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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12201940
log Bayes Factor = 14.3443
Chromosome 6   position 5,859,679  (GRCh37) Explore rs12201940 on Ensembl!
Variant rs12201940 is part of Cluster X0062

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.993 0.007 0.000
B95-B98 Bacterial, viral and other infectious agents
0.993 0.007 0.000
S00-S09 Injuries to the head
0.993 0.007 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.991 0.009 0.000
A30-A49 Other bacterial diseases
0.991 0.009 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.988 0.012 0.000
Chapter XIV Diseases of the genitourinary system
0.987 0.013 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
K83 Other diseases of biliary tract
0.980 0.020 0.000
N30-N39 Other diseases of urinary system
0.978 0.022 0.000
N32 Other disorders of bladder
0.974 0.026 0.000
A41 Other septicaemia
0.973 0.027 0.000
K80 Cholelithiasis
0.964 0.036 0.000
K50-K52 Noninfective enteritis and colitis
0.963 0.037 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.963 0.037 0.000
M80-M85 Disorders of bone density and structure
0.962 0.038 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.949 0.051 0.000
M25 Other joint disorders, not elsewhere classified
0.944 0.056 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.944 0.056 0.000
S06 Intracranial injury
0.943 0.057 0.000
K50 Crohn's disease [regional enteritis]
0.937 0.063 0.000
M24 Other specific joint derangements
0.937 0.063 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.936 0.064 0.000
K83.8 Other specified diseases of biliary tract
0.932 0.068 0.000
N17-N19 Renal failure
0.932 0.068 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.928 0.072 0.000
S01 Open wound of head
0.920 0.080 0.000
Chapter II Neoplasms
0.920 0.080 0.000
N32.3 Diverticulum of bladder
0.918 0.082 0.000
M84 Disorders of continuity of bone
0.911 0.089 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.909 0.091 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.907 0.093 0.000
D10-D36 Benign neoplasms
0.902 0.098 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.902 0.098 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.900 0.100 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.899 0.101 0.000
A41.8 Other specified septicaemia
0.897 0.103 0.000
K85 Acute pancreatitis
0.896 0.104 0.000
N25-N29 Other disorders of kidney and ureter
0.895 0.105 0.000
M70-M79 Other soft tissue disorders
0.893 0.107 0.000
M25.7 Osteophyte
0.890 0.110 0.000
G40-G47 Episodic and paroxysmal disorders
0.889 0.111 0.000
K50.9 Crohn's disease, unspecified
0.884 0.116 0.000
R26 Abnormalities of gait and mobility
0.882 0.118 0.000
A49 Bacterial infection of unspecified site
0.882 0.118 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.880 0.120 0.000
N18 Chronic renal failure
0.880 0.120 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.878 0.122 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.878 0.122 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.878 0.122 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.878 0.122 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.876 0.124 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.873 0.127 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.871 0.129 0.000
R00 Abnormalities of heart beat
0.868 0.132 0.000
B35-B49 Mycoses
0.867 0.133 0.000
K70-K77 Diseases of liver
0.866 0.134 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
R05 Cough
0.862 0.138 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.862 0.138 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.861 0.139 0.000
G70-G73 Diseases of myoneural junction and muscle
0.860 0.140 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.859 0.141 0.000
Chapter XX External causes of morbidity and mortality
0.854 0.146 0.000
K65-K67 Diseases of peritoneum
0.853 0.147 0.000
M86-M90 Other osteopathies
0.853 0.147 0.000
N32.8 Other specified disorders of bladder
0.853 0.147 0.000
S06.5 Traumatic subdural haemorrhage
0.850 0.150 0.000
N20-N23 Urolithiasis
0.850 0.150 0.000
R29.6 Tendency to fall, not elsewhere classified
0.850 0.150 0.000
N32.0 Bladder-neck obstruction
0.847 0.153 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.846 0.154 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.845 0.155 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.841 0.159 0.000
K81 Cholecystitis
0.841 0.159 0.000
K51 Ulcerative colitis
0.840 0.160 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.840 0.160 0.000
K83.0 Cholangitis
0.839 0.161 0.000
G47 Sleep disorders
0.838 0.162 0.000
B15-B19 Viral hepatitis
0.837 0.163 0.000
D17 Benign lipomatous neoplasm
0.837 0.163 0.000
N32.1 Vesicointestinal fistula
0.836 0.164 0.000
S40-S49 Injuries to the shoulder and upper arm
0.834 0.166 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.831 0.169 0.000
K83.1 Obstruction of bile duct
0.830 0.170 0.000
T90 Sequelae of injuries of head
0.829 0.171 0.000
K90-K93 Other diseases of the digestive system
0.824 0.176 0.000
D36 Benign neoplasm of other and unspecified sites
0.823 0.177 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.823 0.177 0.000
M05-M14 Inflammatory polyarthropathies
0.822 0.178 0.000
D12.3 Transverse colon
0.822 0.178 0.000
D12.0 Caecum
0.822 0.178 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.821 0.179 0.000
S05 Injury of eye and orbit
0.821 0.179 0.000
G30-G32 Other degenerative diseases of the nervous system
0.819 0.181 0.000
M24.0 Loose body in joint
0.819 0.181 0.000
C64-C68 Malignant neoplasms of urinary tract
0.818 0.182 0.000
N32.9 Bladder disorder, unspecified
0.817 0.183 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.812 0.188 0.000
G43 Migraine
0.812 0.188 0.000
M25.76 Osteophyte (Lower leg)
0.811 0.189 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.811 0.189 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.810 0.190 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.807 0.193 0.000
S10-S19 Injuries to the neck
0.807 0.193 0.000
S00 Superficial injury of head
0.804 0.196 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.803 0.197 0.000
S50-S59 Injuries to the elbow and forearm
0.803 0.197 0.000
N17 Acute renal failure
0.802 0.198 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.802 0.198 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.801 0.199 0.000
M34 Systemic sclerosis
0.800 0.200 0.000
R21 Rash and other nonspecific skin eruption
0.798 0.202 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.798 0.202 0.000
N18.9 Chronic renal failure, unspecified
0.796 0.204 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
T86 Failure and rejection of transplanted organs and tissues
0.794 0.206 0.000
M23 Internal derangement of knee
0.793 0.207 0.000
M84.0 Malunion of fracture
0.793 0.207 0.000
K35-K38 Diseases of appendix
0.793 0.207 0.000
G47.3 Sleep apnoea
0.792 0.208 0.000
Chapter V Mental and behavioural disorders
0.791 0.209 0.000
G20-G26 Extrapyramidal and movement disorders
0.790 0.210 0.000
R25 Abnormal involuntary movements
0.787 0.213 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.786 0.214 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.786 0.214 0.000
M81 Osteoporosis without pathological fracture
0.786 0.214 0.000
K85.1 Biliary acute pancreatitis
0.786 0.214 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.783 0.217 0.000
T98 Sequelae of other and unspecified effects of external causes
0.783 0.217 0.000
K80.4 Calculus of bile duct with cholecystitis
0.781 0.219 0.000
R00.2 Palpitations
0.781 0.219 0.000
D60-D64 Aplastic and other anaemias
0.777 0.223 0.000
K90 Intestinal malabsorption
0.777 0.223 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.776 0.224 0.000
G43.9 Migraine, unspecified
0.775 0.225 0.000
S01.3 Open wound of ear
0.775 0.225 0.000
G90-G99 Other disorders of the nervous system
0.774 0.226 0.000
D50-D53 Nutritional anaemias
0.773 0.227 0.000
R03.1 Nonspecific low blood-pressure reading
0.773 0.227 0.000
T92 Sequelae of injuries of upper limb
0.773 0.227 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.773 0.227 0.000
D22 Melanocytic naevi
0.772 0.228 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.770 0.230 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.768 0.232 0.000
M24.5 Contracture of joint
0.767 0.233 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.765 0.235 0.000
K50.0 Crohn's disease of small intestine
0.765 0.235 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.765 0.235 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.765 0.235 0.000
S06.3 Focal brain injury
0.764 0.236 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.764 0.236 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.764 0.236 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.763 0.237 0.000
S01.2 Open wound of nose
0.763 0.237 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.762 0.238 0.000
N23 Unspecified renal colic
0.762 0.238 0.000
M21 Other acquired deformities of limbs
0.761 0.239 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.761 0.239 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.760 0.240 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
K50.1 Crohn's disease of large intestine
0.757 0.243 0.000
M79.8 Other specified soft tissue disorders
0.757 0.243 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.757 0.243 0.000
S09 Other and unspecified injuries of head
0.756 0.244 0.000
K70 Alcoholic liver disease
0.754 0.246 0.000
O60-O75 Complications of labour and delivery
0.754 0.246 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.754 0.246 0.000
G71 Primary disorders of muscles
0.751 0.249 0.000
Chapter VII Diseases of the eye and adnexa
0.749 0.251 0.000
M25.4 Effusion of joint
0.749 0.251 0.000
M23.3 Other meniscus derangements
0.748 0.252 0.000
R20 Disturbances of skin sensation
0.747 0.253 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.747 0.253 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.747 0.253 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.745 0.255 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.745 0.255 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.743 0.257 0.000
M00-M03 Infectious arthropathies
0.742 0.258 0.000
T91 Sequelae of injuries of neck and trunk
0.741 0.259 0.000
M91-M94 Chondropathies
0.740 0.260 0.000
T79-T79 Certain early complications of trauma
0.738 0.262 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.738 0.262 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.738 0.262 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.738 0.262 0.000
N99-N99 Other disorders of the genitourinary system
0.736 0.264 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.735 0.265 0.000
M24.1 Other articular cartilage disorders
0.735 0.265 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.734 0.266 0.000
M25.77 Osteophyte (Ankle and foot)
0.734 0.266 0.000
M22 Disorders of patella
0.731 0.269 0.000
N30 Cystitis
0.730 0.270 0.000
O63 Long labour
0.729 0.271 0.000
T87 Complications peculiar to reattachment and amputation
0.729 0.271 0.000
K50.8 Other Crohn's disease
0.728 0.272 0.000
M71 Other bursopathies
0.727 0.273 0.000
D34 Benign neoplasm of thyroid gland
0.727 0.273 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.727 0.273 0.000
K85.9 Acute pancreatitis, unspecified
0.726 0.274 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.726 0.274 0.000
R04 Haemorrhage from respiratory passages
0.725 0.275 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.725 0.275 0.000
S06.4 Epidural haemorrhage
0.724 0.276 0.000
S06.8 Other intracranial injuries
0.723 0.276 0.000
R41.3 Other amnesia
0.724 0.276 0.000
C51-C58 Malignant neoplasms of female genital organs
0.723 0.277 0.000
Q60-Q64 Congenital malformations of the urinary system
0.723 0.277 0.000
D12.7 Rectosigmoid junction
0.722 0.278 0.000
N18.2 Chronic kidney disease, stage 2
0.722 0.278 0.000
K66 Other disorders of peritoneum
0.722 0.278 0.000
N18.5 Chronic kidney disease, stage 5
0.721 0.279 0.000
S01.8 Open wound of other parts of head
0.721 0.279 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.720 0.279 0.000
B18 Chronic viral hepatitis
0.720 0.280 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.720 0.280 0.000
S60-S69 Injuries to the wrist and hand
0.720 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.720 0.280 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.718 0.282 0.000
S01.5 Open wound of lip and oral cavity
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E00-E07 Disorders of thyroid gland
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
D51 Vitamin B12 deficiency anaemia
0.716 0.284 0.000
M82 Osteoporosis in diseases classified elsewhere
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
S01.9 Open wound of head, part unspecified
0.716 0.284 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.284 0.000
M79.5 Residual foreign body in soft tissue
0.715 0.285 0.000
A49.0 Staphylococcal infection, unspecified
0.715 0.285 0.000
K81.0 Acute cholecystitis
0.715 0.285 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.715 0.285 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.714 0.286 0.000
M10 Gout
0.714 0.286 0.000
K82 Other diseases of gallbladder
0.713 0.287 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.713 0.287 0.000
M84.4 Pathological fracture, not elsewhere classified
0.712 0.288 0.000
N10-N16 Renal tubulo-interstitial diseases
0.712 0.288 0.000
S08 Traumatic amputation of part of head
0.712 0.288 0.000
S07 Crushing injury of head
0.712 0.288 0.000
S04 Injury of cranial nerves
0.712 0.288 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.712 0.288 0.000
B37 Candidiasis
0.712 0.288 0.000
A49.1 Streptococcal infection, unspecified
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
A49.8 Other bacterial infections of unspecified site
0.711 0.289 0.000
G35 Multiple sclerosis
0.710 0.290 0.000
A48 Other bacterial diseases, not elsewhere classified
0.710 0.290 0.000
A44 Bartonellosis
0.710 0.290 0.000
A43 Nocardiosis
0.710 0.290 0.000
A42 Actinomycosis
0.710 0.290 0.000
A40 Streptococcal septicaemia
0.710 0.290 0.000
A39 Meningococcal infection
0.710 0.290 0.000
A37 Whooping cough
0.710 0.290 0.000
A36 Diphtheria
0.710 0.290 0.000
A32 Listeriosis
0.710 0.290 0.000
A31 Infection due to other mycobacteria
0.710 0.290 0.000
A30 Leprosy [Hansen's disease]
0.710 0.290 0.000
A46 Erysipelas
0.710 0.290 0.000
A38 Scarlet fever
0.710 0.290 0.000
A35 Other tetanus
0.710 0.290 0.000
A34 Obstetrical tetanus
0.710 0.290 0.000
A33 Tetanus neonatorum
0.710 0.290 0.000
D00-D09 In situ neoplasms
0.710 0.290 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.709 0.291 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.707 0.293 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.707 0.293 0.000
K90.0 Coeliac disease
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.704 0.296 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.703 0.296 0.000
B49 Unspecified mycosis
0.703 0.297 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.703 0.297 0.000
M85 Other disorders of bone density and structure
0.702 0.297 0.000
K83.9 Disease of biliary tract, unspecified
0.702 0.298 0.000
K83.5 Biliary cyst
0.702 0.298 0.000
K83.4 Spasm of sphincter of Oddi
0.702 0.298 0.000
K83.3 Fistula of bile duct
0.702 0.298 0.000
K83.2 Perforation of bile duct
0.702 0.298 0.000
R26.3 Immobility
0.702 0.298 0.000
M25.71 Osteophyte (Shoulder region)
0.702 0.298 0.000
N37 Urethral disorders in diseases classified elsewhere
0.701 0.299 0.000
N34 Urethritis and urethral syndrome
0.701 0.299 0.000
N33 Bladder disorders in diseases classified elsewhere
0.701 0.299 0.000
M80 Osteoporosis with pathological fracture
0.701 0.299 0.000
R27 Other lack of coordination
0.701 0.299 0.000
M89 Other disorders of bone
0.701 0.299 0.000
W20-W49 Exposure to inanimate mechanical forces
0.701 0.299 0.000
M24.02 Loose body in joint (Upper arm)
0.700 0.300 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.699 0.301 0.000
D12.6 Colon, unspecified
0.698 0.302 0.000
N32.4 Rupture of bladder, nontraumatic
0.698 0.302 0.000
N32.2 Vesical fistula, not elsewhere classified
0.698 0.302 0.000
M31 Other necrotising vasculopathies
0.698 0.302 0.000
S05.1 Contusion of eyeball and orbital tissues
0.698 0.302 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.698 0.302 0.000
A41.4 Septicaemia due to anaerobes
0.698 0.302 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.698 0.302 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.698 0.302 0.000
N26 Unspecified contracted kidney
0.697 0.303 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.697 0.303 0.000
A80-A89 Viral infections of the central nervous system
0.694 0.306 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.694 0.306 0.000
D30 Benign neoplasm of urinary organs
0.693 0.307 0.000
K81.1 Chronic cholecystitis
0.693 0.307 0.000
M24.2 Disorder of ligament
0.693 0.307 0.000
M45-M49 Spondylopathies
0.692 0.308 0.000
K74 Fibrosis and cirrhosis of liver
0.691 0.308 0.000
K80.3 Calculus of bile duct with cholangitis
0.691 0.308 0.000
K80.8 Other cholelithiasis
0.691 0.308 0.000
M20 Acquired deformities of fingers and toes
0.691 0.309 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.690 0.309 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.690 0.310 0.000
N28.8 Other specified disorders of kidney and ureter
0.690 0.310 0.000
O63.1 Prolonged second stage (of labour)
0.690 0.310 0.000
M83 Adult osteomalacia
0.690 0.310 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.688 0.312 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.688 0.312 0.000
C50-C50 Malignant neoplasm of breast
0.687 0.313 0.000
A00-A09 Intestinal infectious diseases
0.687 0.313 0.000
M81.4 Drug-induced osteoporosis
0.687 0.313 0.000
R00.0 Tachycardia, unspecified
0.686 0.314 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.686 0.314 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.681 0.319 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.681 0.319 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.681 0.319 0.000
R29.4 Clicking hip
0.680 0.320 0.000
R29.3 Abnormal posture
0.680 0.320 0.000
R29.2 Abnormal reflex
0.680 0.320 0.000
R29.1 Meningismus
0.680 0.320 0.000
R29.0 Tetany
0.680 0.320 0.000
W00-W19 Falls
0.679 0.321 0.000
S06.2 Diffuse brain injury
0.678 0.322 0.000
R41.0 Disorientation, unspecified
0.678 0.322 0.000
K37 Unspecified appendicitis
0.678 0.322 0.000
M25.9 Joint disorder, unspecified
0.677 0.323 0.000
M25.3 Other instability of joint
0.677 0.323 0.000
M25.2 Flail joint
0.677 0.323 0.000
M25.1 Fistula of joint
0.677 0.323 0.000
M25.0 Haemarthrosis
0.677 0.323 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
M79.6 Pain in limb
0.677 0.323 0.000
S06.9 Intracranial injury, unspecified
0.676 0.323 0.000
S06.7 Intracranial injury with prolonged coma
0.676 0.323 0.000
S06.1 Traumatic cerebral oedema
0.676 0.323 0.000
S06.0 Concussion
0.676 0.323 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.676 0.324 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.676 0.324 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.676 0.324 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.675 0.324 0.000
D16 Benign neoplasm of bone and articular cartilage
0.675 0.324 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.675 0.325 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.675 0.325 0.000
V80-V89 Other land transport accidents
0.674 0.326 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.674 0.326 0.000
Q50-Q56 Congenital malformations of genital organs
0.674 0.326 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.673 0.327 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.673 0.327 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.673 0.327 0.000
K51.2 Ulcerative (chronic) proctitis
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.672 0.327 0.000
D63.0 Anaemia in neoplastic disease
0.672 0.328 0.000
G37 Other demyelinating diseases of central nervous system
0.672 0.328 0.000
M24.9 Joint derangement, unspecified
0.672 0.328 0.000
M24.7 Protrusio acetabuli
0.672 0.328 0.000
M24.6 Ankylosis of joint
0.672 0.328 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.672 0.328 0.000
B25-B34 Other viral diseases
0.672 0.328 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.671 0.329 0.000
K90.9 Intestinal malabsorption, unspecified
0.670 0.330 0.000
D10 Benign neoplasm of mouth and pharynx
0.670 0.330 0.000
D12.9 Anus and anal canal
0.670 0.330 0.000
S70-S79 Injuries to the hip and thigh
0.669 0.330 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.668 0.331 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.668 0.332 0.000
R46 Symptoms and signs involving appearance and behaviour
0.667 0.333 0.000
O85-O92 Complications predominantly related to the puerperium
0.667 0.333 0.000
S01.1 Open wound of eyelid and periocular area
0.666 0.334 0.000
O80-O84 Delivery
0.666 0.334 0.000
S02 Fracture of skull and facial bones
0.666 0.334 0.000
G70 Myasthenia gravis and other myoneural disorders
0.666 0.334 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.666 0.334 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.666 0.334 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.666 0.334 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.666 0.334 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.666 0.334 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.666 0.334 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.666 0.334 0.000
S32 Fracture of lumbar spine and pelvis
0.665 0.335 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.665 0.335 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.664 0.336 0.000
N18.4 Chronic kidney disease, stage 4
0.664 0.336 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.663 0.337 0.000
T66-T78 Other and unspecified effects of external causes
0.663 0.337 0.000
M34.9 Systemic sclerosis, unspecified
0.663 0.337 0.000
H52 Disorders of refraction and accommodation
0.662 0.338 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.662 0.338 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.661 0.339 0.000
N17.9 Acute renal failure, unspecified
0.661 0.339 0.000
K65 Peritonitis
0.660 0.340 0.000
S01.7 Multiple open wounds of head
0.660 0.340 0.000
S01.4 Open wound of cheek and temporomandibular area
0.660 0.340 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.659 0.340 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.659 0.341 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.659 0.341 0.000
Chapter VIII Diseases of the ear and mastoid process
0.659 0.341 0.000
G96 Other disorders of central nervous system
0.658 0.342 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.658 0.342 0.000
R20.2 Paraesthesia of skin
0.658 0.342 0.000
S20-S29 Injuries to the thorax
0.656 0.344 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.656 0.344 0.000
N18.3 Chronic kidney disease, stage 3
0.656 0.344 0.000
M40-M43 Deforming dorsopathies
0.654 0.346 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.654 0.346 0.000
M84.9 Disorder of continuity of bone, unspecified
0.653 0.346 0.000
M84.8 Other disorders of continuity of bone
0.653 0.346 0.000
M84.3 Stress fracture, not elsewhere classified
0.653 0.346 0.000
M84.2 Delayed union of fracture
0.653 0.346 0.000
M24.07 Loose body in joint (Ankle and foot)
0.653 0.346 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.653 0.347 0.000
N17.0 Acute renal failure with tubular necrosis
0.653 0.347 0.000
M77 Other enthesopathies
0.652 0.348 0.000
D12.4 Descending colon
0.652 0.348 0.000
M84.06 Malunion of fracture (Lower leg)
0.651 0.349 0.000
N36 Other disorders of urethra
0.651 0.349 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.650 0.350 0.000
M25.78 Osteophyte (Other)
0.650 0.350 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.650 0.350 0.000
S64 Injury of nerves at wrist and hand level
0.649 0.351 0.000
M87 Osteonecrosis
0.649 0.351 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.648 0.352 0.000
N40-N51 Diseases of male genital organs
0.648 0.352 0.000
K51.5 Mucosal proctocolitis
0.647 0.353 0.000
W50-W64 Exposure to animate mechanical forces
0.647 0.353 0.000
D31 Benign neoplasm of eye and adnexa
0.647 0.353 0.000
D29 Benign neoplasm of male genital organs
0.647 0.353 0.000
D26 Other benign neoplasms of uterus
0.647 0.353 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.647 0.353 0.000
D19 Benign neoplasm of mesothelial tissue
0.647 0.353 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.647 0.353 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.646 0.353 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.646 0.353 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.646 0.354 0.000
M06 Other rheumatoid arthritis
0.646 0.354 0.000
M70.6 Trochanteric bursitis
0.646 0.354 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.645 0.355 0.000
N13 Obstructive and reflux uropathy
0.645 0.355 0.000
M24.54 Contracture of joint (Hand)
0.645 0.355 0.000
D55-D59 Haemolytic anaemias
0.644 0.356 0.000
B44 Aspergillosis
0.644 0.356 0.000
M79.7 Fibromyalgia
0.644 0.356 0.000
K72 Hepatic failure, not elsewhere classified
0.644 0.356 0.000
X50-X57 Overexertion, travel and privation
0.644 0.356 0.000
D11 Benign neoplasm of major salivary glands
0.644 0.356 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.644 0.356 0.000
C60-C63 Malignant neoplasms of male genital organs
0.643 0.357 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.643 0.357 0.000
K75 Other inflammatory liver diseases
0.643 0.357 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.643 0.357 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.642 0.358 0.000
K85.8 Other acute pancreatitis
0.642 0.358 0.000
K85.3 Drug-induced acute pancreatitis
0.642 0.358 0.000
K85.2 Alcohol-induced acute pancreatitis
0.642 0.358 0.000
K85.0 Idiopathic acute pancreatitis
0.642 0.358 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.642 0.358 0.000
N27 Small kidney of unknown cause
0.642 0.358 0.000
N25 Disorders resulting from impaired renal tubular function
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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