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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117681218
log Bayes Factor = 15.1496
Chromosome 19   position 21,045,381  (GRCh37) Explore rs117681218 on Ensembl!
Variant rs117681218 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
I50 Heart failure
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
B95-B98 Bacterial, viral and other infectious agents
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
I24 Other acute ischaemic heart diseases
0.983 0.017 0.000
E10-E14 Diabetes mellitus
0.974 0.026 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.972 0.028 0.000
I35 Nonrheumatic aortic valve disorders
0.971 0.029 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.967 0.033 0.000
I50.1 Left ventricular failure
0.962 0.038 0.000
I25 Chronic ischaemic heart disease
0.962 0.038 0.000
Chapter V Mental and behavioural disorders
0.958 0.042 0.000
I50.0 Congestive heart failure
0.957 0.043 0.000
I20 Angina pectoris
0.954 0.046 0.000
E11 Non-insulin-dependent diabetes mellitus
0.951 0.049 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.950 0.050 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.947 0.053 0.000
J09-J18 Influenza and pneumonia
0.943 0.057 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.942 0.058 0.000
I05-I09 Chronic rheumatic heart diseases
0.940 0.060 0.000
I22 Subsequent myocardial infarction
0.937 0.063 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.935 0.065 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.934 0.066 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.932 0.068 0.000
S60-S69 Injuries to the wrist and hand
0.932 0.068 0.000
A30-A49 Other bacterial diseases
0.931 0.069 0.000
J30-J39 Other diseases of upper respiratory tract
0.926 0.074 0.000
E70-E90 Metabolic disorders
0.923 0.077 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.918 0.082 0.000
I20.9 Angina pectoris, unspecified
0.918 0.082 0.000
I42 Cardiomyopathy
0.915 0.085 0.000
Chapter XXI Factors influencing health status and contact with health services
0.913 0.087 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.911 0.089 0.000
E11.9 Without complications
0.910 0.090 0.000
J18 Pneumonia, organism unspecified
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.908 0.092 0.000
I49 Other cardiac arrhythmias
0.908 0.092 0.000
I25.2 Old myocardial infarction
0.906 0.094 0.000
I35.1 Aortic (valve) insufficiency
0.896 0.104 0.000
I24.8 Other forms of acute ischaemic heart disease
0.894 0.106 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.893 0.107 0.000
I08 Multiple valve diseases
0.893 0.107 0.000
J18.1 Lobar pneumonia, unspecified
0.892 0.108 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.880 0.120 0.000
O16 Unspecified maternal hypertension
0.880 0.120 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.876 0.124 0.000
S61 Open wound of wrist and hand
0.876 0.124 0.000
J90-J94 Other diseases of pleura
0.875 0.125 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.871 0.129 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.870 0.130 0.000
I44 Atrioventricular and left bundle-branch block
0.867 0.133 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.865 0.135 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.863 0.137 0.000
F10.0 Acute intoxication
0.861 0.139 0.000
M20-M25 Other joint disorders
0.856 0.144 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.854 0.146 0.000
E78.5 Hyperlipidaemia, unspecified
0.853 0.147 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.851 0.149 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.848 0.152 0.000
I45 Other conduction disorders
0.848 0.152 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.847 0.153 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.847 0.153 0.000
J32 Chronic sinusitis
0.845 0.155 0.000
Chapter XX External causes of morbidity and mortality
0.845 0.155 0.000
I20.0 Unstable angina
0.844 0.156 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.841 0.159 0.000
F10.1 Harmful use
0.841 0.159 0.000
I35.9 Aortic valve disorder, unspecified
0.840 0.160 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.837 0.163 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.837 0.163 0.000
I38 Endocarditis, valve unspecified
0.836 0.164 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.836 0.164 0.000
S00-S09 Injuries to the head
0.834 0.166 0.000
O80-O84 Delivery
0.834 0.166 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.833 0.167 0.000
H65-H75 Diseases of middle ear and mastoid
0.833 0.167 0.000
A49 Bacterial infection of unspecified site
0.831 0.169 0.000
S70-S79 Injuries to the hip and thigh
0.831 0.169 0.000
B35-B49 Mycoses
0.825 0.175 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.819 0.181 0.000
Z93 Artificial opening status
0.819 0.181 0.000
G40-G47 Episodic and paroxysmal disorders
0.814 0.186 0.000
Z95.2 Presence of prosthetic heart valve
0.814 0.186 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.814 0.186 0.000
I51 Complications and ill-defined descriptions of heart disease
0.813 0.187 0.000
G62 Other polyneuropathies
0.811 0.189 0.000
E11.4 With neurological complications
0.808 0.192 0.000
I35.0 Aortic (valve) stenosis
0.805 0.195 0.000
J60-J70 Lung diseases due to external agents
0.804 0.196 0.000
S80-S89 Injuries to the knee and lower leg
0.803 0.197 0.000
M05-M14 Inflammatory polyarthropathies
0.803 0.197 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.803 0.197 0.000
M45-M49 Spondylopathies
0.803 0.197 0.000
A41 Other septicaemia
0.801 0.199 0.000
I49.9 Cardiac arrhythmia, unspecified
0.798 0.202 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.798 0.202 0.000
I49.8 Other specified cardiac arrhythmias
0.797 0.203 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.795 0.205 0.000
M24 Other specific joint derangements
0.795 0.205 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.788 0.212 0.000
E13 Other specified diabetes mellitus
0.786 0.213 0.000
E10 Insulin-dependent diabetes mellitus
0.786 0.214 0.000
E87.6 Hypokalaemia
0.785 0.215 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.782 0.218 0.000
E65-E68 Obesity and other hyperalimentation
0.782 0.218 0.000
O36 Maternal care for other known or suspected foetal problems
0.781 0.219 0.000
I42.9 Cardiomyopathy, unspecified
0.781 0.219 0.000
S50-S59 Injuries to the elbow and forearm
0.779 0.221 0.000
Z95.1 Presence of aortocoronary bypass graft
0.779 0.221 0.000
G90-G99 Other disorders of the nervous system
0.778 0.222 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.777 0.223 0.000
I21 Acute myocardial infarction
0.776 0.224 0.000
Z93.2 Ileostomy status
0.776 0.224 0.000
I25.5 Ischaemic cardiomyopathy
0.771 0.229 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.770 0.230 0.000
H65 Nonsuppurative otitis media
0.768 0.232 0.000
E87.2 Acidosis
0.766 0.234 0.000
G70-G73 Diseases of myoneural junction and muscle
0.764 0.236 0.000
S20-S29 Injuries to the thorax
0.763 0.237 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.762 0.238 0.000
I33 Acute and subacute endocarditis
0.761 0.239 0.000
S61.8 Open wound of other parts of wrist and hand
0.761 0.239 0.000
M47 Spondylosis
0.760 0.240 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.759 0.241 0.000
O20 Haemorrhage in early pregnancy
0.758 0.242 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.757 0.243 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.757 0.243 0.000
M86-M90 Other osteopathies
0.757 0.243 0.000
S61.0 Open wound of finger(s) without damage to nail
0.756 0.244 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.756 0.244 0.000
I42.0 Dilated cardiomyopathy
0.756 0.244 0.000
Z95.0 Presence of cardiac pacemaker
0.755 0.245 0.000
A49.0 Staphylococcal infection, unspecified
0.753 0.247 0.000
H90-H95 Other disorders of ear
0.753 0.247 0.000
J35 Chronic diseases of tonsils and adenoids
0.752 0.248 0.000
M24.1 Other articular cartilage disorders
0.751 0.249 0.000
T39.1 4-Aminophenol derivatives
0.750 0.250 0.000
G35 Multiple sclerosis
0.750 0.250 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.748 0.252 0.000
I60-I69 Cerebrovascular diseases
0.747 0.253 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.746 0.253 0.000
S67 Crushing injury of wrist and hand
0.745 0.255 0.000
G51 Facial nerve disorders
0.742 0.257 0.000
T79-T79 Certain early complications of trauma
0.742 0.258 0.000
I47 Paroxysmal tachycardia
0.741 0.259 0.000
M47.8 Other spondylosis
0.741 0.259 0.000
I46 Cardiac arrest
0.739 0.261 0.000
F30-F39 Mood [affective] disorders
0.738 0.262 0.000
I31 Other diseases of pericardium
0.738 0.262 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.738 0.262 0.000
A80-A89 Viral infections of the central nervous system
0.737 0.263 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.737 0.263 0.000
J93 Pneumothorax
0.736 0.264 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.735 0.265 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.734 0.266 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.733 0.267 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.732 0.267 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.732 0.268 0.000
Z57 Occupational exposure to risk-factors
0.730 0.270 0.000
E11.5 With peripheral circulatory complications
0.730 0.270 0.000
E50-E64 Other nutritional deficiencies
0.730 0.270 0.000
I45.1 Other and unspecified right bundle-branch block
0.730 0.270 0.000
M25 Other joint disorders, not elsewhere classified
0.730 0.270 0.000
O82 Single delivery by Caesarean section
0.729 0.271 0.000
G62.9 Polyneuropathy, unspecified
0.729 0.271 0.000
F10.2 Dependence syndrome
0.728 0.272 0.000
I44.7 Left bundle-branch block, unspecified
0.728 0.272 0.000
M91-M94 Chondropathies
0.727 0.273 0.000
Z88.0 Personal history of allergy to penicillin
0.726 0.274 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.725 0.275 0.000
J34 Other disorders of nose and nasal sinuses
0.725 0.275 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.723 0.277 0.000
J18.0 Bronchopneumonia, unspecified
0.723 0.277 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.720 0.280 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.720 0.280 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.718 0.282 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.718 0.282 0.000
G37 Other demyelinating diseases of central nervous system
0.718 0.282 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I50.9 Heart failure, unspecified
0.717 0.283 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.716 0.284 0.000
F10.3 Withdrawal state
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
M70-M79 Other soft tissue disorders
0.715 0.285 0.000
S06 Intracranial injury
0.715 0.285 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.715 0.285 0.000
T51 Toxic effect of alcohol
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
Z95.4 Presence of other heart-valve replacement
0.712 0.287 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.712 0.288 0.000
I25.1 Atherosclerotic heart disease
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.711 0.289 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.711 0.289 0.000
E11.3 With ophthalmic complications
0.711 0.289 0.000
E40-E46 Malnutrition
0.709 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
I08.0 Disorders of both mitral and aortic valves
0.708 0.292 0.000
T66-T78 Other and unspecified effects of external causes
0.707 0.292 0.000
O36.8 Maternal care for other specified foetal problems
0.707 0.293 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.707 0.293 0.000
J32.9 Chronic sinusitis, unspecified
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
M47.82 Other spondylosis (Cervical region)
0.705 0.295 0.000
I24.1 Dressler's syndrome
0.705 0.295 0.000
J90 Pleural effusion, not elsewhere classified
0.703 0.297 0.000
G60 Hereditary and idiopathic neuropathy
0.703 0.297 0.000
H60-H62 Diseases of external ear
0.701 0.299 0.000
J31.0 Chronic rhinitis
0.701 0.299 0.000
S81 Open wound of lower leg
0.700 0.300 0.000
B37 Candidiasis
0.700 0.300 0.000
I51.8 Other ill-defined heart diseases
0.699 0.301 0.000
S80 Superficial injury of lower leg
0.699 0.301 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.699 0.301 0.000
M65-M68 Disorders of synovium and tendon
0.699 0.301 0.000
E12 Malnutrition-related diabetes mellitus
0.699 0.301 0.000
E14 Unspecified diabetes mellitus
0.697 0.303 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.697 0.303 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.697 0.303 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.697 0.303 0.000
I35.8 Other aortic valve disorders
0.696 0.304 0.000
O47 False labour
0.696 0.304 0.000
G30-G32 Other degenerative diseases of the nervous system
0.696 0.304 0.000
I05 Rheumatic mitral valve diseases
0.696 0.304 0.000
S60 Superficial injury of wrist and hand
0.695 0.305 0.000
O15 Eclampsia
0.693 0.306 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.693 0.306 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.693 0.306 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.693 0.306 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.693 0.307 0.000
I49.3 Ventricular premature depolarisation
0.691 0.309 0.000
G50 Disorders of trigeminal nerve
0.690 0.310 0.000
I25.6 Silent myocardial ischaemia
0.690 0.310 0.000
I25.4 Coronary artery aneurysm
0.690 0.310 0.000
I25.3 Aneurysm of heart
0.690 0.310 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.687 0.313 0.000
F80-F89 Disorders of psychological development
0.687 0.313 0.000
F70-F79 Mental retardation
0.687 0.313 0.000
F60-F69 Disorders of adult personality and behaviour
0.687 0.313 0.000
E86 Volume depletion
0.686 0.314 0.000
H65.3 Chronic mucoid otitis media
0.686 0.314 0.000
I44.1 Atrioventricular block, second degree
0.686 0.314 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.685 0.314 0.000
I44.3 Other and unspecified atrioventricular block
0.685 0.315 0.000
M10 Gout
0.683 0.317 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.683 0.317 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.682 0.318 0.000
M40-M43 Deforming dorsopathies
0.682 0.318 0.000
E11.8 With unspecified complications
0.682 0.318 0.000
E11.7 With multiple complications
0.682 0.318 0.000
E11.6 With other specified complications
0.682 0.318 0.000
E11.1 With ketoacidosis
0.682 0.318 0.000
E11.0 With coma
0.682 0.318 0.000
Q50-Q56 Congenital malformations of genital organs
0.681 0.318 0.000
I07 Rheumatic tricuspid valve diseases
0.680 0.320 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.680 0.320 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.679 0.320 0.000
O44 Placenta praevia
0.679 0.321 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.679 0.321 0.000
I42.2 Other hypertrophic cardiomyopathy
0.678 0.321 0.000
E20-E35 Disorders of other endocrine glands
0.677 0.323 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.677 0.323 0.000
J92 Pleural plaque
0.676 0.324 0.000
S70 Superficial injury of hip and thigh
0.676 0.324 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.676 0.324 0.000
J17 Pneumonia in diseases classified elsewhere
0.676 0.324 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.676 0.324 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.676 0.324 0.000
J12 Viral pneumonia, not elsewhere classified
0.676 0.324 0.000
J11 Influenza, virus not identified
0.676 0.324 0.000
J10 Influenza due to identified influenza virus
0.676 0.324 0.000
J14 Pneumonia due to Haemophilus influenzae
0.676 0.324 0.000
J09 Influenza due to certain identified influenza virus
0.676 0.324 0.000
M60-M63 Disorders of muscles
0.675 0.324 0.000
G51.0 Bell's palsy
0.675 0.325 0.000
I09 Other rheumatic heart diseases
0.674 0.326 0.000
I06 Rheumatic aortic valve diseases
0.674 0.326 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.674 0.326 0.000
J40-J47 Chronic lower respiratory diseases
0.674 0.326 0.000
J32.2 Chronic ethmoidal sinusitis
0.673 0.326 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.673 0.326 0.000
I22.8 Subsequent myocardial infarction of other sites
0.672 0.328 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.672 0.328 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.671 0.329 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.671 0.329 0.000
M22 Disorders of patella
0.671 0.329 0.000
J94 Other pleural conditions
0.670 0.330 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.670 0.330 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.670 0.330 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.670 0.330 0.000
E11.2 With renal complications
0.670 0.330 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.330 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.330 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.330 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.670 0.330 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.670 0.330 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.330 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.330 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
T36 Poisoning by systemic antibiotics
0.670 0.330 0.000
S90-S99 Injuries to the ankle and foot
0.669 0.330 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.668 0.331 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.668 0.332 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.668 0.332 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.668 0.332 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.668 0.332 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.668 0.332 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.668 0.332 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.668 0.332 0.000
F11 Mental and behavioural disorders due to use of opioids
0.668 0.332 0.000
S69 Other and unspecified injuries of wrist and hand
0.668 0.332 0.000
S65 Injury of blood vessels at wrist and hand level
0.668 0.332 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.668 0.332 0.000
A48 Other bacterial diseases, not elsewhere classified
0.667 0.333 0.000
A44 Bartonellosis
0.667 0.333 0.000
A43 Nocardiosis
0.667 0.333 0.000
A42 Actinomycosis
0.667 0.333 0.000
A40 Streptococcal septicaemia
0.667 0.333 0.000
A39 Meningococcal infection
0.667 0.333 0.000
A37 Whooping cough
0.667 0.333 0.000
A36 Diphtheria
0.667 0.333 0.000
A32 Listeriosis
0.667 0.333 0.000
A31 Infection due to other mycobacteria
0.667 0.333 0.000
A30 Leprosy [Hansen's disease]
0.667 0.333 0.000
A46 Erysipelas
0.667 0.333 0.000
A38 Scarlet fever
0.667 0.333 0.000
A35 Other tetanus
0.667 0.333 0.000
A34 Obstetrical tetanus
0.667 0.333 0.000
A33 Tetanus neonatorum
0.667 0.333 0.000
B25-B34 Other viral diseases
0.666 0.333 0.000
S71 Open wound of hip and thigh
0.666 0.334 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.665 0.335 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
J32.8 Other chronic sinusitis
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.336 0.000
G93 Other disorders of brain
0.664 0.336 0.000
J37 Chronic laryngitis and laryngotracheitis
0.664 0.336 0.000
J32.0 Chronic maxillary sinusitis
0.663 0.337 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.663 0.337 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.663 0.337 0.000
S01 Open wound of head
0.663 0.337 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.662 0.338 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.662 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.338 0.000
E85 Amyloidosis
0.662 0.338 0.000
E84 Cystic fibrosis
0.662 0.338 0.000
E79 Disorders of purine and pyrimidine metabolism
0.662 0.338 0.000
E77 Disorders of glycoprotein metabolism
0.662 0.338 0.000
E76 Disorders of glycosaminoglycan metabolism
0.662 0.338 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.662 0.338 0.000
E74 Other disorders of carbohydrate metabolism
0.662 0.338 0.000
E73 Lactose intolerance
0.662 0.338 0.000
E72 Other disorders of amino-acid metabolism
0.662 0.338 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.662 0.338 0.000
E70 Disorders of aromatic amino-acid metabolism
0.662 0.338 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.662 0.338 0.000
F99-F99 Unspecified mental disorder
0.662 0.338 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.661 0.338 0.000
M21 Other acquired deformities of limbs
0.661 0.339 0.000
Z98 Other postsurgical states
0.660 0.340 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.660 0.340 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.660 0.340 0.000
A00-A09 Intestinal infectious diseases
0.659 0.341 0.000
I44.2 Atrioventricular block, complete
0.659 0.341 0.000
I20.1 Angina pectoris with documented spasm
0.659 0.341 0.000
F10.9 Unspecified mental and behavioural disorder
0.658 0.341 0.000
F10.8 Other mental and behavioural disorders
0.658 0.341 0.000
F10.7 Residual and late-onset psychotic disorder
0.658 0.341 0.000
F10.6 Amnesic syndrome
0.658 0.341 0.000
F10.5 Psychotic disorder
0.658 0.341 0.000
F10.4 Withdrawal state with delirium
0.658 0.341 0.000
Z94 Transplanted organ and tissue status
0.658 0.342 0.000
S64 Injury of nerves at wrist and hand level
0.658 0.342 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.658 0.342 0.000
T39.0 Salicylates
0.657 0.343 0.000
I42.8 Other cardiomyopathies
0.656 0.344 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.656 0.344 0.000
I42.6 Alcoholic cardiomyopathy
0.656 0.344 0.000
I42.5 Other restrictive cardiomyopathy
0.656 0.344 0.000
I42.4 Endocardial fibroelastosis
0.656 0.344 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.656 0.344 0.000
Z89 Acquired absence of limb
0.654 0.346 0.000
G64 Other disorders of peripheral nervous system
0.653 0.346 0.000
O82.0 Delivery by elective Caesarean section
0.653 0.347 0.000
M35 Other systemic involvement of connective tissue
0.652 0.348 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.652 0.348 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.652 0.348 0.000
J18.8 Other pneumonia, organism unspecified
0.652 0.348 0.000
J18.2 Hypostatic pneumonia, unspecified
0.652 0.348 0.000
E13.9 Without complications
0.652 0.348 0.000
O23 Infections of genito-urinary tract in pregnancy
0.652 0.348 0.000
J95-J99 Other diseases of the respiratory system
0.652 0.348 0.000
I49.4 Other and unspecified premature depolarisation
0.651 0.349 0.000
I49.2 Junctional premature depolarisation
0.651 0.349 0.000
I49.1 Atrial premature depolarisation
0.651 0.349 0.000
E87.0 Hyperosmolality and hypernatraemia
0.651 0.349 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.651 0.349 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.649 0.351 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.649 0.351 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.649 0.351 0.000
S62 Fracture at wrist and hand level
0.649 0.351 0.000
G63.2 Diabetic polyneuropathy
0.647 0.353 0.000
G54 Nerve root and plexus disorders
0.646 0.354 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.646 0.354 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.645 0.355 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.645 0.355 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.645 0.355 0.000
M25.5 Pain in joint
0.644 0.356 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.644 0.356 0.000
J39 Other diseases of upper respiratory tract
0.644 0.356 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.641 0.359 0.000
I08.9 Multiple valve disease, unspecified
0.640 0.360 0.000
I08.8 Other multiple valve diseases
0.640 0.360 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.640 0.360 0.000
Z36 Antenatal screening
0.639 0.361 0.000
Z97 Presence of other devices
0.639 0.361 0.000
H73 Other disorders of tympanic membrane
0.639 0.361 0.000
H72 Perforation of tympanic membrane
0.638 0.362 0.000
I49.5 Sick sinus syndrome
0.638 0.362 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.637 0.363 0.000
T63 Toxic effect of contact with venomous animals
0.636 0.363 0.000
J44 Other chronic obstructive pulmonary disease
0.636 0.364 0.000
E66 Obesity
0.634 0.366 0.000
J30 Vasomotor and allergic rhinitis
0.633 0.367 0.000
S51 Open wound of forearm
0.633 0.367 0.000
I21.9 Acute myocardial infarction, unspecified
0.633 0.367 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.632 0.368 0.000
J93.9 Pneumothorax, unspecified
0.631 0.369 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.630 0.370 0.000
G20-G26 Extrapyramidal and movement disorders
0.629 0.371 0.000
M87 Osteonecrosis
0.629 0.371 0.000
G36 Other acute disseminated demyelination
0.628 0.372 0.000
Q60-Q64 Congenital malformations of the urinary system
0.628 0.372 0.000
S61.7 Multiple open wounds of wrist and hand
0.628 0.372 0.000
I45.9 Conduction disorder, unspecified
0.628 0.372 0.000
O36.5 Maternal care for poor foetal growth
0.626 0.374 0.000
Z63 Other problems related to primary support group, including family circumstances
0.626 0.374 0.000
J84 Other interstitial pulmonary diseases
0.626 0.374 0.000
M06 Other rheumatoid arthritis
0.626 0.374 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.625 0.375 0.000
E88 Other metabolic disorders
0.625 0.375 0.000
E78.8 Other disorders of lipoprotein metabolism
0.624 0.376 0.000
E78.6 Lipoprotein deficiency
0.624 0.376 0.000
E78.4 Other hyperlipidaemia
0.624 0.376 0.000
E78.3 Hyperchylomicronaemia
0.624 0.376 0.000
E78.2 Mixed hyperlipidaemia
0.624 0.376 0.000
E78.1 Pure hyperglyceridaemia
0.624 0.376 0.000
Z84 Family history of other conditions
0.624 0.376 0.000
Z81 Family history of mental and behavioural disorders
0.624 0.376 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.623 0.377 0.000
Z93.5 Cystostomy status
0.623 0.377 0.000
G58 Other mononeuropathies
0.623 0.377 0.000
T51.0 Ethanol
0.623 0.377 0.000
Y42.7 Androgens and anabolic congeners
0.622 0.378 0.000
H91 Other hearing loss
0.622 0.378 0.000
Y52 Agents primarily affecting the cardiovascular system
0.622 0.378 0.000
I44.6 Other and unspecified fascicular block
0.621 0.378 0.000
I44.5 Left posterior fascicular block
0.621 0.378 0.000
I44.4 Left anterior fascicular block
0.621 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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