TreeWAS – Variant ID: rs5370

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.1 Subjective visual disturbances	0.068	0.932	0.000
H53 Visual disturbances	0.046	0.954	0.000
H53.8 Other visual disturbances	0.042	0.958	0.000
H53.2 Diplopia	0.036	0.964	0.000
H53.0 Amblyopia ex anopsia	0.036	0.964	0.000
H53.4 Visual field defects	0.035	0.965	0.000
H53.6 Night blindness	0.033	0.966	0.000
H53.5 Colour vision deficiencies	0.033	0.966	0.000
H53.3 Other disorders of binocular vision	0.033	0.966	0.000
H53.9 Visual disturbance, unspecified	0.021	0.979	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.984	0.016
S92 Fracture of foot, except ankle	0.000	0.986	0.014
S92.0 Fracture of calcaneus	0.000	0.987	0.013
S92.00 Fracture of calcaneus (closed)	0.000	0.987	0.013
S92.5 Fracture of other toe	0.000	0.987	0.013
S92.1 Fracture of talus	0.000	0.987	0.013
S92.3 Fracture of metatarsal bone	0.000	0.988	0.012
S92.50 Fracture of other toe (closed)	0.000	0.988	0.012
K14.0 Glossitis	0.012	0.988	0.000
S92.7 Multiple fractures of foot	0.000	0.988	0.012
S92.4 Fracture of great toe	0.000	0.988	0.012
S92.10 Fracture of talus (closed)	0.000	0.988	0.012
Q61.3 Polycystic kidney, unspecified	0.011	0.989	0.000
Q61.2 Polycystic kidney, adult type	0.011	0.989	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.989	0.011
H53-H54 Visual disturbances and blindness	0.011	0.989	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.989	0.011
S92.2 Fracture of other tarsal bone(s)	0.000	0.989	0.011
S92.70 Multiple fractures of foot (closed)	0.000	0.989	0.010
S92.9 Fracture of foot, unspecified	0.000	0.990	0.010
Q61 Cystic kidney disease	0.010	0.990	0.000
S92.41 Fracture of great toe (open)	0.000	0.990	0.010
M25.57 Pain in joint (Ankle and foot)	0.000	0.990	0.010
O63.9 Long labour, unspecified	0.000	0.990	0.010
S92.01 Fracture of calcaneus (open)	0.000	0.990	0.010
N50.1 Vascular disorders of male genital organs	0.000	0.990	0.010
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.991	0.009
O63 Long labour	0.000	0.991	0.009
S92.11 Fracture of talus (open)	0.000	0.991	0.009
S92.31 Fracture of metatarsal bone (open)	0.000	0.991	0.009
S92.71 Multiple fractures of foot (open)	0.000	0.991	0.009
S92.40 Fracture of great toe (closed)	0.000	0.991	0.009
Q61.9 Cystic kidney disease, unspecified	0.008	0.991	0.000
S92.51 Fracture of other toe (open)	0.000	0.992	0.008
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.992	0.008
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.992	0.008
S92.91 Fracture of foot, unspecified (open)	0.000	0.992	0.008
S92.90 Fracture of foot, unspecified (closed)	0.000	0.992	0.008
Q61.8 Other cystic kidney diseases	0.007	0.992	0.000
Q61.4 Renal dysplasia	0.007	0.992	0.000
Q61.1 Polycystic kidney, infantile type	0.007	0.992	0.000
N81.5 Vaginal enterocele	0.000	0.993	0.007
Q61.0 Congenital single renal cyst	0.007	0.993	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.007	0.993	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.993	0.007
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.993	0.007
S90-S99 Injuries to the ankle and foot	0.000	0.993	0.007
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.993	0.007
C04 Malignant neoplasm of floor of mouth	0.007	0.993	0.000
S42.3 Fracture of shaft of humerus	0.000	0.993	0.007
S90 Superficial injury of ankle and foot	0.000	0.993	0.007
Q61.5 Medullary cystic kidney	0.006	0.994	0.000
C09 Malignant neoplasm of tonsil	0.006	0.994	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.994	0.006
C02 Malignant neoplasm of other and unspecified parts of tongue	0.006	0.994	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.006	0.994	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.006	0.994	0.000
C11 Malignant neoplasm of nasopharynx	0.006	0.994	0.000
C04.0 Anterior floor of mouth	0.006	0.994	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.994	0.006
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.994	0.006
C01 Malignant neoplasm of base of tongue	0.006	0.994	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.006	0.994	0.000
C12 Malignant neoplasm of pyriform sinus	0.006	0.994	0.000
S91 Open wound of ankle and foot	0.000	0.994	0.006
C13 Malignant neoplasm of hypopharynx	0.006	0.994	0.000
C10 Malignant neoplasm of oropharynx	0.006	0.994	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.006	0.994	0.000
C14.0 Pharynx, unspecified	0.006	0.994	0.000
C07 Malignant neoplasm of parotid gland	0.006	0.994	0.000
S91.3 Open wound of other parts of foot	0.000	0.994	0.006
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.994	0.006
C04.9 Floor of mouth, unspecified	0.005	0.994	0.000
C03 Malignant neoplasm of gum	0.005	0.995	0.000
C00 Malignant neoplasm of lip	0.005	0.995	0.000
I08.0 Disorders of both mitral and aortic valves	0.005	0.995	0.000
C02.9 Tongue, unspecified	0.005	0.995	0.000
C11.9 Nasopharynx, unspecified	0.005	0.995	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.995	0.005
S95 Injury of blood vessels at ankle and foot level	0.000	0.995	0.005
S94 Injury of nerves at ankle and foot level	0.000	0.995	0.005
C06.9 Mouth, unspecified	0.005	0.995	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.995	0.005
R40.2 Coma, unspecified	0.000	0.995	0.005
C02.1 Border of tongue	0.005	0.995	0.000
R23.8 Other and unspecified skin changes	0.005	0.995	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.995	0.005
C04.8 Overlapping lesion of floor of mouth	0.005	0.995	0.000
C04.1 Lateral floor of mouth	0.005	0.995	0.000
C05 Malignant neoplasm of palate	0.005	0.995	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.995	0.005
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.995	0.005
S90.2 Contusion of toe(s) with damage to nail	0.000	0.995	0.005
S90.1 Contusion of toe(s) without damage to nail	0.000	0.995	0.005
C02.4 Lingual tonsil	0.005	0.995	0.000
S91.0 Open wound of ankle	0.000	0.995	0.005
S90.3 Contusion of other and unspecified parts of foot	0.000	0.995	0.005
C09.8 Overlapping lesion of tonsil	0.005	0.995	0.000
C09.0 Tonsillar fossa	0.005	0.995	0.000
C02.8 Overlapping lesion of tongue	0.005	0.995	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.005	0.995	0.000
C02.2 Ventral surface of tongue	0.005	0.995	0.000
C02.0 Dorsal surface of tongue	0.005	0.995	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.005	0.995	0.000
C14.2 Waldeyer's ring	0.005	0.995	0.000
C06.0 Cheek mucosa	0.005	0.995	0.000
O70.1 Second degree perineal laceration during delivery	0.000	0.995	0.005
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.995	0.005
S99 Other and unspecified injuries of ankle and foot	0.000	0.995	0.005
C10.9 Oropharynx, unspecified	0.005	0.995	0.000
C13.9 Hypopharynx, unspecified	0.004	0.995	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.995	0.005
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.004	0.995	0.000
C06.1 Vestibule of mouth	0.004	0.995	0.000
S97 Crushing injury of ankle and foot	0.000	0.995	0.004
C11.8 Overlapping lesion of nasopharynx	0.004	0.995	0.000
C11.3 Anterior wall of nasopharynx	0.004	0.995	0.000
C11.2 Lateral wall of nasopharynx	0.004	0.995	0.000
C11.1 Posterior wall of nasopharynx	0.004	0.995	0.000
C11.0 Superior wall of nasopharynx	0.004	0.995	0.000
C09.9 Tonsil, unspecified	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.005	0.995	0.000
C06.2 Retromolar area	0.004	0.995	0.000
C08.9 Major salivary gland, unspecified	0.004	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.996	0.004
C10.8 Overlapping lesion of oropharynx	0.004	0.996	0.000
C10.4 Branchial cleft	0.004	0.996	0.000
C10.3 Posterior wall of oropharynx	0.004	0.996	0.000
C10.2 Lateral wall of oropharynx	0.004	0.996	0.000
C10.1 Anterior surface of epiglottis	0.004	0.996	0.000
C10.0 Vallecula	0.004	0.996	0.000
C13.8 Overlapping lesion of hypopharynx	0.004	0.996	0.000
C13.2 Posterior wall of hypopharynx	0.004	0.996	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.004	0.996	0.000
C13.0 Postcricoid region	0.004	0.996	0.000
C08.8 Overlapping lesion of major salivary glands	0.004	0.996	0.000
C08.1 Sublingual gland	0.004	0.996	0.000
C08.0 Submandibular gland	0.004	0.996	0.000
I08 Multiple valve diseases	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.996	0.004
C00.9 Lip, unspecified	0.004	0.996	0.000
C00.8 Overlapping lesion of lip	0.004	0.996	0.000
C00.6 Commissure of lip	0.004	0.996	0.000
C00.5 Lip, unspecified, inner aspect	0.004	0.996	0.000
C00.4 Lower lip, inner aspect	0.004	0.996	0.000
C00.3 Upper lip, inner aspect	0.004	0.996	0.000
C00.2 External lip, unspecified	0.004	0.996	0.000
C00.1 External lower lip	0.004	0.996	0.000
C00.0 External upper lip	0.004	0.996	0.000
C03.9 Gum, unspecified	0.004	0.996	0.000
C03.1 Lower gum	0.004	0.996	0.000
C03.0 Upper gum	0.004	0.996	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.996	0.004
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.996	0.004
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.996	0.004
S94.8 Injury of other nerves at ankle and foot level	0.000	0.996	0.004
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.996	0.004
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.996	0.004
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.996	0.004
S94.1 Injury of medial plantar nerve	0.000	0.996	0.004
S94.0 Injury of lateral plantar nerve	0.000	0.996	0.004
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.996	0.004
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.996	0.004
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.996	0.004
S95.2 Injury of dorsal vein of foot	0.000	0.996	0.004
S95.1 Injury of plantar artery of foot	0.000	0.996	0.004
S95.0 Injury of dorsal artery of foot	0.000	0.996	0.004
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.996	0.004
S98.3 Traumatic amputation of other parts of foot	0.000	0.996	0.004
S98.2 Traumatic amputation of two or more toes	0.000	0.996	0.004
S98.1 Traumatic amputation of one toe	0.000	0.996	0.004
S98.0 Traumatic amputation of foot at ankle level	0.000	0.996	0.004
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.996	0.004
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.996	0.004
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.996	0.004
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.996	0.004
S90.0 Contusion of ankle	0.000	0.996	0.004
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
C05.8 Overlapping lesion of palate	0.004	0.996	0.000
C05.2 Uvula	0.004	0.996	0.000
C05.0 Hard palate	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.996	0.004
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.996	0.004
C05.1 Soft palate	0.004	0.996	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.996	0.004
I08.8 Other multiple valve diseases	0.004	0.996	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.996	0.004
S99.7 Multiple injuries of ankle and foot	0.000	0.996	0.003
C05.9 Palate, unspecified	0.003	0.996	0.000
S97.1 Crushing injury of toe(s)	0.000	0.996	0.003
S97.0 Crushing injury of ankle	0.000	0.996	0.003
S42 Fracture of shoulder and upper arm	0.000	0.996	0.004
I08.9 Multiple valve disease, unspecified	0.003	0.996	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.996	0.003
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.996	0.004
S42.2 Fracture of upper end of humerus	0.000	0.997	0.003
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
H54 Blindness and low vision	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.997	0.003
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.997	0.003
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.997	0.003
F31.9 Bipolar affective disorder, unspecified	0.000	0.997	0.003
H54.5 Low vision, one eye	0.003	0.997	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.997	0.003
B37.9 Candidiasis, unspecified	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.003	0.997	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.003	0.997	0.000
R40 Somnolence, stupor and coma	0.000	0.997	0.003
S61.7 Multiple open wounds of wrist and hand	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.997	0.003
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.997	0.003
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
S93.4 Sprain and strain of ankle	0.000	0.997	0.003
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.997	0.003
S93.5 Sprain and strain of toe(s)	0.000	0.997	0.003
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.997	0.003
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.997	0.003
H54.2 Low vision, both eyes	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.997	0.003
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.997	0.003
H54.3 Unqualified visual loss, both eyes	0.003	0.997	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.997	0.003
Q64.9 Congenital malformation of urinary system, unspecified	0.003	0.997	0.000
Q64.8 Other specified congenital malformations of urinary system	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.003	0.997	0.000
Q64.6 Congenital diverticulum of bladder	0.003	0.997	0.000
Q64.5 Congenital absence of bladder and urethra	0.003	0.997	0.000
Q64.4 Malformation of urachus	0.003	0.997	0.000
Q64.2 Congenital posterior urethral valves	0.003	0.997	0.000
Q64.1 Exstrophy of urinary bladder	0.003	0.997	0.000
Q64.0 Epispadias	0.003	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.997	0.003
Y84.6 Urinary catheterisation	0.000	0.997	0.003
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.997	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.003
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.003
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.997	0.002
R40.0 Somnolence	0.000	0.997	0.003
S42.1 Fracture of scapula	0.000	0.997	0.003
S93.0 Dislocation of ankle joint	0.000	0.997	0.002
R40.1 Stupor	0.000	0.997	0.003
N84.1 Polyp of cervix uteri	0.000	0.997	0.003
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.003	0.997	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.997	0.002
K31.8 Other specified diseases of stomach and duodenum	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.002	0.997	0.000
M25.53 Pain in joint (Forearm)	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
Q03 Congenital hydrocephalus	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.998	0.002
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
S42.11 Fracture of scapula (open)	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.998	0.002
Q78.2 Osteopetrosis	0.002	0.998	0.000
S01.0 Open wound of scalp	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Q17.5 Prominent ear	0.002	0.998	0.000
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
C48.2 Peritoneum, unspecified	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
Q60.6 Potter's syndrome	0.001	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
N50 Other disorders of male genital organs	0.000	0.998	0.002
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.998	0.001
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.998	0.002
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
C48.1 Specified parts of peritoneum	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.998	0.001
M10.90 Gout, unspecified (Multiple sites)	0.002	0.998	0.000
N84.2 Polyp of vagina	0.000	0.998	0.002
Q39.4 Oesophageal web	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.001	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.001	0.998	0.000
R44.3 Hallucinations, unspecified	0.000	0.998	0.002
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.998	0.002
Q39.9 Congenital malformation of oesophagus, unspecified	0.001	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.001	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.001	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.001	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.001	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.001	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.001	0.998	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.002	0.998	0.000
N84.0 Polyp of corpus uteri	0.000	0.998	0.002
Q17.9 Congenital malformation of ear, unspecified	0.001	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.001	0.998	0.000
Q17.4 Misplaced ear	0.001	0.998	0.000
Q17.3 Other misshapen ear	0.001	0.998	0.000
Q17.2 Microtia	0.001	0.998	0.000
Q17.1 Macrotia	0.001	0.998	0.000
Q17.0 Accessory auricle	0.001	0.998	0.000
T51.0 Ethanol	0.002	0.998	0.000
N72 Inflammatory disease of cervix uteri	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.002
N50.0 Atrophy of testis	0.000	0.998	0.002
Q15.0 Congenital glaucoma	0.001	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.001	0.998	0.000
Q67.5 Congenital deformity of spine	0.001	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
F20.8 Other schizophrenia	0.000	0.998	0.001
F20.6 Simple schizophrenia	0.000	0.998	0.001
F20.4 Postschizophrenic depression	0.000	0.998	0.001
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.001
F20.2 Catatonic schizophrenia	0.000	0.998	0.001
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.001
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.001	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.001	0.998	0.000
Q33 Congenital malformations of lung	0.001	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
Q31.0 Web of larynx	0.001	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
I09 Other rheumatic heart diseases	0.001	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.001	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.001	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations