TreeWAS – Variant ID: rs11127485

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	0.000	0.000	1.000
E66 Obesity	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.001	0.999
E66.8 Other obesity	0.000	0.003	0.997
E11.9 Without complications	0.000	0.005	0.995
E11.4 With neurological complications	0.000	0.007	0.993
E10-E14 Diabetes mellitus	0.000	0.031	0.969
E11.2 With renal complications	0.000	0.037	0.963
E65-E68 Obesity and other hyperalimentation	0.000	0.039	0.961
E11.3 With ophthalmic complications	0.000	0.066	0.934
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.090	0.910
E10 Insulin-dependent diabetes mellitus	0.000	0.142	0.858
E11.5 With peripheral circulatory complications	0.000	0.170	0.830
E65 Localised adiposity	0.000	0.189	0.811
E66.0 Obesity due to excess calories	0.000	0.203	0.797
E11.8 With unspecified complications	0.000	0.204	0.795
E10.9 Without complications	0.000	0.232	0.768
E14 Unspecified diabetes mellitus	0.000	0.246	0.754
E66.1 Drug-induced obesity	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.284	0.716
E12 Malnutrition-related diabetes mellitus	0.000	0.305	0.695
E10.2 With renal complications	0.000	0.310	0.690
E10.4 With neurological complications	0.000	0.310	0.690
E67 Other hyperalimentation	0.000	0.311	0.689
E68 Sequelae of hyperalimentation	0.000	0.311	0.689
E10.0 With coma	0.000	0.319	0.681
E10.8 With unspecified complications	0.000	0.326	0.674
E14.3 With ophthalmic complications	0.000	0.329	0.671
E11.1 With ketoacidosis	0.000	0.330	0.670
E13 Other specified diabetes mellitus	0.000	0.339	0.661
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.339	0.661
E11.6 With other specified complications	0.000	0.355	0.645
E10.5 With peripheral circulatory complications	0.000	0.381	0.619
E10.7 With multiple complications	0.000	0.385	0.615
E50-E64 Other nutritional deficiencies	0.000	0.400	0.600
E11.0 With coma	0.000	0.408	0.591
E10.6 With other specified complications	0.000	0.413	0.586
E61 Deficiency of other nutrient elements	0.000	0.451	0.549
E14.7 With multiple complications	0.000	0.459	0.540
E14.6 With other specified complications	0.000	0.459	0.540
E14.5 With peripheral circulatory complications	0.000	0.459	0.540
E14.2 Withrenal complications	0.000	0.459	0.540
E14.1 With ketoacidosis	0.000	0.459	0.540
E14.0 With coma	0.000	0.459	0.540
E14.8 With unspecified complications	0.000	0.464	0.536
E61.1 Iron deficiency	0.000	0.486	0.514
E12.9 Without complications	0.000	0.502	0.498
E12.8 With unspecified complications	0.000	0.502	0.498
E12.7 With multiple complications	0.000	0.502	0.498
E12.6 With other specified complications	0.000	0.502	0.498
E12.5 With peripheral circulatory complications	0.000	0.502	0.498
E12.4 With neurological complications	0.000	0.502	0.498
E12.3 With ophthalmic complications	0.000	0.502	0.498
E12.2 With renal complications	0.000	0.502	0.498
E12.1 With ketoacidosis	0.000	0.502	0.498
E12.0 With coma	0.000	0.502	0.498
E67.8 Other specified hyperalimentation	0.000	0.506	0.494
E67.3 Hypervitaminosis D	0.000	0.506	0.494
E67.2 Megavitamin-B6 syndrome	0.000	0.506	0.494
E67.1 Hypercarotenaemia	0.000	0.506	0.494
E67.0 Hypervitaminosis A	0.000	0.506	0.494
E10.3 With ophthalmic complications	0.000	0.507	0.493
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.512	0.488
E40-E46 Malnutrition	0.000	0.522	0.478
E13.8 With unspecified complications	0.000	0.526	0.474
E13.7 With multiple complications	0.000	0.526	0.474
E13.6 With other specified complications	0.000	0.526	0.474
E13.5 With peripheral circulatory complications	0.000	0.526	0.474
E13.4 With neurological complications	0.000	0.526	0.474
E13.3 With ophthalmic complications	0.000	0.526	0.474
E13.2 With renal complications	0.000	0.526	0.474
E13.1 With ketoacidosis	0.000	0.526	0.474
E13.0 With coma	0.000	0.526	0.474
E14.9 Without complications	0.000	0.533	0.467
E14.4 With neurological complications	0.000	0.535	0.465
E13.9 Without complications	0.000	0.559	0.441
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.569	0.430
E63 Other nutritional deficiencies	0.000	0.569	0.430
E56 Other vitamin deficiencies	0.000	0.569	0.430
E50 Vitamin A deficiency	0.000	0.569	0.430
E60 Dietary zinc deficiency	0.000	0.569	0.430
E59 Dietary selenium deficiency	0.000	0.569	0.430
E58 Dietary calcium deficiency	0.000	0.569	0.430
E54 Ascorbic acid deficiency	0.000	0.569	0.430
E52 Niacin deficiency [pellagra]	0.000	0.569	0.430
E51 Thiamine deficiency	0.000	0.592	0.408
E61.9 Deficiency of nutrient element, unspecified	0.000	0.606	0.394
E61.8 Deficiency of other specified nutrient elements	0.000	0.606	0.394
E61.7 Deficiency of multiple nutrient elements	0.000	0.606	0.394
E61.6 Vanadium deficiency	0.000	0.606	0.394
E61.5 Molybdenum deficiency	0.000	0.606	0.394
E61.4 Chromium deficiency	0.000	0.606	0.394
E61.3 Manganese deficiency	0.000	0.606	0.394
E61.0 Copper deficiency	0.000	0.606	0.394
E61.2 Magnesium deficiency	0.000	0.611	0.388
E10.1 With ketoacidosis	0.000	0.635	0.365
E15 Nondiabetic hypoglycaemic coma	0.000	0.650	0.350
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.657	0.343
E45 Retarded development following protein-energy malnutrition	0.000	0.657	0.343
E43 Unspecified severe protein-energy malnutrition	0.000	0.657	0.343
E42 Marasmic kwashiorkor	0.000	0.657	0.343
E41 Nutritional marasmus	0.000	0.657	0.343
E40 Kwashiorkor	0.000	0.657	0.343
E55 Vitamin D deficiency	0.000	0.688	0.311
E50.9 Vitamin A deficiency, unspecified	0.000	0.691	0.309
E50.8 Other manifestations of vitamin A deficiency	0.000	0.691	0.309
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.691	0.309
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.691	0.309
E50.5 Vitamin A deficiency with night blindness	0.000	0.691	0.309
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.691	0.309
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.691	0.309
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.691	0.309
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.691	0.309
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.691	0.309
E56.9 Vitamin deficiency, unspecified	0.000	0.691	0.309
E56.8 Deficiency of other vitamins	0.000	0.691	0.309
E56.1 Deficiency of vitamin K	0.000	0.691	0.309
E56.0 Deficiency of vitamin E	0.000	0.691	0.309
E63.9 Nutritional deficiency, unspecified	0.000	0.691	0.309
E63.8 Other specified nutritional deficiencies	0.000	0.691	0.309
E63.1 Imbalance of constituents of food intake	0.000	0.691	0.309
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.691	0.309
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.691	0.309
E64.8 Sequelae of other nutritional deficiencies	0.000	0.691	0.309
E64.3 Sequelae of rickets	0.000	0.691	0.309
E64.2 Sequelae of vitamin C deficiency	0.000	0.691	0.309
E64.1 Sequelae of vitamin A deficiency	0.000	0.691	0.309
E64.0 Sequelae of protein-energy malnutrition	0.000	0.691	0.309
I10 Essential (primary) hypertension	0.000	0.692	0.308
E51.9 Thiamine deficiency, unspecified	0.000	0.707	0.293
E51.8 Other manifestations of thiamine deficiency	0.000	0.707	0.293
E51.1 Beriberi	0.000	0.707	0.293
E51.2 Wernicke's encephalopathy	0.000	0.729	0.270
E44.1 Mild protein-energy malnutrition	0.000	0.754	0.246
E44.0 Moderate protein-energy malnutrition	0.000	0.754	0.246
E55.0 Rickets, active	0.000	0.776	0.223
E53 Deficiency of other B group vitamins	0.001	0.779	0.220
E16 Other disorders of pancreatic internal secretion	0.000	0.814	0.186
E46 Unspecified protein-energy malnutrition	0.001	0.831	0.168
E53.1 Pyridoxine deficiency	0.001	0.842	0.158
E53.0 Riboflavin deficiency	0.001	0.842	0.158
I10-I15 Hypertensive diseases	0.000	0.846	0.154
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.866	0.134
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.866	0.134
E16.4 Abnormal secretion of gastrin	0.000	0.866	0.134
E16.3 Increased secretion of glucagon	0.000	0.866	0.134
E53.9 Vitamin B deficiency, unspecified	0.001	0.869	0.131
E16.1 Other hypoglycaemia	0.000	0.872	0.127
I12 Hypertensive renal disease	0.000	0.874	0.126
I15 Secondary hypertension	0.000	0.880	0.120
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.884	0.116
I13 Hypertensive heart and renal disease	0.000	0.889	0.111
I12.9 Hypertensive renal disease without renal failure	0.000	0.892	0.108
E55.9 Vitamin D deficiency, unspecified	0.000	0.896	0.104
I84.6 Residual haemorrhoidal skin tags	0.000	0.901	0.099
I15.1 Hypertension secondary to other renal disorders	0.000	0.902	0.098
I11 Hypertensive heart disease	0.000	0.909	0.091
I15.8 Other secondary hypertension	0.000	0.914	0.086
I15.2 Hypertension secondary to endocrine disorders	0.000	0.914	0.086
I15.0 Renovascular hypertension	0.000	0.914	0.086
I12.0 Hypertensive renal disease with renal failure	0.000	0.917	0.083
I15.9 Seconday hypertension, unspecified	0.000	0.917	0.083
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.920	0.080
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.920	0.080
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.920	0.080
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.920	0.080
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.937	0.063
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.952	0.048
Z86.4 Personal history of psychoactive substance abuse	0.000	0.954	0.046
G56.0 Carpal tunnel syndrome	0.000	0.955	0.045
E16.2 Hypoglycaemia, unspecified	0.000	0.959	0.041
E00-E07 Disorders of thyroid gland	0.000	0.960	0.039
J22 Unspecified acute lower respiratory infection	0.000	0.968	0.032
E53.8 Deficiency of other specified B group vitamins	0.001	0.969	0.030
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.971	0.028
E00 Congenital iodine-deficiency syndrome	0.000	0.971	0.028
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.971	0.028
K76.8 Other specified diseases of liver	0.027	0.973	0.000
E07 Other disorders of thyroid	0.000	0.974	0.026
I84.4 External haemorrhoids with other complications	0.000	0.976	0.024
I85.9 Oesophageal varices without bleeding	0.000	0.976	0.024
I84 Haemorrhoids	0.000	0.976	0.024
I85 Oesophageal varices	0.000	0.976	0.023
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.977	0.023
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.978	0.022
I89.0 Lymphoedema, not elsewhere classified	0.000	0.979	0.021
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.979	0.021
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.979	0.021
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.979	0.021
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.979	0.021
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.979	0.021
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.979	0.021
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.979	0.021
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.979	0.021
O48 Prolonged pregnancy	0.021	0.979	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.979	0.021
I82 Other venous embolism and thrombosis	0.000	0.980	0.020
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.980	0.020
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.980	0.020
E07.9 Disorder of thyroid, unspecified	0.000	0.980	0.019
I84.0 Internal thrombosed haemorrhoids	0.000	0.981	0.019
E20-E35 Disorders of other endocrine glands	0.003	0.981	0.016
E07.1 Dyshormogenetic goitre	0.000	0.981	0.018
E07.0 Hypersecretion of calcitonin	0.000	0.981	0.018
I81 Portal vein thrombosis	0.000	0.982	0.018
I82.8 Embolism and thrombosis of other specified veins	0.000	0.982	0.018
S83.2 Tear of meniscus, current	0.000	0.982	0.018
I85.0 Oesophageal varices with bleeding	0.000	0.983	0.017
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.983	0.017
E06 Thyroiditis	0.000	0.983	0.017
I86 Varicose veins of other sites	0.000	0.983	0.016
I89.1 Lymphangitis	0.000	0.984	0.016
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.984	0.016
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.985	0.015
I84.1 Internal haemorrhoids with other complications	0.000	0.985	0.015
E70-E90 Metabolic disorders	0.000	0.985	0.015
I82.3 Embolism and thrombosis of renal vein	0.000	0.985	0.015
I82.1 Thrombophlebitis migrans	0.000	0.985	0.015
I82.0 Budd-Chiari syndrome	0.000	0.985	0.015
E07.8 Other specified disorders of thyroid	0.000	0.986	0.014
I86.8 Varicose veins of other specified sites	0.000	0.986	0.014
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.986	0.011
E32 Diseases of thymus	0.002	0.986	0.011
E31 Polyglandular dysfunction	0.002	0.986	0.011
E30 Disorders of puberty, not elsewhere classified	0.002	0.986	0.011
E34 Other endocrine disorders	0.002	0.986	0.012
I87 Other disorders of veins	0.000	0.987	0.013
E20 Hypoparathyroidism	0.002	0.987	0.011
I88 Nonspecific lymphadenitis	0.001	0.987	0.013
I82.2 Embolism and thrombosis of vena cava	0.000	0.987	0.013
E26 Hyperaldosteronism	0.002	0.987	0.010
E25 Adrenogenital disorders	0.003	0.987	0.010
E06.5 Other chronic thyroiditis	0.000	0.987	0.012
E06.4 Drug-induced thyroiditis	0.000	0.987	0.012
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.987	0.012
E06.1 Subacute thyroiditis	0.000	0.987	0.012
E06.0 Acute thyroiditis	0.000	0.987	0.012
I84.3 External thrombosed haemorrhoids	0.000	0.988	0.012
I86.2 Pelvic varices	0.000	0.988	0.012
E85 Amyloidosis	0.000	0.988	0.012
E29 Testicular dysfunction	0.002	0.988	0.010
Chapter IX Diseases of the circulatory system	0.000	0.988	0.012
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.988	0.012
I86.3 Vulval varices	0.000	0.988	0.012
I86.0 Sublingual varices	0.000	0.988	0.012
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.988	0.012
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.988	0.012
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.988	0.012
I86.4 Gastric varices	0.000	0.988	0.012
J20-J22 Other acute lower respiratory infections	0.000	0.988	0.012
G56 Mononeuropathies of upper limb	0.000	0.988	0.012
E28 Ovarian dysfunction	0.002	0.988	0.009
H54.7 Unspecified visual loss	0.000	0.989	0.011
I50.0 Congestive heart failure	0.000	0.989	0.011
E84 Cystic fibrosis	0.000	0.989	0.011
E79 Disorders of purine and pyrimidine metabolism	0.000	0.989	0.011
E77 Disorders of glycoprotein metabolism	0.000	0.989	0.011
E76 Disorders of glycosaminoglycan metabolism	0.000	0.989	0.011
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.989	0.011
E72 Other disorders of amino-acid metabolism	0.000	0.989	0.011
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.989	0.011
E70 Disorders of aromatic amino-acid metabolism	0.000	0.989	0.011
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.989	0.011
E73 Lactose intolerance	0.000	0.989	0.011
E24 Cushing's syndrome	0.003	0.989	0.008
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.989	0.011
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.989	0.011
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.989	0.011
E34.9 Endocrine disorder, unspecified	0.001	0.989	0.009
G59.0 Diabetic mononeuropathy	0.000	0.990	0.010
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.990	0.010
I87.1 Compression of vein	0.000	0.990	0.010
E30.9 Disorder of puberty, unspecified	0.002	0.990	0.008
E30.8 Other disorders of puberty	0.002	0.990	0.008
E30.1 Precocious puberty	0.002	0.990	0.008
E30.0 Delayed puberty	0.002	0.990	0.008
E31.9 Polyglandular dysfunction, unspecified	0.002	0.990	0.008
E31.8 Other polyglandular dysfunction	0.002	0.990	0.008
E31.1 Polyglandular hyperfunction	0.002	0.990	0.008
E31.0 Autoimmune polyglandular failure	0.002	0.990	0.008
E32.9 Disease of thymus, unspecified	0.002	0.990	0.008
E32.8 Other diseases of thymus	0.002	0.990	0.008
E32.1 Abscess of thymus	0.002	0.990	0.008
E32.0 Persistent hyperplasia of thymus	0.002	0.990	0.008
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.990	0.008
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.990	0.008
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.990	0.008
E22 Hyperfunction of pituitary gland	0.002	0.990	0.008
E34.5 Androgen resistance syndrome	0.001	0.990	0.009
E34.4 Constitutional tall stature	0.001	0.990	0.009
E34.3 Short stature, not elsewhere classified	0.001	0.990	0.009
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.990	0.009
E34.1 Other hypersecretion of intestinal hormones	0.001	0.990	0.009
E34.0 Carcinoid syndrome	0.001	0.990	0.009
E85.4 Organ-limited amyloidosis	0.000	0.990	0.010
I87.9 Disorder of vein, unspecified	0.000	0.990	0.010
I87.0 Postphlebitic syndrome	0.000	0.990	0.010
E74 Other disorders of carbohydrate metabolism	0.000	0.990	0.010
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.990	0.010
E03 Other hypothyroidism	0.000	0.990	0.010
E20.8 Other hypoparathyroidism	0.002	0.990	0.008
E20.1 Pseudohypoparathyroidism	0.002	0.990	0.008
E20.0 Idiopathic hypoparathyroidism	0.002	0.990	0.008
I88.8 Other nonspecific lymphadenitis	0.001	0.990	0.009
I88.1 Chronic lymphadenitis, except mesenteric	0.001	0.990	0.009
I88.0 Nonspecific mesenteric lymphadenitis	0.001	0.990	0.009
E85.9 Amyloidosis, unspecified	0.000	0.990	0.009
E26.9 Hyperaldosteronism, unspecified	0.002	0.991	0.008
E26.8 Other hyperaldosteronism	0.002	0.991	0.008
E26.1 Secondary hyperaldosteronism	0.002	0.991	0.008
E23 Hypofunction and other disorders of pituitary gland	0.004	0.991	0.005
E34.8 Other specified endocrine disorders	0.002	0.991	0.008
E25.9 Adrenogenital disorder, unspecified	0.002	0.991	0.007
E25.8 Other adrenogenital disorders	0.002	0.991	0.007
E87.5 Hyperkalaemia	0.000	0.991	0.009
N99.0 Postprocedural renal failure	0.000	0.991	0.009
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.991	0.009
N99.5 Malfunction of external stoma of urinary tract	0.000	0.991	0.009
E20.9 Hypoparathyroidism, unspecified	0.002	0.991	0.007
E85.8 Other amyloidosis	0.000	0.991	0.009
E85.3 Secondary systemic amyloidosis	0.000	0.991	0.009
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.991	0.009
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.991	0.009
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.991	0.009
G56.3 Lesion of radial nerve	0.000	0.991	0.009
E29.9 Testicular dysfunction, unspecified	0.002	0.991	0.007
E29.8 Other testicular dysfunction	0.002	0.991	0.007
E29.0 Testicular hyperfunction	0.002	0.991	0.007
N99.2 Postprocedural adhesions of vagina	0.000	0.991	0.009
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.991	0.009
E06.3 Autoimmune thyroiditis	0.000	0.991	0.008
E78.0 Pure hypercholesterolaemia	0.000	0.991	0.009
G35 Multiple sclerosis	0.009	0.991	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.991	0.009
G56.8 Other mononeuropathies of upper limb	0.000	0.991	0.009
Z86 Personal history of certain other diseases	0.000	0.991	0.009
I00-I02 Acute rheumatic fever	0.000	0.991	0.008
E28.9 Ovarian dysfunction, unspecified	0.002	0.991	0.007
E28.8 Other ovarian dysfunction	0.002	0.991	0.007
E28.1 Androgen excess	0.002	0.991	0.007
E28.0 Oestrogen excess	0.002	0.991	0.007
N99.1 Postprocedural urethral stricture	0.000	0.991	0.008
G56.1 Other lesions of median nerve	0.000	0.991	0.008
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.992	0.006
J21 Acute bronchiolitis	0.000	0.992	0.008
E06.9 Thyroiditis, unspecified	0.001	0.992	0.008
E26.0 Primary hyperaldosteronism	0.002	0.992	0.006
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.992	0.008
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.992	0.008
E70.3 Albinism	0.000	0.992	0.008
E70.2 Disorders of tyrosine metabolism	0.000	0.992	0.008
E70.1 Other hyperphenylalaninaemias	0.000	0.992	0.008
E70.0 Classical phenylketonuria	0.000	0.992	0.008
E71.3 Disorders of fatty-acid metabolism	0.000	0.992	0.008
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.992	0.008
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.992	0.008
E71.0 Maple-syrup-urine disease	0.000	0.992	0.008
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.992	0.008
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.992	0.008
E72.5 Disorders of glycine metabolism	0.000	0.992	0.008
E72.4 Disorders of ornithine metabolism	0.000	0.992	0.008
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.992	0.008
E72.2 Disorders of urea cycle metabolism	0.000	0.992	0.008
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.992	0.008
E72.0 Disorders of amino-acid transport	0.000	0.992	0.008
E75.6 Lipid storage disorder, unspecified	0.000	0.992	0.008
E75.5 Other lipid storage disorders	0.000	0.992	0.008
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.992	0.008
E75.3 Sphingolipidosis, unspecified	0.000	0.992	0.008
E75.2 Other sphingolipidosis	0.000	0.992	0.008
E75.1 Other gangliosidosis	0.000	0.992	0.008
E75.0 GM2 gangliosidosis	0.000	0.992	0.008
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.992	0.008
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.992	0.008
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.992	0.008
E76.2 Other mucopolysaccharidoses	0.000	0.992	0.008
E76.1 Mucopolysaccharidosis, type II	0.000	0.992	0.008
E76.0 Mucopolysaccharidosis, type I	0.000	0.992	0.008
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.992	0.008
E77.8 Other disorders of glycoprotein metabolism	0.000	0.992	0.008
E77.1 Defects in glycoprotein degradation	0.000	0.992	0.008
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.992	0.008
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.992	0.008
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.992	0.008
E79.1 Lesch-Nyhan syndrome	0.000	0.992	0.008
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.992	0.008
E84.9 Cystic fibrosis, unspecified	0.000	0.992	0.008
E84.8 Cystic fibrosis with other manifestations	0.000	0.992	0.008
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.992	0.008
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.992	0.008
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.992	0.006
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.992	0.008
E73.8 Other lactose intolerance	0.000	0.992	0.008
E73.1 Secondary lactase deficiency	0.000	0.992	0.008
E73.0 Congenital lactase deficiency	0.000	0.992	0.008
E24.8 Other Cushing's syndrome	0.002	0.992	0.006
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.992	0.006
E24.3 Ectopic ACTH syndrome	0.002	0.992	0.006
E24.1 Nelson's syndrome	0.002	0.992	0.006
E78.5 Hyperlipidaemia, unspecified	0.000	0.992	0.008
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.992	0.008
E78.1 Pure hyperglyceridaemia	0.000	0.992	0.008
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.992	0.008
G56.9 Mononeuropathy of upper limb, unspecified	0.000	0.992	0.008
E78.6 Lipoprotein deficiency	0.000	0.992	0.008
E78.3 Hyperchylomicronaemia	0.000	0.992	0.008
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.992	0.008
J20 Acute bronchitis	0.000	0.992	0.008
E73.9 Lactose intolerance, unspecified	0.000	0.992	0.008
G56.4 Causalgia	0.000	0.992	0.008
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.992	0.008
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.992	0.008
E24.0 Pituitary-dependent Cushing's disease	0.002	0.992	0.006
H54 Blindness and low vision	0.000	0.992	0.008
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.992	0.008
E05.8 Other thyrotoxicosis	0.000	0.992	0.007
E05.5 Thyroid crisis or storm	0.000	0.992	0.007
E05.4 Thyrotoxicosis factitia	0.000	0.992	0.007
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.992	0.007
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.992	0.007
E28.2 Polycystic ovarian syndrome	0.001	0.992	0.006
G47.3 Sleep apnoea	0.000	0.992	0.008
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.992	0.007
I05-I09 Chronic rheumatic heart diseases	0.000	0.992	0.008
E78.4 Other hyperlipidaemia	0.000	0.992	0.007
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.992	0.007
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.992	0.006
E22.8 Other hyperfunction of pituitary gland	0.002	0.992	0.006
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.992	0.008
I84.5 External haemorrhoids without complication	0.000	0.993	0.007
I86.1 Scrotal varices	0.000	0.993	0.007
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.993	0.007
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.993	0.007
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.993	0.007
E74.2 Disorders of galactose metabolism	0.000	0.993	0.007
E74.1 Disorders of fructose metabolism	0.000	0.993	0.007
E74.0 Glycogen storage disease	0.000	0.993	0.007
E29.1 Testicular hypofunction	0.002	0.993	0.006
E03.5 Myxoedema coma	0.000	0.993	0.007
E03.4 Atrophy of thyroid (acquired)	0.000	0.993	0.007
E03.3 Postinfectious hypothyroidism	0.000	0.993	0.007
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.993	0.007
H54.9 Unspecified visual impairment (binocular)	0.000	0.993	0.007
E88 Other metabolic disorders	0.000	0.993	0.007
E24.9 Cushing's syndrome, unspecified	0.002	0.993	0.005
N80.9 Endometriosis, unspecified	0.007	0.993	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.993	0.007
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.993	0.007
E24.2 Drug-induced Cushing's syndrome	0.003	0.993	0.004
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.993	0.007
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.993	0.004
E23.1 Drug-induced hypopituitarism	0.003	0.993	0.004
E28.3 Primary ovarian failure	0.002	0.993	0.005
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.993	0.007
G43.1 Migraine with aura [classical migraine]	0.000	0.993	0.007
E27 Other disorders of adrenal gland	0.003	0.993	0.004
E23.6 Other disorders of pituitary gland	0.002	0.993	0.005
E23.7 Disorder of pituitary gland, unspecified	0.003	0.993	0.004
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.993	0.007
E22.0 Acromegaly and pituitary gigantism	0.002	0.993	0.005
S83.3 Tear of articular cartilage of knee, current	0.000	0.993	0.007
S83.1 Dislocation of knee	0.000	0.993	0.007
S83.0 Dislocation of patella	0.000	0.993	0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.993	0.005
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.993	0.007
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.993	0.007
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.993	0.006
I09 Other rheumatic heart diseases	0.000	0.993	0.006
E03.1 Congenital hypothyroidism without goitre	0.000	0.993	0.006
I87.8 Other specified disorders of veins	0.000	0.993	0.006
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.993	0.007
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.994	0.006
I02 Rheumatic chorea	0.000	0.994	0.006
I01 Rheumatic fever with heart involvement	0.000	0.994	0.006
G40-G47 Episodic and paroxysmal disorders	0.000	0.994	0.006
E22.1 Hyperprolactinaemia	0.002	0.994	0.004
E21.4 Other specified disorders of parathyroid gland	0.002	0.994	0.004
E21.2 Other hyperparathyroidism	0.002	0.994	0.004
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.994	0.006
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.994	0.006
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.994	0.006
G43 Migraine	0.000	0.994	0.006
G47 Sleep disorders	0.000	0.994	0.006
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.994	0.006
H54.0 Blindness, both eyes	0.000	0.994	0.006
S83.7 Injury to multiple structures of knee	0.000	0.994	0.006
E23.2 Diabetes insipidus	0.004	0.994	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.994	0.004
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.994	0.006
E03.8 Other specified hypothyroidism	0.000	0.994	0.006
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.994	0.006
E80.6 Other disorders of bilirubin metabolism	0.000	0.994	0.006
E80.5 Crigler-Najjar syndrome	0.000	0.994	0.006
E80.3 Defects of catalase and peroxydase	0.000	0.994	0.006
E80.1 Porphyria cutanea tarda	0.000	0.994	0.006
E80.0 Hereditary erythropoietic porphyria	0.000	0.994	0.006
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.994	0.004
J20.7 Acute bronchitis due to echovirus	0.000	0.994	0.006
J20.6 Acute bronchitis due to rhinovirus	0.000	0.994	0.006
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations