TreeWAS – Variant ID: rs2770102

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G20 Parkinson's disease	0.063	0.937	0.000
G20-G26 Extrapyramidal and movement disorders	0.034	0.966	0.000
G24 Dystonia	0.030	0.970	0.000
G23 Other degenerative diseases of basal ganglia	0.026	0.974	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.974	0.026
G24.3 Spasmodic torticollis	0.025	0.975	0.000
G21 Secondary Parkinsonism	0.025	0.975	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.025	0.975	0.000
G22 Parkinsonism in diseases classified elsewhere	0.025	0.975	0.000
G24.8 Other dystonia	0.025	0.975	0.000
G24.5 Blepharospasm	0.024	0.976	0.000
G24.0 Drug-induced dystonia	0.022	0.978	0.000
G24.4 Idiopathic orofacial dystonia	0.021	0.979	0.000
G24.2 Idiopathic nonfamilial dystonia	0.021	0.979	0.000
G24.1 Idiopathic familial dystonia	0.021	0.979	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.021	0.979	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.020	0.980	0.000
G25 Other extrapyramidal and movement disorders	0.019	0.981	0.000
R10.3 Pain localised to other parts of lower abdomen	0.019	0.981	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.019	0.981	0.000
G23.3 Multiple system atrophy, cerebellar type	0.019	0.981	0.000
G23.2 Striatonigral degeneration	0.019	0.981	0.000
G23.0 Hallervorden-Spatz disease	0.019	0.981	0.000
C25.0 Head of pancreas	0.000	0.981	0.019
G23.8 Other specified degenerative diseases of basal ganglia	0.018	0.982	0.000
G21.9 Secondary Parkinsonism, unspecified	0.018	0.982	0.000
G21.8 Other secondary Parkinsonism	0.018	0.982	0.000
G21.3 Postencephalitic Parkinsonism	0.018	0.982	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.018	0.982	0.000
C25 Malignant neoplasm of pancreas	0.000	0.982	0.018
C25.9 Pancreas, unspecified	0.000	0.982	0.018
G21.4 Vascular parkinsonism	0.017	0.982	0.000
G21.0 Malignant neuroleptic syndrome	0.017	0.982	0.000
G25.2 Other specified forms of tremor	0.016	0.984	0.000
G25.1 Drug-induced tremor	0.016	0.984	0.000
C25.7 Other parts of pancreas	0.000	0.984	0.016
C25.1 Body of pancreas	0.000	0.985	0.015
C25.2 Tail of pancreas	0.000	0.985	0.015
G25.9 Extrapyramidal and movement disorder, unspecified	0.014	0.986	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.014	0.986	0.000
G25.4 Drug-induced chorea	0.014	0.986	0.000
G25.5 Other chorea	0.014	0.986	0.000
G24.9 Dystonia, unspecified	0.013	0.987	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.987	0.013
G25.8 Other specified extrapyramidal and movement disorders	0.013	0.987	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.987	0.013
G25.0 Essential tremor	0.013	0.987	0.000
C25.4 Endocrine pancreas	0.000	0.988	0.012
C25.3 Pancreatic duct	0.000	0.989	0.011
G31.9 Degenerative disease of nervous system, unspecified	0.009	0.991	0.000
G35 Multiple sclerosis	0.008	0.992	0.000
J00 Acute nasopharyngitis [common cold]	0.008	0.992	0.000
Q05.9 Spina bifida, unspecified	0.008	0.992	0.000
K70 Alcoholic liver disease	0.000	0.993	0.007
K74 Fibrosis and cirrhosis of liver	0.000	0.993	0.007
K70.4 Alcoholic hepatic failure	0.000	0.993	0.007
K43.0 Ventral hernia with obstruction, without gangrene	0.007	0.993	0.000
G12.2 Motor neuron disease	0.007	0.993	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.994	0.006
G25.3 Myoclonus	0.005	0.994	0.001
K74.1 Hepatic sclerosis	0.000	0.994	0.005
Q05 Spina bifida	0.006	0.994	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.006	0.994	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.994	0.005
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.994	0.005
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.995	0.005
G12 Spinal muscular atrophy and related syndromes	0.005	0.995	0.000
K74.0 Hepatic fibrosis	0.000	0.995	0.005
K70.9 Alcoholic liver disease, unspecified	0.000	0.995	0.005
M81.98 Osteoporosis, unspecified (Other)	0.000	0.995	0.005
G35-G37 Demyelinating diseases of the central nervous system	0.005	0.995	0.000
K75 Other inflammatory liver diseases	0.000	0.995	0.005
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.995	0.005
K70.1 Alcoholic hepatitis	0.000	0.995	0.005
K70-K77 Diseases of liver	0.000	0.995	0.005
Z97.4 Presence of external hearing-aid	0.000	0.996	0.004
G31.2 Degeneration of nervous system due to alcohol	0.004	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.996	0.004
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.004	0.996	0.000
G12.9 Spinal muscular atrophy, unspecified	0.004	0.996	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.004	0.996	0.000
G12.1 Other inherited spinal muscular atrophy	0.004	0.996	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
G31.0 Circumscribed brain atrophy	0.004	0.996	0.000
K70.0 Alcoholic fatty liver	0.000	0.996	0.004
D25.2 Subserosal leiomyoma of uterus	0.004	0.996	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.996	0.004
K75.1 Phlebitis of portal vein	0.000	0.996	0.004
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.004	0.996	0.000
G36 Other acute disseminated demyelination	0.004	0.996	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.996	0.004
K75.9 Inflammatory liver disease, unspecified	0.000	0.996	0.004
G37 Other demyelinating diseases of central nervous system	0.003	0.996	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.996	0.003
Q06 Other congenital malformations of spinal cord	0.003	0.996	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.996	0.004
G31.8 Other specified degenerative diseases of nervous system	0.003	0.996	0.000
G30-G32 Other degenerative diseases of the nervous system	0.003	0.996	0.000
G14 Postpolio syndrome	0.003	0.997	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
D25.1 Intramural leiomyoma of uterus	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Chapter VI Diseases of the nervous system	0.003	0.997	0.000
K75.0 Abscess of liver	0.000	0.997	0.003
K77 Liver disorders in diseases classified elsewhere	0.000	0.997	0.003
Z50.2 Alcohol rehabilitation	0.000	0.997	0.003
D09.0 Bladder	0.000	0.997	0.003
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.997	0.000
G10 Huntington's disease	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.000	0.997	0.003
K71 Toxic liver disease	0.000	0.997	0.003
K75.4 Autoimmune hepatitis	0.000	0.997	0.003
S50.0 Contusion of elbow	0.000	0.997	0.003
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.003	0.997	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.003	0.997	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.003	0.997	0.000
G36.9 Acute disseminated demyelination, unspecified	0.003	0.997	0.000
G36.8 Other specified acute disseminated demyelination	0.003	0.997	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.003	0.997	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.003	0.997	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.997	0.003
Z48.9 Surgical follow-up care, unspecified	0.000	0.997	0.003
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.003	0.997	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.997	0.003
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.997	0.003
G36.0 Neuromyelitis optica [Devic]	0.003	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.997	0.000
S01.2 Open wound of nose	0.000	0.997	0.003
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.997	0.000
Q06.4 Hydromyelia	0.003	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.997	0.000
Q06.2 Diastematomyelia	0.003	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.997	0.000
Q06.0 Amyelia	0.003	0.997	0.000
M79.18 Myalgia (Other)	0.000	0.997	0.003
Q07.0 Arnold-Chiari syndrome	0.003	0.997	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.997	0.003
M79.1 Myalgia	0.000	0.997	0.003
D22.0 Melanocytic naevi of lip	0.000	0.997	0.003
Q04.9 Congenital malformation of brain, unspecified	0.003	0.997	0.000
Q04.5 Megalencephaly	0.003	0.997	0.000
Q04.4 Septo-optic dysplasia	0.003	0.997	0.000
Q04.3 Other reduction deformities of brain	0.003	0.997	0.000
Q04.2 Holoprosencephaly	0.003	0.997	0.000
Q04.1 Arhinencephaly	0.003	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.003	0.997	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.997	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.997	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.003	0.997	0.000
Q00.2 Iniencephaly	0.002	0.997	0.000
Q00.1 Craniorachischisis	0.002	0.997	0.000
Q00.0 Anencephaly	0.002	0.997	0.000
Q01.9 Encephalocele, unspecified	0.002	0.997	0.000
Q01.8 Encephalocele of other sites	0.002	0.997	0.000
Q01.2 Occipital encephalocele	0.002	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.997	0.000
Q01.0 Frontal encephalocele	0.002	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.997	0.002
K71.8 Toxic liver disease with other disorders of liver	0.000	0.998	0.002
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.998	0.002
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.998	0.002
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.998	0.002
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.998	0.002
K71.2 Toxic liver disease with acute hepatitis	0.000	0.998	0.002
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
R41.3 Other amnesia	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.002
M79.10 Myalgia (Multiple sites)	0.000	0.998	0.002
K71.0 Toxic liver disease with cholestasis	0.000	0.998	0.002
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.998	0.002
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.002	0.998	0.000
M79.16 Myalgia (Lower leg)	0.000	0.998	0.002
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.998	0.002
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
G11 Hereditary ataxia	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.000	0.998	0.002
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
K71.9 Toxic liver disease, unspecified	0.000	0.998	0.002
L29.8 Other pruritus	0.002	0.998	0.000
M79.17 Myalgia (Ankle and foot)	0.000	0.998	0.002
M79.14 Myalgia (Hand)	0.000	0.998	0.002
M79.13 Myalgia (Forearm)	0.000	0.998	0.002
M79.12 Myalgia (Upper arm)	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.002
Y57.6 Other diagnostic agents	0.002	0.998	0.000
N30.0 Acute cystitis	0.000	0.998	0.002
N48.4 Impotence of organic origin	0.002	0.998	0.000
K73 Chronic hepatitis, not elsewhere classified	0.001	0.998	0.001
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
D09 Carcinoma in situ of other and unspecified sites	0.000	0.998	0.002
S91.0 Open wound of ankle	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Z94.1 Heart transplant status	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.998	0.002
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.998	0.002
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.998	0.002
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.002	0.998	0.000
H27.8 Other specified disorders of lens	0.000	0.998	0.002
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.002	0.998	0.000
N30.9 Cystitis, unspecified	0.000	0.998	0.002
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.998	0.002
G11.8 Other hereditary ataxias	0.002	0.998	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.002	0.998	0.000
G11.2 Late-onset cerebellar ataxia	0.002	0.998	0.000
G11.0 Congenital nonprogressive ataxia	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
M79.64 Pain in limb (Hand)	0.002	0.998	0.000
G11.1 Early-onset cerebellar ataxia	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.998	0.002
K72.1 Chronic hepatic failure	0.000	0.998	0.002
L50.0 Allergic urticaria	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.998	0.002
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.998	0.002
K72.0 Acute and subacute hepatic failure	0.000	0.998	0.002
H40.8 Other glaucoma	0.000	0.998	0.002
I86.4 Gastric varices	0.000	0.998	0.002
M16.0 Primary coxarthrosis, bilateral	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.000	0.998	0.002
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.001	0.998	0.001
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.001	0.998	0.001
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
N63 Unspecified lump in breast	0.002	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
D09.7 Carcinoma in situ of other specified sites	0.000	0.998	0.002
D09.3 Thyroid and other endocrine glands	0.000	0.998	0.002
D09.2 Eye	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.001	0.998	0.001
L23.9 Allergic contact dermatitis, unspecified cause	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.001	0.998	0.001
D25 Leiomyoma of uterus	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.000	0.998	0.002
K73.8 Other chronic hepatitis, not elsewhere classified	0.001	0.998	0.001
R94.5 Abnormal results of liver function studies	0.000	0.998	0.002
L29 Pruritus	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.002	0.998	0.000
D12.3 Transverse colon	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.001	0.998	0.001
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.998	0.002
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.998	0.002
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.998	0.002
K73.2 Chronic active hepatitis, not elsewhere classified	0.001	0.998	0.001
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.998	0.002
J95.0 Tracheostomy malfunction	0.000	0.998	0.002
K73.9 Chronic hepatitis, unspecified	0.001	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.998	0.002
C32.0 Glottis	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.001	0.998	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.998	0.001
Z94.2 Lung transplant status	0.002	0.998	0.000
H27.0 Aphakia	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
L29.3 Anogenital pruritus, unspecified	0.002	0.998	0.000
K43 Ventral hernia	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.998	0.002
I77.1 Stricture of artery	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I84.3 External thrombosed haemorrhoids	0.000	0.998	0.002
G60.8 Other hereditary and idiopathic neuropathies	0.002	0.998	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
L29.1 Pruritus scroti	0.001	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
K43.1 Ventral hernia with gangrene	0.001	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.001	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
Z94.7 Corneal transplant status	0.001	0.998	0.000
L23 Allergic contact dermatitis	0.001	0.998	0.000
D23.4 Skin of scalp and neck	0.000	0.998	0.002
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
D10.3 Other and unspecified parts of mouth	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
H81.1 Benign paroxysmal vertigo	0.001	0.999	0.000
I20.8 Other forms of angina pectoris	0.000	0.999	0.001
G46.4 Cerebellar stroke syndrome	0.001	0.999	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.001	0.999	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.001	0.999	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.001	0.999	0.000
K43.4 Parastomal hernia with gangrene	0.001	0.999	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.001	0.999	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.001	0.999	0.000
G82.1 Spastic paraplegia	0.001	0.999	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.999	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I98.0 Cardiovascular syphilis	0.000	0.999	0.001
J21.9 Acute bronchiolitis, unspecified	0.000	0.999	0.001
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.999	0.000
X68.9 Unspecified place	0.001	0.999	0.000
G60 Hereditary and idiopathic neuropathy	0.001	0.999	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.999	0.001
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.999	0.001
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.001	0.999	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.999	0.001
E61.1 Iron deficiency	0.000	0.999	0.001
G94.1 Hydrocephalus in neoplastic disease	0.000	0.999	0.001
K80.4 Calculus of bile duct with cholecystitis	0.001	0.999	0.000
M81.2 Osteoporosis of disuse	0.000	0.999	0.001
G64 Other disorders of peripheral nervous system	0.001	0.999	0.000
H27 Other disorders of lens	0.000	0.999	0.001
M25.33 Other instability of joint (Forearm)	0.000	0.999	0.001
G62.1 Alcoholic polyneuropathy	0.001	0.999	0.000
R30.9 Painful micturition, unspecified	0.000	0.999	0.001
G70-G73 Diseases of myoneural junction and muscle	0.001	0.999	0.000
M25.37 Other instability of joint (Ankle and foot)	0.000	0.999	0.001
L23.8 Allergic contact dermatitis due to other agents	0.001	0.999	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.001	0.999	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.001	0.999	0.000
L23.4 Allergic contact dermatitis due to dyes	0.001	0.999	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.001	0.999	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.001	0.999	0.000
L23.0 Allergic contact dermatitis due to metals	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
Q89.2 Congenital malformations of other endocrine glands	0.001	0.999	0.000
S41.1 Open wound of upper arm	0.000	0.999	0.001
M79.80 Other specified soft tissue disorders (Multiple sites)	0.001	0.999	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.001	0.999	0.000
M07.6 Other enteropathic arthropathies	0.000	0.999	0.001
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.999	0.001
Q89.0 Congenital malformations of spleen	0.001	0.999	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.999	0.001
Z04.9 Examination and observation for unspecified reason	0.000	0.999	0.001
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.999	0.001
M07 Psoriatic and enteropathic arthropathies	0.000	0.999	0.001
Q89 Other congenital malformations, not elsewhere classified	0.001	0.999	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.999	0.001
G41.2 Complex partial status epilepticus	0.001	0.999	0.000
G60.3 Idiopathic progressive neuropathy	0.001	0.999	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.001	0.999	0.000
G60.1 Refsum's disease	0.001	0.999	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.999	0.001
G80-G83 Cerebral palsy and other paralytic syndromes	0.001	0.999	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.999	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.999	0.001
M81.28 Osteoporosis of disuse (Other)	0.000	0.999	0.001
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.999	0.001
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.999	0.001
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.999	0.001
M81.24 Osteoporosis of disuse (Hand)	0.000	0.999	0.001
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.999	0.001
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.999	0.001
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.999	0.001
C41.1 Mandible	0.000	0.999	0.001
H27.9 Disorder of lens, unspecified	0.000	0.999	0.001
H43.8 Other disorders of vitreous body	0.001	0.999	0.000
Q82.0 Hereditary lymphoedema	0.001	0.999	0.000
G30 Alzheimer's disease	0.001	0.999	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.001	0.999	0.000
M51.3 Other specified intervertebral disk degeneration	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.999	0.000
Q61.4 Renal dysplasia	0.000	0.999	0.001
S52.6 Fracture of lower end of both ulna and radius	0.001	0.999	0.000
T86.0 Bone-marrow transplant rejection	0.001	0.999	0.000
V23.5 Passenger injured in traffic accident	0.000	0.999	0.001
L21 Seborrhoeic dermatitis	0.001	0.999	0.000
M51 Other intervertebral disk disorders	0.001	0.999	0.000
M07.68 Other enteropathic arthropathies (Other)	0.000	0.999	0.001
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.999	0.001
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.999	0.001
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.999	0.001
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.999	0.001
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.999	0.001
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.999	0.001
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.999	0.001
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.999	0.001
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
G83.8 Other specified paralytic syndromes	0.001	0.999	0.000
M51.4 Schmorl's nodes	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.999	0.001
Q82 Other congenital malformations of skin	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.001	0.999	0.000
Q61 Cystic kidney disease	0.000	0.999	0.001
S42.20 Fracture of upper end of humerus (closed)	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.001	0.999	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.001	0.999	0.000
M07.5 Arthropathy in ulcerative colitis	0.000	0.999	0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.999	0.001
M07.2 Psoriatic spondylitis	0.000	0.999	0.001
M07.1 Arthritis mutilans	0.000	0.999	0.001
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.999	0.001
Q89.9 Congenital malformation, unspecified	0.001	0.999	0.000
Q89.8 Other specified congenital malformations	0.001	0.999	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.999	0.000
Q89.4 Conjoined twins	0.001	0.999	0.000
Q89.3 Situs inversus	0.001	0.999	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.999	0.000
S05.8 Other injuries of eye and orbit	0.000	0.999	0.001
Z94.6 Bone transplant status	0.001	0.999	0.000
Z94 Transplanted organ and tissue status	0.001	0.999	0.000
M25.74 Osteophyte (Hand)	0.000	0.999	0.001
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.999	0.001
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.999	0.001
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.999	0.001
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.999	0.001
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.999	0.001
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.999	0.001
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.999	0.001
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.999	0.001
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.999	0.001
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.001	0.999	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.001	0.999	0.000
H50.9 Strabismus, unspecified	0.001	0.999	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.001	0.999	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.999	0.001
Q61.9 Cystic kidney disease, unspecified	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.999	0.001
H27.1 Dislocation of lens	0.000	0.999	0.001
I35.9 Aortic valve disorder, unspecified	0.000	0.999	0.001
L20.9 Atopic dermatitis, unspecified	0.001	0.999	0.000
L21.8 Other seborrhoeic dermatitis	0.001	0.999	0.000
L21.1 Seborrhoeic infantile dermatitis	0.001	0.999	0.000
L21.0 Seborrhoea capitis	0.001	0.999	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.001	0.999	0.000
Q82.2 Mastocytosis	0.001	0.999	0.000
R87.7 Abnormal histological findings	0.000	0.999	0.001
W17.6 Industrial and construction area	0.000	0.999	0.001
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.999	0.000
M40.56 Lordosis, unspecified (Lumbar region)	0.000	0.999	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.000	0.999	0.001
G41.9 Status epilepticus, unspecified	0.001	0.999	0.000
G73.7 Myopathy other diseases classified elsewhere	0.001	0.999	0.000
G82.0 Flaccid paraplegia	0.001	0.999	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations