TreeWAS – Aortic valve disease

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs1412444 lBF = `3.31381` Chr`10` : `91,002,927`	0.603	0.397	0.000
rs2250644 lBF = `3.43236` Chr`10` : `91,008,879`	0.598	0.402	0.000
rs1412444 lBF = `3.35516` Chr`10` : `91,002,927`	0.589	0.411	0.000
rs35632171 lBF = `1.83027` Chr`10` : `65,109,502`	0.576	0.424	0.000
rs1332329 lBF = `2.19523` Chr`10` : `91,003,419`	0.302	0.698	0.000
rs680091 lBF = `1.81194` Chr`10` : `44,738,932`	0.001	0.744	0.255
rs157079 lBF = `0.854686` Chr`10` : `106,058,778`	0.221	0.779	0.000
rs3135753 lBF = `1.18304` Chr`10` : `123,280,658`	0.161	0.839	0.000
rs12570824 lBF = `0.543523` Chr`10` : `65,730,654`	0.075	0.925	0.000
rs4752700 lBF = `0.551903` Chr`10` : `124,237,612`	0.064	0.936	0.000
rs1870634 lBF = `1.45108` Chr`10` : `44,480,811`	0.036	0.963	0.001
rs116369954 lBF = `0.808434` Chr`10` : `114,793,572`	0.021	0.978	0.000
rs2154401 lBF = `0.920226` Chr`10` : `44,655,275`	0.020	0.980	0.001
rs7069733 lBF = `7.47756` Chr`10` : `105,297,770`	0.016	0.984	0.000
rs1746048 lBF = `0.180546` Chr`10` : `44,775,824`	0.001	0.985	0.014
rs1746049 lBF = `0.150178` Chr`10` : `44,776,310`	0.001	0.985	0.014
rs76865013 lBF = `0.0522375` Chr`10` : `72,886,147`	0.015	0.985	0.000
rs192665745 lBF = `0.12204` Chr`10` : `26,627,381`	0.014	0.986	0.000
rs7068966 lBF = `0.142275` Chr`10` : `12,277,992`	0.000	0.990	0.010
rs501120 lBF = `0.125313` Chr`10` : `44,753,867`	0.001	0.990	0.009
rs11597473 lBF = `6.55248` Chr`10` : `105,319,041`	0.008	0.991	0.000
rs117352425 lBF = `0.0595776` Chr`10` : `5,115,032`	0.008	0.991	0.000
rs17854135 lBF = `1.83007` Chr`10` : `101,667,792`	0.000	0.991	0.008
rs192884195 lBF = `0.0820988` Chr`10` : `28,007,368`	0.008	0.992	0.000
rs7358151 lBF = `0.214149` Chr`10` : `28,017,572`	0.008	0.992	0.000
rs114765604 lBF = `0.0279298` Chr`10` : `135,287,931`	0.007	0.993	0.000
rs74606055 lBF = `0.128544` Chr`10` : `131,932,578`	0.006	0.993	0.000
rs11255615 lBF = `0.0394299` Chr`10` : `8,324,889`	0.006	0.994	0.000
rs11000019 lBF = `0.0553572` Chr`10` : `73,591,530`	0.006	0.994	0.000
rs11201253 lBF = `0.00203833` Chr`10` : `86,588,902`	0.005	0.994	0.000
rs12251332 lBF = `0.0602989` Chr`10` : `67,966,574`	0.005	0.995	0.000
rs6585424 lBF = `-0.019141` Chr`10` : `81,933,748`	0.005	0.995	0.000
rs11191593 lBF = `0.583824` Chr`10` : `104,939,215`	0.000	0.996	0.004
rs17639656 lBF = `-0.037585` Chr`10` : `119,493,705`	0.004	0.996	0.000
rs7094308 lBF = `-0.0424066` Chr`10` : `132,637,305`	0.004	0.996	0.000
rs79858930 lBF = `1.3229` Chr`10` : `83,047,434`	0.004	0.996	0.000
rs7907629 lBF = `0.0615594` Chr`10` : `105,549,440`	0.004	0.996	0.000
rs139479025 lBF = `0.0127221` Chr`10` : `71,880,301`	0.003	0.996	0.000
rs11191560 lBF = `0.578503` Chr`10` : `104,869,038`	0.000	0.996	0.003
rs10883832 lBF = `0.578503` Chr`10` : `104,871,279`	0.000	0.996	0.003
rs2986961 lBF = `-0.144413` Chr`10` : `30,087,359`	0.000	0.997	0.003
rs11191548 lBF = `0.712205` Chr`10` : `104,846,178`	0.000	0.997	0.003
rs4746853 lBF = `0.398543` Chr`10` : `64,181,219`	0.003	0.997	0.000
rs190780914 lBF = `0.0289979` Chr`10` : `84,949,895`	0.000	0.997	0.003
rs1171606 lBF = `-0.120183` Chr`10` : `61,434,519`	0.003	0.997	0.000
rs7907361 lBF = `-0.0775924` Chr`10` : `114,468,137`	0.003	0.997	0.000
rs11239177 lBF = `-0.196044` Chr`10` : `45,123,379`	0.001	0.997	0.002
rs12266096 lBF = `-0.1214` Chr`10` : `86,721,181`	0.000	0.997	0.003
rs12570188 lBF = `0.0215551` Chr`10` : `100,855,702`	0.002	0.997	0.000
rs2901286 lBF = `0.0767192` Chr`10` : `122,900,623`	0.000	0.997	0.002
rs11191454 lBF = `0.387814` Chr`10` : `104,660,004`	0.000	0.998	0.002
rs11592657 lBF = `-0.141651` Chr`10` : `128,790,443`	0.000	0.998	0.002
rs11187157 lBF = `-0.138774` Chr`10` : `94,502,244`	0.000	0.998	0.002
rs3739998 lBF = `-0.148591` Chr`10` : `30,316,072`	0.002	0.998	0.000
rs2487928 lBF = `-0.0319229` Chr`10` : `30,323,892`	0.002	0.998	0.000
rs73338448 lBF = `-0.00762369` Chr`10` : `99,882,156`	0.002	0.998	0.000
rs2485376 lBF = `2.51706` Chr`10` : `104,050,006`	0.002	0.998	0.000
rs1298908 lBF = `0.0323995` Chr`10` : `82,013,134`	0.002	0.998	0.000
rs7086888 lBF = `-0.100685` Chr`10` : `4,676,196`	0.002	0.998	0.000
rs12360000 lBF = `-0.12802` Chr`10` : `1,897,978`	0.002	0.998	0.000
rs12413409 lBF = `0.400829` Chr`10` : `104,719,096`	0.000	0.998	0.002
rs2995264 lBF = `0.892654` Chr`10` : `105,668,843`	0.000	0.998	0.002
rs10999409 lBF = `-0.178116` Chr`10` : `72,332,440`	0.002	0.998	0.000
rs11594258 lBF = `-0.157711` Chr`10` : `79,218,030`	0.000	0.998	0.002
rs10128264 lBF = `-0.0638458` Chr`10` : `80,959,973`	0.002	0.998	0.000
rs531676 lBF = `-0.113627` Chr`10` : `99,637,578`	0.002	0.998	0.000
rs11191580 lBF = `0.671808` Chr`10` : `104,906,211`	0.000	0.998	0.002
rs17601696 lBF = `-0.063933` Chr`10` : `123,120,036`	0.002	0.998	0.000
rs11191580 lBF = `0.707466` Chr`10` : `104,906,211`	0.000	0.998	0.002
rs16928705 lBF = `0.409518` Chr`10` : `73,095,793`	0.000	0.998	0.002
rs10508372 lBF = `0.013332` Chr`10` : `8,972,018`	0.002	0.998	0.000
rs1816002 lBF = `-0.103433` Chr`10` : `72,483,010`	0.002	0.998	0.000
rs11598874 lBF = `-0.0188847` Chr`10` : `39,006,198`	0.002	0.998	0.000
rs12356674 lBF = `0.345166` Chr`10` : `21,889,083`	0.002	0.998	0.000
rs718948 lBF = `-0.0638002` Chr`10` : `126,739,338`	0.002	0.998	0.000
rs2802369 lBF = `-0.0601824` Chr`10` : `80,960,828`	0.000	0.998	0.002
rs61829222 lBF = `-0.0290089` Chr`10` : `4,040,185`	0.001	0.998	0.000
rs869244 lBF = `-0.170273` Chr`10` : `112,909,105`	0.002	0.998	0.000
rs79458143 lBF = `-0.0253612` Chr`10` : `37,906,832`	0.001	0.998	0.000
rs190509410 lBF = `-0.00132675` Chr`10` : `63,626,494`	0.001	0.998	0.000
rs12772609 lBF = `-0.0112944` Chr`10` : `126,378,406`	0.001	0.998	0.000
rs4746003 lBF = `-0.107413` Chr`10` : `71,538,292`	0.000	0.998	0.001
rs2505083 lBF = `-0.0659218` Chr`10` : `30,335,122`	0.001	0.999	0.000
rs11012732 lBF = `0.456093` Chr`10` : `21,830,104`	0.001	0.999	0.000
rs56161216 lBF = `0.0070472` Chr`10` : `13,688,798`	0.001	0.999	0.000
rs7921536 lBF = `0.00282557` Chr`10` : `105,356,837`	0.001	0.999	0.000
rs1014246 lBF = `-0.0595137` Chr`10` : `118,466,042`	0.000	0.999	0.001
rs1908345 lBF = `-0.15235` Chr`10` : `57,710,042`	0.001	0.999	0.000
rs11252926 lBF = `0.385205` Chr`10` : `566,379`	0.000	0.999	0.001
rs2782980 lBF = `-0.100899` Chr`10` : `115,781,527`	0.001	0.999	0.000
rs7072122 lBF = `-0.0364799` Chr`10` : `45,034,672`	0.001	0.999	0.001
rs7092313 lBF = `-0.174741` Chr`10` : `10,689,602`	0.001	0.999	0.000
rs16917919 lBF = `-0.202384` Chr`10` : `19,160,029`	0.000	0.999	0.001
rs41322152 lBF = `0.00374427` Chr`10` : `72,040,805`	0.001	0.999	0.000
rs17152411 lBF = `-0.116892` Chr`10` : `126,649,516`	0.000	0.999	0.001
rs7915137 lBF = `-0.162861` Chr`10` : `84,870,076`	0.000	0.999	0.001
rs1148233 lBF = `0.00217451` Chr`10` : `31,461,599`	0.001	0.999	0.000
rs12248541 lBF = `0.00173949` Chr`10` : `105,390,343`	0.001	0.999	0.000
rs11018023 lBF = `-0.130752` Chr`10` : `133,330,026`	0.000	0.999	0.001
rs78737652 lBF = `-0.0215969` Chr`10` : `55,897,071`	0.000	0.999	0.001
rs7085142 lBF = `-0.181708` Chr`10` : `122,939,374`	0.000	0.999	0.001
rs932764 lBF = `-0.245904` Chr`10` : `95,895,940`	0.001	0.999	0.000
rs7903144 lBF = `-0.00190123` Chr`10` : `22,057,405`	0.000	0.999	0.001
rs10905099 lBF = `-0.0952401` Chr`10` : `7,089,016`	0.000	0.999	0.001
rs2137920 lBF = `-0.137139` Chr`10` : `50,229,638`	0.000	0.999	0.001
rs1993484 lBF = `0.821412` Chr`10` : `82,222,698`	0.001	0.999	0.000
rs7919823 lBF = `0.00794176` Chr`10` : `22,036,491`	0.000	0.999	0.001
rs181778161 lBF = `0.0015845` Chr`10` : `91,691,500`	0.001	0.999	0.000
rs11239187 lBF = `-0.193339` Chr`10` : `45,133,277`	0.000	0.999	0.001
rs7088203 lBF = `0.0284132` Chr`10` : `73,946,588`	0.001	0.999	0.000
rs61852012 lBF = `-0.151397` Chr`10` : `73,411,113`	0.000	0.999	0.001
rs603424 lBF = `2.44385` Chr`10` : `102,075,479`	0.001	0.999	0.000
rs7100689 lBF = `0.615603` Chr`10` : `82,222,178`	0.001	0.999	0.000
rs115882204 lBF = `0.00589499` Chr`10` : `28,590,383`	0.001	0.999	0.001
rs11009175 lBF = `-0.170597` Chr`10` : `33,294,775`	0.000	0.999	0.001
rs9420907 lBF = `0.242443` Chr`10` : `105,676,465`	0.001	0.999	0.000
rs6602364 lBF = `3.11849` Chr`10` : `6,038,853`	0.000	0.999	0.001
rs9943451 lBF = `0.0129441` Chr`10` : `7,070,570`	0.000	0.999	0.001
rs181715218 lBF = `-0.0160111` Chr`10` : `81,185,314`	0.001	0.999	0.000
rs1930170 lBF = `-0.107988` Chr`10` : `56,217,752`	0.000	0.999	0.001
rs2944542 lBF = `2.84414` Chr`10` : `64,369,999`	0.001	0.999	0.000
rs7895372 lBF = `0.0008572` Chr`10` : `15,719,621`	0.001	0.999	0.000
rs61458523 lBF = `0.0005677` Chr`10` : `60,668,571`	0.000	0.999	0.001
rs10884482 lBF = `-0.0094195` Chr`10` : `109,380,264`	0.000	0.999	0.001
rs11250714 lBF = `-0.121713` Chr`10` : `1,702,581`	0.000	0.999	0.001
rs786870 lBF = `-0.219861` Chr`10` : `26,774,694`	0.001	0.999	0.000
rs10761785 lBF = `1.97697` Chr`10` : `65,318,766`	0.001	0.999	0.000
rs7904655 lBF = `0.00151214` Chr`10` : `22,838,726`	0.001	0.999	0.000
rs515910 lBF = `-0.18658` Chr`10` : `105,966,404`	0.000	0.999	0.001
rs150400940 lBF = `0.00031309` Chr`10` : `113,810,429`	0.001	0.999	0.000
rs12773846 lBF = `-0.0814312` Chr`10` : `126,275,914`	0.001	0.999	0.000
rs7897969 lBF = `-0.130657` Chr`10` : `125,929,799`	0.000	0.999	0.001
rs3981351 lBF = `-0.184357` Chr`10` : `115,515,120`	0.001	0.999	0.000
rs1243180 lBF = `0.703477` Chr`10` : `21,915,619`	0.001	0.999	0.000
rs11017328 lBF = `0.0168145` Chr`10` : `132,347,100`	0.000	0.999	0.001
rs12252129 lBF = `0.00007109` Chr`10` : `50,103,072`	0.000	0.999	0.001
rs1612122 lBF = `-0.147745` Chr`10` : `29,291,898`	0.001	0.999	0.000
rs7072574 lBF = `0.0406593` Chr`10` : `96,036,306`	0.001	0.999	0.000
rs114154155 lBF = `0.00066648` Chr`10` : `63,185,662`	0.001	0.999	0.000
rs10508343 lBF = `0.00012975` Chr`10` : `8,150,713`	0.001	0.999	0.000
rs3750716 lBF = `0.0000115` Chr`10` : `101,816,863`	0.001	0.999	0.000
rs117260820 lBF = `0` Chr`10` : `102,048,643`	0.001	0.999	0.001
rs190045766 lBF = `0` Chr`10` : `120,643,886`	0.001	0.999	0.001
rs181666690 lBF = `0` Chr`10` : `28,852,022`	0.001	0.999	0.001
rs76409888 lBF = `0` Chr`10` : `73,723,956`	0.001	0.999	0.001
rs184737911 lBF = `0` Chr`10` : `88,431,292`	0.001	0.999	0.001
rs78627331 lBF = `0` Chr`10` : `94,812,254`	0.001	0.999	0.001
rs185636671 lBF = `0` Chr`10` : `135,172,794`	0.001	0.999	0.001
rs76850691 lBF = `0` Chr`10` : `101,157,438`	0.001	0.999	0.001
rs185671464 lBF = `0` Chr`10` : `54,486,920`	0.001	0.999	0.001
rs142973438 lBF = `0` Chr`10` : `95,315,999`	0.001	0.999	0.001
rs180858466 lBF = `0` Chr`10` : `38,761,238`	0.001	0.999	0.001
rs114088342 lBF = `0` Chr`10` : `35,918,232`	0.001	0.999	0.001
rs140682412 lBF = `0` Chr`10` : `89,332,706`	0.001	0.999	0.001
rs79105493 lBF = `0` Chr`10` : `95,475,354`	0.001	0.999	0.001
rs12245299 lBF = `0` Chr`10` : `55,913,700`	0.001	0.999	0.001
rs143988467 lBF = `0` Chr`10` : `95,317,394`	0.001	0.999	0.001
rs183323229 lBF = `0` Chr`10` : `33,168,215`	0.001	0.999	0.001
rs182344828 lBF = `0` Chr`10` : `54,593,326`	0.001	0.999	0.001
rs182554582 lBF = `0` Chr`10` : `88,194,959`	0.001	0.999	0.001
rs58600253 lBF = `0` Chr`10` : `64,507,904`	0.001	0.999	0.001
rs7072776 lBF = `0` Chr`10` : `22,032,942`	0.001	0.999	0.001
rs77040403 lBF = `0` Chr`10` : `71,640,838`	0.001	0.999	0.001
rs144473309 lBF = `0` Chr`10` : `77,129,161`	0.001	0.999	0.001
rs188724679 lBF = `0` Chr`10` : `135,224,855`	0.001	0.999	0.001
rs12263766 lBF = `0` Chr`10` : `9,996,990`	0.001	0.999	0.001
rs115553536 lBF = `0` Chr`10` : `31,981,385`	0.001	0.999	0.001
rs4750829 lBF = `0` Chr`10` : `132,547,261`	0.001	0.999	0.001
rs10796051 lBF = `0` Chr`10` : `13,310,071`	0.001	0.999	0.001
rs190671939 lBF = `0` Chr`10` : `134,909,987`	0.001	0.999	0.001
rs4748185 lBF = `-0.00020623` Chr`10` : `15,654,887`	0.001	0.999	0.000
rs11199254 lBF = `-0.00120086` Chr`10` : `122,043,489`	0.000	0.999	0.001
rs147729365 lBF = `-0.00157561` Chr`10` : `12,482,907`	0.001	0.999	0.000
rs7077164 lBF = `-0.139655` Chr`10` : `71,583,198`	0.000	0.999	0.001
rs1471384 lBF = `-0.177543` Chr`10` : `67,964,373`	0.000	0.999	0.001
rs146091982 lBF = `-0.00014096` Chr`10` : `95,659,958`	0.000	0.999	0.001
rs12247397 lBF = `-0.00025744` Chr`10` : `9,363,877`	0.001	0.999	0.000
rs384627 lBF = `-0.00045705` Chr`10` : `119,336,746`	0.000	0.999	0.001
rs2456721 lBF = `-0.100998` Chr`10` : `121,665,773`	0.000	0.999	0.001
rs1250550 lBF = `4.28518` Chr`10` : `81,060,317`	0.000	0.999	0.001
rs7071247 lBF = `0.167152` Chr`10` : `105,257,786`	0.001	0.999	0.000
rs722258 lBF = `0.0271319` Chr`10` : `23,369,421`	0.000	0.999	0.001
rs117607728 lBF = `0.0199376` Chr`10` : `96,058,636`	0.001	0.999	0.000
rs7098187 lBF = `0.00140433` Chr`10` : `15,538,383`	0.001	0.999	0.000
rs4838508 lBF = `0.00096585` Chr`10` : `50,561,507`	0.000	0.999	0.001
rs1397615 lBF = `-0.00032935` Chr`10` : `120,966,339`	0.000	0.999	0.001
rs143362648 lBF = `-0.00047122` Chr`10` : `21,694,219`	0.001	0.999	0.000
rs2799573 lBF = `-0.151267` Chr`10` : `18,601,928`	0.000	0.999	0.001
rs12722515 lBF = `3.9144` Chr`10` : `6,081,230`	0.000	0.999	0.001
rs2388328 lBF = `-0.00047877` Chr`10` : `131,234,372`	0.001	0.999	0.000
rs192858301 lBF = `-0.00070322` Chr`10` : `24,071,006`	0.001	0.999	0.000
rs11204213 lBF = `-0.00076964` Chr`10` : `48,388,228`	0.001	0.999	0.000
rs114540395 lBF = `-0.110237` Chr`10` : `103,479,062`	0.000	0.999	0.001
rs12764441 lBF = `-0.167982` Chr`10` : `72,691,651`	0.000	0.999	0.001
rs12722561 lBF = `4.0736` Chr`10` : `6,069,893`	0.000	0.999	0.001
rs10822184 lBF = `2.04881` Chr`10` : `65,337,153`	0.001	0.999	0.000
rs11195062 lBF = `0.147853` Chr`10` : `112,036,975`	0.001	0.999	0.000
rs4750535 lBF = `0.00059597` Chr`10` : `14,633,024`	0.001	0.999	0.000
rs10822136 lBF = `-0.0380565` Chr`10` : `64,872,411`	0.001	0.999	0.000
rs1444418 lBF = `-0.097074` Chr`10` : `64,560,470`	0.001	0.999	0.000
rs10509373 lBF = `0.0273316` Chr`10` : `78,157,572`	0.000	0.999	0.001
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rs768606 lBF = `0.0174336` Chr`10` : `9,277,525`	0.000	0.999	0.000
rs117405975 lBF = `-0.00675985` Chr`10` : `131,698,562`	0.000	0.999	0.000
rs4748741 lBF = `-0.00811486` Chr`10` : `21,259,144`	0.000	0.999	0.000
rs41274622 lBF = `-0.0158907` Chr`10` : `55,570,347`	0.000	0.999	0.000
rs28360899 lBF = `-0.0841748` Chr`10` : `125,772,237`	0.000	0.999	0.000
rs1867982 lBF = `-0.103944` Chr`10` : `73,527,047`	0.001	0.999	0.000
rs3847375 lBF = `-0.122921` Chr`10` : `21,567,565`	0.001	0.999	0.000
rs11596483 lBF = `-0.162139` Chr`10` : `124,037,599`	0.000	0.999	0.000
rs28643277 lBF = `-0.166166` Chr`10` : `15,600,671`	0.001	0.999	0.000
rs117352156 lBF = `-0.169031` Chr`10` : `29,246,205`	0.001	0.999	0.000
rs10995439 lBF = `-0.18392` Chr`10` : `64,866,912`	0.000	0.999	0.001
rs2981582 lBF = `-0.186202` Chr`10` : `123,352,317`	0.001	0.999	0.000
rs2420903 lBF = `-0.212407` Chr`10` : `122,802,506`	0.001	0.999	0.000
rs703980 lBF = `0.711984` Chr`10` : `80,943,841`	0.001	0.999	0.000
rs1466576 lBF = `0.433382` Chr`10` : `72,688,371`	0.000	0.999	0.001
rs12775535 lBF = `0.280845` Chr`10` : `25,918,879`	0.000	0.999	0.000
rs7078209 lBF = `0.148395` Chr`10` : `124,860,026`	0.000	0.999	0.001
rs72793138 lBF = `0.0875183` Chr`10` : `55,480,888`	0.000	0.999	0.000
rs3818285 lBF = `0.0488798` Chr`10` : `111,635,212`	0.000	0.999	0.000
rs11816631 lBF = `0.0265971` Chr`10` : `99,562,572`	0.000	0.999	0.000
rs1250307 lBF = `0.0151741` Chr`10` : `31,495,974`	0.000	0.999	0.000
rs2484992 lBF = `0.0131095` Chr`10` : `31,512,098`	0.000	0.999	0.000
rs10763170 lBF = `0.00259041` Chr`10` : `56,777,024`	0.001	0.999	0.000
rs10788575 lBF = `-0.00398497` Chr`10` : `89,768,584`	0.001	0.999	0.000
rs61856137 lBF = `-0.00862707` Chr`10` : `5,087,978`	0.000	0.999	0.001
rs1890185 lBF = `-0.0298855` Chr`10` : `104,748,718`	0.001	0.999	0.000
rs117841971 lBF = `-0.0354099` Chr`10` : `80,699,184`	0.000	0.999	0.000
rs10883817 lBF = `-0.0370203` Chr`10` : `104,755,431`	0.001	0.999	0.000
rs7920888 lBF = `-0.0531811` Chr`10` : `90,818,377`	0.001	0.999	0.000
rs11014306 lBF = `-0.0792848` Chr`10` : `25,224,462`	0.000	0.999	0.001
rs10466239 lBF = `-0.105639` Chr`10` : `43,849,827`	0.000	0.999	0.001
rs7081678 lBF = `-0.124476` Chr`10` : `31,990,623`	0.000	0.999	0.000
rs1530440 lBF = `-0.131413` Chr`10` : `63,524,591`	0.000	0.999	0.001
rs3135758 lBF = `-0.1335` Chr`10` : `123,277,869`	0.000	0.999	0.000
rs2274223 lBF = `-0.144785` Chr`10` : `96,066,341`	0.000	0.999	0.001
rs2370759 lBF = `-0.146984` Chr`10` : `32,634,972`	0.000	0.999	0.001
rs17455577 lBF = `-0.215213` Chr`10` : `100,165,997`	0.000	0.999	0.000
rs7916868 lBF = `2.04475` Chr`10` : `64,988,931`	0.001	0.999	0.000
rs10997517 lBF = `0.591474` Chr`10` : `68,879,803`	0.000	0.999	0.000
rs77329626 lBF = `0.133897` Chr`10` : `61,664,195`	0.000	0.999	0.000
rs2017305 lBF = `0.068966` Chr`10` : `70,712,062`	0.000	0.999	0.000
rs1472750 lBF = `0.0478805` Chr`10` : `115,235,114`	0.000	0.999	0.000
rs12220014 lBF = `0.0271008` Chr`10` : `30,576,938`	0.000	0.999	0.000
rs7077335 lBF = `0.025518` Chr`10` : `6,315,794`	0.000	0.999	0.000
rs41284366 lBF = `0.0035851` Chr`10` : `118,187,444`	0.000	0.999	0.000
rs7902334 lBF = `-0.00840424` Chr`10` : `12,645,941`	0.000	0.999	0.000
rs72801595 lBF = `-0.0177759` Chr`10` : `70,718,527`	0.000	0.999	0.000
rs563507 lBF = `-0.0195805` Chr`10` : `34,817,988`	0.000	0.999	0.000
rs79619559 lBF = `-0.0283817` Chr`10` : `2,776,698`	0.000	0.999	0.000
rs2228638 lBF = `-0.0417728` Chr`10` : `33,475,282`	0.000	0.999	0.000
rs17267338 lBF = `-0.051656` Chr`10` : `114,388,272`	0.000	0.999	0.000
rs77268492 lBF = `-0.0585871` Chr`10` : `95,315,221`	0.000	0.999	0.000
rs1025561 lBF = `-0.0934283` Chr`10` : `80,387,684`	0.001	0.999	0.000
rs10458771 lBF = `-0.104585` Chr`10` : `88,162,238`	0.001	0.999	0.000
rs7078160 lBF = `-0.109793` Chr`10` : `118,827,560`	0.000	0.999	0.000
rs11006253 lBF = `-0.112839` Chr`10` : `60,519,448`	0.000	0.999	0.001
rs10825036 lBF = `-0.138929` Chr`10` : `55,266,231`	0.000	0.999	0.000
rs4363506 lBF = `-0.200435` Chr`10` : `129,274,503`	0.001	0.999	0.000
rs3750817 lBF = `-0.21639` Chr`10` : `123,332,577`	0.001	0.999	0.000
rs61839660 lBF = `11.4863` Chr`10` : `6,094,697`	0.000	0.999	0.000
rs4406737 lBF = `2.12242` Chr`10` : `90,759,724`	0.000	0.999	0.001
rs11191416 lBF = `0.697909` Chr`10` : `104,604,916`	0.000	0.999	0.000
rs7086627 lBF = `0.451984` Chr`10` : `82,220,597`	0.001	0.999	0.000
rs55783015 lBF = `0.169021` Chr`10` : `127,276,562`	0.000	0.999	0.000
rs17747401 lBF = `0.103292` Chr`10` : `76,400,164`	0.000	0.999	0.000
rs2071426 lBF = `0.0743475` Chr`10` : `96,828,323`	0.000	0.999	0.000
rs75703265 lBF = `0.0368948` Chr`10` : `58,800,953`	0.000	0.999	0.000
rs12573070 lBF = `0.0293604` Chr`10` : `15,085,073`	0.000	0.999	0.000
rs74146301 lBF = `0.00873668` Chr`10` : `76,990,646`	0.000	0.999	0.000
rs41314988 lBF = `0.00790507` Chr`10` : `72,640,041`	0.000	0.999	0.000
rs3812645 lBF = `0.00356454` Chr`10` : `87,489,317`	0.000	0.999	0.000
rs117256623 lBF = `-0.00246165` Chr`10` : `123,454,174`	0.000	0.999	0.000
rs150663673 lBF = `-0.00485041` Chr`10` : `25,407,209`	0.000	0.999	0.000
rs2790232 lBF = `-0.00624085` Chr`10` : `59,985,671`	0.000	0.999	0.000
rs61860854 lBF = `-0.0128051` Chr`10` : `61,339,893`	0.000	0.999	0.000
rs113793030 lBF = `-0.013995` Chr`10` : `72,046,860`	0.000	0.999	0.000
rs79538733 lBF = `-0.0326596` Chr`10` : `71,500,897`	0.000	0.999	0.000
rs2228638 lBF = `-0.0359116` Chr`10` : `33,475,282`	0.000	0.999	0.000
rs113603971 lBF = `-0.0367945` Chr`10` : `13,850,836`	0.000	0.999	0.000
rs74122244 lBF = `-0.0379289` Chr`10` : `14,402,332`	0.000	0.999	0.000
rs6585436 lBF = `-0.0494625` Chr`10` : `119,210,375`	0.000	0.999	0.000
rs10510138 lBF = `-0.0523304` Chr`10` : `126,438,019`	0.000	0.999	0.000
rs74122981 lBF = `-0.0558329` Chr`10` : `14,790,203`	0.000	0.999	0.000
rs116860688 lBF = `-0.0618909` Chr`10` : `106,157,002`	0.000	0.999	0.000
rs7073278 lBF = `-0.067018` Chr`10` : `13,859,897`	0.000	0.999	0.000
rs17497526 lBF = `-0.0686921` Chr`10` : `71,580,120`	0.000	0.999	0.000
rs2387326 lBF = `-0.0777482` Chr`10` : `129,933,456`	0.000	0.999	0.000
rs2593149 lBF = `-0.0930258` Chr`10` : `80,390,267`	0.000	0.999	0.000
rs2153299 lBF = `-0.121301` Chr`10` : `28,752,106`	0.000	0.999	0.001
rs3824789 lBF = `-0.15347` Chr`10` : `98,800,099`	0.001	0.999	0.000
rs10826545 lBF = `-0.164258` Chr`10` : `29,236,395`	0.000	0.999	0.000
rs188370812 lBF = `-0.175241` Chr`10` : `29,246,249`	0.000	0.999	0.000
rs192649950 lBF = `-0.178637` Chr`10` : `29,246,250`	0.000	0.999	0.000
rs12414342 lBF = `-0.186247` Chr`10` : `133,289,905`	0.001	0.999	0.000
rs1149933 lBF = `-0.205382` Chr`10` : `9,193,901`	0.000	0.999	0.000
rs12413578 lBF = `44.9786` Chr`10` : `9,049,253`	0.000	0.999	0.000
rs7903146 lBF = `33.6503` Chr`10` : `114,758,349`	0.000	0.999	0.000
rs7903146 lBF = `32.159` Chr`10` : `114,758,349`	0.000	0.999	0.000
rs16926246 lBF = `2.86359` Chr`10` : `71,093,392`	0.000	0.999	0.000
rs10822013 lBF = `0.825408` Chr`10` : `64,251,977`	0.000	0.999	0.000
rs10822013 lBF = `0.744489` Chr`10` : `64,251,977`	0.000	0.999	0.000
rs10995092 lBF = `0.318616` Chr`10` : `64,001,700`	0.000	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	Heart valve problem/heart murmur
Nested terms	Aortic stenosis Aortic regurgitation / incompetence

Diagnostic term associations

Self-Reported Statistics (`SRS`)

Diagnostic term associations

Self-Reported Statistics (SRS)

Self-Reported Statistics (`SRS`)