705 0.294 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
O45 Premature separation of placenta [abruptio placentae]
0.705 0.295 0.000
O44 Placenta praevia
0.705 0.295 0.000
O43 Placental disorders
0.705 0.295 0.000
O33 Maternal care for known or suspected disproportion
0.705 0.295 0.000
O31 Complications specific to multiple gestation
0.705 0.295 0.000
O40 Polyhydramnios
0.705 0.295 0.000
G30 Alzheimer's disease
0.703 0.297 0.000
N17 Acute renal failure
0.703 0.297 0.000
L40.8 Other psoriasis
0.703 0.297 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.702 0.297 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.702 0.298 0.000
N40-N51 Diseases of male genital organs
0.702 0.298 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.699 0.301 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.699 0.301 0.000
S42 Fracture of shoulder and upper arm
0.698 0.302 0.000
Y45.2 Propionic acid derivatives
0.697 0.303 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.697 0.303 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.697 0.303 0.000
N00-N08 Glomerular diseases
0.697 0.303 0.000
S81 Open wound of lower leg
0.696 0.304 0.000
K70-K77 Diseases of liver
0.695 0.305 0.000
S01 Open wound of head
0.695 0.305 0.000
M13.0 Polyarthritis, unspecified
0.694 0.305 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.694 0.306 0.000
S89 Other and unspecified injuries of lower leg
0.694 0.306 0.000
S88 Traumatic amputation of lower leg
0.694 0.306 0.000
S87 Crushing injury of lower leg
0.694 0.306 0.000
S86 Injury of muscle and tendon at lower leg level
0.694 0.306 0.000
S85 Injury of blood vessels at lower leg level
0.694 0.306 0.000
S84 Injury of nerves at lower leg level
0.694 0.306 0.000
M75.8 Other shoulder lesions
0.694 0.306 0.000
M75.9 Shoulder lesion, unspecified
0.694 0.306 0.000
O63.9 Long labour, unspecified
0.693 0.307 0.000
M40-M43 Deforming dorsopathies
0.692 0.307 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.692 0.308 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.692 0.308 0.000
K04.3 Abnormal hard tissue formation in pulp
0.692 0.308 0.000
K04.2 Pulp degeneration
0.692 0.308 0.000
K04.1 Necrosis of pulp
0.692 0.308 0.000
K04.0 Pulpitis
0.692 0.308 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.692 0.308 0.000
E06 Thyroiditis
0.692 0.308 0.000
M14 Arthropathies in other diseases classified elsewhere
0.690 0.310 0.000
M12 Other specific arthropathies
0.690 0.310 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.690 0.310 0.000
M08 Juvenile arthritis
0.690 0.310 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.690 0.310 0.000
G90-G99 Other disorders of the nervous system
0.689 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
K86.3 Pseudocyst of pancreas
0.689 0.311 0.000
C91.1 Chronic lymphocytic leukaemia
0.689 0.311 0.000
M86-M90 Other osteopathies
0.688 0.312 0.000
L50-L54 Urticaria and erythema
0.688 0.312 0.000
M07 Psoriatic and enteropathic arthropathies
0.687 0.313 0.000
O63.0 Prolonged first stage (of labour)
0.686 0.314 0.000
O36.9 Maternal care for foetal problem, unspecified
0.686 0.314 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.685 0.314 0.000
M20-M25 Other joint disorders
0.686 0.314 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.685 0.315 0.000
V10-V19 Pedal cyclist injured in transport accident
0.685 0.315 0.000
S12 Fracture of neck
0.683 0.317 0.000
S90-S99 Injuries to the ankle and foot
0.682 0.318 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.682 0.318 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.681 0.319 0.000
M77.0 Medial epicondylitis
0.681 0.319 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.679 0.321 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.678 0.322 0.000
S70 Superficial injury of hip and thigh
0.677 0.323 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.677 0.323 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.676 0.323 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.676 0.323 0.000
O74 Complications of anaesthesia during labour and delivery
0.676 0.324 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.676 0.324 0.000
O61 Failed induction of labour
0.676 0.324 0.000
O60 Preterm delivery
0.676 0.324 0.000
Y40 Systemic antibiotics
0.676 0.324 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.675 0.324 0.000
C95 Leukaemia of unspecified cell type
0.675 0.324 0.000
C94 Other leukaemias of specified cell type
0.675 0.324 0.000
C93 Monocytic leukaemia
0.675 0.324 0.000
C92 Myeloid leukaemia
0.675 0.324 0.000
C86 Other specified types of T/NK-cell lymphoma
0.675 0.324 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.675 0.324 0.000
S50-S59 Injuries to the elbow and forearm
0.675 0.325 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.674 0.326 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.674 0.326 0.000
O42 Premature rupture of membranes
0.673 0.327 0.000
E07 Other disorders of thyroid
0.673 0.327 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.673 0.327 0.000
E83.3 Disorders of phosphorus metabolism
0.672 0.327 0.000
M80 Osteoporosis with pathological fracture
0.672 0.328 0.000
Y59 Other and unspecified vaccines and biological substances
0.672 0.328 0.000
Y58 Bacterial vaccines
0.672 0.328 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.672 0.328 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.672 0.328 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.672 0.328 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.672 0.328 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
Y48 Anaesthetics and therapeutic gases
0.672 0.328 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.672 0.328 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.672 0.328 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
K83.9 Disease of biliary tract, unspecified
0.672 0.328 0.000
K83.5 Biliary cyst
0.672 0.328 0.000
K83.4 Spasm of sphincter of Oddi
0.672 0.328 0.000
K83.3 Fistula of bile duct
0.672 0.328 0.000
K83.2 Perforation of bile duct
0.672 0.328 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.671 0.329 0.000
M84.0 Malunion of fracture
0.671 0.329 0.000
C07 Malignant neoplasm of parotid gland
0.670 0.330 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.670 0.330 0.000
T79-T79 Certain early complications of trauma
0.670 0.330 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.670 0.330 0.000
E00 Congenital iodine-deficiency syndrome
0.670 0.330 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.670 0.330 0.000
K81 Cholecystitis
0.669 0.331 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.669 0.331 0.000
F10.3 Withdrawal state
0.669 0.331 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.668 0.332 0.000
K11.1 Hypertrophy of salivary gland
0.667 0.332 0.000
C67.2 Lateral wall of bladder
0.667 0.333 0.000
N99.5 Malfunction of external stoma of urinary tract
0.667 0.333 0.000
C81 Hodgkin's disease
0.667 0.333 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.667 0.333 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.667 0.333 0.000
T90 Sequelae of injuries of head
0.666 0.334 0.000
L10-L14 Bullous disorders
0.666 0.334 0.000
K02.5 Caries with pulp exposure
0.666 0.334 0.000
K02.4 Odontoclasia
0.666 0.334 0.000
K02.3 Arrested dental caries
0.666 0.334 0.000
K02.2 Caries of cementum
0.666 0.334 0.000
K02.1 Caries of dentin
0.666 0.334 0.000
K02.0 Caries limited to enamel
0.666 0.334 0.000
M77.4 Metatarsalgia
0.666 0.334 0.000
Z93.9 Artificial opening status, unspecified
0.665 0.334 0.000
Z93.8 Other artificial opening status
0.665 0.334 0.000
Z93.5 Cystostomy status
0.665 0.334 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.665 0.335 0.000
O32.0 Maternal care for unstable lie
0.664 0.336 0.000
M11 Other crystal arthropathies
0.663 0.337 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.663 0.337 0.000
W00-W19 Falls
0.663 0.337 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.662 0.337 0.000
C66 Malignant neoplasm of ureter
0.662 0.337 0.000
C65 Malignant neoplasm of renal pelvis
0.662 0.337 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.663 0.337 0.000
Q60-Q64 Congenital malformations of the urinary system
0.661 0.339 0.000
C09 Malignant neoplasm of tonsil
0.661 0.339 0.000
K51 Ulcerative colitis
0.660 0.340 0.000
Y43.3 Other antineoplastic drugs
0.660 0.340 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.660 0.340 0.000
K65 Peritonitis
0.659 0.341 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.659 0.341 0.000
Chapter VIII Diseases of the ear and mastoid process
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.659 0.341 0.000
E23 Hypofunction and other disorders of pituitary gland
0.659 0.341 0.000
K09.2 Other cysts of jaw
0.658 0.342 0.000
S71 Open wound of hip and thigh
0.657 0.342 0.000
O62.2 Other uterine inertia
0.656 0.344 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.655 0.344 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.655 0.345 0.000
Z92.9 Personal history of medical treatment, unspecified
0.655 0.345 0.000
Z92.5 Personal history of rehabilitation measures
0.655 0.345 0.000
Z44 Fitting and adjustment of external prosthetic device
0.654 0.345 0.000
S61 Open wound of wrist and hand
0.654 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.654 0.346 0.000
C67.6 Ureteric orifice
0.654 0.346 0.000
N26 Unspecified contracted kidney
0.653 0.347 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.653 0.347 0.000
N27 Small kidney of unknown cause
0.653 0.347 0.000
N25 Disorders resulting from impaired renal tubular function
0.653 0.347 0.000
N17.9 Acute renal failure, unspecified
0.652 0.348 0.000
D45 Polycythaemia vera
0.652 0.348 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.652 0.348 0.000
T14 Injury of unspecified body region
0.650 0.350 0.000
O32.1 Maternal care for breech presentation
0.650 0.350 0.000
K12 Stomatitis and related lesions
0.649 0.351 0.000
S82.5 Fracture of medial malleolus
0.649 0.351 0.000
N80 Endometriosis
0.649 0.351 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.648 0.352 0.000
M83 Adult osteomalacia
0.648 0.352 0.000
M82 Osteoporosis in diseases classified elsewhere
0.648 0.352 0.000
S42.0 Fracture of clavicle
0.648 0.352 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.648 0.352 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.647 0.352 0.000
F70-F79 Mental retardation
0.647 0.352 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.647 0.353 0.000
K11.8 Other diseases of salivary glands
0.647 0.353 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.646 0.354 0.000
S80.7 Multiple superficial injuries of lower leg
0.646 0.354 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.646 0.354 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.645 0.354 0.000
Q50-Q56 Congenital malformations of genital organs
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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