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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76050622
log Bayes Factor = 12.2442
Chromosome 11   position 124,146,251  (GRCh37) Explore rs76050622 on Ensembl!
Variant rs76050622 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.992 0.008 0.000
M23 Internal derangement of knee
0.992 0.008 0.000
M15-M19 Arthrosis
0.983 0.017 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.981 0.019 0.000
M45-M49 Spondylopathies
0.981 0.019 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.979 0.021 0.000
S80-S89 Injuries to the knee and lower leg
0.969 0.031 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.962 0.038 0.000
M25 Other joint disorders, not elsewhere classified
0.955 0.045 0.000
J90-J94 Other diseases of pleura
0.949 0.051 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.948 0.052 0.000
O60-O75 Complications of labour and delivery
0.947 0.053 0.000
M23.8 Other internal derangements of knee
0.946 0.054 0.000
K08 Other disorders of teeth and supporting structures
0.944 0.056 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.943 0.057 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.939 0.061 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.936 0.064 0.000
M47 Spondylosis
0.933 0.066 0.000
Chapter I Certain infectious and parasitic diseases
0.930 0.070 0.000
S50-S59 Injuries to the elbow and forearm
0.929 0.071 0.000
Chapter VII Diseases of the eye and adnexa
0.921 0.079 0.000
M19 Other arthrosis
0.920 0.080 0.000
G81 Hemiplegia
0.917 0.083 0.000
K50-K52 Noninfective enteritis and colitis
0.915 0.085 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.914 0.086 0.000
H30-H36 Disorders of choroid and retina
0.905 0.095 0.000
M47.8 Other spondylosis
0.904 0.096 0.000
M17 Gonarthrosis [arthrosis of knee]
0.904 0.096 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.902 0.098 0.000
K08.3 Retained dental root
0.902 0.098 0.000
G62 Other polyneuropathies
0.897 0.103 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.889 0.111 0.000
M24 Other specific joint derangements
0.888 0.112 0.000
M80-M85 Disorders of bone density and structure
0.888 0.112 0.000
Chapter IX Diseases of the circulatory system
0.885 0.115 0.000
G81.9 Hemiplegia, unspecified
0.884 0.116 0.000
G20-G26 Extrapyramidal and movement disorders
0.883 0.117 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.882 0.118 0.000
I60-I69 Cerebrovascular diseases
0.879 0.121 0.000
M25.7 Osteophyte
0.870 0.130 0.000
H35 Other retinal disorders
0.868 0.132 0.000
S80 Superficial injury of lower leg
0.867 0.133 0.000
E20-E35 Disorders of other endocrine glands
0.866 0.134 0.000
J93 Pneumothorax
0.866 0.134 0.000
S82 Fracture of lower leg, including ankle
0.864 0.136 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.863 0.137 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.862 0.138 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.861 0.139 0.000
A30-A49 Other bacterial diseases
0.859 0.141 0.000
J91 Pleural effusion in conditions classified elsewhere
0.859 0.141 0.000
E10-E14 Diabetes mellitus
0.858 0.142 0.000
G70-G73 Diseases of myoneural junction and muscle
0.858 0.142 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.851 0.149 0.000
M23.4 Loose body in knee
0.850 0.150 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.849 0.151 0.000
K01 Embedded and impacted teeth
0.848 0.152 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.847 0.153 0.000
J00-J06 Acute upper respiratory infections
0.845 0.155 0.000
M22 Disorders of patella
0.843 0.157 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.840 0.160 0.000
M23.3 Other meniscus derangements
0.840 0.160 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.837 0.163 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.835 0.165 0.000
K09 Cysts of oral region, not elsewhere classified
0.831 0.168 0.000
S52 Fracture of forearm
0.831 0.169 0.000
G90-G99 Other disorders of the nervous system
0.831 0.169 0.000
M17.9 Gonarthrosis, unspecified
0.829 0.171 0.000
H36 Retinal disorders in diseases classified elsewhere
0.829 0.171 0.000
G62.9 Polyneuropathy, unspecified
0.829 0.171 0.000
K30 Dyspepsia
0.827 0.173 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.827 0.173 0.000
O16 Unspecified maternal hypertension
0.827 0.173 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.826 0.174 0.000
I69 Sequelae of cerebrovascular disease
0.825 0.175 0.000
M34 Systemic sclerosis
0.821 0.179 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.820 0.180 0.000
M47.86 Other spondylosis (Lumbar region)
0.820 0.180 0.000
K35-K38 Diseases of appendix
0.820 0.180 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.819 0.181 0.000
A41 Other septicaemia
0.818 0.182 0.000
M46 Other inflammatory spondylopathies
0.817 0.183 0.000
J46 Status asthmaticus
0.816 0.184 0.000
M40-M43 Deforming dorsopathies
0.815 0.185 0.000
K65-K67 Diseases of peritoneum
0.814 0.186 0.000
M91-M94 Chondropathies
0.814 0.186 0.000
G25 Other extrapyramidal and movement disorders
0.814 0.186 0.000
M25.4 Effusion of joint
0.812 0.188 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.811 0.189 0.000
M17.0 Primary gonarthrosis, bilateral
0.811 0.189 0.000
M45 Ankylosing spondylitis
0.810 0.190 0.000
M21 Other acquired deformities of limbs
0.808 0.192 0.000
Q60-Q64 Congenital malformations of the urinary system
0.807 0.193 0.000
M31 Other necrotising vasculopathies
0.806 0.194 0.000
Q50-Q56 Congenital malformations of genital organs
0.806 0.194 0.000
G82 Paraplegia and tetraplegia
0.804 0.196 0.000
M19.9 Arthrosis, unspecified
0.801 0.199 0.000
M25.77 Osteophyte (Ankle and foot)
0.800 0.200 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.797 0.203 0.000
H35.3 Degeneration of macula and posterior pole
0.795 0.205 0.000
M60-M63 Disorders of muscles
0.791 0.209 0.000
K04 Diseases of pulp and periapical tissues
0.790 0.210 0.000
J92 Pleural plaque
0.789 0.211 0.000
M16 Coxarthrosis [arthrosis of hip]
0.786 0.214 0.000
S00-S09 Injuries to the head
0.786 0.214 0.000
O63 Long labour
0.784 0.216 0.000
M30 Polyarteritis nodosa and related conditions
0.781 0.219 0.000
G62.8 Other specified polyneuropathies
0.781 0.219 0.000
K80 Cholelithiasis
0.780 0.220 0.000
I63 Cerebral infarction
0.779 0.221 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.779 0.221 0.000
M05-M14 Inflammatory polyarthropathies
0.778 0.222 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.776 0.224 0.000
H36.0 Diabetic retinopathy
0.775 0.225 0.000
H02 Other disorders of eyelid
0.773 0.227 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.772 0.228 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.771 0.229 0.000
S51 Open wound of forearm
0.770 0.230 0.000
M65-M68 Disorders of synovium and tendon
0.769 0.231 0.000
K50 Crohn's disease [regional enteritis]
0.769 0.231 0.000
A41.8 Other specified septicaemia
0.768 0.232 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.767 0.233 0.000
E16 Other disorders of pancreatic internal secretion
0.767 0.233 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.766 0.233 0.000
S20-S29 Injuries to the thorax
0.766 0.234 0.000
J93.9 Pneumothorax, unspecified
0.764 0.236 0.000
O73 Retained placenta and membranes, without haemorrhage
0.764 0.236 0.000
M84 Disorders of continuity of bone
0.763 0.237 0.000
S89 Other and unspecified injuries of lower leg
0.761 0.239 0.000
M19.0 Primary arthrosis of other joints
0.761 0.239 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.760 0.240 0.000
S10-S19 Injuries to the neck
0.760 0.240 0.000
J02 Acute pharyngitis
0.759 0.241 0.000
K00 Disorders of tooth development and eruption
0.758 0.241 0.000
M48 Other spondylopathies
0.758 0.242 0.000
K51 Ulcerative colitis
0.758 0.242 0.000
S82.0 Fracture of patella
0.758 0.242 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.757 0.243 0.000
M19.1 Posttraumatic arthrosis of other joints
0.757 0.243 0.000
T79-T79 Certain early complications of trauma
0.756 0.244 0.000
H02.8 Other specified disorders of eyelid
0.754 0.246 0.000
E11 Non-insulin-dependent diabetes mellitus
0.753 0.247 0.000
M24.1 Other articular cartilage disorders
0.752 0.248 0.000
O62 Abnormalities of forces of labour
0.752 0.248 0.000
J47 Bronchiectasis
0.752 0.248 0.000
K52 Other non-infective gastro-enteritis and colitis
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.750 0.250 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.748 0.252 0.000
M23.49 Loose body in knee-Unspec lig/men
0.748 0.252 0.000
O72 Postpartum haemorrhage
0.747 0.253 0.000
M00-M03 Infectious arthropathies
0.747 0.253 0.000
Chapter XXII Codes for special purposes
0.747 0.253 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.747 0.253 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.746 0.254 0.000
M85 Other disorders of bone density and structure
0.744 0.256 0.000
M25.3 Other instability of joint
0.744 0.256 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.744 0.256 0.000
K05 Gingivitis and periodontal diseases
0.743 0.256 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.743 0.257 0.000
K02 Dental caries
0.743 0.257 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.742 0.257 0.000
B15-B19 Viral hepatitis
0.741 0.258 0.000
G30-G32 Other degenerative diseases of the nervous system
0.740 0.260 0.000
E23 Hypofunction and other disorders of pituitary gland
0.739 0.260 0.000
M47.1 Other spondylosis with myelopathy
0.739 0.261 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.738 0.262 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.738 0.262 0.000
S70-S79 Injuries to the hip and thigh
0.738 0.262 0.000
S83.2 Tear of meniscus, current
0.737 0.263 0.000
B25-B34 Other viral diseases
0.737 0.263 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.735 0.265 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.735 0.265 0.000
J93.8 Other pneumothorax
0.735 0.265 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.734 0.266 0.000
K11 Diseases of salivary glands
0.732 0.268 0.000
K12 Stomatitis and related lesions
0.731 0.269 0.000
S80.0 Contusion of knee
0.731 0.269 0.000
H35.0 Background retinopathy and retinal vascular changes
0.730 0.270 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.728 0.272 0.000
S82.2 Fracture of shaft of tibia
0.726 0.274 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.724 0.276 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.724 0.276 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.724 0.276 0.000
O70 Perineal laceration during delivery
0.721 0.279 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.721 0.279 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.720 0.280 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.719 0.281 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.719 0.281 0.000
K01.0 Embedded teeth
0.719 0.281 0.000
M16.1 Other primary coxarthrosis
0.719 0.281 0.000
K07 Dentofacial anomalies [including malocclusion]
0.718 0.282 0.000
O85-O92 Complications predominantly related to the puerperium
0.718 0.282 0.000
Q61 Cystic kidney disease
0.718 0.282 0.000
H35.9 Retinal disorder, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M25.71 Osteophyte (Shoulder region)
0.717 0.283 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.716 0.284 0.000
G93 Other disorders of brain
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
Q00-Q07 Congenital malformations of the nervous system
0.715 0.285 0.000
E27 Other disorders of adrenal gland
0.715 0.285 0.000
S82.8 Fractures of other parts of lower leg
0.715 0.285 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.715 0.285 0.000
E16.2 Hypoglycaemia, unspecified
0.714 0.286 0.000
H31 Other disorders of choroid
0.713 0.287 0.000
G80 Infantile cerebral palsy
0.713 0.287 0.000
I63.9 Cerebral infarction, unspecified
0.713 0.287 0.000
S80.9 Superficial injury of lower leg, unspecified
0.712 0.288 0.000
S52.1 Fracture of upper end of radius
0.712 0.288 0.000
J92.0 Pleural plaque with presence of asbestos
0.712 0.288 0.000
M23.9 Internal derangement of knee, unspecified
0.711 0.289 0.000
M23.1 Discoid meniscus (congenital)
0.711 0.289 0.000
M23.0 Cystic meniscus
0.711 0.289 0.000
M22.8 Other disorders of patella
0.711 0.289 0.000
M18 Arthrosis of first carpometacarpal joint
0.711 0.289 0.000
K20 Oesophagitis
0.711 0.289 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.711 0.289 0.000
M13 Other arthritis
0.710 0.290 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.709 0.291 0.000
S09 Other and unspecified injuries of head
0.709 0.291 0.000
M35 Other systemic involvement of connective tissue
0.708 0.292 0.000
E14 Unspecified diabetes mellitus
0.707 0.293 0.000
G70 Myasthenia gravis and other myoneural disorders
0.707 0.293 0.000
J42 Unspecified chronic bronchitis
0.707 0.293 0.000
S50 Superficial injury of forearm
0.707 0.293 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.705 0.295 0.000
M47.89 Other spondylosis (Site unspecified)
0.705 0.295 0.000
M15 Polyarthrosis
0.704 0.295 0.000
M49 Spondylopathies in diseases classified elsewhere
0.703 0.297 0.000
K03 Other diseases of hard tissues of teeth
0.702 0.298 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.702 0.298 0.000
H10-H13 Disorders of conjunctiva
0.702 0.298 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.701 0.298 0.000
K90-K93 Other diseases of the digestive system
0.701 0.299 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.699 0.301 0.000
H35.5 Hereditary retinal dystrophy
0.699 0.301 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.699 0.301 0.000
M43 Other deforming dorsopathies
0.699 0.301 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.698 0.302 0.000
M24.0 Loose body in joint
0.698 0.302 0.000
J02.9 Acute pharyngitis, unspecified
0.698 0.302 0.000
S52.0 Fracture of upper end of ulna
0.698 0.302 0.000
S52.6 Fracture of lower end of both ulna and radius
0.697 0.303 0.000
O80-O84 Delivery
0.697 0.303 0.000
K25 Gastric ulcer
0.696 0.304 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.695 0.305 0.000
S88 Traumatic amputation of lower leg
0.695 0.305 0.000
S87 Crushing injury of lower leg
0.695 0.305 0.000
S86 Injury of muscle and tendon at lower leg level
0.695 0.305 0.000
S85 Injury of blood vessels at lower leg level
0.695 0.305 0.000
S84 Injury of nerves at lower leg level
0.695 0.305 0.000
B95-B98 Bacterial, viral and other infectious agents
0.695 0.305 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
B99-B99 Other infectious diseases
0.694 0.306 0.000
G60 Hereditary and idiopathic neuropathy
0.692 0.308 0.000
Chapter XX External causes of morbidity and mortality
0.692 0.308 0.000
T87 Complications peculiar to reattachment and amputation
0.692 0.308 0.000
E29 Testicular dysfunction
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.308 0.000
K51.2 Ulcerative (chronic) proctitis
0.689 0.311 0.000
M24.2 Disorder of ligament
0.689 0.311 0.000
E11.3 With ophthalmic complications
0.689 0.311 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.688 0.312 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.688 0.312 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.688 0.312 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.687 0.313 0.000
S82.1 Fracture of upper end of tibia
0.686 0.314 0.000
M25.9 Joint disorder, unspecified
0.685 0.315 0.000
M25.2 Flail joint
0.685 0.315 0.000
M25.1 Fistula of joint
0.685 0.315 0.000
M25.0 Haemarthrosis
0.685 0.315 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.684 0.316 0.000
J40 Bronchitis, not specified as acute or chronic
0.683 0.317 0.000
M34.1 CR(E)ST syndrome
0.683 0.317 0.000
S82.00 Fracture of patella (closed)
0.683 0.317 0.000
H34 Retinal vascular occlusions
0.682 0.318 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.682 0.318 0.000
K04.7 Periapical abscess without sinus
0.681 0.319 0.000
K10 Other diseases of jaws
0.681 0.319 0.000
M94 Other disorders of cartilage
0.681 0.319 0.000
J94 Other pleural conditions
0.680 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.680 0.320 0.000
Q80-Q89 Other congenital malformations
0.680 0.320 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.680 0.320 0.000
Q35-Q37 Cleft lip and cleft palate
0.680 0.320 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.680 0.320 0.000
G40-G47 Episodic and paroxysmal disorders
0.679 0.321 0.000
O74 Complications of anaesthesia during labour and delivery
0.679 0.321 0.000
O71 Other obstetric trauma
0.679 0.321 0.000
O66 Other obstructed labour
0.679 0.321 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.679 0.321 0.000
O61 Failed induction of labour
0.679 0.321 0.000
O60 Preterm delivery
0.679 0.321 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.678 0.322 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.678 0.322 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.678 0.322 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.678 0.322 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.678 0.322 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.678 0.322 0.000
K09.0 Developmental odontogenic cysts
0.677 0.323 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.677 0.323 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.677 0.323 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.677 0.323 0.000
M25.46 Effusion of joint (Lower leg)
0.676 0.324 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.676 0.324 0.000
G91 Hydrocephalus
0.675 0.324 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.325 0.000
E22 Hyperfunction of pituitary gland
0.675 0.325 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.675 0.325 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.674 0.326 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.674 0.326 0.000
G64 Other disorders of peripheral nervous system
0.673 0.326 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.673 0.327 0.000
K01.1 Impacted teeth
0.673 0.327 0.000
H05 Disorders of orbit
0.672 0.328 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.328 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.671 0.329 0.000
G82.2 Paraplegia, unspecified
0.671 0.329 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.670 0.330 0.000
K09.2 Other cysts of jaw
0.670 0.330 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.669 0.331 0.000
M23.5 Chronic instability of knee
0.668 0.331 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
G83 Other paralytic syndromes
0.667 0.333 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.667 0.333 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.667 0.333 0.000
B50-B64 Protozoal diseases
0.667 0.333 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.667 0.333 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.667 0.333 0.000
A75-A79 Rickettsioses
0.667 0.333 0.000
A70-A74 Other diseases caused by chlamydiae
0.667 0.333 0.000
A65-A69 Other spirochaetal diseases
0.667 0.333 0.000
A20-A28 Certain zoonotic bacterial diseases
0.667 0.333 0.000
A15-A19 Tuberculosis
0.667 0.333 0.000
S59 Other and unspecified injuries of forearm
0.666 0.334 0.000
S58 Traumatic amputation of forearm
0.666 0.334 0.000
S57 Crushing injury of forearm
0.666 0.334 0.000
S56 Injury of muscle and tendon at forearm level
0.666 0.334 0.000
S55 Injury of blood vessels at forearm level
0.666 0.334 0.000
S54 Injury of nerves at forearm level
0.666 0.334 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.666 0.334 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.666 0.334 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.666 0.334 0.000
E40-E46 Malnutrition
0.665 0.335 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.665 0.335 0.000
G72 Other myopathies
0.664 0.335 0.000
I05-I09 Chronic rheumatic heart diseases
0.663 0.337 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.663 0.337 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.662 0.338 0.000
K86 Other diseases of pancreas
0.661 0.339 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.661 0.339 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
H35.6 Retinal haemorrhage
0.661 0.339 0.000
M13.9 Arthritis, unspecified
0.661 0.339 0.000
E34 Other endocrine disorders
0.661 0.339 0.000
S51.9 Open wound of forearm, part unspecified
0.661 0.339 0.000
M86-M90 Other osteopathies
0.660 0.340 0.000
M25.5 Pain in joint
0.660 0.340 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.659 0.341 0.000
M19.8 Other specified arthrosis
0.659 0.341 0.000
M19.2 Other secondary arthrosis
0.659 0.341 0.000
S80.8 Other superficial injuries of lower leg
0.659 0.341 0.000
S00 Superficial injury of head
0.658 0.342 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.658 0.342 0.000
G81.1 Spastic hemiplegia
0.657 0.343 0.000
G81.0 Flaccid hemiplegia
0.657 0.343 0.000
G71 Primary disorders of muscles
0.656 0.344 0.000
G61 Inflammatory polyneuropathy
0.655 0.345 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.655 0.345 0.000
K36 Other appendicitis
0.654 0.346 0.000
E10 Insulin-dependent diabetes mellitus
0.654 0.346 0.000
J01 Acute sinusitis
0.653 0.347 0.000
S09.9 Unspecified injury of head
0.653 0.347 0.000
O63.0 Prolonged first stage (of labour)
0.653 0.347 0.000
M22.4 Chondromalacia patellae
0.652 0.348 0.000
K66 Other disorders of peritoneum
0.651 0.348 0.000
M80 Osteoporosis with pathological fracture
0.651 0.349 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.649 0.351 0.000
H30 Chorioretinal inflammation
0.649 0.351 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.649 0.351 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.648 0.352 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.648 0.352 0.000
M47.84 Other spondylosis (Thoracic region)
0.648 0.352 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.648 0.352 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.648 0.352 0.000
M17.5 Other secondary gonarthrosis
0.648 0.352 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.648 0.352 0.000
M17.3 Other posttraumatic gonarthrosis
0.648 0.352 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.648 0.352 0.000
J60-J70 Lung diseases due to external agents
0.647 0.353 0.000
O15 Eclampsia
0.647 0.353 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.647 0.353 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.647 0.353 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.647 0.353 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.647 0.353 0.000
A40 Streptococcal septicaemia
0.646 0.353 0.000
M25.8 Other specified joint disorders
0.646 0.354 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.646 0.354 0.000
G24 Dystonia
0.646 0.354 0.000
I61 Intracerebral haemorrhage
0.645 0.355 0.000
Q43 Other congenital malformations of intestine
0.645 0.355 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.645 0.355 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.645 0.355 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.643 0.357 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.643 0.357 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.643 0.357 0.000
G62.2 Polyneuropathy due to other toxic agents
0.643 0.357 0.000
G62.1 Alcoholic polyneuropathy
0.643 0.357 0.000
G62.0 Drug-induced polyneuropathy
0.643 0.357 0.000
S82.5 Fracture of medial malleolus
0.643 0.357 0.000
M85.8 Other specified disorders of bone density and structure
0.642 0.358 0.000
M25.76 Osteophyte (Lower leg)
0.642 0.358 0.000
K50.9 Crohn's disease, unspecified
0.642 0.358 0.000
H01 Other inflammation of eyelid
0.641 0.359 0.000
E28 Ovarian dysfunction
0.641 0.359 0.000
M62 Other disorders of muscle
0.640 0.359 0.000
K25.7 Chronic without haemorrhage or perforation
0.640 0.360 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.639 0.361 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.639 0.361 0.000
G25.0 Essential tremor
0.638 0.362 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.638 0.362 0.000
M25.47 Effusion of joint (Ankle and foot)
0.638 0.362 0.000
K02.8 Other dental caries
0.638 0.362 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.637 0.363 0.000
M24.9 Joint derangement, unspecified
0.637 0.363 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.637 0.363 0.000
M24.7 Protrusio acetabuli
0.637 0.363 0.000
M24.6 Ankylosis of joint
0.637 0.363 0.000
M24.5 Contracture of joint
0.637 0.363 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.637 0.363 0.000
M83 Adult osteomalacia
0.637 0.363 0.000
M82 Osteoporosis in diseases classified elsewhere
0.637 0.363 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.636 0.364 0.000
I60 Subarachnoid haemorrhage
0.635 0.364 0.000
M16.3 Other dysplastic coxarthrosis
0.635 0.365 0.000
I00-I02 Acute rheumatic fever
0.634 0.365 0.000
H35.7 Separation of retinal layers
0.634 0.365 0.000
J20-J22 Other acute lower respiratory infections
0.634 0.366 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.634 0.366 0.000
K65 Peritonitis
0.634 0.366 0.000
G23 Other degenerative diseases of basal ganglia
0.633 0.366 0.000
G21 Secondary Parkinsonism
0.633 0.366 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.633 0.366 0.000
G22 Parkinsonism in diseases classified elsewhere
0.633 0.366 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.633 0.366 0.000
M21.6 Other acquired deformities of ankle and foot
0.633 0.366 0.000
G40 Epilepsy
0.633 0.367 0.000
M21.0 Valgus deformity, not elsewhere classified
0.633 0.367 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.633 0.367 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.632 0.367 0.000
O73.0 Retained placenta, without haemorrhage
0.632 0.368 0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)
0.632 0.368 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.630 0.370 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.630 0.370 0.000
K81 Cholecystitis
0.630 0.370 0.000
H02.1 Ectropion of eyelid
0.630 0.370 0.000
M47.9 Spondylosis, unspecified
0.629 0.371 0.000
S52.10 Fracture of upper end of radius (closed)
0.626 0.373 0.000
T86 Failure and rejection of transplanted organs and tissues
0.626 0.373 0.000
M21.2 Flexion deformity
0.626 0.374 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.626 0.374 0.000
I69.3 Sequelae of cerebral infarction
0.625 0.375 0.000
K38 Other diseases of appendix
0.625 0.375 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.624 0.376 0.000
M25.79 Osteophyte (Site unspecified)
0.624 0.376 0.000
M25.73 Osteophyte (Forearm)
0.624 0.376 0.000
M25.72 Osteophyte (Upper arm)
0.624 0.376 0.000
M25.70 Osteophyte (Multiple sites)
0.624 0.376 0.000
I95 Hypotension
0.624 0.376 0.000
K37 Unspecified appendicitis
0.623 0.377 0.000
H35.2 Other proliferative retinopathy
0.623 0.377 0.000
H35.1 Retinopathy of prematurity
0.623 0.377 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.623 0.377 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.622 0.378 0.000
O63.1 Prolonged second stage (of labour)
0.622 0.378 0.000
S80.7 Multiple superficial injuries of lower leg
0.622 0.378 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.622 0.378 0.000
O20 Haemorrhage in early pregnancy
0.621 0.379 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.621 0.379 0.000
E32 Diseases of thymus
0.621 0.379 0.000
E31 Polyglandular dysfunction
0.621 0.379 0.000
E30 Disorders of puberty, not elsewhere classified
0.621 0.379 0.000
E26 Hyperaldosteronism
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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