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Diagnostic term associations

Hospitalization Episode Statistics (HES)

K21.9
Gastro-oesophageal reflux disease without oesophagitis
Variant effects

Click on a variant to see its association results.

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Genome-wide   Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Results table
Variant Risk
posterior probability
No effect
posterior probability
Protective
posterior probability
 
rs113465333 lBF = 13.2764   Chr8 : 129,756,647
0.871 0.129 0.000
rs62510137 lBF = 19.6427   Chr8 : 64,161,503
0.814 0.186 0.000
rs116424300 lBF = 20.3133   Chr8 : 143,412,988
0.752 0.248 0.000
rs73302752 lBF = 21.6628   Chr8 : 73,279,185
0.712 0.288 0.000
rs28514585 lBF = 20.0653   Chr8 : 129,636,084
0.635 0.365 0.000
rs187899339 lBF = 1.40307   Chr8 : 111,118,450
0.562 0.438 0.000
rs62501302 lBF = 17.5576   Chr8 : 50,545,426
0.558 0.442 0.000
rs78198802 lBF = 14.2898   Chr8 : 22,900,168
0.522 0.478 0.000
rs6995588 lBF = 1.80835   Chr8 : 61,003,897
0.501 0.499 0.000
rs117531883 lBF = 20.9443   Chr8 : 8,309,054
0.476 0.524 0.000
rs187162159 lBF = 0.854917   Chr8 : 25,111,606
0.434 0.565 0.000
rs2106212 lBF = 24.403   Chr8 : 12,569,241
0.397 0.603 0.000
rs34120730 lBF = 12.3059   Chr8 : 75,405,303
0.385 0.615 0.000
rs75631105 lBF = 17.5459   Chr8 : 141,449,601
0.380 0.620 0.000
rs7835454 lBF = 2.03289   Chr8 : 40,034,434
0.316 0.684 0.000
rs77453333 lBF = 13.3291   Chr8 : 8,514,483
0.311 0.689 0.000
rs145959269 lBF = 3.70784   Chr8 : 143,357,023
0.280 0.720 0.000
rs6601606 lBF = 0.475405   Chr8 : 11,638,244
0.273 0.727 0.000
rs16938910 lBF = 0.223122   Chr8 : 75,373,948
0.257 0.743 0.000
rs17372597 lBF = 15.796   Chr8 : 125,595,153
0.248 0.752 0.000
rs479798 lBF = 14.5952   Chr8 : 29,112,073
0.247 0.753 0.000
rs6987665 lBF = 17.3248   Chr8 : 67,655,175
0.243 0.757 0.000
rs118030566 lBF = 27.3147   Chr8 : 144,403,041
0.243 0.757 0.000
rs11992011 lBF = 14.5451   Chr8 : 4,263,916
0.231 0.769 0.000
rs117926607 lBF = 23.2066   Chr8 : 55,468,849
0.225 0.775 0.000
rs74617895 lBF = 13.7107   Chr8 : 3,646,688
0.183 0.817 0.000
rs72659626 lBF = 18.2705   Chr8 : 72,920,433
0.182 0.818 0.000
rs118182320 lBF = 24.3873   Chr8 : 80,951,882
0.180 0.820 0.000
rs185206099 lBF = 1.92922   Chr8 : 6,477,298
0.000 0.828 0.171
rs188420713 lBF = 2.98848   Chr8 : 37,134,189
0.151 0.849 0.000
rs117500008 lBF = 15.3496   Chr8 : 101,671,045
0.145 0.855 0.000
rs3748140 lBF = 15.9864   Chr8 : 8,999,019
0.108 0.892 0.000
rs60336366 lBF = 2.08613   Chr8 : 114,662,251
0.104 0.896 0.000
rs16867579 lBF = 0.536426   Chr8 : 102,375,267
0.099 0.901 0.000
rs17423218 lBF = 17.6829   Chr8 : 67,758,401
0.090 0.910 0.000
rs142507408 lBF = 2.75227   Chr8 : 106,455,558
0.082 0.918 0.000
rs116086868 lBF = 14.4058   Chr8 : 17,448,828
0.075 0.925 0.000
rs141527659 lBF = 22.6507   Chr8 : 130,875,935
0.059 0.941 0.000
rs79560598 lBF = 14.8051   Chr8 : 40,540,751
0.058 0.942 0.000
rs35868637 lBF = 14.7865   Chr8 : 94,743,876
0.055 0.945 0.000
rs79512063 lBF = 24.6388   Chr8 : 89,533,747
0.055 0.945 0.000
rs4397449 lBF = 0.0854969   Chr8 : 90,342,186
0.000 0.947 0.053
rs7011581 lBF = 17.2432   Chr8 : 9,000,465
0.045 0.955 0.000
rs881301 lBF = -0.0216293   Chr8 : 38,332,318
0.044 0.956 0.000
rs7823724 lBF = 6.06735   Chr8 : 141,404,329
0.043 0.957 0.000
rs118124984 lBF = 22.9554   Chr8 : 106,184,779
0.042 0.958 0.000
rs79917365 lBF = 15.1303   Chr8 : 67,459,400
0.040 0.960 0.000
rs4873403 lBF = 0.22757   Chr8 : 50,974,319
0.038 0.961 0.001
rs80301223 lBF = 12.0195   Chr8 : 119,648,160
0.039 0.961 0.000
rs16910714 lBF = 6.38134   Chr8 : 140,496,702
0.037 0.963 0.000
rs34335167 lBF = 6.65121   Chr8 : 143,757,564
0.000 0.964 0.036
rs79369118 lBF = 12.8136   Chr8 : 89,693,007
0.032 0.968 0.000
rs113040697 lBF = 28.1855   Chr8 : 118,185,308
0.032 0.968 0.000
rs75779669 lBF = 19.3932   Chr8 : 20,955,032
0.031 0.969 0.000
rs28359524 lBF = 12.4863   Chr8 : 18,076,854
0.031 0.969 0.000
rs117194321 lBF = 19.8711   Chr8 : 22,491,317
0.028 0.972 0.000
rs74664674 lBF = 18.0774   Chr8 : 105,468,730
0.025 0.975 0.000
rs56229264 lBF = 17.6142   Chr8 : 27,321,189
0.023 0.977 0.000
rs186868868 lBF = 23.5439   Chr8 : 19,863,803
0.023 0.977 0.000
rs4645543 lBF = 3.51242   Chr8 : 140,496,242
0.020 0.980 0.000
rs78714084 lBF = 18.8347   Chr8 : 89,031,066
0.020 0.980 0.000
rs2294008 lBF = 21.3866   Chr8 : 143,761,931
0.000 0.981 0.019
rs11784918 lBF = 15.2667   Chr8 : 24,457,456
0.017 0.983 0.000
rs72630661 lBF = 19.6221   Chr8 : 38,329,982
0.017 0.983 0.000
rs16905439 lBF = 6.71325   Chr8 : 136,989,204
0.015 0.985 0.000
rs75609241 lBF = 0.288686   Chr8 : 29,082,285
0.015 0.985 0.000
rs1045531 lBF = 21.1209   Chr8 : 143,763,547
0.000 0.986 0.014
rs16876083 lBF = 1.85429   Chr8 : 29,716,261
0.013 0.986 0.001
rs830478 lBF = 9.24249   Chr8 : 73,372,875
0.014 0.986 0.000
rs116951791 lBF = 8.04751   Chr8 : 93,219,721
0.014 0.986 0.000
rs2976387 lBF = 24.3072   Chr8 : 143,759,364
0.000 0.987 0.013
rs75729198 lBF = 19.6792   Chr8 : 15,885,087
0.013 0.987 0.000
rs117405208 lBF = 11.2682   Chr8 : 134,967,408
0.013 0.987 0.000
rs140273521 lBF = 15.1391   Chr8 : 136,277,752
0.013 0.987 0.000
rs1441759 lBF = 22.8185   Chr8 : 19,865,563
0.013 0.987 0.000
rs188140481 lBF = 18.2034   Chr8 : 128,191,672
0.013 0.987 0.000
rs16887217 lBF = 0.00876989   Chr8 : 38,004,425
0.012 0.988 0.000
rs17727296 lBF = 13.2947   Chr8 : 72,558,829
0.011 0.989 0.000
rs76308827 lBF = 22.5688   Chr8 : 80,264,727
0.011 0.989 0.000
rs77959025 lBF = 16.9241   Chr8 : 128,761,169
0.010 0.989 0.000
rs12541902 lBF = 1.19166   Chr8 : 60,623,348
0.009 0.991 0.000
rs4424296 lBF = 0.0647184   Chr8 : 120,013,276
0.009 0.991 0.000
rs117956319 lBF = 13.4307   Chr8 : 32,191,896
0.009 0.991 0.000
rs117366179 lBF = 16.6572   Chr8 : 14,733,658
0.008 0.992 0.000
rs138042437 lBF = 17.9564   Chr8 : 128,208,369
0.007 0.993 0.000
rs7459527 lBF = 0.0670646   Chr8 : 118,909,260
0.007 0.993 0.000
rs2720508 lBF = 0.0204018   Chr8 : 17,329,827
0.000 0.993 0.007
rs1801177 lBF = 13.37   Chr8 : 19,805,708
0.007 0.993 0.000
rs73204665 lBF = 14.5549   Chr8 : 9,621,236
0.006 0.993 0.000
rs79323383 lBF = 0.0813721   Chr8 : 121,851,425
0.006 0.994 0.000
rs76188673 lBF = 12.8925   Chr8 : 2,443,492
0.006 0.994 0.000
rs149232124 lBF = -0.00106835   Chr8 : 107,335,395
0.000 0.994 0.006
rs4737547 lBF = 0.194995   Chr8 : 60,545,664
0.000 0.994 0.006
rs117984108 lBF = 20.8253   Chr8 : 22,983,095
0.006 0.994 0.000
rs191939331 lBF = 1.86657   Chr8 : 84,717,650
0.005 0.995 0.000
rs59294057 lBF = 0.0130314   Chr8 : 21,506,668
0.005 0.995 0.000
rs150335055 lBF = 0.00517963   Chr8 : 9,244,264
0.005 0.995 0.000
rs77303430 lBF = 9.49687   Chr8 : 99,875,745
0.005 0.995 0.000
rs10504249 lBF = 0.015296   Chr8 : 58,789,081
0.000 0.995 0.005
rs2103225 lBF = 7.68348   Chr8 : 77,219,328
0.005 0.995 0.000
rs117809070 lBF = 22.8902   Chr8 : 67,282,208
0.004 0.996 0.000
rs150488832 lBF = 17.2688   Chr8 : 36,201,248
0.004 0.996 0.000
rs117873316 lBF = 14.6834   Chr8 : 135,652,254
0.003 0.997 0.000
rs35925379 lBF = 0.00225855   Chr8 : 144,802,456
0.003 0.997 0.000
rs12676637 lBF = 6.77263   Chr8 : 15,770,661
0.003 0.997 0.000
rs2255327 lBF = 0.00267889   Chr8 : 11,409,992
0.002 0.997 0.000
rs978152 lBF = -0.0405618   Chr8 : 133,369,094
0.003 0.997 0.000
rs13264644 lBF = 12.9386   Chr8 : 143,753,546
0.003 0.997 0.000
rs183826639 lBF = 0.489777   Chr8 : 76,817,264
0.002 0.997 0.000
rs4736655 lBF = 0.00443393   Chr8 : 134,350,106
0.002 0.997 0.000
rs117262625 lBF = 15.8812   Chr8 : 21,089,037
0.003 0.997 0.000
rs77942316 lBF = 2.53949   Chr8 : 92,359,337
0.000 0.997 0.003
rs4872511 lBF = 0.0384953   Chr8 : 22,400,989
0.002 0.997 0.000
rs117857023 lBF = 14.423   Chr8 : 10,675,065
0.002 0.998 0.000
rs74342708 lBF = 21.3644   Chr8 : 22,572,749
0.002 0.998 0.000
rs141088253 lBF = 0.00162185   Chr8 : 5,284,296
0.002 0.998 0.000
rs17128007 lBF = -0.00360267   Chr8 : 19,083,152
0.000 0.998 0.002
rs4437673 lBF = -0.00180243   Chr8 : 6,758,698
0.002 0.998 0.000
rs6586977 lBF = 0.0140925   Chr8 : 21,156,593
0.002 0.998 0.000
rs16906293 lBF = 0.00055016   Chr8 : 137,768,892
0.001 0.998 0.000
rs4342585 lBF = 0.0008069   Chr8 : 74,467,504
0.000 0.998 0.002
rs77822622 lBF = 16.7219   Chr8 : 57,929,662
0.002 0.998 0.000
rs61496269 lBF = 0.00050382   Chr8 : 139,608,718
0.001 0.998 0.000
rs1460237 lBF = 0.0194697   Chr8 : 105,841,855
0.002 0.998 0.000
rs11995824 lBF = 0.00378026   Chr8 : 120,012,700
0.001 0.999 0.000
rs6982751 lBF = 0.174968   Chr8 : 10,813,474
0.000 0.999 0.001
rs74896277 lBF = 17.349   Chr8 : 131,131,148
0.001 0.999 0.000
rs77609452 lBF = 0.00177264   Chr8 : 26,312,097
0.001 0.999 0.000
rs2351326 lBF = 12.3551   Chr8 : 111,847,246
0.001 0.999 0.000
rs150281976 lBF = 0.00104432   Chr8 : 25,131,459
0.001 0.999 0.000
rs2280890 lBF = 0.00592004   Chr8 : 22,404,840
0.001 0.999 0.000
rs118061259 lBF = -0.00006118   Chr8 : 107,828,078
0.001 0.999 0.000
rs2585174 lBF = 11.5953   Chr8 : 143,782,044
0.001 0.999 0.000
rs151198427 lBF = -0.00005693   Chr8 : 68,351,787
0.001 0.999 0.000
rs28493987 lBF = 0.00029576   Chr8 : 75,341,097
0.000 0.999 0.001
rs2954022 lBF = 0.00028347   Chr8 : 126,482,621
0.000 0.999 0.001
rs147913210 lBF = 0.00024086   Chr8 : 25,130,233
0.001 0.999 0.000
rs16904316 lBF = 0.00025085   Chr8 : 131,617,850
0.001 0.999 0.000
rs7015622 lBF = 0.00012047   Chr8 : 83,903,814
0.001 0.999 0.000
rs192316701 lBF = 0.00007261   Chr8 : 1,456,068
0.001 0.999 0.000
rs113367091 lBF = 0.00003576   Chr8 : 12,892,858
0.001 0.999 0.000
rs12542677 lBF = 0.00006733   Chr8 : 56,168,059
0.000 0.999 0.001
rs186046079 lBF = 0.00004726   Chr8 : 6,468,714
0.001 0.999 0.000
rs190951784 lBF = 0.00003382   Chr8 : 25,131,523
0.001 0.999 0.000
rs73318770 lBF = 0.00000446   Chr8 : 74,362,915
0.001 0.999 0.000
rs116041037 lBF = 0   Chr8 : 128,131,809
0.001 0.999 0.001
rs183191361 lBF = 0   Chr8 : 76,083,247
0.001 0.999 0.001
rs79781504 lBF = 0   Chr8 : 84,750,057
0.001 0.999 0.001
rs182115318 lBF = 0   Chr8 : 25,128,723
0.001 0.999 0.001
rs16902104 lBF = 0   Chr8 : 128,340,908
0.001 0.999 0.001
rs182302106 lBF = 0   Chr8 : 1,455,175
0.001 0.999 0.001
rs187636186 lBF = 0   Chr8 : 73,002,468
0.001 0.999 0.001
rs141395649 lBF = 0   Chr8 : 6,498,690
0.001 0.999 0.001
rs114252942 lBF = 0   Chr8 : 6,202,964
0.001 0.999 0.001
rs116129203 lBF = 0   Chr8 : 6,779,323
0.001 0.999 0.001
rs114258913 lBF = 0   Chr8 : 93,525,403
0.001 0.999 0.001
rs150435906 lBF = 0   Chr8 : 66,864,338
0.001 0.999 0.001
rs144424757 lBF = 0   Chr8 : 12,929,793
0.001 0.999 0.001
rs11989122 lBF = 0   Chr8 : 118,827,839
0.001 0.999 0.001
rs11986011 lBF = 0   Chr8 : 127,332,657
0.001 0.999 0.001
rs191631123 lBF = 0   Chr8 : 32,443,704
0.001 0.999 0.001
rs4128527 lBF = 0   Chr8 : 72,682,693
0.001 0.999 0.001
rs1845529 lBF = 0   Chr8 : 116,163,863
0.001 0.999 0.001
rs113414285 lBF = 0   Chr8 : 24,395,263
0.001 0.999 0.001
rs182838111 lBF = 0   Chr8 : 67,889,470
0.001 0.999 0.001
rs182387400 lBF = 0   Chr8 : 25,129,708
0.001 0.999 0.001
rs192074192 lBF = 0   Chr8 : 73,025,833
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs188809019 lBF = 0   Chr8 : 129,286,235
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs141721054 lBF = 0   Chr8 : 131,201,613
0.001 0.999 0.001
rs188858915 lBF = 0   Chr8 : 6,494,833
0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
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0.001 0.999 0.001
rs113660214 lBF = 0   Chr8 : 977,436
0.001 0.999 0.001
rs147852159 lBF = 0   Chr8 : 146,171,164
0.001 0.999 0.001
rs201734206 lBF = 0   Chr8 : 73,984,100
0.001 0.999 0.001
rs192994403 lBF = 0   Chr8 : 76,211,333
0.001 0.999 0.001
rs189590409 lBF = 0   Chr8 : 114,727,602
0.001 0.999 0.001
rs4875284 lBF = -0.00003065   Chr8 : 3,978,130
0.001 0.999 0.000
rs183529902 lBF = -0.00000969   Chr8 : 35,880,032
0.001 0.999 0.000
rs7004587 lBF = -0.00002087   Chr8 : 108,040,352
0.000 0.999 0.001
rs138094162 lBF = -0.00002448   Chr8 : 6,489,568
0.001 0.999 0.000
rs10107366 lBF = -0.00003159   Chr8 : 99,113,687
0.001 0.999 0.000
rs2737229 lBF = 0.177448   Chr8 : 116,648,565
0.000 0.999 0.001
rs538641 lBF = 0.012945   Chr8 : 103,003,703
0.000 0.999 0.001
rs2585135 lBF = 8.94511   Chr8 : 143,814,193
0.001 0.999 0.000
rs75835816 lBF = 7.35402   Chr8 : 19,885,513
0.001 0.999 0.000
rs6993449 lBF = -0.0949468   Chr8 : 108,281,427
0.001 0.999 0.000
rs77119043 lBF = 15.2787   Chr8 : 48,313,295
0.001 0.999 0.000
rs74357743 lBF = 13.6586   Chr8 : 74,712,506
0.001 0.999 0.000
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0.001 0.999 0.000
rs10108954 lBF = 1.89999   Chr8 : 8,722,378
0.001 0.999 0.000
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0.000 0.999 0.001
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.000
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
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0.000 0.999 0.001
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0.001 0.999 0.000
rs147368169 lBF = 2.47816   Chr8 : 143,470,843
0.001 0.999 0.000
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0.000 0.999 0.000
rs6993813 lBF = 0.151365   Chr8 : 120,052,238
0.001 0.999 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
rs117336177 lBF = 15.6541   Chr8 : 66,701,846
0.000 1.000 0.000
rs71522756 lBF = 14.0585   Chr8 : 106,746,337
0.000 1.000 0.000
rs6469804 lBF = 0.816679   Chr8 : 120,044,829
0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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0.000 1.000 0.000
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rs10093547 lBF = 12.0083   Chr8 : 77,474,545
0.000 1.000 0.000
rs11985641 lBF = 11.8964   Chr8 : 2,281,867
0.000 1.000 0.000
rs73542936 lBF = 11.6477   Chr8 : 1,839,557
0.000 1.000 0.000
rs10216564 lBF = 11.5477   Chr8 : 77,475,130
0.000 1.000 0.000
rs28727938 lBF = 11.5371   Chr8 : 77,478,539
0.000 1.000 0.000
rs76594396 lBF = 11.0301   Chr8 : 5,443,735
0.000 1.000 0.000
rs77237430 lBF = 10.8581   Chr8 : 117,500,622
0.000 1.000 0.000
rs13248610 lBF = 10.5334   Chr8 : 77,460,493
0.000 1.000 0.000
rs74912350 lBF = 10.4081   Chr8 : 96,035,756
0.000 1.000 0.000
rs117172322 lBF = 9.83651   Chr8 : 39,522,372
0.000 1.000 0.000
Affx-31406520 lBF = 9.74408   Chr8 : 117,783,975
0.000 1.000 0.000
rs7828067 lBF = 8.85726   Chr8 : 117,796,195
0.000 1.000 0.000
rs76809594 lBF = 8.33722   Chr8 : 25,639,271
0.000 1.000 0.000
rs7829065 lBF = 8.29515   Chr8 : 9,396,649
0.000 1.000 0.000
rs2304877 lBF = 8.23168   Chr8 : 41,566,438
0.000 1.000 0.000
rs17066040 lBF = 8.08905   Chr8 : 3,270,667
0.000 1.000 0.000
rs78216664 lBF = 7.58546   Chr8 : 32,068,317
0.000 1.000 0.000
rs2927021 lBF = 7.556   Chr8 : 120,363,974
0.000 1.000 0.000
rs71519872 lBF = 7.54418   Chr8 : 2,302,138
0.000 1.000 0.000
rs73198922 lBF = 7.10026   Chr8 : 10,958,663
0.000 1.000 0.000
rs11785559 lBF = 6.9921   Chr8 : 129,300,304
0.000 1.000 0.000
rs13248930 lBF = 6.94247   Chr8 : 125,664,204
0.000 1.000 0.000
rs12545092 lBF = 6.89488   Chr8 : 19,520,367
0.000 1.000 0.000
rs1805860 lBF = 6.63278   Chr8 : 91,022,867
0.000 1.000 0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

 
Variant clusters with highest protective effect

(posterior probability > 0.05)

Variant clusters with highest risk effect

(posterior probability > 0.05)