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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12686544
log Bayes Factor = 13.3753
Chromosome 9   position 105,868,318  (GRCh37) Explore rs12686544 on Ensembl!
Variant rs12686544 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
K70-K77 Diseases of liver
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
K70 Alcoholic liver disease
0.996 0.004 0.000
M25 Other joint disorders, not elsewhere classified
0.995 0.005 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
Chapter IX Diseases of the circulatory system
0.984 0.016 0.000
I30-I52 Other forms of heart disease
0.981 0.019 0.000
E10-E14 Diabetes mellitus
0.977 0.023 0.000
K76 Other diseases of liver
0.976 0.024 0.000
K70.9 Alcoholic liver disease, unspecified
0.964 0.036 0.000
Chapter I Certain infectious and parasitic diseases
0.958 0.042 0.000
I50 Heart failure
0.955 0.045 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.952 0.048 0.000
M25.5 Pain in joint
0.951 0.049 0.000
W00-W19 Falls
0.951 0.049 0.000
K70.3 Alcoholic cirrhosis of liver
0.949 0.051 0.000
M40-M43 Deforming dorsopathies
0.942 0.058 0.000
E14 Unspecified diabetes mellitus
0.942 0.058 0.000
K35-K38 Diseases of appendix
0.941 0.059 0.000
I46 Cardiac arrest
0.939 0.061 0.000
K50-K52 Noninfective enteritis and colitis
0.938 0.062 0.000
M15-M19 Arthrosis
0.933 0.067 0.000
M80-M85 Disorders of bone density and structure
0.931 0.069 0.000
S90-S99 Injuries to the ankle and foot
0.925 0.075 0.000
K51 Ulcerative colitis
0.924 0.076 0.000
E14.9 Without complications
0.922 0.078 0.000
Chapter VI Diseases of the nervous system
0.920 0.080 0.000
M16 Coxarthrosis [arthrosis of hip]
0.918 0.082 0.000
Chapter XIV Diseases of the genitourinary system
0.909 0.091 0.000
W19 Unspecified fall
0.908 0.092 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.906 0.094 0.000
I60-I69 Cerebrovascular diseases
0.904 0.096 0.000
M25.4 Effusion of joint
0.902 0.098 0.000
I46.9 Cardiac arrest, unspecified
0.901 0.099 0.000
M41 Scoliosis
0.898 0.102 0.000
K37 Unspecified appendicitis
0.897 0.103 0.000
K51.9 Ulcerative colitis, unspecified
0.891 0.109 0.000
I49 Other cardiac arrhythmias
0.890 0.110 0.000
X60-X84 Intentional self-harm
0.889 0.111 0.000
Chapter X Diseases of the respiratory system
0.889 0.111 0.000
M86-M90 Other osteopathies
0.889 0.111 0.000
K76.9 Liver disease, unspecified
0.888 0.112 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.887 0.113 0.000
J30-J39 Other diseases of upper respiratory tract
0.885 0.115 0.000
E10 Insulin-dependent diabetes mellitus
0.884 0.116 0.000
K72 Hepatic failure, not elsewhere classified
0.881 0.119 0.000
M16.9 Coxarthrosis, unspecified
0.878 0.122 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.878 0.122 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.877 0.123 0.000
I50.1 Left ventricular failure
0.877 0.123 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.875 0.125 0.000
J34 Other disorders of nose and nasal sinuses
0.874 0.126 0.000
M20 Acquired deformities of fingers and toes
0.871 0.129 0.000
E20-E35 Disorders of other endocrine glands
0.870 0.130 0.000
M70-M79 Other soft tissue disorders
0.870 0.130 0.000
I31 Other diseases of pericardium
0.867 0.133 0.000
M25.7 Osteophyte
0.867 0.133 0.000
M41.9 Scoliosis, unspecified
0.866 0.134 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.866 0.134 0.000
T92 Sequelae of injuries of upper limb
0.862 0.138 0.000
E70-E90 Metabolic disorders
0.861 0.139 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.859 0.141 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.857 0.143 0.000
M81 Osteoporosis without pathological fracture
0.854 0.146 0.000
M25.8 Other specified joint disorders
0.853 0.147 0.000
J32 Chronic sinusitis
0.851 0.149 0.000
K70.4 Alcoholic hepatic failure
0.850 0.150 0.000
J34.2 Deviated nasal septum
0.846 0.154 0.000
M25.57 Pain in joint (Ankle and foot)
0.839 0.161 0.000
Chapter V Mental and behavioural disorders
0.837 0.163 0.000
G90-G99 Other disorders of the nervous system
0.836 0.164 0.000
K76.6 Portal hypertension
0.833 0.167 0.000
A30-A49 Other bacterial diseases
0.833 0.167 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.831 0.169 0.000
W19.4 Street and highway
0.831 0.169 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.829 0.171 0.000
I50.0 Congestive heart failure
0.828 0.172 0.000
M25.51 Pain in joint (Shoulder region)
0.827 0.173 0.000
M25.47 Effusion of joint (Ankle and foot)
0.827 0.173 0.000
M21 Other acquired deformities of limbs
0.823 0.177 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.823 0.177 0.000
I60 Subarachnoid haemorrhage
0.821 0.179 0.000
E40-E46 Malnutrition
0.819 0.181 0.000
S80-S89 Injuries to the knee and lower leg
0.818 0.182 0.000
K76.8 Other specified diseases of liver
0.818 0.182 0.000
M16.1 Other primary coxarthrosis
0.816 0.184 0.000
I50.9 Heart failure, unspecified
0.816 0.184 0.000
M89 Other disorders of bone
0.815 0.185 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.815 0.185 0.000
I51 Complications and ill-defined descriptions of heart disease
0.815 0.185 0.000
S10-S19 Injuries to the neck
0.815 0.185 0.000
M22 Disorders of patella
0.814 0.186 0.000
M20.5 Other deformities of toe(s) (acquired)
0.813 0.187 0.000
I37 Pulmonary valve disorders
0.811 0.189 0.000
G62 Other polyneuropathies
0.809 0.191 0.000
M60-M63 Disorders of muscles
0.808 0.192 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.808 0.192 0.000
B35-B49 Mycoses
0.806 0.194 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.806 0.194 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.806 0.194 0.000
M20.3 Other deformity of hallux (acquired)
0.805 0.195 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.805 0.195 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.803 0.197 0.000
M24 Other specific joint derangements
0.803 0.197 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.800 0.200 0.000
T90 Sequelae of injuries of head
0.799 0.201 0.000
N60-N64 Disorders of breast
0.798 0.202 0.000
M81.9 Osteoporosis, unspecified
0.797 0.203 0.000
J32.9 Chronic sinusitis, unspecified
0.796 0.204 0.000
K72.9 Hepatic failure, unspecified
0.796 0.204 0.000
W19.9 Unspecified place
0.794 0.206 0.000
T79-T79 Certain early complications of trauma
0.793 0.207 0.000
S40-S49 Injuries to the shoulder and upper arm
0.791 0.209 0.000
Chapter VII Diseases of the eye and adnexa
0.790 0.210 0.000
M75 Shoulder lesions
0.789 0.211 0.000
M84 Disorders of continuity of bone
0.788 0.212 0.000
S92 Fracture of foot, except ankle
0.787 0.213 0.000
K70.0 Alcoholic fatty liver
0.785 0.215 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.783 0.217 0.000
N17-N19 Renal failure
0.783 0.217 0.000
N30-N39 Other diseases of urinary system
0.783 0.217 0.000
E10.9 Without complications
0.781 0.219 0.000
M25.53 Pain in joint (Forearm)
0.780 0.220 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.780 0.220 0.000
W07 Fall involving chair
0.778 0.222 0.000
I31.3 Pericardial effusion (noninflammatory)
0.776 0.224 0.000
I49.1 Atrial premature depolarisation
0.775 0.225 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.771 0.229 0.000
S70-S79 Injuries to the hip and thigh
0.768 0.232 0.000
I69 Sequelae of cerebrovascular disease
0.767 0.233 0.000
K75 Other inflammatory liver diseases
0.767 0.233 0.000
I42 Cardiomyopathy
0.766 0.234 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.765 0.235 0.000
A80-A89 Viral infections of the central nervous system
0.765 0.235 0.000
S91 Open wound of ankle and foot
0.765 0.235 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.763 0.237 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.760 0.240 0.000
T66-T78 Other and unspecified effects of external causes
0.759 0.241 0.000
G62.9 Polyneuropathy, unspecified
0.759 0.241 0.000
N10-N16 Renal tubulo-interstitial diseases
0.758 0.242 0.000
K90-K93 Other diseases of the digestive system
0.758 0.242 0.000
M77 Other enthesopathies
0.757 0.243 0.000
L60-L75 Disorders of skin appendages
0.757 0.243 0.000
Chapter VIII Diseases of the ear and mastoid process
0.757 0.243 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.757 0.243 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.757 0.243 0.000
I49.9 Cardiac arrhythmia, unspecified
0.756 0.244 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.756 0.244 0.000
T92.1 Sequelae of fracture of arm
0.754 0.246 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.754 0.246 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.753 0.247 0.000
T18 Foreign body in alimentary tract
0.752 0.248 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.751 0.249 0.000
I05-I09 Chronic rheumatic heart diseases
0.750 0.250 0.000
G91 Hydrocephalus
0.747 0.253 0.000
X62.9 Unspecified place
0.747 0.253 0.000
I20-I25 Ischaemic heart diseases
0.746 0.254 0.000
M25.50 Pain in joint (Multiple sites)
0.746 0.254 0.000
T43.2 Other and unspecified antidepressants
0.744 0.256 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.744 0.256 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.743 0.257 0.000
M89.9 Disorder of bone, unspecified
0.742 0.258 0.000
V40-V49 Car occupant injured in transport accident
0.741 0.259 0.000
M25.52 Pain in joint (Upper arm)
0.740 0.260 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.739 0.261 0.000
M16.0 Primary coxarthrosis, bilateral
0.738 0.262 0.000
T39.0 Salicylates
0.736 0.263 0.000
M18 Arthrosis of first carpometacarpal joint
0.736 0.264 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.736 0.264 0.000
L20-L30 Dermatitis and eczema
0.735 0.265 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.734 0.265 0.000
N30 Cystitis
0.733 0.267 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.733 0.267 0.000
T91 Sequelae of injuries of neck and trunk
0.732 0.268 0.000
B15-B19 Viral hepatitis
0.732 0.268 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
B99-B99 Other infectious diseases
0.731 0.269 0.000
A49 Bacterial infection of unspecified site
0.729 0.270 0.000
I61 Intracerebral haemorrhage
0.729 0.271 0.000
I46.0 Cardiac arrest with successful resuscitation
0.729 0.271 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.728 0.272 0.000
S20-S29 Injuries to the thorax
0.726 0.274 0.000
E13 Other specified diabetes mellitus
0.726 0.274 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.725 0.275 0.000
W18 Other fall on same level
0.725 0.275 0.000
K36 Other appendicitis
0.723 0.277 0.000
M25.78 Osteophyte (Other)
0.723 0.277 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.723 0.277 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.723 0.277 0.000
M25.54 Pain in joint (Hand)
0.722 0.278 0.000
T40.2 Other opioids
0.722 0.278 0.000
T42.4 Benzodiazepines
0.721 0.279 0.000
M00-M03 Infectious arthropathies
0.720 0.279 0.000
G70-G73 Diseases of myoneural junction and muscle
0.720 0.280 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.283 0.000
K73 Chronic hepatitis, not elsewhere classified
0.716 0.283 0.000
K71 Toxic liver disease
0.716 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
W20-W49 Exposure to inanimate mechanical forces
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.715 0.285 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.715 0.285 0.000
S60-S69 Injuries to the wrist and hand
0.715 0.285 0.000
M16.3 Other dysplastic coxarthrosis
0.715 0.285 0.000
N18 Chronic renal failure
0.715 0.285 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.714 0.286 0.000
M25.9 Joint disorder, unspecified
0.713 0.287 0.000
M25.3 Other instability of joint
0.713 0.287 0.000
M25.2 Flail joint
0.713 0.287 0.000
M25.1 Fistula of joint
0.713 0.287 0.000
M25.0 Haemarthrosis
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.713 0.287 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.713 0.287 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.713 0.287 0.000
A00-A09 Intestinal infectious diseases
0.713 0.287 0.000
J34.3 Hypertrophy of nasal turbinates
0.711 0.289 0.000
J32.4 Chronic pansinusitis
0.711 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.711 0.289 0.000
T40.4 Other synthetic narcotics
0.710 0.290 0.000
I51.7 Cardiomegaly
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.709 0.291 0.000
I49.3 Ventricular premature depolarisation
0.709 0.291 0.000
N63 Unspecified lump in breast
0.709 0.291 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
I49.5 Sick sinus syndrome
0.707 0.293 0.000
I00-I02 Acute rheumatic fever
0.706 0.294 0.000
E50-E64 Other nutritional deficiencies
0.705 0.294 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.705 0.295 0.000
I49.0 Ventricular fibrillation and flutter
0.705 0.295 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.705 0.295 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.705 0.295 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.704 0.296 0.000
K65-K67 Diseases of peritoneum
0.704 0.296 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.296 0.000
N61 Inflammatory disorders of breast
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.703 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.703 0.297 0.000
I48 Atrial fibrillation and flutter
0.703 0.297 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.703 0.297 0.000
I41 Myocarditis in diseases classified elsewhere
0.703 0.297 0.000
I40 Acute myocarditis
0.703 0.297 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.703 0.297 0.000
I36 Nonrheumatic tricuspid valve disorders
0.703 0.297 0.000
I32 Pericarditis in diseases classified elsewhere
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.702 0.298 0.000
K51.4 Pseudopolyposis of colon
0.702 0.298 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.702 0.298 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.702 0.298 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.701 0.299 0.000
E12 Malnutrition-related diabetes mellitus
0.700 0.300 0.000
K76.7 Hepatorenal syndrome
0.700 0.300 0.000
K76.5 Hepatic veno-occlusive disease
0.700 0.300 0.000
K76.4 Peliosis hepatis
0.700 0.300 0.000
K76.3 Infarction of liver
0.700 0.300 0.000
K76.2 Central haemorrhagic necrosis of liver
0.700 0.300 0.000
K76.1 Chronic passive congestion of liver
0.700 0.300 0.000
E10.4 With neurological complications
0.700 0.300 0.000
Y86 Sequelae of other accidents
0.699 0.301 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.699 0.301 0.000
S90 Superficial injury of ankle and foot
0.698 0.301 0.000
J32.0 Chronic maxillary sinusitis
0.698 0.302 0.000
I25 Chronic ischaemic heart disease
0.698 0.302 0.000
S99 Other and unspecified injuries of ankle and foot
0.696 0.304 0.000
M71 Other bursopathies
0.696 0.304 0.000
L30 Other dermatitis
0.696 0.304 0.000
G93 Other disorders of brain
0.695 0.305 0.000
M43 Other deforming dorsopathies
0.695 0.305 0.000
E46 Unspecified protein-energy malnutrition
0.694 0.306 0.000
K51.2 Ulcerative (chronic) proctitis
0.693 0.307 0.000
T39.1 4-Aminophenol derivatives
0.692 0.308 0.000
N00-N08 Glomerular diseases
0.692 0.308 0.000
E27 Other disorders of adrenal gland
0.690 0.310 0.000
I37.1 Pulmonary valve insufficiency
0.690 0.310 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.689 0.311 0.000
S89 Other and unspecified injuries of lower leg
0.689 0.311 0.000
K51.5 Mucosal proctocolitis
0.688 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.687 0.312 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.313 0.000
B50-B64 Protozoal diseases
0.687 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.313 0.000
A75-A79 Rickettsioses
0.687 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.687 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.313 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
M25.86 Other specified joint disorders (Lower leg)
0.687 0.313 0.000
I30 Acute pericarditis
0.686 0.314 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.314 0.000
M22.2 Patellofemoral disorders
0.686 0.314 0.000
I47 Paroxysmal tachycardia
0.685 0.315 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.685 0.315 0.000
M34 Systemic sclerosis
0.684 0.315 0.000
K70.1 Alcoholic hepatitis
0.683 0.316 0.000
T93 Sequelae of injuries of lower limb
0.683 0.317 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.683 0.317 0.000
E22 Hyperfunction of pituitary gland
0.683 0.317 0.000
T98 Sequelae of other and unspecified effects of external causes
0.683 0.317 0.000
T95 Sequelae of burns, corrosions and frostbite
0.683 0.317 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.683 0.317 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.683 0.317 0.000
F20 Schizophrenia
0.683 0.317 0.000
I33 Acute and subacute endocarditis
0.682 0.317 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.682 0.318 0.000
M25.59 Pain in joint (Site unspecified)
0.682 0.318 0.000
M25.58 Pain in joint (Other)
0.682 0.318 0.000
W17 Other fall from one level to another
0.681 0.318 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.681 0.318 0.000
W15 Fall from cliff
0.681 0.318 0.000
W14 Fall from tree
0.681 0.318 0.000
W12 Fall on and from scaffolding
0.681 0.318 0.000
W11 Fall on and from ladder
0.681 0.318 0.000
W10 Fall on and from stairs and steps
0.681 0.318 0.000
W09 Fall involving playground equipment
0.681 0.318 0.000
W08 Fall involving other furniture
0.681 0.318 0.000
W06 Fall involving bed
0.681 0.318 0.000
W05 Fall involving wheelchair
0.681 0.318 0.000
W04 Fall while being carried or supported by other persons
0.681 0.318 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.681 0.318 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.681 0.318 0.000
W00 Fall on same level involving ice and snow
0.681 0.318 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.681 0.319 0.000
M35 Other systemic involvement of connective tissue
0.681 0.319 0.000
G20-G26 Extrapyramidal and movement disorders
0.680 0.320 0.000
G40-G47 Episodic and paroxysmal disorders
0.680 0.320 0.000
I45 Other conduction disorders
0.680 0.320 0.000
W19.2 School, other institution and public administrative area
0.680 0.320 0.000
M25.46 Effusion of joint (Lower leg)
0.679 0.321 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.677 0.322 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.677 0.323 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.677 0.323 0.000
T18.1 Foreign body in oesophagus
0.677 0.323 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.677 0.323 0.000
T92.0 Sequelae of open wound of upper limb
0.677 0.323 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.676 0.324 0.000
E10.3 With ophthalmic complications
0.676 0.324 0.000
M42 Spinal osteochondrosis
0.676 0.324 0.000
M40 Kyphosis and lordosis
0.676 0.324 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.676 0.324 0.000
E14.8 With unspecified complications
0.675 0.324 0.000
E14.7 With multiple complications
0.675 0.324 0.000
E14.6 With other specified complications
0.675 0.324 0.000
E14.5 With peripheral circulatory complications
0.675 0.324 0.000
E14.4 With neurological complications
0.675 0.324 0.000
E14.2 Withrenal complications
0.675 0.324 0.000
E14.1 With ketoacidosis
0.675 0.324 0.000
E14.0 With coma
0.675 0.324 0.000
K38 Other diseases of appendix
0.674 0.325 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.674 0.326 0.000
I46.1 Sudden cardiac death, so described
0.673 0.327 0.000
V10-V19 Pedal cyclist injured in transport accident
0.673 0.327 0.000
E80.4 Gilbert's syndrome
0.673 0.327 0.000
E00-E07 Disorders of thyroid gland
0.672 0.328 0.000
L73 Other follicular disorders
0.672 0.328 0.000
M75.3 Calcific tendinitis of shoulder
0.672 0.328 0.000
N18.0 End-stage renal disease
0.671 0.329 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
F60-F69 Disorders of adult personality and behaviour
0.670 0.329 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.670 0.330 0.000
M62 Other disorders of muscle
0.670 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.670 0.330 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.669 0.331 0.000
M15 Polyarthrosis
0.669 0.331 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.668 0.332 0.000
N25-N29 Other disorders of kidney and ureter
0.668 0.332 0.000
M83 Adult osteomalacia
0.668 0.332 0.000
M82 Osteoporosis in diseases classified elsewhere
0.668 0.332 0.000
S32 Fracture of lumbar spine and pelvis
0.667 0.333 0.000
S81 Open wound of lower leg
0.667 0.333 0.000
J39 Other diseases of upper respiratory tract
0.667 0.333 0.000
H43-H45 Disorders of vitreous body and globe
0.666 0.334 0.000
S86 Injury of muscle and tendon at lower leg level
0.666 0.334 0.000
F80-F89 Disorders of psychological development
0.665 0.334 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.665 0.335 0.000
E10.5 With peripheral circulatory complications
0.664 0.336 0.000
S98 Traumatic amputation of ankle and foot
0.663 0.336 0.000
S97 Crushing injury of ankle and foot
0.663 0.336 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.663 0.336 0.000
S95 Injury of blood vessels at ankle and foot level
0.663 0.336 0.000
S94 Injury of nerves at ankle and foot level
0.663 0.336 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.663 0.337 0.000
E85 Amyloidosis
0.663 0.337 0.000
L30.9 Dermatitis, unspecified
0.663 0.337 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.662 0.338 0.000
N11 Chronic tubulo-interstitial nephritis
0.662 0.338 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.662 0.338 0.000
S10 Superficial injury of neck
0.661 0.339 0.000
M86 Osteomyelitis
0.659 0.341 0.000
S40 Superficial injury of shoulder and upper arm
0.659 0.341 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.659 0.341 0.000
B35 Dermatophytosis
0.659 0.341 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.658 0.342 0.000
M16.5 Other posttraumatic coxarthrosis
0.658 0.342 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.658 0.342 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.658 0.342 0.000
I63 Cerebral infarction
0.658 0.342 0.000
N75 Diseases of Bartholin's gland
0.657 0.343 0.000
T31 Burns classified according to extent of body surface involved
0.657 0.343 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.657 0.343 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.656 0.344 0.000
M25.77 Osteophyte (Ankle and foot)
0.654 0.345 0.000
M85 Other disorders of bone density and structure
0.654 0.346 0.000
W19.3 Sports and athletics area
0.654 0.346 0.000
M21.3 Wrist or foot drop (acquired)
0.654 0.346 0.000
M89.8 Other specified disorders of bone
0.652 0.348 0.000
W19.8 Other specified place
0.651 0.349 0.000
W19.5 Trade and service area
0.651 0.349 0.000
W19.0 Home
0.651 0.349 0.000
W19.7 Farm
0.651 0.349 0.000
W19.6 Industrial and construction area
0.651 0.349 0.000
W19.1 Residential institution
0.651 0.349 0.000
T43.9 Psychotropic drug, unspecified
0.650 0.350 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.650 0.350 0.000
T43.6 Psychostimulants with abuse potential
0.650 0.350 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.650 0.350 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.650 0.350 0.000
I31.9 Disease of pericardium, unspecified
0.649 0.351 0.000
S91.3 Open wound of other parts of foot
0.649 0.351 0.000
M90 Osteopathies in diseases classified elsewhere
0.649 0.351 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.648 0.352 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.648 0.352 0.000
K74 Fibrosis and cirrhosis of liver
0.648 0.352 0.000
E11 Non-insulin-dependent diabetes mellitus
0.648 0.352 0.000
K50 Crohn's disease [regional enteritis]
0.648 0.352 0.000
M25.49 Effusion of joint (Site unspecified)
0.647 0.353 0.000
M25.48 Effusion of joint (Other)
0.647 0.353 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.647 0.353 0.000
M25.44 Effusion of joint (Hand)
0.647 0.353 0.000
M25.43 Effusion of joint (Forearm)
0.647 0.353 0.000
M25.42 Effusion of joint (Upper arm)
0.647 0.353 0.000
M25.41 Effusion of joint (Shoulder region)
0.647 0.353 0.000
M25.40 Effusion of joint (Multiple sites)
0.647 0.353 0.000
M25.84 Other specified joint disorders (Hand)
0.646 0.353 0.000
G91.1 Obstructive hydrocephalus
0.646 0.354 0.000
E88 Other metabolic disorders
0.645 0.355 0.000
G62.8 Other specified polyneuropathies
0.645 0.355 0.000
M75.5 Bursitis of shoulder
0.645 0.355 0.000
G30-G32 Other degenerative diseases of the nervous system
0.645 0.355 0.000
W07.0 Home
0.644 0.355 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.644 0.356 0.000
S92.0 Fracture of calcaneus
0.644 0.356 0.000
M41.8 Other forms of scoliosis
0.644 0.356 0.000
M41.5 Other secondary scoliosis
0.644 0.356 0.000
M41.4 Neuromuscular scoliosis
0.644 0.356 0.000
M41.3 Thoracogenic scoliosis
0.644 0.356 0.000
M41.2 Other idiopathic scoliosis
0.644 0.356 0.000
M41.1 Juvenile idiopathic scoliosis
0.644 0.356 0.000
M41.0 Infantile idiopathic scoliosis
0.644 0.356 0.000
F25 Schizoaffective disorders
0.643 0.357 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.643 0.357 0.000
M75.0 Adhesive capsulitis of shoulder
0.643 0.357 0.000
M25.71 Osteophyte (Shoulder region)
0.642 0.358 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.642 0.358 0.000
H02 Other disorders of eyelid
0.641 0.359 0.000
M31 Other necrotising vasculopathies
0.640 0.360 0.000
A46 Erysipelas
0.640 0.360 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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