TreeWAS – Aortic valve disease

Variant effects

Click on a variant to see its association results.

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Genome-wide Chromosomes: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Results table

Variant	Risk posterior probability	No effect posterior probability	Protective posterior probability
rs115849089 lBF = `14.378` Chr`8` : `19,912,370`	0.000	0.162	0.838
rs15285 lBF = `21.5663` Chr`8` : `19,824,667`	0.000	0.197	0.802
rs15285 lBF = `20.8189` Chr`8` : `19,824,667`	0.000	0.203	0.797
rs13702 lBF = `20.6198` Chr`8` : `19,824,492`	0.000	0.206	0.794
rs10105606 lBF = `7.63468` Chr`8` : `19,827,848`	0.000	0.209	0.791
rs326 lBF = `18.2196` Chr`8` : `19,819,439`	0.000	0.244	0.756
rs1059611 lBF = `11.4313` Chr`8` : `19,824,563`	0.000	0.249	0.751
rs301 lBF = `13.2977` Chr`8` : `19,816,934`	0.000	0.255	0.745
rs331 lBF = `18.3037` Chr`8` : `19,820,405`	0.000	0.256	0.744
rs295 lBF = `13.9577` Chr`8` : `19,816,238`	0.000	0.257	0.743
rs1441756 lBF = `17.8944` Chr`8` : `19,868,386`	0.000	0.269	0.731
rs2083637 lBF = `18.6414` Chr`8` : `19,865,175`	0.000	0.278	0.722
rs325 lBF = `11.3351` Chr`8` : `19,819,328`	0.000	0.319	0.681
rs7841189 lBF = `10.6036` Chr`8` : `19,845,376`	0.000	0.338	0.662
rs17410962 lBF = `10.7017` Chr`8` : `19,848,080`	0.000	0.339	0.661
rs10096633 lBF = `11.5201` Chr`8` : `19,830,921`	0.000	0.339	0.661
rs328 lBF = `11.3674` Chr`8` : `19,819,724`	0.000	0.348	0.652
rs7016880 lBF = `9.81699` Chr`8` : `19,876,746`	0.000	0.387	0.613
rs12678919 lBF = `10.111` Chr`8` : `19,844,222`	0.000	0.399	0.600
rs17482753 lBF = `11.2737` Chr`8` : `19,832,646`	0.000	0.424	0.575
rs10503669 lBF = `9.47664` Chr`8` : `19,847,690`	0.000	0.445	0.554
rs9644568 lBF = `9.46038` Chr`8` : `19,928,582`	0.000	0.448	0.552
rs17091905 lBF = `9.01702` Chr`8` : `19,849,757`	0.000	0.473	0.527
rs2197089 lBF = `1.46408` Chr`8` : `19,826,373`	0.000	0.493	0.507
rs79236614 lBF = `9.53047` Chr`8` : `19,860,460`	0.000	0.518	0.481
rs264 lBF = `3.99567` Chr`8` : `19,813,180`	0.000	0.620	0.379
rs268 lBF = `1.6212` Chr`8` : `19,813,529`	0.364	0.636	0.000
rs17250031 lBF = `1.14225` Chr`8` : `75,077,959`	0.294	0.706	0.000
rs2126259 lBF = `1.7955` Chr`8` : `9,185,146`	0.232	0.768	0.000
rs1461729 lBF = `1.91121` Chr`8` : `9,187,242`	0.222	0.778	0.000
rs112875651 lBF = `72.444` Chr`8` : `126,506,694`	0.001	0.796	0.203
rs2001846 lBF = `62.3846` Chr`8` : `126,478,450`	0.001	0.807	0.193
rs2001945 lBF = `62.017` Chr`8` : `126,477,978`	0.001	0.808	0.191
rs17321515 lBF = `59.7582` Chr`8` : `126,486,409`	0.001	0.818	0.181
rs6982636 lBF = `58.9022` Chr`8` : `126,479,315`	0.001	0.820	0.179
rs2954029 lBF = `59.4117` Chr`8` : `126,490,972`	0.001	0.829	0.170
rs4841132 lBF = `1.86188` Chr`8` : `9,183,596`	0.166	0.834	0.000
rs2954022 lBF = `60.0986` Chr`8` : `126,482,621`	0.002	0.845	0.154
rs2954021 lBF = `65.5349` Chr`8` : `126,482,077`	0.001	0.846	0.153
rs4240624 lBF = `2.15466` Chr`8` : `9,184,231`	0.144	0.856	0.000
rs2169387 lBF = `1.5972` Chr`8` : `9,181,395`	0.127	0.872	0.000
rs9987289 lBF = `2.28852` Chr`8` : `9,183,358`	0.119	0.881	0.000
rs2954038 lBF = `51.8508` Chr`8` : `126,507,389`	0.105	0.894	0.001
rs2954031 lBF = `53.2493` Chr`8` : `126,491,733`	0.002	0.910	0.089
rs2954038 lBF = `51.3752` Chr`8` : `126,507,389`	0.001	0.922	0.077
rs2980879 lBF = `43.4452` Chr`8` : `126,481,475`	0.001	0.932	0.067
rs1441759 lBF = `0.485687` Chr`8` : `19,865,563`	0.061	0.939	0.000
rs72659626 lBF = `0.238942` Chr`8` : `72,920,433`	0.044	0.956	0.000
rs77616023 lBF = `0.292524` Chr`8` : `57,336,601`	0.041	0.958	0.000
rs2954033 lBF = `44.9208` Chr`8` : `126,493,746`	0.001	0.960	0.040
rs6601299 lBF = `0.672602` Chr`8` : `9,184,691`	0.038	0.962	0.000
rs191939331 lBF = `0.182487` Chr`8` : `84,717,650`	0.030	0.970	0.000
rs2954026 lBF = `43.8924` Chr`8` : `126,484,526`	0.000	0.971	0.028
rs80029792 lBF = `0.150517` Chr`8` : `134,781,276`	0.028	0.972	0.000
rs7012814 lBF = `3.82703` Chr`8` : `9,173,358`	0.026	0.974	0.000
rs74566133 lBF = `0.124231` Chr`8` : `134,778,342`	0.023	0.977	0.000
rs75835816 lBF = `0.162558` Chr`8` : `19,885,513`	0.009	0.991	0.000
rs4921914 lBF = `8.55574` Chr`8` : `18,272,438`	0.000	0.992	0.008
rs4342585 lBF = `0.520569` Chr`8` : `74,467,504`	0.007	0.993	0.000
rs1495743 lBF = `7.59778` Chr`8` : `18,273,300`	0.000	0.993	0.007
rs10503672 lBF = `-0.0520588` Chr`8` : `19,987,703`	0.000	0.994	0.006
rs6995588 lBF = `0.0901814` Chr`8` : `61,003,897`	0.005	0.994	0.000
rs2460905 lBF = `0.444699` Chr`8` : `12,834,600`	0.005	0.995	0.000
rs140707667 lBF = `0.0245574` Chr`8` : `84,028,528`	0.005	0.995	0.000
rs73225862 lBF = `0.0556736` Chr`8` : `22,050,584`	0.004	0.995	0.000
rs186868868 lBF = `0.151835` Chr`8` : `19,863,803`	0.004	0.995	0.000
rs1495741 lBF = `8.15044` Chr`8` : `18,272,881`	0.000	0.995	0.004
rs184060364 lBF = `0.0208941` Chr`8` : `84,120,968`	0.004	0.996	0.000
rs35246381 lBF = `8.27142` Chr`8` : `18,272,535`	0.000	0.996	0.004
rs4921915 lBF = `8.21409` Chr`8` : `18,272,466`	0.000	0.996	0.004
rs1566080 lBF = `-0.190893` Chr`8` : `142,556,805`	0.000	0.996	0.004
rs4921913 lBF = `8.14228` Chr`8` : `18,272,377`	0.000	0.996	0.004
rs12677663 lBF = `-0.232052` Chr`8` : `74,007,347`	0.003	0.997	0.000
rs7006687 lBF = `-0.209612` Chr`8` : `18,233,582`	0.003	0.997	0.000
rs78586881 lBF = `0.0766381` Chr`8` : `37,144,739`	0.003	0.997	0.000
rs1208 lBF = `-0.161433` Chr`8` : `18,258,316`	0.000	0.997	0.003
rs11782819 lBF = `-0.148982` Chr`8` : `10,334,781`	0.003	0.997	0.000
rs4875102 lBF = `-0.130188` Chr`8` : `4,284,692`	0.003	0.997	0.000
rs969599 lBF = `0.258222` Chr`8` : `18,424,731`	0.002	0.997	0.000
rs4281086 lBF = `-0.132765` Chr`8` : `10,352,308`	0.000	0.997	0.003
rs7826834 lBF = `0.013083` Chr`8` : `62,401,962`	0.002	0.998	0.000
rs2449215 lBF = `-0.153719` Chr`8` : `3,488,338`	0.000	0.998	0.002
rs80343479 lBF = `0.069029` Chr`8` : `16,386,058`	0.002	0.998	0.000
rs13272568 lBF = `-0.176122` Chr`8` : `79,034,459`	0.002	0.998	0.000
rs7832552 lBF = `-0.129028` Chr`8` : `110,115,676`	0.000	0.998	0.002
rs2720508 lBF = `0.0236256` Chr`8` : `17,329,827`	0.000	0.998	0.001
rs721399 lBF = `2.3774` Chr`8` : `18,259,366`	0.000	0.998	0.001
rs117500008 lBF = `0.0645869` Chr`8` : `101,671,045`	0.001	0.998	0.000
rs311392 lBF = `-0.155146` Chr`8` : `55,084,782`	0.000	0.998	0.002
rs17739794 lBF = `-0.248139` Chr`8` : `812,946`	0.000	0.998	0.002
rs17658378 lBF = `-0.0158023` Chr`8` : `116,394,075`	0.001	0.998	0.000
rs4738393 lBF = `-0.119248` Chr`8` : `56,599,777`	0.000	0.998	0.002
rs187162159 lBF = `0.0140538` Chr`8` : `25,111,606`	0.001	0.998	0.000
rs116951791 lBF = `-0.0128998` Chr`8` : `93,219,721`	0.001	0.998	0.000
rs17349258 lBF = `-0.207212` Chr`8` : `4,841,024`	0.002	0.998	0.000
rs118124984 lBF = `0.00457754` Chr`8` : `106,184,779`	0.001	0.998	0.000
rs12549902 lBF = `-0.13947` Chr`8` : `41,509,259`	0.000	0.998	0.002
rs112767144 lBF = `0.00042324` Chr`8` : `134,263,916`	0.001	0.998	0.000
rs11989868 lBF = `-0.149278` Chr`8` : `14,550,156`	0.000	0.998	0.002
rs150281976 lBF = `0.00568202` Chr`8` : `25,131,459`	0.001	0.998	0.000
rs12543318 lBF = `-0.102123` Chr`8` : `88,868,340`	0.000	0.998	0.001
rs67455183 lBF = `0.0143785` Chr`8` : `10,145,925`	0.000	0.999	0.001
rs188420713 lBF = `0.00750812` Chr`8` : `37,134,189`	0.001	0.999	0.000
rs72657970 lBF = `0.00732974` Chr`8` : `72,808,087`	0.001	0.999	0.000
rs7386474 lBF = `-0.107319` Chr`8` : `142,359,550`	0.001	0.999	0.000
rs980238 lBF = `-0.117732` Chr`8` : `4,282,618`	0.001	0.999	0.000
rs72663955 lBF = `-0.0421191` Chr`8` : `71,139,330`	0.000	0.999	0.001
rs10875469 lBF = `-0.156564` Chr`8` : `142,333,425`	0.001	0.999	0.000
rs2360806 lBF = `-0.0682882` Chr`8` : `53,125,734`	0.000	0.999	0.001
rs35925379 lBF = `0.00697383` Chr`8` : `144,802,456`	0.001	0.999	0.000
rs4596632 lBF = `-0.180907` Chr`8` : `132,353,735`	0.001	0.999	0.000
rs1018836 lBF = `-0.203138` Chr`8` : `91,570,362`	0.000	0.999	0.001
rs10112481 lBF = `-0.00967733` Chr`8` : `4,875,172`	0.001	0.999	0.000
rs1154053 lBF = `-0.127846` Chr`8` : `4,285,390`	0.001	0.999	0.000
rs2077212 lBF = `-0.0761477` Chr`8` : `5,982,272`	0.000	0.999	0.001
rs4601292 lBF = `-0.086781` Chr`8` : `66,851,731`	0.001	0.999	0.000
rs4705 lBF = `-0.15889` Chr`8` : `17,500,223`	0.001	0.999	0.000
rs2255327 lBF = `0.00125341` Chr`8` : `11,409,992`	0.001	0.999	0.000
rs11786458 lBF = `-0.0978238` Chr`8` : `40,252,701`	0.001	0.999	0.000
rs1045529 lBF = `5.22358` Chr`8` : `8,890,098`	0.000	0.999	0.001
rs4736655 lBF = `0.00621516` Chr`8` : `134,350,106`	0.000	0.999	0.001
rs7840202 lBF = `-0.111229` Chr`8` : `103,308,400`	0.001	0.999	0.000
rs7459527 lBF = `0.0042781` Chr`8` : `118,909,260`	0.000	0.999	0.001
rs117336177 lBF = `-0.0808828` Chr`8` : `66,701,846`	0.001	0.999	0.000
rs17749211 lBF = `0.76364` Chr`8` : `119,391,409`	0.001	0.999	0.001
rs16906293 lBF = `0.00227664` Chr`8` : `137,768,892`	0.001	0.999	0.000
rs2898261 lBF = `0.00118597` Chr`8` : `10,958,539`	0.001	0.999	0.000
rs72657954 lBF = `-0.00355337` Chr`8` : `72,770,306`	0.001	0.999	0.000
rs6990917 lBF = `0.00141955` Chr`8` : `68,799,377`	0.001	0.999	0.000
rs4922265 lBF = `-0.178149` Chr`8` : `16,996,435`	0.001	0.999	0.000
rs147913210 lBF = `0.00128782` Chr`8` : `25,130,233`	0.001	0.999	0.000
rs150335055 lBF = `0.00366638` Chr`8` : `9,244,264`	0.001	0.999	0.000
rs4873403 lBF = `0.00168804` Chr`8` : `50,974,319`	0.000	0.999	0.001
rs190951784 lBF = `0.00112187` Chr`8` : `25,131,523`	0.001	0.999	0.000
rs182115318 lBF = `0.00072777` Chr`8` : `25,128,723`	0.001	0.999	0.000
rs4733601 lBF = `-0.00528548` Chr`8` : `129,269,466`	0.001	0.999	0.000
rs77959025 lBF = `-0.0223877` Chr`8` : `128,761,169`	0.001	0.999	0.000
rs117809070 lBF = `-0.0258284` Chr`8` : `67,282,208`	0.001	0.999	0.000
rs11995572 lBF = `-0.08999` Chr`8` : `89,592,083`	0.001	0.999	0.000
rs73318770 lBF = `0.0005157` Chr`8` : `74,362,915`	0.001	0.999	0.000
rs28493987 lBF = `0.00011` Chr`8` : `75,341,097`	0.000	0.999	0.001
rs7004587 lBF = `0.00009449` Chr`8` : `108,040,352`	0.001	0.999	0.000
rs10107366 lBF = `0.00004624` Chr`8` : `99,113,687`	0.001	0.999	0.000
rs192316701 lBF = `0` Chr`8` : `1,456,068`	0.001	0.999	0.001
rs1845529 lBF = `0` Chr`8` : `116,163,863`	0.001	0.999	0.001
rs143335239 lBF = `0` Chr`8` : `6,500,809`	0.001	0.999	0.001
rs192994403 lBF = `0` Chr`8` : `76,211,333`	0.001	0.999	0.001
rs73313124 lBF = `0` Chr`8` : `110,478,822`	0.001	0.999	0.001
rs144424757 lBF = `0` Chr`8` : `12,929,793`	0.001	0.999	0.001
rs187636186 lBF = `0` Chr`8` : `73,002,468`	0.001	0.999	0.001
rs11986011 lBF = `0` Chr`8` : `127,332,657`	0.001	0.999	0.001
rs191631123 lBF = `0` Chr`8` : `32,443,704`	0.001	0.999	0.001
rs141721054 lBF = `0` Chr`8` : `131,201,613`	0.001	0.999	0.001
rs113414285 lBF = `0` Chr`8` : `24,395,263`	0.001	0.999	0.001
rs4128527 lBF = `0` Chr`8` : `72,682,693`	0.001	0.999	0.001
rs189590409 lBF = `0` Chr`8` : `114,727,602`	0.001	0.999	0.001
rs144222594 lBF = `0` Chr`8` : `12,931,504`	0.001	0.999	0.001
rs11989122 lBF = `0` Chr`8` : `118,827,839`	0.001	0.999	0.001
rs116129203 lBF = `0` Chr`8` : `6,779,323`	0.001	0.999	0.001
rs192074192 lBF = `0` Chr`8` : `73,025,833`	0.001	0.999	0.001
rs138094162 lBF = `0` Chr`8` : `6,489,568`	0.001	0.999	0.001
rs111754512 lBF = `0` Chr`8` : `24,400,648`	0.001	0.999	0.001
rs147852159 lBF = `0` Chr`8` : `146,171,164`	0.001	0.999	0.001
rs150435906 lBF = `0` Chr`8` : `66,864,338`	0.001	0.999	0.001
rs201734206 lBF = `0` Chr`8` : `73,984,100`	0.001	0.999	0.001
rs188858915 lBF = `0` Chr`8` : `6,494,833`	0.001	0.999	0.001
rs7460090 lBF = `0` Chr`8` : `57,194,163`	0.001	0.999	0.001
rs182838111 lBF = `0` Chr`8` : `67,889,470`	0.001	0.999	0.001
rs183191361 lBF = `0` Chr`8` : `76,083,247`	0.001	0.999	0.001
rs79781504 lBF = `0` Chr`8` : `84,750,057`	0.001	0.999	0.001
rs16902104 lBF = `0` Chr`8` : `128,340,908`	0.001	0.999	0.001
rs188809019 lBF = `0` Chr`8` : `129,286,235`	0.001	0.999	0.001
rs191935895 lBF = `0` Chr`8` : `5,267,311`	0.001	0.999	0.001
rs76547188 lBF = `0` Chr`8` : `21,978,372`	0.001	0.999	0.001
rs113660214 lBF = `0` Chr`8` : `977,436`	0.001	0.999	0.001
rs114258913 lBF = `0` Chr`8` : `93,525,403`	0.001	0.999	0.001
rs182387400 lBF = `0` Chr`8` : `25,129,708`	0.001	0.999	0.001
rs182302106 lBF = `0` Chr`8` : `1,455,175`	0.001	0.999	0.001
rs147851892 lBF = `0` Chr`8` : `24,234,355`	0.001	0.999	0.001
rs141395649 lBF = `0` Chr`8` : `6,498,690`	0.001	0.999	0.001
rs114252942 lBF = `0` Chr`8` : `6,202,964`	0.001	0.999	0.001
rs116041037 lBF = `0` Chr`8` : `128,131,809`	0.001	0.999	0.001
rs75455452 lBF = `0` Chr`8` : `72,991,580`	0.001	0.999	0.001
rs8180991 lBF = `4.48006` Chr`8` : `126,500,350`	0.001	0.999	0.000
rs17359493 lBF = `0.154025` Chr`8` : `95,856,911`	0.001	0.999	0.000
rs7015622 lBF = `-0.00005111` Chr`8` : `83,903,814`	0.001	0.999	0.000
rs12542677 lBF = `-0.00007086` Chr`8` : `56,168,059`	0.001	0.999	0.000
rs16904316 lBF = `-0.00010131` Chr`8` : `131,617,850`	0.001	0.999	0.000
rs183529902 lBF = `-0.0001389` Chr`8` : `35,880,032`	0.001	0.999	0.000
rs4875284 lBF = `-0.00037851` Chr`8` : `3,978,130`	0.000	0.999	0.001
rs113367091 lBF = `-0.00039836` Chr`8` : `12,892,858`	0.001	0.999	0.000
rs186046079 lBF = `-0.00055881` Chr`8` : `6,468,714`	0.000	0.999	0.001
rs73302752 lBF = `-0.0447667` Chr`8` : `73,279,185`	0.001	0.999	0.000
rs6577655 lBF = `-0.0998599` Chr`8` : `135,593,725`	0.000	0.999	0.001
rs13254600 lBF = `-0.149406` Chr`8` : `124,089,526`	0.001	0.999	0.000
rs3739262 lBF = `4.35474` Chr`8` : `134,205,713`	0.000	0.999	0.001
rs804280 lBF = `0.0044552` Chr`8` : `11,612,698`	0.000	0.999	0.001
rs4397449 lBF = `-0.00020679` Chr`8` : `90,342,186`	0.001	0.999	0.000
rs151198427 lBF = `-0.00042403` Chr`8` : `68,351,787`	0.000	0.999	0.001
rs141088253 lBF = `-0.00045682` Chr`8` : `5,284,296`	0.000	0.999	0.000
rs4410871 lBF = `2.75086` Chr`8` : `128,815,029`	0.000	0.999	0.001
rs61496269 lBF = `-0.00255788` Chr`8` : `139,608,718`	0.000	0.999	0.001
rs17466684 lBF = `-0.0858153` Chr`8` : `27,452,847`	0.001	0.999	0.000
rs17581368 lBF = `-0.132769` Chr`8` : `21,662,445`	0.000	0.999	0.001
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rs10957961 lBF = `-0.0319862` Chr`8` : `81,031,822`	0.001	0.999	0.000
rs75729198 lBF = `-0.0399752` Chr`8` : `15,885,087`	0.000	0.999	0.000
rs3136739 lBF = `-0.0523605` Chr`8` : `42,205,080`	0.000	0.999	0.000
rs11994937 lBF = `-0.0560266` Chr`8` : `59,508,580`	0.000	0.999	0.000
rs4557697 lBF = `-0.0603882` Chr`8` : `63,843,631`	0.000	0.999	0.000
rs62495153 lBF = `-0.0634614` Chr`8` : `8,136,656`	0.000	0.999	0.000
rs1462872 lBF = `-0.0853125` Chr`8` : `31,794,109`	0.000	0.999	0.000
rs977396 lBF = `-0.0890414` Chr`8` : `105,992,696`	0.000	0.999	0.000
rs10216564 lBF = `-0.0953279` Chr`8` : `77,475,130`	0.000	0.999	0.000
rs9650068 lBF = `-0.0979417` Chr`8` : `117,643,773`	0.000	0.999	0.000
rs28727938 lBF = `-0.0989894` Chr`8` : `77,478,539`	0.000	0.999	0.000
rs7461897 lBF = `-0.125061` Chr`8` : `26,894,544`	0.000	0.999	0.000
rs1523643 lBF = `-0.160931` Chr`8` : `16,789,235`	0.000	0.999	0.000
rs28455997 lBF = `-0.175467` Chr`8` : `3,076,959`	0.001	0.999	0.000
rs6981717 lBF = `-0.178807` Chr`8` : `89,188,454`	0.001	0.999	0.000
rs1351356 lBF = `-0.200508` Chr`8` : `118,600,122`	0.000	0.999	0.001
rs6473227 lBF = `16.8553` Chr`8` : `81,285,892`	0.000	0.999	0.000
rs2953805 lBF = `4.94383` Chr`8` : `8,914,757`	0.000	0.999	0.000
rs9314308 lBF = `0.571474` Chr`8` : `25,544,679`	0.001	0.999	0.000
rs117531883 lBF = `0.0315426` Chr`8` : `8,309,054`	0.000	0.999	0.000
rs117206365 lBF = `0.0231065` Chr`8` : `126,883,835`	0.000	0.999	0.000
rs11773966 lBF = `0.00598648` Chr`8` : `54,555,200`	0.000	0.999	0.000
rs7013415 lBF = `0.00435299` Chr`8` : `73,038,451`	0.000	0.999	0.000
rs138042437 lBF = `-0.00974022` Chr`8` : `128,208,369`	0.000	0.999	0.000
rs17372597 lBF = `-0.0187268` Chr`8` : `125,595,153`	0.000	0.999	0.000
rs62501302 lBF = `-0.0258544` Chr`8` : `50,545,426`	0.000	0.999	0.000
rs3019286 lBF = `-0.0265394` Chr`8` : `99,895,405`	0.000	0.999	0.000
rs116237496 lBF = `-0.0266402` Chr`8` : `102,045,915`	0.000	0.999	0.000
rs2648908 lBF = `-0.0267547` Chr`8` : `129,127,594`	0.000	0.999	0.000
rs34975555 lBF = `-0.0368748` Chr`8` : `17,858,297`	0.000	0.999	0.000
rs76670418 lBF = `-0.0460537` Chr`8` : `60,334,045`	0.000	0.999	0.000
rs9918841 lBF = `-0.0629745` Chr`8` : `91,193,959`	0.000	0.999	0.000
rs144606178 lBF = `-0.0834796` Chr`8` : `1,299,878`	0.000	0.999	0.000
rs56109708 lBF = `-0.0845517` Chr`8` : `140,438,978`	0.000	0.999	0.000
rs440837 lBF = `-0.0868853` Chr`8` : `81,461,974`	0.000	0.999	0.000
rs1909881 lBF = `-0.104571` Chr`8` : `96,515,888`	0.000	0.999	0.000
rs1042992 lBF = `-0.110388` Chr`8` : `26,269,191`	0.001	0.999	0.000
rs11998649 lBF = `-0.133488` Chr`8` : `22,619,551`	0.000	0.999	0.000
rs240657 lBF = `-0.137437` Chr`8` : `15,665,612`	0.000	0.999	0.000
rs13253111 lBF = `-0.13856` Chr`8` : `28,061,974`	0.000	0.999	0.001
rs189798 lBF = `1.62108` Chr`8` : `8,990,577`	0.000	0.999	0.000
rs117577998 lBF = `0.122691` Chr`8` : `143,505,653`	0.000	0.999	0.000
rs75609241 lBF = `0.111133` Chr`8` : `29,082,285`	0.000	0.999	0.000
rs10097731 lBF = `0.0529343` Chr`8` : `82,027,672`	0.000	0.999	0.000
rs10108669 lBF = `0.0140556` Chr`8` : `108,685,885`	0.000	0.999	0.000
rs118182320 lBF = `-0.00211438` Chr`8` : `80,951,882`	0.000	0.999	0.000
rs62532816 lBF = `-0.00261166` Chr`8` : `132,554,452`	0.000	0.999	0.000
rs79512063 lBF = `-0.00476336` Chr`8` : `89,533,747`	0.000	0.999	0.000
rs187899339 lBF = `-0.00904718` Chr`8` : `111,118,450`	0.000	0.999	0.000
rs9656829 lBF = `-0.0150877` Chr`8` : `93,602,448`	0.000	0.999	0.000
rs116086868 lBF = `-0.0282524` Chr`8` : `17,448,828`	0.000	0.999	0.000
rs79560598 lBF = `-0.0285144` Chr`8` : `40,540,751`	0.000	0.999	0.000
rs11136341 lBF = `-0.0366032` Chr`8` : `145,043,543`	0.000	0.999	0.000
rs74617895 lBF = `-0.0374659` Chr`8` : `3,646,688`	0.000	0.999	0.000
rs11986220 lBF = `-0.0512055` Chr`8` : `128,531,689`	0.000	0.999	0.000
rs10090154 lBF = `-0.0548148` Chr`8` : `128,532,137`	0.000	0.999	0.000
rs10109725 lBF = `-0.0549739` Chr`8` : `3,364,038`	0.000	0.999	0.000
rs1532423 lBF = `-0.0565578` Chr`8` : `86,268,313`	0.000	0.999	0.000
rs112505062 lBF = `-0.0574782` Chr`8` : `96,293,103`	0.000	0.999	0.000
rs62502258 lBF = `-0.0663951` Chr`8` : `23,852,510`	0.000	0.999	0.000
rs11782652 lBF = `-0.0773709` Chr`8` : `82,653,644`	0.000	0.999	0.000
rs4909764 lBF = `-0.0821014` Chr`8` : `139,255,918`	0.000	0.999	0.000
rs73198922 lBF = `-0.0948602` Chr`8` : `10,958,663`	0.000	0.999	0.000
rs2122469 lBF = `-0.0989887` Chr`8` : `20,626,321`	0.000	0.999	0.000
rs10095849 lBF = `-0.115005` Chr`8` : `39,408,586`	0.000	0.999	0.000
rs1585518 lBF = `-0.116403` Chr`8` : `120,475,238`	0.000	0.999	0.000
rs4732957 lBF = `-0.118194` Chr`8` : `26,718,880`	0.000	0.999	0.000
rs7815720 lBF = `-0.120369` Chr`8` : `118,089,513`	0.000	0.999	0.000
rs3793427 lBF = `-0.145541` Chr`8` : `17,143,830`	0.000	0.999	0.000
rs1996720 lBF = `-0.152984` Chr`8` : `113,074,096`	0.000	0.999	0.000
rs2683295 lBF = `-0.1725` Chr`8` : `19,077,830`	0.000	0.999	0.000
rs2407314 lBF = `-0.202351` Chr`8` : `4,078,353`	0.000	0.999	0.000
rs11780156 lBF = `4.14602` Chr`8` : `129,194,641`	0.000	0.999	0.000
rs6601327 lBF = `3.73287` Chr`8` : `9,395,532`	0.000	0.999	0.000
rs2055729 lBF = `0.430859` Chr`8` : `9,792,662`	0.000	0.999	0.000
rs17829719 lBF = `0.142146` Chr`8` : `1,824,454`	0.000	0.999	0.000
rs16924527 lBF = `0.0920009` Chr`8` : `59,974,175`	0.000	0.999	0.000
rs7011581 lBF = `0.0491724` Chr`8` : `9,000,465`	0.000	0.999	0.000
rs181166265 lBF = `0.0425669` Chr`8` : `80,985,035`	0.000	0.999	0.000
rs117405208 lBF = `0.0355189` Chr`8` : `134,967,408`	0.000	0.999	0.000
rs75583295 lBF = `0.00980577` Chr`8` : `63,596,650`	0.000	0.999	0.000
rs7835454 lBF = `0.00728623` Chr`8` : `40,034,434`	0.000	0.999	0.000
rs10108954 lBF = `-0.00002642` Chr`8` : `8,722,378`	0.000	0.999	0.000
rs830478 lBF = `-0.00334354` Chr`8` : `73,372,875`	0.000	0.999	0.000
rs76316943 lBF = `-0.00450821` Chr`8` : `117,848,307`	0.000	0.999	0.000
rs77173849 lBF = `-0.0151183` Chr`8` : `47,021,723`	0.000	0.999	0.000
rs117366179 lBF = `-0.0167841` Chr`8` : `14,733,658`	0.000	0.999	0.000
rs2106212 lBF = `-0.0199846` Chr`8` : `12,569,241`	0.000	0.999	0.000
rs142487520 lBF = `-0.0210214` Chr`8` : `9,274,376`	0.000	0.999	0.000
rs118149821 lBF = `-0.0216763` Chr`8` : `85,276,067`	0.000	0.999	0.000
rs16867579 lBF = `-0.0224251` Chr`8` : `102,375,267`	0.000	0.999	0.000
rs140355816 lBF = `-0.0267756` Chr`8` : `117,574,515`	0.000	0.999	0.000
rs10504249 lBF = `-0.0284104` Chr`8` : `58,789,081`	0.000	0.999	0.000
rs117956319 lBF = `-0.0288101` Chr`8` : `32,191,896`	0.000	0.999	0.000
rs16887244 lBF = `-0.0294591` Chr`8` : `38,031,345`	0.000	0.999	0.000
rs6990255 lBF = `-0.0298253` Chr`8` : `34,126,948`	0.000	0.999	0.000
rs150639459 lBF = `-0.0306524` Chr`8` : `18,804,686`	0.000	0.999	0.000
rs7011192 lBF = `-0.0320036` Chr`8` : `10,535,377`	0.000	0.999	0.000

This table lists the top 500 variants ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Parent term	Heart valve problem/heart murmur
Nested terms	Aortic stenosis Aortic regurgitation / incompetence

Diagnostic term associations

Self-Reported Statistics (`SRS`)

Diagnostic term associations

Self-Reported Statistics (SRS)

Self-Reported Statistics (`SRS`)