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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3887152
log Bayes Factor = 90.6599
Chromosome 6   position 31,176,335  (GRCh37) Explore rs3887152 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
M06.3 Rheumatoid nodule
0.994 0.006 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
M05.9 Seropositive rheumatoid arthritis, unspecified
0.992 0.008 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.990 0.010 0.000
M05 Seropositive rheumatoid arthritis
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.987 0.013 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.987 0.013 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.986 0.014 0.000
M06.34 Rheumatoid nodule (Hand)
0.986 0.014 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.016 0.984
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.965 0.035 0.000
L40.0 Psoriasis vulgaris
0.000 0.037 0.963
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.928 0.072 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.920 0.080 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.910 0.090 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.902 0.098 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.896 0.104 0.000
J45.9 Asthma, unspecified
0.894 0.106 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.884 0.116 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.126 0.874
E06 Thyroiditis
0.000 0.127 0.873
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.151 0.849
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.154 0.846
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.160 0.840
D72 Other disorders of white blood cells
0.000 0.180 0.820
D69 Purpura and other haemorrhagic conditions
0.000 0.184 0.816
D70 Agranulocytosis
0.000 0.188 0.812
D60-D64 Aplastic and other anaemias
0.000 0.190 0.810
D80-D89 Certain disorders involving the immune mechanism
0.000 0.190 0.810
D69.6 Thrombocytopenia, unspecified
0.000 0.191 0.809
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.801 0.199 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.201 0.799
E06.3 Autoimmune thyroiditis
0.000 0.205 0.795
D61 Other aplastic anaemias
0.000 0.206 0.794
L40.1 Generalised pustular psoriasis
0.000 0.211 0.789
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.781 0.218 0.000
D61.9 Aplastic anaemia, unspecified
0.000 0.221 0.779
M12 Other specific arthropathies
0.778 0.222 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.228 0.772
M06.0 Seronegative rheumatoid arthritis
0.768 0.232 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.764 0.236 0.000
D66 Hereditary factor VIII deficiency
0.000 0.241 0.759
L40.4 Guttate psoriasis
0.000 0.243 0.757
M06.32 Rheumatoid nodule (Upper arm)
0.756 0.244 0.000
M06.33 Rheumatoid nodule (Forearm)
0.755 0.245 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.749 0.251 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.747 0.253 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.255 0.745
M06.98 Rheumatoid arthritis, unspecified (Other)
0.742 0.258 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.741 0.259 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.262 0.738
M14 Arthropathies in other diseases classified elsewhere
0.731 0.269 0.000
M05.1 Rheumatoid lung disease
0.726 0.273 0.000
M08 Juvenile arthritis
0.726 0.274 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.274 0.726
E03.8 Other specified hypothyroidism
0.000 0.276 0.724
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.721 0.278 0.000
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E06.9 Thyroiditis, unspecified
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.284 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.715
D86 Sarcoidosis
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
M06.39 Rheumatoid nodule (Site unspecified)
0.713 0.287 0.000
M06.38 Rheumatoid nodule (Other)
0.713 0.287 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.713 0.287 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.713 0.287 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.711 0.288 0.000
D69.2 Other nonthrombocytopenic purpura
0.000 0.290 0.710
M06.37 Rheumatoid nodule (Ankle and foot)
0.710 0.290 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.709 0.291 0.000
M05.2 Rheumatoid vasculitis
0.709 0.291 0.000
M05.0 Felty's syndrome
0.709 0.291 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.292 0.708
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.707 0.293 0.000
M05.8 Other seropositive rheumatoid arthritis
0.704 0.295 0.000
L40.8 Other psoriasis
0.000 0.312 0.687
D64 Other anaemias
0.000 0.314 0.686
D55-D59 Haemolytic anaemias
0.000 0.316 0.684
D69.4 Other primary thrombocytopenia
0.000 0.319 0.681
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.323 0.676
M06.4 Inflammatory polyarthropathy
0.670 0.330 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.331 0.669
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.340 0.660
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.345 0.655
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.651 0.349 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.644 0.356 0.000
D73 Diseases of spleen
0.000 0.361 0.639
D84 Other immunodeficiencies
0.000 0.365 0.635
D86.3 Sarcoidosis of skin
0.000 0.367 0.633
D61.0 Constitutional aplastic anaemia
0.000 0.370 0.630
D86.9 Sarcoidosis, unspecified
0.000 0.374 0.626
E06.4 Drug-induced thyroiditis
0.000 0.374 0.626
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.374 0.626
E06.0 Acute thyroiditis
0.000 0.374 0.626
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.625 0.375 0.000
D83 Common variable immunodeficiency
0.000 0.377 0.623
E05.8 Other thyrotoxicosis
0.000 0.380 0.620
D69.1 Qualitative platelet defects
0.000 0.392 0.608
D74 Methaemoglobinaemia
0.000 0.393 0.607
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.393 0.607
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.393 0.607
D72.1 Eosinophilia
0.000 0.395 0.605
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.403 0.597
D59 Acquired haemolytic anaemia
0.000 0.405 0.595
M12.2 Villonodular synovitis (pigmented)
0.592 0.408 0.000
D68 Other coagulation defects
0.000 0.409 0.591
M12.5 Traumatic arthropathy
0.591 0.409 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.410 0.590
D72.9 Disorder of white blood cells, unspecified
0.000 0.412 0.588
D72.0 Genetic anomalies of leukocytes
0.000 0.412 0.588
M14.8 Arthropathies in other specified diseases classified elsewhere
0.587 0.413 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.415 0.585
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.585 0.415 0.000
E06.5 Other chronic thyroiditis
0.000 0.419 0.581
D81 Combined immunodeficiencies
0.000 0.419 0.580
D64.8 Other specified anaemias
0.000 0.421 0.579
D67 Hereditary factor IX deficiency
0.000 0.421 0.579
D89.1 Cryoglobulinaemia
0.000 0.423 0.577
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.428 0.572
M06.04 Seronegative rheumatoid arthritis (Hand)
0.570 0.430 0.000
D61.8 Other specified aplastic anaemias
0.000 0.430 0.569
D61.3 Idiopathic aplastic anaemia
0.000 0.430 0.569
D61.2 Aplastic anaemia due to other external agents
0.000 0.430 0.569
M12.3 Palindromic rheumatism
0.569 0.430 0.000
D61.1 Drug-induced aplastic anaemia
0.000 0.435 0.565
M12.8 Other specific arthropathies, not elsewhere classified
0.558 0.442 0.000
M12.4 Intermittent hydrarthrosis
0.558 0.442 0.000
M12.1 Kaschin-Beck disease
0.558 0.442 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.558 0.442 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.551 0.449 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.551 0.449 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.551 0.449 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.551 0.449 0.000
D75 Other diseases of blood and blood-forming organs
0.000 0.451 0.549
D69.5 Secondary thrombocytopenia
0.000 0.453 0.547
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.455 0.545
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.456 0.544
M08.2 Juvenile arthritis with systemic onset
0.539 0.461 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.538 0.462 0.000
D68.8 Other specified coagulation defects
0.000 0.468 0.532
D86.0 Sarcoidosis of lung
0.000 0.468 0.532
D76.3 Other histiocytosis syndromes
0.000 0.473 0.527
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.474 0.526
D64.9 Anaemia, unspecified
0.000 0.476 0.524
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.524 0.476 0.000
M14.4 Arthropathy in amyloidosis
0.524 0.476 0.000
M14.3 Lipoid dermatoarthritis
0.524 0.476 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.524 0.476 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.524 0.476 0.000
D73.5 Infarction of spleen
0.000 0.477 0.523
K90 Intestinal malabsorption
0.000 0.478 0.522
M08.0 Juvenile rheumatoid arthritis
0.521 0.479 0.000
M05.18 Rheumatoid lung disease (Other)
0.521 0.479 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.521 0.479 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.521 0.479 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.521 0.479 0.000
M05.14 Rheumatoid lung disease (Hand)
0.521 0.479 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.521 0.479 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.521 0.479 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.521 0.479 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.521 0.479 0.000
M08.9 Juvenile arthritis, unspecified
0.521 0.479 0.000
M08.8 Other juvenile arthritis
0.521 0.479 0.000
M08.4 Pauciarticular juvenile arthritis
0.521 0.479 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.521 0.479 0.000
M08.1 Juvenile ankylosing spondylitis
0.521 0.479 0.000
D73.8 Other diseases of spleen
0.000 0.479 0.521
D89.3 Immune reconstitution syndrome
0.000 0.479 0.520
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.481 0.519
D58 Other hereditary haemolytic anaemias
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.514 0.486 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.488 0.512
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.488 0.512
D84.9 Immunodeficiency, unspecified
0.000 0.488 0.512
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.511 0.489 0.000
E07 Other disorders of thyroid
0.000 0.490 0.510
M05.09 Felty's syndrome (Site unspecified)
0.508 0.491 0.000
M05.08 Felty's syndrome (Other)
0.508 0.491 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.508 0.491 0.000
M05.06 Felty's syndrome (Lower leg)
0.508 0.491 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.508 0.491 0.000
M05.04 Felty's syndrome (Hand)
0.508 0.491 0.000
M05.03 Felty's syndrome (Forearm)
0.508 0.491 0.000
M05.02 Felty's syndrome (Upper arm)
0.508 0.491 0.000
M05.01 Felty's syndrome (Shoulder region)
0.508 0.491 0.000
M05.00 Felty's syndrome (Multiple sites)
0.508 0.491 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.508 0.491 0.000
M05.28 Rheumatoid vasculitis (Other)
0.508 0.491 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.508 0.491 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.508 0.491 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.508 0.491 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.508 0.491 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.508 0.491 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.508 0.491 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.508 0.491 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.508 0.491 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.508 0.491 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.508 0.491 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.508 0.491 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.508 0.491 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.508 0.491 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.508 0.491 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.508 0.491 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.508 0.491 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.508 0.491 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.508 0.491 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.507 0.492 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.507 0.492 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.507 0.492 0.000
M09.0 Juvenile arthritis in psoriasis
0.507 0.492 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.505 0.495 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.505 0.495 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.505 0.495 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.505 0.495 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.505 0.495 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.505 0.495 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.505 0.495 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.505 0.495 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.505 0.495 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.500 0.499 0.000
D57 Sickle-cell disorders
0.000 0.499 0.500
M14.6 Neuropathic arthropathy
0.500 0.500 0.000
D68.6 Other Thrombophilia
0.000 0.503 0.497
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.504 0.496
E06.1 Subacute thyroiditis
0.000 0.504 0.495
D82 Immunodeficiency associated with other major defects
0.000 0.506 0.494
M14.2 Diabetic arthropathy
0.493 0.507 0.000
D64.4 Congenital dyserythropoietic anaemia
0.000 0.508 0.492
D64.3 Other sideroblastic anaemias
0.000 0.508 0.492
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.508 0.492
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.508 0.492
D64.0 Hereditary sideroblastic anaemia
0.000 0.508 0.492
D55 Anaemia due to enzyme disorders
0.000 0.509 0.490
D84.1 Defects in the complement system
0.000 0.511 0.489
D83.9 Common variable immunodeficiency, unspecified
0.000 0.511 0.489
D73.3 Abscess of spleen
0.000 0.512 0.488
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.513 0.487
D68.0 Von Willebrand's disease
0.000 0.516 0.484
M11 Other crystal arthropathies
0.482 0.518 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.480 0.520 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.480 0.520 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.480 0.520 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.480 0.520 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.480 0.520 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.480 0.520 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.480 0.520 0.000
M10 Gout
0.478 0.522 0.000
D73.4 Cyst of spleen
0.000 0.525 0.475
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.526 0.473
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.526 0.473
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.526 0.473
M12.24 Villonodular synovitis (pigmented) (Hand)
0.473 0.527 0.000
D75.0 Familial erythrocytosis
0.000 0.531 0.469
D59.1 Other autoimmune haemolytic anaemias
0.000 0.535 0.465
M07 Psoriatic and enteropathic arthropathies
0.425 0.540 0.036
D68.9 Coagulation defect, unspecified
0.000 0.540 0.459
M06.46 Inflammatory polyarthropathy (Lower leg)
0.459 0.541 0.000
D73.2 Chronic congestive splenomegaly
0.000 0.542 0.458
M12.57 Traumatic arthropathy (Ankle and foot)
0.456 0.543 0.000
D73.9 Disease of spleen, unspecified
0.000 0.544 0.456
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.545 0.455
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.551 0.449
D83.8 Other common variable immunodeficiencies
0.000 0.553 0.447
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.553 0.447
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.553 0.447
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.553 0.447
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.554 0.446
E04 Other non-toxic goitre
0.000 0.555 0.445
D68.1 Hereditary factor XI deficiency
0.000 0.558 0.442
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.559 0.441
D69.0 Allergic purpura
0.000 0.565 0.435
D74.9 Methaemoglobinaemia, unspecified
0.000 0.565 0.435
D74.8 Other methaemoglobinaemias
0.000 0.565 0.435
D74.0 Congenital methaemoglobinaemia
0.000 0.565 0.435
D86.1 Sarcoidosis of lymph nodes
0.000 0.567 0.433
D73.1 Hypersplenism
0.000 0.569 0.430
D59.8 Other acquired haemolytic anaemias
0.000 0.573 0.427
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.573 0.427
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.573 0.427
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.573 0.427
D59.3 Haemolytic-uraemic syndrome
0.000 0.573 0.427
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.573 0.427
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.573 0.427
D50-D53 Nutritional anaemias
0.000 0.575 0.425
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.424 0.575 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.424 0.575 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.424 0.575 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.424 0.575 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.424 0.575 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.424 0.575 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.424 0.575 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.424 0.575 0.000
M12.59 Traumatic arthropathy (Site unspecified)
0.423 0.576 0.000
M12.58 Traumatic arthropathy (Other)
0.423 0.576 0.000
M12.56 Traumatic arthropathy (Lower leg)
0.423 0.576 0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.423 0.576 0.000
M12.54 Traumatic arthropathy (Hand)
0.423 0.576 0.000
M12.53 Traumatic arthropathy (Forearm)
0.423 0.576 0.000
M12.52 Traumatic arthropathy (Upper arm)
0.423 0.576 0.000
M12.51 Traumatic arthropathy (Shoulder region)
0.423 0.576 0.000
M12.50 Traumatic arthropathy (Multiple sites)
0.423 0.576 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.577 0.423
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.577 0.423
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.577 0.423
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.577 0.423
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.577 0.422
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.578 0.421
M12.30 Palindromic rheumatism (Multiple sites)
0.419 0.581 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.584 0.416
D81.8 Other combined immunodeficiencies
0.000 0.584 0.416
D81.7 Major histocompatibility complex class II deficiency
0.000 0.584 0.416
D81.6 Major histocompatibility complex class I deficiency
0.000 0.584 0.416
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.584 0.416
D81.4 Nezelof's syndrome
0.000 0.584 0.416
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.584 0.416
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.584 0.416
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.584 0.416
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.584 0.416
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.416 0.584 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.413 0.587 0.000
D84.8 Other specified immunodeficiencies
0.000 0.590 0.410
M12.39 Palindromic rheumatism (Site unspecified)
0.409 0.591 0.000
M12.38 Palindromic rheumatism (Other)
0.408 0.591 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.408 0.591 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.408 0.591 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.408 0.591 0.000
M12.34 Palindromic rheumatism (Hand)
0.408 0.591 0.000
M12.33 Palindromic rheumatism (Forearm)
0.408 0.591 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.408 0.591 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.408 0.591 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.592 0.408
D63.0 Anaemia in neoplastic disease
0.000 0.595 0.405
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.405 0.595 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.404 0.595 0.000
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)
0.400 0.600 0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)
0.400 0.600 0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)
0.400 0.600 0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)
0.400 0.600 0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)
0.400 0.600 0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)
0.400 0.600 0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)
0.400 0.600 0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)
0.400 0.600 0.000
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)
0.400 0.600 0.000
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)
0.400 0.600 0.000
M12.19 Kaschin-Beck disease (Site unspecified)
0.400 0.600 0.000
M12.18 Kaschin-Beck disease (Other)
0.400 0.600 0.000
M12.17 Kaschin-Beck disease (Ankle and foot)
0.400 0.600 0.000
M12.16 Kaschin-Beck disease (Lower leg)
0.400 0.600 0.000
M12.15 Kaschin-Beck disease (Pelvic region and thigh)
0.400 0.600 0.000
M12.14 Kaschin-Beck disease (Hand)
0.400 0.600 0.000
M12.13 Kaschin-Beck disease (Forearm)
0.400 0.600 0.000
M12.12 Kaschin-Beck disease (Upper arm)
0.400 0.600 0.000
M12.11 Kaschin-Beck disease (Shoulder region)
0.400 0.600 0.000
M12.10 Kaschin-Beck disease (Multiple sites)
0.400 0.600 0.000
M12.49 Intermittent hydrarthrosis (Site unspecified)
0.400 0.600 0.000
M12.48 Intermittent hydrarthrosis (Other)
0.400 0.600 0.000
M12.47 Intermittent hydrarthrosis (Ankle and foot)
0.400 0.600 0.000
M12.46 Intermittent hydrarthrosis (Lower leg)
0.400 0.600 0.000
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)
0.400 0.600 0.000
M12.44 Intermittent hydrarthrosis (Hand)
0.400 0.600 0.000
M12.43 Intermittent hydrarthrosis (Forearm)
0.400 0.600 0.000
M12.42 Intermittent hydrarthrosis (Upper arm)
0.400 0.600 0.000
M12.41 Intermittent hydrarthrosis (Shoulder region)
0.400 0.600 0.000
M12.40 Intermittent hydrarthrosis (Multiple sites)
0.400 0.600 0.000
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)
0.400 0.600 0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.400 0.600 0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)
0.400 0.600 0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)
0.400 0.600 0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)
0.400 0.600 0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)
0.400 0.600 0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)
0.400 0.600 0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)
0.400 0.600 0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)
0.400 0.600 0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)
0.400 0.600 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.394 0.605 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.610 0.390
M08.28 Juvenile arthritis with systemic onset (Other)
0.386 0.613 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.386 0.613 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.386 0.613 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.386 0.613 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.386 0.613 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.386 0.613 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.386 0.613 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.386 0.613 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.386 0.613 0.000
D58.0 Hereditary spherocytosis
0.000 0.619 0.381
D62 Acute posthaemorrhagic anaemia
0.000 0.621 0.379
M13 Other arthritis
0.378 0.622 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.623 0.377
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.624 0.376
D56 Thalassaemia
0.000 0.624 0.375
K90.3 Pancreatic steatorrhoea
0.000 0.625 0.375
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.625 0.375
K90.1 Tropical sprue
0.000 0.625 0.375
D58.2 Other haemoglobinopathies
0.000 0.625 0.374
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.374 0.626 0.000
E07.8 Other specified disorders of thyroid
0.000 0.626 0.374
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.374 0.626 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.374 0.626 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.374 0.626 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.374 0.626 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.374 0.626 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.374 0.626 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.374 0.626 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.374 0.626 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.374 0.626 0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.373 0.626 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.373 0.626 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.373 0.626 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.373 0.626 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.373 0.626 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.373 0.626 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.373 0.626 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.373 0.626 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.373 0.626 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.373 0.626 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.373 0.626 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.373 0.626 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.373 0.626 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.373 0.626 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.373 0.626 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.373 0.626 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.373 0.626 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.373 0.626 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.373 0.626 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.373 0.626 0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.373 0.626 0.000
M08.48 Pauciarticular juvenile arthritis (Other)
0.373 0.626 0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.373 0.626 0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.373 0.626 0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.373 0.626 0.000
M08.44 Pauciarticular juvenile arthritis (Hand)
0.373 0.626 0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.373 0.626 0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.373 0.626 0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)
0.373 0.626 0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)
0.373 0.626 0.000
M08.89 Other juvenile arthritis (Site unspecified)
0.373 0.626 0.000
M08.88 Other juvenile arthritis (Other)
0.373 0.626 0.000
M08.87 Other juvenile arthritis (Ankle and foot)
0.373 0.626 0.000
M08.86 Other juvenile arthritis (Lower leg)
0.373 0.626 0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)
0.373 0.626 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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