TreeWAS – Aortic valve disease

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs117564322 lBF = `2.69692` Chr`7` : `150,684,021`	0.485	0.515	0.000
rs3918226 lBF = `12.2695` Chr`7` : `150,690,176`	0.377	0.622	0.000
rs11556924 lBF = `4.7389` Chr`7` : `129,663,496`	0.000	0.677	0.323
rs2107595 lBF = `3.80288` Chr`7` : `19,049,388`	0.279	0.720	0.000
rs57301765 lBF = `2.99028` Chr`7` : `19,052,733`	0.249	0.751	0.001
rs73066442 lBF = `7.61964` Chr`7` : `21,592,973`	0.086	0.914	0.000
rs17398575 lBF = `0.0504539` Chr`7` : `106,409,452`	0.030	0.970	0.000
rs113118439 lBF = `0.191513` Chr`7` : `5,487,229`	0.028	0.972	0.000
rs55649657 lBF = `9.56022` Chr`7` : `21,607,283`	0.023	0.977	0.000
rs77224425 lBF = `0.117562` Chr`7` : `36,087,216`	0.022	0.978	0.000
rs6976769 lBF = `0.103028` Chr`7` : `83,297,262`	0.015	0.985	0.000
rs798502 lBF = `1.54652` Chr`7` : `2,789,880`	0.000	0.986	0.014
rs56130071 lBF = `8.99314` Chr`7` : `21,598,753`	0.013	0.987	0.000
rs13245899 lBF = `0.0577771` Chr`7` : `100,497,131`	0.011	0.989	0.000
rs798497 lBF = `1.60686` Chr`7` : `2,795,957`	0.000	0.990	0.010
rs798544 lBF = `0.76856` Chr`7` : `2,763,102`	0.000	0.991	0.009
rs12666989 lBF = `0.0549091` Chr`7` : `100,486,754`	0.009	0.991	0.000
rs12670798 lBF = `7.77205` Chr`7` : `21,607,352`	0.008	0.992	0.000
rs314370 lBF = `0.106906` Chr`7` : `100,453,208`	0.008	0.992	0.000
rs797820 lBF = `-0.0891298` Chr`7` : `83,609,039`	0.000	0.992	0.008
rs7777484 lBF = `0.00808249` Chr`7` : `2,814,271`	0.000	0.992	0.008
rs11773845 lBF = `7.55688` Chr`7` : `116,191,301`	0.007	0.993	0.000
rs1182188 lBF = `0.972482` Chr`7` : `2,869,985`	0.000	0.993	0.007
rs798554 lBF = `0.876726` Chr`7` : `2,759,795`	0.000	0.993	0.007
rs3807989 lBF = `7.39522` Chr`7` : `116,186,241`	0.007	0.993	0.000
rs191603973 lBF = `0.0684295` Chr`7` : `155,101,686`	0.006	0.994	0.000
rs9920 lBF = `2.25442` Chr`7` : `116,200,092`	0.000	0.994	0.006
rs2074633 lBF = `0.0724459` Chr`7` : `19,035,920`	0.005	0.994	0.000
rs798489 lBF = `0.758014` Chr`7` : `2,801,803`	0.000	0.995	0.005
rs4646450 lBF = `0.0090158` Chr`7` : `99,266,318`	0.000	0.995	0.005
rs17477177 lBF = `-0.0569173` Chr`7` : `106,411,858`	0.005	0.995	0.000
rs146131423 lBF = `0.012458` Chr`7` : `75,896,741`	0.005	0.995	0.000
rs75672964 lBF = `0.115217` Chr`7` : `131,321,010`	0.004	0.995	0.000
rs3757584 lBF = `0.887582` Chr`7` : `73,440,695`	0.004	0.995	0.000
rs1800795 lBF = `0.744038` Chr`7` : `22,766,645`	0.000	0.996	0.004
rs11978472 lBF = `-0.103335` Chr`7` : `81,839,553`	0.004	0.996	0.000
rs10270308 lBF = `0.0722869` Chr`7` : `105,671,267`	0.004	0.996	0.000
rs4410790 lBF = `0.261217` Chr`7` : `17,284,577`	0.000	0.996	0.003
rs6968554 lBF = `0.321945` Chr`7` : `17,287,106`	0.000	0.997	0.003
rs2286195 lBF = `0.0470075` Chr`7` : `139,728,584`	0.001	0.997	0.002
rs192739715 lBF = `0.129257` Chr`7` : `52,165,757`	0.003	0.997	0.000
rs6465657 lBF = `0.251497` Chr`7` : `97,816,327`	0.003	0.997	0.000
rs10486003 lBF = `-0.0346589` Chr`7` : `97,229,778`	0.003	0.997	0.000
rs875971 lBF = `-0.064761` Chr`7` : `65,617,595`	0.003	0.997	0.000
rs1142 lBF = `-0.00494433` Chr`7` : `104,756,326`	0.003	0.997	0.000
rs1668357 lBF = `-0.0835611` Chr`7` : `38,004,406`	0.000	0.997	0.003
rs6968865 lBF = `0.305479` Chr`7` : `17,287,269`	0.000	0.997	0.003
rs6465657 lBF = `0.254668` Chr`7` : `97,816,327`	0.000	0.997	0.003
rs929351 lBF = `-0.131206` Chr`7` : `81,857,893`	0.000	0.997	0.003
rs73313346 lBF = `-0.0168476` Chr`7` : `18,723,232`	0.002	0.998	0.000
rs72602052 lBF = `0.0470946` Chr`7` : `28,500,531`	0.002	0.998	0.000
rs14978 lBF = `-0.0576826` Chr`7` : `12,273,152`	0.002	0.998	0.000
rs6462018 lBF = `-0.102586` Chr`7` : `27,519,118`	0.002	0.998	0.000
rs12670403 lBF = `-0.108911` Chr`7` : `17,309,279`	0.000	0.998	0.002
rs75511781 lBF = `0.249713` Chr`7` : `131,323,710`	0.002	0.998	0.000
rs6949729 lBF = `0.796616` Chr`7` : `141,362,431`	0.002	0.998	0.000
rs3736638 lBF = `0.040438` Chr`7` : `94,047,266`	0.002	0.998	0.000
rs7800668 lBF = `-0.0420779` Chr`7` : `117,459,043`	0.000	0.998	0.002
rs113308315 lBF = `0.0401956` Chr`7` : `49,916,006`	0.002	0.998	0.000
rs79091781 lBF = `0.0106729` Chr`7` : `94,430,452`	0.002	0.998	0.000
rs1499614 lBF = `-0.0637016` Chr`7` : `65,730,798`	0.002	0.998	0.000
rs10251504 lBF = `0.060002` Chr`7` : `77,689,888`	0.000	0.998	0.002
rs11977526 lBF = `-0.155798` Chr`7` : `46,008,110`	0.002	0.998	0.000
rs1534696 lBF = `-0.191619` Chr`7` : `26,397,239`	0.000	0.998	0.002
rs2299148 lBF = `-0.07979` Chr`7` : `42,023,400`	0.002	0.998	0.000
rs7802124 lBF = `3.01338` Chr`7` : `116,205,914`	0.000	0.998	0.002
rs9638182 lBF = `6.81008` Chr`7` : `72,999,105`	0.000	0.998	0.002
rs2730245 lBF = `-0.178241` Chr`7` : `158,724,789`	0.002	0.998	0.000
rs2243480 lBF = `-0.0657767` Chr`7` : `65,599,196`	0.000	0.998	0.002
rs245914 lBF = `-0.193882` Chr`7` : `29,218,159`	0.002	0.998	0.000
rs4718428 lBF = `-0.111944` Chr`7` : `66,421,446`	0.000	0.998	0.002
rs13247874 lBF = `6.8808` Chr`7` : `73,010,442`	0.000	0.998	0.002
rs73099187 lBF = `0.323718` Chr`7` : `35,291,491`	0.000	0.998	0.001
rs2097677 lBF = `0.220577` Chr`7` : `22,732,839`	0.000	0.998	0.001
rs308097 lBF = `0.0257695` Chr`7` : `5,880,377`	0.001	0.998	0.000
rs4729260 lBF = `0.600487` Chr`7` : `96,117,918`	0.000	0.998	0.001
rs7781370 lBF = `0.527702` Chr`7` : `96,133,531`	0.000	0.998	0.001
rs4727338 lBF = `0.383343` Chr`7` : `96,120,675`	0.000	0.998	0.001
rs13236243 lBF = `0.142947` Chr`7` : `17,318,312`	0.000	0.998	0.001
rs17172199 lBF = `-0.0895872` Chr`7` : `43,377,276`	0.001	0.999	0.000
rs76720445 lBF = `0.389604` Chr`7` : `1,792,396`	0.001	0.999	0.000
rs13307587 lBF = `-0.162184` Chr`7` : `13,543,729`	0.001	0.999	0.000
rs4721377 lBF = `-0.191544` Chr`7` : `14,855,062`	0.000	0.999	0.001
rs17168526 lBF = `0.00588784` Chr`7` : `7,571,420`	0.001	0.999	0.000
rs10255329 lBF = `0.0105716` Chr`7` : `13,440,222`	0.001	0.999	0.000
rs17140875 lBF = `-0.049162` Chr`7` : `19,248,278`	0.001	0.999	0.000
rs10808265 lBF = `-0.14568` Chr`7` : `132,189,689`	0.000	0.999	0.001
rs1635852 lBF = `1.34958` Chr`7` : `28,189,411`	0.000	0.999	0.001
rs5009270 lBF = `0.152921` Chr`7` : `112,159,178`	0.000	0.999	0.001
rs1010366 lBF = `-0.134344` Chr`7` : `7,229,826`	0.001	0.999	0.000
rs4725479 lBF = `-0.164217` Chr`7` : `152,745,810`	0.001	0.999	0.000
rs1357978 lBF = `-0.166378` Chr`7` : `13,560,221`	0.001	0.999	0.000
rs11765845 lBF = `-0.217868` Chr`7` : `28,391,142`	0.000	0.999	0.001
rs3812316 lBF = `10.0283` Chr`7` : `73,020,337`	0.000	0.999	0.001
rs849134 lBF = `1.6481` Chr`7` : `28,196,222`	0.001	0.999	0.000
rs13227425 lBF = `-0.165341` Chr`7` : `13,554,008`	0.001	0.999	0.000
rs10239506 lBF = `-0.176572` Chr`7` : `32,216,893`	0.000	0.999	0.001
rs75655068 lBF = `0.0676733` Chr`7` : `92,658,364`	0.001	0.999	0.000
rs6954895 lBF = `-0.0365626` Chr`7` : `35,586,206`	0.000	0.999	0.001
rs1179624 lBF = `-0.217269` Chr`7` : `75,255,215`	0.000	0.999	0.001
rs38989 lBF = `-0.229234` Chr`7` : `153,578,416`	0.001	0.999	0.000
rs10237735 lBF = `-0.00103009` Chr`7` : `32,376,748`	0.001	0.999	0.000
rs186166891 lBF = `6.92511` Chr`7` : `40,406,876`	0.001	0.999	0.000
rs2533291 lBF = `0.0266391` Chr`7` : `157,505,654`	0.001	0.999	0.000
rs17150687 lBF = `0.00292372` Chr`7` : `78,043,291`	0.001	0.999	0.000
rs7809615 lBF = `-0.054376` Chr`7` : `99,184,778`	0.000	0.999	0.001
rs11974702 lBF = `-0.0399583` Chr`7` : `99,163,951`	0.000	0.999	0.001
rs11772815 lBF = `-0.178293` Chr`7` : `28,391,047`	0.000	0.999	0.001
rs71564781 lBF = `-0.029514` Chr`7` : `106,041,964`	0.001	0.999	0.000
rs10229603 lBF = `-0.17213` Chr`7` : `112,628,373`	0.001	0.999	0.000
rs6466479 lBF = `0.153155` Chr`7` : `113,741,105`	0.001	0.999	0.000
rs10262624 lBF = `-0.178947` Chr`7` : `23,915,676`	0.000	0.999	0.001
rs7807441 lBF = `-0.209233` Chr`7` : `67,188,788`	0.001	0.999	0.000
rs10226930 lBF = `0.00011944` Chr`7` : `155,837,295`	0.001	0.999	0.000
rs3779195 lBF = `-0.0556003` Chr`7` : `97,993,362`	0.001	0.999	0.000
rs1488515 lBF = `-0.0842441` Chr`7` : `95,631,196`	0.001	0.999	0.000
rs10278040 lBF = `-0.0399143` Chr`7` : `99,141,373`	0.000	0.999	0.001
rs7802263 lBF = `-0.114815` Chr`7` : `124,384,327`	0.000	0.999	0.001
rs7812088 lBF = `-0.0591249` Chr`7` : `150,919,829`	0.001	0.999	0.000
rs2429582 lBF = `-0.175345` Chr`7` : `122,202,593`	0.000	0.999	0.001
rs183498415 lBF = `0.00472176` Chr`7` : `35,153,401`	0.001	0.999	0.000
rs6951258 lBF = `0.00136696` Chr`7` : `37,757,556`	0.001	0.999	0.000
rs1122979 lBF = `-0.0507835` Chr`7` : `150,915,071`	0.001	0.999	0.000
rs849142 lBF = `1.93781` Chr`7` : `28,185,891`	0.000	0.999	0.001
rs849134 lBF = `1.86294` Chr`7` : `28,196,222`	0.000	0.999	0.001
rs73692310 lBF = `0.0009303` Chr`7` : `46,006,655`	0.001	0.999	0.000
rs13228694 lBF = `-0.0140537` Chr`7` : `99,940,307`	0.000	0.999	0.001
rs372229746 lBF = `-0.0571606` Chr`7` : `102,158,815`	0.001	0.999	0.000
rs1859596 lBF = `-0.0646987` Chr`7` : `79,109,642`	0.001	0.999	0.000
rs13226650 lBF = `6.67591` Chr`7` : `73,017,005`	0.000	0.999	0.001
rs864745 lBF = `2.2156` Chr`7` : `28,180,556`	0.000	0.999	0.001
rs10275663 lBF = `0.00439393` Chr`7` : `50,797,685`	0.001	0.999	0.000
rs17158483 lBF = `-0.0870729` Chr`7` : `29,962,524`	0.001	0.999	0.000
rs11766496 lBF = `4.89221` Chr`7` : `71,388,850`	0.001	0.999	0.000
rs1000597 lBF = `0.719228` Chr`7` : `30,937,178`	0.001	0.999	0.000
rs7795747 lBF = `0.00154375` Chr`7` : `150,361,718`	0.001	0.999	0.000
rs10268774 lBF = `-0.00030205` Chr`7` : `82,082,438`	0.001	0.999	0.000
rs190817748 lBF = `0.00097909` Chr`7` : `52,139,578`	0.001	0.999	0.000
rs111588657 lBF = `0.00095276` Chr`7` : `52,133,803`	0.001	0.999	0.000
rs6459680 lBF = `0.00061255` Chr`7` : `156,258,568`	0.001	0.999	0.000
rs1358075 lBF = `0.00027899` Chr`7` : `146,135,938`	0.001	0.999	0.000
rs12533251 lBF = `-0.0631193` Chr`7` : `99,115,677`	0.000	0.999	0.001
rs4730775 lBF = `-0.077965` Chr`7` : `116,917,118`	0.000	0.999	0.001
rs149619169 lBF = `0.00139553` Chr`7` : `151,739,052`	0.001	0.999	0.000
rs77443149 lBF = `0.00097179` Chr`7` : `97,924,554`	0.001	0.999	0.000
rs73366442 lBF = `-0.0314434` Chr`7` : `73,989,491`	0.001	0.999	0.000
rs343064 lBF = `0.00847925` Chr`7` : `35,554,788`	0.001	0.999	0.000
rs60839105 lBF = `0.00094745` Chr`7` : `80,492,357`	0.001	0.999	0.000
rs62468398 lBF = `-0.0562702` Chr`7` : `131,893,485`	0.001	0.999	0.000
rs17151904 lBF = `-0.165745` Chr`7` : `25,608,409`	0.000	0.999	0.001
rs79209880 lBF = `0.0539908` Chr`7` : `45,710,099`	0.001	0.999	0.000
rs73737676 lBF = `0.00442559` Chr`7` : `155,810,501`	0.001	0.999	0.000
rs140817150 lBF = `0.00000428` Chr`7` : `13,396,630`	0.001	0.999	0.000
rs10266254 lBF = `0` Chr`7` : `89,763,864`	0.001	0.999	0.001
rs191698899 lBF = `0` Chr`7` : `94,015,730`	0.001	0.999	0.001
rs149774937 lBF = `0` Chr`7` : `151,737,020`	0.001	0.999	0.001
rs9771228 lBF = `0` Chr`7` : `32,322,496`	0.001	0.999	0.001
rs139110493 lBF = `0` Chr`7` : `75,209,951`	0.001	0.999	0.001
rs12666870 lBF = `0` Chr`7` : `78,158,472`	0.001	0.999	0.001
rs74464075 lBF = `0` Chr`7` : `86,874,077`	0.001	0.999	0.001
rs192462116 lBF = `0` Chr`7` : `94,767,406`	0.001	0.999	0.001
rs114302618 lBF = `0` Chr`7` : `93,967,060`	0.001	0.999	0.001
rs183464040 lBF = `0` Chr`7` : `125,610,713`	0.001	0.999	0.001
rs150256815 lBF = `0` Chr`7` : `151,743,793`	0.001	0.999	0.001
rs76742446 lBF = `0` Chr`7` : `155,072,619`	0.001	0.999	0.001
rs141892389 lBF = `0` Chr`7` : `151,716,711`	0.001	0.999	0.001
rs4732446 lBF = `0` Chr`7` : `82,002,217`	0.001	0.999	0.001
rs806215 lBF = `0` Chr`7` : `127,237,312`	0.001	0.999	0.001
rs8192851 lBF = `0` Chr`7` : `139,687,304`	0.001	0.999	0.001
rs74629737 lBF = `0` Chr`7` : `34,093,454`	0.001	0.999	0.001
rs188593748 lBF = `0` Chr`7` : `108,157,222`	0.001	0.999	0.001
rs11982969 lBF = `0` Chr`7` : `142,141,746`	0.001	0.999	0.001
rs886448 lBF = `0` Chr`7` : `24,240,165`	0.001	0.999	0.001
rs6977715 lBF = `0` Chr`7` : `154,169,002`	0.001	0.999	0.001
rs181328644 lBF = `0` Chr`7` : `34,899,414`	0.001	0.999	0.001
rs6973392 lBF = `0` Chr`7` : `89,060,733`	0.001	0.999	0.001
rs182858794 lBF = `0` Chr`7` : `93,981,552`	0.001	0.999	0.001
rs191729664 lBF = `0` Chr`7` : `125,652,599`	0.001	0.999	0.001
rs139557951 lBF = `0` Chr`7` : `151,748,474`	0.001	0.999	0.001
rs6593122 lBF = `0` Chr`7` : `54,181,932`	0.001	0.999	0.001
rs188061594 lBF = `0` Chr`7` : `151,729,217`	0.001	0.999	0.001
rs188324495 lBF = `0` Chr`7` : `7,195,467`	0.001	0.999	0.001
rs185205268 lBF = `0` Chr`7` : `144,075,117`	0.001	0.999	0.001
rs115605431 lBF = `0` Chr`7` : `3,221,648`	0.001	0.999	0.001
rs148376973 lBF = `0` Chr`7` : `151,739,270`	0.001	0.999	0.001
rs16882396 lBF = `0` Chr`7` : `140,888,321`	0.001	0.999	0.001
rs17159991 lBF = `0` Chr`7` : `31,242,470`	0.001	0.999	0.001
rs185746565 lBF = `0` Chr`7` : `135,260,049`	0.001	0.999	0.001
rs146622168 lBF = `0` Chr`7` : `34,937,537`	0.001	0.999	0.001
rs191979398 lBF = `0` Chr`7` : `94,008,007`	0.001	0.999	0.001
rs149069622 lBF = `0` Chr`7` : `151,749,259`	0.001	0.999	0.001
rs147962389 lBF = `0` Chr`7` : `151,730,891`	0.001	0.999	0.001
rs10428959 lBF = `0` Chr`7` : `111,677,906`	0.001	0.999	0.001
rs145460587 lBF = `0` Chr`7` : `53,441,569`	0.001	0.999	0.001
rs114174633 lBF = `0` Chr`7` : `151,706,189`	0.001	0.999	0.001
rs11564024 lBF = `0` Chr`7` : `27,335,561`	0.001	0.999	0.001
rs189909051 lBF = `0` Chr`7` : `151,731,803`	0.001	0.999	0.001
rs114659987 lBF = `0` Chr`7` : `51,094,963`	0.001	0.999	0.001
rs115744676 lBF = `0` Chr`7` : `94,061,404`	0.001	0.999	0.001
rs183600932 lBF = `0` Chr`7` : `11,058,396`	0.001	0.999	0.001
rs114004118 lBF = `0` Chr`7` : `151,742,102`	0.001	0.999	0.001
rs138896312 lBF = `0` Chr`7` : `53,900,123`	0.001	0.999	0.001
rs182033693 lBF = `0` Chr`7` : `70,622,427`	0.001	0.999	0.001
rs11980091 lBF = `-0.00834167` Chr`7` : `12,975,555`	0.001	0.999	0.000
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rs6959964 lBF = `-0.1702` Chr`7` : `68,905,738`	0.000	0.999	0.001
rs2329775 lBF = `0.0816178` Chr`7` : `40,481,812`	0.000	0.999	0.001
rs4149458 lBF = `0.0164746` Chr`7` : `65,709,777`	0.000	0.999	0.000
rs111576115 lBF = `-0.0054695` Chr`7` : `50,712,649`	0.000	0.999	0.000
rs117717824 lBF = `-0.00751255` Chr`7` : `113,989,202`	0.000	0.999	0.000
rs3750082 lBF = `-0.0190195` Chr`7` : `32,919,927`	0.000	0.999	0.000
rs17144465 lBF = `-0.0273042` Chr`7` : `21,504,427`	0.001	0.999	0.000
rs13227807 lBF = `-0.0372931` Chr`7` : `68,454,912`	0.000	0.999	0.000
rs62459614 lBF = `-0.0451921` Chr`7` : `70,587,145`	0.000	0.999	0.000
rs848353 lBF = `-0.0512944` Chr`7` : `108,548,660`	0.000	0.999	0.000
rs13224671 lBF = `-0.0702682` Chr`7` : `6,736,332`	0.000	0.999	0.000
rs11984145 lBF = `-0.0734862` Chr`7` : `38,835,035`	0.000	0.999	0.000
rs4730250 lBF = `-0.0912396` Chr`7` : `107,207,695`	0.000	0.999	0.000
rs59355858 lBF = `-0.121668` Chr`7` : `29,629,005`	0.001	0.999	0.000
rs2282930 lBF = `-0.129698` Chr`7` : `50,754,679`	0.001	0.999	0.000
rs1008126 lBF = `-0.153041` Chr`7` : `103,175,444`	0.001	0.999	0.000
rs12702661 lBF = `-0.167979` Chr`7` : `7,864,751`	0.000	0.999	0.001
rs3902751 lBF = `-0.189762` Chr`7` : `25,861,639`	0.000	0.999	0.001
rs12666280 lBF = `-0.20233` Chr`7` : `154,509,324`	0.001	0.999	0.000
rs4132568 lBF = `-0.221358` Chr`7` : `96,134,981`	0.000	0.999	0.001
rs2286276 lBF = `5.5098` Chr`7` : `72,987,354`	0.000	0.999	0.001
rs11984075 lBF = `4.21612` Chr`7` : `37,436,854`	0.000	0.999	0.000
rs1914395 lBF = `0.29075` Chr`7` : `71,839,408`	0.000	0.999	0.000
rs17173637 lBF = `0.239339` Chr`7` : `150,529,449`	0.001	0.999	0.000
rs75290158 lBF = `0.142828` Chr`7` : `96,652,459`	0.000	0.999	0.000
rs73079954 lBF = `0.0314781` Chr`7` : `24,746,536`	0.000	0.999	0.000
rs73302615 lBF = `-0.0111741` Chr`7` : `28,271,690`	0.000	0.999	0.000
rs59072263 lBF = `-0.0430064` Chr`7` : `8,152,067`	0.001	0.999	0.000
rs116864947 lBF = `-0.0517455` Chr`7` : `11,705,786`	0.000	0.999	0.000
rs10263087 lBF = `-0.053891` Chr`7` : `154,970,469`	0.000	0.999	0.000
rs76014476 lBF = `-0.0545394` Chr`7` : `105,107,249`	0.000	0.999	0.000
rs117898805 lBF = `-0.0576952` Chr`7` : `54,516,128`	0.000	0.999	0.000
rs2687481 lBF = `-0.0943169` Chr`7` : `125,869,122`	0.000	0.999	0.001
rs2391285 lBF = `-0.103435` Chr`7` : `26,581,796`	0.000	0.999	0.001
rs58880514 lBF = `-0.142747` Chr`7` : `70,404,837`	0.000	0.999	0.001
rs728115 lBF = `-0.143573` Chr`7` : `120,305,149`	0.000	0.999	0.001
rs2700987 lBF = `-0.158545` Chr`7` : `37,386,237`	0.000	0.999	0.001
rs12671878 lBF = `-0.163265` Chr`7` : `153,558,949`	0.001	0.999	0.000
rs1722141 lBF = `-0.204204` Chr`7` : `46,016,662`	0.000	0.999	0.000
rs12538707 lBF = `10.9268` Chr`7` : `87,124,268`	0.000	0.999	0.000
rs13232179 lBF = `0.365342` Chr`7` : `151,120,948`	0.001	0.999	0.000
rs730954 lBF = `0.150009` Chr`7` : `26,574,666`	0.000	0.999	0.001
rs11767851 lBF = `0.120678` Chr`7` : `8,183,347`	0.000	0.999	0.000
rs10952890 lBF = `0.0688403` Chr`7` : `86,355,215`	0.000	0.999	0.000
rs75404215 lBF = `0.00594102` Chr`7` : `15,472,901`	0.000	0.999	0.000
rs500454 lBF = `-0.00611272` Chr`7` : `80,799,834`	0.000	0.999	0.000
rs144872818 lBF = `-0.0433787` Chr`7` : `49,894,195`	0.000	0.999	0.000
rs142857449 lBF = `-0.0492114` Chr`7` : `85,048,380`	0.000	0.999	0.000
rs13230047 lBF = `-0.0503836` Chr`7` : `36,961,320`	0.000	0.999	0.000
rs1949829 lBF = `-0.0542322` Chr`7` : `51,537,887`	0.000	0.999	0.000
rs6977940 lBF = `-0.0616259` Chr`7` : `2,915,378`	0.000	0.999	0.000
rs117479459 lBF = `-0.0620414` Chr`7` : `3,459,194`	0.000	0.999	0.000
rs62471956 lBF = `-0.0642107` Chr`7` : `99,421,085`	0.000	0.999	0.000
rs79686877 lBF = `-0.0757188` Chr`7` : `6,417,836`	0.000	0.999	0.000
rs2390593 lBF = `-0.0864598` Chr`7` : `21,861,112`	0.000	0.999	0.000
rs17428471 lBF = `-0.0909279` Chr`7` : `27,337,867`	0.000	0.999	0.000
rs12702595 lBF = `-0.101209` Chr`7` : `7,259,270`	0.001	0.999	0.000
rs10259085 lBF = `-0.12421` Chr`7` : `7,268,431`	0.000	0.999	0.000
rs7786410 lBF = `-0.126562` Chr`7` : `55,922,323`	0.000	0.999	0.000
rs2237457 lBF = `-0.142759` Chr`7` : `50,726,144`	0.000	0.999	0.000
rs4142995 lBF = `-0.248419` Chr`7` : `17,919,258`	0.000	0.999	0.001
rs12539316 lBF = `6.11904` Chr`7` : `72,977,898`	0.000	0.999	0.001
rs12019361 lBF = `2.71491` Chr`7` : `87,573,647`	0.000	0.999	0.000
rs3914132 lBF = `0.134405` Chr`7` : `103,527,369`	0.000	0.999	0.000
rs11574703 lBF = `0.013491` Chr`7` : `80,286,908`	0.000	0.999	0.000
rs74349534 lBF = `0.00424947` Chr`7` : `83,764,113`	0.000	0.999	0.000
rs79698955 lBF = `0.00151791` Chr`7` : `105,272,676`	0.000	0.999	0.000
rs10248351 lBF = `-0.00273913` Chr`7` : `88,481,442`	0.000	0.999	0.000
rs115821935 lBF = `-0.00338049` Chr`7` : `90,738,831`	0.000	0.999	0.000
rs77261098 lBF = `-0.00971167` Chr`7` : `137,261,899`	0.000	0.999	0.000
rs76405237 lBF = `-0.0200769` Chr`7` : `140,970,819`	0.000	0.999	0.000
rs183820509 lBF = `-0.0211085` Chr`7` : `12,180,821`	0.000	0.999	0.000
rs117814736 lBF = `-0.0211679` Chr`7` : `12,180,757`	0.000	0.999	0.000
rs141958207 lBF = `-0.0211679` Chr`7` : `12,181,500`	0.000	0.999	0.000
rs1127065 lBF = `-0.0275865` Chr`7` : `44,259,871`	0.000	0.999	0.000
rs78895459 lBF = `-0.0310679` Chr`7` : `53,781,545`	0.000	0.999	0.000
rs142422697 lBF = `-0.0356206` Chr`7` : `49,965,291`	0.000	0.999	0.000
rs62477606 lBF = `-0.0405596` Chr`7` : `75,352,205`	0.000	0.999	0.000
rs7801534 lBF = `-0.0467784` Chr`7` : `49,329,680`	0.000	0.999	0.000
rs117877646 lBF = `-0.0578676` Chr`7` : `146,538,233`	0.000	0.999	0.000
rs740160 lBF = `-0.062903` Chr`7` : `98,957,880`	0.000	0.999	0.000
rs75016295 lBF = `-0.0711821` Chr`7` : `153,908,935`	0.000	0.999	0.000
rs62485867 lBF = `-0.0906021` Chr`7` : `103,647,344`	0.000	0.999	0.000
rs17428471 lBF = `-0.0921137` Chr`7` : `27,337,867`	0.000	0.999	0.000
rs6950451 lBF = `-0.102298` Chr`7` : `22,919,808`	0.000	0.999	0.001
rs6978712 lBF = `-0.133456` Chr`7` : `127,147,763`	0.000	0.999	0.000
rs11773349 lBF = `-0.135135` Chr`7` : `64,407,164`	0.000	0.999	0.001
rs7785730 lBF = `-0.152974` Chr`7` : `28,096,199`	0.000	0.999	0.000
rs7786877 lBF = `-0.18848` Chr`7` : `100,214,015`	0.001	0.999	0.000
rs11979158 lBF = `-0.202336` Chr`7` : `55,159,349`	0.000	0.999	0.000
rs713598 lBF = `-0.204595` Chr`7` : `141,673,345`	0.001	0.999	0.000
rs10254284 lBF = `2.85858` Chr`7` : `28,167,391`	0.000	0.999	0.001
rs765855 lBF = `0.446889` Chr`7` : `8,552,614`	0.001	0.999	0.000
rs878361 lBF = `0.241113` Chr`7` : `26,557,868`	0.000	0.999	0.000
rs77282735 lBF = `0.0905849` Chr`7` : `45,090,949`	0.000	0.999	0.000
rs1399090 lBF = `0.0362327` Chr`7` : `131,829,128`	0.000	0.999	0.000
rs6964235 lBF = `0.0158937` Chr`7` : `123,304,368`	0.000	0.999	0.000
rs117179684 lBF = `0.00244939` Chr`7` : `12,297,710`	0.000	0.999	0.000
rs528161076 lBF = `-0.0115897` Chr`7` : `4,827,514`	0.000	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	Heart valve problem/heart murmur
Nested terms	Aortic stenosis Aortic regurgitation / incompetence

Diagnostic term associations

Self-Reported Statistics (`SRS`)

Diagnostic term associations

Self-Reported Statistics (SRS)

Self-Reported Statistics (`SRS`)