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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28511923
log Bayes Factor = 45.3247
Chromosome 6   position 33,023,880  (GRCh37) Explore Affx-28511923 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.1 With ketoacidosis
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.995 0.005 0.000
E16.2 Hypoglycaemia, unspecified
0.983 0.017 0.000
E14.3 With ophthalmic complications
0.981 0.019 0.000
E16 Other disorders of pancreatic internal secretion
0.973 0.027 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.966 0.034 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.962 0.038 0.000
E10.2 With renal complications
0.941 0.059 0.000
E10.4 With neurological complications
0.939 0.061 0.000
E10.5 With peripheral circulatory complications
0.912 0.088 0.000
E11 Non-insulin-dependent diabetes mellitus
0.887 0.113 0.000
E14.9 Without complications
0.886 0.114 0.000
E13 Other specified diabetes mellitus
0.877 0.123 0.000
E14.6 With other specified complications
0.864 0.136 0.000
E00-E07 Disorders of thyroid gland
0.861 0.139 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.861 0.139 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.854 0.146 0.000
E10.0 With coma
0.851 0.149 0.000
K90 Intestinal malabsorption
0.843 0.157 0.000
E05.9 Thyrotoxicosis, unspecified
0.833 0.167 0.000
E11.5 With peripheral circulatory complications
0.815 0.185 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.807 0.193 0.000
E13.9 Without complications
0.770 0.230 0.000
E40-E46 Malnutrition
0.762 0.238 0.000
E11.6 With other specified complications
0.754 0.246 0.000
E11.8 With unspecified complications
0.753 0.247 0.000
E10.8 With unspecified complications
0.734 0.266 0.000
E14.8 With unspecified complications
0.724 0.276 0.000
E11.1 With ketoacidosis
0.721 0.279 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E14.2 Withrenal complications
0.716 0.284 0.000
E14.7 With multiple complications
0.713 0.287 0.000
E14.0 With coma
0.713 0.287 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.711 0.289 0.000
E10.7 With multiple complications
0.709 0.291 0.000
K90.9 Intestinal malabsorption, unspecified
0.705 0.295 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.697 0.303 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.697 0.303 0.000
E16.4 Abnormal secretion of gastrin
0.697 0.303 0.000
E16.3 Increased secretion of glucagon
0.697 0.303 0.000
E11.0 With coma
0.694 0.306 0.000
E15 Nondiabetic hypoglycaemic coma
0.693 0.307 0.000
E10.6 With other specified complications
0.691 0.309 0.000
E14.5 With peripheral circulatory complications
0.688 0.312 0.000
E13.3 With ophthalmic complications
0.672 0.328 0.000
E11.7 With multiple complications
0.672 0.328 0.000
E14.1 With ketoacidosis
0.666 0.334 0.000
E14.4 With neurological complications
0.649 0.351 0.000
E16.1 Other hypoglycaemia
0.646 0.354 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.629 0.371 0.000
E13.8 With unspecified complications
0.629 0.371 0.000
E13.7 With multiple complications
0.629 0.371 0.000
E13.6 With other specified complications
0.629 0.371 0.000
E13.5 With peripheral circulatory complications
0.629 0.371 0.000
E13.4 With neurological complications
0.629 0.371 0.000
E13.2 With renal complications
0.629 0.371 0.000
E13.1 With ketoacidosis
0.629 0.371 0.000
E13.0 With coma
0.629 0.371 0.000
E46 Unspecified protein-energy malnutrition
0.618 0.382 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.617 0.383 0.000
E00 Congenital iodine-deficiency syndrome
0.617 0.383 0.000
E05.5 Thyroid crisis or storm
0.617 0.383 0.000
E05.4 Thyrotoxicosis factitia
0.617 0.383 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.617 0.383 0.000
E11.3 With ophthalmic complications
0.611 0.389 0.000
K90.3 Pancreatic steatorrhoea
0.604 0.396 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.604 0.396 0.000
K90.1 Tropical sprue
0.604 0.396 0.000
E05.8 Other thyrotoxicosis
0.589 0.411 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.546 0.454 0.000
E45 Retarded development following protein-energy malnutrition
0.546 0.454 0.000
E43 Unspecified severe protein-energy malnutrition
0.546 0.454 0.000
E42 Marasmic kwashiorkor
0.546 0.454 0.000
E41 Nutritional marasmus
0.546 0.454 0.000
E40 Kwashiorkor
0.546 0.454 0.000
E11.2 With renal complications
0.524 0.476 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.521 0.479 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E11.4 With neurological complications
0.471 0.529 0.000
K90.8 Other intestinal malabsorption
0.443 0.556 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.442 0.557 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.442 0.557 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.442 0.557 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.442 0.557 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.442 0.557 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.442 0.557 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.442 0.557 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.442 0.557 0.000
E07 Other disorders of thyroid
0.413 0.587 0.000
E44.1 Mild protein-energy malnutrition
0.392 0.608 0.000
E44.0 Moderate protein-energy malnutrition
0.392 0.608 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.365 0.635 0.000
E03 Other hypothyroidism
0.347 0.653 0.000
E06 Thyroiditis
0.346 0.654 0.000
E65-E68 Obesity and other hyperalimentation
0.304 0.696 0.000
E07.1 Dyshormogenetic goitre
0.296 0.704 0.000
E07.0 Hypersecretion of calcitonin
0.296 0.704 0.000
E03.8 Other specified hypothyroidism
0.286 0.714 0.000
E04 Other non-toxic goitre
0.281 0.719 0.000
E06.9 Thyroiditis, unspecified
0.264 0.736 0.000
E04.2 Non-toxic multinodular goitre
0.260 0.740 0.000
E03.5 Myxoedema coma
0.249 0.751 0.000
E03.4 Atrophy of thyroid (acquired)
0.249 0.751 0.000
E03.3 Postinfectious hypothyroidism
0.249 0.751 0.000
E06.4 Drug-induced thyroiditis
0.248 0.752 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.248 0.752 0.000
E06.0 Acute thyroiditis
0.248 0.752 0.000
E03.1 Congenital hypothyroidism without goitre
0.247 0.753 0.000
E50-E64 Other nutritional deficiencies
0.241 0.758 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.234 0.766 0.000
E07.9 Disorder of thyroid, unspecified
0.222 0.778 0.000
E67 Other hyperalimentation
0.218 0.782 0.000
E68 Sequelae of hyperalimentation
0.218 0.782 0.000
E07.8 Other specified disorders of thyroid
0.215 0.784 0.000
E06.5 Other chronic thyroiditis
0.215 0.785 0.000
E06.1 Subacute thyroiditis
0.213 0.787 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.203 0.797 0.000
E04.8 Other specified non-toxic goitre
0.202 0.798 0.000
E20-E35 Disorders of other endocrine glands
0.197 0.803 0.000
E54 Ascorbic acid deficiency
0.190 0.809 0.000
E26 Hyperaldosteronism
0.181 0.819 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.173 0.827 0.001
E63 Other nutritional deficiencies
0.173 0.827 0.001
E50 Vitamin A deficiency
0.173 0.827 0.001
E60 Dietary zinc deficiency
0.173 0.827 0.001
E59 Dietary selenium deficiency
0.173 0.827 0.001
E52 Niacin deficiency [pellagra]
0.173 0.827 0.001
E26.0 Primary hyperaldosteronism
0.165 0.835 0.000
E51 Thiamine deficiency
0.163 0.836 0.001
E24 Cushing's syndrome
0.163 0.837 0.000
E58 Dietary calcium deficiency
0.158 0.841 0.001
E67.8 Other specified hyperalimentation
0.156 0.843 0.000
E67.3 Hypervitaminosis D
0.156 0.843 0.000
E67.2 Megavitamin-B6 syndrome
0.156 0.843 0.000
E67.1 Hypercarotenaemia
0.156 0.843 0.000
E67.0 Hypervitaminosis A
0.156 0.843 0.000
E56 Other vitamin deficiencies
0.150 0.850 0.001
E25 Adrenogenital disorders
0.149 0.851 0.000
E26.9 Hyperaldosteronism, unspecified
0.143 0.857 0.000
E34 Other endocrine disorders
0.143 0.857 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.141 0.858 0.000
E32 Diseases of thymus
0.141 0.858 0.000
E30 Disorders of puberty, not elsewhere classified
0.141 0.858 0.000
E65 Localised adiposity
0.140 0.859 0.000
E29 Testicular dysfunction
0.140 0.860 0.000
E24.0 Pituitary-dependent Cushing's disease
0.139 0.861 0.000
E31 Polyglandular dysfunction
0.136 0.864 0.000
E20 Hypoparathyroidism
0.136 0.864 0.000
E53 Deficiency of other B group vitamins
0.130 0.869 0.000
E26.8 Other hyperaldosteronism
0.130 0.870 0.000
E26.1 Secondary hyperaldosteronism
0.130 0.870 0.000
E50.9 Vitamin A deficiency, unspecified
0.124 0.875 0.001
E50.8 Other manifestations of vitamin A deficiency
0.124 0.875 0.001
E50.7 Other ocular manifestations of vitamin A deficiency
0.124 0.875 0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.124 0.875 0.001
E50.5 Vitamin A deficiency with night blindness
0.124 0.875 0.001
E50.4 Vitamin A deficiency with keratomalacia
0.124 0.875 0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.124 0.875 0.001
E50.2 Vitamin A deficiency with corneal xerosis
0.124 0.875 0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.124 0.875 0.001
E50.0 Vitamin A deficiency with conjunctival xerosis
0.124 0.875 0.001
E63.9 Nutritional deficiency, unspecified
0.124 0.875 0.001
E63.8 Other specified nutritional deficiencies
0.124 0.875 0.001
E63.1 Imbalance of constituents of food intake
0.124 0.875 0.001
E63.0 Essential fatty acid [EFA] deficiency
0.124 0.875 0.001
E64.9 Sequelae of unspecified nutritional deficiency
0.124 0.875 0.001
E64.8 Sequelae of other nutritional deficiencies
0.124 0.875 0.001
E64.3 Sequelae of rickets
0.124 0.875 0.001
E64.2 Sequelae of vitamin C deficiency
0.124 0.875 0.001
E64.1 Sequelae of vitamin A deficiency
0.124 0.875 0.001
E64.0 Sequelae of protein-energy malnutrition
0.124 0.875 0.001
E61 Deficiency of other nutrient elements
0.120 0.879 0.001
E24.8 Other Cushing's syndrome
0.119 0.881 0.000
E24.2 Drug-induced Cushing's syndrome
0.119 0.881 0.000
E51.9 Thiamine deficiency, unspecified
0.117 0.882 0.001
E51.8 Other manifestations of thiamine deficiency
0.117 0.882 0.001
E51.1 Beriberi
0.117 0.882 0.001
E34.8 Other specified endocrine disorders
0.118 0.882 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.117 0.883 0.000
E24.3 Ectopic ACTH syndrome
0.117 0.883 0.000
E24.1 Nelson's syndrome
0.117 0.883 0.000
E34.3 Short stature, not elsewhere classified
0.116 0.884 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.115 0.885 0.000
E24.9 Cushing's syndrome, unspecified
0.112 0.888 0.000
E55 Vitamin D deficiency
0.112 0.888 0.001
M81.99 Osteoporosis, unspecified (Site unspecified)
0.110 0.890 0.000
E51.2 Wernicke's encephalopathy
0.108 0.892 0.001
E56.9 Vitamin deficiency, unspecified
0.107 0.892 0.001
E56.8 Deficiency of other vitamins
0.107 0.892 0.001
E56.0 Deficiency of vitamin E
0.107 0.892 0.001
E25.9 Adrenogenital disorder, unspecified
0.107 0.893 0.000
E25.8 Other adrenogenital disorders
0.107 0.893 0.000
E29.1 Testicular hypofunction
0.105 0.895 0.000
E04.0 Non-toxic diffuse goitre
0.103 0.896 0.001
E06.3 Autoimmune thyroiditis
0.103 0.897 0.000
E34.5 Androgen resistance syndrome
0.103 0.897 0.000
E34.4 Constitutional tall stature
0.103 0.897 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.103 0.897 0.000
E34.1 Other hypersecretion of intestinal hormones
0.103 0.897 0.000
E30.9 Disorder of puberty, unspecified
0.102 0.898 0.000
E30.8 Other disorders of puberty
0.102 0.898 0.000
E30.1 Precocious puberty
0.102 0.898 0.000
E30.0 Delayed puberty
0.102 0.898 0.000
E32.9 Disease of thymus, unspecified
0.102 0.898 0.000
E32.8 Other diseases of thymus
0.102 0.898 0.000
E32.1 Abscess of thymus
0.102 0.898 0.000
E32.0 Persistent hyperplasia of thymus
0.102 0.898 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.102 0.898 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.102 0.898 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.102 0.898 0.000
E29.8 Other testicular dysfunction
0.101 0.899 0.000
E29.0 Testicular hyperfunction
0.101 0.899 0.000
E53.9 Vitamin B deficiency, unspecified
0.100 0.899 0.000
E31.9 Polyglandular dysfunction, unspecified
0.098 0.902 0.000
E31.8 Other polyglandular dysfunction
0.098 0.902 0.000
E31.1 Polyglandular hyperfunction
0.098 0.902 0.000
E20.8 Other hypoparathyroidism
0.097 0.902 0.000
E20.1 Pseudohypoparathyroidism
0.097 0.902 0.000
E20.0 Idiopathic hypoparathyroidism
0.097 0.902 0.000
E22 Hyperfunction of pituitary gland
0.096 0.904 0.000
E29.9 Testicular dysfunction, unspecified
0.094 0.905 0.000
E53.1 Pyridoxine deficiency
0.094 0.906 0.000
E53.0 Riboflavin deficiency
0.094 0.906 0.000
E31.0 Autoimmune polyglandular failure
0.093 0.907 0.000
E61.2 Magnesium deficiency
0.091 0.908 0.001
E20.9 Hypoparathyroidism, unspecified
0.091 0.908 0.000
E61.9 Deficiency of nutrient element, unspecified
0.086 0.913 0.001
E61.8 Deficiency of other specified nutrient elements
0.086 0.913 0.001
E61.7 Deficiency of multiple nutrient elements
0.086 0.913 0.001
E61.6 Vanadium deficiency
0.086 0.913 0.001
E61.5 Molybdenum deficiency
0.086 0.913 0.001
E61.4 Chromium deficiency
0.086 0.913 0.001
E61.3 Manganese deficiency
0.086 0.913 0.001
E61.0 Copper deficiency
0.086 0.913 0.001
E27 Other disorders of adrenal gland
0.086 0.914 0.000
E56.1 Deficiency of vitamin K
0.084 0.915 0.001
E34.0 Carcinoid syndrome
0.084 0.916 0.000
E55.0 Rickets, active
0.080 0.919 0.001
E34.9 Endocrine disorder, unspecified
0.079 0.921 0.000
E22.1 Hyperprolactinaemia
0.078 0.922 0.000
E27.1 Primary adrenocortical insufficiency
0.076 0.924 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.069 0.931 0.000
E22.8 Other hyperfunction of pituitary gland
0.069 0.931 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.065 0.935 0.000
E23 Hypofunction and other disorders of pituitary gland
0.064 0.936 0.000
E28 Ovarian dysfunction
0.062 0.938 0.001
E27.5 Adrenomedullary hyperfunction
0.062 0.938 0.000
E27.0 Other adrenocortical overactivity
0.062 0.938 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.061 0.939 0.000
E04.1 Non-toxic single thyroid nodule
0.059 0.941 0.000
K90-K93 Other diseases of the digestive system
0.057 0.943 0.000
E27.2 Addisonian crisis
0.057 0.943 0.000
E66 Obesity
0.055 0.945 0.000
G56.2 Lesion of ulnar nerve
0.053 0.947 0.000
M81.9 Osteoporosis, unspecified
0.053 0.947 0.000
E27.8 Other specified disorders of adrenal gland
0.051 0.949 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.051 0.949 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.050 0.950 0.000
E23.2 Diabetes insipidus
0.047 0.952 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.047 0.953 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.046 0.954 0.000
E23.1 Drug-induced hypopituitarism
0.046 0.954 0.000
E21.4 Other specified disorders of parathyroid gland
0.046 0.954 0.000
E28.9 Ovarian dysfunction, unspecified
0.044 0.955 0.001
E28.8 Other ovarian dysfunction
0.044 0.955 0.001
E28.1 Androgen excess
0.044 0.955 0.001
E28.0 Oestrogen excess
0.044 0.955 0.001
M81.93 Osteoporosis, unspecified (Forearm)
0.044 0.955 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.044 0.956 0.000
E23.7 Disorder of pituitary gland, unspecified
0.042 0.958 0.000
E21.2 Other hyperparathyroidism
0.041 0.958 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.041 0.959 0.000
E66.0 Obesity due to excess calories
0.041 0.959 0.000
E04.9 Non-toxic goitre, unspecified
0.041 0.959 0.000
E66.1 Drug-induced obesity
0.040 0.960 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.039 0.961 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.039 0.961 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.038 0.962 0.000
E23.6 Other disorders of pituitary gland
0.036 0.964 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.034 0.966 0.000
E53.8 Deficiency of other specified B group vitamins
0.033 0.967 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.033 0.967 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.032 0.967 0.000
E27.9 Disorder of adrenal gland, unspecified
0.031 0.968 0.001
E22.0 Acromegaly and pituitary gigantism
0.030 0.969 0.001
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.030 0.970 0.000
K93.1 Megacolon in Chagas' disease
0.030 0.970 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.030 0.970 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.028 0.972 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.025 0.975 0.000
E11.9 Without complications
0.025 0.975 0.000
E28.3 Primary ovarian failure
0.023 0.976 0.001
E66.8 Other obesity
0.023 0.977 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.000 0.977 0.023
M81.98 Osteoporosis, unspecified (Other)
0.022 0.978 0.000
M81 Osteoporosis without pathological fracture
0.021 0.979 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.020 0.980 0.000
E61.1 Iron deficiency
0.018 0.980 0.002
E55.9 Vitamin D deficiency, unspecified
0.019 0.980 0.001
E28.2 Polycystic ovarian syndrome
0.018 0.981 0.001
E70-E90 Metabolic disorders
0.016 0.984 0.000
M81.8 Other osteoporosis
0.016 0.984 0.000
M81.0 Postmenopausal osteoporosis
0.016 0.984 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.015 0.985 0.000
E21.3 Hyperparathyroidism, unspecified
0.015 0.985 0.000
M81.6 Localised osteoporosis [Lequesne]
0.015 0.985 0.000
M81.5 Idiopathic osteoporosis
0.015 0.985 0.000
M81.1 Postoophorectomy osteoporosis
0.015 0.985 0.000
M81.2 Osteoporosis of disuse
0.015 0.985 0.000
E73 Lactose intolerance
0.014 0.986 0.000
E85 Amyloidosis
0.014 0.986 0.000
E84 Cystic fibrosis
0.014 0.986 0.000
E73.9 Lactose intolerance, unspecified
0.013 0.987 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.013 0.987 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.013 0.987 0.000
M81.4 Drug-induced osteoporosis
0.013 0.987 0.000
E23.0 Hypopituitarism
0.012 0.987 0.000
H61.2 Impacted cerumen
0.013 0.987 0.000
E77 Disorders of glycoprotein metabolism
0.013 0.987 0.000
E21.0 Primary hyperparathyroidism
0.013 0.987 0.000
E72 Other disorders of amino-acid metabolism
0.013 0.987 0.000
M81.80 Other osteoporosis (Multiple sites)
0.012 0.988 0.000
E70 Disorders of aromatic amino-acid metabolism
0.012 0.988 0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.012 0.988 0.000
E76 Disorders of glycosaminoglycan metabolism
0.012 0.988 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.012 0.988 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.012 0.988 0.000
Z88.5 Personal history of allergy to narcotic agent
0.012 0.988 0.000
E79 Disorders of purine and pyrimidine metabolism
0.012 0.988 0.000
E84.9 Cystic fibrosis, unspecified
0.012 0.988 0.000
M81.89 Other osteoporosis (Site unspecified)
0.011 0.988 0.000
M81.88 Other osteoporosis (Other)
0.011 0.988 0.000
M81.87 Other osteoporosis (Ankle and foot)
0.011 0.988 0.000
M81.86 Other osteoporosis (Lower leg)
0.011 0.988 0.000
M81.85 Other osteoporosis (Pelvic region and thigh)
0.011 0.988 0.000
M81.84 Other osteoporosis (Hand)
0.011 0.988 0.000
M81.83 Other osteoporosis (Forearm)
0.011 0.988 0.000
M81.82 Other osteoporosis (Upper arm)
0.011 0.988 0.000
M81.81 Other osteoporosis (Shoulder region)
0.011 0.988 0.000
E85.9 Amyloidosis, unspecified
0.011 0.988 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.011 0.988 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.011 0.988 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.011 0.988 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.011 0.988 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.011 0.988 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.011 0.988 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.011 0.988 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.011 0.988 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.011 0.988 0.000
E88 Other metabolic disorders
0.011 0.989 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.011 0.989 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.011 0.989 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.011 0.989 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.011 0.989 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.011 0.989 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.011 0.989 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.011 0.989 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.011 0.989 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.011 0.989 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.011 0.989 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.011 0.989 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.011 0.989 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.011 0.989 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.011 0.989 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.011 0.989 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.011 0.989 0.000
M81.59 Idiopathic osteoporosis (Site unspecified)
0.011 0.989 0.000
M81.58 Idiopathic osteoporosis (Other)
0.011 0.989 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.011 0.989 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.011 0.989 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.011 0.989 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.011 0.989 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.011 0.989 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.011 0.989 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.011 0.989 0.000
M81.50 Idiopathic osteoporosis (Multiple sites)
0.011 0.989 0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.011 0.989 0.000
M81.68 Localized osteoporosis [Lequesne] (Other)
0.011 0.989 0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.011 0.989 0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.011 0.989 0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.011 0.989 0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.011 0.989 0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.011 0.989 0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)
0.011 0.989 0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)
0.011 0.989 0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)
0.011 0.989 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.011 0.989 0.000
M81.28 Osteoporosis of disuse (Other)
0.011 0.989 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.011 0.989 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.011 0.989 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.011 0.989 0.000
M81.24 Osteoporosis of disuse (Hand)
0.011 0.989 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.011 0.989 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.011 0.989 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.011 0.989 0.000
E85.8 Other amyloidosis
0.011 0.989 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.011 0.989 0.000
E85.3 Secondary systemic amyloidosis
0.011 0.989 0.000
E74 Other disorders of carbohydrate metabolism
0.010 0.989 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.011 0.989 0.000
E73.8 Other lactose intolerance
0.010 0.989 0.000
E73.1 Secondary lactase deficiency
0.010 0.989 0.000
E73.0 Congenital lactase deficiency
0.010 0.989 0.000
E85.4 Organ-limited amyloidosis
0.010 0.989 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.010 0.990 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.010 0.990 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.010 0.990 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.010 0.990 0.000
G56 Mononeuropathies of upper limb
0.010 0.990 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.010 0.990 0.000
E88.3 Tumour lysis syndrome
0.010 0.990 0.000
E77.8 Other disorders of glycoprotein metabolism
0.010 0.990 0.000
E84.8 Cystic fibrosis with other manifestations
0.010 0.990 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.010 0.990 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.010 0.990 0.000
E72.0 Disorders of amino-acid transport
0.010 0.990 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.990 0.010
I34.0 Mitral (valve) insufficiency
0.010 0.990 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.010 0.990 0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.009 0.990 0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.009 0.990 0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.009 0.990 0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.009 0.990 0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.009 0.990 0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.009 0.990 0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.009 0.990 0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.009 0.990 0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.009 0.990 0.000
M81.48 Drug-induced osteoporosis (Other)
0.009 0.990 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.009 0.990 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.009 0.990 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.009 0.990 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.009 0.990 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.009 0.990 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.009 0.990 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.009 0.990 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.009 0.991 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.009 0.991 0.000
E77.1 Defects in glycoprotein degradation
0.009 0.991 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.009 0.991 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.009 0.991 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.009 0.991 0.000
E72.5 Disorders of glycine metabolism
0.009 0.991 0.000
E72.4 Disorders of ornithine metabolism
0.009 0.991 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.009 0.991 0.000
E72.2 Disorders of urea cycle metabolism
0.009 0.991 0.000
E74.0 Glycogen storage disease
0.009 0.991 0.000
E70.3 Albinism
0.009 0.991 0.000
E88.2 Lipomatosis, not elsewhere classified
0.009 0.991 0.000
G56.4 Causalgia
0.009 0.991 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.009 0.991 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.009 0.991 0.000
E70.2 Disorders of tyrosine metabolism
0.009 0.991 0.000
E70.1 Other hyperphenylalaninaemias
0.009 0.991 0.000
E70.0 Classical phenylketonuria
0.009 0.991 0.000
E88.8 Other specified metabolic disorders
0.009 0.991 0.000
E71.3 Disorders of fatty-acid metabolism
0.009 0.991 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.009 0.991 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.009 0.991 0.000
E71.0 Maple-syrup-urine disease
0.009 0.991 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.009 0.991 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.009 0.991 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.009 0.991 0.000
E76.2 Other mucopolysaccharidoses
0.009 0.991 0.000
E76.1 Mucopolysaccharidosis, type II
0.009 0.991 0.000
E76.0 Mucopolysaccharidosis, type I
0.009 0.991 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.008 0.991 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.008 0.991 0.000
E79.1 Lesch-Nyhan syndrome
0.008 0.991 0.000
G56.3 Lesion of radial nerve
0.008 0.992 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.008 0.992 0.000
H61 Other disorders of external ear
0.008 0.992 0.000
E88.9 Metabolic disorder, unspecified
0.008 0.992 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.008 0.992 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.008 0.992 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.008 0.992 0.000
E74.2 Disorders of galactose metabolism
0.008 0.992 0.000
E74.1 Disorders of fructose metabolism
0.008 0.992 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.992 0.008
E75.2 Other sphingolipidosis
0.008 0.992 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.992 0.008
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.007 0.992 0.000
E75.6 Lipid storage disorder, unspecified
0.007 0.992 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.007 0.992 0.000
E75.3 Sphingolipidosis, unspecified
0.007 0.992 0.000
E75.1 Other gangliosidosis
0.007 0.992 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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