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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72661820
log Bayes Factor = 16.7411
Chromosome 13   position 112,504,318  (GRCh37) Explore rs72661820 on Ensembl!
Variant rs72661820 is part of Cluster X0029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
N20-N23 Urolithiasis
1.000 0.000 0.000
N20 Calculus of kidney and ureter
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
N20.0 Calculus of kidney
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
N17-N19 Renal failure
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
J40-J47 Chronic lower respiratory diseases
0.988 0.012 0.000
C15-C26 Malignant neoplasms of digestive organs
0.987 0.013 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.978 0.022 0.000
J90-J94 Other diseases of pleura
0.977 0.023 0.000
N10-N16 Renal tubulo-interstitial diseases
0.970 0.030 0.000
J09-J18 Influenza and pneumonia
0.966 0.034 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.964 0.036 0.000
N20.1 Calculus of ureter
0.962 0.038 0.000
Chapter I Certain infectious and parasitic diseases
0.961 0.039 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.960 0.040 0.000
J90 Pleural effusion, not elsewhere classified
0.958 0.042 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.957 0.043 0.000
N30-N39 Other diseases of urinary system
0.955 0.045 0.000
N18 Chronic renal failure
0.953 0.047 0.000
N17 Acute renal failure
0.951 0.049 0.000
M20-M25 Other joint disorders
0.949 0.051 0.000
J45 Asthma
0.946 0.054 0.000
B95-B98 Bacterial, viral and other infectious agents
0.946 0.054 0.000
N13 Obstructive and reflux uropathy
0.945 0.055 0.000
N60-N64 Disorders of breast
0.944 0.056 0.000
M25 Other joint disorders, not elsewhere classified
0.944 0.056 0.000
N32 Other disorders of bladder
0.924 0.076 0.000
J18 Pneumonia, organism unspecified
0.923 0.077 0.000
N17.9 Acute renal failure, unspecified
0.919 0.081 0.000
J47 Bronchiectasis
0.918 0.082 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.914 0.086 0.000
J45.9 Asthma, unspecified
0.913 0.087 0.000
M25.5 Pain in joint
0.913 0.087 0.000
G30-G32 Other degenerative diseases of the nervous system
0.913 0.087 0.000
Chapter IX Diseases of the circulatory system
0.911 0.089 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.910 0.090 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.908 0.092 0.000
J18.9 Pneumonia, unspecified
0.904 0.096 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.903 0.097 0.000
E00-E07 Disorders of thyroid gland
0.897 0.103 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.896 0.104 0.000
Chapter VII Diseases of the eye and adnexa
0.895 0.105 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.890 0.110 0.000
S80-S89 Injuries to the knee and lower leg
0.888 0.112 0.000
N19 Unspecified renal failure
0.888 0.112 0.000
E20-E35 Disorders of other endocrine glands
0.888 0.112 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.884 0.116 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.881 0.119 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.880 0.120 0.000
J60-J70 Lung diseases due to external agents
0.879 0.121 0.000
G90-G99 Other disorders of the nervous system
0.879 0.121 0.000
S20-S29 Injuries to the thorax
0.879 0.121 0.000
N20.2 Calculus of kidney with calculus of ureter
0.878 0.122 0.000
N32.8 Other specified disorders of bladder
0.877 0.123 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.874 0.126 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.872 0.128 0.000
C20 Malignant neoplasm of rectum
0.871 0.129 0.000
Y83.9 Surgical procedure, unspecified
0.870 0.130 0.000
D00-D09 In situ neoplasms
0.865 0.135 0.000
N00-N08 Glomerular diseases
0.859 0.141 0.000
W00-W19 Falls
0.859 0.141 0.000
E70-E90 Metabolic disorders
0.856 0.144 0.000
E05.9 Thyrotoxicosis, unspecified
0.854 0.146 0.000
G20-G26 Extrapyramidal and movement disorders
0.853 0.147 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.853 0.147 0.000
J42 Unspecified chronic bronchitis
0.851 0.149 0.000
N63 Unspecified lump in breast
0.849 0.151 0.000
J00-J06 Acute upper respiratory infections
0.849 0.151 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.845 0.155 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.844 0.156 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.834 0.166 0.000
M91-M94 Chondropathies
0.833 0.167 0.000
C90.0 Multiple myeloma
0.833 0.167 0.000
N18.9 Chronic renal failure, unspecified
0.832 0.168 0.000
N18.5 Chronic kidney disease, stage 5
0.829 0.171 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.829 0.171 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.829 0.171 0.000
H53-H54 Visual disturbances and blindness
0.829 0.171 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.828 0.172 0.000
C18 Malignant neoplasm of colon
0.827 0.172 0.000
J20-J22 Other acute lower respiratory infections
0.825 0.175 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.820 0.180 0.000
M25.8 Other specified joint disorders
0.814 0.186 0.000
C16 Malignant neoplasm of stomach
0.812 0.188 0.000
S40-S49 Injuries to the shoulder and upper arm
0.810 0.190 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.810 0.190 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.808 0.192 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.808 0.192 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.807 0.193 0.000
M25.7 Osteophyte
0.806 0.194 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.804 0.196 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.799 0.201 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.798 0.202 0.000
N18.4 Chronic kidney disease, stage 4
0.798 0.202 0.000
N13.3 Other and unspecified hydronephrosis
0.798 0.202 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.797 0.203 0.000
S00-S09 Injuries to the head
0.797 0.203 0.000
Chapter XXII Codes for special purposes
0.794 0.206 0.000
J69 Pneumonitis due to solids and liquids
0.793 0.207 0.000
S70-S79 Injuries to the hip and thigh
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
C15 Malignant neoplasm of oesophagus
0.790 0.210 0.000
S50-S59 Injuries to the elbow and forearm
0.787 0.213 0.000
M25.4 Effusion of joint
0.786 0.214 0.000
N10 Acute tubulo-interstitial nephritis
0.785 0.215 0.000
N35 Urethral stricture
0.784 0.215 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.783 0.217 0.000
N60 Benign mammary dysplasia
0.780 0.220 0.000
M80-M85 Disorders of bone density and structure
0.775 0.225 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.774 0.226 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.774 0.226 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.773 0.227 0.000
N13.4 Hydroureter
0.773 0.227 0.000
N13.6 Pyonephrosis
0.773 0.227 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.771 0.229 0.000
S81 Open wound of lower leg
0.770 0.230 0.000
S90-S99 Injuries to the ankle and foot
0.768 0.232 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.767 0.233 0.000
D05 Carcinoma in situ of breast
0.766 0.234 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.765 0.235 0.000
A30-A49 Other bacterial diseases
0.762 0.238 0.000
V80-V89 Other land transport accidents
0.761 0.239 0.000
W19 Unspecified fall
0.760 0.240 0.000
J43 Emphysema
0.759 0.241 0.000
G30 Alzheimer's disease
0.757 0.243 0.000
N30 Cystitis
0.756 0.244 0.000
S80 Superficial injury of lower leg
0.755 0.245 0.000
R26 Abnormalities of gait and mobility
0.755 0.245 0.000
N32.3 Diverticulum of bladder
0.754 0.246 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.754 0.246 0.000
T66-T78 Other and unspecified effects of external causes
0.754 0.246 0.000
N32.9 Bladder disorder, unspecified
0.754 0.246 0.000
Y83.6 Removal of other organ (partial) (total)
0.753 0.247 0.000
J91 Pleural effusion in conditions classified elsewhere
0.752 0.248 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.751 0.249 0.000
J95-J99 Other diseases of the respiratory system
0.749 0.251 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.746 0.254 0.000
N36 Other disorders of urethra
0.745 0.255 0.000
H53 Visual disturbances
0.745 0.255 0.000
I05-I09 Chronic rheumatic heart diseases
0.745 0.255 0.000
T79-T79 Certain early complications of trauma
0.744 0.256 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.744 0.256 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.744 0.256 0.000
J02 Acute pharyngitis
0.743 0.257 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.742 0.258 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.742 0.258 0.000
I73 Other peripheral vascular diseases
0.742 0.258 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.742 0.258 0.000
Chapter VIII Diseases of the ear and mastoid process
0.741 0.259 0.000
J93 Pneumothorax
0.741 0.259 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.740 0.260 0.000
N21 Calculus of lower urinary tract
0.740 0.260 0.000
N25-N29 Other disorders of kidney and ureter
0.740 0.260 0.000
M20 Acquired deformities of fingers and toes
0.740 0.260 0.000
E21.3 Hyperparathyroidism, unspecified
0.737 0.263 0.000
M25.53 Pain in joint (Forearm)
0.736 0.264 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.736 0.264 0.000
G20 Parkinson's disease
0.735 0.265 0.000
D10-D36 Benign neoplasms
0.735 0.265 0.000
M25.50 Pain in joint (Multiple sites)
0.734 0.266 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.733 0.267 0.000
E87.7 Fluid overload
0.732 0.268 0.000
J69.0 Pneumonitis due to food and vomit
0.731 0.269 0.000
H55-H59 Other disorders of eye and adnexa
0.730 0.270 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
W20-W49 Exposure to inanimate mechanical forces
0.729 0.271 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.728 0.272 0.000
N64 Other disorders of breast
0.727 0.273 0.000
M15-M19 Arthrosis
0.727 0.273 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.727 0.273 0.000
G93 Other disorders of brain
0.727 0.273 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.726 0.274 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.725 0.275 0.000
I71 Aortic aneurysm and dissection
0.724 0.276 0.000
G96 Other disorders of central nervous system
0.724 0.276 0.000
Y52 Agents primarily affecting the cardiovascular system
0.723 0.277 0.000
M93 Other osteochondropathies
0.721 0.278 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.721 0.279 0.000
C25 Malignant neoplasm of pancreas
0.719 0.281 0.000
C18.7 Sigmoid colon
0.718 0.282 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.717 0.283 0.000
N20.9 Urinary calculus, unspecified
0.717 0.283 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.717 0.283 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.717 0.283 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
N18.0 End-stage renal disease
0.714 0.286 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.711 0.289 0.000
N62 Hypertrophy of breast
0.710 0.290 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.710 0.290 0.000
M23 Internal derangement of knee
0.710 0.290 0.000
J41 Simple and mucopurulent chronic bronchitis
0.708 0.292 0.000
J46 Status asthmaticus
0.708 0.292 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.708 0.292 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.708 0.292 0.000
C21 Malignant neoplasm of anus and anal canal
0.708 0.292 0.000
C17 Malignant neoplasm of small intestine
0.708 0.292 0.000
C23 Malignant neoplasm of gallbladder
0.708 0.292 0.000
Y95 Nosocomial condition
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.707 0.293 0.000
I60-I69 Cerebrovascular diseases
0.707 0.293 0.000
X60-X84 Intentional self-harm
0.706 0.293 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.706 0.294 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.705 0.294 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.705 0.295 0.000
C95 Leukaemia of unspecified cell type
0.705 0.295 0.000
C94 Other leukaemias of specified cell type
0.705 0.295 0.000
C93 Monocytic leukaemia
0.705 0.295 0.000
C92 Myeloid leukaemia
0.705 0.295 0.000
C88 Malignant immunoproliferative diseases
0.705 0.295 0.000
C86 Other specified types of T/NK-cell lymphoma
0.705 0.295 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.705 0.295 0.000
C81 Hodgkin's disease
0.705 0.295 0.000
J45.0 Predominantly allergic asthma
0.705 0.295 0.000
D05.1 Intraductal carcinoma in situ
0.705 0.295 0.000
Y43 Primarily systemic agents
0.705 0.295 0.000
H10-H13 Disorders of conjunctiva
0.704 0.296 0.000
J40 Bronchitis, not specified as acute or chronic
0.704 0.296 0.000
N13.8 Other obstructive and reflux uropathy
0.703 0.297 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.702 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.298 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.701 0.299 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
J94 Other pleural conditions
0.700 0.299 0.000
M22 Disorders of patella
0.700 0.300 0.000
J22 Unspecified acute lower respiratory infection
0.699 0.301 0.000
M25.56 Pain in joint (Lower leg)
0.697 0.303 0.000
M25.51 Pain in joint (Shoulder region)
0.697 0.303 0.000
B15-B19 Viral hepatitis
0.695 0.304 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.695 0.305 0.000
N15 Other renal tubulo-interstitial diseases
0.695 0.305 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.695 0.305 0.000
N11 Chronic tubulo-interstitial nephritis
0.695 0.305 0.000
J15.1 Pneumonia due to Pseudomonas
0.695 0.305 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.695 0.305 0.000
H54 Blindness and low vision
0.695 0.305 0.000
S60-S69 Injuries to the wrist and hand
0.693 0.307 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.693 0.307 0.000
J17 Pneumonia in diseases classified elsewhere
0.692 0.308 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.692 0.308 0.000
J12 Viral pneumonia, not elsewhere classified
0.692 0.308 0.000
J11 Influenza, virus not identified
0.692 0.308 0.000
J10 Influenza due to identified influenza virus
0.692 0.308 0.000
J14 Pneumonia due to Haemophilus influenzae
0.692 0.308 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.692 0.308 0.000
J09 Influenza due to certain identified influenza virus
0.692 0.308 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.692 0.308 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.691 0.309 0.000
E40-E46 Malnutrition
0.691 0.309 0.000
B35-B49 Mycoses
0.690 0.309 0.000
B99-B99 Other infectious diseases
0.689 0.311 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.689 0.311 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.689 0.311 0.000
B65-B83 Helminthiases
0.689 0.311 0.000
B50-B64 Protozoal diseases
0.689 0.311 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.689 0.311 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.689 0.311 0.000
A80-A89 Viral infections of the central nervous system
0.689 0.311 0.000
A75-A79 Rickettsioses
0.689 0.311 0.000
A70-A74 Other diseases caused by chlamydiae
0.689 0.311 0.000
A65-A69 Other spirochaetal diseases
0.689 0.311 0.000
A20-A28 Certain zoonotic bacterial diseases
0.689 0.311 0.000
A15-A19 Tuberculosis
0.689 0.311 0.000
H43-H45 Disorders of vitreous body and globe
0.689 0.311 0.000
N61 Inflammatory disorders of breast
0.689 0.311 0.000
M60-M63 Disorders of muscles
0.688 0.312 0.000
M00-M03 Infectious arthropathies
0.688 0.312 0.000
N99-N99 Other disorders of the genitourinary system
0.688 0.312 0.000
E87.5 Hyperkalaemia
0.688 0.312 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.687 0.313 0.000
S29 Other and unspecified injuries of thorax
0.687 0.313 0.000
R27 Other lack of coordination
0.686 0.314 0.000
M86-M90 Other osteopathies
0.686 0.314 0.000
Y83.5 Amputation of limb(s)
0.686 0.314 0.000
Y83.0 Surgical operation with transplant of whole organ
0.686 0.314 0.000
C16.0 Cardia
0.686 0.314 0.000
I30-I52 Other forms of heart disease
0.686 0.314 0.000
C83.3 Large cell (diffuse)
0.685 0.315 0.000
I84 Haemorrhoids
0.685 0.315 0.000
N37 Urethral disorders in diseases classified elsewhere
0.684 0.316 0.000
N34 Urethritis and urethral syndrome
0.684 0.316 0.000
N33 Bladder disorders in diseases classified elsewhere
0.684 0.316 0.000
E83 Disorders of mineral metabolism
0.684 0.316 0.000
E21.0 Primary hyperparathyroidism
0.684 0.316 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.683 0.317 0.000
N18.8 Other chronic renal failure
0.683 0.317 0.000
N18.2 Chronic kidney disease, stage 2
0.683 0.317 0.000
N18.1 Chronic kidney disease, stage 1
0.683 0.317 0.000
Y83.3 Surgical operation with formation of external stoma
0.683 0.317 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.682 0.318 0.000
N17.8 Other acute renal failure
0.682 0.318 0.000
N17.2 Acute renal failure with medullary necrosis
0.682 0.318 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.682 0.318 0.000
N17.0 Acute renal failure with tubular necrosis
0.682 0.318 0.000
V10-V19 Pedal cyclist injured in transport accident
0.681 0.319 0.000
S20 Superficial injury of thorax
0.681 0.319 0.000
C91 Lymphoid leukaemia
0.681 0.319 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.681 0.319 0.000
M34 Systemic sclerosis
0.681 0.319 0.000
M33 Dermatopolymyositis
0.681 0.319 0.000
M32 Systemic lupus erythematosus
0.681 0.319 0.000
M30 Polyarteritis nodosa and related conditions
0.681 0.319 0.000
M21 Other acquired deformities of limbs
0.681 0.319 0.000
S42 Fracture of shoulder and upper arm
0.680 0.320 0.000
J45.8 Mixed asthma
0.678 0.321 0.000
J45.1 Nonallergic asthma
0.678 0.321 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.677 0.323 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.677 0.323 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.677 0.323 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.677 0.323 0.000
M25.9 Joint disorder, unspecified
0.676 0.323 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.676 0.323 0.000
M25.3 Other instability of joint
0.676 0.323 0.000
M25.2 Flail joint
0.676 0.323 0.000
M25.1 Fistula of joint
0.676 0.323 0.000
M25.0 Haemarthrosis
0.676 0.323 0.000
S09 Other and unspecified injuries of head
0.676 0.324 0.000
E29 Testicular dysfunction
0.675 0.325 0.000
M25.74 Osteophyte (Hand)
0.675 0.325 0.000
M25.86 Other specified joint disorders (Lower leg)
0.675 0.325 0.000
G31.8 Other specified degenerative diseases of nervous system
0.674 0.325 0.000
M25.46 Effusion of joint (Lower leg)
0.673 0.327 0.000
J30-J39 Other diseases of upper respiratory tract
0.673 0.327 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.673 0.327 0.000
J03 Acute tonsillitis
0.673 0.327 0.000
I27 Other pulmonary heart diseases
0.672 0.328 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.671 0.329 0.000
G25 Other extrapyramidal and movement disorders
0.670 0.330 0.000
I73.0 Raynaud's syndrome
0.670 0.330 0.000
R29.6 Tendency to fall, not elsewhere classified
0.670 0.330 0.000
N03 Chronic nephritic syndrome
0.669 0.331 0.000
M25.57 Pain in joint (Ankle and foot)
0.669 0.331 0.000
N60.8 Other benign mammary dysplasias
0.669 0.331 0.000
M40-M43 Deforming dorsopathies
0.669 0.331 0.000
C18.6 Descending colon
0.669 0.331 0.000
S81.8 Open wound of other parts of lower leg
0.667 0.333 0.000
J02.9 Acute pharyngitis, unspecified
0.667 0.333 0.000
G12 Spinal muscular atrophy and related syndromes
0.667 0.333 0.000
M31 Other necrotising vasculopathies
0.666 0.334 0.000
H30-H36 Disorders of choroid and retina
0.665 0.335 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.664 0.335 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.664 0.336 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
N35.9 Urethral stricture, unspecified
0.663 0.337 0.000
N32.4 Rupture of bladder, nontraumatic
0.663 0.337 0.000
N32.2 Vesical fistula, not elsewhere classified
0.663 0.337 0.000
N32.1 Vesicointestinal fistula
0.663 0.337 0.000
E07 Other disorders of thyroid
0.662 0.338 0.000
J18.8 Other pneumonia, organism unspecified
0.662 0.338 0.000
J18.2 Hypostatic pneumonia, unspecified
0.662 0.338 0.000
C85.1 B-cell lymphoma, unspecified
0.661 0.339 0.000
C15.9 Oesophagus, unspecified
0.661 0.339 0.000
J18.0 Bronchopneumonia, unspecified
0.660 0.340 0.000
D09 Carcinoma in situ of other and unspecified sites
0.660 0.340 0.000
M25.84 Other specified joint disorders (Hand)
0.659 0.341 0.000
N04 Nephrotic syndrome
0.658 0.342 0.000
I74 Arterial embolism and thrombosis
0.656 0.343 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.655 0.345 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.655 0.345 0.000
M25.59 Pain in joint (Site unspecified)
0.655 0.345 0.000
M25.58 Pain in joint (Other)
0.655 0.345 0.000
M25.54 Pain in joint (Hand)
0.655 0.345 0.000
M25.52 Pain in joint (Upper arm)
0.655 0.345 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.654 0.346 0.000
S06 Intracranial injury
0.653 0.347 0.000
I00-I02 Acute rheumatic fever
0.653 0.347 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.652 0.348 0.000
N18.3 Chronic kidney disease, stage 3
0.652 0.348 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.651 0.349 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.651 0.349 0.000
C85.0 Lymphosarcoma
0.651 0.349 0.000
M17 Gonarthrosis [arthrosis of knee]
0.651 0.349 0.000
M24 Other specific joint derangements
0.650 0.350 0.000
E23 Hypofunction and other disorders of pituitary gland
0.650 0.350 0.000
N23 Unspecified renal colic
0.649 0.350 0.000
M25.77 Osteophyte (Ankle and foot)
0.648 0.352 0.000
T87 Complications peculiar to reattachment and amputation
0.648 0.352 0.000
T86 Failure and rejection of transplanted organs and tissues
0.648 0.352 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.648 0.352 0.000
S27 Injury of other and unspecified intrathoracic organs
0.646 0.353 0.000
I84.9 Unspecified haemorrhoids without complication
0.646 0.354 0.000
G30.9 Alzheimer's disease, unspecified
0.645 0.355 0.000
S72 Fracture of femur
0.644 0.356 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.644 0.356 0.000
E06 Thyroiditis
0.643 0.357 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.643 0.357 0.000
E00 Congenital iodine-deficiency syndrome
0.643 0.357 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.643 0.357 0.000
M94 Other disorders of cartilage
0.643 0.357 0.000
J92 Pleural plaque
0.642 0.357 0.000
C90.3 Solitary plasmacytoma
0.642 0.358 0.000
C90.2 Plasmacytoma, extramedullary
0.642 0.358 0.000
C90.1 Plasma cell leukaemia
0.642 0.358 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.642 0.358 0.000
M93.9 Osteochondropathy, unspecified
0.641 0.359 0.000
D17 Benign lipomatous neoplasm
0.641 0.359 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.640 0.360 0.000
G82 Paraplegia and tetraplegia
0.639 0.361 0.000
E88 Other metabolic disorders
0.639 0.361 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.638 0.361 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.638 0.361 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.638 0.361 0.000
N32.0 Bladder-neck obstruction
0.638 0.362 0.000
H53.2 Diplopia
0.638 0.362 0.000
D32 Benign neoplasm of meninges
0.638 0.362 0.000
S88 Traumatic amputation of lower leg
0.637 0.363 0.000
S87 Crushing injury of lower leg
0.637 0.363 0.000
S86 Injury of muscle and tendon at lower leg level
0.637 0.363 0.000
S85 Injury of blood vessels at lower leg level
0.637 0.363 0.000
S84 Injury of nerves at lower leg level
0.637 0.363 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.637 0.363 0.000
E34 Other endocrine disorders
0.637 0.363 0.000
E32 Diseases of thymus
0.637 0.363 0.000
E31 Polyglandular dysfunction
0.637 0.363 0.000
E30 Disorders of puberty, not elsewhere classified
0.637 0.363 0.000
E28 Ovarian dysfunction
0.637 0.363 0.000
E27 Other disorders of adrenal gland
0.637 0.363 0.000
E26 Hyperaldosteronism
0.637 0.363 0.000
E25 Adrenogenital disorders
0.637 0.363 0.000
E24 Cushing's syndrome
0.637 0.363 0.000
E22 Hyperfunction of pituitary gland
0.637 0.363 0.000
E20 Hypoparathyroidism
0.637 0.363 0.000
Y83.4 Other reconstructive surgery
0.636 0.364 0.000
M17.1 Other primary gonarthrosis
0.635 0.365 0.000
T92 Sequelae of injuries of upper limb
0.635 0.365 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.634 0.366 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.633 0.366 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.633 0.366 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.633 0.366 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.633 0.366 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.633 0.366 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.633 0.366 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.633 0.366 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.633 0.366 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.633 0.366 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.633 0.366 0.000
T36 Poisoning by systemic antibiotics
0.633 0.366 0.000
N02 Recurrent and persistent haematuria
0.632 0.368 0.000
Y59 Other and unspecified vaccines and biological substances
0.632 0.368 0.000
Y58 Bacterial vaccines
0.632 0.368 0.000
Y57 Other and unspecified drugs and medicaments
0.632 0.368 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.632 0.368 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.632 0.368 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.632 0.368 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.632 0.368 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.632 0.368 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.632 0.368 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
Y48 Anaesthetics and therapeutic gases
0.632 0.368 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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