TreeWAS – Variant ID: rs13037749

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.018	0.982	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.985	0.015
L81.4 Other melanin hyperpigmentation	0.011	0.989	0.000
M85.8 Other specified disorders of bone density and structure	0.011	0.989	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.011	0.989	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.008	0.992	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.008	0.992	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.008	0.992	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.008	0.992	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.008	0.992	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.008	0.992	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.008	0.992	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.008	0.992	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.008	0.992	0.000
C43 Malignant melanoma of skin	0.008	0.992	0.000
C34.9 Bronchus or lung, unspecified	0.007	0.993	0.000
C43.9 Malignant melanoma of skin, unspecified	0.007	0.993	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.007	0.993	0.000
C43.8 Overlapping malignant melanoma of skin	0.006	0.994	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.006	0.994	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.006	0.994	0.000
C43.0 Malignant melanoma of lip	0.006	0.994	0.000
C43.5 Malignant melanoma of trunk	0.006	0.994	0.000
L81 Other disorders of pigmentation	0.006	0.994	0.000
M85 Other disorders of bone density and structure	0.006	0.994	0.000
C43.4 Malignant melanoma of scalp and neck	0.006	0.994	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.006	0.994	0.000
C34 Malignant neoplasm of bronchus and lung	0.005	0.995	0.000
C34.1 Upper lobe, bronchus or lung	0.005	0.995	0.000
L81.8 Other specified disorders of pigmentation	0.005	0.995	0.000
L81.7 Pigmented purpuric dermatosis	0.004	0.996	0.000
L81.6 Other disorders of diminished melanin formation	0.004	0.996	0.000
L81.5 Leukoderma, not elsewhere classified	0.004	0.996	0.000
L81.3 Cafe au lait spots	0.004	0.996	0.000
L81.2 Freckles	0.004	0.996	0.000
L81.1 Chloasma	0.004	0.996	0.000
L81.0 Postinflammatory hyperpigmentation	0.004	0.996	0.000
C34.2 Middle lobe, bronchus or lung	0.004	0.996	0.000
L81.9 Disorder of pigmentation, unspecified	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.996	0.000
M85.6 Other cyst of bone	0.004	0.996	0.000
M85.5 Aneurysmal bone cyst	0.004	0.996	0.000
M85.4 Solitary bone cyst	0.004	0.996	0.000
M85.3 Osteitis condensans	0.004	0.996	0.000
M85.2 Hyperostosis of skull	0.004	0.996	0.000
M85.1 Skeletal fluorosis	0.004	0.996	0.000
M85.0 Fibrous dysplasia (monostotic)	0.004	0.996	0.000
C34.8 Overlapping lesion of bronchus and lung	0.004	0.996	0.000
C34.3 Lower lobe, bronchus or lung	0.004	0.996	0.000
Z47.8 Other specified orthopaedic follow-up care	0.004	0.996	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.004	0.996	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.004	0.996	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.996	0.004
Z04.3 Examination and observation following other accident	0.000	0.997	0.003
C54.1 Endometrium	0.003	0.997	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.003	0.997	0.000
M85.18 Skeletal fluorosis (Other)	0.003	0.997	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.003	0.997	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.003	0.997	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.003	0.997	0.000
M85.14 Skeletal fluorosis (Hand)	0.003	0.997	0.000
M85.13 Skeletal fluorosis (Forearm)	0.003	0.997	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.003	0.997	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.003	0.997	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.003	0.997	0.000
M85.29 Hyperostosis of skull-Site unspec	0.003	0.997	0.000
M85.28 Hyperostosis of skull-Other	0.003	0.997	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.003	0.997	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.003	0.997	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.003	0.997	0.000
M85.24 Hyperostosis of skull-Hand	0.003	0.997	0.000
M85.23 Hyperostosis of skull-Forearm	0.003	0.997	0.000
M85.22 Hyperostosis of skull-Upper arm	0.003	0.997	0.000
M85.21 Hyperostosis of skull-Shldr region	0.003	0.997	0.000
M85.20 Hyperostosis of skull-Mult sites	0.003	0.997	0.000
M85.39 Osteitis condensans (Site unspecified)	0.003	0.997	0.000
M85.38 Osteitis condensans (Other)	0.003	0.997	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.003	0.997	0.000
M85.36 Osteitis condensans (Lower leg)	0.003	0.997	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.003	0.997	0.000
M85.34 Osteitis condensans (Hand)	0.003	0.997	0.000
M85.33 Osteitis condensans (Forearm)	0.003	0.997	0.000
M85.32 Osteitis condensans (Upper arm)	0.003	0.997	0.000
M85.31 Osteitis condensans (Shoulder region)	0.003	0.997	0.000
M85.30 Osteitis condensans (Multiple sites)	0.003	0.997	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.003	0.997	0.000
M85.48 Solitary bone cyst (Other)	0.003	0.997	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.46 Solitary bone cyst (Lower leg)	0.003	0.997	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.44 Solitary bone cyst (Hand)	0.003	0.997	0.000
M85.43 Solitary bone cyst (Forearm)	0.003	0.997	0.000
M85.42 Solitary bone cyst (Upper arm)	0.003	0.997	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.003	0.997	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.003	0.997	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.003	0.997	0.000
M85.58 Aneurysmal bone cyst (Other)	0.003	0.997	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.003	0.997	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.003	0.997	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.003	0.997	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.003	0.997	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.003	0.997	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.003	0.997	0.000
M85.69 Other cyst of bone (Site unspecified)	0.003	0.997	0.000
M85.68 Other cyst of bone (Other)	0.003	0.997	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.003	0.997	0.000
M85.66 Other cyst of bone (Lower leg)	0.003	0.997	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.003	0.997	0.000
M85.64 Other cyst of bone (Hand)	0.003	0.997	0.000
M85.63 Other cyst of bone (Forearm)	0.003	0.997	0.000
M85.62 Other cyst of bone (Upper arm)	0.003	0.997	0.000
M85.61 Other cyst of bone (Shoulder region)	0.003	0.997	0.000
M85.60 Other cyst of bone (Multiple sites)	0.003	0.997	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.003	0.997	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.003	0.997	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.003	0.997	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.003	0.997	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.003	0.997	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.003	0.997	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.003	0.997	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.003	0.997	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.003	0.997	0.000
C34.0 Main bronchus	0.003	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.003	0.997	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.003	0.997	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.003	0.997	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.003	0.997	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.003	0.997	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.003	0.997	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.003	0.997	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.003	0.997	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.003	0.997	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.003	0.997	0.000
Z91.5 Personal history of self-harm	0.000	0.997	0.003
Z47 Other orthopaedic follow-up care	0.003	0.997	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
I10 Essential (primary) hypertension	0.000	0.997	0.003
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.003	0.997	0.000
C78.2 Secondary malignant neoplasm of pleura	0.003	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.003	0.997	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.003	0.997	0.000
C67.6 Ureteric orifice	0.003	0.997	0.000
Z91.7 Personal history of female genital mutilation	0.000	0.997	0.003
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.000	0.997	0.003
Z91.3 Personal history of unhealthy sleep-wake schedule	0.000	0.997	0.003
Z91.2 Personal history of poor personal hygiene	0.000	0.997	0.003
C54 Malignant neoplasm of corpus uteri	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.003	0.997	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.000	0.997	0.003
R04.0 Epistaxis	0.000	0.997	0.003
Z47.9 Orthopaedic follow-up care, unspecified	0.002	0.997	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.003	0.997	0.000
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.002	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.002	0.997	0.000
C31 Malignant neoplasm of accessory sinuses	0.002	0.997	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.002	0.997	0.000
C37 Malignant neoplasm of thymus	0.002	0.997	0.000
C33 Malignant neoplasm of trachea	0.002	0.997	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.997	0.000
M17.1 Other primary gonarthrosis	0.000	0.998	0.002
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
H02.3 Blepharochalasis	0.000	0.998	0.002
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998	0.000
C54.9 Corpus uteri, unspecified	0.002	0.998	0.000
C54.8 Overlapping lesion of corpus uteri	0.002	0.998	0.000
C54.3 Fundus uteri	0.002	0.998	0.000
C54.2 Myometrium	0.002	0.998	0.000
C54.0 Isthmus uteri	0.002	0.998	0.000
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.002	0.998	0.000
Z91.6 Personal history of other physical trauma	0.000	0.998	0.002
C32 Malignant neoplasm of larynx	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.002	0.998	0.000
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
C79 Secondary malignant neoplasm of other sites	0.002	0.998	0.000
C38.4 Pleura	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.002	0.998	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.002	0.998	0.000
C38.3 Mediastinum, part unspecified	0.002	0.998	0.000
C38.2 Posterior mediastinum	0.002	0.998	0.000
C38.1 Anterior mediastinum	0.002	0.998	0.000
C38.0 Heart	0.002	0.998	0.000
C30.1 Middle ear	0.002	0.998	0.000
C30.0 Nasal cavity	0.002	0.998	0.000
C31.9 Accessory sinus, unspecified	0.002	0.998	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.998	0.000
C31.3 Sphenoidal sinus	0.002	0.998	0.000
C31.2 Frontal sinus	0.002	0.998	0.000
C31.1 Ethmoidal sinus	0.002	0.998	0.000
C31.0 Maxillary sinus	0.002	0.998	0.000
C39.9 Ill-defined sites within the respiratory system	0.002	0.998	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.002	0.998	0.000
C39.0 Upper respiratory tract, part unspecified	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
C53.0 Endocervix	0.002	0.998	0.000
Z95.1 Presence of aortocoronary bypass graft	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.002	0.998	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.002	0.998	0.000
C58 Malignant neoplasm of placenta	0.002	0.998	0.000
C52 Malignant neoplasm of vagina	0.002	0.998	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.002	0.998	0.000
C32.1 Supraglottis	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.002	0.998	0.000
C32.3 Laryngeal cartilage	0.002	0.998	0.000
C32.2 Subglottis	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.002	0.998	0.000
C53.1 Exocervix	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
C76.1 Thorax	0.002	0.998	0.000
J86.9 Pyothorax without fistula	0.002	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
C51.8 Overlapping lesion of vulva	0.002	0.998	0.000
C51.2 Clitoris	0.002	0.998	0.000
C51.1 Labium minus	0.002	0.998	0.000
C51.0 Labium majus	0.002	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
R94.3 Abnormal results of cardiovascular function studies	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.002	0.998	0.000
H02.8 Other specified disorders of eyelid	0.000	0.998	0.002
H65 Nonsuppurative otitis media	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
C76.0 Head, face and neck	0.002	0.998	0.000
C57.9 Female genital organ, unspecified	0.001	0.998	0.000
C57.8 Overlapping lesion of female genital organs	0.001	0.998	0.000
C57.7 Other specified female genital organs	0.001	0.998	0.000
C57.4 Uterine adnexa, unspecified	0.001	0.998	0.000
C57.3 Parametrium	0.001	0.998	0.000
C57.2 Round ligament	0.001	0.998	0.000
C57.1 Broad ligament	0.001	0.998	0.000
C57.0 Fallopian tube	0.001	0.998	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.002	0.998	0.000
C76.7 Other ill-defined sites	0.002	0.998	0.000
C76.5 Lower limb	0.002	0.998	0.000
C76.4 Upper limb	0.002	0.998	0.000
C76.3 Pelvis	0.002	0.998	0.000
C76.2 Abdomen	0.002	0.998	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
C74.1 Medulla of adrenal gland	0.002	0.998	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.001	0.998	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.001	0.998	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.001	0.998	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.001	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.001	0.998	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.001	0.998	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.001	0.998	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.001	0.998	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.001	0.998	0.000
C67.7 Urachus	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
C67.1 Dome of bladder	0.002	0.998	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.001	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.001	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.001	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.001	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.001	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.001	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.001	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.001	0.998	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.001	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
C74 Malignant neoplasm of adrenal gland	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D45 Polycythaemia vera	0.002	0.998	0.000
H02 Other disorders of eyelid	0.000	0.998	0.002
M83 Adult osteomalacia	0.001	0.998	0.000
D39.9 Female genital organ, unspecified	0.001	0.998	0.000
D39.7 Other female genital organs	0.001	0.998	0.000
D39.2 Placenta	0.001	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
H80.8 Other otosclerosis	0.001	0.998	0.000
H80.2 Cochlear otosclerosis	0.001	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.998	0.000
C67.2 Lateral wall of bladder	0.001	0.998	0.000
H02.0 Entropion and trichiasis of eyelid	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.998	0.000
C03.1 Lower gum	0.001	0.998	0.000
C74.9 Adrenal gland, unspecified	0.001	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.001	0.998	0.000
H65.0 Acute serous otitis media	0.001	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.998	0.000
H65.2 Chronic serous otitis media	0.001	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.001	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.002
Chapter II Neoplasms	0.002	0.998	0.000
D40.0 Prostate	0.001	0.998	0.000
H65.3 Chronic mucoid otitis media	0.001	0.998	0.000
H93.9 Disorder of ear, unspecified	0.001	0.998	0.000
R04.2 Haemoptysis	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.001	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.001	0.999	0.000
D40.7 Other male genital organs	0.001	0.999	0.000
D44.3 Pituitary gland	0.001	0.999	0.000
H74.0 Tympanosclerosis	0.001	0.999	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.001	0.999	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.001	0.999	0.000
H02.6 Xanthelasma of eyelid	0.000	0.999	0.001
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.001	0.999	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.001	0.999	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.999	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.001	0.999	0.000
H74.1 Adhesive middle ear disease	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.999	0.001
C74.0 Cortex of adrenal gland	0.001	0.999	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.999	0.000
M83.8 Other adult osteomalacia	0.001	0.999	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.999	0.000
M83.4 Aluminum bone disease	0.001	0.999	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.999	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.999	0.000
M83.1 Senile osteomalacia	0.001	0.999	0.000
M83.0 Puerperal osteomalacia	0.001	0.999	0.000
C03 Malignant neoplasm of gum	0.001	0.999	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.999	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.999	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.999	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.999	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.001	0.999	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.001	0.999	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.001	0.999	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.001	0.999	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.001	0.999	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.001	0.999	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.001	0.999	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.001	0.999	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.001	0.999	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.001	0.999	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.001	0.999	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.001	0.999	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.001	0.999	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.001	0.999	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.001	0.999	0.000
C79.2 Secondary malignant neoplasm of skin	0.001	0.999	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.999	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.999	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.999	0.001
Q61.9 Cystic kidney disease, unspecified	0.001	0.999	0.000
H90 Conductive and sensorineural hearing loss	0.001	0.999	0.000
R04 Haemorrhage from respiratory passages	0.000	0.999	0.001
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.999	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
D44.9 Endocrine gland, unspecified	0.001	0.999	0.000
D44.8 Pluriglandular involvement	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
D44.5 Pineal gland	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
D44.2 Parathyroid gland	0.001	0.999	0.000
D44.1 Adrenal gland	0.001	0.999	0.000
D44.0 Thyroid gland	0.001	0.999	0.000
G95.2 Cord compression, unspecified	0.001	0.999	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.999	0.001
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.001	0.999	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
H93.3 Disorders of acoustic nerve	0.001	0.999	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.999	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.999	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
C02 Malignant neoplasm of other and unspecified parts of tongue	0.001	0.999	0.000
Q61 Cystic kidney disease	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.999	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.001	0.999	0.000
C64-C68 Malignant neoplasms of urinary tract	0.001	0.999	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.001	0.999	0.000
H65-H75 Diseases of middle ear and mastoid	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
C02.4 Lingual tonsil	0.001	0.999	0.000
D42.9 Meninges, unspecified	0.001	0.999	0.000
D42.1 Spinal meninges	0.001	0.999	0.000
D42.0 Cerebral meninges	0.001	0.999	0.000
D43.9 Central nervous system, unspecified	0.001	0.999	0.000
D43.7 Other parts of central nervous system	0.001	0.999	0.000
D43.4 Spinal cord	0.001	0.999	0.000
D43.3 Cranial nerves	0.001	0.999	0.000
D43.1 Brain, infratentorial	0.001	0.999	0.000
D43.0 Brain, supratentorial	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.001	0.999	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.999	0.000
D46 Myelodysplastic syndromes	0.001	0.999	0.000
C02.1 Border of tongue	0.001	0.999	0.000
C03.9 Gum, unspecified	0.001	0.999	0.000
C03.0 Upper gum	0.001	0.999	0.000
H93.8 Other specified disorders of ear	0.001	0.999	0.000
Z98.8 Other specified postsurgical states	0.001	0.999	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.001	0.999	0.000
M84 Disorders of continuity of bone	0.001	0.999	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.08 Puerperal osteomalacia (Other)	0.001	0.999	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.001	0.999	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.04 Puerperal osteomalacia (Hand)	0.001	0.999	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.001	0.999	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.001	0.999	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.001	0.999	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.001	0.999	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.18 Senile osteomalacia (Other)	0.001	0.999	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.16 Senile osteomalacia (Lower leg)	0.001	0.999	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.14 Senile osteomalacia (Hand)	0.001	0.999	0.000
M83.13 Senile osteomalacia (Forearm)	0.001	0.999	0.000
M83.12 Senile osteomalacia (Upper arm)	0.001	0.999	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.001	0.999	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.001	0.999	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.001	0.999	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.001	0.999	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.001	0.999	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.001	0.999	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.001	0.999	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.001	0.999	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.001	0.999	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.001	0.999	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.001	0.999	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.001	0.999	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.001	0.999	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.001	0.999	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.001	0.999	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.001	0.999	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.001	0.999	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.001	0.999	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.001	0.999	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.001	0.999	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.001	0.999	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations