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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17088434
log Bayes Factor = 21.3351
Chromosome 18   position 71,513,365  (GRCh37) Explore rs17088434 on Ensembl!
Variant rs17088434 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
K50 Crohn's disease [regional enteritis]
0.996 0.004 0.000
K50-K52 Noninfective enteritis and colitis
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
N18.3 Chronic kidney disease, stage 3
0.993 0.007 0.000
H30-H36 Disorders of choroid and retina
0.993 0.007 0.000
N40-N51 Diseases of male genital organs
0.993 0.007 0.000
M05-M14 Inflammatory polyarthropathies
0.987 0.013 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
C79 Secondary malignant neoplasm of other sites
0.981 0.019 0.000
G90-G99 Other disorders of the nervous system
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
Chapter X Diseases of the respiratory system
0.968 0.032 0.000
N17 Acute renal failure
0.968 0.032 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.967 0.033 0.000
H35 Other retinal disorders
0.966 0.034 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.966 0.034 0.000
M06 Other rheumatoid arthritis
0.965 0.035 0.000
N18.9 Chronic renal failure, unspecified
0.964 0.036 0.000
H55-H59 Other disorders of eye and adnexa
0.957 0.043 0.000
K50.8 Other Crohn's disease
0.955 0.045 0.000
Chapter XXI Factors influencing health status and contact with health services
0.955 0.045 0.000
Chapter XX External causes of morbidity and mortality
0.955 0.045 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.954 0.046 0.000
C64-C68 Malignant neoplasms of urinary tract
0.952 0.048 0.000
K50.9 Crohn's disease, unspecified
0.952 0.048 0.000
M80-M85 Disorders of bone density and structure
0.950 0.050 0.000
N50 Other disorders of male genital organs
0.945 0.055 0.000
K50.0 Crohn's disease of small intestine
0.945 0.055 0.000
N17.9 Acute renal failure, unspecified
0.945 0.055 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.939 0.061 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.939 0.061 0.000
H43-H45 Disorders of vitreous body and globe
0.935 0.065 0.000
K70-K77 Diseases of liver
0.934 0.066 0.000
H36 Retinal disorders in diseases classified elsewhere
0.932 0.068 0.000
K65-K67 Diseases of peritoneum
0.931 0.069 0.000
M06.9 Rheumatoid arthritis, unspecified
0.931 0.069 0.000
Chapter V Mental and behavioural disorders
0.928 0.072 0.000
M05 Seropositive rheumatoid arthritis
0.927 0.073 0.000
K50.1 Crohn's disease of large intestine
0.927 0.073 0.000
N41 Inflammatory diseases of prostate
0.926 0.074 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.926 0.074 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.925 0.075 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.922 0.078 0.000
N00-N08 Glomerular diseases
0.920 0.080 0.000
G93 Other disorders of brain
0.920 0.080 0.000
Chapter I Certain infectious and parasitic diseases
0.919 0.081 0.000
M86-M90 Other osteopathies
0.916 0.084 0.000
N48 Other disorders of penis
0.915 0.085 0.000
E20-E35 Disorders of other endocrine glands
0.914 0.086 0.000
N18.5 Chronic kidney disease, stage 5
0.914 0.086 0.000
F30-F39 Mood [affective] disorders
0.910 0.090 0.000
M50-M54 Other dorsopathies
0.907 0.093 0.000
N50.8 Other specified disorders of male genital organs
0.906 0.094 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.904 0.096 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.901 0.099 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.900 0.100 0.000
K66 Other disorders of peritoneum
0.896 0.104 0.000
Z89 Acquired absence of limb
0.893 0.107 0.000
C78.7 Secondary malignant neoplasm of liver
0.891 0.109 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.890 0.110 0.000
H36.0 Diabetic retinopathy
0.888 0.112 0.000
N41.1 Chronic prostatitis
0.887 0.113 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.885 0.115 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.884 0.116 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.884 0.116 0.000
M54 Dorsalgia
0.883 0.117 0.000
E10-E14 Diabetes mellitus
0.881 0.119 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.881 0.119 0.000
H43 Disorders of vitreous body
0.879 0.121 0.000
J09-J18 Influenza and pneumonia
0.878 0.122 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.877 0.123 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.876 0.124 0.000
F32 Depressive episode
0.876 0.124 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.874 0.126 0.000
Z85 Personal history of malignant neoplasm
0.873 0.127 0.000
G30-G32 Other degenerative diseases of the nervous system
0.872 0.128 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.871 0.129 0.000
G93.3 Postviral fatigue syndrome
0.871 0.129 0.000
E50-E64 Other nutritional deficiencies
0.870 0.130 0.000
Z35 Supervision of high-risk pregnancy
0.869 0.131 0.000
M65-M68 Disorders of synovium and tendon
0.869 0.131 0.000
C80 Malignant neoplasm without specification of site
0.868 0.132 0.000
K66.0 Peritoneal adhesions
0.866 0.134 0.000
N48.6 Balanitis xerotica obliterans
0.865 0.135 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.865 0.135 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.864 0.136 0.000
G95 Other diseases of spinal cord
0.861 0.138 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.861 0.139 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.860 0.140 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.859 0.141 0.000
G40-G47 Episodic and paroxysmal disorders
0.859 0.141 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.857 0.143 0.000
J40-J47 Chronic lower respiratory diseases
0.856 0.144 0.000
H25-H28 Disorders of lens
0.854 0.146 0.000
N99-N99 Other disorders of the genitourinary system
0.854 0.146 0.000
K82 Other diseases of gallbladder
0.851 0.149 0.000
E11 Non-insulin-dependent diabetes mellitus
0.850 0.150 0.000
M06.3 Rheumatoid nodule
0.849 0.151 0.000
C78.2 Secondary malignant neoplasm of pleura
0.848 0.152 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.848 0.152 0.000
K70 Alcoholic liver disease
0.847 0.153 0.000
S10-S19 Injuries to the neck
0.846 0.154 0.000
S20-S29 Injuries to the thorax
0.846 0.154 0.000
F33 Recurrent depressive disorder
0.844 0.155 0.000
J43 Emphysema
0.844 0.156 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.844 0.156 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.844 0.156 0.000
E28 Ovarian dysfunction
0.842 0.157 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.842 0.158 0.000
M54.5 Low back pain
0.841 0.159 0.000
Q50-Q56 Congenital malformations of genital organs
0.840 0.160 0.000
H57 Other disorders of eye and adnexa
0.838 0.162 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.837 0.163 0.000
J43.9 Emphysema, unspecified
0.837 0.163 0.000
G47 Sleep disorders
0.835 0.165 0.000
C67 Malignant neoplasm of bladder
0.833 0.167 0.000
M85 Other disorders of bone density and structure
0.832 0.168 0.000
K86 Other diseases of pancreas
0.831 0.169 0.000
R04 Haemorrhage from respiratory passages
0.831 0.169 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.831 0.169 0.000
Z47 Other orthopaedic follow-up care
0.830 0.170 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.830 0.170 0.000
K83 Other diseases of biliary tract
0.828 0.172 0.000
H35.4 Peripheral retinal degeneration
0.826 0.174 0.000
N18.4 Chronic kidney disease, stage 4
0.826 0.174 0.000
S50-S59 Injuries to the elbow and forearm
0.825 0.175 0.000
K80 Cholelithiasis
0.825 0.175 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.824 0.176 0.000
R04.2 Haemoptysis
0.822 0.178 0.000
M54.59 Low back pain (Site unspecified)
0.821 0.179 0.000
G90 Disorders of autonomic nervous system
0.821 0.179 0.000
N30-N39 Other diseases of urinary system
0.820 0.180 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.820 0.180 0.000
W20-W49 Exposure to inanimate mechanical forces
0.819 0.181 0.000
N18.8 Other chronic renal failure
0.818 0.182 0.000
Z83 Family history of other specific disorders
0.816 0.184 0.000
K72 Hepatic failure, not elsewhere classified
0.816 0.184 0.000
H43.8 Other disorders of vitreous body
0.815 0.185 0.000
B25-B34 Other viral diseases
0.815 0.185 0.000
Z89.4 Acquired absence of foot and ankle
0.813 0.187 0.000
S40-S49 Injuries to the shoulder and upper arm
0.812 0.188 0.000
Chapter VIII Diseases of the ear and mastoid process
0.809 0.191 0.000
M86 Osteomyelitis
0.809 0.191 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.809 0.191 0.000
N18.0 End-stage renal disease
0.806 0.194 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.806 0.194 0.000
C34 Malignant neoplasm of bronchus and lung
0.804 0.196 0.000
N40 Hyperplasia of prostate
0.804 0.196 0.000
X60-X84 Intentional self-harm
0.804 0.196 0.000
R47-R49 Symptoms and signs involving speech and voice
0.804 0.196 0.000
M67 Other disorders of synovium and tendon
0.802 0.198 0.000
F32.9 Depressive episode, unspecified
0.801 0.199 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.801 0.199 0.000
J90-J94 Other diseases of pleura
0.800 0.200 0.000
G91 Hydrocephalus
0.799 0.201 0.000
H33 Retinal detachments and breaks
0.799 0.201 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.799 0.201 0.000
H35.5 Hereditary retinal dystrophy
0.798 0.202 0.000
D70 Agranulocytosis
0.798 0.202 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.798 0.202 0.000
J60-J70 Lung diseases due to external agents
0.797 0.203 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.797 0.203 0.000
M54.9 Dorsalgia, unspecified
0.797 0.203 0.000
C73 Malignant neoplasm of thyroid gland
0.796 0.204 0.000
M82 Osteoporosis in diseases classified elsewhere
0.796 0.204 0.000
C50-C50 Malignant neoplasm of breast
0.795 0.205 0.000
J81 Pulmonary oedema
0.795 0.205 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.794 0.206 0.000
G47.3 Sleep apnoea
0.794 0.206 0.000
E11.5 With peripheral circulatory complications
0.794 0.206 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.793 0.207 0.000
C78.0 Secondary malignant neoplasm of lung
0.793 0.207 0.000
G70-G73 Diseases of myoneural junction and muscle
0.791 0.208 0.000
S80-S89 Injuries to the knee and lower leg
0.791 0.209 0.000
E28.2 Polycystic ovarian syndrome
0.791 0.209 0.000
R30-R39 Symptoms and signs involving the urinary system
0.791 0.209 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.790 0.210 0.000
H26 Other cataract
0.789 0.211 0.000
N48.4 Impotence of organic origin
0.788 0.212 0.000
N46 Male infertility
0.785 0.215 0.000
K82.4 Cholesterolosis of gallbladder
0.785 0.215 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.785 0.215 0.000
H35.9 Retinal disorder, unspecified
0.785 0.215 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.785 0.215 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.784 0.216 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.784 0.216 0.000
H35.3 Degeneration of macula and posterior pole
0.783 0.217 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.781 0.219 0.000
R26 Abnormalities of gait and mobility
0.781 0.219 0.000
R41.0 Disorientation, unspecified
0.780 0.220 0.000
M07 Psoriatic and enteropathic arthropathies
0.779 0.221 0.000
Z35.5 Supervision of elderly primigravida
0.779 0.221 0.000
H31 Other disorders of choroid
0.777 0.222 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.777 0.223 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.776 0.224 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.774 0.226 0.000
Z90.3 Acquired absence of part of stomach
0.774 0.226 0.000
R33 Retention of urine
0.773 0.227 0.000
M84 Disorders of continuity of bone
0.769 0.231 0.000
Z49 Care involving dialysis
0.768 0.232 0.000
Z90.2 Acquired absence of lung [part of]
0.768 0.232 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.768 0.232 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.767 0.233 0.000
Z83.7 Family history of diseases of the digestive system
0.766 0.234 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.766 0.234 0.000
S51 Open wound of forearm
0.765 0.235 0.000
C91 Lymphoid leukaemia
0.764 0.236 0.000
J90 Pleural effusion, not elsewhere classified
0.763 0.237 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.763 0.237 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.762 0.238 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.761 0.239 0.000
K74 Fibrosis and cirrhosis of liver
0.761 0.239 0.000
J80 Adult respiratory distress syndrome
0.761 0.239 0.000
T93 Sequelae of injuries of lower limb
0.760 0.239 0.000
D60-D64 Aplastic and other anaemias
0.760 0.240 0.000
K70.3 Alcoholic cirrhosis of liver
0.760 0.240 0.000
X10-X19 Contact with heat and hot substances
0.760 0.240 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.759 0.241 0.000
Z89.6 Acquired absence of leg above knee
0.759 0.241 0.000
M87 Osteonecrosis
0.758 0.242 0.000
H43.1 Vitreous haemorrhage
0.758 0.242 0.000
Z89.5 Acquired absence of leg at or below knee
0.757 0.243 0.000
D75 Other diseases of blood and blood-forming organs
0.757 0.243 0.000
H35.8 Other specified retinal disorders
0.757 0.243 0.000
N02 Recurrent and persistent haematuria
0.757 0.243 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.754 0.246 0.000
N35 Urethral stricture
0.754 0.246 0.000
Z98 Other postsurgical states
0.753 0.247 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.753 0.247 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.753 0.247 0.000
E11.2 With renal complications
0.753 0.247 0.000
E34 Other endocrine disorders
0.753 0.247 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.752 0.248 0.000
N19 Unspecified renal failure
0.752 0.248 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.752 0.248 0.000
J95-J99 Other diseases of the respiratory system
0.750 0.250 0.000
Y43 Primarily systemic agents
0.750 0.250 0.000
H35.7 Separation of retinal layers
0.750 0.250 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.750 0.250 0.000
E11.3 With ophthalmic complications
0.749 0.251 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.749 0.251 0.000
Z39 Postpartum care and examination
0.748 0.252 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.748 0.252 0.000
H26.4 After-cataract
0.748 0.252 0.000
D00-D09 In situ neoplasms
0.748 0.252 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.747 0.253 0.000
E40-E46 Malnutrition
0.746 0.254 0.000
K35-K38 Diseases of appendix
0.746 0.254 0.000
C67.5 Bladder neck
0.745 0.255 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.744 0.256 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.744 0.256 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.741 0.259 0.000
E26 Hyperaldosteronism
0.740 0.260 0.000
B34 Viral infection of unspecified site
0.740 0.260 0.000
T43.2 Other and unspecified antidepressants
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.738 0.262 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.738 0.262 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.737 0.263 0.000
D73 Diseases of spleen
0.737 0.263 0.000
M67.8 Other specified disorders of synovium and tendon
0.737 0.263 0.000
R50-R69 General symptoms and signs
0.737 0.263 0.000
N30 Cystitis
0.736 0.264 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.736 0.264 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.736 0.264 0.000
H35.0 Background retinopathy and retinal vascular changes
0.736 0.264 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.736 0.264 0.000
N03 Chronic nephritic syndrome
0.735 0.264 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.734 0.266 0.000
C80.9 Malignant neoplasm, unspecified
0.734 0.266 0.000
Z42 Follow-up care involving plastic surgery
0.732 0.268 0.000
Z81 Family history of mental and behavioural disorders
0.731 0.269 0.000
J42 Unspecified chronic bronchitis
0.731 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.729 0.271 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.728 0.272 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.728 0.272 0.000
N41.0 Acute prostatitis
0.727 0.273 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.727 0.273 0.000
E55 Vitamin D deficiency
0.727 0.273 0.000
N25-N29 Other disorders of kidney and ureter
0.727 0.273 0.000
H10-H13 Disorders of conjunctiva
0.727 0.273 0.000
M60-M63 Disorders of muscles
0.726 0.274 0.000
F33.9 Recurrent depressive disorder, unspecified
0.726 0.274 0.000
J11 Influenza, virus not identified
0.726 0.274 0.000
Z99.2 Dependence on renal dialysis
0.723 0.277 0.000
M85.8 Other specified disorders of bone density and structure
0.722 0.278 0.000
T79-T79 Certain early complications of trauma
0.721 0.279 0.000
H44 Disorders of globe
0.719 0.281 0.000
B65-B83 Helminthiases
0.719 0.281 0.000
M81 Osteoporosis without pathological fracture
0.718 0.282 0.000
M11 Other crystal arthropathies
0.718 0.282 0.000
G95.2 Cord compression, unspecified
0.718 0.282 0.000
Z99.1 Dependence on respirator
0.718 0.282 0.000
K86.8 Other specified diseases of pancreas
0.718 0.282 0.000
E29 Testicular dysfunction
0.717 0.282 0.000
H90-H95 Other disorders of ear
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N18.1 Chronic kidney disease, stage 1
0.717 0.283 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
M80 Osteoporosis with pathological fracture
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.713 0.287 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.713 0.287 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.712 0.288 0.000
H30 Chorioretinal inflammation
0.712 0.288 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.712 0.288 0.000
N44 Torsion of testis
0.712 0.288 0.000
C32 Malignant neoplasm of larynx
0.712 0.288 0.000
F32.0 Mild depressive episode
0.712 0.288 0.000
Z48 Other surgical follow-up care
0.712 0.288 0.000
N20-N23 Urolithiasis
0.710 0.290 0.000
N50.0 Atrophy of testis
0.709 0.291 0.000
R42 Dizziness and giddiness
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.708 0.292 0.000
M12 Other specific arthropathies
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M08 Juvenile arthritis
0.708 0.292 0.000
J15.1 Pneumonia due to Pseudomonas
0.708 0.292 0.000
Z31 Procreative management
0.707 0.293 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.707 0.293 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.707 0.293 0.000
C34.9 Bronchus or lung, unspecified
0.706 0.294 0.000
C90.0 Multiple myeloma
0.706 0.294 0.000
S70-S79 Injuries to the hip and thigh
0.706 0.294 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.706 0.294 0.000
N35.9 Urethral stricture, unspecified
0.706 0.294 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
G91.1 Obstructive hydrocephalus
0.705 0.295 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
Q51 Congenital malformations of uterus and cervix
0.704 0.296 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
H60-H62 Diseases of external ear
0.704 0.296 0.000
E53 Deficiency of other B group vitamins
0.704 0.296 0.000
M89 Other disorders of bone
0.704 0.296 0.000
C79.6 Secondary malignant neoplasm of ovary
0.704 0.296 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.704 0.296 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.704 0.296 0.000
R47 Speech disturbances, not elsewhere classified
0.704 0.296 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.704 0.296 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.703 0.297 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.703 0.297 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.703 0.297 0.000
G92 Toxic encephalopathy
0.703 0.297 0.000
G61 Inflammatory polyneuropathy
0.703 0.297 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.703 0.297 0.000
G95.0 Syringomyelia and syringobulbia
0.703 0.297 0.000
M86.9 Osteomyelitis, unspecified
0.702 0.298 0.000
K83.8 Other specified diseases of biliary tract
0.701 0.299 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.701 0.299 0.000
R50 Fever of unknown origin
0.701 0.299 0.000
R40 Somnolence, stupor and coma
0.700 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.300 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.700 0.300 0.000
C15-C26 Malignant neoplasms of digestive organs
0.699 0.301 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.699 0.301 0.000
K66.1 Haemoperitoneum
0.698 0.302 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.698 0.302 0.000
Q38.7 Pharyngeal pouch
0.698 0.302 0.000
Z43 Attention to artificial openings
0.697 0.302 0.000
C67.2 Lateral wall of bladder
0.696 0.304 0.000
K81 Cholecystitis
0.696 0.304 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.696 0.304 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
G47.8 Other sleep disorders
0.695 0.305 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.694 0.306 0.000
N17.8 Other acute renal failure
0.694 0.306 0.000
N17.2 Acute renal failure with medullary necrosis
0.694 0.306 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.694 0.306 0.000
N17.0 Acute renal failure with tubular necrosis
0.694 0.306 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.693 0.306 0.000
G93.6 Cerebral oedema
0.693 0.307 0.000
Y57 Other and unspecified drugs and medicaments
0.693 0.307 0.000
H35.6 Retinal haemorrhage
0.693 0.307 0.000
H35.2 Other proliferative retinopathy
0.693 0.307 0.000
H35.1 Retinopathy of prematurity
0.693 0.307 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.692 0.308 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.692 0.308 0.000
G60 Hereditary and idiopathic neuropathy
0.692 0.308 0.000
M06.8 Other specified rheumatoid arthritis
0.692 0.308 0.000
M06.4 Inflammatory polyarthropathy
0.692 0.308 0.000
M06.2 Rheumatoid bursitis
0.692 0.308 0.000
M06.1 Adult-onset Still's disease
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
N04 Nephrotic syndrome
0.691 0.309 0.000
F80-F89 Disorders of psychological development
0.691 0.309 0.000
J69 Pneumonitis due to solids and liquids
0.691 0.309 0.000
E61 Deficiency of other nutrient elements
0.691 0.309 0.000
K70.1 Alcoholic hepatitis
0.690 0.310 0.000
Z97 Presence of other devices
0.690 0.310 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.690 0.310 0.000
R46 Symptoms and signs involving appearance and behaviour
0.689 0.310 0.000
H55 Nystagmus and other irregular eye movements
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
Q53 Undescended testicle
0.689 0.311 0.000
M54.1 Radiculopathy
0.688 0.311 0.000
Z99.3 Dependence on wheelchair
0.688 0.312 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.688 0.312 0.000
D50-D53 Nutritional anaemias
0.688 0.312 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.687 0.313 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.687 0.313 0.000
B34.9 Viral infection, unspecified
0.687 0.313 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.687 0.313 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.687 0.313 0.000
M40-M43 Deforming dorsopathies
0.686 0.314 0.000
M82.1 Osteoporosis in endocrine disorders
0.686 0.314 0.000
W29 Contact with other powered hand tools and household machinery
0.685 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.685 0.315 0.000
Y00-Y09 Assault
0.685 0.315 0.000
X85-X99 Assault
0.685 0.315 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.685 0.315 0.000
X30-X39 Exposure to forces of nature
0.685 0.315 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.315 0.000
X00-X09 Exposure to smoke, fire and flames
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
W75-W84 Other accidental threats to breathing
0.685 0.315 0.000
W65-W74 Accidental drowning and submersion
0.685 0.315 0.000
V98-V99 Other and unspecified transport accidents
0.685 0.315 0.000
V95-V97 Air and space transport accidents
0.685 0.315 0.000
V90-V94 Water transport accidents
0.685 0.315 0.000
V70-V79 Bus occupant injured in transport accident
0.685 0.315 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.685 0.315 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.685 0.315 0.000
V40-V49 Car occupant injured in transport accident
0.685 0.315 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.685 0.315 0.000
V01-V09 Pedestrian injured in transport accident
0.685 0.315 0.000
Z52 Donors of organs and tissues
0.685 0.315 0.000
Z94 Transplanted organ and tissue status
0.684 0.316 0.000
Z36 Antenatal screening
0.684 0.316 0.000
Y43.3 Other antineoplastic drugs
0.683 0.317 0.000
K72.0 Acute and subacute hepatic failure
0.683 0.317 0.000
B99-B99 Other infectious diseases
0.683 0.317 0.000
M06.34 Rheumatoid nodule (Hand)
0.683 0.317 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.682 0.317 0.000
C66 Malignant neoplasm of ureter
0.682 0.317 0.000
C65 Malignant neoplasm of renal pelvis
0.682 0.317 0.000
E14 Unspecified diabetes mellitus
0.682 0.318 0.000
M83 Adult osteomalacia
0.681 0.318 0.000
G93.9 Disorder of brain, unspecified
0.680 0.319 0.000
B15-B19 Viral hepatitis
0.680 0.320 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.678 0.322 0.000
G96 Other disorders of central nervous system
0.678 0.322 0.000
N50.1 Vascular disorders of male genital organs
0.678 0.322 0.000
N50.9 Disorder of male genital organs, unspecified
0.678 0.322 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
R53 Malaise and fatigue
0.676 0.324 0.000
N48.9 Disorder of penis, unspecified
0.676 0.324 0.000
G93.0 Cerebral cysts
0.675 0.325 0.000
Z46 Fitting and adjustment of other devices
0.675 0.325 0.000
R50.9 Fever, unspecified
0.674 0.326 0.000
M06.0 Seronegative rheumatoid arthritis
0.674 0.326 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.673 0.326 0.000
S27 Injury of other and unspecified intrathoracic organs
0.673 0.327 0.000
Y85 Sequelae of transport accidents
0.673 0.327 0.000
T91 Sequelae of injuries of neck and trunk
0.673 0.327 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.673 0.327 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.673 0.327 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.673 0.327 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.673 0.327 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.673 0.327 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.673 0.327 0.000
Q35-Q37 Cleft lip and cleft palate
0.673 0.327 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.673 0.327 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.673 0.327 0.000
M54.55 Low back pain (Thoracolumbar region)
0.673 0.327 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.673 0.327 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.672 0.328 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.672 0.328 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.672 0.328 0.000
N45 Orchitis and epididymitis
0.672 0.328 0.000
G93.8 Other specified disorders of brain
0.672 0.328 0.000
H57.0 Anomalies of pupillary function
0.672 0.328 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.671 0.329 0.000
N48.2 Other inflammatory disorders of penis
0.671 0.329 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.671 0.329 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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